TreeWAS – Variant ID: rs117362991

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter V Mental and behavioural disorders	0.998	0.002
Chapter VIII Diseases of the ear and mastoid process	0.997	0.003
Chapter I Certain infectious and parasitic diseases	0.996	0.004
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.995	0.005
I25 Chronic ischaemic heart disease	0.992	0.008
I21 Acute myocardial infarction	0.992	0.008
H90-H95 Other disorders of ear	0.991	0.009
Chapter IV Endocrine, nutritional and metabolic diseases	0.990	0.010
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.989	0.011
F17 Mental and behavioural disorders due to use of tobacco	0.986	0.014
I30-I52 Other forms of heart disease	0.983	0.017
Chapter XII Diseases of the skin and subcutaneous tissue	0.980	0.020
I34 Nonrheumatic mitral valve disorders	0.978	0.022
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.974	0.026
E10-E14 Diabetes mellitus	0.967	0.033
F17.1 Harmful use	0.965	0.035
I34.0 Mitral (valve) insufficiency	0.962	0.038
F17.2 Dependence syndrome	0.957	0.043
I25.1 Atherosclerotic heart disease	0.956	0.044
I25.9 Chronic ischaemic heart disease, unspecified	0.950	0.050
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.950	0.050
E70-E90 Metabolic disorders	0.949	0.051
L80-L99 Other disorders of the skin and subcutaneous tissue	0.945	0.055
E10 Insulin-dependent diabetes mellitus	0.942	0.058
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.942	0.058
I21.9 Acute myocardial infarction, unspecified	0.939	0.061
I20 Angina pectoris	0.929	0.071
D80-D89 Certain disorders involving the immune mechanism	0.924	0.076
T79-T79 Certain early complications of trauma	0.920	0.080
L50-L54 Urticaria and erythema	0.920	0.080
A00-A09 Intestinal infectious diseases	0.919	0.081
H65-H75 Diseases of middle ear and mastoid	0.918	0.082
H91 Other hearing loss	0.918	0.082
B35-B49 Mycoses	0.912	0.088
A30-A49 Other bacterial diseases	0.910	0.090
H90 Conductive and sensorineural hearing loss	0.910	0.090
H92 Otalgia and effusion of ear	0.908	0.092
Chapter XV Pregnancy, childbirth and the puerperium	0.906	0.094
B25-B34 Other viral diseases	0.905	0.095
D86 Sarcoidosis	0.904	0.096
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.898	0.102
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.894	0.106
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.888	0.112
I21.4 Acute subendocardial myocardial infarction	0.879	0.121
D86.9 Sarcoidosis, unspecified	0.879	0.121
I22 Subsequent myocardial infarction	0.878	0.121
S40-S49 Injuries to the shoulder and upper arm	0.878	0.122
T92 Sequelae of injuries of upper limb	0.877	0.123
I21.0 Acute transmural myocardial infarction of anterior wall	0.875	0.125
L97 Ulcer of lower limb, not elsewhere classified	0.873	0.127
O94-O99 Other obstetric conditions, not elsewhere classified	0.867	0.133
I34.1 Mitral (valve) prolapse	0.866	0.134
T79 Certain early complications of trauma, not elsewhere classified	0.866	0.134
H91.9 Hearing loss, unspecified	0.865	0.135
B37 Candidiasis	0.852	0.148
I20.0 Unstable angina	0.851	0.149
I31 Other diseases of pericardium	0.850	0.150
E10.1 With ketoacidosis	0.850	0.150
L90 Atrophic disorders of skin	0.848	0.152
E78.5 Hyperlipidaemia, unspecified	0.848	0.152
I21.2 Acute transmural myocardial infarction of other sites	0.847	0.153
E87 Other disorders of fluid, electrolyte and acid-base balance	0.845	0.155
S10-S19 Injuries to the neck	0.845	0.155
Chapter X Diseases of the respiratory system	0.845	0.155
A04 Other bacterial intestinal infections	0.844	0.156
T93 Sequelae of injuries of lower limb	0.841	0.159
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.839	0.161
H72 Perforation of tympanic membrane	0.838	0.162
B34 Viral infection of unspecified site	0.837	0.163
I25.2 Old myocardial infarction	0.836	0.164
I05-I09 Chronic rheumatic heart diseases	0.836	0.164
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.826	0.174
F20 Schizophrenia	0.825	0.175
L52 Erythema nodosum	0.824	0.176
E10.9 Without complications	0.821	0.179
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.820	0.180
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.819	0.181
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.815	0.185
A49 Bacterial infection of unspecified site	0.814	0.186
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.813	0.187
L20-L30 Dermatitis and eczema	0.813	0.187
T79.3 Post-traumatic wound infection, not elsewhere classified	0.810	0.190
T90 Sequelae of injuries of head	0.808	0.192
I51 Complications and ill-defined descriptions of heart disease	0.805	0.195
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.805	0.195
H92.1 Otorrhoea	0.803	0.197
F40-F48 Neurotic, stress-related and somatoform disorders	0.802	0.198
H90.3 Sensorineural hearing loss, bilateral	0.802	0.198
S30 Superficial injury of abdomen, lower back and pelvis	0.802	0.198
T91 Sequelae of injuries of neck and trunk	0.801	0.199
T92.2 Sequelae of fracture at wrist and hand level	0.798	0.202
F00-F09 Organic, including symptomatic, mental disorders	0.797	0.202
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.794	0.206
I49 Other cardiac arrhythmias	0.793	0.207
B65-B83 Helminthiases	0.792	0.208
L91 Hypertrophic disorders of skin	0.791	0.209
E10.3 With ophthalmic complications	0.791	0.209
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.783	0.217
H66 Suppurative and unspecified otitis media	0.783	0.217
L50 Urticaria	0.783	0.217
B15-B19 Viral hepatitis	0.781	0.219
I70-I79 Diseases of arteries, arterioles and capillaries	0.781	0.219
Q80-Q89 Other congenital malformations	0.780	0.220
H60-H62 Diseases of external ear	0.779	0.221
A46 Erysipelas	0.778	0.222
E74 Other disorders of carbohydrate metabolism	0.777	0.223
B34.9 Viral infection, unspecified	0.775	0.225
B37.0 Candidal stomatitis	0.773	0.227
F25 Schizoaffective disorders	0.769	0.231
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.767	0.233
I31.3 Pericardial effusion (noninflammatory)	0.767	0.233
D86.0 Sarcoidosis of lung	0.765	0.235
I20.1 Angina pectoris with documented spasm	0.765	0.235
S70-S79 Injuries to the hip and thigh	0.763	0.237
H92.0 Otalgia	0.760	0.240
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.757	0.243
E87.2 Acidosis	0.754	0.246
O20-O29 Other maternal disorders predominantly related to pregnancy	0.753	0.247
T15-T19 Effects of foreign body entering through natural orifice	0.751	0.249
B90-B94 Sequelae of infectious and parasitic diseases	0.750	0.250
F22 Persistent delusional disorders	0.749	0.251
E10.5 With peripheral circulatory complications	0.747	0.253
T94 Sequelae of injuries involving multiple and unspecified body regions	0.746	0.254
F29 Unspecified nonorganic psychosis	0.745	0.255
I37 Pulmonary valve disorders	0.745	0.255
L89 Decubitus ulcer	0.744	0.256
B37.8 Candidiasis of other sites	0.740	0.260
E14 Unspecified diabetes mellitus	0.740	0.260
F80-F89 Disorders of psychological development	0.739	0.261
A04.7 Enterocolitis due to Clostridium difficile	0.739	0.261
I22.9 Subsequent myocardial infarction of unspecified site	0.739	0.261
S00-S09 Injuries to the head	0.738	0.262
E11 Non-insulin-dependent diabetes mellitus	0.737	0.263
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.735	0.265
J95-J99 Other diseases of the respiratory system	0.734	0.266
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.733	0.267
E87.0 Hyperosmolality and hypernatraemia	0.732	0.268
H93 Other disorders of ear, not elsewhere classified	0.731	0.268
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.731	0.269
S41 Open wound of shoulder and upper arm	0.731	0.269
L90.5 Scar conditions and fibrosis of skin	0.730	0.270
H72.0 Central perforation of tympanic membrane	0.730	0.270
I33 Acute and subacute endocarditis	0.728	0.272
Chapter VI Diseases of the nervous system	0.726	0.274
E85 Amyloidosis	0.726	0.274
E87.5 Hyperkalaemia	0.725	0.275
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.724	0.276
I26 Pulmonary embolism	0.723	0.277
Chapter XXII Codes for special purposes	0.722	0.278
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.722	0.278
J00-J06 Acute upper respiratory infections	0.722	0.278
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.722	0.278
F20.0 Paranoid schizophrenia	0.720	0.280
D70-D77 Other diseases of blood and blood-forming organs	0.720	0.280
H90.2 Conductive hearing loss, unspecified	0.719	0.281
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
E65-E68 Obesity and other hyperalimentation	0.716	0.283
S43.0 Dislocation of shoulder joint	0.716	0.284
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.715	0.285
F70-F79 Mental retardation	0.715	0.285
L95 Vasculitis limited to skin, not elsewhere classified	0.715	0.285
E78.9 Disorder of lipoprotein metabolism, unspecified	0.715	0.285
B99-B99 Other infectious diseases	0.714	0.286
B85-B89 Pediculosis, acariasis and other infestations	0.714	0.286
B50-B64 Protozoal diseases	0.714	0.286
B20-B24 Human immunodeficiency virus [HIV] disease	0.714	0.286
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.714	0.286
A75-A79 Rickettsioses	0.714	0.286
A70-A74 Other diseases caused by chlamydiae	0.714	0.286
A65-A69 Other spirochaetal diseases	0.714	0.286
A20-A28 Certain zoonotic bacterial diseases	0.714	0.286
A15-A19 Tuberculosis	0.714	0.286
T33-T35 Frostbite	0.713	0.287
T26-T28 Burns and corrosions confined to eye and internal organs	0.713	0.287
T20-T25 Burns and corrosions of external body surface, specified by site	0.713	0.287
T00-T07 Injuries involving multiple body regions	0.713	0.287
I24 Other acute ischaemic heart diseases	0.713	0.287
A04.5 Campylobacter enteritis	0.713	0.287
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.713	0.287
I25.6 Silent myocardial ischaemia	0.711	0.288
I25.4 Coronary artery aneurysm	0.711	0.288
I25.3 Aneurysm of heart	0.711	0.288
I25.0 Atherosclerotic cardiovascular disease, so described	0.711	0.288
I21.X Presumed acute myicardial infaction (unconfirmed)	0.711	0.289
I21.3 Acute transmural myocardial infarction of unspecified site	0.711	0.289
H94 Other disorders of ear in diseases classified elsewhere	0.711	0.289
I22.0 Subsequent myocardial infarction of anterior wall	0.710	0.290
T51 Toxic effect of alcohol	0.710	0.290
E10.2 With renal complications	0.710	0.290
I10-I15 Hypertensive diseases	0.710	0.290
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.709	0.291
F18 Mental and behavioural disorders due to use of volatile solvents	0.709	0.291
F16 Mental and behavioural disorders due to use of hallucinogens	0.709	0.291
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.709	0.291
F14 Mental and behavioural disorders due to use of cocaine	0.709	0.291
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.709	0.291
F12 Mental and behavioural disorders due to use of cannabinoids	0.709	0.291
F11 Mental and behavioural disorders due to use of opioids	0.709	0.291
E13 Other specified diabetes mellitus	0.709	0.291
L90.0 Lichen sclerosus et atrophicus	0.708	0.292
F60-F69 Disorders of adult personality and behaviour	0.708	0.292
Q60-Q64 Congenital malformations of the urinary system	0.707	0.293
F17.9 Unspecified mental and behavioural disorder	0.707	0.293
F17.8 Other mental and behavioural disorders	0.707	0.293
F17.7 Residual and late-onset psychotic disorder	0.707	0.293
F17.6 Amnesic syndrome	0.707	0.293
F17.5 Psychotic disorder	0.707	0.293
F17.4 Withdrawal state with delirium	0.707	0.293
F17.3 Withdrawal state	0.707	0.293
F17.0 Acute intoxication	0.707	0.293
O80-O84 Delivery	0.707	0.293
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.706	0.294
A40 Streptococcal septicaemia	0.705	0.295
I52 Other heart disorders in diseases classified elsewhere	0.704	0.295
I48 Atrial fibrillation and flutter	0.704	0.295
I43 Cardiomyopathy in diseases classified elsewhere	0.704	0.295
I41 Myocarditis in diseases classified elsewhere	0.704	0.295
I40 Acute myocarditis	0.704	0.295
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.704	0.295
I36 Nonrheumatic tricuspid valve disorders	0.704	0.295
I32 Pericarditis in diseases classified elsewhere	0.704	0.295
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.705	0.295
L10-L14 Bullous disorders	0.703	0.297
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.702	0.298
I34.8 Other nonrheumatic mitral valve disorders	0.701	0.299
I34.2 Nonrheumatic mitral (valve) stenosis	0.701	0.299
H70 Mastoiditis and related conditions	0.701	0.299
E78.8 Other disorders of lipoprotein metabolism	0.700	0.299
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.700	0.300
L85 Other epidermal thickening	0.700	0.300
T98 Sequelae of other and unspecified effects of external causes	0.699	0.301
T95 Sequelae of burns, corrosions and frostbite	0.699	0.301
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.699	0.301
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.699	0.301
T79.8 Other early complications of trauma	0.699	0.301
I47 Paroxysmal tachycardia	0.698	0.302
I30 Acute pericarditis	0.696	0.304
Q38-Q45 Other congenital malformations of the digestive system	0.695	0.305
Chapter XX External causes of morbidity and mortality	0.694	0.306
L53 Other erythematous conditions	0.694	0.306
A50-A64 Infections with a predominantly sexual mode of transmission	0.694	0.306
E12 Malnutrition-related diabetes mellitus	0.693	0.306
O85-O92 Complications predominantly related to the puerperium	0.692	0.308
B44 Aspergillosis	0.692	0.308
A08 Viral and other specified intestinal infections	0.690	0.310
H74 Other disorders of middle ear and mastoid	0.689	0.310
E16 Other disorders of pancreatic internal secretion	0.689	0.311
T90.2 Sequelae of fracture of skull and facial bones	0.689	0.311
E80 Disorders of porphyrin and bilirubin metabolism	0.689	0.311
D80 Immunodeficiency with predominantly antibody defects	0.687	0.313
O20 Haemorrhage in early pregnancy	0.686	0.314
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.686	0.314
A80-A89 Viral infections of the central nervous system	0.683	0.316
H72.8 Other perforations of tympanic membrane	0.683	0.317
S80-S89 Injuries to the knee and lower leg	0.683	0.317
E40-E46 Malnutrition	0.682	0.318
T93.2 Sequelae of other fractures of lower limb	0.682	0.318
S50-S59 Injuries to the elbow and forearm	0.681	0.319
D55-D59 Haemolytic anaemias	0.681	0.319
I20.8 Other forms of angina pectoris	0.681	0.319
E84 Cystic fibrosis	0.680	0.320
E79 Disorders of purine and pyrimidine metabolism	0.680	0.320
E77 Disorders of glycoprotein metabolism	0.680	0.320
E76 Disorders of glycosaminoglycan metabolism	0.680	0.320
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.680	0.320
E73 Lactose intolerance	0.680	0.320
E72 Other disorders of amino-acid metabolism	0.680	0.320
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.680	0.320
E70 Disorders of aromatic amino-acid metabolism	0.680	0.320
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.680	0.320
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.679	0.321
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.679	0.321
A49.0 Staphylococcal infection, unspecified	0.678	0.322
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.677	0.323
L94 Other localised connective tissue disorders	0.677	0.323
L93 Lupus erythematosus	0.677	0.323
L87 Transepidermal elimination disorders	0.677	0.323
L88 Pyoderma gangrenosum	0.677	0.323
L86 Keratoderma in diseases classified elsewhere	0.677	0.323
L83 Acanthosis nigricans	0.677	0.323
L80 Vitiligo	0.677	0.323
M20-M25 Other joint disorders	0.677	0.323
T91.8 Sequelae of other specified injuries of neck and trunk	0.677	0.323
J80-J84 Other respiratory diseases principally affecting the interstitium	0.676	0.324
L50.9 Urticaria, unspecified	0.676	0.324
E10.8 With unspecified complications	0.675	0.324
E10.7 With multiple complications	0.675	0.324
E10.6 With other specified complications	0.675	0.324
E10.0 With coma	0.675	0.324
F23 Acute and transient psychotic disorders	0.675	0.325
F28 Other nonorganic psychotic disorders	0.675	0.325
F24 Induced delusional disorder	0.675	0.325
F21 Schizotypal disorder	0.675	0.325
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.675	0.325
S90-S99 Injuries to the ankle and foot	0.673	0.327
F03 Unspecified dementia	0.670	0.330
H66.9 Otitis media, unspecified	0.669	0.331
L98.8 Other specified disorders of skin and subcutaneous tissue	0.668	0.332
E20-E35 Disorders of other endocrine glands	0.667	0.333
L21 Seborrhoeic dermatitis	0.666	0.334
A49.8 Other bacterial infections of unspecified site	0.663	0.337
D84 Other immunodeficiencies	0.662	0.338
D83 Common variable immunodeficiency	0.662	0.338
D82 Immunodeficiency associated with other major defects	0.662	0.338
D81 Combined immunodeficiencies	0.662	0.338
L30 Other dermatitis	0.661	0.339
L54 Erythema in diseases classified elsewhere	0.659	0.341
L51 Erythema multiforme	0.659	0.341
B25 Cytomegaloviral disease	0.659	0.341
A07 Other protozoal intestinal diseases	0.659	0.341
A06 Amoebiasis	0.659	0.341
A05 Other bacterial foodborne intoxications	0.659	0.341
A03 Shigellosis	0.659	0.341
A02 Other Salmonella infections	0.659	0.341
A01 Typhoid and paratyphoid fevers	0.659	0.341
A00 Cholera	0.659	0.341
I49.0 Ventricular fibrillation and flutter	0.659	0.341
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.659	0.341
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.658	0.342
H68 Eustachian salpingitis and obstruction	0.658	0.342
H67 Otitis media in diseases classified elsewhere	0.658	0.342
I22.8 Subsequent myocardial infarction of other sites	0.658	0.342
H91.8 Other specified hearing loss	0.658	0.342
H91.3 Deaf mutism, not elsewhere classified	0.658	0.342
H91.2 Sudden idiopathic hearing loss	0.658	0.342
H91.1 Presbycusis	0.658	0.342
H91.0 Ototoxic hearing loss	0.658	0.342
M80-M85 Disorders of bone density and structure	0.657	0.342
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.657	0.343
M23 Internal derangement of knee	0.657	0.343
Chapter VII Diseases of the eye and adnexa	0.657	0.343
L84 Corns and callosities	0.656	0.344
S14 Injury of nerves and spinal cord at neck level	0.656	0.344
B37.9 Candidiasis, unspecified	0.656	0.344
L40-L45 Papulosquamous disorders	0.655	0.345
L91.0 Keloid scar	0.654	0.346
I05 Rheumatic mitral valve diseases	0.654	0.346
B48 Other mycoses, not elsewhere classified	0.654	0.346
B47 Mycetoma	0.654	0.346
B46 Zygomycosis	0.654	0.346
B45 Cryptococcosis	0.654	0.346
B43 Chromomycosis and phaeomycotic abscess	0.654	0.346
B42 Sporotrichosis	0.654	0.346
B41 Paracoccidioidomycosis	0.654	0.346
B40 Blastomycosis	0.654	0.346
B39 Histoplasmosis	0.654	0.346
B38 Coccidioidomycosis	0.654	0.346
B36 Other superficial mycoses	0.654	0.346
B49 Unspecified mycosis	0.654	0.346
I51.4 Myocarditis, unspecified	0.654	0.346
O60-O75 Complications of labour and delivery	0.653	0.347
E74.3 Other disorders of intestinal carbohydrate absorption	0.653	0.347
H95.1 Other disorders following mastoidectomy	0.653	0.347
I49.5 Sick sinus syndrome	0.653	0.347
A48 Other bacterial diseases, not elsewhere classified	0.652	0.347
A44 Bartonellosis	0.652	0.347
A43 Nocardiosis	0.652	0.347
A42 Actinomycosis	0.652	0.347
A39 Meningococcal infection	0.652	0.347
A37 Whooping cough	0.652	0.347
A36 Diphtheria	0.652	0.347
A32 Listeriosis	0.652	0.347
A31 Infection due to other mycobacteria	0.652	0.347
A30 Leprosy [Hansen's disease]	0.652	0.347
A38 Scarlet fever	0.652	0.347
A35 Other tetanus	0.652	0.347
A34 Obstetrical tetanus	0.652	0.347
A33 Tetanus neonatorum	0.652	0.347
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.652	0.348
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.652	0.348
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.652	0.348
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.652	0.348
H90.0 Conductive hearing loss, bilateral	0.652	0.348
E88 Other metabolic disorders	0.652	0.348
H92.2 Otorrhagia	0.651	0.349
B34.8 Other viral infections of unspecified site	0.650	0.350
B33 Other viral diseases, not elsewhere classified	0.649	0.351
B30 Viral conjunctivitis	0.649	0.351
B27 Infectious mononucleosis	0.649	0.351
B26 Mumps	0.649	0.351
H90.5 Sensorineural hearing loss, unspecified	0.649	0.351
D86.8 Sarcoidosis of other and combined sites	0.648	0.351
D86.3 Sarcoidosis of skin	0.648	0.351
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.648	0.351
D86.1 Sarcoidosis of lymph nodes	0.648	0.351
I51.9 Heart disease, unspecified	0.648	0.352
F05 Delirium, not induced by alcohol and other psychoactive substances	0.648	0.352
I60-I69 Cerebrovascular diseases	0.647	0.353
F41 Other anxiety disorders	0.647	0.353
I08 Multiple valve diseases	0.646	0.354
B80 Enterobiasis	0.646	0.354
F25.9 Schizoaffective disorder, unspecified	0.645	0.355
H72.9 Perforation of tympanic membrane, unspecified	0.645	0.355
I07 Rheumatic tricuspid valve diseases	0.644	0.356
E78.6 Lipoprotein deficiency	0.644	0.356
E78.4 Other hyperlipidaemia	0.644	0.356
E78.3 Hyperchylomicronaemia	0.644	0.356
E78.1 Pure hyperglyceridaemia	0.644	0.356
S01 Open wound of head	0.642	0.358
I20.9 Angina pectoris, unspecified	0.642	0.358
S12 Fracture of neck	0.642	0.358
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.642	0.358
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.641	0.359
Q35-Q37 Cleft lip and cleft palate	0.641	0.359
Q30-Q34 Congenital malformations of the respiratory system	0.641	0.359
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.641	0.359
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.641	0.359
Q85 Phakomatoses, not elsewhere classified	0.641	0.359
I38 Endocarditis, valve unspecified	0.641	0.359
I21.1 Acute transmural myocardial infarction of inferior wall	0.641	0.359
L60-L75 Disorders of skin appendages	0.640	0.360
J03 Acute tonsillitis	0.640	0.360
F99-F99 Unspecified mental disorder	0.639	0.361
F20.9 Schizophrenia, unspecified	0.639	0.361
I42 Cardiomyopathy	0.639	0.361
I49.8 Other specified cardiac arrhythmias	0.639	0.361
I72 Other aneurysm	0.637	0.363
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.637	0.363
S37 Injury of urinary and pelvic organs	0.637	0.363
S36 Injury of intra-abdominal organs	0.637	0.363
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.637	0.363
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.637	0.363
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.637	0.363
S31 Open wound of abdomen, lower back and pelvis	0.637	0.363
F40 Phobic anxiety disorders	0.637	0.363
Q89 Other congenital malformations, not elsewhere classified	0.636	0.364
I35 Nonrheumatic aortic valve disorders	0.636	0.364
Q20-Q28 Congenital malformations of the circulatory system	0.636	0.364
D72 Other disorders of white blood cells	0.635	0.365
J90-J94 Other diseases of pleura	0.635	0.365
I25.5 Ischaemic cardiomyopathy	0.634	0.366
H73 Other disorders of tympanic membrane	0.634	0.366
E78.2 Mixed hyperlipidaemia	0.632	0.368
H69 Other disorders of Eustachian tube	0.631	0.368
E14.3 With ophthalmic complications	0.631	0.369
A49.1 Streptococcal infection, unspecified	0.631	0.369
E50-E64 Other nutritional deficiencies	0.630	0.370
S48 Traumatic amputation of shoulder and upper arm	0.629	0.371
S46 Injury of muscle and tendon at shoulder and upper arm level	0.629	0.371
S45 Injury of blood vessels at shoulder and upper arm level	0.629	0.371
S44 Injury of nerves at shoulder and upper arm level	0.629	0.371
S47 Crushing injury of shoulder and upper arm	0.629	0.371
T92.9 Sequelae of unspecified injury of upper limb	0.629	0.371
T92.8 Sequelae of other specified injuries of upper limb	0.629	0.371
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.629	0.371
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.629	0.371
T92.4 Sequelae of injury of nerve of upper limb	0.629	0.371
T92.0 Sequelae of open wound of upper limb	0.629	0.371
J98 Other respiratory disorders	0.627	0.373
S41.1 Open wound of upper arm	0.626	0.374
M23.3 Other meniscus derangements	0.626	0.374
E10.4 With neurological complications	0.624	0.375
T51.0 Ethanol	0.624	0.376
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.623	0.377
L92 Granulomatous disorders of skin and subcutaneous tissue	0.623	0.377
J60-J70 Lung diseases due to external agents	0.622	0.378
I12 Hypertensive renal disease	0.622	0.378
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.621	0.379
O97 Death from sequelae of direct obstetric causes	0.621	0.379
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.621	0.379
O95 Obstetric death of unspecified cause	0.621	0.379
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.621	0.379
H30-H36 Disorders of choroid and retina	0.621	0.379
T79.9 Unspecified early complication of trauma	0.621	0.379
T79.7 Traumatic subcutaneous emphysema	0.621	0.379
T79.6 Traumatic ischaemia of muscle	0.621	0.379
T79.5 Traumatic anuria	0.621	0.379
T79.4 Traumatic shock	0.621	0.379
T79.2 Traumatic secondary and recurrent haemorrhage	0.621	0.379
T79.1 Fat embolism (traumatic)	0.621	0.379
T79.0 Air embolism (traumatic)	0.621	0.379
I22.1 Subsequent myocardial infarction of inferior wall	0.621	0.379
O20.0 Threatened abortion	0.620	0.380
H60 Otitis externa	0.620	0.380
S40 Superficial injury of shoulder and upper arm	0.617	0.383
A04.8 Other specified bacterial intestinal infections	0.617	0.383
E83 Disorders of mineral metabolism	0.617	0.383
I78 Diseases of capillaries	0.616	0.383
O63 Long labour	0.616	0.384
S19 Other and unspecified injuries of neck	0.615	0.385
H71 Cholesteatoma of middle ear	0.615	0.385
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.614	0.386
I45 Other conduction disorders	0.613	0.386
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.613	0.387
B16 Acute hepatitis B	0.612	0.388
M65-M68 Disorders of synovium and tendon	0.612	0.388
E89.2 Postprocedural hypoparathyroidism	0.611	0.388
L91.8 Other hypertrophic disorders of skin	0.611	0.389
F22.0 Delusional disorder	0.611	0.389
B37.7 Candidal septicaemia	0.611	0.389
B37.6 Candidal endocarditis	0.611	0.389
B37.5 Candidal meningitis	0.611	0.389
B37.4 Candidiasis of other urogenital sites	0.611	0.389
B37.2 Candidiasis of skin and nail	0.611	0.389
B37.1 Pulmonary candidiasis	0.611	0.389

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations