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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116682995
log Bayes Factor = 11.6388
Chromosome 6   position 7,811,326  (GRCh37) Explore rs116682995 on Ensembl!
Variant rs116682995 is part of Cluster X0046

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
S00-S09 Injuries to the head
0.999 0.001 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.998 0.002 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.995 0.005 0.000
M20-M25 Other joint disorders
0.991 0.009 0.000
F10.2 Dependence syndrome
0.988 0.012 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.982 0.018 0.000
M50-M54 Other dorsopathies
0.982 0.018 0.000
M54 Dorsalgia
0.976 0.024 0.000
M23 Internal derangement of knee
0.966 0.034 0.000
S00 Superficial injury of head
0.955 0.045 0.000
S06 Intracranial injury
0.953 0.047 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.953 0.047 0.000
T39.1 4-Aminophenol derivatives
0.949 0.051 0.000
Chapter VIII Diseases of the ear and mastoid process
0.943 0.057 0.000
M24 Other specific joint derangements
0.937 0.063 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.936 0.064 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.935 0.065 0.000
M23.3 Other meniscus derangements
0.929 0.071 0.000
M54.5 Low back pain
0.926 0.074 0.000
S09 Other and unspecified injuries of head
0.924 0.076 0.000
M23.8 Other internal derangements of knee
0.923 0.077 0.000
Chapter IX Diseases of the circulatory system
0.923 0.077 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.916 0.084 0.000
F60-F69 Disorders of adult personality and behaviour
0.909 0.091 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.908 0.092 0.000
M54.57 Low back pain (Lumbosacral region)
0.906 0.094 0.000
S70-S79 Injuries to the hip and thigh
0.899 0.101 0.000
F10.0 Acute intoxication
0.898 0.102 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.898 0.102 0.000
F10.4 Withdrawal state with delirium
0.892 0.108 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.891 0.109 0.000
M54.9 Dorsalgia, unspecified
0.887 0.113 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.886 0.114 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.886 0.114 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.885 0.115 0.000
M54.1 Radiculopathy
0.883 0.117 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.878 0.122 0.000
Chapter VI Diseases of the nervous system
0.878 0.122 0.000
Y40 Systemic antibiotics
0.878 0.122 0.000
F10.3 Withdrawal state
0.871 0.129 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.870 0.130 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.870 0.130 0.000
T51 Toxic effect of alcohol
0.867 0.133 0.000
M21 Other acquired deformities of limbs
0.864 0.136 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.861 0.139 0.000
S02 Fracture of skull and facial bones
0.855 0.145 0.000
M45-M49 Spondylopathies
0.855 0.145 0.000
S01 Open wound of head
0.854 0.146 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.852 0.148 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.852 0.148 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.851 0.149 0.000
F80-F89 Disorders of psychological development
0.850 0.150 0.000
S09.9 Unspecified injury of head
0.848 0.152 0.000
F60 Specific personality disorders
0.844 0.156 0.000
F30-F39 Mood [affective] disorders
0.843 0.157 0.000
T39.0 Salicylates
0.842 0.158 0.000
H80-H83 Diseases of inner ear
0.838 0.162 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.835 0.165 0.000
S60-S69 Injuries to the wrist and hand
0.835 0.165 0.000
H65-H75 Diseases of middle ear and mastoid
0.833 0.167 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.833 0.167 0.000
E65-E68 Obesity and other hyperalimentation
0.830 0.170 0.000
S10-S19 Injuries to the neck
0.828 0.172 0.000
I60-I69 Cerebrovascular diseases
0.825 0.175 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.822 0.178 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.821 0.179 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.821 0.179 0.000
T51.0 Ethanol
0.817 0.183 0.000
G40-G47 Episodic and paroxysmal disorders
0.816 0.184 0.000
F43 Reaction to severe stress, and adjustment disorders
0.815 0.185 0.000
S06.3 Focal brain injury
0.813 0.187 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.811 0.189 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.811 0.189 0.000
V10-V19 Pedal cyclist injured in transport accident
0.810 0.190 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.809 0.191 0.000
E66 Obesity
0.809 0.191 0.000
S06.0 Concussion
0.809 0.191 0.000
M80-M85 Disorders of bone density and structure
0.807 0.193 0.000
E50-E64 Other nutritional deficiencies
0.806 0.194 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.805 0.195 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.804 0.196 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.804 0.196 0.000
S00.1 Contusion of eyelid and periocular area
0.803 0.196 0.000
S72 Fracture of femur
0.803 0.197 0.000
S50-S59 Injuries to the elbow and forearm
0.802 0.198 0.000
W00-W19 Falls
0.801 0.199 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.801 0.199 0.000
S90-S99 Injuries to the ankle and foot
0.798 0.202 0.000
S06.5 Traumatic subdural haemorrhage
0.797 0.202 0.000
G47 Sleep disorders
0.797 0.203 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.794 0.206 0.000
S00.9 Superficial injury of head, part unspecified
0.794 0.206 0.000
M53 Other dorsopathies, not elsewhere classified
0.794 0.206 0.000
M31 Other necrotising vasculopathies
0.793 0.207 0.000
M33 Dermatopolymyositis
0.793 0.207 0.000
F10.1 Harmful use
0.792 0.208 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.792 0.208 0.000
I73 Other peripheral vascular diseases
0.790 0.210 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.789 0.211 0.000
F60.3 Emotionally unstable personality disorder
0.789 0.211 0.000
F99-F99 Unspecified mental disorder
0.787 0.213 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.787 0.213 0.000
F31 Bipolar affective disorder
0.783 0.217 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.783 0.217 0.000
G47.3 Sleep apnoea
0.782 0.218 0.000
Y40.0 Penicillins
0.778 0.222 0.000
W50-W64 Exposure to animate mechanical forces
0.778 0.222 0.000
I72 Other aneurysm
0.773 0.227 0.000
H90-H95 Other disorders of ear
0.772 0.228 0.000
F70-F79 Mental retardation
0.772 0.228 0.000
I74 Arterial embolism and thrombosis
0.772 0.228 0.000
M54.16 Radiculopathy (Lumbar region)
0.771 0.229 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.769 0.231 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.768 0.232 0.000
Y45.1 Salicylates
0.767 0.233 0.000
V20-V29 Motorcycle rider injured in transport accident
0.767 0.233 0.000
M23.0 Cystic meniscus
0.766 0.234 0.000
M54.6 Pain in thoracic spine
0.765 0.235 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.765 0.235 0.000
S05 Injury of eye and orbit
0.764 0.236 0.000
F11 Mental and behavioural disorders due to use of opioids
0.764 0.236 0.000
K70-K77 Diseases of liver
0.763 0.237 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.763 0.237 0.000
M24.6 Ankylosis of joint
0.763 0.237 0.000
E66.8 Other obesity
0.761 0.239 0.000
Y40.9 Systemic antibiotic, unspecified
0.761 0.239 0.000
X50-X57 Overexertion, travel and privation
0.760 0.240 0.000
S01.8 Open wound of other parts of head
0.760 0.240 0.000
I77 Other disorders of arteries and arterioles
0.758 0.242 0.000
M54.4 Lumbago with sciatica
0.756 0.244 0.000
Chapter XI Diseases of the digestive system
0.756 0.244 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.756 0.244 0.000
M54.55 Low back pain (Thoracolumbar region)
0.755 0.245 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.755 0.245 0.000
Y85 Sequelae of transport accidents
0.755 0.245 0.000
I27 Other pulmonary heart diseases
0.754 0.246 0.000
S00.3 Superficial injury of nose
0.754 0.246 0.000
T65 Toxic effect of other and unspecified substances
0.753 0.247 0.000
K76 Other diseases of liver
0.752 0.248 0.000
X60-X84 Intentional self-harm
0.750 0.250 0.000
S01.9 Open wound of head, part unspecified
0.750 0.250 0.000
M24.0 Loose body in joint
0.749 0.251 0.000
S00.0 Superficial injury of scalp
0.748 0.252 0.000
I69 Sequelae of cerebrovascular disease
0.748 0.252 0.000
M47 Spondylosis
0.747 0.253 0.000
T82.1 Mechanical complication of cardiac electronic device
0.744 0.256 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.744 0.256 0.000
I05-I09 Chronic rheumatic heart diseases
0.743 0.257 0.000
F81 Specific developmental disorders of scholastic skills
0.742 0.258 0.000
M00-M03 Infectious arthropathies
0.740 0.259 0.000
T87 Complications peculiar to reattachment and amputation
0.740 0.260 0.000
S09.8 Other specified injuries of head
0.740 0.260 0.000
Y00-Y09 Assault
0.739 0.261 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.739 0.261 0.000
E66.9 Obesity, unspecified
0.738 0.262 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.737 0.263 0.000
F43.2 Adjustment disorders
0.736 0.263 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.735 0.265 0.000
M34 Systemic sclerosis
0.735 0.265 0.000
I60 Subarachnoid haemorrhage
0.733 0.267 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.733 0.267 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.732 0.268 0.000
M60-M63 Disorders of muscles
0.731 0.269 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.730 0.270 0.000
V40-V49 Car occupant injured in transport accident
0.730 0.270 0.000
K70 Alcoholic liver disease
0.729 0.271 0.000
S20-S29 Injuries to the thorax
0.728 0.272 0.000
S70 Superficial injury of hip and thigh
0.727 0.273 0.000
M23.9 Internal derangement of knee, unspecified
0.725 0.275 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.724 0.275 0.000
S06.8 Other intracranial injuries
0.723 0.277 0.000
S00.7 Multiple superficial injuries of head
0.722 0.278 0.000
M48 Other spondylopathies
0.721 0.279 0.000
G90-G99 Other disorders of the nervous system
0.721 0.279 0.000
Chapter I Certain infectious and parasitic diseases
0.721 0.279 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.720 0.280 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.720 0.280 0.000
T93 Sequelae of injuries of lower limb
0.718 0.282 0.000
H93 Other disorders of ear, not elsewhere classified
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
S08 Traumatic amputation of part of head
0.717 0.283 0.000
S07 Crushing injury of head
0.717 0.283 0.000
S04 Injury of cranial nerves
0.717 0.283 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.717 0.283 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.716 0.284 0.000
M54.19 Radiculopathy (Site unspecified)
0.716 0.284 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.716 0.284 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.716 0.284 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.716 0.284 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.716 0.284 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.716 0.284 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.716 0.284 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.716 0.284 0.000
F10.9 Unspecified mental and behavioural disorder
0.715 0.284 0.000
F10.8 Other mental and behavioural disorders
0.715 0.284 0.000
F10.7 Residual and late-onset psychotic disorder
0.715 0.284 0.000
F10.6 Amnesic syndrome
0.715 0.284 0.000
F10.5 Psychotic disorder
0.715 0.284 0.000
H81 Disorders of vestibular function
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.285 0.000
Y10-Y34 Event of undetermined intent
0.714 0.285 0.000
X85-X99 Assault
0.714 0.285 0.000
X30-X39 Exposure to forces of nature
0.714 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.285 0.000
X10-X19 Contact with heat and hot substances
0.714 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.285 0.000
W75-W84 Other accidental threats to breathing
0.714 0.285 0.000
W65-W74 Accidental drowning and submersion
0.714 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.285 0.000
V95-V97 Air and space transport accidents
0.714 0.285 0.000
V90-V94 Water transport accidents
0.714 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.285 0.000
I73.9 Peripheral vascular disease, unspecified
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.714 0.286 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.714 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
T36 Poisoning by systemic antibiotics
0.714 0.286 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.713 0.286 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.714 0.286 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.713 0.287 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.712 0.288 0.000
M25 Other joint disorders, not elsewhere classified
0.712 0.288 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.712 0.288 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.710 0.290 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.710 0.290 0.000
M32 Systemic lupus erythematosus
0.710 0.290 0.000
M30 Polyarteritis nodosa and related conditions
0.710 0.290 0.000
H83 Other diseases of inner ear
0.707 0.293 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.707 0.293 0.000
V80-V89 Other land transport accidents
0.706 0.294 0.000
M21.2 Flexion deformity
0.705 0.295 0.000
T66-T78 Other and unspecified effects of external causes
0.705 0.295 0.000
S06.00 Concussion (without open intracranial wound)
0.705 0.295 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.704 0.296 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.704 0.296 0.000
T39.4 Antirheumatics, not elsewhere classified
0.704 0.296 0.000
T39.2 Pyrazolone derivatives
0.704 0.296 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.703 0.297 0.000
E53 Deficiency of other B group vitamins
0.702 0.298 0.000
D68 Other coagulation defects
0.702 0.298 0.000
D80-D89 Certain disorders involving the immune mechanism
0.701 0.299 0.000
Y52 Agents primarily affecting the cardiovascular system
0.701 0.299 0.000
F25 Schizoaffective disorders
0.700 0.300 0.000
M54.8 Other dorsalgia
0.699 0.300 0.000
M54.0 Panniculitis affecting regions of neck and back
0.699 0.300 0.000
T82.3 Mechanical complication of other vascular grafts
0.698 0.302 0.000
E55 Vitamin D deficiency
0.698 0.302 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.698 0.302 0.000
M54.50 Low back pain (Multiple sites in spine)
0.697 0.303 0.000
H71 Cholesteatoma of middle ear
0.697 0.303 0.000
K76.9 Liver disease, unspecified
0.696 0.304 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.696 0.304 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.695 0.305 0.000
H69 Other disorders of Eustachian tube
0.695 0.305 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.694 0.306 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.694 0.306 0.000
H72 Perforation of tympanic membrane
0.694 0.306 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.693 0.307 0.000
M23.1 Discoid meniscus (congenital)
0.693 0.307 0.000
K76.6 Portal hypertension
0.692 0.308 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.692 0.308 0.000
G12 Spinal muscular atrophy and related syndromes
0.692 0.308 0.000
M65-M68 Disorders of synovium and tendon
0.691 0.309 0.000
Q21 Congenital malformations of cardiac septa
0.690 0.310 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.686 0.314 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.686 0.314 0.000
S00.5 Superficial injury of lip and oral cavity
0.685 0.315 0.000
S00.4 Superficial injury of ear
0.685 0.315 0.000
M24.1 Other articular cartilage disorders
0.685 0.315 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.684 0.316 0.000
X45 Accidental poisoning by and exposure to alcohol
0.684 0.316 0.000
S06.9 Intracranial injury, unspecified
0.684 0.316 0.000
S06.7 Intracranial injury with prolonged coma
0.684 0.316 0.000
S06.4 Epidural haemorrhage
0.684 0.316 0.000
S06.1 Traumatic cerebral oedema
0.684 0.316 0.000
Y59 Other and unspecified vaccines and biological substances
0.684 0.316 0.000
Y58 Bacterial vaccines
0.684 0.316 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.684 0.316 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.684 0.316 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.684 0.316 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.684 0.316 0.000
Y48 Anaesthetics and therapeutic gases
0.684 0.316 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.684 0.316 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.684 0.316 0.000
M91-M94 Chondropathies
0.683 0.317 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.683 0.317 0.000
S14 Injury of nerves and spinal cord at neck level
0.682 0.318 0.000
Y57 Other and unspecified drugs and medicaments
0.681 0.319 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.681 0.319 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.681 0.319 0.000
S00.8 Superficial injury of other parts of head
0.680 0.320 0.000
F23 Acute and transient psychotic disorders
0.680 0.320 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.679 0.321 0.000
I26 Pulmonary embolism
0.679 0.321 0.000
H93.1 Tinnitus
0.679 0.321 0.000
S06.2 Diffuse brain injury
0.678 0.322 0.000
S02.1 Fracture of base of skull
0.676 0.324 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.676 0.324 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.676 0.324 0.000
M35 Other systemic involvement of connective tissue
0.676 0.324 0.000
T14 Injury of unspecified body region
0.676 0.324 0.000
M54.2 Cervicalgia
0.675 0.325 0.000
S64 Injury of nerves at wrist and hand level
0.675 0.325 0.000
F20 Schizophrenia
0.674 0.326 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.674 0.326 0.000
B35-B49 Mycoses
0.674 0.326 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.674 0.326 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.672 0.328 0.000
T81 Complications of procedures, not elsewhere classified
0.672 0.328 0.000
M24.9 Joint derangement, unspecified
0.671 0.328 0.000
M24.7 Protrusio acetabuli
0.671 0.328 0.000
M24.5 Contracture of joint
0.671 0.328 0.000
M24.2 Disorder of ligament
0.671 0.328 0.000
I28 Other diseases of pulmonary vessels
0.671 0.329 0.000
F31.9 Bipolar affective disorder, unspecified
0.671 0.329 0.000
T63 Toxic effect of contact with venomous animals
0.670 0.330 0.000
T62 Toxic effect of other noxious substances eaten as food
0.670 0.330 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.670 0.330 0.000
T60 Toxic effect of pesticides
0.670 0.330 0.000
T59 Toxic effect of other gases, fumes and vapours
0.670 0.330 0.000
T57 Toxic effect of other inorganic substances
0.670 0.330 0.000
T56 Toxic effect of metals
0.670 0.330 0.000
T54 Toxic effect of corrosive substances
0.670 0.330 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.670 0.330 0.000
T52 Toxic effect of organic solvents
0.670 0.330 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.670 0.330 0.000
T58 Toxic effect of carbon monoxide
0.670 0.330 0.000
T55 Toxic effect of soaps and detergents
0.670 0.330 0.000
M23.5 Chronic instability of knee
0.670 0.330 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.669 0.330 0.000
Q50-Q56 Congenital malformations of genital organs
0.669 0.331 0.000
T90 Sequelae of injuries of head
0.669 0.331 0.000
S01.3 Open wound of ear
0.668 0.332 0.000
T79-T79 Certain early complications of trauma
0.668 0.332 0.000
I72.4 Aneurysm of artery of lower extremity
0.668 0.332 0.000
F43.0 Acute stress reaction
0.667 0.333 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.667 0.333 0.000
M23.37 Other meniscus derangements-Capsular lig
0.666 0.334 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.666 0.334 0.000
I77.1 Stricture of artery
0.666 0.334 0.000
Chapter XXII Codes for special purposes
0.666 0.334 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.666 0.334 0.000
F81.9 Developmental disorder of scholastic skills, unspecified
0.665 0.335 0.000
S02.0 Fracture of vault of skull
0.665 0.335 0.000
M54.54 Low back pain-Thoracic
0.664 0.336 0.000
M54.53 Low back pain-Cervicothoracic
0.664 0.336 0.000
M54.52 Low back pain-Cervical
0.664 0.336 0.000
M54.51 Low back pain-Occipit-atl-axl
0.664 0.336 0.000
G20-G26 Extrapyramidal and movement disorders
0.663 0.337 0.000
S09.7 Multiple injuries of head
0.663 0.337 0.000
S09.2 Traumatic rupture of ear drum
0.663 0.337 0.000
S09.1 Injury of muscle and tendon of head
0.663 0.337 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.663 0.337 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.662 0.338 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.662 0.338 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.662 0.338 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.662 0.338 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.662 0.338 0.000
I00-I02 Acute rheumatic fever
0.661 0.338 0.000
T92 Sequelae of injuries of upper limb
0.661 0.339 0.000
T86 Failure and rejection of transplanted organs and tissues
0.661 0.339 0.000
Q80-Q89 Other congenital malformations
0.661 0.339 0.000
W18 Other fall on same level
0.660 0.340 0.000
M21.1 Varus deformity, not elsewhere classified
0.659 0.341 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.659 0.341 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.659 0.341 0.000
E65 Localised adiposity
0.658 0.342 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.657 0.343 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.657 0.343 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.656 0.344 0.000
S02.8 Fractures of other skull and facial bones
0.655 0.344 0.000
M21.0 Valgus deformity, not elsewhere classified
0.655 0.345 0.000
S51 Open wound of forearm
0.654 0.346 0.000
T42.4 Benzodiazepines
0.653 0.346 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.653 0.347 0.000
E61 Deficiency of other nutrient elements
0.653 0.347 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.652 0.348 0.000
K86 Other diseases of pancreas
0.652 0.348 0.000
M33.2 Polymyositis
0.652 0.348 0.000
F68 Other disorders of adult personality and behaviour
0.652 0.348 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.652 0.348 0.000
F65 Disorders of sexual preference
0.652 0.348 0.000
F64 Gender identity disorders
0.652 0.348 0.000
F63 Habit and impulse disorders
0.652 0.348 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.652 0.348 0.000
F69 Unspecified disorder of adult personality and behaviour
0.652 0.348 0.000
F61 Mixed and other personality disorders
0.652 0.348 0.000
F22 Persistent delusional disorders
0.652 0.348 0.000
Q35-Q37 Cleft lip and cleft palate
0.651 0.349 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.651 0.349 0.000
M80 Osteoporosis with pathological fracture
0.651 0.349 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.651 0.349 0.000
T91 Sequelae of injuries of neck and trunk
0.650 0.350 0.000
S02.4 Fracture of malar and maxillary bones
0.650 0.350 0.000
X59 Exposure to unspecified factor
0.649 0.351 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.649 0.351 0.000
T17 Foreign body in respiratory tract
0.648 0.352 0.000
G44 Other headache syndromes
0.648 0.352 0.000
I27.2 Other secondary pulmonary hypertension
0.648 0.352 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.647 0.353 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.647 0.353 0.000
F42 Obsessive-compulsive disorder
0.647 0.353 0.000
S92 Fracture of foot, except ankle
0.647 0.353 0.000
M21.3 Wrist or foot drop (acquired)
0.646 0.353 0.000
M54.12 Radiculopathy (Cervical region)
0.646 0.354 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.645 0.354 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.645 0.355 0.000
S78 Traumatic amputation of hip and thigh
0.645 0.355 0.000
S77 Crushing injury of hip and thigh
0.645 0.355 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.645 0.355 0.000
S75 Injury of blood vessels at hip and thigh level
0.645 0.355 0.000
S74 Injury of nerves at hip and thigh level
0.645 0.355 0.000
S71 Open wound of hip and thigh
0.645 0.355 0.000
M31.3 Wegener's granulomatosis
0.645 0.355 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.644 0.356 0.000
H81.0 Meniere's disease
0.644 0.356 0.000
F60.9 Personality disorder, unspecified
0.643 0.357 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.643 0.357 0.000
F41 Other anxiety disorders
0.643 0.357 0.000
K74 Fibrosis and cirrhosis of liver
0.643 0.357 0.000
T88.4 Failed or difficult intubation
0.642 0.358 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.641 0.359 0.000
S67 Crushing injury of wrist and hand
0.641 0.359 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.640 0.359 0.000
Y44 Agents primarily affecting blood constituents
0.640 0.360 0.000
S72.2 Subtrochanteric fracture
0.639 0.361 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.639 0.361 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.639 0.361 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.639 0.361 0.000
T42.3 Barbiturates
0.639 0.361 0.000
T42.2 Succinimides and oxazolidinediones
0.639 0.361 0.000
T42.1 Iminostilbenes
0.639 0.361 0.000
T42.0 Hydantoin derivatives
0.639 0.361 0.000
S72.1 Pertrochanteric fracture
0.638 0.362 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.638 0.362 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.638 0.362 0.000
Y86 Sequelae of other accidents
0.638 0.362 0.000
K76.8 Other specified diseases of liver
0.638 0.362 0.000
G12.2 Motor neuron disease
0.636 0.364 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.636 0.364 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.636 0.364 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.636 0.364 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.636 0.364 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.636 0.364 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.636 0.364 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.636 0.364 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.635 0.364 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.635 0.365 0.000
F48 Other neurotic disorders
0.635 0.365 0.000
F44 Dissociative [conversion] disorders
0.635 0.365 0.000
F99 Mental disorder, not otherwise specified
0.635 0.365 0.000
T23 Burn and corrosion of wrist and hand
0.634 0.365 0.000
G70-G73 Diseases of myoneural junction and muscle
0.634 0.365 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.634 0.366 0.000
Y45.8 Other analgesics and antipyretics
0.634 0.366 0.000
Y45.5 4-Aminophenol derivatives
0.634 0.366 0.000
Y45.4 Antirheumatics
0.634 0.366 0.000
Q23 Congenital malformations of aortic and mitral valves
0.633 0.367 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.633 0.367 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.633 0.367 0.000
M54.14 Radiculopathy (Thoracic region)
0.633 0.367 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.633 0.367 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.633 0.367 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.633 0.367 0.000
D86 Sarcoidosis
0.633 0.367 0.000
G93 Other disorders of brain
0.632 0.368 0.000
T51.9 Alcohol, unspecified
0.632 0.368 0.000
Q00-Q07 Congenital malformations of the nervous system
0.631 0.369 0.000
S19 Other and unspecified injuries of neck
0.631 0.369 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.631 0.369 0.000
T98 Sequelae of other and unspecified effects of external causes
0.629 0.370 0.000
T95 Sequelae of burns, corrosions and frostbite
0.629 0.370 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.629 0.370 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.629 0.370 0.000
Y40.7 Antifungal antibiotics, systemically used
0.629 0.371 0.000
Y40.6 Rifamycins
0.629 0.371 0.000
Y40.5 Aminoglycosides
0.629 0.371 0.000
Y40.4 Tetracyclines
0.629 0.371 0.000
Y40.3 Macrolides
0.629 0.371 0.000
Y40.2 Chloramphenicol group
0.629 0.371 0.000
M40-M43 Deforming dorsopathies
0.629 0.371 0.000
W13 Fall from, out of or through building or structure
0.629 0.371 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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