TreeWAS – Variant ID: rs116996941

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I20-I25 Ischaemic heart diseases	1.000	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
J30-J39 Other diseases of upper respiratory tract	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
Z40-Z54 Persons encountering health services for specific procedures and health care	0.999	0.001
I25 Chronic ischaemic heart disease	0.999	0.001
I30-I52 Other forms of heart disease	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
Z92 Personal history of medical treatment	0.998	0.002
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.998	0.002
Z95 Presence of cardiac and vascular implants and grafts	0.996	0.004
J34 Other disorders of nose and nasal sinuses	0.994	0.006
Chapter I Certain infectious and parasitic diseases	0.991	0.009
J33 Nasal polyp	0.990	0.010
Z50 Care involving use of rehabilitation procedures	0.989	0.011
Z92.2 Personal history of long-term (current) use of other medicaments	0.989	0.011
I20 Angina pectoris	0.988	0.012
Z45 Adjustment and management of implanted device	0.988	0.012
M15-M19 Arthrosis	0.988	0.012
M19 Other arthrosis	0.987	0.013
I10-I15 Hypertensive diseases	0.987	0.013
T81 Complications of procedures, not elsewhere classified	0.986	0.014
M19.9 Arthrosis, unspecified	0.986	0.014
Z86 Personal history of certain other diseases	0.980	0.020
M20-M25 Other joint disorders	0.980	0.020
I25.1 Atherosclerotic heart disease	0.977	0.023
Chapter XX External causes of morbidity and mortality	0.972	0.028
J33.9 Nasal polyp, unspecified	0.970	0.030
J32 Chronic sinusitis	0.969	0.031
I24 Other acute ischaemic heart diseases	0.968	0.032
Z45.0 Adjustment and management of cardiac pacemaker	0.968	0.032
J34.8 Other specified disorders of nose and nasal sinuses	0.967	0.033
Z96 Presence of other functional implants	0.964	0.036
I10 Essential (primary) hypertension	0.962	0.038
B95-B98 Bacterial, viral and other infectious agents	0.960	0.040
Z86.7 Personal history of diseases of the circulatory system	0.960	0.040
I20.8 Other forms of angina pectoris	0.958	0.042
I25.9 Chronic ischaemic heart disease, unspecified	0.957	0.043
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.954	0.046
M80-M85 Disorders of bone density and structure	0.947	0.053
T81.3 Disruption of operation wound, not elsewhere classified	0.941	0.059
M45-M49 Spondylopathies	0.940	0.060
Z80 Family history of malignant neoplasm	0.939	0.061
J32.9 Chronic sinusitis, unspecified	0.938	0.062
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.937	0.063
Chapter IV Endocrine, nutritional and metabolic diseases	0.937	0.063
I24.9 Acute ischaemic heart disease, unspecified	0.934	0.066
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.934	0.066
I47 Paroxysmal tachycardia	0.934	0.066
Z51 Other medical care	0.931	0.069
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.930	0.070
Z50.1 Other physical therapy	0.930	0.070
I25.8 Other forms of chronic ischaemic heart disease	0.929	0.071
M19.90 Arthrosis, unspecified (Multiple sites)	0.923	0.077
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.923	0.077
J34.2 Deviated nasal septum	0.922	0.078
M19.97 Arthrosis, unspecified (Ankle and foot)	0.919	0.081
Z95.3 Presence of xenogenic heart valve	0.919	0.081
I50 Heart failure	0.919	0.081
Z95.8 Presence of other cardiac and vascular implants and grafts	0.918	0.082
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.916	0.084
Z50.8 Care involving use of rehabilitation procedures	0.913	0.087
Z80.3 Family history of malignant neoplasm of breast	0.910	0.090
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.907	0.093
T81.4 Infection following a procedure, not elsewhere classified	0.906	0.094
Z92.1 Personal history of long-term (current) use of anticoagulants	0.902	0.098
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.901	0.099
M21 Other acquired deformities of limbs	0.901	0.099
Z45.2 Adjustment and management of vascular access device	0.897	0.103
I44 Atrioventricular and left bundle-branch block	0.889	0.111
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.889	0.111
M47 Spondylosis	0.885	0.115
I12 Hypertensive renal disease	0.885	0.115
M19.99 Arthrosis, unspecified (Site unspecified)	0.884	0.116
M19.0 Primary arthrosis of other joints	0.879	0.121
Z94 Transplanted organ and tissue status	0.878	0.122
I38 Endocarditis, valve unspecified	0.878	0.122
Z86.6 Personal history of diseases of the nervous system and sense organs	0.878	0.122
Z92.0 Personal history of contraception	0.877	0.123
W00-W19 Falls	0.875	0.125
Z96.8 Presence of other specified functional implants	0.874	0.126
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.873	0.127
J33.0 Polyp of nasal cavity	0.872	0.128
A00-A09 Intestinal infectious diseases	0.870	0.130
I05-I09 Chronic rheumatic heart diseases	0.869	0.131
Z88.2 Personal history of allergy to sulphonamides	0.869	0.131
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.867	0.133
M80 Osteoporosis with pathological fracture	0.866	0.134
Z95.2 Presence of prosthetic heart valve	0.866	0.134
I20.9 Angina pectoris, unspecified	0.862	0.138
M19.91 Arthrosis, unspecified (Shoulder region)	0.862	0.138
I49 Other cardiac arrhythmias	0.857	0.143
Chapter VII Diseases of the eye and adnexa	0.856	0.144
M25 Other joint disorders, not elsewhere classified	0.856	0.144
Z86.4 Personal history of psychoactive substance abuse	0.853	0.147
E20-E35 Disorders of other endocrine glands	0.853	0.147
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.853	0.147
Z95.0 Presence of cardiac pacemaker	0.850	0.149
J30 Vasomotor and allergic rhinitis	0.850	0.150
J95-J99 Other diseases of the respiratory system	0.849	0.151
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.849	0.151
I25.2 Old myocardial infarction	0.848	0.152
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.847	0.153
Z92.4 Personal history of major surgery, not elsewhere classified	0.846	0.154
Z96.0 Presence of urogenital implants	0.843	0.157
I47.2 Ventricular tachycardia	0.840	0.160
Z89 Acquired absence of limb	0.839	0.161
T85 Complications of other internal prosthetic devices, implants and grafts	0.839	0.161
M47.8 Other spondylosis	0.838	0.162
I50.0 Congestive heart failure	0.837	0.163
R26 Abnormalities of gait and mobility	0.836	0.164
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.833	0.167
T79-T79 Certain early complications of trauma	0.832	0.168
I12.0 Hypertensive renal disease with renal failure	0.829	0.171
I45 Other conduction disorders	0.829	0.171
M23 Internal derangement of knee	0.827	0.173
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.827	0.173
I20.0 Unstable angina	0.826	0.174
Z88.1 Personal history of allergy to other antibiotic agents	0.826	0.174
T20-T25 Burns and corrosions of external body surface, specified by site	0.825	0.175
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.824	0.176
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.823	0.177
J34.3 Hypertrophy of nasal turbinates	0.822	0.177
Z51.4 Preparatory care for treatment, not elsewhere classified	0.819	0.181
S80-S89 Injuries to the knee and lower leg	0.816	0.184
S20-S29 Injuries to the thorax	0.815	0.185
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.813	0.187
Z40 Prophylactic surgery	0.813	0.187
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.812	0.188
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.812	0.188
B99-B99 Other infectious diseases	0.810	0.189
R21 Rash and other nonspecific skin eruption	0.809	0.191
A80-A89 Viral infections of the central nervous system	0.809	0.191
M80.9 Unspecified osteoporosis with pathological fracture	0.808	0.192
R07 Pain in throat and chest	0.808	0.192
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.806	0.194
R26.8 Other and unspecified abnormalities of gait and mobility	0.806	0.194
Chapter XII Diseases of the skin and subcutaneous tissue	0.805	0.195
Z87 Personal history of other diseases and conditions	0.804	0.196
T81.9 Unspecified complication of procedure	0.804	0.196
I24.8 Other forms of acute ischaemic heart disease	0.804	0.196
B97 Viral agents as the cause of diseases classified to other chapters	0.804	0.196
I51 Complications and ill-defined descriptions of heart disease	0.802	0.198
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.802	0.198
R47-R49 Symptoms and signs involving speech and voice	0.802	0.198
I47.1 Supraventricular tachycardia	0.801	0.199
I33 Acute and subacute endocarditis	0.800	0.200
I36 Nonrheumatic tricuspid valve disorders	0.800	0.200
R07.3 Other chest pain	0.798	0.202
Z80.9 Family history of malignant neoplasm, unspecified	0.798	0.202
S00-S09 Injuries to the head	0.797	0.203
M81 Osteoporosis without pathological fracture	0.796	0.204
J60-J70 Lung diseases due to external agents	0.796	0.204
Chapter VI Diseases of the nervous system	0.796	0.204
J00-J06 Acute upper respiratory infections	0.794	0.205
I44.7 Left bundle-branch block, unspecified	0.794	0.206
Z53 Persons encountering health services for specifie procedures, not carried out	0.794	0.206
Z95.4 Presence of other heart-valve replacement	0.792	0.208
I42 Cardiomyopathy	0.791	0.209
S70-S79 Injuries to the hip and thigh	0.791	0.209
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.791	0.209
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.789	0.211
Z88.6 Personal history of allergy to analgesic agent	0.789	0.211
J36 Peritonsillar abscess	0.788	0.212
M21.6 Other acquired deformities of ankle and foot	0.788	0.212
Z96.1 Presence of intraocular lens	0.788	0.212
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.787	0.213
T82.1 Mechanical complication of cardiac electronic device	0.783	0.217
M19.98 Arthrosis, unspecified (Other)	0.781	0.219
M19.94 Arthrosis, unspecified (Hand)	0.781	0.219
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.779	0.221
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.777	0.223
Z93 Artificial opening status	0.776	0.224
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.774	0.226
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.773	0.227
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.771	0.229
M35 Other systemic involvement of connective tissue	0.768	0.232
Y83.1 Surgical operation with implant of artificial internal device	0.768	0.232
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.766	0.234
Z45.1 Adjustment and management of infusion pump	0.766	0.234
T84.3 Mechanical complication of other bone devices, implants and grafts	0.766	0.234
B35-B49 Mycoses	0.765	0.235
Y83.4 Other reconstructive surgery	0.765	0.235
M25.5 Pain in joint	0.765	0.235
I70-I79 Diseases of arteries, arterioles and capillaries	0.765	0.235
Z50.5 Speech therapy	0.764	0.236
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.763	0.237
Z90 Acquired absence of organs, not elsewhere classified	0.762	0.238
M23.3 Other meniscus derangements	0.761	0.239
M48 Other spondylopathies	0.760	0.240
T84.2 Mechanical complication of internal fixation device of other bones	0.760	0.240
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.759	0.241
M19.1 Posttraumatic arthrosis of other joints	0.758	0.242
Z92.8 Personal history of other medical treatment	0.758	0.242
Chapter XXII Codes for special purposes	0.758	0.242
J32.8 Other chronic sinusitis	0.758	0.242
Z95.5 Presence of coronary angioplasty implant and graft	0.757	0.243
I80 Phlebitis and thrombophlebitis	0.757	0.243
T81.8 Other complications of procedures, not elsewhere classified	0.757	0.243
J90-J94 Other diseases of pleura	0.756	0.244
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.756	0.244
M21.0 Valgus deformity, not elsewhere classified	0.755	0.245
I46 Cardiac arrest	0.754	0.246
H25-H28 Disorders of lens	0.753	0.247
I50.1 Left ventricular failure	0.753	0.247
Z80.4 Family history of malignant neoplasm of genital organs	0.752	0.248
J33.8 Other polyp of sinus	0.752	0.248
W19 Unspecified fall	0.749	0.251
J31.2 Chronic pharyngitis	0.749	0.251
I07 Rheumatic tricuspid valve diseases	0.747	0.253
J98 Other respiratory disorders	0.746	0.254
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.746	0.254
J31.0 Chronic rhinitis	0.746	0.254
Z94.8 Other transplanted organ and tissue status	0.746	0.254
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.746	0.254
S90-S99 Injuries to the ankle and foot	0.745	0.254
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.745	0.255
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.745	0.255
M19.04 Primary arthrosis of other joints (Hand)	0.743	0.257
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.742	0.258
T82.0 Mechanical complication of heart valve prosthesis	0.741	0.259
J32.4 Chronic pansinusitis	0.741	0.259
I44.6 Other and unspecified fascicular block	0.741	0.259
E70-E90 Metabolic disorders	0.740	0.260
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.739	0.261
Z90.1 Acquired absence of breast(s)	0.738	0.262
M86-M90 Other osteopathies	0.737	0.263
M20 Acquired deformities of fingers and toes	0.737	0.263
I25.5 Ischaemic cardiomyopathy	0.737	0.263
E40-E46 Malnutrition	0.736	0.264
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.736	0.264
M25.51 Pain in joint (Shoulder region)	0.736	0.264
Z92.6 Personal history of chemotherapy for neoplastic disease	0.735	0.265
A30-A49 Other bacterial diseases	0.735	0.265
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.735	0.265
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.733	0.267
Chapter V Mental and behavioural disorders	0.732	0.268
I45.1 Other and unspecified right bundle-branch block	0.729	0.271
Z51.1 Chemotherapy session for neoplasm	0.725	0.275
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.725	0.275
M47.82 Other spondylosis (Cervical region)	0.725	0.275
Z89.5 Acquired absence of leg at or below knee	0.724	0.276
Z46 Fitting and adjustment of other devices	0.724	0.276
T15-T19 Effects of foreign body entering through natural orifice	0.724	0.276
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.723	0.277
J35 Chronic diseases of tonsils and adenoids	0.722	0.278
Z49 Care involving dialysis	0.722	0.278
I22 Subsequent myocardial infarction	0.722	0.278
D50-D53 Nutritional anaemias	0.721	0.279
Z22 Carrier of infectious disease	0.721	0.279
J30.1 Allergic rhinitis due to pollen	0.721	0.279
M91-M94 Chondropathies	0.720	0.280
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.720	0.280
Z53.0 Procedure not carried out because of contraindication	0.720	0.280
Z96.6 Presence of orthopaedic joint implants	0.719	0.281
Z88.5 Personal history of allergy to narcotic agent	0.718	0.282
I23 Certain current complications following acute myocardial infarction	0.717	0.283
Z84 Family history of other conditions	0.717	0.283
Z81 Family history of mental and behavioural disorders	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
J37 Chronic laryngitis and laryngotracheitis	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
Z54 Convalescence	0.717	0.283
Z44 Fitting and adjustment of external prosthetic device	0.717	0.283
I25.6 Silent myocardial ischaemia	0.716	0.283
I25.4 Coronary artery aneurysm	0.716	0.283
I25.3 Aneurysm of heart	0.716	0.283
I25.0 Atherosclerotic cardiovascular disease, so described	0.716	0.283
I52 Other heart disorders in diseases classified elsewhere	0.716	0.283
I48 Atrial fibrillation and flutter	0.716	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.716	0.283
I41 Myocarditis in diseases classified elsewhere	0.716	0.283
I40 Acute myocarditis	0.716	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.716	0.283
I37 Pulmonary valve disorders	0.716	0.283
I32 Pericarditis in diseases classified elsewhere	0.716	0.283
I30 Acute pericarditis	0.716	0.283
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
S10-S19 Injuries to the neck	0.716	0.284
Z92.9 Personal history of medical treatment, unspecified	0.716	0.284
Z92.5 Personal history of rehabilitation measures	0.716	0.284
T87 Complications peculiar to reattachment and amputation	0.715	0.284
T86 Failure and rejection of transplanted organs and tissues	0.715	0.284
T80 Complications following infusion, transfusion and therapeutic injection	0.715	0.284
Z94.0 Kidney transplant status	0.715	0.285
E65-E68 Obesity and other hyperalimentation	0.714	0.286
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.714	0.286
Z88.3 Personal history of allergy to other anti-infective agents	0.714	0.286
Z95.1 Presence of aortocoronary bypass graft	0.714	0.286
Z97 Presence of other devices	0.713	0.287
J34.1 Cyst and mucocele of nose and nasal sinus	0.713	0.287
J34.0 Abscess, furuncle and carbuncle of nose	0.713	0.287
M85 Other disorders of bone density and structure	0.713	0.287
T79 Certain early complications of trauma, not elsewhere classified	0.713	0.287
Z51.3 Blood transfusion without reported diagnosis	0.712	0.288
M19.93 Arthrosis, unspecified (Forearm)	0.711	0.289
Z43 Attention to artificial openings	0.711	0.289
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.711	0.289
M19.09 Primary arthrosis of other joints (Site unspecified)	0.710	0.290
B90-B94 Sequelae of infectious and parasitic diseases	0.710	0.290
B85-B89 Pediculosis, acariasis and other infestations	0.710	0.290
B65-B83 Helminthiases	0.710	0.290
B50-B64 Protozoal diseases	0.710	0.290
B20-B24 Human immunodeficiency virus [HIV] disease	0.710	0.290
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.710	0.290
A75-A79 Rickettsioses	0.710	0.290
A70-A74 Other diseases caused by chlamydiae	0.710	0.290
A65-A69 Other spirochaetal diseases	0.710	0.290
A20-A28 Certain zoonotic bacterial diseases	0.710	0.290
A15-A19 Tuberculosis	0.710	0.290
H55-H59 Other disorders of eye and adnexa	0.710	0.290
J33.1 Polypoid sinus degeneration	0.710	0.290
X60-X84 Intentional self-harm	0.709	0.290
S06 Intracranial injury	0.709	0.291
Z50.6 Orthoptic training	0.709	0.291
Z50.4 Psychotherapy, not elsewhere classified	0.709	0.291
Z50.3 Drug rehabilitation	0.709	0.291
Z50.2 Alcohol rehabilitation	0.709	0.291
Z45.9 Adjustment and management of unspecified implanted device	0.708	0.292
Z45.3 Adjustment and management of implanted hearing device	0.708	0.292
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.708	0.292
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.708	0.292
M15 Polyarthrosis	0.708	0.292
M19.8 Other specified arthrosis	0.708	0.292
M19.2 Other secondary arthrosis	0.708	0.292
I15 Secondary hypertension	0.708	0.292
I13 Hypertensive heart and renal disease	0.708	0.292
I11 Hypertensive heart disease	0.708	0.292
R47 Speech disturbances, not elsewhere classified	0.707	0.292
T81.7 Vascular complications following a procedure, not elsewhere classified	0.707	0.293
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.707	0.293
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.707	0.293
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.707	0.293
I95-I99 Other and unspecified disorders of the circulatory system	0.707	0.293
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.707	0.293
M22 Disorders of patella	0.707	0.293
M19.92 Arthrosis, unspecified (Upper arm)	0.707	0.293
Q20-Q28 Congenital malformations of the circulatory system	0.706	0.294
A09.9 Gastroenteritis and colitis of unspecified origin	0.706	0.294
I49.5 Sick sinus syndrome	0.706	0.294
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.706	0.294
I49.9 Cardiac arrhythmia, unspecified	0.706	0.294
E16 Other disorders of pancreatic internal secretion	0.705	0.295
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.705	0.295
I49.3 Ventricular premature depolarisation	0.705	0.295
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.703	0.297
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.702	0.298
M34 Systemic sclerosis	0.702	0.298
M33 Dermatopolymyositis	0.702	0.298
M32 Systemic lupus erythematosus	0.702	0.298
M30 Polyarteritis nodosa and related conditions	0.702	0.298
G80-G83 Cerebral palsy and other paralytic syndromes	0.702	0.298
L00-L08 Infections of the skin and subcutaneous tissue	0.702	0.298
Z51.5 Palliative care	0.702	0.298
Z51.0 Radiotherapy session	0.702	0.298
T23 Burn and corrosion of wrist and hand	0.701	0.299
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.700	0.300
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.700	0.300
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.699	0.301
A50-A64 Infections with a predominantly sexual mode of transmission	0.699	0.301
I51.7 Cardiomegaly	0.699	0.301
Y95 Nosocomial condition	0.697	0.302
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.697	0.303
Y35-Y36 Legal intervention and operations of war	0.697	0.303
Y10-Y34 Event of undetermined intent	0.697	0.303
Y00-Y09 Assault	0.697	0.303
X85-X99 Assault	0.697	0.303
X58-X59 Accidental exposure to other and unspecified factors	0.697	0.303
X50-X57 Overexertion, travel and privation	0.697	0.303
X40-X49 Accidental poisoning by and exposure to noxious substances	0.697	0.303
X30-X39 Exposure to forces of nature	0.697	0.303
X20-X29 Contact with venomous animals and plants	0.697	0.303
X10-X19 Contact with heat and hot substances	0.697	0.303
X00-X09 Exposure to smoke, fire and flames	0.697	0.303
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.697	0.303
W75-W84 Other accidental threats to breathing	0.697	0.303
W65-W74 Accidental drowning and submersion	0.697	0.303
W50-W64 Exposure to animate mechanical forces	0.697	0.303
V98-V99 Other and unspecified transport accidents	0.697	0.303
V95-V97 Air and space transport accidents	0.697	0.303
V90-V94 Water transport accidents	0.697	0.303
V80-V89 Other land transport accidents	0.697	0.303
V70-V79 Bus occupant injured in transport accident	0.697	0.303
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.697	0.303
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.697	0.303
V40-V49 Car occupant injured in transport accident	0.697	0.303
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.697	0.303
V01-V09 Pedestrian injured in transport accident	0.697	0.303
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.697	0.303
M84 Disorders of continuity of bone	0.696	0.304
Z80.5 Family history of malignant neoplasm of urinary tract	0.695	0.305
J32.3 Chronic sphenoidal sinusitis	0.695	0.305
J32.2 Chronic ethmoidal sinusitis	0.695	0.305
J32.1 Chronic frontal sinusitis	0.695	0.305
I24.1 Dressler's syndrome	0.694	0.306
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.694	0.306
T84.1 Mechanical complication of internal fixation device of bones of limb	0.692	0.307
Z86.1 Personal history of infectious and parasitic diseases	0.692	0.308
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.692	0.308
M47.80 Other spondylosis (Multiple sites in spine)	0.692	0.308
Z99.3 Dependence on wheelchair	0.692	0.308
I73 Other peripheral vascular diseases	0.692	0.308
Z96.9 Presence of functional implant, unspecified	0.691	0.308
Z96.5 Presence of tooth-root and mandibular implants	0.691	0.308
Z96.4 Presence of endocrine implants	0.691	0.308
Z96.3 Presence of artificial larynx	0.691	0.308
Z96.2 Presence of otological and audiological implants	0.691	0.308
W20-W49 Exposure to inanimate mechanical forces	0.691	0.309
V20-V29 Motorcycle rider injured in transport accident	0.691	0.309
S22 Fracture of rib(s), sternum and thoracic spine	0.691	0.309
M47.87 Other spondylosis (Lumbosacral region)	0.691	0.309
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.690	0.310
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.690	0.310
E34 Other endocrine disorders	0.689	0.311
Z51.2 Other chemotherapy	0.689	0.311
J39 Other diseases of upper respiratory tract	0.688	0.311
R05 Cough	0.688	0.312
M81.9 Osteoporosis, unspecified	0.688	0.312
M65-M68 Disorders of synovium and tendon	0.687	0.313
Chapter VIII Diseases of the ear and mastoid process	0.687	0.313
I20.1 Angina pectoris with documented spasm	0.687	0.313
I82 Other venous embolism and thrombosis	0.687	0.313
M05-M14 Inflammatory polyarthropathies	0.687	0.313
Z70-Z76 Persons encountering health services in other circumstances	0.686	0.314
W08 Fall involving other furniture	0.685	0.315
M24 Other specific joint derangements	0.685	0.315
M47.9 Spondylosis, unspecified	0.684	0.316
Z52 Donors of organs and tissues	0.683	0.317
M31 Other necrotising vasculopathies	0.683	0.317
Z35 Supervision of high-risk pregnancy	0.682	0.318
E23 Hypofunction and other disorders of pituitary gland	0.682	0.318
B99 Other and unspecified infectious diseases	0.681	0.319
M83 Adult osteomalacia	0.679	0.321
M82 Osteoporosis in diseases classified elsewhere	0.679	0.321
S81 Open wound of lower leg	0.679	0.321
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.679	0.321
R23 Other skin changes	0.679	0.321
I08 Multiple valve diseases	0.678	0.322
G35-G37 Demyelinating diseases of the central nervous system	0.678	0.322
B15-B19 Viral hepatitis	0.678	0.322
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.678	0.322
M21.3 Wrist or foot drop (acquired)	0.676	0.324
Z93.2 Ileostomy status	0.676	0.324
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.674	0.326
M25.8 Other specified joint disorders	0.674	0.326
M49 Spondylopathies in diseases classified elsewhere	0.674	0.326
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.674	0.326
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.673	0.327
Z80.6 Family history of leukaemia	0.673	0.327
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.673	0.327
Z51.8 Other specified medical care	0.672	0.328
E50-E64 Other nutritional deficiencies	0.672	0.328
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.672	0.328
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.672	0.328
T82.4 Mechanical complication of vascular dialysis catheter	0.672	0.328
T82.3 Mechanical complication of other vascular grafts	0.672	0.328
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.671	0.329
I60-I69 Cerebrovascular diseases	0.671	0.329
M45 Ankylosing spondylitis	0.671	0.329
W19.4 Street and highway	0.671	0.329
Z80.8 Family history of malignant neoplasm of other organs or systems	0.669	0.330
J32.0 Chronic maxillary sinusitis	0.669	0.330
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.669	0.331
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.669	0.331
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.669	0.331
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.669	0.331
Z82.2 Family history of deafness and hearing loss	0.669	0.331
Z82.1 Family history of blindness and visual loss	0.669	0.331
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.669	0.331
I47.9 Paroxysmal tachycardia, unspecified	0.669	0.331
I47.0 Reentry ventricular arrhythmia	0.669	0.331
E88 Other metabolic disorders	0.668	0.332
Z51.9 Medical care, unspecified	0.667	0.333
Z51.6 Desensitisation to allergens	0.667	0.333
Z96.7 Presence of other bone and tendon implants	0.667	0.333
Z50.0 Cardiac rehabilitation	0.667	0.333
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.667	0.333
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.667	0.333
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.667	0.333
A86 Unspecified viral encephalitis	0.664	0.336
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.664	0.336
Y83.0 Surgical operation with transplant of whole organ	0.664	0.336
W07 Fall involving chair	0.662	0.337
D50 Iron deficiency anaemia	0.662	0.338
R95-R99 Ill-defined and unknown causes of mortality	0.662	0.338
M23.8 Other internal derangements of knee	0.662	0.338
H43-H45 Disorders of vitreous body and globe	0.661	0.339
Y84.0 Cardiac catheterisation	0.661	0.339
R26.3 Immobility	0.659	0.340
W19.2 School, other institution and public administrative area	0.659	0.340
B25-B34 Other viral diseases	0.659	0.341

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations