TreeWAS – Variant ID: rs11735066

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.998	0.002
S20-S29 Injuries to the thorax	0.991	0.009
Chapter V Mental and behavioural disorders	0.985	0.015
Chapter XXII Codes for special purposes	0.984	0.016
Chapter VIII Diseases of the ear and mastoid process	0.981	0.019
T36-T50 Poisoning by drugs, medicaments and biological substances	0.981	0.019
Chapter IV Endocrine, nutritional and metabolic diseases	0.980	0.020
E10 Insulin-dependent diabetes mellitus	0.979	0.021
E10-E14 Diabetes mellitus	0.978	0.022
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.976	0.024
T15-T19 Effects of foreign body entering through natural orifice	0.969	0.031
S60-S69 Injuries to the wrist and hand	0.965	0.035
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.955	0.045
Chapter VII Diseases of the eye and adnexa	0.953	0.047
S22 Fracture of rib(s), sternum and thoracic spine	0.953	0.047
H65-H75 Diseases of middle ear and mastoid	0.952	0.048
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.951	0.049
Q00-Q07 Congenital malformations of the nervous system	0.949	0.051
Q60-Q64 Congenital malformations of the urinary system	0.948	0.052
E10.9 Without complications	0.947	0.053
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.947	0.053
S68 Traumatic amputation of wrist and hand	0.945	0.055
F17 Mental and behavioural disorders due to use of tobacco	0.944	0.056
T18 Foreign body in alimentary tract	0.943	0.057
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.942	0.058
F17.1 Harmful use	0.942	0.058
S20 Superficial injury of thorax	0.937	0.063
H18 Other disorders of cornea	0.935	0.065
S32 Fracture of lumbar spine and pelvis	0.933	0.067
E10.3 With ophthalmic complications	0.931	0.069
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.930	0.070
T42.4 Benzodiazepines	0.923	0.077
Chapter XX External causes of morbidity and mortality	0.923	0.077
T18.1 Foreign body in oesophagus	0.914	0.086
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.905	0.095
Q05 Spina bifida	0.905	0.095
F40-F48 Neurotic, stress-related and somatoform disorders	0.901	0.099
S20.2 Contusion of thorax	0.884	0.116
Q61 Cystic kidney disease	0.884	0.116
E10.1 With ketoacidosis	0.878	0.122
F60-F69 Disorders of adult personality and behaviour	0.876	0.124
E10.4 With neurological complications	0.875	0.125
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.874	0.126
Q05.9 Spina bifida, unspecified	0.874	0.126
T20-T25 Burns and corrosions of external body surface, specified by site	0.873	0.126
F43 Reaction to severe stress, and adjustment disorders	0.873	0.127
S70-S79 Injuries to the hip and thigh	0.870	0.130
S22.4 Multiple fractures of ribs	0.869	0.131
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.867	0.133
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.867	0.133
S22.3 Fracture of rib	0.861	0.139
H72 Perforation of tympanic membrane	0.861	0.139
H18.5 Hereditary corneal dystrophies	0.860	0.140
U80 Agent resistant to penicillin and related antibiotics	0.859	0.141
H46-H48 Disorders of optic nerve and visual pathways	0.858	0.142
H66 Suppurative and unspecified otitis media	0.852	0.148
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.851	0.149
U51 Admission status on psychiatric patients	0.848	0.152
H18.4 Corneal degeneration	0.838	0.162
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.825	0.175
E70-E90 Metabolic disorders	0.825	0.175
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.823	0.177
U89 Agent resistant to other and unspecified antibiotics	0.820	0.180
Q50-Q56 Congenital malformations of genital organs	0.820	0.180
Q61.3 Polycystic kidney, unspecified	0.819	0.181
T46 Poisoning by agents primarily affecting the cardiovascular system	0.814	0.186
S32.3 Fracture of ilium	0.810	0.190
S22.40 Multiple fractures of ribs (closed)	0.810	0.190
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.809	0.191
F43.1 Posttraumatic stress disorder	0.803	0.197
T84.0 Mechanical complication of internal joint prosthesis	0.802	0.198
H60-H62 Diseases of external ear	0.802	0.198
X60-X84 Intentional self-harm	0.802	0.198
F60 Specific personality disorders	0.801	0.199
H74 Other disorders of middle ear and mastoid	0.798	0.202
S32.0 Fracture of lumbar vertebra	0.798	0.202
S22.30 Fracture of rib (closed)	0.795	0.204
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.792	0.208
S64 Injury of nerves at wrist and hand level	0.792	0.208
F43.0 Acute stress reaction	0.792	0.208
F00-F09 Organic, including symptomatic, mental disorders	0.790	0.210
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.790	0.210
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.789	0.211
Q63 Other congenital malformations of kidney	0.789	0.211
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.787	0.213
S36 Injury of intra-abdominal organs	0.786	0.214
E14 Unspecified diabetes mellitus	0.784	0.216
H18.9 Disorder of cornea, unspecified	0.782	0.217
S63.6 Sprain and strain of finger(s)	0.782	0.218
H65 Nonsuppurative otitis media	0.779	0.221
Q20-Q28 Congenital malformations of the circulatory system	0.777	0.223
S32.7 Multiple fractures of lumbar spine and pelvis	0.776	0.224
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.773	0.227
S21 Open wound of thorax	0.769	0.230
E78.0 Pure hypercholesterolaemia	0.767	0.233
U51.1 Previously admitted to a psychiatric hospital of the provider	0.766	0.234
E83 Disorders of mineral metabolism	0.762	0.238
S10-S19 Injuries to the neck	0.762	0.238
S65 Injury of blood vessels at wrist and hand level	0.761	0.239
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.760	0.240
H20 Iridocyclitis	0.758	0.242
H66.3 Other chronic suppurative otitis media	0.756	0.244
S31 Open wound of abdomen, lower back and pelvis	0.756	0.244
H16 Keratitis	0.752	0.248
S30 Superficial injury of abdomen, lower back and pelvis	0.752	0.248
H72.0 Central perforation of tympanic membrane	0.751	0.249
H80-H83 Diseases of inner ear	0.751	0.249
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.749	0.251
F48 Other neurotic disorders	0.749	0.251
H18.2 Other corneal oedema	0.749	0.251
E10.2 With renal complications	0.748	0.251
H90-H95 Other disorders of ear	0.748	0.252
S79 Other and unspecified injuries of hip and thigh	0.746	0.254
Chapter VI Diseases of the nervous system	0.746	0.254
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.746	0.254
H46 Optic neuritis	0.745	0.255
S22.0 Fracture of thoracic vertebra	0.744	0.256
X40-X49 Accidental poisoning by and exposure to noxious substances	0.741	0.259
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.741	0.259
T85 Complications of other internal prosthetic devices, implants and grafts	0.741	0.259
S20.8 Superficial injuries of other and unspecified parts of thorax	0.740	0.260
S27 Injury of other and unspecified intrathoracic organs	0.740	0.260
Q80-Q89 Other congenital malformations	0.739	0.261
T00-T07 Injuries involving multiple body regions	0.738	0.262
U88 Agent resistant to multiple antibiotics	0.737	0.263
S32.5 Fracture of pubis	0.736	0.264
Q07 Other congenital malformations of nervous system	0.735	0.265
T18.5 Foreign body in anus and rectum	0.734	0.265
T21 Burn and corrosion of trunk	0.734	0.266
T40.4 Other synthetic narcotics	0.734	0.266
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.733	0.267
T16 Foreign body in ear	0.732	0.268
H69 Other disorders of Eustachian tube	0.731	0.269
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.731	0.269
Q66 Congenital deformities of feet	0.730	0.270
E14.3 With ophthalmic complications	0.730	0.270
H72.9 Perforation of tympanic membrane, unspecified	0.730	0.270
F70-F79 Mental retardation	0.730	0.270
Y60-Y69 Misadventures to patients during surgical and medical care	0.727	0.273
F11 Mental and behavioural disorders due to use of opioids	0.723	0.276
S32.30 Fracture of ilium (closed)	0.722	0.278
U89.8 Agent resistant to other single specified antibiotic	0.722	0.278
H17 Corneal scars and opacities	0.721	0.279
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.720	0.280
E10.8 With unspecified complications	0.718	0.281
H15 Disorders of sclera	0.718	0.282
W50-W64 Exposure to animate mechanical forces	0.718	0.282
T18.9 Foreign body in alimentary tract, part unspecified	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E83.4 Disorders of magnesium metabolism	0.716	0.284
H18.6 Keratoconus	0.716	0.284
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.715	0.285
Q35-Q37 Cleft lip and cleft palate	0.715	0.285
Q30-Q34 Congenital malformations of the respiratory system	0.715	0.285
U80.1 Methicillin resistant agent	0.715	0.285
E13 Other specified diabetes mellitus	0.713	0.286
E16 Other disorders of pancreatic internal secretion	0.713	0.286
H47 Other disorders of optic [2nd] nerve and visual pathways	0.713	0.287
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.712	0.288
U80.0 Penicillin resistant agent	0.712	0.288
X20-X29 Contact with venomous animals and plants	0.711	0.289
S63.5 Sprain and strain of wrist	0.711	0.289
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.711	0.289
S26 Injury of heart	0.711	0.289
S25 Injury of blood vessels of thorax	0.711	0.289
S24 Injury of nerves and spinal cord at thorax level	0.711	0.289
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.711	0.289
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.707	0.293
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.707	0.293
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.706	0.293
X50-X57 Overexertion, travel and privation	0.705	0.295
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.704	0.296
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.703	0.297
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.703	0.297
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.703	0.297
T41 Poisoning by anaesthetics and therapeutic gases	0.703	0.297
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.703	0.297
T36 Poisoning by systemic antibiotics	0.703	0.297
T17 Foreign body in respiratory tract	0.703	0.297
H61 Other disorders of external ear	0.702	0.298
E10.7 With multiple complications	0.702	0.298
E10.6 With other specified complications	0.702	0.298
E10.0 With coma	0.702	0.298
T80 Complications following infusion, transfusion and therapeutic injection	0.701	0.299
E12 Malnutrition-related diabetes mellitus	0.701	0.299
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.701	0.299
W20-W49 Exposure to inanimate mechanical forces	0.701	0.299
S32.00 Fracture of lumbar vertebra (closed)	0.701	0.299
Q64 Other congenital malformations of urinary system	0.700	0.300
E40-E46 Malnutrition	0.700	0.300
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.700	0.300
S37 Injury of urinary and pelvic organs	0.700	0.300
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.700	0.300
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.700	0.300
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.700	0.300
H91 Other hearing loss	0.699	0.301
S66 Injury of muscle and tendon at wrist and hand level	0.698	0.302
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.698	0.302
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.696	0.303
Q38-Q45 Other congenital malformations of the digestive system	0.696	0.304
T19 Foreign body in genito-urinary tract	0.695	0.305
T15 Foreign body on external eye	0.695	0.305
H25-H28 Disorders of lens	0.695	0.305
E10.5 With peripheral circulatory complications	0.694	0.306
U80.8 Agent resistant to other penicillin-related antibiotic	0.693	0.307
E83.3 Disorders of phosphorus metabolism	0.693	0.307
Q76 Congenital malformations of spine and bony thorax	0.692	0.307
G00-G09 Inflammatory diseases of the central nervous system	0.691	0.309
H21 Other disorders of iris and ciliary body	0.690	0.310
V98-V99 Other and unspecified transport accidents	0.689	0.311
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.688	0.312
F43.2 Adjustment disorders	0.688	0.312
H18.8 Other specified disorders of cornea	0.687	0.313
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.685	0.315
T42.5 Mixed antiepileptics, not elsewhere classified	0.685	0.315
T42.3 Barbiturates	0.685	0.315
T42.2 Succinimides and oxazolidinediones	0.685	0.315
T42.1 Iminostilbenes	0.685	0.315
T42.0 Hydantoin derivatives	0.685	0.315
Q61.0 Congenital single renal cyst	0.685	0.315
S70 Superficial injury of hip and thigh	0.685	0.315
S68.0 Traumatic amputation of thumb (complete)(partial)	0.684	0.316
S22.9 Fracture of bony thorax, part unspecified	0.683	0.317
S22.8 Fracture of other parts of bony thorax	0.683	0.317
T66-T78 Other and unspecified effects of external causes	0.683	0.317
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.683	0.317
H68 Eustachian salpingitis and obstruction	0.683	0.317
H67 Otitis media in diseases classified elsewhere	0.683	0.317
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.683	0.317
S80-S89 Injuries to the knee and lower leg	0.683	0.317
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.682	0.318
F18 Mental and behavioural disorders due to use of volatile solvents	0.682	0.318
F16 Mental and behavioural disorders due to use of hallucinogens	0.682	0.318
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.682	0.318
F14 Mental and behavioural disorders due to use of cocaine	0.682	0.318
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.682	0.318
Q60 Renal agenesis and other reduction defects of kidney	0.681	0.319
S22.2 Fracture of sternum	0.681	0.319
Q06 Other congenital malformations of spinal cord	0.680	0.320
Q04 Other congenital malformations of brain	0.680	0.320
Q03 Congenital hydrocephalus	0.680	0.320
Q01 Encephalocele	0.680	0.320
Q00 Anencephaly and similar malformations	0.680	0.320
Q02 Microcephaly	0.680	0.320
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.680	0.320
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.680	0.320
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.680	0.320
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.679	0.321
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.679	0.321
T88 Other complications of surgical and medical care, not elsewhere classified	0.679	0.321
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.677	0.323
S68.8 Traumatic amputation of other parts of wrist and hand	0.677	0.323
S68.4 Traumatic amputation of hand at wrist level	0.677	0.323
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.677	0.323
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.677	0.323
F17.9 Unspecified mental and behavioural disorder	0.677	0.323
F17.8 Other mental and behavioural disorders	0.677	0.323
F17.7 Residual and late-onset psychotic disorder	0.677	0.323
F17.6 Amnesic syndrome	0.677	0.323
F17.5 Psychotic disorder	0.677	0.323
F17.4 Withdrawal state with delirium	0.677	0.323
F17.3 Withdrawal state	0.677	0.323
F17.0 Acute intoxication	0.677	0.323
T18.8 Foreign body in other and multiple parts of alimentary tract	0.676	0.324
T18.4 Foreign body in colon	0.676	0.324
T18.3 Foreign body in small intestine	0.676	0.324
T18.2 Foreign body in stomach	0.676	0.324
T18.0 Foreign body in mouth	0.676	0.324
U81 Agent resistant to vancomycin and related antibiotics	0.676	0.324
U50 Level of care administered to neonates	0.676	0.324
U07 Emergency use of U07	0.676	0.324
U06 Emergency use of U06	0.676	0.324
U04 Severe acute respiratory syndrome [SARS]	0.676	0.324
U52 First in a series of a regular day/night admissions	0.676	0.324
U89.9 Agent resistant to unspecified antibiotic	0.675	0.325
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.675	0.325
X10-X19 Contact with heat and hot substances	0.674	0.325
F60.5 Anankastic personality disorder	0.674	0.326
