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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117134709
log Bayes Factor = 14.2154
Chromosome 10   position 99,843,767  (GRCh37) Explore rs117134709 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E11.9 Without complications
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.992 0.008 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.990 0.010 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.989 0.011 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.985 0.015 0.000
Chapter IX Diseases of the circulatory system
0.976 0.024 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.976 0.024 0.000
I30-I52 Other forms of heart disease
0.975 0.025 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.974 0.026 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.971 0.029 0.000
M05-M14 Inflammatory polyarthropathies
0.968 0.032 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.968 0.032 0.000
I51 Complications and ill-defined descriptions of heart disease
0.966 0.034 0.000
E70-E90 Metabolic disorders
0.958 0.042 0.000
Y43 Primarily systemic agents
0.957 0.043 0.000
S70-S79 Injuries to the hip and thigh
0.954 0.046 0.000
S00-S09 Injuries to the head
0.947 0.053 0.000
Chapter V Mental and behavioural disorders
0.944 0.056 0.000
I51.7 Cardiomegaly
0.942 0.058 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.940 0.060 0.000
S40-S49 Injuries to the shoulder and upper arm
0.938 0.062 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.936 0.064 0.000
Y43.3 Other antineoplastic drugs
0.932 0.068 0.000
Chapter VI Diseases of the nervous system
0.930 0.070 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.929 0.071 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.924 0.076 0.000
Chapter XIV Diseases of the genitourinary system
0.922 0.078 0.000
E11.3 With ophthalmic complications
0.919 0.081 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.915 0.085 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.914 0.086 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.911 0.089 0.000
M06 Other rheumatoid arthritis
0.906 0.094 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.901 0.099 0.000
Chapter VIII Diseases of the ear and mastoid process
0.901 0.099 0.000
S09 Other and unspecified injuries of head
0.899 0.101 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.897 0.103 0.000
M45-M49 Spondylopathies
0.897 0.103 0.000
I46 Cardiac arrest
0.897 0.103 0.000
E11.2 With renal complications
0.896 0.104 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.892 0.108 0.000
I51.9 Heart disease, unspecified
0.892 0.108 0.000
L50-L54 Urticaria and erythema
0.891 0.109 0.000
O00-O08 Pregnancy with abortive outcome
0.889 0.111 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.887 0.113 0.000
D68 Other coagulation defects
0.887 0.113 0.000
L90 Atrophic disorders of skin
0.885 0.115 0.000
D50-D53 Nutritional anaemias
0.876 0.124 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.875 0.125 0.000
S09.9 Unspecified injury of head
0.865 0.135 0.000
M13 Other arthritis
0.863 0.137 0.000
D70 Agranulocytosis
0.862 0.138 0.000
E10 Insulin-dependent diabetes mellitus
0.862 0.138 0.000
S42 Fracture of shoulder and upper arm
0.862 0.138 0.000
G90-G99 Other disorders of the nervous system
0.859 0.141 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.858 0.142 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.857 0.143 0.000
Chapter XI Diseases of the digestive system
0.857 0.143 0.000
X50-X57 Overexertion, travel and privation
0.853 0.147 0.000
G62 Other polyneuropathies
0.850 0.150 0.000
O02 Other abnormal products of conception
0.850 0.150 0.000
S70 Superficial injury of hip and thigh
0.848 0.152 0.000
I44 Atrioventricular and left bundle-branch block
0.848 0.152 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.848 0.152 0.000
M06.9 Rheumatoid arthritis, unspecified
0.843 0.157 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.842 0.158 0.000
E86 Volume depletion
0.841 0.159 0.000
M50-M54 Other dorsopathies
0.840 0.160 0.000
K70-K77 Diseases of liver
0.840 0.160 0.000
L50 Urticaria
0.839 0.161 0.000
I46.0 Cardiac arrest with successful resuscitation
0.839 0.161 0.000
V10-V19 Pedal cyclist injured in transport accident
0.838 0.162 0.000
M80-M85 Disorders of bone density and structure
0.837 0.163 0.000
S42.2 Fracture of upper end of humerus
0.834 0.166 0.000
T39.1 4-Aminophenol derivatives
0.832 0.168 0.000
E11.6 With other specified complications
0.832 0.168 0.000
I42 Cardiomyopathy
0.831 0.169 0.000
N76 Other inflammation of vagina and vulva
0.830 0.170 0.000
I47 Paroxysmal tachycardia
0.828 0.172 0.000
L90.5 Scar conditions and fibrosis of skin
0.827 0.173 0.000
F30-F39 Mood [affective] disorders
0.821 0.179 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.821 0.179 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.820 0.180 0.000
D68.9 Coagulation defect, unspecified
0.820 0.180 0.000
M48 Other spondylopathies
0.819 0.181 0.000
E88 Other metabolic disorders
0.818 0.182 0.000
N25-N29 Other disorders of kidney and ureter
0.816 0.184 0.000
S42.20 Fracture of upper end of humerus (closed)
0.814 0.186 0.000
K76 Other diseases of liver
0.810 0.190 0.000
I78 Diseases of capillaries
0.809 0.191 0.000
O02.1 Missed abortion
0.808 0.192 0.000
N72 Inflammatory disease of cervix uteri
0.805 0.195 0.000
N00-N08 Glomerular diseases
0.804 0.196 0.000
E11.4 With neurological complications
0.804 0.196 0.000
W20-W49 Exposure to inanimate mechanical forces
0.801 0.199 0.000
Y45.5 4-Aminophenol derivatives
0.799 0.201 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.798 0.202 0.000
E11.5 With peripheral circulatory complications
0.797 0.203 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.796 0.204 0.000
M65-M68 Disorders of synovium and tendon
0.795 0.205 0.000
D75 Other diseases of blood and blood-forming organs
0.791 0.209 0.000
Y45.8 Other analgesics and antipyretics
0.789 0.211 0.000
H80-H83 Diseases of inner ear
0.789 0.211 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.789 0.211 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.788 0.212 0.000
M54 Dorsalgia
0.788 0.212 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.788 0.212 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.787 0.213 0.000
N10-N16 Renal tubulo-interstitial diseases
0.786 0.214 0.000
E14 Unspecified diabetes mellitus
0.785 0.215 0.000
S80-S89 Injuries to the knee and lower leg
0.784 0.216 0.000
T79-T79 Certain early complications of trauma
0.783 0.217 0.000
Chapter I Certain infectious and parasitic diseases
0.783 0.217 0.000
S71 Open wound of hip and thigh
0.782 0.218 0.000
E10.9 Without complications
0.781 0.219 0.000
M13.9 Arthritis, unspecified
0.777 0.223 0.000
G62.9 Polyneuropathy, unspecified
0.777 0.223 0.000
S72 Fracture of femur
0.775 0.225 0.000
E78.0 Pure hypercholesterolaemia
0.775 0.225 0.000
K40-K46 Hernia
0.774 0.226 0.000
X60-X84 Intentional self-harm
0.773 0.227 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.772 0.228 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.772 0.228 0.000
L84 Corns and callosities
0.768 0.232 0.000
T66-T78 Other and unspecified effects of external causes
0.765 0.235 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.765 0.235 0.000
M48.0 Spinal stenosis
0.763 0.237 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.762 0.238 0.000
H60-H62 Diseases of external ear
0.762 0.238 0.000
I74 Arterial embolism and thrombosis
0.761 0.239 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.760 0.240 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.760 0.240 0.000
D50 Iron deficiency anaemia
0.760 0.240 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.759 0.241 0.000
G61 Inflammatory polyneuropathy
0.758 0.242 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.757 0.243 0.000
M54.5 Low back pain
0.757 0.243 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.756 0.244 0.000
M10 Gout
0.756 0.244 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.753 0.246 0.000
S79 Other and unspecified injuries of hip and thigh
0.753 0.247 0.000
K74 Fibrosis and cirrhosis of liver
0.752 0.248 0.000
S70.1 Contusion of thigh
0.750 0.250 0.000
I50 Heart failure
0.750 0.250 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.750 0.250 0.000
E20-E35 Disorders of other endocrine glands
0.749 0.251 0.000
Y52 Agents primarily affecting the cardiovascular system
0.748 0.252 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.747 0.253 0.000
M14 Arthropathies in other diseases classified elsewhere
0.746 0.254 0.000
L20-L30 Dermatitis and eczema
0.742 0.258 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.742 0.258 0.000
G93 Other disorders of brain
0.741 0.259 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.741 0.259 0.000
G62.8 Other specified polyneuropathies
0.740 0.260 0.000
V80-V89 Other land transport accidents
0.740 0.260 0.000
L50.0 Allergic urticaria
0.738 0.262 0.000
M54.59 Low back pain (Site unspecified)
0.737 0.263 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.737 0.263 0.000
L82 Seborrhoeic keratosis
0.737 0.263 0.000
L89 Decubitus ulcer
0.737 0.263 0.000
I42.9 Cardiomyopathy, unspecified
0.736 0.264 0.000
M60-M63 Disorders of muscles
0.735 0.264 0.000
I44.3 Other and unspecified atrioventricular block
0.734 0.266 0.000
Chapter XXII Codes for special purposes
0.734 0.266 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.734 0.266 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.733 0.267 0.000
F60-F69 Disorders of adult personality and behaviour
0.731 0.269 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.731 0.269 0.000
F33 Recurrent depressive disorder
0.730 0.270 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.730 0.270 0.000
M48.06 Spinal stenosis (Lumbar region)
0.729 0.271 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.728 0.272 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.728 0.272 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.727 0.273 0.000
W00-W19 Falls
0.727 0.273 0.000
K44 Diaphragmatic hernia
0.727 0.273 0.000
I78.1 Naevus, nonneoplastic
0.727 0.273 0.000
Y45.1 Salicylates
0.726 0.274 0.000
S06 Intracranial injury
0.725 0.275 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.725 0.275 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.725 0.275 0.000
M84 Disorders of continuity of bone
0.725 0.275 0.000
N71 Inflammatory disease of uterus, except cervix
0.724 0.276 0.000
H81 Disorders of vestibular function
0.724 0.276 0.000
D73 Diseases of spleen
0.724 0.276 0.000
G30-G32 Other degenerative diseases of the nervous system
0.723 0.276 0.000
K76.9 Liver disease, unspecified
0.723 0.277 0.000
E13 Other specified diabetes mellitus
0.723 0.277 0.000
M06.0 Seronegative rheumatoid arthritis
0.722 0.278 0.000
T51 Toxic effect of alcohol
0.720 0.280 0.000
I44.0 Atrioventricular block, first degree
0.719 0.281 0.000
S05 Injury of eye and orbit
0.718 0.282 0.000
S02 Fracture of skull and facial bones
0.718 0.282 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E11.8 With unspecified complications
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E11.1 With ketoacidosis
0.717 0.283 0.000
E11.0 With coma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.716 0.284 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.716 0.284 0.000
K81 Cholecystitis
0.715 0.284 0.000
S40 Superficial injury of shoulder and upper arm
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.714 0.286 0.000
L40-L45 Papulosquamous disorders
0.714 0.286 0.000
I70 Atherosclerosis
0.713 0.287 0.000
Y44 Agents primarily affecting blood constituents
0.712 0.288 0.000
Y59 Other and unspecified vaccines and biological substances
0.711 0.288 0.000
Y58 Bacterial vaccines
0.711 0.288 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.711 0.288 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.288 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.711 0.288 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.711 0.288 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.711 0.288 0.000
Y48 Anaesthetics and therapeutic gases
0.711 0.288 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.711 0.288 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.711 0.288 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.711 0.288 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.711 0.289 0.000
D68.5 Primary Thrombophilia
0.711 0.289 0.000
Y45.0 Opioids and related analgesics
0.710 0.290 0.000
D55-D59 Haemolytic anaemias
0.710 0.290 0.000
N76.0 Acute vaginitis
0.710 0.290 0.000
X50 Overexertion and strenuous or repetitive movements
0.709 0.291 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.709 0.291 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.709 0.291 0.000
I45 Other conduction disorders
0.709 0.291 0.000
N20-N23 Urolithiasis
0.708 0.292 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.708 0.292 0.000
L10-L14 Bullous disorders
0.706 0.294 0.000
S32 Fracture of lumbar spine and pelvis
0.705 0.295 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.705 0.295 0.000
M86-M90 Other osteopathies
0.705 0.295 0.000
M05 Seropositive rheumatoid arthritis
0.705 0.295 0.000
I72 Other aneurysm
0.703 0.297 0.000
O21 Excessive vomiting in pregnancy
0.703 0.297 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.703 0.297 0.000
S90-S99 Injuries to the ankle and foot
0.702 0.298 0.000
O80-O84 Delivery
0.701 0.299 0.000
O20 Haemorrhage in early pregnancy
0.701 0.299 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.701 0.299 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.701 0.299 0.000
D51 Vitamin B12 deficiency anaemia
0.700 0.300 0.000
M11 Other crystal arthropathies
0.700 0.300 0.000
I00-I02 Acute rheumatic fever
0.700 0.300 0.000
O85-O92 Complications predominantly related to the puerperium
0.700 0.300 0.000
E78.8 Other disorders of lipoprotein metabolism
0.700 0.300 0.000
G70-G73 Diseases of myoneural junction and muscle
0.699 0.301 0.000
Y57 Other and unspecified drugs and medicaments
0.699 0.301 0.000
I52 Other heart disorders in diseases classified elsewhere
0.699 0.301 0.000
I48 Atrial fibrillation and flutter
0.699 0.301 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.699 0.301 0.000
I41 Myocarditis in diseases classified elsewhere
0.699 0.301 0.000
I40 Acute myocarditis
0.699 0.301 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.699 0.301 0.000
I37 Pulmonary valve disorders
0.699 0.301 0.000
I36 Nonrheumatic tricuspid valve disorders
0.699 0.301 0.000
I32 Pericarditis in diseases classified elsewhere
0.699 0.301 0.000
F99-F99 Unspecified mental disorder
0.699 0.301 0.000
L50.1 Idiopathic urticaria
0.699 0.301 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.698 0.302 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.698 0.302 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.698 0.302 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.698 0.302 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.698 0.302 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.698 0.302 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.698 0.302 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.698 0.302 0.000
T36 Poisoning by systemic antibiotics
0.698 0.302 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.696 0.304 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.696 0.304 0.000
L94 Other localised connective tissue disorders
0.696 0.304 0.000
L93 Lupus erythematosus
0.696 0.304 0.000
L87 Transepidermal elimination disorders
0.696 0.304 0.000
L88 Pyoderma gangrenosum
0.696 0.304 0.000
L86 Keratoderma in diseases classified elsewhere
0.696 0.304 0.000
L83 Acanthosis nigricans
0.696 0.304 0.000
L80 Vitiligo
0.696 0.304 0.000
M49 Spondylopathies in diseases classified elsewhere
0.694 0.305 0.000
M12 Other specific arthropathies
0.694 0.306 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.694 0.306 0.000
M08 Juvenile arthritis
0.694 0.306 0.000
I51.8 Other ill-defined heart diseases
0.694 0.306 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.694 0.306 0.000
Y45.4 Antirheumatics
0.694 0.306 0.000
Y45.2 Propionic acid derivatives
0.694 0.306 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.694 0.306 0.000
O04 Medical abortion
0.693 0.307 0.000
M91-M94 Chondropathies
0.693 0.307 0.000
I51.6 Cardiovascular disease, unspecified
0.693 0.307 0.000
I51.5 Myocardial degeneration
0.693 0.307 0.000
I51.4 Myocarditis, unspecified
0.693 0.307 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.693 0.307 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.693 0.307 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.693 0.307 0.000
I51.0 Cardiac septal defect, acquired
0.693 0.307 0.000
E65-E68 Obesity and other hyperalimentation
0.692 0.308 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.692 0.308 0.000
L50.9 Urticaria, unspecified
0.692 0.308 0.000
K81.1 Chronic cholecystitis
0.691 0.309 0.000
N76.6 Ulceration of vulva
0.691 0.309 0.000
N99-N99 Other disorders of the genitourinary system
0.689 0.311 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.689 0.311 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.689 0.311 0.000
O23 Infections of genito-urinary tract in pregnancy
0.689 0.311 0.000
M07 Psoriatic and enteropathic arthropathies
0.689 0.311 0.000
D50.8 Other iron deficiency anaemias
0.688 0.312 0.000
I33 Acute and subacute endocarditis
0.687 0.313 0.000
G95 Other diseases of spinal cord
0.687 0.313 0.000
E85 Amyloidosis
0.687 0.313 0.000
E84 Cystic fibrosis
0.687 0.313 0.000
E79 Disorders of purine and pyrimidine metabolism
0.687 0.313 0.000
E77 Disorders of glycoprotein metabolism
0.687 0.313 0.000
E76 Disorders of glycosaminoglycan metabolism
0.687 0.313 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.687 0.313 0.000
E74 Other disorders of carbohydrate metabolism
0.687 0.313 0.000
E73 Lactose intolerance
0.687 0.313 0.000
E72 Other disorders of amino-acid metabolism
0.687 0.313 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.687 0.313 0.000
E70 Disorders of aromatic amino-acid metabolism
0.687 0.313 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.687 0.313 0.000
T91 Sequelae of injuries of neck and trunk
0.687 0.313 0.000
Y43.9 Primarily systemic agent, unspecified
0.686 0.314 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.686 0.314 0.000
Y43.6 Enzymes, not elsewhere classified
0.686 0.314 0.000
Y43.5 Acidifying and alkalising agents
0.686 0.314 0.000
Y43.4 Immunosuppressive agents
0.686 0.314 0.000
Y43.2 Antineoplastic natural products
0.686 0.314 0.000
Y43.1 Antineoplastic antimetabolites
0.686 0.314 0.000
Y43.0 Antiallergic and antiemetic drugs
0.686 0.314 0.000
D68.0 Von Willebrand's disease
0.685 0.315 0.000
D75.1 Secondary polycythaemia
0.684 0.316 0.000
S78 Traumatic amputation of hip and thigh
0.684 0.316 0.000
S77 Crushing injury of hip and thigh
0.684 0.316 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.684 0.316 0.000
S75 Injury of blood vessels at hip and thigh level
0.684 0.316 0.000
S74 Injury of nerves at hip and thigh level
0.684 0.316 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.684 0.316 0.000
G90 Disorders of autonomic nervous system
0.682 0.318 0.000
B35-B49 Mycoses
0.682 0.318 0.000
X51 Travel and motion
0.681 0.319 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.681 0.319 0.000
M45 Ankylosing spondylitis
0.681 0.319 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.680 0.320 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.680 0.320 0.000
D68.8 Other specified coagulation defects
0.679 0.321 0.000
S08 Traumatic amputation of part of head
0.679 0.321 0.000
S07 Crushing injury of head
0.679 0.321 0.000
S04 Injury of cranial nerves
0.679 0.321 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.679 0.321 0.000
V20-V29 Motorcycle rider injured in transport accident
0.678 0.322 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.678 0.322 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.677 0.323 0.000
F80-F89 Disorders of psychological development
0.677 0.323 0.000
F70-F79 Mental retardation
0.677 0.323 0.000
T63 Toxic effect of contact with venomous animals
0.677 0.323 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.677 0.323 0.000
S72.1 Pertrochanteric fracture
0.675 0.325 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.674 0.326 0.000
O97 Death from sequelae of direct obstetric causes
0.674 0.326 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.674 0.326 0.000
O95 Obstetric death of unspecified cause
0.674 0.326 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.674 0.326 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.674 0.326 0.000
N76.2 Acute vulvitis
0.673 0.326 0.000
M40-M43 Deforming dorsopathies
0.673 0.327 0.000
I77 Other disorders of arteries and arterioles
0.673 0.327 0.000
S48 Traumatic amputation of shoulder and upper arm
0.672 0.328 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.672 0.328 0.000
S44 Injury of nerves at shoulder and upper arm level
0.672 0.328 0.000
S41 Open wound of shoulder and upper arm
0.672 0.328 0.000
S47 Crushing injury of shoulder and upper arm
0.672 0.328 0.000
H65-H75 Diseases of middle ear and mastoid
0.672 0.328 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.671 0.329 0.000
D74 Methaemoglobinaemia
0.671 0.329 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.671 0.329 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.671 0.329 0.000
I73 Other peripheral vascular diseases
0.671 0.329 0.000
T81 Complications of procedures, not elsewhere classified
0.668 0.332 0.000
K35-K38 Diseases of appendix
0.668 0.332 0.000
G93.3 Postviral fatigue syndrome
0.668 0.332 0.000
I47.0 Reentry ventricular arrhythmia
0.668 0.332 0.000
K74.3 Primary biliary cirrhosis
0.668 0.332 0.000
L85 Other epidermal thickening
0.667 0.332 0.000
S01 Open wound of head
0.666 0.334 0.000
D67 Hereditary factor IX deficiency
0.666 0.334 0.000
D66 Hereditary factor VIII deficiency
0.666 0.334 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.666 0.334 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.666 0.334 0.000
D60-D64 Aplastic and other anaemias
0.665 0.334 0.000
S20-S29 Injuries to the thorax
0.665 0.335 0.000
I30 Acute pericarditis
0.665 0.335 0.000
L81 Other disorders of pigmentation
0.665 0.335 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.664 0.336 0.000
N70 Salpingitis and oophoritis
0.664 0.336 0.000
G91 Hydrocephalus
0.664 0.336 0.000
E10.5 With peripheral circulatory complications
0.663 0.337 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.663 0.337 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.662 0.338 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.662 0.338 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.660 0.340 0.000
I35 Nonrheumatic aortic valve disorders
0.659 0.341 0.000
S71.1 Open wound of thigh
0.659 0.341 0.000
I47.2 Ventricular tachycardia
0.658 0.341 0.000
D69 Purpura and other haemorrhagic conditions
0.657 0.343 0.000
H61 Other disorders of external ear
0.656 0.344 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.656 0.344 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.656 0.344 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.656 0.344 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.656 0.344 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.656 0.344 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.656 0.344 0.000
E14.9 Without complications
0.655 0.344 0.000
I74.5 Embolism and thrombosis of iliac artery
0.654 0.346 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.654 0.346 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.653 0.346 0.000
T39.4 Antirheumatics, not elsewhere classified
0.653 0.346 0.000
T39.2 Pyrazolone derivatives
0.653 0.346 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.653 0.347 0.000
T43.2 Other and unspecified antidepressants
0.652 0.348 0.000
D80-D89 Certain disorders involving the immune mechanism
0.651 0.348 0.000
F30 Manic episode
0.651 0.349 0.000
I50.9 Heart failure, unspecified
0.650 0.350 0.000
I44.1 Atrioventricular block, second degree
0.650 0.350 0.000
M06.8 Other specified rheumatoid arthritis
0.649 0.351 0.000
M06.4 Inflammatory polyarthropathy
0.649 0.351 0.000
M06.3 Rheumatoid nodule
0.649 0.351 0.000
M06.2 Rheumatoid bursitis
0.649 0.351 0.000
M06.1 Adult-onset Still's disease
0.649 0.351 0.000
I46.9 Cardiac arrest, unspecified
0.649 0.351 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.649 0.351 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.649 0.351 0.000
M13.0 Polyarthritis, unspecified
0.647 0.353 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.646 0.354 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.646 0.354 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.646 0.354 0.000
L98.5 Mucinosis of skin
0.646 0.354 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.646 0.354 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.646 0.354 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.646 0.354 0.000
L98.1 Factitial dermatitis
0.646 0.354 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.646 0.354 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.645 0.355 0.000
G61.8 Other inflammatory polyneuropathies
0.645 0.355 0.000
M54.4 Lumbago with sciatica
0.645 0.355 0.000
S09.8 Other specified injuries of head
0.644 0.355 0.000
S09.7 Multiple injuries of head
0.644 0.355 0.000
S09.2 Traumatic rupture of ear drum
0.644 0.355 0.000
S09.1 Injury of muscle and tendon of head
0.644 0.355 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.644 0.355 0.000
M85 Other disorders of bone density and structure
0.644 0.356 0.000
M65 Synovitis and tenosynovitis
0.644 0.356 0.000
G60 Hereditary and idiopathic neuropathy
0.643 0.357 0.000
G64 Other disorders of peripheral nervous system
0.643 0.357 0.000
I46.1 Sudden cardiac death, so described
0.643 0.357 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.643 0.357 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.642 0.358 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.642 0.358 0.000
H81.0 Meniere's disease
0.641 0.359 0.000
D68.2 Hereditary deficiency of other clotting factors
0.641 0.359 0.000
K41 Femoral hernia
0.641 0.359 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.639 0.361 0.000
K72 Hepatic failure, not elsewhere classified
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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