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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116916924
log Bayes Factor = 15.3017
Chromosome 11   position 48,269,422  (GRCh37) Explore rs116916924 on Ensembl!
Variant rs116916924 is part of Cluster X0063

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.998 0.002 0.000
M20-M25 Other joint disorders
0.996 0.004 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.994 0.006 0.000
M25 Other joint disorders, not elsewhere classified
0.990 0.010 0.000
M05-M14 Inflammatory polyarthropathies
0.989 0.011 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.979 0.021 0.000
M25.5 Pain in joint
0.978 0.022 0.000
M15-M19 Arthrosis
0.970 0.030 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.969 0.031 0.000
H30-H36 Disorders of choroid and retina
0.969 0.031 0.000
Z48 Other surgical follow-up care
0.966 0.034 0.000
M45-M49 Spondylopathies
0.959 0.041 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.953 0.047 0.000
Chapter XIV Diseases of the genitourinary system
0.950 0.050 0.000
O80-O84 Delivery
0.949 0.051 0.000
Chapter IX Diseases of the circulatory system
0.946 0.054 0.000
M19 Other arthrosis
0.939 0.061 0.000
M70-M79 Other soft tissue disorders
0.937 0.063 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.936 0.064 0.000
M13 Other arthritis
0.935 0.065 0.000
Chapter V Mental and behavioural disorders
0.934 0.066 0.000
M06 Other rheumatoid arthritis
0.928 0.072 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.922 0.078 0.000
M48 Other spondylopathies
0.920 0.080 0.000
O80 Single spontaneous delivery
0.918 0.082 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.918 0.082 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.917 0.083 0.000
G56 Mononeuropathies of upper limb
0.915 0.085 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.912 0.088 0.000
Z43 Attention to artificial openings
0.911 0.089 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.911 0.089 0.000
I60-I69 Cerebrovascular diseases
0.906 0.094 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.905 0.095 0.000
M19.9 Arthrosis, unspecified
0.905 0.095 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.904 0.096 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.904 0.096 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.904 0.096 0.000
M13.9 Arthritis, unspecified
0.897 0.103 0.000
F30-F39 Mood [affective] disorders
0.894 0.106 0.000
M48.0 Spinal stenosis
0.892 0.108 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.891 0.109 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.888 0.112 0.000
M06.9 Rheumatoid arthritis, unspecified
0.885 0.115 0.000
L60-L75 Disorders of skin appendages
0.884 0.116 0.000
N80 Endometriosis
0.877 0.123 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.876 0.124 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.876 0.124 0.000
O80.0 Spontaneous vertex delivery
0.872 0.128 0.000
M25.50 Pain in joint (Multiple sites)
0.871 0.129 0.000
N95 Menopausal and other perimenopausal disorders
0.871 0.129 0.000
O42 Premature rupture of membranes
0.870 0.130 0.000
M48.06 Spinal stenosis (Lumbar region)
0.867 0.133 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.865 0.135 0.000
H25-H28 Disorders of lens
0.864 0.136 0.000
Z48.9 Surgical follow-up care, unspecified
0.863 0.136 0.000
Z48.8 Other specified surgical follow-up care
0.863 0.137 0.000
Z42 Follow-up care involving plastic surgery
0.862 0.138 0.000
M35 Other systemic involvement of connective tissue
0.862 0.138 0.000
M25.57 Pain in joint (Ankle and foot)
0.860 0.140 0.000
H34 Retinal vascular occlusions
0.860 0.140 0.000
Z88.2 Personal history of allergy to sulphonamides
0.860 0.140 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.860 0.140 0.000
N80.0 Endometriosis of uterus
0.860 0.140 0.000
H35 Other retinal disorders
0.859 0.141 0.000
H52 Disorders of refraction and accommodation
0.858 0.142 0.000
M25.7 Osteophyte
0.856 0.144 0.000
N95.0 Postmenopausal bleeding
0.855 0.145 0.000
O36 Maternal care for other known or suspected foetal problems
0.854 0.146 0.000
G56.0 Carpal tunnel syndrome
0.849 0.151 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.847 0.153 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.847 0.153 0.000
G57 Mononeuropathies of lower limb
0.846 0.154 0.000
M20 Acquired deformities of fingers and toes
0.844 0.156 0.000
M79.6 Pain in limb
0.843 0.157 0.000
S40-S49 Injuries to the shoulder and upper arm
0.839 0.161 0.000
M80-M85 Disorders of bone density and structure
0.838 0.162 0.000
M25.51 Pain in joint (Shoulder region)
0.838 0.162 0.000
H40-H42 Glaucoma
0.837 0.163 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.836 0.164 0.000
Z37 Outcome of delivery
0.832 0.168 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.830 0.170 0.000
M79.8 Other specified soft tissue disorders
0.829 0.171 0.000
G90-G99 Other disorders of the nervous system
0.827 0.173 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.825 0.175 0.000
Z41 Procedures for purposes other than remedying health state
0.825 0.175 0.000
M40-M43 Deforming dorsopathies
0.825 0.175 0.000
S00-S09 Injuries to the head
0.824 0.176 0.000
M25.56 Pain in joint (Lower leg)
0.821 0.179 0.000
Z51 Other medical care
0.821 0.179 0.000
N30-N39 Other diseases of urinary system
0.818 0.182 0.000
Z04 Examination and observation for other reasons
0.815 0.185 0.000
F32 Depressive episode
0.814 0.186 0.000
Chapter VIII Diseases of the ear and mastoid process
0.813 0.187 0.000
M25.53 Pain in joint (Forearm)
0.813 0.187 0.000
Z88.0 Personal history of allergy to penicillin
0.810 0.190 0.000
O60-O75 Complications of labour and delivery
0.809 0.191 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.808 0.192 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.804 0.196 0.000
Z48.0 Attention to surgical dressings and sutures
0.801 0.199 0.000
N72 Inflammatory disease of cervix uteri
0.801 0.199 0.000
F31 Bipolar affective disorder
0.800 0.200 0.000
Z37.0 Single live birth
0.799 0.201 0.000
Z45 Adjustment and management of implanted device
0.799 0.201 0.000
Z87 Personal history of other diseases and conditions
0.798 0.202 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.796 0.204 0.000
M16 Coxarthrosis [arthrosis of hip]
0.795 0.205 0.000
O80.9 Single spontaneous delivery, unspecified
0.795 0.205 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.794 0.206 0.000
G58 Other mononeuropathies
0.792 0.208 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.789 0.211 0.000
M05 Seropositive rheumatoid arthritis
0.787 0.213 0.000
I78 Diseases of capillaries
0.784 0.216 0.000
S90-S99 Injuries to the ankle and foot
0.782 0.218 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.782 0.218 0.000
S20-S29 Injuries to the thorax
0.781 0.219 0.000
D80-D89 Certain disorders involving the immune mechanism
0.781 0.219 0.000
M45 Ankylosing spondylitis
0.780 0.220 0.000
L72.1 Trichilemmal cyst
0.777 0.223 0.000
H33 Retinal detachments and breaks
0.776 0.224 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.774 0.226 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.774 0.226 0.000
H36 Retinal disorders in diseases classified elsewhere
0.773 0.227 0.000
Chapter XI Diseases of the digestive system
0.773 0.227 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.772 0.228 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.771 0.229 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.771 0.229 0.000
M25.4 Effusion of joint
0.770 0.230 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.767 0.233 0.000
M19.0 Primary arthrosis of other joints
0.766 0.234 0.000
Z49 Care involving dialysis
0.766 0.234 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.765 0.235 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.765 0.235 0.000
G56.2 Lesion of ulnar nerve
0.764 0.236 0.000
S60-S69 Injuries to the wrist and hand
0.764 0.236 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.764 0.236 0.000
H52.1 Myopia
0.762 0.238 0.000
H21 Other disorders of iris and ciliary body
0.759 0.241 0.000
S80-S89 Injuries to the knee and lower leg
0.759 0.241 0.000
Z43.2 Attention to ileostomy
0.759 0.241 0.000
N87 Dysplasia of cervix uteri
0.759 0.241 0.000
G57.6 Lesion of plantar nerve
0.758 0.242 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.758 0.242 0.000
G70-G73 Diseases of myoneural junction and muscle
0.757 0.243 0.000
O36.8 Maternal care for other specified foetal problems
0.757 0.243 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.756 0.243 0.000
Chapter XXII Codes for special purposes
0.756 0.244 0.000
H53-H54 Visual disturbances and blindness
0.756 0.244 0.000
H35.3 Degeneration of macula and posterior pole
0.755 0.245 0.000
Z51.0 Radiotherapy session
0.754 0.246 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.752 0.248 0.000
H25 Senile cataract
0.751 0.249 0.000
Z97 Presence of other devices
0.749 0.251 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.749 0.251 0.000
M50-M54 Other dorsopathies
0.748 0.251 0.000
M21 Other acquired deformities of limbs
0.748 0.252 0.000
N73 Other female pelvic inflammatory diseases
0.746 0.254 0.000
I78.1 Naevus, nonneoplastic
0.746 0.254 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.746 0.254 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.745 0.255 0.000
H34.2 Other retinal artery occlusions
0.744 0.256 0.000
M13.93 Arthritis, unspecified (Forearm)
0.744 0.256 0.000
N36 Other disorders of urethra
0.744 0.256 0.000
H10-H13 Disorders of conjunctiva
0.743 0.257 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.743 0.257 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.743 0.257 0.000
H52.0 Hypermetropia
0.742 0.258 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.740 0.260 0.000
N99-N99 Other disorders of the genitourinary system
0.739 0.261 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.739 0.261 0.000
Z88.5 Personal history of allergy to narcotic agent
0.738 0.262 0.000
M22 Disorders of patella
0.737 0.263 0.000
Z86 Personal history of certain other diseases
0.737 0.263 0.000
Z04.8 Examination and observation for other specified reasons
0.736 0.264 0.000
H20 Iridocyclitis
0.736 0.264 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.735 0.265 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.735 0.265 0.000
Z80 Family history of malignant neoplasm
0.735 0.265 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.734 0.266 0.000
M11 Other crystal arthropathies
0.732 0.268 0.000
G50 Disorders of trigeminal nerve
0.731 0.268 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.730 0.270 0.000
Chapter XX External causes of morbidity and mortality
0.730 0.270 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.729 0.271 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.729 0.271 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.728 0.272 0.000
M19.98 Arthrosis, unspecified (Other)
0.728 0.272 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.727 0.273 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.727 0.273 0.000
Z43.3 Attention to colostomy
0.726 0.274 0.000
M35.0 Sicca syndrome [Sjogren]
0.725 0.275 0.000
Z98 Other postsurgical states
0.725 0.275 0.000
Z01.8 Other specified special examinations
0.724 0.276 0.000
H18 Other disorders of cornea
0.722 0.278 0.000
F32.9 Depressive episode, unspecified
0.722 0.278 0.000
I05-I09 Chronic rheumatic heart diseases
0.721 0.278 0.000
L73 Other follicular disorders
0.721 0.279 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.721 0.279 0.000
H40 Glaucoma
0.721 0.279 0.000
T66-T78 Other and unspecified effects of external causes
0.719 0.281 0.000
M79.66 Pain in limb (Lower leg)
0.719 0.281 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.718 0.282 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.717 0.282 0.000
Z50 Care involving use of rehabilitation procedures
0.717 0.283 0.000
I67 Other cerebrovascular diseases
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M86-M90 Other osteopathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H55-H59 Other disorders of eye and adnexa
0.716 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.716 0.284 0.000
Z54 Convalescence
0.716 0.284 0.000
Z52 Donors of organs and tissues
0.716 0.284 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.284 0.000
N85.0 Endometrial glandular hyperplasia
0.715 0.285 0.000
D55-D59 Haemolytic anaemias
0.714 0.285 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.714 0.286 0.000
M34 Systemic sclerosis
0.714 0.286 0.000
M33 Dermatopolymyositis
0.714 0.286 0.000
M32 Systemic lupus erythematosus
0.714 0.286 0.000
M30 Polyarteritis nodosa and related conditions
0.714 0.286 0.000
Z46 Fitting and adjustment of other devices
0.714 0.286 0.000
N00-N08 Glomerular diseases
0.713 0.287 0.000
M79.60 Pain in limb (Multiple sites)
0.713 0.287 0.000
O85-O92 Complications predominantly related to the puerperium
0.712 0.288 0.000
F31.9 Bipolar affective disorder, unspecified
0.711 0.289 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.711 0.289 0.000
M25.9 Joint disorder, unspecified
0.710 0.290 0.000
M25.8 Other specified joint disorders
0.710 0.290 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.710 0.290 0.000
M25.3 Other instability of joint
0.710 0.290 0.000
M25.2 Flail joint
0.710 0.290 0.000
M25.1 Fistula of joint
0.710 0.290 0.000
M25.0 Haemarthrosis
0.710 0.290 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.709 0.291 0.000
M14 Arthropathies in other diseases classified elsewhere
0.709 0.291 0.000
M12 Other specific arthropathies
0.709 0.291 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.709 0.291 0.000
M08 Juvenile arthritis
0.709 0.291 0.000
T79-T79 Certain early complications of trauma
0.708 0.292 0.000
T33-T35 Frostbite
0.708 0.292 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.708 0.292 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.708 0.292 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.708 0.292 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.708 0.292 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.708 0.292 0.000
T00-T07 Injuries involving multiple body regions
0.708 0.292 0.000
S10-S19 Injuries to the neck
0.708 0.292 0.000
N60-N64 Disorders of breast
0.708 0.292 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.708 0.292 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.707 0.292 0.000
M65-M68 Disorders of synovium and tendon
0.707 0.292 0.000
D60-D64 Aplastic and other anaemias
0.706 0.294 0.000
Z02 Examination and encounter for administrative purposes
0.706 0.294 0.000
M17 Gonarthrosis [arthrosis of knee]
0.705 0.295 0.000
M07 Psoriatic and enteropathic arthropathies
0.705 0.295 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.704 0.296 0.000
N97 Female infertility
0.704 0.296 0.000
M20.5 Other deformities of toe(s) (acquired)
0.704 0.296 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.704 0.296 0.000
M31 Other necrotising vasculopathies
0.703 0.296 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.703 0.297 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.702 0.298 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.702 0.298 0.000
M25.78 Osteophyte (Other)
0.702 0.298 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.701 0.299 0.000
M25.59 Pain in joint (Site unspecified)
0.701 0.299 0.000
M25.58 Pain in joint (Other)
0.701 0.299 0.000
M25.54 Pain in joint (Hand)
0.701 0.299 0.000
M25.52 Pain in joint (Upper arm)
0.701 0.299 0.000
M43 Other deforming dorsopathies
0.700 0.300 0.000
Z51.1 Chemotherapy session for neoplasm
0.700 0.300 0.000
H50 Other strabismus
0.698 0.302 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.698 0.302 0.000
H34.8 Other retinal vascular occlusions
0.698 0.302 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.697 0.303 0.000
Z94 Transplanted organ and tissue status
0.695 0.305 0.000
M15 Polyarthrosis
0.695 0.305 0.000
G54 Nerve root and plexus disorders
0.695 0.305 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.695 0.305 0.000
G52 Disorders of other cranial nerves
0.695 0.305 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.694 0.305 0.000
H31 Other disorders of choroid
0.694 0.305 0.000
H30 Chorioretinal inflammation
0.694 0.305 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.694 0.306 0.000
H90-H95 Other disorders of ear
0.694 0.306 0.000
Z47 Other orthopaedic follow-up care
0.693 0.306 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.693 0.307 0.000
M10 Gout
0.692 0.308 0.000
I63 Cerebral infarction
0.692 0.308 0.000
Z45.2 Adjustment and management of vascular access device
0.691 0.309 0.000
O42.9 Premature rupture of membranes, unspecified
0.691 0.309 0.000
L20-L30 Dermatitis and eczema
0.691 0.309 0.000
M81 Osteoporosis without pathological fracture
0.690 0.309 0.000
M24 Other specific joint derangements
0.690 0.310 0.000
M35.3 Polymyalgia rheumatica
0.690 0.310 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.689 0.311 0.000
M49 Spondylopathies in diseases classified elsewhere
0.688 0.312 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.687 0.313 0.000
I20-I25 Ischaemic heart diseases
0.687 0.313 0.000
M77 Other enthesopathies
0.685 0.314 0.000
Z40 Prophylactic surgery
0.684 0.316 0.000
S09 Other and unspecified injuries of head
0.684 0.316 0.000
Z10 Routine general health check-up of defined subpopulation
0.683 0.317 0.000
S42 Fracture of shoulder and upper arm
0.683 0.317 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.683 0.317 0.000
M48.09 Spinal stenosis (Site unspecified)
0.682 0.318 0.000
N93 Other abnormal uterine and vaginal bleeding
0.682 0.318 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.681 0.319 0.000
H27 Other disorders of lens
0.680 0.319 0.000
O84 Multiple delivery
0.680 0.320 0.000
O83 Other assisted single delivery
0.680 0.320 0.000
O81 Single delivery by forceps and vacuum extractor
0.680 0.320 0.000
M46 Other inflammatory spondylopathies
0.680 0.320 0.000
G30-G32 Other degenerative diseases of the nervous system
0.679 0.321 0.000
G51 Facial nerve disorders
0.678 0.321 0.000
I00-I02 Acute rheumatic fever
0.678 0.322 0.000
O36.5 Maternal care for poor foetal growth
0.678 0.322 0.000
M79.67 Pain in limb (Ankle and foot)
0.676 0.324 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.676 0.324 0.000
N89 Other noninflammatory disorders of vagina
0.676 0.324 0.000
K80 Cholelithiasis
0.676 0.324 0.000
K70-K77 Diseases of liver
0.675 0.325 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.674 0.325 0.000
M25.77 Osteophyte (Ankle and foot)
0.674 0.326 0.000
I69 Sequelae of cerebrovascular disease
0.673 0.327 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.673 0.327 0.000
M19.8 Other specified arthrosis
0.673 0.327 0.000
M19.2 Other secondary arthrosis
0.673 0.327 0.000
M19.1 Posttraumatic arthrosis of other joints
0.673 0.327 0.000
M76 Enthesopathies of lower limb, excluding foot
0.672 0.328 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.672 0.328 0.000
M71 Other bursopathies
0.672 0.328 0.000
O45 Premature separation of placenta [abruptio placentae]
0.671 0.329 0.000
O44 Placenta praevia
0.671 0.329 0.000
O43 Placental disorders
0.671 0.329 0.000
O41 Other disorders of amniotic fluid and membranes
0.671 0.329 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.671 0.329 0.000
O33 Maternal care for known or suspected disproportion
0.671 0.329 0.000
O31 Complications specific to multiple gestation
0.671 0.329 0.000
O30 Multiple gestation
0.671 0.329 0.000
O40 Polyhydramnios
0.671 0.329 0.000
N70 Salpingitis and oophoritis
0.671 0.329 0.000
M13.8 Other specified arthritis
0.670 0.330 0.000
M13.1 Monoarthritis, not elsewhere classified
0.670 0.330 0.000
M13.0 Polyarthritis, unspecified
0.670 0.330 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.670 0.330 0.000
F99-F99 Unspecified mental disorder
0.669 0.330 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.669 0.330 0.000
F80-F89 Disorders of psychological development
0.669 0.330 0.000
F70-F79 Mental retardation
0.669 0.330 0.000
F60-F69 Disorders of adult personality and behaviour
0.669 0.330 0.000
S81 Open wound of lower leg
0.669 0.331 0.000
O71 Other obstetric trauma
0.668 0.332 0.000
I85 Oesophageal varices
0.668 0.332 0.000
O82 Single delivery by Caesarean section
0.667 0.333 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.667 0.333 0.000
M16.0 Primary coxarthrosis, bilateral
0.666 0.334 0.000
M06.8 Other specified rheumatoid arthritis
0.665 0.334 0.000
M06.4 Inflammatory polyarthropathy
0.665 0.334 0.000
M06.3 Rheumatoid nodule
0.665 0.334 0.000
M06.2 Rheumatoid bursitis
0.665 0.334 0.000
M06.1 Adult-onset Still's disease
0.665 0.334 0.000
M06.0 Seronegative rheumatoid arthritis
0.665 0.334 0.000
M16.1 Other primary coxarthrosis
0.665 0.335 0.000
L40-L45 Papulosquamous disorders
0.665 0.335 0.000
H80-H83 Diseases of inner ear
0.665 0.335 0.000
M47 Spondylosis
0.665 0.335 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.664 0.336 0.000
G58.8 Other specified mononeuropathies
0.664 0.336 0.000
I62 Other nontraumatic intracranial haemorrhage
0.664 0.336 0.000
N36.3 Prolapsed urethral mucosa
0.662 0.338 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.662 0.338 0.000
Z96 Presence of other functional implants
0.662 0.338 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.661 0.339 0.000
Z53.9 Procedure not carried out, unspecified reason
0.661 0.339 0.000
H51 Other disorders of binocular movement
0.661 0.339 0.000
H49 Paralytic strabismus
0.661 0.339 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.661 0.339 0.000
L50-L54 Urticaria and erythema
0.660 0.339 0.000
M48.9 Spondylopathy, unspecified
0.660 0.340 0.000
M48.8 Other specified spondylopathies
0.660 0.340 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.660 0.340 0.000
M48.4 Fatigue fracture of vertebra
0.660 0.340 0.000
M48.3 Traumatic spondylopathy
0.660 0.340 0.000
M48.2 Kissing spine
0.660 0.340 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.660 0.340 0.000
H25.8 Other senile cataract
0.659 0.341 0.000
O80.8 Other single spontaneous delivery
0.658 0.342 0.000
O80.1 Spontaneous breech delivery
0.658 0.342 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.658 0.342 0.000
N30 Cystitis
0.658 0.342 0.000
L10-L14 Bullous disorders
0.658 0.342 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.658 0.342 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.657 0.343 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.656 0.344 0.000
G56.8 Other mononeuropathies of upper limb
0.656 0.344 0.000
G56.4 Causalgia
0.656 0.344 0.000
G56.3 Lesion of radial nerve
0.656 0.344 0.000
G56.1 Other lesions of median nerve
0.656 0.344 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.656 0.344 0.000
M20.3 Other deformity of hallux (acquired)
0.656 0.344 0.000
T51 Toxic effect of alcohol
0.656 0.344 0.000
Z35 Supervision of high-risk pregnancy
0.656 0.344 0.000
H21.8 Other specified disorders of iris and ciliary body
0.655 0.344 0.000
F20 Schizophrenia
0.655 0.345 0.000
M18 Arthrosis of first carpometacarpal joint
0.655 0.345 0.000
H35.4 Peripheral retinal degeneration
0.655 0.345 0.000
M25.76 Osteophyte (Lower leg)
0.655 0.345 0.000
O36.9 Maternal care for foetal problem, unspecified
0.654 0.346 0.000
Z89 Acquired absence of limb
0.654 0.346 0.000
Z84 Family history of other conditions
0.654 0.346 0.000
Z81 Family history of mental and behavioural disorders
0.654 0.346 0.000
Z43.9 Attention to unspecified artificial opening
0.653 0.346 0.000
Z43.8 Attention to other artificial openings
0.653 0.346 0.000
Z43.7 Attention to artificial vagina
0.653 0.346 0.000
Z43.5 Attention to cyctostomy
0.653 0.346 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.653 0.346 0.000
Z43.1 Attention to gastrostomy
0.653 0.346 0.000
Z43.0 Attention to tracheostomy
0.653 0.346 0.000
N98 Complications associated with artificial fertilisation
0.653 0.346 0.000
N91 Absent, scanty and rare menstruation
0.653 0.346 0.000
N82 Fistulae involving female genital tract
0.653 0.346 0.000
N96 Habitual aborter
0.653 0.346 0.000
F32.0 Mild depressive episode
0.652 0.348 0.000
M84 Disorders of continuity of bone
0.651 0.348 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.651 0.349 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.651 0.349 0.000
F33 Recurrent depressive disorder
0.651 0.349 0.000
H33.2 Serous retinal detachment
0.651 0.349 0.000
H02 Other disorders of eyelid
0.650 0.350 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.650 0.350 0.000
O62 Abnormalities of forces of labour
0.650 0.350 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.649 0.351 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.649 0.351 0.000
S70-S79 Injuries to the hip and thigh
0.649 0.351 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.649 0.351 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.649 0.351 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.649 0.351 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.649 0.351 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.649 0.351 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.648 0.351 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.648 0.352 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.648 0.352 0.000
H17 Corneal scars and opacities
0.648 0.352 0.000
H16 Keratitis
0.648 0.352 0.000
H15 Disorders of sclera
0.648 0.352 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.648 0.352 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.648 0.352 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.648 0.352 0.000
M79.9 Soft tissue disorder, unspecified
0.648 0.352 0.000
M79.5 Residual foreign body in soft tissue
0.648 0.352 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.648 0.352 0.000
M79.3 Panniculitis, unspecified
0.648 0.352 0.000
M79.2 Neuralgia and neuritis, unspecified
0.648 0.352 0.000
M79.1 Myalgia
0.648 0.352 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.647 0.353 0.000
Z97.4 Presence of external hearing-aid
0.646 0.354 0.000
N80.8 Other endometriosis
0.646 0.354 0.000
N35 Urethral stricture
0.646 0.354 0.000
Z98.0 Intestinal bypass and anastomosis status
0.646 0.354 0.000
T39.1 4-Aminophenol derivatives
0.645 0.354 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.645 0.355 0.000
Z34 Supervision of normal pregnancy
0.645 0.355 0.000
H43-H45 Disorders of vitreous body and globe
0.644 0.356 0.000
S01 Open wound of head
0.644 0.356 0.000
N80.1 Endometriosis of ovary
0.644 0.356 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.643 0.357 0.000
L60 Nail disorders
0.643 0.357 0.000
M13.98 Arthritis, unspecified (Other)
0.643 0.357 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.643 0.357 0.000
Z87.8 Personal history of other specified conditions
0.643 0.357 0.000
Z86.7 Personal history of diseases of the circulatory system
0.643 0.357 0.000
K65-K67 Diseases of peritoneum
0.642 0.358 0.000
O63 Long labour
0.641 0.359 0.000
F38 Other mood [affective] disorders
0.641 0.359 0.000
F34 Persistent mood [affective] disorders
0.641 0.359 0.000
F30 Manic episode
0.641 0.359 0.000
F39 Unspecified mood [affective] disorder
0.641 0.359 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.641 0.359 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.639 0.360 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.639 0.360 0.000
M48.04 Spinal stenosis (Thoracic region)
0.639 0.360 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.639 0.360 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.639 0.360 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.639 0.360 0.000
H40.0 Glaucoma suspect
0.639 0.360 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.639 0.361 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.639 0.361 0.000
H35.8 Other specified retinal disorders
0.638 0.362 0.000
T92 Sequelae of injuries of upper limb
0.638 0.362 0.000
Z36 Antenatal screening
0.637 0.362 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.637 0.363 0.000
N76 Other inflammation of vagina and vulva
0.637 0.363 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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