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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117131051
log Bayes Factor = 12.836
Chromosome 18   position 25,336,648  (GRCh37) Explore rs117131051 on Ensembl!
Variant rs117131051 is part of Cluster X0284

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.998 0.002 0.000
S00-S09 Injuries to the head
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.995 0.005 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.994 0.006 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.992 0.008 0.000
F17.1 Harmful use
0.989 0.011 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.988 0.012 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.984 0.016 0.000
L90 Atrophic disorders of skin
0.981 0.019 0.000
M23 Internal derangement of knee
0.973 0.027 0.000
L90.5 Scar conditions and fibrosis of skin
0.973 0.027 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.971 0.029 0.000
S50-S59 Injuries to the elbow and forearm
0.971 0.029 0.000
S00 Superficial injury of head
0.966 0.034 0.000
L40-L45 Papulosquamous disorders
0.961 0.039 0.000
M25 Other joint disorders, not elsewhere classified
0.959 0.041 0.000
Chapter IX Diseases of the circulatory system
0.952 0.048 0.000
I30-I52 Other forms of heart disease
0.950 0.050 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.950 0.050 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.949 0.051 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.948 0.052 0.000
Chapter VI Diseases of the nervous system
0.945 0.055 0.000
L40 Psoriasis
0.939 0.061 0.000
M65-M68 Disorders of synovium and tendon
0.935 0.065 0.000
M24 Other specific joint derangements
0.932 0.068 0.000
M25.5 Pain in joint
0.922 0.078 0.000
W00-W19 Falls
0.917 0.083 0.000
S52 Fracture of forearm
0.915 0.085 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.915 0.085 0.000
I50 Heart failure
0.911 0.089 0.000
S60-S69 Injuries to the wrist and hand
0.906 0.094 0.000
M20 Acquired deformities of fingers and toes
0.906 0.094 0.000
M86-M90 Other osteopathies
0.904 0.096 0.000
S09 Other and unspecified injuries of head
0.903 0.097 0.000
Chapter VII Diseases of the eye and adnexa
0.903 0.097 0.000
M23.3 Other meniscus derangements
0.903 0.097 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.899 0.101 0.000
F10.0 Acute intoxication
0.899 0.101 0.000
M25.51 Pain in joint (Shoulder region)
0.897 0.103 0.000
S00.0 Superficial injury of scalp
0.890 0.110 0.000
L40.5 Arthropathic psoriasis
0.881 0.119 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.873 0.127 0.000
I50.1 Left ventricular failure
0.873 0.127 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.871 0.129 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.870 0.130 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.867 0.133 0.000
M70-M79 Other soft tissue disorders
0.867 0.133 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.864 0.136 0.000
S06 Intracranial injury
0.860 0.140 0.000
S90-S99 Injuries to the ankle and foot
0.859 0.141 0.000
L89 Decubitus ulcer
0.856 0.144 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.856 0.144 0.000
I47 Paroxysmal tachycardia
0.854 0.146 0.000
M20.1 Hallux valgus (acquired)
0.854 0.146 0.000
F60-F69 Disorders of adult personality and behaviour
0.852 0.148 0.000
I35 Nonrheumatic aortic valve disorders
0.851 0.149 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.851 0.149 0.000
F10.4 Withdrawal state with delirium
0.851 0.149 0.000
L40.9 Psoriasis, unspecified
0.847 0.153 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.844 0.156 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.843 0.157 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.840 0.160 0.000
G90-G99 Other disorders of the nervous system
0.840 0.160 0.000
S00.5 Superficial injury of lip and oral cavity
0.839 0.161 0.000
T87 Complications peculiar to reattachment and amputation
0.839 0.161 0.000
Y00-Y09 Assault
0.838 0.162 0.000
S00.9 Superficial injury of head, part unspecified
0.837 0.163 0.000
M67 Other disorders of synovium and tendon
0.835 0.165 0.000
S52.5 Fracture of lower end of radius
0.834 0.166 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.834 0.166 0.000
S80-S89 Injuries to the knee and lower leg
0.833 0.167 0.000
T42.4 Benzodiazepines
0.829 0.171 0.000
S09.9 Unspecified injury of head
0.822 0.178 0.000
I35.1 Aortic (valve) insufficiency
0.822 0.178 0.000
L84 Corns and callosities
0.822 0.178 0.000
S02 Fracture of skull and facial bones
0.822 0.178 0.000
S70-S79 Injuries to the hip and thigh
0.821 0.179 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.820 0.179 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.819 0.181 0.000
S51 Open wound of forearm
0.817 0.183 0.000
V40-V49 Car occupant injured in transport accident
0.815 0.185 0.000
S52.0 Fracture of upper end of ulna
0.815 0.185 0.000
I44 Atrioventricular and left bundle-branch block
0.813 0.187 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.813 0.187 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.812 0.188 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.812 0.188 0.000
M65 Synovitis and tenosynovitis
0.812 0.188 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.810 0.190 0.000
F10.3 Withdrawal state
0.807 0.193 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.807 0.193 0.000
L50-L54 Urticaria and erythema
0.806 0.194 0.000
M45-M49 Spondylopathies
0.806 0.194 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.806 0.194 0.000
M89 Other disorders of bone
0.799 0.201 0.000
M25.50 Pain in joint (Multiple sites)
0.799 0.201 0.000
W19 Unspecified fall
0.797 0.203 0.000
F41 Other anxiety disorders
0.796 0.204 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.795 0.205 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.793 0.207 0.000
Y52 Agents primarily affecting the cardiovascular system
0.792 0.208 0.000
T86 Failure and rejection of transplanted organs and tissues
0.792 0.208 0.000
S00.1 Contusion of eyelid and periocular area
0.789 0.211 0.000
I51 Complications and ill-defined descriptions of heart disease
0.789 0.211 0.000
M25.3 Other instability of joint
0.788 0.212 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.787 0.213 0.000
M24.2 Disorder of ligament
0.783 0.217 0.000
M80-M85 Disorders of bone density and structure
0.783 0.217 0.000
L83 Acanthosis nigricans
0.782 0.218 0.000
Y57 Other and unspecified drugs and medicaments
0.776 0.224 0.000
S52.50 Fracture of lower end of radius (closed)
0.776 0.224 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.775 0.225 0.000
M25.58 Pain in joint (Other)
0.774 0.226 0.000
L85 Other epidermal thickening
0.772 0.228 0.000
Chapter XXII Codes for special purposes
0.769 0.231 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.768 0.232 0.000
M25.54 Pain in joint (Hand)
0.768 0.232 0.000
W50-W64 Exposure to animate mechanical forces
0.767 0.233 0.000
M23.0 Cystic meniscus
0.766 0.234 0.000
T79-T79 Certain early complications of trauma
0.765 0.235 0.000
M31 Other necrotising vasculopathies
0.765 0.235 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.765 0.235 0.000
M79.0 Rheumatism, unspecified
0.764 0.236 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.763 0.237 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.763 0.237 0.000
M22 Disorders of patella
0.763 0.237 0.000
G51 Facial nerve disorders
0.762 0.238 0.000
X50-X57 Overexertion, travel and privation
0.759 0.241 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.758 0.242 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.757 0.243 0.000
M60-M63 Disorders of muscles
0.754 0.246 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.753 0.247 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.752 0.248 0.000
S05 Injury of eye and orbit
0.751 0.249 0.000
I33 Acute and subacute endocarditis
0.750 0.250 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.750 0.250 0.000
F99-F99 Unspecified mental disorder
0.749 0.251 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.748 0.252 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.747 0.253 0.000
S50 Superficial injury of forearm
0.747 0.253 0.000
F60 Specific personality disorders
0.746 0.254 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.746 0.254 0.000
V80-V89 Other land transport accidents
0.746 0.254 0.000
I45 Other conduction disorders
0.746 0.254 0.000
S10-S19 Injuries to the neck
0.745 0.255 0.000
G70-G73 Diseases of myoneural junction and muscle
0.745 0.255 0.000
F41.9 Anxiety disorder, unspecified
0.744 0.256 0.000
Y48 Anaesthetics and therapeutic gases
0.744 0.256 0.000
S52.00 Fracture of upper end of ulna (closed)
0.743 0.257 0.000
S82 Fracture of lower leg, including ankle
0.743 0.257 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.742 0.258 0.000
M24.5 Contracture of joint
0.742 0.258 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.742 0.258 0.000
M21 Other acquired deformities of limbs
0.741 0.259 0.000
S56 Injury of muscle and tendon at forearm level
0.740 0.260 0.000
I47.1 Supraventricular tachycardia
0.740 0.260 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.739 0.261 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.738 0.262 0.000
I38 Endocarditis, valve unspecified
0.736 0.264 0.000
H25-H28 Disorders of lens
0.736 0.264 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.735 0.265 0.000
Y95 Nosocomial condition
0.735 0.265 0.000
M23.8 Other internal derangements of knee
0.735 0.265 0.000
M00-M03 Infectious arthropathies
0.733 0.267 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.733 0.267 0.000
S67 Crushing injury of wrist and hand
0.733 0.267 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.729 0.271 0.000
H10-H13 Disorders of conjunctiva
0.727 0.273 0.000
T87.4 Infection of amputation stump
0.726 0.274 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.726 0.274 0.000
I71 Aortic aneurysm and dissection
0.725 0.275 0.000
Y04 Assault by bodily force
0.725 0.275 0.000
M89.9 Disorder of bone, unspecified
0.725 0.275 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.724 0.275 0.000
M91-M94 Chondropathies
0.724 0.276 0.000
S60 Superficial injury of wrist and hand
0.724 0.276 0.000
L40.0 Psoriasis vulgaris
0.724 0.276 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.724 0.276 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.723 0.277 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.723 0.277 0.000
G57 Mononeuropathies of lower limb
0.723 0.277 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.721 0.279 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.721 0.279 0.000
I50.0 Congestive heart failure
0.718 0.282 0.000
M24.1 Other articular cartilage disorders
0.717 0.283 0.000
S62 Fracture at wrist and hand level
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
L10-L14 Bullous disorders
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M34 Systemic sclerosis
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.717 0.283 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.717 0.283 0.000
L94 Other localised connective tissue disorders
0.717 0.283 0.000
L87 Transepidermal elimination disorders
0.717 0.283 0.000
L88 Pyoderma gangrenosum
0.717 0.283 0.000
L86 Keratoderma in diseases classified elsewhere
0.717 0.283 0.000
L80 Vitiligo
0.717 0.283 0.000
I44.6 Other and unspecified fascicular block
0.717 0.283 0.000
L93 Lupus erythematosus
0.716 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.283 0.000
F70-F79 Mental retardation
0.716 0.283 0.000
S64 Injury of nerves at wrist and hand level
0.716 0.284 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.715 0.284 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.715 0.284 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.715 0.284 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.715 0.284 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.715 0.284 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.715 0.284 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.715 0.284 0.000
F11 Mental and behavioural disorders due to use of opioids
0.715 0.284 0.000
I77 Other disorders of arteries and arterioles
0.715 0.285 0.000
S08 Traumatic amputation of part of head
0.714 0.286 0.000
S07 Crushing injury of head
0.714 0.286 0.000
S04 Injury of cranial nerves
0.714 0.286 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
Y45.0 Opioids and related analgesics
0.713 0.287 0.000
V20-V29 Motorcycle rider injured in transport accident
0.713 0.287 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.713 0.287 0.000
G54 Nerve root and plexus disorders
0.712 0.288 0.000
F17.9 Unspecified mental and behavioural disorder
0.711 0.289 0.000
F17.8 Other mental and behavioural disorders
0.711 0.289 0.000
F17.7 Residual and late-onset psychotic disorder
0.711 0.289 0.000
F17.6 Amnesic syndrome
0.711 0.289 0.000
F17.5 Psychotic disorder
0.711 0.289 0.000
F17.4 Withdrawal state with delirium
0.711 0.289 0.000
F17.3 Withdrawal state
0.711 0.289 0.000
F17.0 Acute intoxication
0.711 0.289 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
I36 Nonrheumatic tricuspid valve disorders
0.710 0.290 0.000
G50 Disorders of trigeminal nerve
0.708 0.292 0.000
S51.0 Open wound of elbow
0.708 0.292 0.000
L81 Other disorders of pigmentation
0.708 0.292 0.000
H53-H54 Visual disturbances and blindness
0.708 0.292 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.707 0.293 0.000
W18 Other fall on same level
0.706 0.294 0.000
I44.1 Atrioventricular block, second degree
0.706 0.294 0.000
H55-H59 Other disorders of eye and adnexa
0.706 0.294 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.705 0.295 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.705 0.295 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.705 0.295 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.705 0.295 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.705 0.295 0.000
T36 Poisoning by systemic antibiotics
0.705 0.295 0.000
G95 Other diseases of spinal cord
0.704 0.296 0.000
L90.9 Atrophic disorder of skin, unspecified
0.703 0.296 0.000
L90.8 Other atrophic disorders of skin
0.703 0.296 0.000
L90.6 Striae atrophicae
0.703 0.296 0.000
L90.4 Acrodermatitis chronica atrophicans
0.703 0.296 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.703 0.296 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.703 0.296 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.703 0.296 0.000
M25.8 Other specified joint disorders
0.703 0.296 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.703 0.297 0.000
Chapter VIII Diseases of the ear and mastoid process
0.702 0.298 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.700 0.300 0.000
W13 Fall from, out of or through building or structure
0.700 0.300 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.700 0.300 0.000
M79.7 Fibromyalgia
0.699 0.301 0.000
F80-F89 Disorders of psychological development
0.698 0.302 0.000
M50-M54 Other dorsopathies
0.698 0.302 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.698 0.302 0.000
M23.9 Internal derangement of knee, unspecified
0.698 0.302 0.000
M23.1 Discoid meniscus (congenital)
0.698 0.302 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.697 0.303 0.000
Y59 Other and unspecified vaccines and biological substances
0.696 0.304 0.000
Y58 Bacterial vaccines
0.696 0.304 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.696 0.304 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.696 0.304 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.696 0.304 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.696 0.304 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.696 0.304 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.696 0.304 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.696 0.304 0.000
S59 Other and unspecified injuries of forearm
0.696 0.304 0.000
S58 Traumatic amputation of forearm
0.696 0.304 0.000
S57 Crushing injury of forearm
0.696 0.304 0.000
S55 Injury of blood vessels at forearm level
0.696 0.304 0.000
S54 Injury of nerves at forearm level
0.696 0.304 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.696 0.304 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.695 0.305 0.000
S09.8 Other specified injuries of head
0.695 0.305 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.694 0.306 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.693 0.306 0.000
S00.4 Superficial injury of ear
0.692 0.308 0.000
X60-X84 Intentional self-harm
0.692 0.308 0.000
M67.8 Other specified disorders of synovium and tendon
0.692 0.308 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.692 0.308 0.000
S82.8 Fractures of other parts of lower leg
0.690 0.310 0.000
M87 Osteonecrosis
0.690 0.310 0.000
M67.1 Other contracture of tendon (sheath)
0.690 0.310 0.000
M23.5 Chronic instability of knee
0.690 0.310 0.000
V10-V19 Pedal cyclist injured in transport accident
0.690 0.310 0.000
S68 Traumatic amputation of wrist and hand
0.689 0.311 0.000
L44 Other papulosquamous disorders
0.689 0.311 0.000
L41 Parapsoriasis
0.689 0.311 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.689 0.311 0.000
L42 Pityriasis rosea
0.689 0.311 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.689 0.311 0.000
M25.9 Joint disorder, unspecified
0.687 0.313 0.000
M25.2 Flail joint
0.687 0.313 0.000
M25.1 Fistula of joint
0.687 0.313 0.000
M25.0 Haemarthrosis
0.687 0.313 0.000
S06.4 Epidural haemorrhage
0.686 0.313 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.686 0.314 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.686 0.314 0.000
M71 Other bursopathies
0.685 0.315 0.000
M47 Spondylosis
0.685 0.315 0.000
I47.2 Ventricular tachycardia
0.684 0.316 0.000
S69 Other and unspecified injuries of wrist and hand
0.684 0.316 0.000
T66-T78 Other and unspecified effects of external causes
0.684 0.316 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.684 0.316 0.000
M25.59 Pain in joint (Site unspecified)
0.684 0.316 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.683 0.317 0.000
H18 Other disorders of cornea
0.683 0.317 0.000
S72 Fracture of femur
0.683 0.317 0.000
I00-I02 Acute rheumatic fever
0.683 0.317 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.683 0.317 0.000
G93 Other disorders of brain
0.682 0.317 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.682 0.318 0.000
I52 Other heart disorders in diseases classified elsewhere
0.681 0.319 0.000
I48 Atrial fibrillation and flutter
0.681 0.319 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.681 0.319 0.000
I41 Myocarditis in diseases classified elsewhere
0.681 0.319 0.000
I40 Acute myocarditis
0.681 0.319 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.681 0.319 0.000
I37 Pulmonary valve disorders
0.681 0.319 0.000
I32 Pericarditis in diseases classified elsewhere
0.681 0.319 0.000
F10.9 Unspecified mental and behavioural disorder
0.681 0.319 0.000
F10.8 Other mental and behavioural disorders
0.681 0.319 0.000
F10.7 Residual and late-onset psychotic disorder
0.681 0.319 0.000
F10.6 Amnesic syndrome
0.681 0.319 0.000
F10.5 Psychotic disorder
0.681 0.319 0.000
I30 Acute pericarditis
0.680 0.320 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.679 0.320 0.000
W19.1 Residential institution
0.679 0.321 0.000
I78 Diseases of capillaries
0.678 0.322 0.000
T43.2 Other and unspecified antidepressants
0.677 0.323 0.000
S52.8 Fracture of other parts of forearm
0.676 0.324 0.000
I51.7 Cardiomegaly
0.676 0.324 0.000
M20.3 Other deformity of hallux (acquired)
0.676 0.324 0.000
S00.7 Multiple superficial injuries of head
0.676 0.324 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.674 0.326 0.000
S90 Superficial injury of ankle and foot
0.674 0.326 0.000
L40.8 Other psoriasis
0.673 0.327 0.000
L40.4 Guttate psoriasis
0.673 0.327 0.000
L40.3 Pustulosis palmaris et plantaris
0.673 0.327 0.000
L40.2 Acrodermatitis continua
0.673 0.327 0.000
L40.1 Generalised pustular psoriasis
0.673 0.327 0.000
M25.52 Pain in joint (Upper arm)
0.673 0.327 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.673 0.327 0.000
S06.9 Intracranial injury, unspecified
0.672 0.328 0.000
M79.1 Myalgia
0.671 0.328 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.670 0.330 0.000
M66 Spontaneous rupture of synovium and tendon
0.670 0.330 0.000
H43-H45 Disorders of vitreous body and globe
0.670 0.330 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.670 0.330 0.000
W06 Fall involving bed
0.670 0.330 0.000
S91 Open wound of ankle and foot
0.670 0.330 0.000
W07 Fall involving chair
0.669 0.331 0.000
M88 Paget's disease of bone [osteitis deformans]
0.669 0.331 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.668 0.332 0.000
M24.9 Joint derangement, unspecified
0.668 0.332 0.000
M24.7 Protrusio acetabuli
0.668 0.332 0.000
M24.6 Ankylosis of joint
0.668 0.332 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.668 0.332 0.000
M24.0 Loose body in joint
0.668 0.332 0.000
Y40 Systemic antibiotics
0.667 0.333 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.667 0.333 0.000
S02.5 Fracture of tooth
0.667 0.333 0.000
M79.2 Neuralgia and neuritis, unspecified
0.666 0.334 0.000
M25.37 Other instability of joint (Ankle and foot)
0.666 0.334 0.000
M86 Osteomyelitis
0.666 0.334 0.000
M90 Osteopathies in diseases classified elsewhere
0.666 0.334 0.000
Y42.5 Other oestrogens and progestogens
0.666 0.334 0.000
S06.3 Focal brain injury
0.666 0.334 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.666 0.334 0.000
V48 Car occupant injured in noncollision transport accident
0.664 0.336 0.000
G96 Other disorders of central nervous system
0.664 0.336 0.000
Y54.3 Benzothiadiazine derivatives
0.664 0.336 0.000
M20.4 Other hammer toe(s) (acquired)
0.663 0.337 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.662 0.338 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.662 0.338 0.000
M20.5 Other deformities of toe(s) (acquired)
0.662 0.338 0.000
S00.3 Superficial injury of nose
0.661 0.338 0.000
L91 Hypertrophic disorders of skin
0.661 0.339 0.000
M76 Enthesopathies of lower limb, excluding foot
0.659 0.340 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.659 0.341 0.000
M23.4 Loose body in knee
0.659 0.341 0.000
S01 Open wound of head
0.658 0.341 0.000
I34 Nonrheumatic mitral valve disorders
0.658 0.342 0.000
M25.53 Pain in joint (Forearm)
0.658 0.342 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.658 0.342 0.000
M20.0 Deformity of finger(s)
0.658 0.342 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.658 0.342 0.000
W17 Other fall from one level to another
0.658 0.342 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.658 0.342 0.000
W15 Fall from cliff
0.658 0.342 0.000
W14 Fall from tree
0.658 0.342 0.000
W12 Fall on and from scaffolding
0.658 0.342 0.000
W11 Fall on and from ladder
0.658 0.342 0.000
W10 Fall on and from stairs and steps
0.658 0.342 0.000
W09 Fall involving playground equipment
0.658 0.342 0.000
W08 Fall involving other furniture
0.658 0.342 0.000
W05 Fall involving wheelchair
0.658 0.342 0.000
W04 Fall while being carried or supported by other persons
0.658 0.342 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.658 0.342 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.658 0.342 0.000
W00 Fall on same level involving ice and snow
0.658 0.342 0.000
Y54.5 Other diuretics
0.657 0.343 0.000
S52.9 Fracture of forearm, part unspecified
0.656 0.344 0.000
S52.7 Multiple fractures of forearm
0.656 0.344 0.000
S52.4 Fracture of shafts of both ulna and radius
0.656 0.344 0.000
S52.3 Fracture of shaft of radius
0.656 0.344 0.000
S52.2 Fracture of shaft of ulna
0.656 0.344 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.656 0.344 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.656 0.344 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.656 0.344 0.000
T42.3 Barbiturates
0.656 0.344 0.000
T42.2 Succinimides and oxazolidinediones
0.656 0.344 0.000
T42.1 Iminostilbenes
0.656 0.344 0.000
T42.0 Hydantoin derivatives
0.656 0.344 0.000
I45.6 Preexcitation syndrome
0.656 0.344 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.655 0.345 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.653 0.347 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.653 0.347 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.653 0.347 0.000
L89.1 Stage II decubitus ulcer
0.652 0.348 0.000
M84 Disorders of continuity of bone
0.651 0.349 0.000
S65 Injury of blood vessels at wrist and hand level
0.650 0.350 0.000
I50.9 Heart failure, unspecified
0.650 0.350 0.000
Y57.5 X-ray contrast media
0.649 0.351 0.000
S06.5 Traumatic subdural haemorrhage
0.648 0.351 0.000
S09.7 Multiple injuries of head
0.648 0.352 0.000
S09.2 Traumatic rupture of ear drum
0.648 0.352 0.000
S09.1 Injury of muscle and tendon of head
0.648 0.352 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.648 0.352 0.000
M23.37 Other meniscus derangements-Capsular lig
0.647 0.353 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.647 0.353 0.000
I47.0 Reentry ventricular arrhythmia
0.646 0.354 0.000
S92 Fracture of foot, except ankle
0.646 0.354 0.000
L53 Other erythematous conditions
0.645 0.355 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.645 0.355 0.000
T86.1 Kidney transplant failure and rejection
0.644 0.356 0.000
Y04.8 Other specified place
0.644 0.356 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.644 0.356 0.000
F41.2 Mixed anxiety and depressive disorder
0.643 0.357 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.642 0.358 0.000
M25.4 Effusion of joint
0.642 0.358 0.000
G30-G32 Other degenerative diseases of the nervous system
0.641 0.359 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.641 0.359 0.000
M05-M14 Inflammatory polyarthropathies
0.640 0.359 0.000
W19.2 School, other institution and public administrative area
0.640 0.359 0.000
F60.3 Emotionally unstable personality disorder
0.640 0.360 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.638 0.362 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.637 0.363 0.000
I72 Other aneurysm
0.636 0.364 0.000
I74 Arterial embolism and thrombosis
0.636 0.364 0.000
S51.8 Open wound of other parts of forearm
0.635 0.365 0.000
M85 Other disorders of bone density and structure
0.634 0.366 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.633 0.367 0.000
S02.1 Fracture of base of skull
0.632 0.368 0.000
M25.7 Osteophyte
0.632 0.368 0.000
I05-I09 Chronic rheumatic heart diseases
0.631 0.369 0.000
G95.8 Other specified diseases of spinal cord
0.629 0.371 0.000
F03 Unspecified dementia
0.628 0.372 0.000
I73 Other peripheral vascular diseases
0.628 0.372 0.000
G51.9 Disorder of facial nerve, unspecified
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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