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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117458579
log Bayes Factor = 15.4218
Chromosome 12   position 15,351,989  (GRCh37) Explore rs117458579 on Ensembl!
Variant rs117458579 is part of Cluster X0126

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M15-M19 Arthrosis
1.000 0.000 0.000
M19 Other arthrosis
0.999 0.001 0.000
M19.9 Arthrosis, unspecified
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.997 0.003 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.995 0.005 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.993 0.007 0.000
M50-M54 Other dorsopathies
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
M54 Dorsalgia
0.988 0.012 0.000
M54.5 Low back pain
0.977 0.023 0.000
S60-S69 Injuries to the wrist and hand
0.975 0.025 0.000
I47 Paroxysmal tachycardia
0.975 0.025 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.972 0.028 0.000
M20-M25 Other joint disorders
0.971 0.029 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.964 0.036 0.000
M70-M79 Other soft tissue disorders
0.964 0.036 0.000
M45-M49 Spondylopathies
0.956 0.044 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.954 0.046 0.000
I60-I69 Cerebrovascular diseases
0.952 0.048 0.000
M80-M85 Disorders of bone density and structure
0.948 0.052 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.946 0.054 0.000
I47.1 Supraventricular tachycardia
0.946 0.054 0.000
M54.57 Low back pain (Lumbosacral region)
0.944 0.056 0.000
Chapter VIII Diseases of the ear and mastoid process
0.943 0.057 0.000
M75 Shoulder lesions
0.943 0.057 0.000
M17 Gonarthrosis [arthrosis of knee]
0.939 0.061 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.931 0.069 0.000
Chapter VI Diseases of the nervous system
0.927 0.073 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.927 0.073 0.000
S20-S29 Injuries to the thorax
0.926 0.074 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.926 0.074 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.921 0.079 0.000
M20 Acquired deformities of fingers and toes
0.916 0.084 0.000
M47 Spondylosis
0.910 0.090 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.907 0.093 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.904 0.096 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.904 0.096 0.000
Chapter V Mental and behavioural disorders
0.904 0.096 0.000
M23 Internal derangement of knee
0.896 0.104 0.000
M54.56 Low back pain (Lumbar region)
0.894 0.106 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.887 0.113 0.000
M81 Osteoporosis without pathological fracture
0.883 0.117 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.881 0.119 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.879 0.121 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.878 0.122 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.877 0.123 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.874 0.126 0.000
M19.98 Arthrosis, unspecified (Other)
0.874 0.126 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.872 0.128 0.000
Y95 Nosocomial condition
0.871 0.129 0.000
Chapter VII Diseases of the eye and adnexa
0.867 0.133 0.000
M17.1 Other primary gonarthrosis
0.867 0.133 0.000
S64 Injury of nerves at wrist and hand level
0.863 0.137 0.000
M20.1 Hallux valgus (acquired)
0.862 0.138 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.861 0.139 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.861 0.139 0.000
M75.1 Rotator cuff syndrome
0.860 0.140 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.860 0.140 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.859 0.141 0.000
I46 Cardiac arrest
0.858 0.142 0.000
T43.2 Other and unspecified antidepressants
0.858 0.142 0.000
M54.9 Dorsalgia, unspecified
0.855 0.145 0.000
I50 Heart failure
0.853 0.147 0.000
W20-W49 Exposure to inanimate mechanical forces
0.852 0.148 0.000
H65-H75 Diseases of middle ear and mastoid
0.850 0.150 0.000
I51 Complications and ill-defined descriptions of heart disease
0.849 0.151 0.000
I34 Nonrheumatic mitral valve disorders
0.844 0.156 0.000
I45 Other conduction disorders
0.842 0.158 0.000
I65.2 Occlusion and stenosis of carotid artery
0.841 0.159 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.840 0.160 0.000
H90-H95 Other disorders of ear
0.839 0.161 0.000
M81.9 Osteoporosis, unspecified
0.837 0.163 0.000
I77 Other disorders of arteries and arterioles
0.835 0.165 0.000
M54.3 Sciatica
0.835 0.165 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.834 0.166 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.829 0.171 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.828 0.172 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.825 0.175 0.000
T51 Toxic effect of alcohol
0.824 0.176 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.821 0.179 0.000
M75.4 Impingement syndrome of shoulder
0.821 0.179 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.819 0.181 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.818 0.182 0.000
O26.8 Other specified pregnancy-related conditions
0.814 0.186 0.000
M20.3 Other deformity of hallux (acquired)
0.814 0.186 0.000
I63 Cerebral infarction
0.812 0.188 0.000
M05-M14 Inflammatory polyarthropathies
0.812 0.188 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.809 0.191 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.808 0.192 0.000
O20 Haemorrhage in early pregnancy
0.808 0.192 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.807 0.193 0.000
I67 Other cerebrovascular diseases
0.805 0.195 0.000
G40-G47 Episodic and paroxysmal disorders
0.804 0.196 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.803 0.196 0.000
O60-O75 Complications of labour and delivery
0.801 0.199 0.000
M50 Cervical disk disorders
0.801 0.199 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.801 0.199 0.000
T82.3 Mechanical complication of other vascular grafts
0.799 0.201 0.000
S62 Fracture at wrist and hand level
0.799 0.201 0.000
Y83.6 Removal of other organ (partial) (total)
0.799 0.201 0.000
M21 Other acquired deformities of limbs
0.798 0.202 0.000
M47.9 Spondylosis, unspecified
0.797 0.203 0.000
Chapter II Neoplasms
0.796 0.204 0.000
H53-H54 Visual disturbances and blindness
0.793 0.207 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.791 0.209 0.000
I47.2 Ventricular tachycardia
0.790 0.210 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.789 0.211 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.788 0.212 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.787 0.213 0.000
M80 Osteoporosis with pathological fracture
0.786 0.214 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.786 0.214 0.000
I73 Other peripheral vascular diseases
0.783 0.217 0.000
M17.0 Primary gonarthrosis, bilateral
0.782 0.218 0.000
M17.3 Other posttraumatic gonarthrosis
0.782 0.218 0.000
I50.1 Left ventricular failure
0.781 0.219 0.000
I46.9 Cardiac arrest, unspecified
0.781 0.219 0.000
M47.8 Other spondylosis
0.780 0.220 0.000
M19.0 Primary arthrosis of other joints
0.780 0.220 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.776 0.224 0.000
M00-M03 Infectious arthropathies
0.775 0.224 0.000
M75.5 Bursitis of shoulder
0.774 0.226 0.000
S68 Traumatic amputation of wrist and hand
0.770 0.230 0.000
X20-X29 Contact with venomous animals and plants
0.768 0.232 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.768 0.232 0.000
M46 Other inflammatory spondylopathies
0.766 0.234 0.000
M48 Other spondylopathies
0.764 0.236 0.000
S64.4 Injury of digital nerve of other finger
0.763 0.237 0.000
I34.0 Mitral (valve) insufficiency
0.763 0.237 0.000
M47.2 Other spondylosis with radiculopathy
0.760 0.240 0.000
W44 Foreign body entering into or through eye or natural orifice
0.760 0.240 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.758 0.242 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.757 0.242 0.000
I30 Acute pericarditis
0.757 0.243 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.757 0.243 0.000
Chapter XXII Codes for special purposes
0.756 0.244 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.756 0.244 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.754 0.246 0.000
S61 Open wound of wrist and hand
0.754 0.246 0.000
T40.2 Other opioids
0.753 0.247 0.000
S22.4 Multiple fractures of ribs
0.752 0.248 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.751 0.249 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.751 0.249 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.750 0.250 0.000
M24 Other specific joint derangements
0.748 0.251 0.000
M75.3 Calcific tendinitis of shoulder
0.747 0.253 0.000
M54.50 Low back pain (Multiple sites in spine)
0.746 0.254 0.000
V80-V89 Other land transport accidents
0.743 0.257 0.000
C60-C63 Malignant neoplasms of male genital organs
0.742 0.258 0.000
M81.98 Osteoporosis, unspecified (Other)
0.742 0.258 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.741 0.259 0.000
T51.0 Ethanol
0.741 0.259 0.000
H54 Blindness and low vision
0.740 0.260 0.000
M40-M43 Deforming dorsopathies
0.739 0.261 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.738 0.262 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.736 0.264 0.000
T79-T79 Certain early complications of trauma
0.736 0.264 0.000
S40-S49 Injuries to the shoulder and upper arm
0.734 0.266 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.734 0.266 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.733 0.267 0.000
M72 Fibroblastic disorders
0.731 0.269 0.000
T81 Complications of procedures, not elsewhere classified
0.731 0.269 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.730 0.270 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.729 0.271 0.000
G30-G32 Other degenerative diseases of the nervous system
0.727 0.273 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.727 0.273 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.726 0.274 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.726 0.274 0.000
M19.1 Posttraumatic arthrosis of other joints
0.725 0.275 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.725 0.275 0.000
V20-V29 Motorcycle rider injured in transport accident
0.724 0.276 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.723 0.277 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.723 0.277 0.000
S50-S59 Injuries to the elbow and forearm
0.722 0.278 0.000
H66 Suppurative and unspecified otitis media
0.722 0.278 0.000
M47.82 Other spondylosis (Cervical region)
0.721 0.279 0.000
S90-S99 Injuries to the ankle and foot
0.721 0.279 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.721 0.279 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.720 0.280 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.720 0.280 0.000
I42 Cardiomyopathy
0.719 0.281 0.000
O80-O84 Delivery
0.719 0.281 0.000
G44 Other headache syndromes
0.718 0.282 0.000
M77 Other enthesopathies
0.718 0.282 0.000
D00-D09 In situ neoplasms
0.718 0.282 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I67.9 Cerebrovascular disease, unspecified
0.717 0.283 0.000
M15 Polyarthrosis
0.717 0.283 0.000
M19.8 Other specified arthrosis
0.716 0.283 0.000
M19.2 Other secondary arthrosis
0.716 0.283 0.000
S70-S79 Injuries to the hip and thigh
0.716 0.284 0.000
S67 Crushing injury of wrist and hand
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
T87 Complications peculiar to reattachment and amputation
0.715 0.285 0.000
T86 Failure and rejection of transplanted organs and tissues
0.715 0.285 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.285 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.715 0.285 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
T36 Poisoning by systemic antibiotics
0.715 0.285 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.714 0.286 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.714 0.286 0.000
M75.0 Adhesive capsulitis of shoulder
0.714 0.286 0.000
S22.2 Fracture of sternum
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.286 0.000
I48 Atrial fibrillation and flutter
0.713 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.286 0.000
I40 Acute myocarditis
0.713 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.286 0.000
I37 Pulmonary valve disorders
0.713 0.286 0.000
I36 Nonrheumatic tricuspid valve disorders
0.713 0.286 0.000
I33 Acute and subacute endocarditis
0.713 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.286 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.713 0.286 0.000
M54.4 Lumbago with sciatica
0.713 0.287 0.000
M53 Other dorsopathies, not elsewhere classified
0.712 0.288 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.712 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V40-V49 Car occupant injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
S27 Injury of other and unspecified intrathoracic organs
0.710 0.290 0.000
I45.6 Preexcitation syndrome
0.709 0.291 0.000
F30-F39 Mood [affective] disorders
0.709 0.291 0.000
M54.8 Other dorsalgia
0.708 0.292 0.000
M54.6 Pain in thoracic spine
0.708 0.292 0.000
M54.0 Panniculitis affecting regions of neck and back
0.708 0.292 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.708 0.292 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.707 0.293 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.707 0.293 0.000
H80-H83 Diseases of inner ear
0.707 0.293 0.000
G20-G26 Extrapyramidal and movement disorders
0.706 0.294 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.706 0.294 0.000
F03 Unspecified dementia
0.705 0.295 0.000
H92 Otalgia and effusion of ear
0.705 0.295 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.703 0.297 0.000
I51.4 Myocarditis, unspecified
0.703 0.297 0.000
M25 Other joint disorders, not elsewhere classified
0.703 0.297 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.702 0.298 0.000
H30-H36 Disorders of choroid and retina
0.701 0.298 0.000
X60-X84 Intentional self-harm
0.701 0.299 0.000
M54.55 Low back pain (Thoracolumbar region)
0.701 0.299 0.000
M54.54 Low back pain-Thoracic
0.701 0.299 0.000
M54.53 Low back pain-Cervicothoracic
0.701 0.299 0.000
M54.52 Low back pain-Cervical
0.701 0.299 0.000
M54.51 Low back pain-Occipit-atl-axl
0.701 0.299 0.000
C61 Malignant neoplasm of prostate
0.701 0.299 0.000
Y45.0 Opioids and related analgesics
0.700 0.300 0.000
S22.3 Fracture of rib
0.700 0.300 0.000
S69 Other and unspecified injuries of wrist and hand
0.699 0.301 0.000
S65 Injury of blood vessels at wrist and hand level
0.699 0.301 0.000
S60 Superficial injury of wrist and hand
0.699 0.301 0.000
I47.0 Reentry ventricular arrhythmia
0.699 0.301 0.000
Y83.8 Other surgical procedures
0.698 0.302 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.698 0.302 0.000
T66-T78 Other and unspecified effects of external causes
0.698 0.302 0.000
T43.9 Psychotropic drug, unspecified
0.697 0.303 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.697 0.303 0.000
T43.6 Psychostimulants with abuse potential
0.697 0.303 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.697 0.303 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.697 0.303 0.000
O20.0 Threatened abortion
0.697 0.303 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.696 0.303 0.000
M34 Systemic sclerosis
0.696 0.303 0.000
M33 Dermatopolymyositis
0.696 0.303 0.000
M32 Systemic lupus erythematosus
0.696 0.303 0.000
M30 Polyarteritis nodosa and related conditions
0.696 0.303 0.000
T40.4 Other synthetic narcotics
0.696 0.304 0.000
I70 Atherosclerosis
0.696 0.304 0.000
W44.0 Home
0.694 0.306 0.000
V10-V19 Pedal cyclist injured in transport accident
0.694 0.306 0.000
I73.9 Peripheral vascular disease, unspecified
0.694 0.306 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.693 0.307 0.000
I74 Arterial embolism and thrombosis
0.693 0.307 0.000
T93 Sequelae of injuries of lower limb
0.693 0.307 0.000
M85 Other disorders of bone density and structure
0.692 0.308 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.692 0.308 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.691 0.309 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.691 0.309 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.691 0.309 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.691 0.309 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.691 0.309 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.691 0.309 0.000
M76 Enthesopathies of lower limb, excluding foot
0.691 0.309 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.691 0.309 0.000
C15-C26 Malignant neoplasms of digestive organs
0.690 0.310 0.000
I82 Other venous embolism and thrombosis
0.690 0.310 0.000
I51.9 Heart disease, unspecified
0.689 0.311 0.000
H71 Cholesteatoma of middle ear
0.689 0.311 0.000
F80-F89 Disorders of psychological development
0.688 0.312 0.000
T82.1 Mechanical complication of cardiac electronic device
0.686 0.314 0.000
M49 Spondylopathies in diseases classified elsewhere
0.685 0.315 0.000
I77.8 Other specified disorders of arteries and arterioles
0.685 0.315 0.000
M54.36 Sciatica (Lumbar region)
0.684 0.316 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.684 0.316 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.683 0.317 0.000
T63 Toxic effect of contact with venomous animals
0.683 0.317 0.000
H90 Conductive and sensorineural hearing loss
0.683 0.317 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.682 0.317 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.682 0.317 0.000
I87 Other disorders of veins
0.682 0.318 0.000
I61 Intracerebral haemorrhage
0.680 0.319 0.000
M54.1 Radiculopathy
0.680 0.320 0.000
M84 Disorders of continuity of bone
0.680 0.320 0.000
M83 Adult osteomalacia
0.680 0.320 0.000
M82 Osteoporosis in diseases classified elsewhere
0.680 0.320 0.000
H55-H59 Other disorders of eye and adnexa
0.680 0.320 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.679 0.321 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.679 0.321 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.679 0.321 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.679 0.321 0.000
T85.2 Mechanical complication of intraocular lens
0.679 0.321 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.679 0.321 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.679 0.321 0.000
L50-L54 Urticaria and erythema
0.678 0.322 0.000
M71 Other bursopathies
0.678 0.322 0.000
H74 Other disorders of middle ear and mastoid
0.677 0.323 0.000
M86-M90 Other osteopathies
0.676 0.324 0.000
M75.8 Other shoulder lesions
0.676 0.324 0.000
M75.9 Shoulder lesion, unspecified
0.676 0.324 0.000
M75.2 Bicipital tendinitis
0.676 0.324 0.000
S22.40 Multiple fractures of ribs (closed)
0.674 0.326 0.000
I49 Other cardiac arrhythmias
0.674 0.326 0.000
M17.5 Other secondary gonarthrosis
0.673 0.326 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.673 0.326 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.673 0.326 0.000
H70 Mastoiditis and related conditions
0.673 0.326 0.000
I45.2 Bifascicular block
0.671 0.328 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.671 0.329 0.000
T45.0 Antiallergic and antiemetic drugs
0.670 0.330 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.670 0.330 0.000
M18 Arthrosis of first carpometacarpal joint
0.668 0.331 0.000
S20 Superficial injury of thorax
0.668 0.332 0.000
O85-O92 Complications predominantly related to the puerperium
0.667 0.332 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.667 0.333 0.000
I31 Other diseases of pericardium
0.667 0.333 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.667 0.333 0.000
T51.9 Alcohol, unspecified
0.666 0.334 0.000
F00 Dementia in Alzheimer's disease
0.666 0.334 0.000
S64.3 Injury of digital nerve of thumb
0.665 0.335 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.664 0.335 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.664 0.335 0.000
S29 Other and unspecified injuries of thorax
0.664 0.336 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.664 0.336 0.000
S26 Injury of heart
0.664 0.336 0.000
S25 Injury of blood vessels of thorax
0.664 0.336 0.000
S24 Injury of nerves and spinal cord at thorax level
0.664 0.336 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.664 0.336 0.000
S21 Open wound of thorax
0.664 0.336 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.664 0.336 0.000
I72 Other aneurysm
0.664 0.336 0.000
M54.39 Sciatica (Site unspecified)
0.663 0.337 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.662 0.338 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.661 0.339 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.661 0.339 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.660 0.339 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.660 0.339 0.000
Y98 Lifestyle-related condition
0.660 0.339 0.000
Y97 Environmental-pollution-related condition
0.660 0.339 0.000
Y96 Work-related condition
0.660 0.339 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.660 0.340 0.000
I20-I25 Ischaemic heart diseases
0.660 0.340 0.000
H54.7 Unspecified visual loss
0.660 0.340 0.000
I51.8 Other ill-defined heart diseases
0.659 0.341 0.000
M06 Other rheumatoid arthritis
0.658 0.342 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.658 0.342 0.000
S62.5 Fracture of thumb
0.656 0.343 0.000
M31 Other necrotising vasculopathies
0.656 0.344 0.000
M50.2 Other cervical disk displacement
0.655 0.345 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.654 0.346 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.652 0.347 0.000
M47.1 Other spondylosis with myelopathy
0.652 0.348 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.652 0.348 0.000
M21.3 Wrist or foot drop (acquired)
0.651 0.349 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.651 0.349 0.000
M54.2 Cervicalgia
0.650 0.349 0.000
O29 Complications of anaesthesia during pregnancy
0.650 0.350 0.000
O28 Abnormal findings on antenatal screening of mother
0.650 0.350 0.000
O24 Diabetes mellitus in pregnancy
0.650 0.350 0.000
O23 Infections of genito-urinary tract in pregnancy
0.650 0.350 0.000
O22 Venous complications in pregnancy
0.650 0.350 0.000
O21 Excessive vomiting in pregnancy
0.650 0.350 0.000
O25 Malnutrition in pregnancy
0.650 0.350 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.649 0.351 0.000
I44 Atrioventricular and left bundle-branch block
0.649 0.351 0.000
T65 Toxic effect of other and unspecified substances
0.648 0.352 0.000
T62 Toxic effect of other noxious substances eaten as food
0.648 0.352 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.648 0.352 0.000
T60 Toxic effect of pesticides
0.648 0.352 0.000
T59 Toxic effect of other gases, fumes and vapours
0.648 0.352 0.000
T57 Toxic effect of other inorganic substances
0.648 0.352 0.000
T56 Toxic effect of metals
0.648 0.352 0.000
T54 Toxic effect of corrosive substances
0.648 0.352 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.648 0.352 0.000
T52 Toxic effect of organic solvents
0.648 0.352 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.648 0.352 0.000
T58 Toxic effect of carbon monoxide
0.648 0.352 0.000
T55 Toxic effect of soaps and detergents
0.648 0.352 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.648 0.352 0.000
F70-F79 Mental retardation
0.648 0.352 0.000
F60-F69 Disorders of adult personality and behaviour
0.648 0.352 0.000
F17.1 Harmful use
0.647 0.353 0.000
H54.0 Blindness, both eyes
0.647 0.353 0.000
G70-G73 Diseases of myoneural junction and muscle
0.646 0.354 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.646 0.354 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.644 0.356 0.000
M23.9 Internal derangement of knee, unspecified
0.643 0.357 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.643 0.357 0.000
M23.5 Chronic instability of knee
0.643 0.357 0.000
M23.1 Discoid meniscus (congenital)
0.643 0.357 0.000
M23.0 Cystic meniscus
0.643 0.357 0.000
M13 Other arthritis
0.642 0.358 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.642 0.358 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.642 0.358 0.000
H10-H13 Disorders of conjunctiva
0.641 0.359 0.000
Y44 Agents primarily affecting blood constituents
0.641 0.359 0.000
G43 Migraine
0.639 0.361 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.639 0.361 0.000
S80-S89 Injuries to the knee and lower leg
0.638 0.362 0.000
M23.4 Loose body in knee
0.637 0.362 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.636 0.364 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.636 0.364 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.636 0.364 0.000
I65.1 Occlusion and stenosis of basilar artery
0.636 0.364 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.636 0.364 0.000
T90 Sequelae of injuries of head
0.636 0.364 0.000
W00-W19 Falls
0.636 0.364 0.000
M65-M68 Disorders of synovium and tendon
0.636 0.364 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.635 0.365 0.000
D05 Carcinoma in situ of breast
0.635 0.365 0.000
F17.2 Dependence syndrome
0.634 0.366 0.000
M81.8 Other osteoporosis
0.633 0.366 0.000
M81.6 Localised osteoporosis [Lequesne]
0.633 0.366 0.000
M81.5 Idiopathic osteoporosis
0.633 0.366 0.000
M81.4 Drug-induced osteoporosis
0.633 0.366 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.633 0.366 0.000
M81.2 Osteoporosis of disuse
0.633 0.366 0.000
M81.1 Postoophorectomy osteoporosis
0.633 0.366 0.000
M81.0 Postmenopausal osteoporosis
0.633 0.366 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.633 0.367 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.633 0.367 0.000
Y45.1 Salicylates
0.632 0.368 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.631 0.369 0.000
Y83.5 Amputation of limb(s)
0.630 0.369 0.000
Y83.0 Surgical operation with transplant of whole organ
0.630 0.369 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.630 0.370 0.000
I77.1 Stricture of artery
0.630 0.370 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.629 0.371 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.629 0.371 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.629 0.371 0.000
T42.3 Barbiturates
0.629 0.371 0.000
T42.2 Succinimides and oxazolidinediones
0.629 0.371 0.000
T42.1 Iminostilbenes
0.629 0.371 0.000
T42.0 Hydantoin derivatives
0.629 0.371 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.628 0.372 0.000
M23.3 Other meniscus derangements
0.628 0.372 0.000
I05-I09 Chronic rheumatic heart diseases
0.627 0.372 0.000
H93 Other disorders of ear, not elsewhere classified
0.627 0.373 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.627 0.373 0.000
T40.8 Lysergide [LSD]
0.627 0.373 0.000
T40.7 Cannabis (derivatives)
0.627 0.373 0.000
T40.6 Other and unspecified narcotics
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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