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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117167356
log Bayes Factor = 12.9266
Chromosome 16   position 50,029,488  (GRCh37) Explore rs117167356 on Ensembl!
Variant rs117167356 is part of Cluster X0249

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
M50-M54 Other dorsopathies
0.998 0.002 0.000
M54 Dorsalgia
0.995 0.005 0.000
M20-M25 Other joint disorders
0.992 0.008 0.000
Chapter VII Diseases of the eye and adnexa
0.990 0.010 0.000
Chapter VI Diseases of the nervous system
0.985 0.015 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.983 0.017 0.000
R07 Pain in throat and chest
0.980 0.020 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.980 0.020 0.000
I47 Paroxysmal tachycardia
0.980 0.020 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.979 0.021 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.977 0.023 0.000
R07.4 Chest pain, unspecified
0.976 0.024 0.000
M25 Other joint disorders, not elsewhere classified
0.973 0.027 0.000
Chapter II Neoplasms
0.966 0.034 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.966 0.034 0.000
D50-D53 Nutritional anaemias
0.963 0.037 0.000
M54.5 Low back pain
0.962 0.038 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.956 0.044 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.955 0.045 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.952 0.048 0.000
I50 Heart failure
0.952 0.048 0.000
M45-M49 Spondylopathies
0.946 0.054 0.000
D51 Vitamin B12 deficiency anaemia
0.944 0.056 0.000
M35 Other systemic involvement of connective tissue
0.944 0.056 0.000
M25.4 Effusion of joint
0.939 0.061 0.000
C15-C26 Malignant neoplasms of digestive organs
0.939 0.061 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.936 0.064 0.000
R07.3 Other chest pain
0.935 0.065 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.934 0.066 0.000
I31 Other diseases of pericardium
0.929 0.071 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.928 0.072 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.927 0.073 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.918 0.082 0.000
H02 Other disorders of eyelid
0.912 0.088 0.000
I46 Cardiac arrest
0.911 0.089 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.909 0.091 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.907 0.093 0.000
Chapter X Diseases of the respiratory system
0.906 0.094 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.904 0.096 0.000
M35.3 Polymyalgia rheumatica
0.903 0.097 0.000
M54.3 Sciatica
0.902 0.098 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.899 0.101 0.000
I47.2 Ventricular tachycardia
0.897 0.103 0.000
H30-H36 Disorders of choroid and retina
0.897 0.103 0.000
M34 Systemic sclerosis
0.897 0.103 0.000
I47.0 Reentry ventricular arrhythmia
0.896 0.104 0.000
I51 Complications and ill-defined descriptions of heart disease
0.895 0.105 0.000
I73 Other peripheral vascular diseases
0.894 0.106 0.000
M25.46 Effusion of joint (Lower leg)
0.892 0.108 0.000
I45 Other conduction disorders
0.892 0.108 0.000
C20 Malignant neoplasm of rectum
0.891 0.109 0.000
S40-S49 Injuries to the shoulder and upper arm
0.887 0.113 0.000
I34 Nonrheumatic mitral valve disorders
0.886 0.114 0.000
Chapter XXII Codes for special purposes
0.885 0.115 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.884 0.116 0.000
T79-T79 Certain early complications of trauma
0.883 0.117 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.880 0.120 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.880 0.120 0.000
M25.7 Osteophyte
0.880 0.120 0.000
M54.4 Lumbago with sciatica
0.879 0.121 0.000
Chapter XX External causes of morbidity and mortality
0.878 0.122 0.000
M47 Spondylosis
0.878 0.122 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.877 0.123 0.000
M51 Other intervertebral disk disorders
0.876 0.124 0.000
G90-G99 Other disorders of the nervous system
0.872 0.128 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.868 0.132 0.000
M31 Other necrotising vasculopathies
0.866 0.134 0.000
H01 Other inflammation of eyelid
0.862 0.138 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.860 0.140 0.000
H02.1 Ectropion of eyelid
0.859 0.141 0.000
H35 Other retinal disorders
0.858 0.142 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.854 0.146 0.000
M54.57 Low back pain (Lumbosacral region)
0.852 0.148 0.000
I31.3 Pericardial effusion (noninflammatory)
0.851 0.149 0.000
I50.1 Left ventricular failure
0.849 0.151 0.000
I73.0 Raynaud's syndrome
0.848 0.152 0.000
M86-M90 Other osteopathies
0.845 0.155 0.000
M54.59 Low back pain (Site unspecified)
0.842 0.158 0.000
I47.1 Supraventricular tachycardia
0.837 0.163 0.000
R07.2 Precordial pain
0.834 0.166 0.000
I46.0 Cardiac arrest with successful resuscitation
0.832 0.168 0.000
S90-S99 Injuries to the ankle and foot
0.830 0.170 0.000
Z51 Other medical care
0.827 0.173 0.000
J09-J18 Influenza and pneumonia
0.825 0.175 0.000
D50 Iron deficiency anaemia
0.824 0.176 0.000
Q80-Q89 Other congenital malformations
0.824 0.176 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.824 0.176 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.824 0.176 0.000
M50 Cervical disk disorders
0.823 0.177 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.822 0.178 0.000
C85.1 B-cell lymphoma, unspecified
0.821 0.179 0.000
M48 Other spondylopathies
0.820 0.180 0.000
I34.0 Mitral (valve) insufficiency
0.818 0.182 0.000
D80-D89 Certain disorders involving the immune mechanism
0.816 0.184 0.000
Chapter VIII Diseases of the ear and mastoid process
0.816 0.184 0.000
Chapter I Certain infectious and parasitic diseases
0.813 0.187 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.812 0.188 0.000
R87 Abnormal findings in specimens from female genital organs
0.811 0.189 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.811 0.189 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.808 0.192 0.000
I50.0 Congestive heart failure
0.808 0.192 0.000
H04 Disorders of lachrymal system
0.808 0.192 0.000
Chapter XXI Factors influencing health status and contact with health services
0.807 0.193 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.806 0.194 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.805 0.195 0.000
Z51.3 Blood transfusion without reported diagnosis
0.804 0.196 0.000
M40-M43 Deforming dorsopathies
0.803 0.196 0.000
I37 Pulmonary valve disorders
0.803 0.197 0.000
M25.47 Effusion of joint (Ankle and foot)
0.801 0.199 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.799 0.201 0.000
Z51.8 Other specified medical care
0.798 0.202 0.000
M47.9 Spondylosis, unspecified
0.798 0.202 0.000
M25.77 Osteophyte (Ankle and foot)
0.798 0.202 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.797 0.203 0.000
M80-M85 Disorders of bone density and structure
0.796 0.204 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.794 0.206 0.000
I49 Other cardiac arrhythmias
0.793 0.207 0.000
C21 Malignant neoplasm of anus and anal canal
0.793 0.207 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.793 0.207 0.000
D60-D64 Aplastic and other anaemias
0.792 0.208 0.000
I45.6 Preexcitation syndrome
0.790 0.210 0.000
M65-M68 Disorders of synovium and tendon
0.789 0.211 0.000
R02 Gangrene, not elsewhere classified
0.789 0.211 0.000
E70-E90 Metabolic disorders
0.788 0.212 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.785 0.215 0.000
T17 Foreign body in respiratory tract
0.785 0.215 0.000
M31.6 Other giant cell arteritis
0.783 0.217 0.000
I50.9 Heart failure, unspecified
0.782 0.218 0.000
R00 Abnormalities of heart beat
0.781 0.219 0.000
M34.8 Other forms of systemic sclerosis
0.779 0.221 0.000
M54.1 Radiculopathy
0.778 0.222 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.777 0.222 0.000
Z51.1 Chemotherapy session for neoplasm
0.775 0.225 0.000
L90 Atrophic disorders of skin
0.774 0.226 0.000
S80-S89 Injuries to the knee and lower leg
0.773 0.227 0.000
C16 Malignant neoplasm of stomach
0.772 0.228 0.000
M54.6 Pain in thoracic spine
0.770 0.229 0.000
H01.8 Other specified inflammation of eyelid
0.770 0.230 0.000
J90-J94 Other diseases of pleura
0.770 0.230 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.769 0.231 0.000
D00-D09 In situ neoplasms
0.768 0.232 0.000
I60-I69 Cerebrovascular diseases
0.767 0.233 0.000
D50.8 Other iron deficiency anaemias
0.766 0.234 0.000
M54.55 Low back pain (Thoracolumbar region)
0.766 0.234 0.000
M54.9 Dorsalgia, unspecified
0.766 0.234 0.000
M47.2 Other spondylosis with radiculopathy
0.765 0.235 0.000
C81 Hodgkin's disease
0.765 0.235 0.000
I71 Aortic aneurysm and dissection
0.765 0.235 0.000
M25.9 Joint disorder, unspecified
0.765 0.235 0.000
Z51.2 Other chemotherapy
0.764 0.236 0.000
Z45 Adjustment and management of implanted device
0.763 0.237 0.000
E65-E68 Obesity and other hyperalimentation
0.762 0.238 0.000
M25.8 Other specified joint disorders
0.762 0.238 0.000
M05-M14 Inflammatory polyarthropathies
0.762 0.238 0.000
I51.0 Cardiac septal defect, acquired
0.761 0.239 0.000
I51.7 Cardiomegaly
0.761 0.239 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.760 0.240 0.000
L90.5 Scar conditions and fibrosis of skin
0.759 0.241 0.000
J95-J99 Other diseases of the respiratory system
0.757 0.243 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.757 0.243 0.000
I31.9 Disease of pericardium, unspecified
0.755 0.245 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.754 0.246 0.000
H02.6 Xanthelasma of eyelid
0.753 0.247 0.000
G54 Nerve root and plexus disorders
0.753 0.247 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.752 0.248 0.000
H36 Retinal disorders in diseases classified elsewhere
0.750 0.250 0.000
M34.9 Systemic sclerosis, unspecified
0.750 0.250 0.000
H43-H45 Disorders of vitreous body and globe
0.749 0.251 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.748 0.252 0.000
H02.0 Entropion and trichiasis of eyelid
0.748 0.252 0.000
M51.8 Other specified intervertebral disk disorders
0.747 0.253 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.746 0.254 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.746 0.254 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.745 0.255 0.000
H35.3 Degeneration of macula and posterior pole
0.745 0.255 0.000
H25-H28 Disorders of lens
0.744 0.256 0.000
M54.56 Low back pain (Lumbar region)
0.744 0.256 0.000
M54.37 Sciatica (Lumbosacral region)
0.744 0.256 0.000
I72 Other aneurysm
0.742 0.258 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.740 0.259 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.740 0.260 0.000
I95 Hypotension
0.740 0.260 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.739 0.261 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.739 0.261 0.000
M54.39 Sciatica (Site unspecified)
0.739 0.261 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.737 0.263 0.000
G96 Other disorders of central nervous system
0.737 0.263 0.000
E10-E14 Diabetes mellitus
0.737 0.263 0.000
I78 Diseases of capillaries
0.736 0.264 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.736 0.264 0.000
M60-M63 Disorders of muscles
0.736 0.264 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.735 0.264 0.000
S10-S19 Injuries to the neck
0.735 0.265 0.000
L91 Hypertrophic disorders of skin
0.735 0.265 0.000
M50.1 Cervical disk disorder with radiculopathy
0.735 0.265 0.000
H53-H54 Visual disturbances and blindness
0.735 0.265 0.000
H35.0 Background retinopathy and retinal vascular changes
0.735 0.265 0.000
G20-G26 Extrapyramidal and movement disorders
0.734 0.266 0.000
M54.36 Sciatica (Lumbar region)
0.734 0.266 0.000
T00-T07 Injuries involving multiple body regions
0.733 0.267 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.733 0.267 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.733 0.267 0.000
I45.9 Conduction disorder, unspecified
0.732 0.268 0.000
M24 Other specific joint derangements
0.731 0.269 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.731 0.269 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.731 0.269 0.000
I60 Subarachnoid haemorrhage
0.730 0.270 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.729 0.271 0.000
I74 Arterial embolism and thrombosis
0.729 0.271 0.000
S20-S29 Injuries to the thorax
0.728 0.272 0.000
E87.2 Acidosis
0.728 0.272 0.000
C51-C58 Malignant neoplasms of female genital organs
0.725 0.275 0.000
R87.6 Abnormal cytological findings
0.725 0.275 0.000
G70-G73 Diseases of myoneural junction and muscle
0.724 0.276 0.000
L84 Corns and callosities
0.723 0.277 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.723 0.277 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.723 0.277 0.000
S50-S59 Injuries to the elbow and forearm
0.723 0.277 0.000
H02.2 Lagophthalmos
0.722 0.278 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.722 0.278 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.721 0.279 0.000
M48.0 Spinal stenosis
0.721 0.279 0.000
J60-J70 Lung diseases due to external agents
0.721 0.279 0.000
J80 Adult respiratory distress syndrome
0.720 0.280 0.000
U80 Agent resistant to penicillin and related antibiotics
0.720 0.280 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.720 0.280 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.720 0.280 0.000
H02.8 Other specified disorders of eyelid
0.719 0.281 0.000
I35 Nonrheumatic aortic valve disorders
0.719 0.281 0.000
R05 Cough
0.718 0.282 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
G30-G32 Other degenerative diseases of the nervous system
0.716 0.284 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.716 0.284 0.000
M25.71 Osteophyte (Shoulder region)
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.713 0.286 0.000
M54.8 Other dorsalgia
0.713 0.287 0.000
M54.0 Panniculitis affecting regions of neck and back
0.713 0.287 0.000
H65-H75 Diseases of middle ear and mastoid
0.713 0.287 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.713 0.287 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.712 0.288 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.711 0.289 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.711 0.289 0.000
M33 Dermatopolymyositis
0.711 0.289 0.000
M32 Systemic lupus erythematosus
0.711 0.289 0.000
M30 Polyarteritis nodosa and related conditions
0.711 0.289 0.000
M35.7 Hypermobility syndrome
0.708 0.292 0.000
C17 Malignant neoplasm of small intestine
0.706 0.294 0.000
H05 Disorders of orbit
0.706 0.294 0.000
H60-H62 Diseases of external ear
0.705 0.295 0.000
T33-T35 Frostbite
0.705 0.295 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.705 0.295 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.705 0.295 0.000
I46.9 Cardiac arrest, unspecified
0.705 0.295 0.000
L89 Decubitus ulcer
0.704 0.296 0.000
G50 Disorders of trigeminal nerve
0.704 0.296 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.703 0.297 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.702 0.297 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.702 0.298 0.000
E83 Disorders of mineral metabolism
0.702 0.298 0.000
Z45.8 Adjustment and management of other implanted devices
0.702 0.298 0.000
S92 Fracture of foot, except ankle
0.702 0.298 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.701 0.298 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.701 0.298 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.701 0.299 0.000
Y43 Primarily systemic agents
0.701 0.299 0.000
D55-D59 Haemolytic anaemias
0.701 0.299 0.000
R07.0 Pain in throat
0.700 0.300 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.699 0.301 0.000
X60-X84 Intentional self-harm
0.699 0.301 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.698 0.302 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.698 0.302 0.000
M25.3 Other instability of joint
0.698 0.302 0.000
M25.2 Flail joint
0.698 0.302 0.000
M25.1 Fistula of joint
0.698 0.302 0.000
M25.0 Haemarthrosis
0.698 0.302 0.000
R07.1 Chest pain on breathing
0.697 0.303 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.696 0.304 0.000
W20-W49 Exposure to inanimate mechanical forces
0.695 0.305 0.000
I49.0 Ventricular fibrillation and flutter
0.695 0.305 0.000
Z54 Convalescence
0.694 0.306 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.694 0.306 0.000
Q85 Phakomatoses, not elsewhere classified
0.693 0.307 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.693 0.307 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.693 0.307 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.692 0.307 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.692 0.307 0.000
G93 Other disorders of brain
0.692 0.308 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.692 0.308 0.000
H35.9 Retinal disorder, unspecified
0.691 0.309 0.000
G58 Other mononeuropathies
0.691 0.309 0.000
Q82 Other congenital malformations of skin
0.691 0.309 0.000
D53 Other nutritional anaemias
0.691 0.309 0.000
S42 Fracture of shoulder and upper arm
0.690 0.310 0.000
J81 Pulmonary oedema
0.690 0.310 0.000
M54.54 Low back pain-Thoracic
0.690 0.310 0.000
M54.53 Low back pain-Cervicothoracic
0.690 0.310 0.000
M54.52 Low back pain-Cervical
0.690 0.310 0.000
M54.51 Low back pain-Occipit-atl-axl
0.690 0.310 0.000
M54.50 Low back pain (Multiple sites in spine)
0.690 0.310 0.000
L91.8 Other hypertrophic disorders of skin
0.689 0.311 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.689 0.311 0.000
M53 Other dorsopathies, not elsewhere classified
0.689 0.311 0.000
M51.9 Intervertebral disk disorder, unspecified
0.688 0.312 0.000
C91 Lymphoid leukaemia
0.688 0.312 0.000
M35.0 Sicca syndrome [Sjogren]
0.687 0.313 0.000
M54.12 Radiculopathy (Cervical region)
0.687 0.313 0.000
E66 Obesity
0.686 0.314 0.000
T18 Foreign body in alimentary tract
0.686 0.314 0.000
G52 Disorders of other cranial nerves
0.685 0.314 0.000
H35.5 Hereditary retinal dystrophy
0.685 0.315 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.685 0.315 0.000
C95 Leukaemia of unspecified cell type
0.685 0.315 0.000
C94 Other leukaemias of specified cell type
0.685 0.315 0.000
C93 Monocytic leukaemia
0.685 0.315 0.000
C88 Malignant immunoproliferative diseases
0.685 0.315 0.000
C86 Other specified types of T/NK-cell lymphoma
0.685 0.315 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.684 0.315 0.000
C21.0 Anus, unspecified
0.684 0.316 0.000
G57 Mononeuropathies of lower limb
0.684 0.316 0.000
R00.1 Bradycardia, unspecified
0.684 0.316 0.000
D52 Folate deficiency anaemia
0.683 0.317 0.000
M90 Osteopathies in diseases classified elsewhere
0.683 0.317 0.000
H40-H42 Glaucoma
0.683 0.317 0.000
H52 Disorders of refraction and accommodation
0.683 0.317 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.682 0.318 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.682 0.318 0.000
H04.1 Other disorders of lachrymal gland
0.682 0.318 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.682 0.318 0.000
I51.9 Heart disease, unspecified
0.681 0.319 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.681 0.319 0.000
J10 Influenza due to identified influenza virus
0.680 0.320 0.000
H31 Other disorders of choroid
0.679 0.320 0.000
W50-W64 Exposure to animate mechanical forces
0.679 0.321 0.000
M49 Spondylopathies in diseases classified elsewhere
0.678 0.321 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.677 0.323 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.677 0.323 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.677 0.323 0.000
D51.2 Transcobalamin II deficiency
0.677 0.323 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.677 0.323 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.677 0.323 0.000
M35.8 Other specified systemic involvement of connective tissue
0.677 0.323 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.677 0.323 0.000
M35.5 Multifocal fibrosclerosis
0.677 0.323 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.677 0.323 0.000
M35.2 Behcet's disease
0.677 0.323 0.000
M35.1 Other overlap syndromes
0.677 0.323 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.676 0.324 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.675 0.325 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.675 0.325 0.000
I33 Acute and subacute endocarditis
0.675 0.325 0.000
H35.2 Other proliferative retinopathy
0.675 0.325 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.674 0.326 0.000
J93 Pneumothorax
0.673 0.326 0.000
M25.49 Effusion of joint (Site unspecified)
0.673 0.327 0.000
M25.48 Effusion of joint (Other)
0.673 0.327 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.673 0.327 0.000
M25.44 Effusion of joint (Hand)
0.673 0.327 0.000
M25.43 Effusion of joint (Forearm)
0.673 0.327 0.000
M25.42 Effusion of joint (Upper arm)
0.673 0.327 0.000
M25.41 Effusion of joint (Shoulder region)
0.673 0.327 0.000
M25.40 Effusion of joint (Multiple sites)
0.673 0.327 0.000
S00-S09 Injuries to the head
0.673 0.327 0.000
T17.2 Foreign body in pharynx
0.673 0.327 0.000
C23 Malignant neoplasm of gallbladder
0.673 0.327 0.000
M91-M94 Chondropathies
0.673 0.327 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.672 0.328 0.000
B25-B34 Other viral diseases
0.672 0.328 0.000
I38 Endocarditis, valve unspecified
0.672 0.328 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.671 0.329 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.670 0.330 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.670 0.330 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.670 0.330 0.000
C85.0 Lymphosarcoma
0.670 0.330 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.669 0.331 0.000
M21 Other acquired deformities of limbs
0.668 0.332 0.000
M41 Scoliosis
0.668 0.332 0.000
R86 Abnormal findings in specimens from male genital organs
0.667 0.332 0.000
I31.8 Other specified diseases of pericardium
0.666 0.334 0.000
I31.2 Haemopericardium, not elsewhere classified
0.666 0.334 0.000
I31.1 Chronic constrictive pericarditis
0.666 0.334 0.000
I31.0 Chronic adhesive pericarditis
0.666 0.334 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.665 0.334 0.000
G91 Hydrocephalus
0.665 0.335 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.665 0.335 0.000
I51.4 Myocarditis, unspecified
0.664 0.336 0.000
M25.78 Osteophyte (Other)
0.664 0.336 0.000
I73.9 Peripheral vascular disease, unspecified
0.664 0.336 0.000
H01.0 Blepharitis
0.663 0.337 0.000
I45.3 Trifascicular block
0.662 0.337 0.000
I37.1 Pulmonary valve insufficiency
0.662 0.338 0.000
M86 Osteomyelitis
0.662 0.338 0.000
M47.1 Other spondylosis with myelopathy
0.660 0.340 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.660 0.340 0.000
H35.7 Separation of retinal layers
0.660 0.340 0.000
T79.6 Traumatic ischaemia of muscle
0.658 0.342 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.658 0.342 0.000
M45 Ankylosing spondylitis
0.658 0.342 0.000
M06 Other rheumatoid arthritis
0.657 0.343 0.000
H02.3 Blepharochalasis
0.656 0.344 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.655 0.345 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.654 0.346 0.000
E66.8 Other obesity
0.654 0.346 0.000
I46.1 Sudden cardiac death, so described
0.653 0.347 0.000
I61 Intracerebral haemorrhage
0.653 0.347 0.000
C92 Myeloid leukaemia
0.652 0.347 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.652 0.348 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.652 0.348 0.000
R83 Abnormal findings in cerebrospinal fluid
0.652 0.348 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.652 0.348 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.651 0.349 0.000
M46 Other inflammatory spondylopathies
0.651 0.349 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.651 0.349 0.000
M54.2 Cervicalgia
0.651 0.349 0.000
Q00-Q07 Congenital malformations of the nervous system
0.651 0.349 0.000
E10 Insulin-dependent diabetes mellitus
0.651 0.349 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.650 0.350 0.000
Q35-Q37 Cleft lip and cleft palate
0.650 0.350 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.650 0.350 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.650 0.350 0.000
T17.8 Foreign body in other and multiple parts of respiratory tract
0.650 0.350 0.000
S80 Superficial injury of lower leg
0.650 0.350 0.000
B65-B83 Helminthiases
0.649 0.350 0.000
H02.5 Other disorders affecting eyelid function
0.649 0.351 0.000
I70 Atherosclerosis
0.649 0.351 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.647 0.353 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.647 0.353 0.000
G61 Inflammatory polyneuropathy
0.647 0.353 0.000
R47-R49 Symptoms and signs involving speech and voice
0.647 0.353 0.000
X50-X57 Overexertion, travel and privation
0.647 0.353 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.647 0.353 0.000
M54.35 Sciatica (Thoracolumbar region)
0.647 0.353 0.000
M54.34 Sciatica-Thoracic
0.647 0.353 0.000
M54.33 Sciatica-Cervicothoracic
0.647 0.353 0.000
M54.32 Sciatica-Cervical
0.647 0.353 0.000
M54.31 Sciatica-Occipit-atl-axl
0.647 0.353 0.000
M54.30 Sciatica (Multiple sites in spine)
0.647 0.353 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.645 0.355 0.000
H36.0 Diabetic retinopathy
0.645 0.355 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.644 0.355 0.000
E87.6 Hypokalaemia
0.644 0.356 0.000
H25 Senile cataract
0.643 0.357 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.643 0.357 0.000
H30 Chorioretinal inflammation
0.643 0.357 0.000
H52.0 Hypermetropia
0.643 0.357 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.643 0.357 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.643 0.357 0.000
M34.1 CR(E)ST syndrome
0.643 0.357 0.000
M34.0 Progressive systemic sclerosis
0.643 0.357 0.000
C01 Malignant neoplasm of base of tongue
0.642 0.357 0.000
D84 Other immunodeficiencies
0.642 0.358 0.000
Y43.3 Other antineoplastic drugs
0.642 0.358 0.000
I51.6 Cardiovascular disease, unspecified
0.642 0.358 0.000
I51.5 Myocardial degeneration
0.642 0.358 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.642 0.358 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.642 0.358 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.641 0.359 0.000
I73.8 Other specified peripheral vascular diseases
0.641 0.359 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.641 0.359 0.000
L20-L30 Dermatitis and eczema
0.640 0.360 0.000
G96.0 Cerebrospinal fluid leak
0.640 0.360 0.000
I45.8 Other specified conduction disorders
0.640 0.360 0.000
I45.4 Nonspecific intraventricular block
0.640 0.360 0.000
I45.2 Bifascicular block
0.640 0.360 0.000
I45.0 Right fascicular block
0.640 0.360 0.000
G90 Disorders of autonomic nervous system
0.640 0.360 0.000
Q89 Other congenital malformations, not elsewhere classified
0.639 0.361 0.000
Q60-Q64 Congenital malformations of the urinary system
0.639 0.361 0.000
J94 Other pleural conditions
0.639 0.361 0.000
G51 Facial nerve disorders
0.638 0.361 0.000
G95 Other diseases of spinal cord
0.638 0.362 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.638 0.362 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.638 0.362 0.000
M88 Paget's disease of bone [osteitis deformans]
0.637 0.363 0.000
X20-X29 Contact with venomous animals and plants
0.636 0.364 0.000
S48 Traumatic amputation of shoulder and upper arm
0.636 0.364 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.636 0.364 0.000
S44 Injury of nerves at shoulder and upper arm level
0.636 0.364 0.000
S41 Open wound of shoulder and upper arm
0.636 0.364 0.000
S47 Crushing injury of shoulder and upper arm
0.636 0.364 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.635 0.365 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.635 0.365 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.635 0.365 0.000
I05-I09 Chronic rheumatic heart diseases
0.635 0.365 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.633 0.366 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.631 0.369 0.000
H04.9 Disorder of lachrymal system, unspecified
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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