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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116631028
log Bayes Factor = 11.4875
Chromosome 1   position 81,019,150  (GRCh37) Explore rs116631028 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.998 0.002 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.995 0.005 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
C78.0 Secondary malignant neoplasm of lung
0.994 0.006 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.991 0.009 0.000
Chapter XX External causes of morbidity and mortality
0.989 0.011 0.000
F41 Other anxiety disorders
0.977 0.023 0.000
Chapter X Diseases of the respiratory system
0.973 0.027 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.972 0.028 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.969 0.031 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.965 0.035 0.000
Chapter VII Diseases of the eye and adnexa
0.959 0.041 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.958 0.042 0.000
A00-A09 Intestinal infectious diseases
0.955 0.045 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.954 0.046 0.000
R26 Abnormalities of gait and mobility
0.953 0.047 0.000
J09-J18 Influenza and pneumonia
0.949 0.051 0.000
M45-M49 Spondylopathies
0.947 0.053 0.000
R47-R49 Symptoms and signs involving speech and voice
0.945 0.055 0.000
C51-C58 Malignant neoplasms of female genital organs
0.944 0.056 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.942 0.058 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.939 0.061 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.929 0.071 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.928 0.072 0.000
M47 Spondylosis
0.927 0.073 0.000
H40-H42 Glaucoma
0.925 0.075 0.000
F41.9 Anxiety disorder, unspecified
0.925 0.075 0.000
R47 Speech disturbances, not elsewhere classified
0.919 0.081 0.000
M80-M85 Disorders of bone density and structure
0.919 0.081 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.917 0.083 0.000
Y43 Primarily systemic agents
0.913 0.087 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.912 0.088 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.910 0.090 0.000
W00-W19 Falls
0.910 0.090 0.000
C77.5 Intrapelvic lymph nodes
0.910 0.090 0.000
Chapter VIII Diseases of the ear and mastoid process
0.905 0.095 0.000
S00-S09 Injuries to the head
0.904 0.096 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.904 0.096 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.903 0.097 0.000
H40 Glaucoma
0.901 0.099 0.000
E10-E14 Diabetes mellitus
0.893 0.107 0.000
Y43.3 Other antineoplastic drugs
0.884 0.116 0.000
R41.0 Disorientation, unspecified
0.880 0.120 0.000
J18 Pneumonia, organism unspecified
0.879 0.121 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.878 0.122 0.000
M47.9 Spondylosis, unspecified
0.875 0.125 0.000
C56 Malignant neoplasm of ovary
0.875 0.125 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.873 0.127 0.000
H40.2 Primary angle-closure glaucoma
0.873 0.127 0.000
R47.0 Dysphasia and aphasia
0.871 0.129 0.000
A80-A89 Viral infections of the central nervous system
0.870 0.130 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.869 0.131 0.000
R25 Abnormal involuntary movements
0.869 0.131 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.867 0.133 0.000
B15-B19 Viral hepatitis
0.866 0.134 0.000
F41.2 Mixed anxiety and depressive disorder
0.864 0.136 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.858 0.142 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.858 0.142 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.850 0.150 0.000
S10-S19 Injuries to the neck
0.848 0.152 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.845 0.155 0.000
M81 Osteoporosis without pathological fracture
0.844 0.156 0.000
C77.2 Intra-abdominal lymph nodes
0.843 0.157 0.000
E11 Non-insulin-dependent diabetes mellitus
0.840 0.160 0.000
M48 Other spondylopathies
0.839 0.161 0.000
J18.1 Lobar pneumonia, unspecified
0.837 0.163 0.000
C77.1 Intrathoracic lymph nodes
0.837 0.163 0.000
D46 Myelodysplastic syndromes
0.837 0.163 0.000
F30-F39 Mood [affective] disorders
0.835 0.165 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.833 0.167 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.832 0.168 0.000
T66-T78 Other and unspecified effects of external causes
0.831 0.169 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.829 0.171 0.000
M47.8 Other spondylosis
0.828 0.172 0.000
B35-B49 Mycoses
0.828 0.172 0.000
F10.0 Acute intoxication
0.826 0.174 0.000
F43 Reaction to severe stress, and adjustment disorders
0.825 0.175 0.000
C78.2 Secondary malignant neoplasm of pleura
0.825 0.175 0.000
H60-H62 Diseases of external ear
0.823 0.177 0.000
C15-C26 Malignant neoplasms of digestive organs
0.821 0.179 0.000
C78.7 Secondary malignant neoplasm of liver
0.821 0.179 0.000
X60-X84 Intentional self-harm
0.821 0.179 0.000
S40-S49 Injuries to the shoulder and upper arm
0.820 0.180 0.000
E16 Other disorders of pancreatic internal secretion
0.816 0.184 0.000
F10.3 Withdrawal state
0.814 0.186 0.000
W20-W49 Exposure to inanimate mechanical forces
0.814 0.186 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.813 0.187 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.810 0.190 0.000
E10 Insulin-dependent diabetes mellitus
0.809 0.191 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.809 0.191 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.809 0.191 0.000
M80 Osteoporosis with pathological fracture
0.808 0.192 0.000
C80 Malignant neoplasm without specification of site
0.806 0.194 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.804 0.196 0.000
F40 Phobic anxiety disorders
0.804 0.196 0.000
S80-S89 Injuries to the knee and lower leg
0.803 0.197 0.000
H30-H36 Disorders of choroid and retina
0.802 0.198 0.000
F80-F89 Disorders of psychological development
0.800 0.200 0.000
R40 Somnolence, stupor and coma
0.795 0.205 0.000
R47.1 Dysarthria and anarthria
0.795 0.205 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.794 0.206 0.000
R27 Other lack of coordination
0.792 0.208 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.792 0.208 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.791 0.209 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.791 0.209 0.000
T39.1 4-Aminophenol derivatives
0.789 0.211 0.000
W19 Unspecified fall
0.788 0.212 0.000
M81.9 Osteoporosis, unspecified
0.787 0.213 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.783 0.217 0.000
M47.82 Other spondylosis (Cervical region)
0.782 0.218 0.000
J95-J99 Other diseases of the respiratory system
0.782 0.218 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.781 0.219 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.780 0.220 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.780 0.220 0.000
R42 Dizziness and giddiness
0.777 0.223 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.776 0.224 0.000
O00-O08 Pregnancy with abortive outcome
0.774 0.226 0.000
B18 Chronic viral hepatitis
0.774 0.226 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.773 0.227 0.000
T36 Poisoning by systemic antibiotics
0.772 0.228 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.771 0.229 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.768 0.232 0.000
R25.1 Tremor, unspecified
0.768 0.232 0.000
Chapter XXII Codes for special purposes
0.766 0.234 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.765 0.235 0.000
M48.0 Spinal stenosis
0.761 0.239 0.000
Chapter VI Diseases of the nervous system
0.761 0.239 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.761 0.239 0.000
S06 Intracranial injury
0.760 0.240 0.000
H65-H75 Diseases of middle ear and mastoid
0.760 0.240 0.000
J15.4 Pneumonia due to other streptococci
0.760 0.240 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.759 0.241 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.759 0.241 0.000
E16.2 Hypoglycaemia, unspecified
0.758 0.242 0.000
H40.5 Glaucoma secondary to other eye disorders
0.758 0.242 0.000
J60-J70 Lung diseases due to external agents
0.755 0.245 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.754 0.246 0.000
E20-E35 Disorders of other endocrine glands
0.753 0.247 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.750 0.250 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.749 0.251 0.000
R26.3 Immobility
0.747 0.253 0.000
V40-V49 Car occupant injured in transport accident
0.745 0.255 0.000
S20-S29 Injuries to the thorax
0.744 0.256 0.000
M60-M63 Disorders of muscles
0.744 0.256 0.000
A30-A49 Other bacterial diseases
0.743 0.257 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.741 0.259 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.740 0.260 0.000
A08 Viral and other specified intestinal infections
0.740 0.260 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.740 0.260 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.740 0.260 0.000
H61 Other disorders of external ear
0.739 0.261 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.737 0.263 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.736 0.264 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.736 0.264 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.736 0.264 0.000
M47.2 Other spondylosis with radiculopathy
0.736 0.264 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.736 0.264 0.000
J00-J06 Acute upper respiratory infections
0.735 0.265 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.735 0.265 0.000
C45 Mesothelioma
0.734 0.266 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.734 0.266 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.734 0.266 0.000
E11.3 With ophthalmic complications
0.733 0.267 0.000
O04 Medical abortion
0.733 0.267 0.000
S00 Superficial injury of head
0.732 0.268 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.731 0.269 0.000
E11.1 With ketoacidosis
0.730 0.270 0.000
H35 Other retinal disorders
0.728 0.272 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.728 0.272 0.000
F60-F69 Disorders of adult personality and behaviour
0.726 0.273 0.000
E11.4 With neurological complications
0.726 0.274 0.000
G40-G47 Episodic and paroxysmal disorders
0.726 0.274 0.000
H40.0 Glaucoma suspect
0.726 0.274 0.000
J90-J94 Other diseases of pleura
0.725 0.275 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.725 0.275 0.000
A87 Viral meningitis
0.725 0.275 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.725 0.275 0.000
F11 Mental and behavioural disorders due to use of opioids
0.725 0.275 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.723 0.276 0.000
E10.9 Without complications
0.721 0.279 0.000
A86 Unspecified viral encephalitis
0.717 0.283 0.000
C54 Malignant neoplasm of corpus uteri
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
F45 Somatoform disorders
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
J18.0 Bronchopneumonia, unspecified
0.716 0.284 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.716 0.284 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.713 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.713 0.286 0.000
B65-B83 Helminthiases
0.713 0.286 0.000
B50-B64 Protozoal diseases
0.713 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.713 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.713 0.286 0.000
A75-A79 Rickettsioses
0.713 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.713 0.286 0.000
A65-A69 Other spirochaetal diseases
0.713 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.713 0.286 0.000
A15-A19 Tuberculosis
0.713 0.286 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.713 0.287 0.000
W06 Fall involving bed
0.713 0.287 0.000
S50-S59 Injuries to the elbow and forearm
0.713 0.287 0.000
A02 Other Salmonella infections
0.712 0.288 0.000
F48 Other neurotic disorders
0.710 0.290 0.000
F44 Dissociative [conversion] disorders
0.710 0.290 0.000
F42 Obsessive-compulsive disorder
0.710 0.290 0.000
S80 Superficial injury of lower leg
0.709 0.291 0.000
C53 Malignant neoplasm of cervix uteri
0.709 0.291 0.000
X78 Intentional self-harm by sharp object
0.709 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
W50-W64 Exposure to animate mechanical forces
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
B37 Candidiasis
0.707 0.293 0.000
R47.8 Other and unspecified speech disturbances
0.707 0.293 0.000
C73 Malignant neoplasm of thyroid gland
0.707 0.293 0.000
E40-E46 Malnutrition
0.707 0.293 0.000
V10-V19 Pedal cyclist injured in transport accident
0.707 0.293 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.706 0.294 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.706 0.294 0.000
W13 Fall from, out of or through building or structure
0.705 0.295 0.000
O04.9 Complete or unspecified, without complication
0.704 0.296 0.000
S12 Fracture of neck
0.704 0.296 0.000
M86-M90 Other osteopathies
0.702 0.298 0.000
M46 Other inflammatory spondylopathies
0.702 0.298 0.000
C09 Malignant neoplasm of tonsil
0.701 0.298 0.000
Y57 Other and unspecified drugs and medicaments
0.701 0.299 0.000
W18 Other fall on same level
0.701 0.299 0.000
F41.8 Other specified anxiety disorders
0.700 0.299 0.000
F41.3 Other mixed anxiety disorders
0.700 0.299 0.000
E50-E64 Other nutritional deficiencies
0.699 0.300 0.000
C01 Malignant neoplasm of base of tongue
0.699 0.301 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.697 0.303 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.697 0.303 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.697 0.303 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.697 0.303 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.697 0.303 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.697 0.303 0.000
S05 Injury of eye and orbit
0.697 0.303 0.000
S09 Other and unspecified injuries of head
0.697 0.303 0.000
S60-S69 Injuries to the wrist and hand
0.697 0.303 0.000
M85 Other disorders of bone density and structure
0.696 0.304 0.000
M20-M25 Other joint disorders
0.696 0.304 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.696 0.304 0.000
R46 Symptoms and signs involving appearance and behaviour
0.694 0.306 0.000
R43 Disturbances of smell and taste
0.694 0.306 0.000
G43 Migraine
0.694 0.306 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.692 0.308 0.000
W22 Striking against or struck by other objects
0.692 0.308 0.000
W19.4 Street and highway
0.691 0.309 0.000
J14 Pneumonia due to Haemophilus influenzae
0.691 0.309 0.000
C17 Malignant neoplasm of small intestine
0.691 0.309 0.000
M05-M14 Inflammatory polyarthropathies
0.690 0.310 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.690 0.310 0.000
D41.0 Kidney
0.689 0.311 0.000
E11.2 With renal complications
0.688 0.312 0.000
B18.2 Chronic viral hepatitis C
0.687 0.313 0.000
T79-T79 Certain early complications of trauma
0.686 0.314 0.000
A07 Other protozoal intestinal diseases
0.684 0.315 0.000
A06 Amoebiasis
0.684 0.315 0.000
A05 Other bacterial foodborne intoxications
0.684 0.315 0.000
A03 Shigellosis
0.684 0.315 0.000
A01 Typhoid and paratyphoid fevers
0.684 0.315 0.000
A00 Cholera
0.684 0.315 0.000
Y59 Other and unspecified vaccines and biological substances
0.684 0.316 0.000
Y58 Bacterial vaccines
0.684 0.316 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.684 0.316 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.684 0.316 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.684 0.316 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.684 0.316 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.684 0.316 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.684 0.316 0.000
Y48 Anaesthetics and therapeutic gases
0.684 0.316 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.684 0.316 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.684 0.316 0.000
C80.9 Malignant neoplasm, unspecified
0.683 0.317 0.000
J15.2 Pneumonia due to staphylococcus
0.683 0.317 0.000
R26.1 Paralytic gait
0.683 0.317 0.000
R26.0 Ataxic gait
0.683 0.317 0.000
S02 Fracture of skull and facial bones
0.683 0.317 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.683 0.317 0.000
J30-J39 Other diseases of upper respiratory tract
0.682 0.318 0.000
H55-H59 Other disorders of eye and adnexa
0.681 0.319 0.000
J17 Pneumonia in diseases classified elsewhere
0.681 0.319 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.681 0.319 0.000
J12 Viral pneumonia, not elsewhere classified
0.681 0.319 0.000
J11 Influenza, virus not identified
0.681 0.319 0.000
J10 Influenza due to identified influenza virus
0.681 0.319 0.000
J09 Influenza due to certain identified influenza virus
0.681 0.319 0.000
M49 Spondylopathies in diseases classified elsewhere
0.679 0.321 0.000
D39.1 Ovary
0.679 0.321 0.000
H35.8 Other specified retinal disorders
0.678 0.322 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.678 0.322 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.678 0.322 0.000
C77.4 Inguinal and lower limb lymph nodes
0.678 0.322 0.000
R25.3 Fasciculation
0.677 0.323 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.677 0.323 0.000
C51 Malignant neoplasm of vulva
0.677 0.323 0.000
C58 Malignant neoplasm of placenta
0.677 0.323 0.000
C52 Malignant neoplasm of vagina
0.677 0.323 0.000
R82 Other abnormal findings in urine
0.676 0.323 0.000
G43.9 Migraine, unspecified
0.676 0.324 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.675 0.324 0.000
C26.0 Intestinal tract, part unspecified
0.674 0.326 0.000
H53-H54 Visual disturbances and blindness
0.674 0.326 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.674 0.326 0.000
R29.4 Clicking hip
0.673 0.326 0.000
R29.3 Abnormal posture
0.673 0.326 0.000
R29.2 Abnormal reflex
0.673 0.326 0.000
R29.1 Meningismus
0.673 0.326 0.000
R29.0 Tetany
0.673 0.326 0.000
O03 Spontaneous abortion
0.673 0.327 0.000
T78 Adverse effects, not elsewhere classified
0.672 0.328 0.000
H40.1 Primary open-angle glaucoma
0.671 0.329 0.000
F40.2 Specific (isolated) phobias
0.670 0.329 0.000
W10 Fall on and from stairs and steps
0.670 0.330 0.000
S42 Fracture of shoulder and upper arm
0.670 0.330 0.000
M45 Ankylosing spondylitis
0.670 0.330 0.000
C77.8 Lymph nodes of multiple regions
0.669 0.331 0.000
T43.2 Other and unspecified antidepressants
0.668 0.332 0.000
H10-H13 Disorders of conjunctiva
0.667 0.333 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.667 0.333 0.000
F10.2 Dependence syndrome
0.667 0.333 0.000
F32 Depressive episode
0.667 0.333 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.667 0.333 0.000
B07 Viral warts
0.666 0.334 0.000
E00-E07 Disorders of thyroid gland
0.666 0.334 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.666 0.334 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.666 0.334 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.666 0.334 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.666 0.334 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.666 0.334 0.000
M47.1 Other spondylosis with myelopathy
0.665 0.335 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.665 0.335 0.000
F33 Recurrent depressive disorder
0.664 0.336 0.000
H42 Glaucoma in diseases classified elsewhere
0.663 0.336 0.000
E11.5 With peripheral circulatory complications
0.663 0.337 0.000
C25 Malignant neoplasm of pancreas
0.662 0.338 0.000
H43-H45 Disorders of vitreous body and globe
0.662 0.338 0.000
M91-M94 Chondropathies
0.661 0.339 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.661 0.339 0.000
Y45.1 Salicylates
0.660 0.340 0.000
S90-S99 Injuries to the ankle and foot
0.660 0.340 0.000
M83 Adult osteomalacia
0.659 0.341 0.000
M82 Osteoporosis in diseases classified elsewhere
0.659 0.341 0.000
F43.0 Acute stress reaction
0.659 0.341 0.000
T68 Hypothermia
0.658 0.342 0.000
H60 Otitis externa
0.658 0.342 0.000
F81 Specific developmental disorders of scholastic skills
0.658 0.342 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.658 0.342 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.658 0.342 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.658 0.342 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.658 0.342 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.658 0.342 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.658 0.342 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.658 0.342 0.000
F30 Manic episode
0.657 0.343 0.000
F50 Eating disorders
0.655 0.345 0.000
M22 Disorders of patella
0.655 0.345 0.000
Y43.9 Primarily systemic agent, unspecified
0.655 0.345 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.655 0.345 0.000
Y43.6 Enzymes, not elsewhere classified
0.655 0.345 0.000
Y43.5 Acidifying and alkalising agents
0.655 0.345 0.000
Y43.4 Immunosuppressive agents
0.655 0.345 0.000
Y43.2 Antineoplastic natural products
0.655 0.345 0.000
Y43.1 Antineoplastic antimetabolites
0.655 0.345 0.000
Y43.0 Antiallergic and antiemetic drugs
0.655 0.345 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.654 0.346 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.653 0.347 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.653 0.347 0.000
B95-B98 Bacterial, viral and other infectious agents
0.653 0.347 0.000
M84 Disorders of continuity of bone
0.653 0.347 0.000
W17 Other fall from one level to another
0.652 0.347 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.652 0.347 0.000
W15 Fall from cliff
0.652 0.347 0.000
W14 Fall from tree
0.652 0.347 0.000
W12 Fall on and from scaffolding
0.652 0.347 0.000
W11 Fall on and from ladder
0.652 0.347 0.000
W09 Fall involving playground equipment
0.652 0.347 0.000
W08 Fall involving other furniture
0.652 0.347 0.000
W07 Fall involving chair
0.652 0.347 0.000
W05 Fall involving wheelchair
0.652 0.347 0.000
W04 Fall while being carried or supported by other persons
0.652 0.347 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.652 0.347 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.652 0.347 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.652 0.347 0.000
W00 Fall on same level involving ice and snow
0.652 0.347 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.652 0.348 0.000
F43.1 Posttraumatic stress disorder
0.651 0.349 0.000
R27.0 Ataxia, unspecified
0.651 0.349 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.650 0.350 0.000
G90-G99 Other disorders of the nervous system
0.650 0.350 0.000
R80 Isolated proteinuria
0.650 0.350 0.000
S80.0 Contusion of knee
0.650 0.350 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.649 0.351 0.000
D45 Polycythaemia vera
0.648 0.351 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.648 0.351 0.000
S08 Traumatic amputation of part of head
0.648 0.352 0.000
S07 Crushing injury of head
0.648 0.352 0.000
S04 Injury of cranial nerves
0.648 0.352 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.648 0.352 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.648 0.352 0.000
C45.0 Mesothelioma of pleura
0.648 0.352 0.000
R40.2 Coma, unspecified
0.648 0.352 0.000
R41.2 Retrograde amnesia
0.648 0.352 0.000
R41.1 Anterograde amnesia
0.648 0.352 0.000
H90-H95 Other disorders of ear
0.648 0.352 0.000
V20-V29 Motorcycle rider injured in transport accident
0.647 0.353 0.000
T92 Sequelae of injuries of upper limb
0.647 0.353 0.000
H40.8 Other glaucoma
0.646 0.354 0.000
H40.6 Glaucoma secondary to drugs
0.646 0.354 0.000
H40.4 Glaucoma secondary to eye inflammation
0.646 0.354 0.000
H40.3 Glaucoma secondary to eye trauma
0.646 0.354 0.000
R45 Symptoms and signs involving emotional state
0.646 0.354 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.645 0.355 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.644 0.355 0.000
E10.1 With ketoacidosis
0.642 0.358 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.642 0.358 0.000
E12 Malnutrition-related diabetes mellitus
0.641 0.359 0.000
R29.6 Tendency to fall, not elsewhere classified
0.641 0.359 0.000
S70-S79 Injuries to the hip and thigh
0.640 0.359 0.000
C77.0 Lymph nodes of head, face and neck
0.640 0.360 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.640 0.360 0.000
C79 Secondary malignant neoplasm of other sites
0.639 0.360 0.000
Y52 Agents primarily affecting the cardiovascular system
0.639 0.361 0.000
T51 Toxic effect of alcohol
0.638 0.362 0.000
E13 Other specified diabetes mellitus
0.635 0.364 0.000
F41.1 Generalised anxiety disorder
0.635 0.365 0.000
S06.5 Traumatic subdural haemorrhage
0.634 0.366 0.000
C69 Malignant neoplasm of eye and adnexa
0.634 0.366 0.000
M48.09 Spinal stenosis (Site unspecified)
0.634 0.366 0.000
H20 Iridocyclitis
0.634 0.366 0.000
C71 Malignant neoplasm of brain
0.633 0.366 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.633 0.367 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.632 0.367 0.000
Y40 Systemic antibiotics
0.631 0.368 0.000
H66 Suppurative and unspecified otitis media
0.631 0.369 0.000
J18.8 Other pneumonia, organism unspecified
0.631 0.369 0.000
J18.2 Hypostatic pneumonia, unspecified
0.631 0.369 0.000
S19 Other and unspecified injuries of neck
0.630 0.370 0.000
F10.9 Unspecified mental and behavioural disorder
0.629 0.370 0.000
F10.8 Other mental and behavioural disorders
0.629 0.370 0.000
F10.7 Residual and late-onset psychotic disorder
0.629 0.370 0.000
F10.6 Amnesic syndrome
0.629 0.370 0.000
F10.5 Psychotic disorder
0.629 0.370 0.000
F10.4 Withdrawal state with delirium
0.629 0.370 0.000
M48.06 Spinal stenosis (Lumbar region)
0.630 0.370 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.629 0.371 0.000
C77.9 Lymph node, unspecified
0.629 0.371 0.000
T36.0 Penicillins
0.629 0.371 0.000
H61.8 Other specified disorders of external ear
0.629 0.371 0.000
X78.0 Home
0.629 0.371 0.000
R44.1 Visual hallucinations
0.628 0.372 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.628 0.372 0.000
M24 Other specific joint derangements
0.628 0.372 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.628 0.372 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.628 0.372 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.628 0.372 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.628 0.372 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.628 0.372 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.628 0.372 0.000
H36 Retinal disorders in diseases classified elsewhere
0.625 0.374 0.000
C77.3 Axillary and upper limb lymph nodes
0.625 0.375 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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