H53-H54 Visual disturbances and blindness	0.672	0.328
H74.3 Other acquired abnormalities of ear ossicles	0.672	0.328
S69 Other and unspecified injuries of wrist and hand	0.672	0.328
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.672	0.328
S20.7 Multiple superficial injuries of thorax	0.672	0.328
S20.4 Other superficial injuries of back wall of thorax	0.672	0.328
S20.3 Other superficial injuries of front wall of thorax	0.672	0.328
S20.1 Other and unspecified superficial injuries of breast	0.672	0.328
S20.0 Contusion of breast	0.672	0.328
H00 Hordeolum and chalazion	0.671	0.329
H18.7 Other corneal deformities	0.671	0.329
H18.3 Changes in corneal membranes	0.671	0.329
H18.1 Bullous keratopathy	0.671	0.329
H18.0 Corneal pigmentations and deposits	0.671	0.329
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.669	0.331
S67 Crushing injury of wrist and hand	0.669	0.331
S32.2 Fracture of coccyx	0.669	0.331
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.669	0.331
T79-T79 Certain early complications of trauma	0.669	0.331
S29 Other and unspecified injuries of thorax	0.668	0.332
F99-F99 Unspecified mental disorder	0.668	0.332
F60.9 Personality disorder, unspecified	0.667	0.333
E73 Lactose intolerance	0.667	0.333
T46.4 Angiotensin-converting-enzyme inhibitors	0.666	0.334
Y43 Primarily systemic agents	0.665	0.335
T85.4 Mechanical complication of breast prosthesis and implant	0.664	0.336
V40-V49 Car occupant injured in transport accident	0.664	0.336
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.663	0.337
Y35-Y36 Legal intervention and operations of war	0.661	0.338
Y10-Y34 Event of undetermined intent	0.661	0.338
Y00-Y09 Assault	0.661	0.338
X85-X99 Assault	0.661	0.338
X30-X39 Exposure to forces of nature	0.661	0.338
X00-X09 Exposure to smoke, fire and flames	0.661	0.338
W75-W84 Other accidental threats to breathing	0.661	0.338
W65-W74 Accidental drowning and submersion	0.661	0.338
V95-V97 Air and space transport accidents	0.661	0.338
V90-V94 Water transport accidents	0.661	0.338
V70-V79 Bus occupant injured in transport accident	0.661	0.338
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.661	0.338
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.661	0.338
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.661	0.338
V01-V09 Pedestrian injured in transport accident	0.661	0.338
G90-G99 Other disorders of the nervous system	0.661	0.339
H65.3 Chronic mucoid otitis media	0.660	0.340
Q61.2 Polycystic kidney, adult type	0.659	0.341
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.658	0.342
S79.9 Unspecified injury of hip and thigh	0.657	0.343
H91.9 Hearing loss, unspecified	0.656	0.344
H80 Otosclerosis	0.655	0.345
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.655	0.345
S32.4 Fracture of acetabulum	0.653	0.347
Q12 Congenital lens malformations	0.653	0.347
H00.1 Chalazion	0.653	0.347
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.653	0.347
H61.2 Impacted cerumen	0.652	0.348
S22.1 Multiple fractures of thoracic spine	0.652	0.348
Q53 Undescended testicle	0.652	0.348
U51.0 Not Previously admitted to a psyciatric hospital	0.651	0.349
S22.5 Flail chest	0.651	0.349
T91 Sequelae of injuries of neck and trunk	0.651	0.349
U84 Resistance to other antimicrobial drugs	0.649	0.351
U83 Resistance to other antibiotics	0.649	0.351
U82 Resistance to betalactam antibiotics	0.649	0.351
U85 Resistance to antineoplastic drugs	0.649	0.351
H70 Mastoiditis and related conditions	0.649	0.351
Q05.8 Sacral spina bifida without hydrocephalus	0.649	0.351
Q05.7 Lumbar spina bifida without hydrocephalus	0.649	0.351
Q05.6 Thoracic spina bifida without hydrocephalus	0.649	0.351
Q05.5 Cervical spina bifida without hydrocephalus	0.649	0.351
Q05.4 Unspecified spina bifida with hydrocephalus	0.649	0.351
Q05.3 Sacral spina bifida with hydrocephalus	0.649	0.351
Q05.2 Lumbar spina bifida with hydrocephalus	0.649	0.351
Q05.1 Thoracic spina bifida with hydrocephalus	0.649	0.351
Q05.0 Cervical spina bifida with hydrocephalus	0.649	0.351
Q27 Other congenital malformations of peripheral vascular system	0.649	0.351
X58-X59 Accidental exposure to other and unspecified factors	0.647	0.352
F44 Dissociative [conversion] disorders	0.646	0.354
H66.4 Suppurative otitis media, unspecified	0.645	0.355
E78.1 Pure hyperglyceridaemia	0.645	0.355
F42 Obsessive-compulsive disorder	0.643	0.357
H74.4 Polyp of middle ear	0.643	0.357
H66.9 Otitis media, unspecified	0.643	0.357
S32.1 Fracture of sacrum	0.643	0.357
Y57 Other and unspecified drugs and medicaments	0.642	0.358
S64.2 Injury of radial nerve at wrist and hand level	0.642	0.358
F48.0 Neurasthenia	0.640	0.360
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.637	0.363
S64.0 Injury of ulnar nerve at wrist and hand level	0.637	0.363
F02 Dementia in other diseases classified elsewhere	0.636	0.364
F80-F89 Disorders of psychological development	0.635	0.365
S63.3 Traumatic rupture of ligament of wrist and carpus	0.635	0.365
X63.0 Home	0.634	0.365
H16.0 Corneal ulcer	0.634	0.366
Q61.9 Cystic kidney disease, unspecified	0.634	0.366
Q61.8 Other cystic kidney diseases	0.634	0.366
Q61.5 Medullary cystic kidney	0.634	0.366
Q61.4 Renal dysplasia	0.634	0.366
Q61.1 Polycystic kidney, infantile type	0.634	0.366
F60.6 Anxious [avoidant] personality disorder	0.633	0.367
Q66.8 Other congenital deformities of feet	0.632	0.368
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.632	0.368
Q63.0 Accessory kidney	0.631	0.369
F05 Delirium, not induced by alcohol and other psychoactive substances	0.630	0.370
F68 Other disorders of adult personality and behaviour	0.628	0.372
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.628	0.372
F65 Disorders of sexual preference	0.628	0.372
F63 Habit and impulse disorders	0.628	0.372
F62 Enduring personality changes, not attributable to brain damage and disease	0.628	0.372
F69 Unspecified disorder of adult personality and behaviour	0.628	0.372
F61 Mixed and other personality disorders	0.628	0.372
S63.1 Dislocation finger	0.627	0.373
S63.7 Sprain and strain of other and unspecified parts of hand	0.627	0.373
S63.2 Multiple dislocations of fingers	0.627	0.373
S63.0 Dislocation of wrist	0.627	0.373
S90-S99 Injuries to the ankle and foot	0.627	0.373
T25 Burn and corrosion of ankle and foot	0.626	0.374
T20 Burn and corrosion of head and neck	0.626	0.374
Q63.1 Lobulated, fused and horseshoe kidney	0.626	0.374
T45.5 Anticoagulants	0.626	0.374
F43.8 Other reactions to severe stress	0.626	0.374
S36.8 Injury of other intra-abdominal organs	0.625	0.375
Q51 Congenital malformations of uterus and cervix	0.625	0.375
F00 Dementia in Alzheimer's disease	0.624	0.375
S78 Traumatic amputation of hip and thigh	0.624	0.376
S77 Crushing injury of hip and thigh	0.624	0.376
S76 Injury of muscle and tendon at hip and thigh level	0.624	0.376
S75 Injury of blood vessels at hip and thigh level	0.624	0.376
S74 Injury of nerves at hip and thigh level	0.624	0.376
G93 Other disorders of brain	0.624	0.376
F01 Vascular dementia	0.623	0.377
S22.41 Multiple fractures of ribs (open)	0.623	0.377
S30.1 Contusion of abdominal wall	0.623	0.377
H72.2 Other marginal perforations of tympanic membrane	0.623	0.377
V20-V29 Motorcycle rider injured in transport accident	0.622	0.378
T21.2 Burn of second degree of trunk	0.622	0.378
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.622	0.378
Q78 Other osteochondrodysplasias	0.621	0.378
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.621	0.378
Q75 Other congenital malformations of skull and face bones	0.621	0.378
Q74 Other congenital malformations of limb(s)	0.621	0.378
Q73 Reduction defects of unspecified limb	0.621	0.378
Q72 Reduction defects of lower limb	0.621	0.378
Q71 Reduction defects of upper limb	0.621	0.378
Q70 Syndactyly	0.621	0.378
Q69 Polydactyly	0.621	0.378
Q68 Other congenital musculoskeletal deformities	0.621	0.378
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.621	0.378
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.621	0.379
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.621	0.379
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.621	0.379
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.621	0.379
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.621	0.379
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.621	0.379
T44.1 Other parasympathomimetics [cholinergics]	0.621	0.379
T44.0 Anticholinesterase agents	0.621	0.379
F64 Gender identity disorders	0.619	0.381
Y95 Nosocomial condition	0.618	0.382
S22.31 Fracture of rib (open)	0.617	0.382
H72.1 Attic perforation of tympanic membrane	0.617	0.383
T87 Complications peculiar to reattachment and amputation	0.617	0.383
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.615	0.385
T45.1 Antineoplastic and immunosuppressive drugs	0.615	0.385
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.615	0.385
E78.8 Other disorders of lipoprotein metabolism	0.614	0.386
H25 Senile cataract	0.614	0.386
Q54 Hypospadias	0.612	0.388
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.612	0.388
H66.2 Chronic atticoantral suppurative otitis media	0.611	0.389
H66.1 Chronic tubotympanic suppurative otitis media	0.611	0.389
H66.0 Acute suppurative otitis media	0.611	0.389
S21.2 Open wound of back wall of thorax	0.610	0.390
S66.8 Injury of other muscles and tendons at wrist and hand level	0.610	0.390
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.610	0.390
G70-G73 Diseases of myoneural junction and muscle	0.609	0.391
U51.2 Previously admitted to a psychiatric hospital of another provider	0.608	0.392
E78.4 Other hyperlipidaemia	0.605	0.395
F12 Mental and behavioural disorders due to use of cannabinoids	0.603	0.397
H74.1 Adhesive middle ear disease	0.603	0.397
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.603	0.397
H20.1 Chronic iridocyclitis	0.603	0.397
S50-S59 Injuries to the elbow and forearm	0.603	0.397
V80-V89 Other land transport accidents	0.602	0.397
H20.9 Iridocyclitis, unspecified	0.601	0.398
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.600	0.400
Y48 Anaesthetics and therapeutic gases	0.600	0.400
H71 Cholesteatoma of middle ear	0.599	0.401
W00-W19 Falls	0.599	0.401
S36.0 Injury of spleen	0.598	0.402
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.598	0.402
E14.4 With neurological complications	0.598	0.402
G06 Intracranial and intraspinal abscess and granuloma	0.597	0.403
S72 Fracture of femur	0.596	0.404
S32.50 Fracture of pubis (closed)	0.596	0.404
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.596	0.404
S22.00 Fracture of thoracic vertebra (closed)	0.594	0.406
S64.1 Injury of median nerve at wrist and hand level	0.593	0.407
E88 Other metabolic disorders	0.592	0.408
E15 Nondiabetic hypoglycaemic coma	0.591	0.408
E84 Cystic fibrosis	0.591	0.409
E79 Disorders of purine and pyrimidine metabolism	0.591	0.409
E77 Disorders of glycoprotein metabolism	0.591	0.409
E76 Disorders of glycosaminoglycan metabolism	0.591	0.409
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.591	0.409
E72 Other disorders of amino-acid metabolism	0.591	0.409
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.591	0.409
E70 Disorders of aromatic amino-acid metabolism	0.591	0.409
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.591	0.409
X78 Intentional self-harm by sharp object	0.590	0.409
S71 Open wound of hip and thigh	0.590	0.410
S65.1 Injury of radial artery at wrist and hand level	0.590	0.410
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.590	0.410
T40.8 Lysergide [LSD]	0.590	0.410
T40.7 Cannabis (derivatives)	0.590	0.410
T40.6 Other and unspecified narcotics	0.590	0.410
T40.5 Cocaine	0.590	0.410
T40.3 Methadone	0.590	0.410
T40.1 Heroin	0.590	0.410

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations