TreeWAS – Variant ID: rs116879316

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter X Diseases of the respiratory system	0.999	0.001
J30-J39 Other diseases of upper respiratory tract	0.998	0.002
Chapter XIV Diseases of the genitourinary system	0.998	0.002
M20-M25 Other joint disorders	0.998	0.002
Chapter XXI Factors influencing health status and contact with health services	0.995	0.005
J34 Other disorders of nose and nasal sinuses	0.991	0.009
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.990	0.010
M50-M54 Other dorsopathies	0.987	0.013
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.986	0.014
Chapter XII Diseases of the skin and subcutaneous tissue	0.984	0.016
M54 Dorsalgia	0.980	0.020
Z92 Personal history of medical treatment	0.979	0.021
Z92.2 Personal history of long-term (current) use of other medicaments	0.975	0.025
Chapter VI Diseases of the nervous system	0.973	0.027
Z91 Personal history of risk-factors, not elsewhere classified	0.970	0.030
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.969	0.031
L80-L99 Other disorders of the skin and subcutaneous tissue	0.967	0.033
N25-N29 Other disorders of kidney and ureter	0.964	0.036
M54.5 Low back pain	0.962	0.038
J34.3 Hypertrophy of nasal turbinates	0.960	0.040
M25 Other joint disorders, not elsewhere classified	0.959	0.041
N60-N64 Disorders of breast	0.959	0.041
M80-M85 Disorders of bone density and structure	0.957	0.043
Z80 Family history of malignant neoplasm	0.957	0.043
M45-M49 Spondylopathies	0.952	0.048
Chapter II Neoplasms	0.943	0.057
N28 Other disorders of kidney and ureter, not elsewhere classified	0.939	0.061
M20 Acquired deformities of fingers and toes	0.939	0.061
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.938	0.062
N10-N16 Renal tubulo-interstitial diseases	0.936	0.064
Z91.6 Personal history of other physical trauma	0.936	0.064
N99-N99 Other disorders of the genitourinary system	0.932	0.068
C43-C44 Melanoma and other malignant neoplasms of skin	0.922	0.078
L82 Seborrhoeic keratosis	0.920	0.080
M81 Osteoporosis without pathological fracture	0.916	0.084
N70-N77 Inflammatory diseases of female pelvic organs	0.915	0.085
D37-D48 Neoplasms of uncertain or unknown behaviour	0.914	0.086
Z97 Presence of other devices	0.904	0.096
Z80.0 Family history of malignant neoplasm of digestive organs	0.899	0.101
C43 Malignant melanoma of skin	0.899	0.101
Chapter XI Diseases of the digestive system	0.899	0.101
M25.7 Osteophyte	0.897	0.103
J34.2 Deviated nasal septum	0.897	0.103
M54.59 Low back pain (Site unspecified)	0.896	0.104
N62 Hypertrophy of breast	0.895	0.105
J40-J47 Chronic lower respiratory diseases	0.891	0.109
M54.57 Low back pain (Lumbosacral region)	0.891	0.109
N63 Unspecified lump in breast	0.889	0.111
M81.9 Osteoporosis, unspecified	0.887	0.113
N28.9 Disorder of kidney and ureter, unspecified	0.887	0.113
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.885	0.115
C43.5 Malignant melanoma of trunk	0.885	0.115
Chapter VIII Diseases of the ear and mastoid process	0.885	0.115
Z80.9 Family history of malignant neoplasm, unspecified	0.881	0.119
Z70-Z76 Persons encountering health services in other circumstances	0.880	0.120
D68 Other coagulation defects	0.877	0.123
K70-K77 Diseases of liver	0.876	0.124
Z85 Personal history of malignant neoplasm	0.875	0.125
M81.99 Osteoporosis, unspecified (Site unspecified)	0.869	0.131
M24 Other specific joint derangements	0.869	0.131
D70-D77 Other diseases of blood and blood-forming organs	0.861	0.139
G80-G83 Cerebral palsy and other paralytic syndromes	0.860	0.140
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.857	0.143
M45 Ankylosing spondylitis	0.856	0.144
T66-T78 Other and unspecified effects of external causes	0.855	0.145
M21 Other acquired deformities of limbs	0.851	0.149
J30 Vasomotor and allergic rhinitis	0.850	0.150
Z92.1 Personal history of long-term (current) use of anticoagulants	0.847	0.153
M20.4 Other hammer toe(s) (acquired)	0.846	0.154
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.846	0.154
J32 Chronic sinusitis	0.845	0.155
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.843	0.157
L40-L45 Papulosquamous disorders	0.842	0.158
M20.6 Acquired deformity of toe(s), unspecified	0.842	0.158
J39 Other diseases of upper respiratory tract	0.840	0.160
Z83 Family history of other specific disorders	0.838	0.162
M25.76 Osteophyte (Lower leg)	0.835	0.165
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.834	0.166
Z85.3 Personal history of malignant neoplasm of breast	0.834	0.166
Z91.5 Personal history of self-harm	0.831	0.169
M47 Spondylosis	0.830	0.170
Z40-Z54 Persons encountering health services for specific procedures and health care	0.830	0.170
L92 Granulomatous disorders of skin and subcutaneous tissue	0.829	0.171
G50-G59 Nerve, nerve root and plexus disorders	0.828	0.172
M25.8 Other specified joint disorders	0.827	0.173
L20-L30 Dermatitis and eczema	0.825	0.175
L91 Hypertrophic disorders of skin	0.823	0.177
K76 Other diseases of liver	0.823	0.177
J44 Other chronic obstructive pulmonary disease	0.822	0.178
N10 Acute tubulo-interstitial nephritis	0.821	0.179
J95-J99 Other diseases of the respiratory system	0.821	0.179
Z97.8 Presence of other specified devices	0.818	0.182
M54.3 Sciatica	0.818	0.182
C50-C50 Malignant neoplasm of breast	0.818	0.182
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.817	0.183
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.816	0.184
J34.0 Abscess, furuncle and carbuncle of nose	0.815	0.185
S80-S89 Injuries to the knee and lower leg	0.815	0.185
D80-D89 Certain disorders involving the immune mechanism	0.812	0.188
N28.8 Other specified disorders of kidney and ureter	0.810	0.190
J33 Nasal polyp	0.807	0.193
L00-L08 Infections of the skin and subcutaneous tissue	0.806	0.194
N99.3 Prolapse of vaginal vault after hysterectomy	0.804	0.196
J34.1 Cyst and mucocele of nose and nasal sinus	0.802	0.197
Z47 Other orthopaedic follow-up care	0.801	0.199
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.801	0.199
M31 Other necrotising vasculopathies	0.801	0.199
M05-M14 Inflammatory polyarthropathies	0.798	0.202
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.795	0.205
N30-N39 Other diseases of urinary system	0.794	0.206
D69 Purpura and other haemorrhagic conditions	0.793	0.207
Z72 Problems related to lifestyle	0.788	0.212
M54.9 Dorsalgia, unspecified	0.787	0.212
M20.5 Other deformities of toe(s) (acquired)	0.786	0.214
Z80.4 Family history of malignant neoplasm of genital organs	0.785	0.215
L81 Other disorders of pigmentation	0.784	0.215
Z90 Acquired absence of organs, not elsewhere classified	0.783	0.217
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.782	0.218
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.781	0.219
J80-J84 Other respiratory diseases principally affecting the interstitium	0.779	0.221
J45 Asthma	0.779	0.221
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.778	0.221
L40 Psoriasis	0.778	0.222
G40-G47 Episodic and paroxysmal disorders	0.778	0.222
L97 Ulcer of lower limb, not elsewhere classified	0.777	0.223
G70-G73 Diseases of myoneural junction and muscle	0.775	0.225
Z92.0 Personal history of contraception	0.774	0.226
T78 Adverse effects, not elsewhere classified	0.773	0.227
D68.8 Other specified coagulation defects	0.773	0.227
Z97.4 Presence of external hearing-aid	0.772	0.228
M91-M94 Chondropathies	0.771	0.229
M23 Internal derangement of knee	0.771	0.229
Z90.1 Acquired absence of breast(s)	0.768	0.232
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.768	0.232
N32 Other disorders of bladder	0.768	0.232
D55-D59 Haemolytic anaemias	0.766	0.234
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.764	0.236
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.763	0.237
N73 Other female pelvic inflammatory diseases	0.763	0.237
Z72.1 Alcohol use	0.762	0.238
M25.4 Effusion of joint	0.762	0.238
J60-J70 Lung diseases due to external agents	0.761	0.239
M54.4 Lumbago with sciatica	0.759	0.241
N28.1 Cyst of kidney, acquired	0.758	0.242
T36-T50 Poisoning by drugs, medicaments and biological substances	0.758	0.242
G00-G09 Inflammatory diseases of the central nervous system	0.758	0.242
L02 Cutaneous abscess, furuncle and carbuncle	0.756	0.244
K50-K52 Noninfective enteritis and colitis	0.756	0.244
C44 Other malignant neoplasms of skin	0.755	0.245
M80 Osteoporosis with pathological fracture	0.754	0.246
K40-K46 Hernia	0.754	0.246
M24.1 Other articular cartilage disorders	0.752	0.248
M45.X9 Ankylosing spondylitis (Site unspecified)	0.749	0.251
K75 Other inflammatory liver diseases	0.748	0.252
M48 Other spondylopathies	0.748	0.252
N32.0 Bladder-neck obstruction	0.748	0.252
D60-D64 Aplastic and other anaemias	0.747	0.253
M20.1 Hallux valgus (acquired)	0.747	0.253
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.746	0.254
H65-H75 Diseases of middle ear and mastoid	0.746	0.254
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.746	0.254
Chapter IX Diseases of the circulatory system	0.746	0.254
M86-M90 Other osteopathies	0.742	0.258
M54.39 Sciatica (Site unspecified)	0.742	0.258
K74 Fibrosis and cirrhosis of liver	0.742	0.258
D37.4 Colon	0.741	0.259
M54.2 Cervicalgia	0.741	0.259
M53 Other dorsopathies, not elsewhere classified	0.741	0.259
J39.2 Other diseases of pharynx	0.740	0.260
M47.9 Spondylosis, unspecified	0.740	0.260
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.738	0.262
M00-M03 Infectious arthropathies	0.738	0.262
G57 Mononeuropathies of lower limb	0.738	0.262
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.737	0.263
D73 Diseases of spleen	0.736	0.264
C43.9 Malignant melanoma of skin, unspecified	0.733	0.266
Chapter XV Pregnancy, childbirth and the puerperium	0.733	0.267
G20-G26 Extrapyramidal and movement disorders	0.733	0.267
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.732	0.268
M25.86 Other specified joint disorders (Lower leg)	0.732	0.268
L83 Acanthosis nigricans	0.731	0.269
N70 Salpingitis and oophoritis	0.729	0.271
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.729	0.271
C50 Malignant neoplasm of breast	0.728	0.272
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.728	0.272
K76.0 Fatty (change of) liver, not elsewhere classified	0.728	0.272
L90 Atrophic disorders of skin	0.727	0.273
M25.3 Other instability of joint	0.726	0.274
S10-S19 Injuries to the neck	0.726	0.274
H80-H83 Diseases of inner ear	0.726	0.274
D68.9 Coagulation defect, unspecified	0.726	0.274
J45.9 Asthma, unspecified	0.725	0.275
M35 Other systemic involvement of connective tissue	0.724	0.276
M54.1 Radiculopathy	0.724	0.276
D75 Other diseases of blood and blood-forming organs	0.722	0.278
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.721	0.279
T79-T79 Certain early complications of trauma	0.721	0.279
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.721	0.279
G81 Hemiplegia	0.721	0.279
G35-G37 Demyelinating diseases of the central nervous system	0.720	0.280
N72 Inflammatory disease of cervix uteri	0.718	0.282
M34 Systemic sclerosis	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
Z98 Other postsurgical states	0.716	0.284
J37 Chronic laryngitis and laryngotracheitis	0.716	0.284
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.715	0.284
M33 Dermatopolymyositis	0.715	0.284
M32 Systemic lupus erythematosus	0.715	0.284
M30 Polyarteritis nodosa and related conditions	0.715	0.284
Chapter VII Diseases of the eye and adnexa	0.715	0.285
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.715	0.285
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.715	0.285
J30.1 Allergic rhinitis due to pollen	0.714	0.286
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.714	0.286
S90-S99 Injuries to the ankle and foot	0.713	0.287
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.713	0.287
I30-I52 Other forms of heart disease	0.713	0.287
L91.8 Other hypertrophic disorders of skin	0.712	0.288
Z92.8 Personal history of other medical treatment	0.712	0.288
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.711	0.289
J36 Peritonsillar abscess	0.710	0.290
Z84 Family history of other conditions	0.710	0.290
Z81 Family history of mental and behavioural disorders	0.710	0.290
D37.5 Rectum	0.707	0.293
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.707	0.293
S00-S09 Injuries to the head	0.707	0.293
K81 Cholecystitis	0.706	0.294
Z41 Procedures for purposes other than remedying health state	0.706	0.294
M54.6 Pain in thoracic spine	0.705	0.294
L10-L14 Bullous disorders	0.705	0.295
K50 Crohn's disease [regional enteritis]	0.704	0.296
D68.2 Hereditary deficiency of other clotting factors	0.704	0.296
Z83.7 Family history of diseases of the digestive system	0.704	0.296
M54.8 Other dorsalgia	0.703	0.297
M54.0 Panniculitis affecting regions of neck and back	0.703	0.297
G30-G32 Other degenerative diseases of the nervous system	0.703	0.297
N76 Other inflammation of vagina and vulva	0.703	0.297
N99.5 Malfunction of external stoma of urinary tract	0.702	0.298
Z89 Acquired absence of limb	0.702	0.298
Z92.9 Personal history of medical treatment, unspecified	0.702	0.298
Z92.5 Personal history of rehabilitation measures	0.702	0.298
M84 Disorders of continuity of bone	0.702	0.298
Chapter XX External causes of morbidity and mortality	0.702	0.298
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.701	0.299
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.701	0.299
M50 Cervical disk disorders	0.700	0.300
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.700	0.300
T78.3 Angioneurotic oedema	0.698	0.302
H90-H95 Other disorders of ear	0.698	0.302
S20-S29 Injuries to the thorax	0.697	0.302
G90-G99 Other disorders of the nervous system	0.697	0.303
L40.0 Psoriasis vulgaris	0.696	0.304
J42 Unspecified chronic bronchitis	0.696	0.304
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.695	0.305
Z91.7 Personal history of female genital mutilation	0.695	0.305
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.695	0.305
Z91.3 Personal history of unhealthy sleep-wake schedule	0.695	0.305
Z91.2 Personal history of poor personal hygiene	0.695	0.305
T33-T35 Frostbite	0.695	0.305
T26-T28 Burns and corrosions confined to eye and internal organs	0.695	0.305
T20-T25 Burns and corrosions of external body surface, specified by site	0.695	0.305
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.695	0.305
T00-T07 Injuries involving multiple body regions	0.695	0.305
J32.2 Chronic ethmoidal sinusitis	0.695	0.305
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.693	0.307
L95 Vasculitis limited to skin, not elsewhere classified	0.693	0.307
L94 Other localised connective tissue disorders	0.693	0.307
L93 Lupus erythematosus	0.693	0.307
L87 Transepidermal elimination disorders	0.693	0.307
L88 Pyoderma gangrenosum	0.693	0.307
L86 Keratoderma in diseases classified elsewhere	0.693	0.307
L80 Vitiligo	0.693	0.307
K76.9 Liver disease, unspecified	0.692	0.308
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.691	0.309
N27 Small kidney of unknown cause	0.691	0.309
N25 Disorders resulting from impaired renal tubular function	0.691	0.309
N26 Unspecified contracted kidney	0.691	0.309
N99.0 Postprocedural renal failure	0.691	0.309
G47 Sleep disorders	0.691	0.309
K41 Femoral hernia	0.690	0.309
M65-M68 Disorders of synovium and tendon	0.690	0.310
D86 Sarcoidosis	0.690	0.310
M21.1 Varus deformity, not elsewhere classified	0.690	0.310
M54.55 Low back pain (Thoracolumbar region)	0.690	0.310
M54.54 Low back pain-Thoracic	0.690	0.310
M54.53 Low back pain-Cervicothoracic	0.690	0.310
M54.52 Low back pain-Cervical	0.690	0.310
M54.51 Low back pain-Occipit-atl-axl	0.690	0.310
M54.50 Low back pain (Multiple sites in spine)	0.690	0.310
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.689	0.311
M25.9 Joint disorder, unspecified	0.687	0.312
M25.6 Stiffness of joint, not elsewhere classified	0.687	0.312
M25.2 Flail joint	0.687	0.312
M25.1 Fistula of joint	0.687	0.312
M25.0 Haemarthrosis	0.687	0.312
S50-S59 Injuries to the elbow and forearm	0.687	0.313
M21.4 Flat foot [pes planus] (acquired)	0.686	0.314
M47.99 Spondylosis, unspecified (Site unspecified)	0.686	0.314
M83 Adult osteomalacia	0.686	0.314
M82 Osteoporosis in diseases classified elsewhere	0.686	0.314
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.686	0.314
Z80.6 Family history of leukaemia	0.686	0.314
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.686	0.314
M25.74 Osteophyte (Hand)	0.686	0.314
J31.0 Chronic rhinitis	0.685	0.315
T90 Sequelae of injuries of head	0.684	0.316
T92 Sequelae of injuries of upper limb	0.683	0.317
M49 Spondylopathies in diseases classified elsewhere	0.683	0.317
Chapter XXII Codes for special purposes	0.683	0.317
L92.0 Granuloma annulare	0.682	0.318
D38.1 Trachea, bronchus and lung	0.682	0.318
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.681	0.319
M25.78 Osteophyte (Other)	0.681	0.319
N75 Diseases of Bartholin's gland	0.681	0.319
M54.99 Dorsalgia, unspecified (Site unspecified)	0.679	0.320
N64 Other disorders of breast	0.679	0.321
G82 Paraplegia and tetraplegia	0.679	0.321
G57.6 Lesion of plantar nerve	0.679	0.321
M23.2 Derangement of meniscus due to old tear or injury	0.678	0.322
Z42 Follow-up care involving plastic surgery	0.678	0.322
O60-O75 Complications of labour and delivery	0.678	0.322
C44.5 Skin of trunk	0.677	0.323
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.676	0.324
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.676	0.324
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.676	0.324
C40-C41 Malignant neoplasms of bone and articular cartilage	0.676	0.324
N99.8 Other postprocedural disorders of genito-urinary system	0.675	0.324
J44.8 Other specified chronic obstructive pulmonary disease	0.674	0.326
I49 Other cardiac arrhythmias	0.674	0.326
J33.9 Nasal polyp, unspecified	0.674	0.326
N28.0 Ischaemia and infarction of kidney	0.674	0.326
D67 Hereditary factor IX deficiency	0.673	0.327
D66 Hereditary factor VIII deficiency	0.673	0.327
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.673	0.327
M24.4 Recurrent dislocation and subluxation of joint	0.673	0.327
M25.77 Osteophyte (Ankle and foot)	0.672	0.328
M46 Other inflammatory spondylopathies	0.672	0.328
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.671	0.328
N15 Other renal tubulo-interstitial diseases	0.671	0.328
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.671	0.328
N11 Chronic tubulo-interstitial nephritis	0.671	0.328
T86 Failure and rejection of transplanted organs and tissues	0.671	0.329
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.671	0.329
L28 Lichen simplex chronicus and prurigo	0.671	0.329
G83 Other paralytic syndromes	0.670	0.330
M24.16 Other articular cartilage disorders (Lower leg)	0.669	0.331
Z43 Attention to artificial openings	0.668	0.332
Chapter I Certain infectious and parasitic diseases	0.667	0.333
M85 Other disorders of bone density and structure	0.667	0.333
Chapter V Mental and behavioural disorders	0.667	0.333
Q50-Q56 Congenital malformations of genital organs	0.664	0.336
I60-I69 Cerebrovascular diseases	0.664	0.336
J95 Postprocedural respiratory disorders, not elsewhere classified	0.663	0.337
J33.8 Other polyp of sinus	0.663	0.337
J30.4 Allergic rhinitis, unspecified	0.663	0.337
M81.90 Osteoporosis, unspecified (Multiple sites)	0.663	0.337
G47.9 Sleep disorder, unspecified	0.663	0.337
D50-D53 Nutritional anaemias	0.662	0.337
N99.4 Postprocedural pelvic peritoneal adhesions	0.662	0.338
L85 Other epidermal thickening	0.662	0.338
M31.6 Other giant cell arteritis	0.662	0.338
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.662	0.338
L84 Corns and callosities	0.661	0.338
J32.8 Other chronic sinusitis	0.661	0.339
Z74 Problems related to care-provider dependency	0.661	0.339
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.661	0.339
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.661	0.339
L27 Dermatitis due to substances taken internally	0.660	0.340
S82 Fracture of lower leg, including ankle	0.660	0.340
K35-K38 Diseases of appendix	0.660	0.340
G43 Migraine	0.659	0.341
J86 Pyothorax	0.659	0.341
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.658	0.342
M81.8 Other osteoporosis	0.657	0.343
M81.6 Localised osteoporosis [Lequesne]	0.657	0.343
M81.5 Idiopathic osteoporosis	0.657	0.343
M81.4 Drug-induced osteoporosis	0.657	0.343
M81.3 Postsurgical malabsorption osteoporosis	0.657	0.343
M81.2 Osteoporosis of disuse	0.657	0.343
M81.1 Postoophorectomy osteoporosis	0.657	0.343
M81.0 Postmenopausal osteoporosis	0.657	0.343
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.656	0.344
I47 Paroxysmal tachycardia	0.656	0.344
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.655	0.345
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.655	0.345
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.655	0.345
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.655	0.345
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.655	0.345
D47.3 Essential (haemorrhagic) thrombocythaemia	0.655	0.345
D37.7 Other digestive organs	0.654	0.345
L81.9 Disorder of pigmentation, unspecified	0.653	0.347
I05-I09 Chronic rheumatic heart diseases	0.653	0.347
K81.9 Cholecystitis, unspecified	0.653	0.347
J32.0 Chronic maxillary sinusitis	0.652	0.348
I49.9 Cardiac arrhythmia, unspecified	0.651	0.349
K76.6 Portal hypertension	0.651	0.349
J32.4 Chronic pansinusitis	0.650	0.350
N73.9 Female pelvic inflammatory disease, unspecified	0.650	0.350
D72 Other disorders of white blood cells	0.650	0.350
K72 Hepatic failure, not elsewhere classified	0.650	0.350
J34.8 Other specified disorders of nose and nasal sinuses	0.650	0.350
M20.3 Other deformity of hallux (acquired)	0.649	0.351
M21.6 Other acquired deformities of ankle and foot	0.648	0.352
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.648	0.352
Z97.3 Presence of spectacles and contact lenses	0.648	0.352
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.648	0.352
Z97.1 Presence of artificial limb (complete)(partial)	0.648	0.352
Z97.0 Presence of artificial eye	0.648	0.352
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.648	0.352
G58 Other mononeuropathies	0.647	0.353
D73.0 Hyposplenism	0.646	0.354
J40 Bronchitis, not specified as acute or chronic	0.646	0.354
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.646	0.354
G56 Mononeuropathies of upper limb	0.646	0.354
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.645	0.355
C43.8 Overlapping malignant melanoma of skin	0.644	0.355
C43.4 Malignant melanoma of scalp and neck	0.644	0.355
C43.2 Malignant melanoma of ear and external auricular canal	0.644	0.355
C43.1 Malignant melanoma of eyelid, including canthus	0.644	0.355
C43.0 Malignant melanoma of lip	0.644	0.355
Z80.5 Family history of malignant neoplasm of urinary tract	0.644	0.356
K65-K67 Diseases of peritoneum	0.644	0.356
M06 Other rheumatoid arthritis	0.644	0.356
M25.79 Osteophyte (Site unspecified)	0.643	0.357
M25.73 Osteophyte (Forearm)	0.643	0.357
M25.72 Osteophyte (Upper arm)	0.643	0.357
M25.71 Osteophyte (Shoulder region)	0.643	0.357
M25.70 Osteophyte (Multiple sites)	0.643	0.357
Z52 Donors of organs and tissues	0.643	0.357
T93 Sequelae of injuries of lower limb	0.642	0.358
D62 Acute posthaemorrhagic anaemia	0.641	0.359
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.641	0.359
Z80.8 Family history of malignant neoplasm of other organs or systems	0.640	0.360
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.640	0.360
J41 Simple and mucopurulent chronic bronchitis	0.639	0.361
O68 Labour and delivery complicated by foetal stress [distress]	0.639	0.361
C43.6 Malignant melanoma of upper limb, including shoulder	0.638	0.362
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.637	0.363
Z83.5 Family history of eye and ear disorders	0.636	0.364
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.636	0.364
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.636	0.364
M81.96 Osteoporosis, unspecified (Lower leg)	0.636	0.364
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.636	0.364
M81.94 Osteoporosis, unspecified (Hand)	0.636	0.364
M81.93 Osteoporosis, unspecified (Forearm)	0.636	0.364
M81.92 Osteoporosis, unspecified (Upper arm)	0.636	0.364
M81.91 Osteoporosis, unspecified (Shoulder region)	0.636	0.364
K42 Umbilical hernia	0.635	0.365
J38.4 Oedema of larynx	0.635	0.365
T78.4 Allergy, unspecified	0.635	0.365
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.634	0.365
N99.2 Postprocedural adhesions of vagina	0.634	0.365
N99.1 Postprocedural urethral stricture	0.634	0.365
Z98.1 Arthrodesis status	0.634	0.366
S80 Superficial injury of lower leg	0.633	0.367
H74 Other disorders of middle ear and mastoid	0.633	0.367
N71 Inflammatory disease of uterus, except cervix	0.632	0.368
J98 Other respiratory disorders	0.631	0.369
Z76 Persons encountering health services in other circumstances	0.631	0.369
Z73 Problems related to life-management difficulty	0.631	0.369
Z70 Counselling related to sexual attitude, behaviour and orientation	0.631	0.369
J00-J06 Acute upper respiratory infections	0.629	0.371
D68.6 Other Thrombophilia	0.629	0.371
D68.5 Primary Thrombophilia	0.629	0.371
D68.4 Acquired coagulation factor deficiency	0.629	0.371
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.629	0.371
D68.1 Hereditary factor XI deficiency	0.629	0.371
D68.0 Von Willebrand's disease	0.629	0.371
N70.9 Salpingitis and oophoritis, unspecified	0.628	0.372
K83 Other diseases of biliary tract	0.628	0.372
K77 Liver disorders in diseases classified elsewhere	0.628	0.372
K73 Chronic hepatitis, not elsewhere classified	0.628	0.372
K71 Toxic liver disease	0.628	0.372
Chapter IV Endocrine, nutritional and metabolic diseases	0.628	0.372
Z85.0 Personal history of malignant neoplasm of digestive organs	0.627	0.373
Z85.9 Personal history of malignant neoplasm, unspecified	0.627	0.373
T15-T19 Effects of foreign body entering through natural orifice	0.627	0.373
D69.5 Secondary thrombocytopenia	0.627	0.373
N32.1 Vesicointestinal fistula	0.626	0.373
I38 Endocarditis, valve unspecified	0.625	0.375
N00-N08 Glomerular diseases	0.624	0.375
T31 Burns classified according to extent of body surface involved	0.624	0.376
K75.4 Autoimmune hepatitis	0.623	0.377
M24.9 Joint derangement, unspecified	0.623	0.377
M24.8 Other specific joint derangements, not elsewhere classified	0.623	0.377
M24.7 Protrusio acetabuli	0.623	0.377
M24.6 Ankylosis of joint	0.623	0.377
M24.5 Contracture of joint	0.623	0.377
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.623	0.377
M24.2 Disorder of ligament	0.623	0.377
M24.0 Loose body in joint	0.623	0.377
T81 Complications of procedures, not elsewhere classified	0.623	0.377
M07 Psoriatic and enteropathic arthropathies	0.622	0.378
M47.2 Other spondylosis with radiculopathy	0.622	0.378
K74.3 Primary biliary cirrhosis	0.621	0.379
G81.9 Hemiplegia, unspecified	0.620	0.380
M35.0 Sicca syndrome [Sjogren]	0.620	0.380

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations