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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117167710
log Bayes Factor = 18.286
Chromosome 19   position 49,602,287  (GRCh37) Explore rs117167710 on Ensembl!
Variant rs117167710 is part of Cluster X0072

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J95-J99 Other diseases of the respiratory system
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
S00-S09 Injuries to the head
0.998 0.002 0.000
J98 Other respiratory disorders
0.997 0.003 0.000
J98.1 Pulmonary collapse
0.996 0.004 0.000
M45-M49 Spondylopathies
0.993 0.007 0.000
W00-W19 Falls
0.993 0.007 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.991 0.009 0.000
M50-M54 Other dorsopathies
0.990 0.010 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.987 0.013 0.000
J40-J47 Chronic lower respiratory diseases
0.983 0.017 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.981 0.019 0.000
I60-I69 Cerebrovascular diseases
0.976 0.024 0.000
S60-S69 Injuries to the wrist and hand
0.974 0.026 0.000
W19 Unspecified fall
0.974 0.026 0.000
M50 Cervical disk disorders
0.973 0.027 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.973 0.027 0.000
M47 Spondylosis
0.971 0.029 0.000
S09 Other and unspecified injuries of head
0.970 0.030 0.000
W19.9 Unspecified place
0.970 0.030 0.000
Y95 Nosocomial condition
0.964 0.036 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.961 0.039 0.000
M70-M79 Other soft tissue disorders
0.960 0.040 0.000
I67 Other cerebrovascular diseases
0.956 0.044 0.000
I34 Nonrheumatic mitral valve disorders
0.950 0.050 0.000
I51 Complications and ill-defined descriptions of heart disease
0.948 0.052 0.000
Chapter V Mental and behavioural disorders
0.947 0.053 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.944 0.056 0.000
R47-R49 Symptoms and signs involving speech and voice
0.940 0.060 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.939 0.061 0.000
S09.9 Unspecified injury of head
0.937 0.063 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.936 0.064 0.000
J44 Other chronic obstructive pulmonary disease
0.933 0.067 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.932 0.068 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.930 0.070 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.930 0.070 0.000
R47 Speech disturbances, not elsewhere classified
0.923 0.077 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.923 0.077 0.000
I44 Atrioventricular and left bundle-branch block
0.921 0.079 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.918 0.082 0.000
M80-M85 Disorders of bone density and structure
0.917 0.083 0.000
I67.8 Other specified cerebrovascular diseases
0.916 0.084 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.913 0.087 0.000
F10.2 Dependence syndrome
0.912 0.088 0.000
F10.0 Acute intoxication
0.911 0.089 0.000
S01 Open wound of head
0.909 0.091 0.000
M47.9 Spondylosis, unspecified
0.909 0.091 0.000
M47.8 Other spondylosis
0.907 0.093 0.000
M48 Other spondylopathies
0.905 0.095 0.000
T51 Toxic effect of alcohol
0.903 0.096 0.000
M50.1 Cervical disk disorder with radiculopathy
0.900 0.100 0.000
I38 Endocarditis, valve unspecified
0.897 0.103 0.000
S00 Superficial injury of head
0.890 0.110 0.000
S62 Fracture at wrist and hand level
0.886 0.114 0.000
S06 Intracranial injury
0.880 0.120 0.000
I51.9 Heart disease, unspecified
0.877 0.123 0.000
I45 Other conduction disorders
0.872 0.127 0.000
R47.0 Dysphasia and aphasia
0.871 0.129 0.000
T42.4 Benzodiazepines
0.870 0.130 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.868 0.132 0.000
S61 Open wound of wrist and hand
0.868 0.132 0.000
I34.0 Mitral (valve) insufficiency
0.867 0.133 0.000
T43.2 Other and unspecified antidepressants
0.867 0.133 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.864 0.136 0.000
M79.6 Pain in limb
0.863 0.137 0.000
J98.4 Other disorders of lung
0.863 0.137 0.000
J40 Bronchitis, not specified as acute or chronic
0.861 0.139 0.000
J46 Status asthmaticus
0.860 0.140 0.000
M54 Dorsalgia
0.859 0.141 0.000
I44.0 Atrioventricular block, first degree
0.854 0.146 0.000
M20-M25 Other joint disorders
0.853 0.147 0.000
I51.7 Cardiomegaly
0.852 0.148 0.000
T51.0 Ethanol
0.848 0.152 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.844 0.155 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.842 0.158 0.000
R47.8 Other and unspecified speech disturbances
0.839 0.161 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.835 0.165 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.835 0.165 0.000
M84 Disorders of continuity of bone
0.835 0.165 0.000
M48.0 Spinal stenosis
0.835 0.165 0.000
Y42.5 Other oestrogens and progestogens
0.835 0.165 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.835 0.165 0.000
M79.7 Fibromyalgia
0.833 0.167 0.000
M50.2 Other cervical disk displacement
0.830 0.170 0.000
R00 Abnormalities of heart beat
0.829 0.171 0.000
V20-V29 Motorcycle rider injured in transport accident
0.828 0.172 0.000
R00.0 Tachycardia, unspecified
0.825 0.175 0.000
I61 Intracerebral haemorrhage
0.823 0.177 0.000
M50.0 Cervical disk disorder with myelopathy
0.822 0.178 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.822 0.178 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.822 0.178 0.000
Chapter XI Diseases of the digestive system
0.821 0.179 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.821 0.179 0.000
W20-W49 Exposure to inanimate mechanical forces
0.821 0.179 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.820 0.179 0.000
M86-M90 Other osteopathies
0.819 0.181 0.000
I35 Nonrheumatic aortic valve disorders
0.817 0.183 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.817 0.183 0.000
W07 Fall involving chair
0.817 0.183 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.815 0.185 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.815 0.185 0.000
M50.3 Other cervical disk degeneration
0.814 0.186 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.812 0.188 0.000
Q21 Congenital malformations of cardiac septa
0.810 0.190 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.809 0.191 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.808 0.192 0.000
S01.0 Open wound of scalp
0.807 0.193 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.806 0.194 0.000
I67.9 Cerebrovascular disease, unspecified
0.805 0.195 0.000
J43 Emphysema
0.805 0.195 0.000
Y57 Other and unspecified drugs and medicaments
0.805 0.195 0.000
J90-J94 Other diseases of pleura
0.804 0.196 0.000
S80-S89 Injuries to the knee and lower leg
0.802 0.198 0.000
I37 Pulmonary valve disorders
0.801 0.199 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.800 0.200 0.000
S00.8 Superficial injury of other parts of head
0.800 0.200 0.000
I44.1 Atrioventricular block, second degree
0.799 0.201 0.000
M47.82 Other spondylosis (Cervical region)
0.799 0.201 0.000
S09.8 Other specified injuries of head
0.798 0.202 0.000
M48.06 Spinal stenosis (Lumbar region)
0.796 0.204 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.795 0.205 0.000
Y00-Y09 Assault
0.795 0.205 0.000
K01 Embedded and impacted teeth
0.795 0.205 0.000
S64 Injury of nerves at wrist and hand level
0.793 0.207 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.793 0.207 0.000
X20-X29 Contact with venomous animals and plants
0.791 0.209 0.000
I42 Cardiomyopathy
0.791 0.209 0.000
Y40 Systemic antibiotics
0.791 0.209 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.791 0.209 0.000
I95 Hypotension
0.790 0.210 0.000
X60-X84 Intentional self-harm
0.789 0.211 0.000
S01.3 Open wound of ear
0.788 0.212 0.000
S62.6 Fracture of other finger
0.787 0.213 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.786 0.214 0.000
V10-V19 Pedal cyclist injured in transport accident
0.786 0.214 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.784 0.216 0.000
S20-S29 Injuries to the thorax
0.782 0.218 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.781 0.219 0.000
M51 Other intervertebral disk disorders
0.781 0.219 0.000
M60-M63 Disorders of muscles
0.780 0.220 0.000
W17 Other fall from one level to another
0.780 0.220 0.000
M23 Internal derangement of knee
0.780 0.220 0.000
M91-M94 Chondropathies
0.779 0.221 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.779 0.221 0.000
M79.66 Pain in limb (Lower leg)
0.778 0.222 0.000
I36 Nonrheumatic tricuspid valve disorders
0.777 0.222 0.000
K01.1 Impacted teeth
0.777 0.223 0.000
I67.2 Cerebral atherosclerosis
0.775 0.225 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.773 0.227 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.773 0.227 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.772 0.228 0.000
Q23 Congenital malformations of aortic and mitral valves
0.772 0.228 0.000
Q00-Q07 Congenital malformations of the nervous system
0.772 0.228 0.000
F60-F69 Disorders of adult personality and behaviour
0.771 0.229 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.771 0.229 0.000
T51.9 Alcohol, unspecified
0.771 0.229 0.000
S10-S19 Injuries to the neck
0.770 0.230 0.000
X10-X19 Contact with heat and hot substances
0.769 0.231 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.768 0.232 0.000
K70-K77 Diseases of liver
0.766 0.234 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.766 0.234 0.000
R80 Isolated proteinuria
0.765 0.235 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.762 0.238 0.000
M45 Ankylosing spondylitis
0.760 0.240 0.000
J60-J70 Lung diseases due to external agents
0.760 0.240 0.000
Y43 Primarily systemic agents
0.760 0.240 0.000
W18 Other fall on same level
0.759 0.241 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.758 0.242 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.758 0.242 0.000
J42 Unspecified chronic bronchitis
0.758 0.242 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.757 0.243 0.000
M65-M68 Disorders of synovium and tendon
0.755 0.245 0.000
Y52 Agents primarily affecting the cardiovascular system
0.754 0.246 0.000
S00.1 Contusion of eyelid and periocular area
0.753 0.247 0.000
I05-I09 Chronic rheumatic heart diseases
0.753 0.247 0.000
S68 Traumatic amputation of wrist and hand
0.752 0.248 0.000
W08 Fall involving other furniture
0.752 0.248 0.000
I85 Oesophageal varices
0.752 0.248 0.000
S40-S49 Injuries to the shoulder and upper arm
0.748 0.252 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.747 0.253 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.747 0.253 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.746 0.254 0.000
I45.1 Other and unspecified right bundle-branch block
0.746 0.254 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.745 0.255 0.000
M46 Other inflammatory spondylopathies
0.745 0.255 0.000
M77 Other enthesopathies
0.743 0.257 0.000
F99-F99 Unspecified mental disorder
0.741 0.259 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.741 0.259 0.000
Chapter XXII Codes for special purposes
0.740 0.260 0.000
R02 Gangrene, not elsewhere classified
0.740 0.260 0.000
M00-M03 Infectious arthropathies
0.739 0.261 0.000
I47 Paroxysmal tachycardia
0.739 0.261 0.000
S62.3 Fracture of other metacarpal bone
0.739 0.261 0.000
M40-M43 Deforming dorsopathies
0.739 0.261 0.000
V40-V49 Car occupant injured in transport accident
0.738 0.261 0.000
W50-W64 Exposure to animate mechanical forces
0.738 0.262 0.000
I51.0 Cardiac septal defect, acquired
0.737 0.263 0.000
Q27 Other congenital malformations of peripheral vascular system
0.736 0.263 0.000
S01.4 Open wound of cheek and temporomandibular area
0.735 0.265 0.000
M23.3 Other meniscus derangements
0.735 0.265 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.734 0.266 0.000
M47.86 Other spondylosis (Lumbar region)
0.734 0.266 0.000
I80 Phlebitis and thrombophlebitis
0.734 0.266 0.000
M54.2 Cervicalgia
0.734 0.266 0.000
Q21.1 Atrial septal defect
0.733 0.267 0.000
R47.1 Dysarthria and anarthria
0.733 0.267 0.000
S70-S79 Injuries to the hip and thigh
0.733 0.267 0.000
I44.2 Atrioventricular block, complete
0.733 0.267 0.000
Y85 Sequelae of transport accidents
0.732 0.268 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.731 0.269 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.730 0.270 0.000
F80-F89 Disorders of psychological development
0.729 0.271 0.000
M21 Other acquired deformities of limbs
0.729 0.271 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.727 0.273 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.726 0.273 0.000
I33 Acute and subacute endocarditis
0.725 0.275 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.724 0.275 0.000
R23 Other skin changes
0.723 0.277 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.723 0.277 0.000
S05 Injury of eye and orbit
0.722 0.277 0.000
R45 Symptoms and signs involving emotional state
0.722 0.278 0.000
I51.4 Myocarditis, unspecified
0.722 0.278 0.000
V80-V89 Other land transport accidents
0.721 0.279 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.719 0.281 0.000
I34.1 Mitral (valve) prolapse
0.719 0.281 0.000
R82 Other abnormal findings in urine
0.718 0.282 0.000
K76 Other diseases of liver
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.716 0.284 0.000
J96 Respiratory failure, not elsewhere classified
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
S08 Traumatic amputation of part of head
0.715 0.284 0.000
S07 Crushing injury of head
0.715 0.284 0.000
S04 Injury of cranial nerves
0.715 0.284 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.715 0.284 0.000
S61.1 Open wound of finger(s) with damage to nail
0.715 0.285 0.000
M79.0 Rheumatism, unspecified
0.715 0.285 0.000
J98.9 Respiratory disorder, unspecified
0.715 0.285 0.000
J98.6 Disorders of diaphragm
0.715 0.285 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.715 0.285 0.000
J98.3 Compensatory emphysema
0.715 0.285 0.000
J98.2 Interstitial emphysema
0.715 0.285 0.000
S90-S99 Injuries to the ankle and foot
0.715 0.285 0.000
I95.1 Orthostatic hypotension
0.715 0.285 0.000
I62 Other nontraumatic intracranial haemorrhage
0.714 0.286 0.000
J98.8 Other specified respiratory disorders
0.714 0.286 0.000
M47.89 Other spondylosis (Site unspecified)
0.714 0.286 0.000
W10 Fall on and from stairs and steps
0.714 0.286 0.000
S01.7 Multiple open wounds of head
0.714 0.286 0.000
M75 Shoulder lesions
0.714 0.286 0.000
Q50-Q56 Congenital malformations of genital organs
0.713 0.287 0.000
R21 Rash and other nonspecific skin eruption
0.712 0.288 0.000
M84.0 Malunion of fracture
0.712 0.288 0.000
M49 Spondylopathies in diseases classified elsewhere
0.712 0.288 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.712 0.288 0.000
W15 Fall from cliff
0.712 0.288 0.000
W14 Fall from tree
0.712 0.288 0.000
W13 Fall from, out of or through building or structure
0.712 0.288 0.000
W12 Fall on and from scaffolding
0.712 0.288 0.000
W11 Fall on and from ladder
0.712 0.288 0.000
W09 Fall involving playground equipment
0.712 0.288 0.000
W05 Fall involving wheelchair
0.712 0.288 0.000
W04 Fall while being carried or supported by other persons
0.712 0.288 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.712 0.288 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.712 0.288 0.000
W00 Fall on same level involving ice and snow
0.712 0.288 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.711 0.289 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.711 0.289 0.000
M80 Osteoporosis with pathological fracture
0.710 0.290 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.710 0.290 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.710 0.290 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.710 0.290 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.710 0.290 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.710 0.290 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.710 0.290 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.710 0.290 0.000
T36 Poisoning by systemic antibiotics
0.710 0.290 0.000
R49 Voice disturbances
0.708 0.292 0.000
S62.60 Fracture of other finger (closed)
0.708 0.292 0.000
Y59 Other and unspecified vaccines and biological substances
0.708 0.292 0.000
Y58 Bacterial vaccines
0.708 0.292 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.708 0.292 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.708 0.292 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.708 0.292 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.708 0.292 0.000
Y48 Anaesthetics and therapeutic gases
0.708 0.292 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.708 0.292 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.708 0.292 0.000
M79.79 Fibromyalgia (Site unspecified)
0.706 0.293 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.706 0.294 0.000
J41 Simple and mucopurulent chronic bronchitis
0.705 0.295 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.704 0.295 0.000
M79.70 Fibromyalgia (Multiple sites)
0.704 0.296 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.704 0.296 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.703 0.297 0.000
Y98 Lifestyle-related condition
0.703 0.297 0.000
Y97 Environmental-pollution-related condition
0.703 0.297 0.000
Y96 Work-related condition
0.703 0.297 0.000
M82 Osteoporosis in diseases classified elsewhere
0.701 0.299 0.000
M54.9 Dorsalgia, unspecified
0.701 0.299 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.699 0.300 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.699 0.300 0.000
K13 Other diseases of lip and oral mucosa
0.699 0.301 0.000
M24 Other specific joint derangements
0.699 0.301 0.000
S65 Injury of blood vessels at wrist and hand level
0.698 0.302 0.000
W19.8 Other specified place
0.698 0.302 0.000
W19.5 Trade and service area
0.698 0.302 0.000
W19.0 Home
0.698 0.302 0.000
W19.7 Farm
0.698 0.302 0.000
W19.6 Industrial and construction area
0.698 0.302 0.000
W19.3 Sports and athletics area
0.698 0.302 0.000
W19.1 Residential institution
0.698 0.302 0.000
M50.9 Cervical disk disorder, unspecified
0.698 0.302 0.000
M50.8 Other cervical disk disorders
0.698 0.302 0.000
I45.3 Trifascicular block
0.698 0.302 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.697 0.302 0.000
Q80-Q89 Other congenital malformations
0.697 0.302 0.000
Q35-Q37 Cleft lip and cleft palate
0.697 0.302 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.697 0.302 0.000
M05-M14 Inflammatory polyarthropathies
0.697 0.303 0.000
S63.6 Sprain and strain of finger(s)
0.697 0.303 0.000
I46 Cardiac arrest
0.697 0.303 0.000
S01.1 Open wound of eyelid and periocular area
0.696 0.304 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.696 0.304 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.695 0.305 0.000
S09.7 Multiple injuries of head
0.695 0.305 0.000
S09.2 Traumatic rupture of ear drum
0.695 0.305 0.000
S09.1 Injury of muscle and tendon of head
0.695 0.305 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.695 0.305 0.000
T66-T78 Other and unspecified effects of external causes
0.694 0.306 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.694 0.306 0.000
I67.1 Cerebral aneurysm, nonruptured
0.694 0.306 0.000
F10.1 Harmful use
0.693 0.307 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.693 0.307 0.000
S06.4 Epidural haemorrhage
0.693 0.307 0.000
T79-T79 Certain early complications of trauma
0.693 0.307 0.000
M79.62 Pain in limb (Upper arm)
0.693 0.307 0.000
S06.9 Intracranial injury, unspecified
0.693 0.307 0.000
S06.5 Traumatic subdural haemorrhage
0.693 0.307 0.000
I60 Subarachnoid haemorrhage
0.693 0.307 0.000
K11 Diseases of salivary glands
0.692 0.308 0.000
Y42.7 Androgens and anabolic congeners
0.692 0.308 0.000
M54.4 Lumbago with sciatica
0.691 0.309 0.000
Y44 Agents primarily affecting blood constituents
0.689 0.310 0.000
R00.2 Palpitations
0.689 0.311 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.689 0.311 0.000
M75.1 Rotator cuff syndrome
0.689 0.311 0.000
M76 Enthesopathies of lower limb, excluding foot
0.688 0.311 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.688 0.311 0.000
I30 Acute pericarditis
0.688 0.312 0.000
J95.8 Other postprocedural respiratory disorders
0.687 0.313 0.000
S02 Fracture of skull and facial bones
0.687 0.313 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.686 0.314 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.686 0.314 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.685 0.314 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.685 0.315 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.685 0.315 0.000
I67.5 Moyamoya disease
0.685 0.315 0.000
I67.4 Hypertensive encephalopathy
0.685 0.315 0.000
I67.3 Progressive vascular leukoencephalopathy
0.685 0.315 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.685 0.315 0.000
K50-K52 Noninfective enteritis and colitis
0.685 0.315 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.684 0.315 0.000
T40.2 Other opioids
0.684 0.316 0.000
W06 Fall involving bed
0.684 0.316 0.000
W07.0 Home
0.684 0.316 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.683 0.317 0.000
M31 Other necrotising vasculopathies
0.683 0.317 0.000
M47.1 Other spondylosis with myelopathy
0.682 0.318 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.682 0.318 0.000
M71 Other bursopathies
0.681 0.318 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.681 0.319 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.681 0.319 0.000
M47.2 Other spondylosis with radiculopathy
0.680 0.320 0.000
J90 Pleural effusion, not elsewhere classified
0.680 0.320 0.000
I51.6 Cardiovascular disease, unspecified
0.680 0.320 0.000
I51.5 Myocardial degeneration
0.680 0.320 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.680 0.320 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.680 0.320 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.680 0.320 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.679 0.320 0.000
S62.4 Multiple fractures of metacarpal bones
0.679 0.321 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.679 0.321 0.000
F70-F79 Mental retardation
0.679 0.321 0.000
M79.8 Other specified soft tissue disorders
0.679 0.321 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.679 0.321 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.678 0.322 0.000
Q28 Other congenital malformations of circulatory system
0.677 0.322 0.000
I45.9 Conduction disorder, unspecified
0.677 0.323 0.000
J43.9 Emphysema, unspecified
0.677 0.323 0.000
T65 Toxic effect of other and unspecified substances
0.677 0.323 0.000
T63 Toxic effect of contact with venomous animals
0.677 0.323 0.000
T62 Toxic effect of other noxious substances eaten as food
0.677 0.323 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.677 0.323 0.000
T60 Toxic effect of pesticides
0.677 0.323 0.000
T59 Toxic effect of other gases, fumes and vapours
0.677 0.323 0.000
T57 Toxic effect of other inorganic substances
0.677 0.323 0.000
T56 Toxic effect of metals
0.677 0.323 0.000
T54 Toxic effect of corrosive substances
0.677 0.323 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.677 0.323 0.000
T52 Toxic effect of organic solvents
0.677 0.323 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.677 0.323 0.000
T58 Toxic effect of carbon monoxide
0.677 0.323 0.000
T55 Toxic effect of soaps and detergents
0.677 0.323 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.675 0.325 0.000
Y57.9 Drug or medicament, unspecified
0.674 0.326 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.674 0.326 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.674 0.326 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.673 0.327 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.673 0.327 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.673 0.327 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.673 0.327 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.673 0.327 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.673 0.327 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.673 0.327 0.000
F11 Mental and behavioural disorders due to use of opioids
0.673 0.327 0.000
S06.8 Other intracranial injuries
0.673 0.327 0.000
I86 Varicose veins of other sites
0.671 0.328 0.000
F10.9 Unspecified mental and behavioural disorder
0.671 0.329 0.000
F10.8 Other mental and behavioural disorders
0.671 0.329 0.000
F10.7 Residual and late-onset psychotic disorder
0.671 0.329 0.000
F10.6 Amnesic syndrome
0.671 0.329 0.000
F10.5 Psychotic disorder
0.671 0.329 0.000
F10.4 Withdrawal state with delirium
0.671 0.329 0.000
S69 Other and unspecified injuries of wrist and hand
0.670 0.330 0.000
Q66 Congenital deformities of feet
0.669 0.331 0.000
W29 Contact with other powered hand tools and household machinery
0.669 0.331 0.000
T43.9 Psychotropic drug, unspecified
0.668 0.332 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.668 0.332 0.000
T43.6 Psychostimulants with abuse potential
0.668 0.332 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.668 0.332 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.668 0.332 0.000
M53 Other dorsopathies, not elsewhere classified
0.668 0.332 0.000
Q23.1 Congenital insufficiency of aortic valve
0.667 0.332 0.000
I99 Other and unspecified disorders of circulatory system
0.667 0.333 0.000
M79.9 Soft tissue disorder, unspecified
0.667 0.333 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.667 0.333 0.000
M79.3 Panniculitis, unspecified
0.667 0.333 0.000
M79.2 Neuralgia and neuritis, unspecified
0.667 0.333 0.000
M79.1 Myalgia
0.667 0.333 0.000
J09-J18 Influenza and pneumonia
0.666 0.334 0.000
S61.0 Open wound of finger(s) without damage to nail
0.666 0.334 0.000
M85 Other disorders of bone density and structure
0.664 0.336 0.000
I85.9 Oesophageal varices without bleeding
0.664 0.336 0.000
M79.69 Pain in limb (Site unspecified)
0.663 0.337 0.000
I44.3 Other and unspecified atrioventricular block
0.663 0.337 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.661 0.338 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.661 0.338 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.661 0.338 0.000
T42.3 Barbiturates
0.661 0.338 0.000
T42.2 Succinimides and oxazolidinediones
0.661 0.338 0.000
T42.1 Iminostilbenes
0.661 0.338 0.000
T42.0 Hydantoin derivatives
0.661 0.338 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.661 0.339 0.000
T40.4 Other synthetic narcotics
0.661 0.339 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.661 0.339 0.000
I44.6 Other and unspecified fascicular block
0.660 0.340 0.000
I44.5 Left posterior fascicular block
0.660 0.340 0.000
I44.4 Left anterior fascicular block
0.660 0.340 0.000
R45.8 Other symptoms and signs involving emotional state
0.660 0.340 0.000
I37.1 Pulmonary valve insufficiency
0.660 0.340 0.000
T92 Sequelae of injuries of upper limb
0.660 0.340 0.000
S50-S59 Injuries to the elbow and forearm
0.659 0.340 0.000
I97.1 Other functional disturbances following cardiac surgery
0.659 0.341 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.659 0.341 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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