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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117091124
log Bayes Factor = 7.58899
Chromosome 6   position 94,239,513  (GRCh37) Explore rs117091124 on Ensembl!
Variant rs117091124 is part of Cluster X0261

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
1.000 0.000 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
I10-I15 Hypertensive diseases
0.997 0.003 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.997 0.003 0.000
I20-I25 Ischaemic heart diseases
0.996 0.004 0.000
Z88.6 Personal history of allergy to analgesic agent
0.993 0.007 0.000
Chapter V Mental and behavioural disorders
0.992 0.008 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.989 0.011 0.000
F30-F39 Mood [affective] disorders
0.988 0.012 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.984 0.016 0.000
I20 Angina pectoris
0.965 0.035 0.000
F33 Recurrent depressive disorder
0.964 0.036 0.000
I10 Essential (primary) hypertension
0.960 0.040 0.000
I20.0 Unstable angina
0.958 0.042 0.000
Chapter VIII Diseases of the ear and mastoid process
0.957 0.043 0.000
I21 Acute myocardial infarction
0.952 0.048 0.000
M86-M90 Other osteopathies
0.952 0.048 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.951 0.049 0.000
M05-M14 Inflammatory polyarthropathies
0.949 0.051 0.000
Chapter I Certain infectious and parasitic diseases
0.948 0.052 0.000
F33.9 Recurrent depressive disorder, unspecified
0.948 0.052 0.000
I73 Other peripheral vascular diseases
0.942 0.058 0.000
I11 Hypertensive heart disease
0.937 0.063 0.000
F31 Bipolar affective disorder
0.922 0.078 0.000
M13 Other arthritis
0.920 0.080 0.000
Chapter XXII Codes for special purposes
0.919 0.081 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.918 0.082 0.000
G56 Mononeuropathies of upper limb
0.918 0.082 0.000
B95-B98 Bacterial, viral and other infectious agents
0.909 0.091 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.907 0.093 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.905 0.095 0.000
G30-G32 Other degenerative diseases of the nervous system
0.902 0.098 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.899 0.101 0.000
H60-H62 Diseases of external ear
0.899 0.101 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.894 0.106 0.000
M91-M94 Chondropathies
0.894 0.106 0.000
M87 Osteonecrosis
0.893 0.107 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.893 0.107 0.000
M13.9 Arthritis, unspecified
0.891 0.109 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.884 0.116 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.882 0.118 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.880 0.120 0.000
I73.9 Peripheral vascular disease, unspecified
0.878 0.122 0.000
G90-G99 Other disorders of the nervous system
0.877 0.123 0.000
I15 Secondary hypertension
0.874 0.126 0.000
I22 Subsequent myocardial infarction
0.869 0.131 0.000
H60 Otitis externa
0.866 0.134 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.864 0.136 0.000
G56.0 Carpal tunnel syndrome
0.863 0.137 0.000
I74 Arterial embolism and thrombosis
0.863 0.137 0.000
M70-M79 Other soft tissue disorders
0.858 0.142 0.000
I70 Atherosclerosis
0.850 0.150 0.000
B35-B49 Mycoses
0.845 0.155 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.843 0.157 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.840 0.160 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.838 0.162 0.000
H90-H95 Other disorders of ear
0.838 0.162 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.835 0.165 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.834 0.166 0.000
H60.9 Otitis externa, unspecified
0.830 0.170 0.000
I12 Hypertensive renal disease
0.830 0.170 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.827 0.173 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.826 0.174 0.000
G35 Multiple sclerosis
0.824 0.176 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.819 0.181 0.000
A15-A19 Tuberculosis
0.816 0.184 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.812 0.187 0.000
F34 Persistent mood [affective] disorders
0.812 0.188 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.812 0.188 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.810 0.190 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.807 0.193 0.000
Chapter VII Diseases of the eye and adnexa
0.803 0.197 0.000
H65-H75 Diseases of middle ear and mastoid
0.802 0.198 0.000
M89 Other disorders of bone
0.800 0.200 0.000
Z88.5 Personal history of allergy to narcotic agent
0.797 0.203 0.000
M94 Other disorders of cartilage
0.794 0.206 0.000
I77 Other disorders of arteries and arterioles
0.794 0.206 0.000
M86 Osteomyelitis
0.792 0.208 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.791 0.209 0.000
F43 Reaction to severe stress, and adjustment disorders
0.791 0.209 0.000
M87.9 Osteonecrosis, unspecified
0.789 0.211 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.789 0.211 0.000
Z88.2 Personal history of allergy to sulphonamides
0.789 0.211 0.000
M87.2 Osteonecrosis due to previous trauma
0.788 0.212 0.000
M60-M63 Disorders of muscles
0.787 0.212 0.000
G20-G26 Extrapyramidal and movement disorders
0.787 0.213 0.000
I25 Chronic ischaemic heart disease
0.787 0.213 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.784 0.216 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.781 0.219 0.000
G96 Other disorders of central nervous system
0.776 0.224 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.769 0.231 0.000
G70-G73 Diseases of myoneural junction and muscle
0.765 0.235 0.000
M11 Other crystal arthropathies
0.762 0.238 0.000
I73.8 Other specified peripheral vascular diseases
0.760 0.239 0.000
B44 Aspergillosis
0.758 0.242 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.757 0.243 0.000
I73.0 Raynaud's syndrome
0.756 0.244 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.756 0.244 0.000
M79.7 Fibromyalgia
0.753 0.247 0.000
F32 Depressive episode
0.752 0.248 0.000
I70.0 Atherosclerosis of aorta
0.752 0.248 0.000
I30-I52 Other forms of heart disease
0.750 0.250 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.749 0.250 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.747 0.253 0.000
F45 Somatoform disorders
0.747 0.253 0.000
I25.1 Atherosclerotic heart disease
0.746 0.254 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.743 0.257 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.742 0.258 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.741 0.259 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.741 0.259 0.000
M13.0 Polyarthritis, unspecified
0.738 0.262 0.000
I15.1 Hypertension secondary to other renal disorders
0.736 0.264 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.736 0.264 0.000
M79.8 Other specified soft tissue disorders
0.736 0.264 0.000
G56.8 Other mononeuropathies of upper limb
0.734 0.266 0.000
F30 Manic episode
0.729 0.270 0.000
I21.4 Acute subendocardial myocardial infarction
0.729 0.271 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.729 0.271 0.000
M79.0 Rheumatism, unspecified
0.728 0.272 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.727 0.273 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.725 0.275 0.000
G31.0 Circumscribed brain atrophy
0.725 0.275 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.725 0.275 0.000
I51 Complications and ill-defined descriptions of heart disease
0.724 0.276 0.000
M14 Arthropathies in other diseases classified elsewhere
0.722 0.278 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.721 0.279 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.720 0.280 0.000
G95 Other diseases of spinal cord
0.719 0.281 0.000
G56.1 Other lesions of median nerve
0.718 0.282 0.000
I77.1 Stricture of artery
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.715 0.285 0.000
I15.9 Seconday hypertension, unspecified
0.715 0.285 0.000
I13 Hypertensive heart and renal disease
0.715 0.285 0.000
I23 Certain current complications following acute myocardial infarction
0.714 0.286 0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)
0.713 0.287 0.000
G54 Nerve root and plexus disorders
0.712 0.288 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.711 0.289 0.000
F70-F79 Mental retardation
0.711 0.289 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.711 0.289 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
M94.8 Other specified disorders of cartilage
0.709 0.291 0.000
F38 Other mood [affective] disorders
0.709 0.291 0.000
F39 Unspecified mood [affective] disorder
0.709 0.291 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.709 0.291 0.000
I74.8 Embolism and thrombosis of other arteries
0.708 0.292 0.000
H55-H59 Other disorders of eye and adnexa
0.707 0.293 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.707 0.293 0.000
F43.0 Acute stress reaction
0.707 0.293 0.000
M45-M49 Spondylopathies
0.706 0.294 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.706 0.294 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.706 0.294 0.000
H50 Other strabismus
0.705 0.295 0.000
H91 Other hearing loss
0.704 0.296 0.000
M05 Seropositive rheumatoid arthritis
0.703 0.297 0.000
F31.9 Bipolar affective disorder, unspecified
0.702 0.298 0.000
U89 Agent resistant to other and unspecified antibiotics
0.698 0.302 0.000
H92 Otalgia and effusion of ear
0.698 0.302 0.000
G31.8 Other specified degenerative diseases of nervous system
0.697 0.303 0.000
I72 Other aneurysm
0.696 0.304 0.000
M79.79 Fibromyalgia (Site unspecified)
0.695 0.305 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.695 0.305 0.000
I20.1 Angina pectoris with documented spasm
0.694 0.306 0.000
M07 Psoriatic and enteropathic arthropathies
0.694 0.306 0.000
Q50-Q56 Congenital malformations of genital organs
0.693 0.307 0.000
F41 Other anxiety disorders
0.691 0.309 0.000
F33.8 Other recurrent depressive disorders
0.691 0.309 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.691 0.309 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.691 0.309 0.000
F42 Obsessive-compulsive disorder
0.690 0.310 0.000
I12.0 Hypertensive renal disease with renal failure
0.689 0.311 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.689 0.311 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.689 0.311 0.000
M92 Other juvenile osteochondrosis
0.688 0.311 0.000
M80-M85 Disorders of bone density and structure
0.686 0.314 0.000
F34.1 Dysthymia
0.686 0.314 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.684 0.316 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.683 0.317 0.000
H60.8 Other otitis externa
0.682 0.318 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.682 0.318 0.000
G52 Disorders of other cranial nerves
0.682 0.318 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.681 0.319 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.681 0.319 0.000
M12 Other specific arthropathies
0.681 0.319 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.681 0.319 0.000
M08 Juvenile arthritis
0.681 0.319 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.681 0.319 0.000
U88 Agent resistant to multiple antibiotics
0.680 0.320 0.000
M93 Other osteochondropathies
0.680 0.320 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.680 0.320 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.679 0.321 0.000
B99-B99 Other infectious diseases
0.679 0.321 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.679 0.321 0.000
B50-B64 Protozoal diseases
0.679 0.321 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.679 0.321 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.679 0.321 0.000
A75-A79 Rickettsioses
0.679 0.321 0.000
A70-A74 Other diseases caused by chlamydiae
0.679 0.321 0.000
A65-A69 Other spirochaetal diseases
0.679 0.321 0.000
A20-A28 Certain zoonotic bacterial diseases
0.679 0.321 0.000
Chapter XX External causes of morbidity and mortality
0.679 0.321 0.000
B91 Sequelae of poliomyelitis
0.678 0.322 0.000
M86.9 Osteomyelitis, unspecified
0.677 0.323 0.000
Q00-Q07 Congenital malformations of the nervous system
0.677 0.323 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.675 0.324 0.000
I50 Heart failure
0.674 0.326 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.672 0.328 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.672 0.328 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.670 0.329 0.000
G12 Spinal muscular atrophy and related syndromes
0.669 0.331 0.000
B35 Dermatophytosis
0.669 0.331 0.000
M90 Osteopathies in diseases classified elsewhere
0.667 0.333 0.000
F99-F99 Unspecified mental disorder
0.666 0.334 0.000
M40-M43 Deforming dorsopathies
0.666 0.334 0.000
B49 Unspecified mycosis
0.665 0.335 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.664 0.335 0.000
A30-A49 Other bacterial diseases
0.663 0.337 0.000
M71 Other bursopathies
0.663 0.337 0.000
I51.7 Cardiomegaly
0.662 0.338 0.000
F01 Vascular dementia
0.661 0.339 0.000
F31.8 Other bipolar affective disorders
0.661 0.339 0.000
F31.7 Bipolar affective disorder, currently in remission
0.661 0.339 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.661 0.339 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.661 0.339 0.000
M89.8 Other specified disorders of bone
0.660 0.340 0.000
M13.8 Other specified arthritis
0.660 0.340 0.000
M13.1 Monoarthritis, not elsewhere classified
0.660 0.340 0.000
M79.2 Neuralgia and neuritis, unspecified
0.660 0.340 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.658 0.342 0.000
A80-A89 Viral infections of the central nervous system
0.658 0.342 0.000
G56.4 Causalgia
0.658 0.342 0.000
G56.3 Lesion of radial nerve
0.658 0.342 0.000
B44.1 Other pulmonary aspergillosis
0.658 0.342 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.657 0.343 0.000
G90 Disorders of autonomic nervous system
0.657 0.343 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.657 0.343 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.656 0.344 0.000
G96.8 Other specified disorders of central nervous system
0.656 0.344 0.000
Q80-Q89 Other congenital malformations
0.655 0.345 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.655 0.345 0.000
F80-F89 Disorders of psychological development
0.654 0.346 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.653 0.347 0.000
H60.1 Cellulitis of external ear
0.653 0.347 0.000
I25.4 Coronary artery aneurysm
0.652 0.348 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.652 0.348 0.000
G20 Parkinson's disease
0.650 0.350 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.650 0.350 0.000
Q76 Congenital malformations of spine and bony thorax
0.650 0.350 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.649 0.351 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.649 0.351 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.649 0.351 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.649 0.351 0.000
M94.86 Other specified disorders of cartilage (Lower leg)
0.648 0.352 0.000
I74.5 Embolism and thrombosis of iliac artery
0.647 0.353 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.647 0.353 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.646 0.354 0.000
F48 Other neurotic disorders
0.645 0.355 0.000
F44 Dissociative [conversion] disorders
0.645 0.355 0.000
B65-B83 Helminthiases
0.645 0.355 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.644 0.355 0.000
M62 Other disorders of muscle
0.643 0.357 0.000
M79.5 Residual foreign body in soft tissue
0.643 0.357 0.000
G58 Other mononeuropathies
0.642 0.358 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.642 0.358 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.641 0.359 0.000
H66 Suppurative and unspecified otitis media
0.641 0.359 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.641 0.359 0.000
M87.8 Other osteonecrosis
0.640 0.360 0.000
M87.3 Other secondary osteonecrosis
0.640 0.360 0.000
M87.1 Osteonecrosis due to drugs
0.640 0.360 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.640 0.360 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.640 0.360 0.000
I42 Cardiomyopathy
0.640 0.360 0.000
Q35-Q37 Cleft lip and cleft palate
0.640 0.360 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.640 0.360 0.000
F02 Dementia in other diseases classified elsewhere
0.639 0.361 0.000
M13.93 Arthritis, unspecified (Forearm)
0.639 0.361 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.639 0.361 0.000
H10-H13 Disorders of conjunctiva
0.638 0.362 0.000
H71 Cholesteatoma of middle ear
0.636 0.364 0.000
H70 Mastoiditis and related conditions
0.636 0.364 0.000
G03 Meningitis due to other and unspecified causes
0.635 0.365 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.634 0.365 0.000
G50 Disorders of trigeminal nerve
0.634 0.365 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.634 0.366 0.000
F60-F69 Disorders of adult personality and behaviour
0.634 0.366 0.000
G36 Other acute disseminated demyelination
0.632 0.368 0.000
I78 Diseases of capillaries
0.632 0.368 0.000
G56.2 Lesion of ulnar nerve
0.631 0.369 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.631 0.369 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.631 0.369 0.000
G00 Bacterial meningitis, not elsewhere classified
0.631 0.369 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.631 0.369 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.631 0.369 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.631 0.369 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.631 0.369 0.000
B15-B19 Viral hepatitis
0.631 0.369 0.000
U80 Agent resistant to penicillin and related antibiotics
0.631 0.369 0.000
F03 Unspecified dementia
0.630 0.370 0.000
I35 Nonrheumatic aortic valve disorders
0.629 0.371 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.629 0.371 0.000
G92 Toxic encephalopathy
0.629 0.371 0.000
M10 Gout
0.629 0.371 0.000
I12.9 Hypertensive renal disease without renal failure
0.629 0.371 0.000
M11.2 Other chondrocalcinosis
0.628 0.372 0.000
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation
0.628 0.372 0.000
I15.8 Other secondary hypertension
0.626 0.373 0.000
I15.2 Hypertension secondary to endocrine disorders
0.626 0.373 0.000
I15.0 Renovascular hypertension
0.626 0.373 0.000
F32.1 Moderate depressive episode
0.626 0.374 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.626 0.374 0.000
B44.9 Aspergillosis, unspecified
0.626 0.374 0.000
H20 Iridocyclitis
0.625 0.375 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.624 0.376 0.000
I26 Pulmonary embolism
0.624 0.376 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.624 0.376 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.624 0.376 0.000
M89.9 Disorder of bone, unspecified
0.623 0.377 0.000
H57 Other disorders of eye and adnexa
0.623 0.377 0.000
H60.5 Acute otitis externa, non-infective
0.621 0.379 0.000
H60.4 Cholesteatoma of external ear
0.621 0.379 0.000
H60.3 Other infective otitis externa
0.621 0.379 0.000
H60.2 Malignant otitis externa
0.621 0.379 0.000
H60.0 Abscess of external ear
0.621 0.379 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.620 0.380 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.620 0.380 0.000
H50.9 Strabismus, unspecified
0.619 0.381 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.618 0.381 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.618 0.381 0.000
M88 Paget's disease of bone [osteitis deformans]
0.618 0.382 0.000
G96.0 Cerebrospinal fluid leak
0.617 0.383 0.000
G30 Alzheimer's disease
0.617 0.383 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.616 0.384 0.000
M76 Enthesopathies of lower limb, excluding foot
0.615 0.384 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.615 0.384 0.000
F32.8 Other depressive episodes
0.615 0.385 0.000
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)
0.615 0.385 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.614 0.386 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.614 0.386 0.000
B25-B34 Other viral diseases
0.613 0.387 0.000
I50.1 Left ventricular failure
0.613 0.387 0.000
H91.9 Hearing loss, unspecified
0.613 0.387 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.612 0.388 0.000
U89.8 Agent resistant to other single specified antibiotic
0.612 0.388 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.612 0.388 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.610 0.389 0.000
I70.9 Generalised and unspecified atherosclerosis
0.610 0.390 0.000
I70.8 Atherosclerosis of other arteries
0.610 0.390 0.000
I70.1 Atherosclerosis of renal artery
0.610 0.390 0.000
M94.9 Disorder of cartilage, unspecified
0.609 0.391 0.000
F45.9 Somatoform disorder, unspecified
0.609 0.391 0.000
H40-H42 Glaucoma
0.607 0.393 0.000
B48 Other mycoses, not elsewhere classified
0.606 0.394 0.000
B47 Mycetoma
0.606 0.394 0.000
B46 Zygomycosis
0.606 0.394 0.000
B45 Cryptococcosis
0.606 0.394 0.000
B43 Chromomycosis and phaeomycotic abscess
0.606 0.394 0.000
B42 Sporotrichosis
0.606 0.394 0.000
B41 Paracoccidioidomycosis
0.606 0.394 0.000
B40 Blastomycosis
0.606 0.394 0.000
B39 Histoplasmosis
0.606 0.394 0.000
B38 Coccidioidomycosis
0.606 0.394 0.000
B36 Other superficial mycoses
0.606 0.394 0.000
Q90 Down's syndrome
0.605 0.395 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.605 0.395 0.000
I77.0 Arteriovenous fistula, acquired
0.604 0.396 0.000
H43-H45 Disorders of vitreous body and globe
0.604 0.396 0.000
G31.2 Degeneration of nervous system due to alcohol
0.602 0.397 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.602 0.397 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.602 0.398 0.000
M46 Other inflammatory spondylopathies
0.601 0.399 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.601 0.399 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.601 0.399 0.000
H69 Other disorders of Eustachian tube
0.599 0.401 0.000
M79.9 Soft tissue disorder, unspecified
0.599 0.401 0.000
M79.3 Panniculitis, unspecified
0.599 0.401 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.598 0.402 0.000
F09 Unspecified organic or symptomatic mental disorder
0.598 0.402 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.598 0.402 0.000
H73 Other disorders of tympanic membrane
0.598 0.402 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.597 0.403 0.000
Chapter XXI Factors influencing health status and contact with health services
0.596 0.404 0.000
H53-H54 Visual disturbances and blindness
0.596 0.404 0.000
M20-M25 Other joint disorders
0.596 0.404 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.595 0.405 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.595 0.405 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.595 0.405 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.594 0.406 0.000
I22.8 Subsequent myocardial infarction of other sites
0.593 0.407 0.000
F43.1 Posttraumatic stress disorder
0.593 0.407 0.000
G57 Mononeuropathies of lower limb
0.593 0.407 0.000
H72 Perforation of tympanic membrane
0.590 0.409 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.590 0.410 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.590 0.410 0.000
I71 Aortic aneurysm and dissection
0.589 0.411 0.000
U84 Resistance to other antimicrobial drugs
0.587 0.413 0.000
U83 Resistance to other antibiotics
0.587 0.413 0.000
U82 Resistance to betalactam antibiotics
0.587 0.413 0.000
U85 Resistance to antineoplastic drugs
0.587 0.413 0.000
I51.8 Other ill-defined heart diseases
0.587 0.413 0.000
M65-M68 Disorders of synovium and tendon
0.585 0.415 0.000
H50.0 Convergent concomitant strabismus
0.585 0.415 0.000
A19 Miliary tuberculosis
0.585 0.415 0.000
A18 Tuberculosis of other organs
0.585 0.415 0.000
A17 Tuberculosis of nervous system
0.585 0.415 0.000
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed
0.585 0.415 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.583 0.417 0.000
F34.9 Persistent mood [affective] disorder, unspecified
0.582 0.418 0.000
F34.8 Other persistent mood [affective] disorders
0.582 0.418 0.000
F34.0 Cyclothymia
0.582 0.418 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.582 0.418 0.000
G25 Other extrapyramidal and movement disorders
0.582 0.418 0.000
G70 Myasthenia gravis and other myoneural disorders
0.582 0.418 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.582 0.418 0.000
F45.8 Other somatoform disorders
0.581 0.419 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.580 0.420 0.000
M84 Disorders of continuity of bone
0.580 0.420 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.579 0.421 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.578 0.422 0.000
G11 Hereditary ataxia
0.578 0.422 0.000
G14 Postpolio syndrome
0.578 0.422 0.000
G10 Huntington's disease
0.578 0.422 0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.578 0.422 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.578 0.422 0.000
I24 Other acute ischaemic heart diseases
0.577 0.423 0.000
G95.2 Cord compression, unspecified
0.576 0.423 0.000
H50.2 Vertical strabismus
0.576 0.424 0.000
I36 Nonrheumatic tricuspid valve disorders
0.576 0.424 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.575 0.425 0.000
H68 Eustachian salpingitis and obstruction
0.575 0.425 0.000
H67 Otitis media in diseases classified elsewhere
0.575 0.425 0.000
H61 Other disorders of external ear
0.575 0.425 0.000
M89.6 Osteopathy after poliomyelitis
0.573 0.426 0.000
M89.5 Osteolysis
0.573 0.426 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.573 0.426 0.000
M89.3 Hypertrophy of bone
0.573 0.426 0.000
M89.2 Other disorders of bone development and growth
0.573 0.426 0.000
M89.1 Epiphyseal arrest
0.573 0.426 0.000
M89.0 Algoneurodystrophy
0.573 0.426 0.000
O85-O92 Complications predominantly related to the puerperium
0.573 0.427 0.000
I20.8 Other forms of angina pectoris
0.573 0.427 0.000
Q65 Congenital deformities of hip
0.573 0.427 0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation
0.573 0.427 0.000
H93 Other disorders of ear, not elsewhere classified
0.571 0.428 0.000
H74 Other disorders of middle ear and mastoid
0.571 0.429 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.571 0.429 0.000
H92.1 Otorrhoea
0.571 0.429 0.000
G12.2 Motor neuron disease
0.571 0.429 0.000
M94.3 Chondrolysis
0.569 0.430 0.000
M94.1 Relapsing polychondritis
0.569 0.430 0.000
M94.0 Chondrocostal junction syndrome [Tietze]
0.569 0.430 0.000
I50.9 Heart failure, unspecified
0.569 0.431 0.000
I77.5 Necrosis of artery
0.569 0.431 0.000
I77.4 Coeliac artery compression syndrome
0.569 0.431 0.000
I77.3 Arterial fibromuscular dysplasia
0.569 0.431 0.000
I77.2 Rupture of artery
0.569 0.431 0.000
M79.88 Other specified soft tissue disorders (Other)
0.569 0.431 0.000
F06.7 Mild cognitive disorder
0.568 0.432 0.000
M86.8 Other osteomyelitis
0.568 0.432 0.000
M86.6 Other chronic osteomyelitis
0.568 0.432 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.568 0.432 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.568 0.432 0.000
M86.3 Chronic multifocal osteomyelitis
0.568 0.432 0.000
M86.2 Subacute osteomyelitis
0.568 0.432 0.000
M86.1 Other acute osteomyelitis
0.568 0.432 0.000
M86.0 Acute haematogenous osteomyelitis
0.568 0.432 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.568 0.432 0.000
B94 Sequelae of other and unspecified infectious and parasitic diseases
0.567 0.433 0.000
B90 Sequelae of tuberculosis
0.567 0.433 0.000
B92 Sequelae of leprosy
0.567 0.433 0.000
F43.9 Reaction to severe stress, unspecified
0.567 0.433 0.000
F43.8 Other reactions to severe stress
0.567 0.433 0.000
I51.4 Myocarditis, unspecified
0.567 0.433 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.566 0.433 0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)
0.566 0.434 0.000
M87.98 Osteonecrosis, unspecified (Other)
0.566 0.434 0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)
0.566 0.434 0.000
M87.96 Osteonecrosis, unspecified (Lower leg)
0.566 0.434 0.000
M87.94 Osteonecrosis, unspecified (Hand)
0.566 0.434 0.000
M87.93 Osteonecrosis, unspecified (Forearm)
0.566 0.434 0.000
M87.92 Osteonecrosis, unspecified (Upper arm)
0.566 0.434 0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)
0.566 0.434 0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)
0.566 0.434 0.000
G71 Primary disorders of muscles
0.565 0.434 0.000
M94.2 Chondromalacia
0.565 0.434 0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)
0.565 0.435 0.000
M87.28 Osteonecrosis due to previous trauma (Other)
0.565 0.435 0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)
0.565 0.435 0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)
0.565 0.435 0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)
0.565 0.435 0.000
M87.24 Osteonecrosis due to previous trauma (Hand)
0.565 0.435 0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)
0.565 0.435 0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)
0.565 0.435 0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)
0.565 0.435 0.000
M77 Other enthesopathies
0.565 0.435 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.565 0.435 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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