TreeWAS – Variant ID: rs117303215

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter I Certain infectious and parasitic diseases	0.998	0.002
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.996	0.004
T81 Complications of procedures, not elsewhere classified	0.996	0.004
A30-A49 Other bacterial diseases	0.996	0.004
Chapter XV Pregnancy, childbirth and the puerperium	0.996	0.004
A41 Other septicaemia	0.995	0.005
Chapter VIII Diseases of the ear and mastoid process	0.995	0.005
T36-T50 Poisoning by drugs, medicaments and biological substances	0.995	0.005
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.995	0.005
Chapter VI Diseases of the nervous system	0.993	0.007
D70-D77 Other diseases of blood and blood-forming organs	0.990	0.010
A41.9 Septicaemia, unspecified	0.988	0.012
H65-H75 Diseases of middle ear and mastoid	0.988	0.012
D70 Agranulocytosis	0.981	0.019
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.977	0.023
T81.3 Disruption of operation wound, not elsewhere classified	0.976	0.024
Chapter V Mental and behavioural disorders	0.973	0.027
T81.4 Infection following a procedure, not elsewhere classified	0.973	0.027
A41.5 Septicaemia due to other Gram-negative organisms	0.970	0.030
Chapter II Neoplasms	0.969	0.031
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.967	0.033
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.965	0.035
G90-G99 Other disorders of the nervous system	0.961	0.039
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.944	0.056
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.943	0.057
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.933	0.067
G30-G32 Other degenerative diseases of the nervous system	0.929	0.071
C77.0 Lymph nodes of head, face and neck	0.927	0.073
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.925	0.075
O94-O99 Other obstetric conditions, not elsewhere classified	0.922	0.078
O00-O08 Pregnancy with abortive outcome	0.919	0.081
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.915	0.085
O34 Maternal care for known or suspected abnormality of pelvic organs	0.914	0.086
H71 Cholesteatoma of middle ear	0.906	0.094
C77.3 Axillary and upper limb lymph nodes	0.901	0.099
H72 Perforation of tympanic membrane	0.897	0.103
H73 Other disorders of tympanic membrane	0.894	0.106
C77.2 Intra-abdominal lymph nodes	0.894	0.106
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.893	0.107
C50-C50 Malignant neoplasm of breast	0.892	0.108
H74 Other disorders of middle ear and mastoid	0.890	0.110
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.888	0.112
T51 Toxic effect of alcohol	0.882	0.117
O34.2 Maternal care due to uterine scar from previous surgery	0.878	0.122
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.873	0.127
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.869	0.131
O42 Premature rupture of membranes	0.865	0.135
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.862	0.138
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.862	0.138
S50-S59 Injuries to the elbow and forearm	0.860	0.140
G99 Other disorders of nervous system in diseases classified elsewhere	0.858	0.142
F30-F39 Mood [affective] disorders	0.857	0.143
F00-F09 Organic, including symptomatic, mental disorders	0.856	0.144
F20 Schizophrenia	0.851	0.149
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.846	0.154
D75 Other diseases of blood and blood-forming organs	0.843	0.157
H60-H62 Diseases of external ear	0.838	0.162
T51.0 Ethanol	0.838	0.162
C50 Malignant neoplasm of breast	0.837	0.163
H90-H95 Other disorders of ear	0.836	0.164
T81.7 Vascular complications following a procedure, not elsewhere classified	0.836	0.164
C50.4 Upper-outer quadrant of breast	0.834	0.166
O35 Maternal care for known or suspected foetal abnormality and damage	0.830	0.170
F29 Unspecified nonorganic psychosis	0.827	0.173
G30 Alzheimer's disease	0.823	0.177
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.821	0.179
T85 Complications of other internal prosthetic devices, implants and grafts	0.818	0.182
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.816	0.184
O47 False labour	0.816	0.184
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.815	0.185
H72.9 Perforation of tympanic membrane, unspecified	0.813	0.187
T15-T19 Effects of foreign body entering through natural orifice	0.807	0.193
T81.9 Unspecified complication of procedure	0.805	0.195
C80 Malignant neoplasm without specification of site	0.804	0.196
O48 Prolonged pregnancy	0.801	0.199
S10-S19 Injuries to the neck	0.799	0.201
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.799	0.201
O04 Medical abortion	0.797	0.203
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.795	0.205
T79-T79 Certain early complications of trauma	0.795	0.205
D80-D89 Certain disorders involving the immune mechanism	0.794	0.206
B02 Zoster [herpes zoster]	0.793	0.207
G50-G59 Nerve, nerve root and plexus disorders	0.791	0.209
S60-S69 Injuries to the wrist and hand	0.791	0.209
D37-D48 Neoplasms of uncertain or unknown behaviour	0.788	0.212
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.787	0.213
A65-A69 Other spirochaetal diseases	0.784	0.216
A41.1 Septicaemia due to other specified staphylococcus	0.781	0.218
Q50-Q56 Congenital malformations of genital organs	0.781	0.219
T46 Poisoning by agents primarily affecting the cardiovascular system	0.781	0.219
A49 Bacterial infection of unspecified site	0.780	0.220
H74.0 Tympanosclerosis	0.777	0.223
G95 Other diseases of spinal cord	0.777	0.223
T86 Failure and rejection of transplanted organs and tissues	0.775	0.225
C77.8 Lymph nodes of multiple regions	0.774	0.226
Q60-Q64 Congenital malformations of the urinary system	0.774	0.226
C79 Secondary malignant neoplasm of other sites	0.773	0.227
G93 Other disorders of brain	0.772	0.228
G96 Other disorders of central nervous system	0.771	0.229
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.771	0.229
H73.8 Other specified disorders of tympanic membrane	0.770	0.230
O42.9 Premature rupture of membranes, unspecified	0.770	0.230
G90 Disorders of autonomic nervous system	0.769	0.231
O03 Spontaneous abortion	0.768	0.232
G00-G09 Inflammatory diseases of the central nervous system	0.767	0.233
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.762	0.238
S00-S09 Injuries to the head	0.761	0.239
G99.2 Myelopathy in diseases classified elsewhere	0.760	0.240
T80 Complications following infusion, transfusion and therapeutic injection	0.760	0.240
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.759	0.241
T20-T25 Burns and corrosions of external body surface, specified by site	0.759	0.241
T56 Toxic effect of metals	0.757	0.243
C34 Malignant neoplasm of bronchus and lung	0.757	0.243
H73.9 Disorder of tympanic membrane, unspecified	0.757	0.243
F20.0 Paranoid schizophrenia	0.756	0.244
D69 Purpura and other haemorrhagic conditions	0.755	0.245
D55-D59 Haemolytic anaemias	0.755	0.245
B65-B83 Helminthiases	0.754	0.246
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.754	0.246
S80-S89 Injuries to the knee and lower leg	0.753	0.247
F31 Bipolar affective disorder	0.749	0.251
H72.2 Other marginal perforations of tympanic membrane	0.748	0.252
T40.4 Other synthetic narcotics	0.748	0.252
G40-G47 Episodic and paroxysmal disorders	0.747	0.253
T43.4 Butyrophenone and thioxanthene neuroleptics	0.746	0.254
H61 Other disorders of external ear	0.746	0.254
S40-S49 Injuries to the shoulder and upper arm	0.746	0.254
S51 Open wound of forearm	0.745	0.255
Q20-Q28 Congenital malformations of the circulatory system	0.745	0.255
C77.1 Intrathoracic lymph nodes	0.745	0.255
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.744	0.256
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.743	0.257
F80-F89 Disorders of psychological development	0.742	0.258
G20-G26 Extrapyramidal and movement disorders	0.741	0.259
D72 Other disorders of white blood cells	0.739	0.261
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.738	0.262
F33 Recurrent depressive disorder	0.738	0.262
T43.2 Other and unspecified antidepressants	0.737	0.263
A50-A64 Infections with a predominantly sexual mode of transmission	0.737	0.263
B95-B98 Bacterial, viral and other infectious agents	0.737	0.263
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.736	0.264
H74.3 Other acquired abnormalities of ear ossicles	0.735	0.265
S70-S79 Injuries to the hip and thigh	0.733	0.267
C49 Malignant neoplasm of other connective and soft tissue	0.732	0.267
O44 Placenta praevia	0.732	0.268
S01 Open wound of head	0.732	0.268
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.731	0.268
G30.9 Alzheimer's disease, unspecified	0.731	0.269
D75.8 Other specified diseases of blood and blood-forming organs	0.730	0.270
G70-G73 Diseases of myoneural junction and muscle	0.729	0.271
F00 Dementia in Alzheimer's disease	0.728	0.272
B35-B49 Mycoses	0.728	0.272
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.728	0.272
T87 Complications peculiar to reattachment and amputation	0.727	0.273
H92 Otalgia and effusion of ear	0.727	0.273
O02 Other abnormal products of conception	0.724	0.276
T43.5 Other and unspecified antipsychotics and neuroleptics	0.723	0.277
H90 Conductive and sensorineural hearing loss	0.722	0.278
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.718	0.282
F20.9 Schizophrenia, unspecified	0.717	0.283
B99-B99 Other infectious diseases	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Q80-Q89 Other congenital malformations	0.717	0.283
O85-O92 Complications predominantly related to the puerperium	0.716	0.284
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.716	0.284
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.716	0.284
F60-F69 Disorders of adult personality and behaviour	0.716	0.284
B85-B89 Pediculosis, acariasis and other infestations	0.715	0.285
B50-B64 Protozoal diseases	0.715	0.285
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.715	0.285
A75-A79 Rickettsioses	0.715	0.285
A70-A74 Other diseases caused by chlamydiae	0.715	0.285
A20-A28 Certain zoonotic bacterial diseases	0.715	0.285
A15-A19 Tuberculosis	0.715	0.285
A40 Streptococcal septicaemia	0.714	0.286
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.714	0.286
A48 Other bacterial diseases, not elsewhere classified	0.714	0.286
A44 Bartonellosis	0.714	0.286
A43 Nocardiosis	0.714	0.286
A42 Actinomycosis	0.714	0.286
A39 Meningococcal infection	0.714	0.286
A37 Whooping cough	0.714	0.286
A36 Diphtheria	0.714	0.286
A32 Listeriosis	0.714	0.286
A31 Infection due to other mycobacteria	0.714	0.286
A30 Leprosy [Hansen's disease]	0.714	0.286
A38 Scarlet fever	0.714	0.286
A35 Other tetanus	0.714	0.286
A34 Obstetrical tetanus	0.714	0.286
A33 Tetanus neonatorum	0.714	0.286
A41.4 Septicaemia due to anaerobes	0.714	0.286
A41.3 Septicaemia due to Haemophilus influenzae	0.714	0.286
A41.2 Septicaemia due to unspecified staphylococcus	0.714	0.286
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.713	0.287
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.713	0.287
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.713	0.287
T41 Poisoning by anaesthetics and therapeutic gases	0.713	0.287
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.713	0.287
T36 Poisoning by systemic antibiotics	0.713	0.287
C77.9 Lymph node, unspecified	0.713	0.287
D66 Hereditary factor VIII deficiency	0.711	0.289
C79.7 Secondary malignant neoplasm of adrenal gland	0.710	0.290
D74 Methaemoglobinaemia	0.710	0.290
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.710	0.290
D71 Functional disorders of polymorphonuclear neutrophils	0.710	0.290
T43.0 Tricyclic and tetracyclic antidepressants	0.709	0.291
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.709	0.291
H70 Mastoiditis and related conditions	0.709	0.291
H68 Eustachian salpingitis and obstruction	0.709	0.291
H67 Otitis media in diseases classified elsewhere	0.709	0.291
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.708	0.291
T39.1 4-Aminophenol derivatives	0.708	0.292
O46 Antepartum haemorrhage, not elsewhere classified	0.708	0.292
D68 Other coagulation defects	0.708	0.292
D73 Diseases of spleen	0.708	0.292
T42.4 Benzodiazepines	0.707	0.293
B90-B94 Sequelae of infectious and parasitic diseases	0.706	0.294
T18 Foreign body in alimentary tract	0.705	0.295
T81.8 Other complications of procedures, not elsewhere classified	0.705	0.295
B15-B19 Viral hepatitis	0.705	0.295
F99-F99 Unspecified mental disorder	0.701	0.299
T43.3 Phenothiazine antipsychotics and neuroleptics	0.701	0.299
O45 Premature separation of placenta [abruptio placentae]	0.700	0.300
O33 Maternal care for known or suspected disproportion	0.700	0.300
O31 Complications specific to multiple gestation	0.700	0.300
B00 Herpesviral [herpes simplex] infections	0.699	0.300
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.698	0.302
F70-F79 Mental retardation	0.698	0.302
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.697	0.303
A80-A89 Viral infections of the central nervous system	0.696	0.304
G93.3 Postviral fatigue syndrome	0.695	0.305
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.695	0.305
C40-C41 Malignant neoplasms of bone and articular cartilage	0.695	0.305
C76 Malignant neoplasm of other and ill-defined sites	0.693	0.307
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.693	0.307
O47.1 False labour at or after 37 completed weeks of gestation	0.692	0.308
G94 Other disorders of brain in diseases classified elsewhere	0.689	0.311
G98 Other disorders of nervous system, not elsewhere classified	0.689	0.311
G92 Toxic encephalopathy	0.689	0.311
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.689	0.311
F03 Unspecified dementia	0.688	0.312
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.688	0.312
Q00-Q07 Congenital malformations of the nervous system	0.686	0.314
T63 Toxic effect of contact with venomous animals	0.686	0.314
S66 Injury of muscle and tendon at wrist and hand level	0.685	0.315
G80-G83 Cerebral palsy and other paralytic syndromes	0.685	0.315
H65 Nonsuppurative otitis media	0.685	0.315
C32 Malignant neoplasm of larynx	0.682	0.317
Chapter XXII Codes for special purposes	0.680	0.320
O20-O29 Other maternal disorders predominantly related to pregnancy	0.680	0.320
B02.9 Zoster without complication	0.679	0.321
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.677	0.323
B20-B24 Human immunodeficiency virus [HIV] disease	0.676	0.323
T65 Toxic effect of other and unspecified substances	0.676	0.324
T62 Toxic effect of other noxious substances eaten as food	0.676	0.324
T61 Toxic effect of noxious substances eaten as seafood	0.676	0.324
T60 Toxic effect of pesticides	0.676	0.324
T59 Toxic effect of other gases, fumes and vapours	0.676	0.324
T57 Toxic effect of other inorganic substances	0.676	0.324
T54 Toxic effect of corrosive substances	0.676	0.324
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.676	0.324
T52 Toxic effect of organic solvents	0.676	0.324
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.676	0.324
T58 Toxic effect of carbon monoxide	0.676	0.324
T55 Toxic effect of soaps and detergents	0.676	0.324
H69 Other disorders of Eustachian tube	0.676	0.324
O32 Maternal care for known or suspected malpresentation of foetus	0.676	0.324
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.676	0.324
O04.4 Incomplete, without complication	0.675	0.325
G47 Sleep disorders	0.675	0.325
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.675	0.325
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.674	0.325
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.674	0.326
S20-S29 Injuries to the thorax	0.672	0.327
Q61 Cystic kidney disease	0.671	0.329
C34.1 Upper lobe, bronchus or lung	0.670	0.330
G35-G37 Demyelinating diseases of the central nervous system	0.670	0.330
Q51 Congenital malformations of uterus and cervix	0.669	0.330
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.669	0.331
Q35-Q37 Cleft lip and cleft palate	0.669	0.331
Q30-Q34 Congenital malformations of the respiratory system	0.669	0.331
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.669	0.331
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.666	0.334
B02.2 Zoster with other nervous system involvement	0.665	0.335
D75.9 Disease of blood and blood-forming organs, unspecified	0.664	0.336
F23 Acute and transient psychotic disorders	0.663	0.337
F28 Other nonorganic psychotic disorders	0.663	0.337
F24 Induced delusional disorder	0.663	0.337
F21 Schizotypal disorder	0.663	0.337
S61 Open wound of wrist and hand	0.663	0.337
G31.8 Other specified degenerative diseases of nervous system	0.662	0.338
S50 Superficial injury of forearm	0.662	0.338
F25 Schizoaffective disorders	0.661	0.338
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.661	0.339
O97 Death from sequelae of direct obstetric causes	0.661	0.339
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.661	0.339
O95 Obstetric death of unspecified cause	0.661	0.339
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.661	0.339
G57 Mononeuropathies of lower limb	0.660	0.340
T40.2 Other opioids	0.660	0.340
Q38-Q45 Other congenital malformations of the digestive system	0.659	0.341
O08 Complications following abortion and ectopic and molar pregnancy	0.659	0.341
O07 Failed attempted abortion	0.659	0.341
O06 Unspecified abortion	0.659	0.341
O05 Other abortion	0.659	0.341
O01 Hydatidiform mole	0.659	0.341
G95.9 Disease of spinal cord, unspecified	0.659	0.341
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.659	0.341
H74.8 Other specified disorders of middle ear and mastoid	0.658	0.341
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.658	0.342
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.658	0.342
G31.0 Circumscribed brain atrophy	0.658	0.342
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.657	0.343
F30 Manic episode	0.656	0.343
T43.9 Psychotropic drug, unspecified	0.656	0.344
T43.8 Other psychotropic drugs, not elsewhere classified	0.656	0.344
T43.6 Psychostimulants with abuse potential	0.656	0.344
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.656	0.344
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.656	0.344
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.655	0.345
O34.8 Maternal care for other abnormalities of pelvic organs	0.655	0.345
O34.7 Maternal care for abnormality of vulva and perineum	0.655	0.345
O34.6 Maternal care for abnormality of vagina	0.655	0.345
O34.5 Maternal care for other abnormalities of gravid uterus	0.655	0.345
O34.4 Maternal care for other abnormalities of cervix	0.655	0.345
O34.3 Maternal care for cervical incompetence	0.655	0.345
O34.0 Maternal care for congenital malformation of uterus	0.655	0.345
C64-C68 Malignant neoplasms of urinary tract	0.655	0.345
O41 Other disorders of amniotic fluid and membranes	0.654	0.345
C34.3 Lower lobe, bronchus or lung	0.655	0.345
F02 Dementia in other diseases classified elsewhere	0.654	0.345
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.653	0.346
O00 Ectopic pregnancy	0.653	0.347
O47.0 False labour before 37 completed weeks of gestation	0.653	0.347
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.652	0.347
O03.4 Incomplete, without complication	0.651	0.349
C77.4 Inguinal and lower limb lymph nodes	0.651	0.349
S42 Fracture of shoulder and upper arm	0.649	0.351
A41.0 Septicaemia due to Staphylococcus aureus	0.648	0.352
T79 Certain early complications of trauma, not elsewhere classified	0.648	0.352
O40 Polyhydramnios	0.647	0.353
D69.3 Idiopathic thrombocytopenic purpura	0.647	0.353
C80.0 Malignant neoplasm, primary site unknown, so stated	0.647	0.353
A41.8 Other specified septicaemia	0.646	0.354
Chapter IX Diseases of the circulatory system	0.646	0.354
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.645	0.354
T85.4 Mechanical complication of breast prosthesis and implant	0.645	0.355
S01.1 Open wound of eyelid and periocular area	0.644	0.356
H72.8 Other perforations of tympanic membrane	0.643	0.357
H72.1 Attic perforation of tympanic membrane	0.643	0.357
H73.1 Chronic myringitis	0.641	0.359
H73.0 Acute myringitis	0.641	0.359
T51.9 Alcohol, unspecified	0.641	0.359
F31.9 Bipolar affective disorder, unspecified	0.641	0.359
D67 Hereditary factor IX deficiency	0.640	0.360
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.640	0.360
S51.0 Open wound of elbow	0.640	0.360
H61.3 Acquired stenosis of external ear canal	0.639	0.361
O80-O84 Delivery	0.639	0.361
H74.9 Disorder of middle ear and mastoid, unspecified	0.638	0.362
H74.2 Discontinuity and dislocation of ear ossicles	0.638	0.362
H74.1 Adhesive middle ear disease	0.638	0.362
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.637	0.362
O30 Multiple gestation	0.637	0.362
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.637	0.363
B06 Rubella [German measles]	0.637	0.363
B05 Measles	0.637	0.363
B01 Varicella [chickenpox]	0.637	0.363
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.637	0.363
B04 Monkeypox	0.637	0.363
B03 Smallpox	0.637	0.363
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.636	0.364
G96.0 Cerebrospinal fluid leak	0.636	0.364
C80.9 Malignant neoplasm, unspecified	0.635	0.364
O04.9 Complete or unspecified, without complication	0.635	0.365
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.635	0.365
C49.1 Connective and soft tissue of upper limb, including shoulder	0.635	0.365
S12 Fracture of neck	0.634	0.365
M50-M54 Other dorsopathies	0.634	0.366
T51.8 Other alcohols	0.633	0.367
T51.3 Fusel oil	0.633	0.367
T51.2 2-Propanol	0.633	0.367
T51.1 Methanol	0.633	0.367
T18.1 Foreign body in oesophagus	0.633	0.367
G47.3 Sleep apnoea	0.632	0.368
A69 Other spirochaetal infections	0.631	0.369
G53 Cranial nerve disorders in diseases classified elsewhere	0.629	0.371
Q21 Congenital malformations of cardiac septa	0.629	0.371
D68.2 Hereditary deficiency of other clotting factors	0.629	0.371
C09 Malignant neoplasm of tonsil	0.629	0.371
G30.0 Alzheimer's disease with early onset	0.628	0.372
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.628	0.372
G24 Dystonia	0.627	0.373
O36 Maternal care for other known or suspected foetal problems	0.627	0.373
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.627	0.373
H66 Suppurative and unspecified otitis media	0.626	0.373
O02.1 Missed abortion	0.626	0.374
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.626	0.374
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.626	0.374
T42.5 Mixed antiepileptics, not elsewhere classified	0.626	0.374
T42.3 Barbiturates	0.626	0.374
T42.2 Succinimides and oxazolidinediones	0.626	0.374
T42.1 Iminostilbenes	0.626	0.374
T42.0 Hydantoin derivatives	0.626	0.374
H90.3 Sensorineural hearing loss, bilateral	0.626	0.374
T39.0 Salicylates	0.625	0.375
T56.8 Other metals	0.624	0.376
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.623	0.377
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.623	0.377
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.623	0.377
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.623	0.377
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.623	0.377
G31.9 Degenerative disease of nervous system, unspecified	0.623	0.377
A49.8 Other bacterial infections of unspecified site	0.622	0.377
S90-S99 Injuries to the ankle and foot	0.622	0.378
C50.3 Lower-inner quadrant of breast	0.622	0.378
G01 Meningitis in bacterial diseases classified elsewhere	0.621	0.379
S61.1 Open wound of finger(s) with damage to nail	0.621	0.379
O42.2 Premature rupture of membranes, labour delayed by therapy	0.620	0.379
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.620	0.380
S42.0 Fracture of clavicle	0.620	0.380
I30-I52 Other forms of heart disease	0.619	0.381
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.618	0.382
T40.8 Lysergide [LSD]	0.618	0.382
T40.7 Cannabis (derivatives)	0.618	0.382
T40.6 Other and unspecified narcotics	0.618	0.382
T40.5 Cocaine	0.618	0.382
T40.3 Methadone	0.618	0.382
T40.1 Heroin	0.618	0.382
T40.0 Opium	0.618	0.382
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.618	0.382
C38 Malignant neoplasm of heart, mediastinum and pleura	0.618	0.382
C31 Malignant neoplasm of accessory sinuses	0.618	0.382
C30 Malignant neoplasm of nasal cavity and middle ear	0.618	0.382
C37 Malignant neoplasm of thymus	0.618	0.382
C33 Malignant neoplasm of trachea	0.618	0.382
S59 Other and unspecified injuries of forearm	0.616	0.384
S58 Traumatic amputation of forearm	0.616	0.384
S57 Crushing injury of forearm	0.616	0.384
S56 Injury of muscle and tendon at forearm level	0.616	0.384
S55 Injury of blood vessels at forearm level	0.616	0.384
S54 Injury of nerves at forearm level	0.616	0.384
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.616	0.384
I34 Nonrheumatic mitral valve disorders	0.616	0.384
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.615	0.385
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.615	0.385
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.615	0.385
F38 Other mood [affective] disorders	0.614	0.386
F34 Persistent mood [affective] disorders	0.614	0.386
F39 Unspecified mood [affective] disorder	0.614	0.386
G93.1 Anoxic brain damage, not elsewhere classified	0.614	0.386
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.613	0.386
F09 Unspecified organic or symptomatic mental disorder	0.613	0.386
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.613	0.386
D50-D53 Nutritional anaemias	0.613	0.386
H61.8 Other specified disorders of external ear	0.613	0.386
H74.4 Polyp of middle ear	0.613	0.387
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.612	0.388
F01 Vascular dementia	0.611	0.389
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.611	0.389
B07 Viral warts	0.610	0.390
F20.8 Other schizophrenia	0.610	0.390
F20.6 Simple schizophrenia	0.610	0.390
F20.5 Residual schizophrenia	0.610	0.390
F20.4 Postschizophrenic depression	0.610	0.390
F20.3 Undifferentiated schizophrenia	0.610	0.390
F20.2 Catatonic schizophrenia	0.610	0.390
F20.1 Hebephrenic schizophrenia	0.610	0.390
S51.9 Open wound of forearm, part unspecified	0.610	0.390
H92.1 Otorrhoea	0.610	0.390
T50.9 Other and unspecified drugs, medicaments and biological substances	0.610	0.390
F05 Delirium, not induced by alcohol and other psychoactive substances	0.610	0.390
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.609	0.390
D84 Other immunodeficiencies	0.609	0.391
F31.6 Bipolar affective disorder, current episode mixed	0.609	0.391
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.609	0.391
C49.0 Connective and soft tissue of head, face and neck	0.609	0.391
G54 Nerve root and plexus disorders	0.609	0.391
D41.4 Bladder	0.608	0.392
D75.2 Essential thrombocytosis	0.607	0.392
M45-M49 Spondylopathies	0.607	0.393
G44 Other headache syndromes	0.607	0.393
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.607	0.393
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.606	0.394
O15 Eclampsia	0.606	0.394
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.606	0.394
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.606	0.394
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.606	0.394
S14 Injury of nerves and spinal cord at neck level	0.606	0.394
G31.2 Degeneration of nervous system due to alcohol	0.605	0.394
G91 Hydrocephalus	0.605	0.395
D75.0 Familial erythrocytosis	0.605	0.395
I34.1 Mitral (valve) prolapse	0.605	0.395
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.604	0.396
G97.0 Cerebrospinal fluid leak from spinal puncture	0.604	0.396

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations