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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117531052
log Bayes Factor = 28.3704
Chromosome 14   position 46,783,950  (GRCh37) Explore rs117531052 on Ensembl!
Variant rs117531052 is part of Cluster X0205

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.999 0.001 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.993 0.007 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.992 0.008 0.000
Z46 Fitting and adjustment of other devices
0.991 0.009 0.000
M20-M25 Other joint disorders
0.991 0.009 0.000
I60-I69 Cerebrovascular diseases
0.990 0.010 0.000
Z46.6 Fitting and adjustment of urinary device
0.986 0.014 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.986 0.014 0.000
Chapter I Certain infectious and parasitic diseases
0.985 0.015 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.981 0.019 0.000
I20-I25 Ischaemic heart diseases
0.980 0.020 0.000
M50-M54 Other dorsopathies
0.978 0.022 0.000
Z92 Personal history of medical treatment
0.975 0.025 0.000
Chapter V Mental and behavioural disorders
0.974 0.026 0.000
I84 Haemorrhoids
0.973 0.027 0.000
Chapter XI Diseases of the digestive system
0.972 0.028 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.971 0.029 0.000
Z93 Artificial opening status
0.970 0.030 0.000
T81 Complications of procedures, not elsewhere classified
0.970 0.030 0.000
Chapter VI Diseases of the nervous system
0.969 0.031 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.968 0.032 0.000
I30-I52 Other forms of heart disease
0.967 0.033 0.000
Z72 Problems related to lifestyle
0.964 0.036 0.000
Z87 Personal history of other diseases and conditions
0.961 0.039 0.000
Z90.1 Acquired absence of breast(s)
0.961 0.039 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.953 0.047 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.951 0.049 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.950 0.050 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.947 0.053 0.000
M45-M49 Spondylopathies
0.941 0.059 0.000
Z72.0 Tobacco use
0.941 0.059 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.938 0.062 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.935 0.065 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.934 0.066 0.000
I84.2 Internal haemorrhoids without complication
0.934 0.066 0.000
I84.6 Residual haemorrhoidal skin tags
0.932 0.068 0.000
M54 Dorsalgia
0.926 0.074 0.000
Chapter XX External causes of morbidity and mortality
0.924 0.076 0.000
Z41 Procedures for purposes other than remedying health state
0.923 0.077 0.000
M25 Other joint disorders, not elsewhere classified
0.920 0.080 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.918 0.082 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.914 0.086 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.912 0.088 0.000
I25 Chronic ischaemic heart disease
0.911 0.089 0.000
M15-M19 Arthrosis
0.908 0.092 0.000
Z80 Family history of malignant neoplasm
0.908 0.092 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.907 0.093 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.905 0.095 0.000
M05-M14 Inflammatory polyarthropathies
0.904 0.096 0.000
Z93.2 Ileostomy status
0.900 0.100 0.000
M51 Other intervertebral disk disorders
0.896 0.104 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.896 0.104 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.895 0.105 0.000
Z90.7 Acquired absence of genital organ(s)
0.894 0.106 0.000
M20 Acquired deformities of fingers and toes
0.894 0.106 0.000
Z01.8 Other specified special examinations
0.893 0.107 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.892 0.108 0.000
M48 Other spondylopathies
0.889 0.111 0.000
G40-G47 Episodic and paroxysmal disorders
0.888 0.112 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.887 0.113 0.000
I45 Other conduction disorders
0.887 0.113 0.000
I49 Other cardiac arrhythmias
0.887 0.113 0.000
Z13 Special screening examination for other diseases and disorders
0.886 0.114 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.886 0.114 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.885 0.115 0.000
I87 Other disorders of veins
0.885 0.115 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.884 0.116 0.000
Z12 Special screening examination for neoplasms
0.879 0.121 0.000
Z86 Personal history of certain other diseases
0.878 0.122 0.000
I63 Cerebral infarction
0.875 0.125 0.000
M65-M68 Disorders of synovium and tendon
0.874 0.126 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.874 0.126 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.873 0.127 0.000
M23 Internal derangement of knee
0.872 0.128 0.000
K35-K38 Diseases of appendix
0.872 0.128 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.870 0.130 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.868 0.132 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.868 0.132 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.867 0.133 0.000
M80-M85 Disorders of bone density and structure
0.867 0.133 0.000
Chapter XIV Diseases of the genitourinary system
0.865 0.135 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.864 0.136 0.000
K90-K93 Other diseases of the digestive system
0.864 0.136 0.000
B95-B98 Bacterial, viral and other infectious agents
0.863 0.137 0.000
K55-K64 Other diseases of intestines
0.862 0.138 0.000
I80 Phlebitis and thrombophlebitis
0.861 0.139 0.000
M25.7 Osteophyte
0.855 0.145 0.000
K08 Other disorders of teeth and supporting structures
0.854 0.146 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.853 0.147 0.000
I20 Angina pectoris
0.853 0.147 0.000
M48.0 Spinal stenosis
0.852 0.148 0.000
Z04 Examination and observation for other reasons
0.851 0.149 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.850 0.150 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.849 0.151 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.849 0.151 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.843 0.157 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.843 0.157 0.000
K04 Diseases of pulp and periapical tissues
0.843 0.157 0.000
M54.5 Low back pain
0.841 0.159 0.000
Z53.0 Procedure not carried out because of contraindication
0.841 0.159 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.840 0.160 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.838 0.162 0.000
I25.1 Atherosclerotic heart disease
0.837 0.163 0.000
Chapter VII Diseases of the eye and adnexa
0.836 0.164 0.000
N60-N64 Disorders of breast
0.835 0.165 0.000
B25-B34 Other viral diseases
0.830 0.170 0.000
Z50 Care involving use of rehabilitation procedures
0.829 0.171 0.000
Z90.5 Acquired absence of kidney
0.829 0.171 0.000
Z83 Family history of other specific disorders
0.828 0.172 0.000
S40-S49 Injuries to the shoulder and upper arm
0.828 0.172 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.825 0.175 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.824 0.176 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.823 0.177 0.000
F17.1 Harmful use
0.820 0.180 0.000
Z42 Follow-up care involving plastic surgery
0.820 0.180 0.000
Z93.6 Other artificial openings of urinary tract status
0.819 0.181 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.819 0.181 0.000
Z92.3 Personal history of irradiation
0.818 0.182 0.000
I45.1 Other and unspecified right bundle-branch block
0.817 0.182 0.000
B07 Viral warts
0.817 0.183 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.815 0.185 0.000
I60 Subarachnoid haemorrhage
0.815 0.185 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.811 0.189 0.000
Z86.0 Personal history of other neoplasms
0.810 0.190 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.809 0.191 0.000
G43 Migraine
0.807 0.193 0.000
Z95.3 Presence of xenogenic heart valve
0.805 0.195 0.000
I31 Other diseases of pericardium
0.805 0.195 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.804 0.196 0.000
Z90.3 Acquired absence of part of stomach
0.803 0.197 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.803 0.197 0.000
M20.1 Hallux valgus (acquired)
0.801 0.199 0.000
M06 Other rheumatoid arthritis
0.800 0.200 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.799 0.201 0.000
A30-A49 Other bacterial diseases
0.798 0.202 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.792 0.208 0.000
I34 Nonrheumatic mitral valve disorders
0.788 0.212 0.000
Z01.9 Special examination, unspecified
0.787 0.213 0.000
M25.77 Osteophyte (Ankle and foot)
0.787 0.213 0.000
I67 Other cerebrovascular diseases
0.786 0.214 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.786 0.214 0.000
Z97 Presence of other devices
0.785 0.214 0.000
M22 Disorders of patella
0.784 0.216 0.000
K59 Other functional intestinal disorders
0.784 0.216 0.000
Chapter XXII Codes for special purposes
0.781 0.219 0.000
I22 Subsequent myocardial infarction
0.781 0.219 0.000
I61 Intracerebral haemorrhage
0.779 0.221 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.778 0.222 0.000
Z87.1 Personal history of diseases of the digestive system
0.776 0.224 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.775 0.225 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.774 0.226 0.000
Z72.2 Drug use
0.774 0.226 0.000
Z98 Other postsurgical states
0.773 0.227 0.000
Z49 Care involving dialysis
0.773 0.227 0.000
I20.8 Other forms of angina pectoris
0.771 0.229 0.000
Z85 Personal history of malignant neoplasm
0.771 0.229 0.000
I36 Nonrheumatic tricuspid valve disorders
0.770 0.230 0.000
I27 Other pulmonary heart diseases
0.769 0.230 0.000
Z04.8 Examination and observation for other specified reasons
0.769 0.231 0.000
L20-L30 Dermatitis and eczema
0.769 0.231 0.000
M54.3 Sciatica
0.769 0.231 0.000
S10-S19 Injuries to the neck
0.769 0.231 0.000
G90-G99 Other disorders of the nervous system
0.768 0.232 0.000
K13 Other diseases of lip and oral mucosa
0.768 0.232 0.000
Z72.1 Alcohol use
0.768 0.232 0.000
Z93.3 Colostomy status
0.767 0.233 0.000
S80-S89 Injuries to the knee and lower leg
0.765 0.235 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.762 0.238 0.000
I87.8 Other specified disorders of veins
0.762 0.238 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.762 0.238 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.760 0.240 0.000
M67 Other disorders of synovium and tendon
0.760 0.240 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.760 0.240 0.000
Z93.0 Tracheostomy status
0.758 0.242 0.000
Z43 Attention to artificial openings
0.758 0.242 0.000
Chapter VIII Diseases of the ear and mastoid process
0.758 0.242 0.000
I24 Other acute ischaemic heart diseases
0.758 0.242 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.757 0.243 0.000
M17 Gonarthrosis [arthrosis of knee]
0.757 0.243 0.000
H53-H54 Visual disturbances and blindness
0.757 0.243 0.000
M19 Other arthrosis
0.757 0.243 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.757 0.243 0.000
Z82.3 Family history of stroke
0.757 0.243 0.000
I21 Acute myocardial infarction
0.757 0.243 0.000
Z45 Adjustment and management of implanted device
0.756 0.244 0.000
M54.59 Low back pain (Site unspecified)
0.756 0.244 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.755 0.245 0.000
K09 Cysts of oral region, not elsewhere classified
0.754 0.246 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.754 0.246 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.753 0.247 0.000
L40-L45 Papulosquamous disorders
0.753 0.247 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.751 0.249 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.751 0.249 0.000
K35 Acute appendicitis
0.751 0.249 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.750 0.250 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.749 0.251 0.000
G43.9 Migraine, unspecified
0.749 0.251 0.000
I65.2 Occlusion and stenosis of carotid artery
0.748 0.252 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.748 0.252 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.748 0.252 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.748 0.252 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.746 0.254 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.745 0.255 0.000
I84.8 Unspecified haemorrhoids with other complications
0.745 0.255 0.000
Z75 Problems related to medical facilities and other health care
0.744 0.256 0.000
M86-M90 Other osteopathies
0.744 0.256 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.744 0.256 0.000
K40-K46 Hernia
0.744 0.256 0.000
F41 Other anxiety disorders
0.744 0.256 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.744 0.256 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.742 0.258 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.742 0.258 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.741 0.259 0.000
K92 Other diseases of digestive system
0.741 0.259 0.000
M54.2 Cervicalgia
0.739 0.261 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.739 0.261 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.739 0.261 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.738 0.262 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.738 0.262 0.000
M51.2 Other specified intervertebral disk displacement
0.738 0.262 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.737 0.262 0.000
N17-N19 Renal failure
0.737 0.263 0.000
N61 Inflammatory disorders of breast
0.737 0.263 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.737 0.263 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.735 0.265 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.735 0.265 0.000
I49.9 Cardiac arrhythmia, unspecified
0.735 0.265 0.000
R21 Rash and other nonspecific skin eruption
0.734 0.266 0.000
Z95.1 Presence of aortocoronary bypass graft
0.733 0.267 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.733 0.267 0.000
I84.5 External haemorrhoids without complication
0.732 0.268 0.000
I62 Other nontraumatic intracranial haemorrhage
0.732 0.268 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.731 0.269 0.000
M48.06 Spinal stenosis (Lumbar region)
0.731 0.269 0.000
M31 Other necrotising vasculopathies
0.731 0.269 0.000
Chapter X Diseases of the respiratory system
0.731 0.269 0.000
F99-F99 Unspecified mental disorder
0.730 0.270 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.730 0.270 0.000
K59.0 Constipation
0.729 0.271 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.729 0.271 0.000
I87.1 Compression of vein
0.728 0.272 0.000
I44 Atrioventricular and left bundle-branch block
0.728 0.272 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.727 0.272 0.000
K11 Diseases of salivary glands
0.727 0.273 0.000
M47 Spondylosis
0.727 0.273 0.000
I47 Paroxysmal tachycardia
0.727 0.273 0.000
S20-S29 Injuries to the thorax
0.727 0.273 0.000
V40-V49 Car occupant injured in transport accident
0.727 0.273 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.726 0.274 0.000
M06.9 Rheumatoid arthritis, unspecified
0.725 0.275 0.000
I49.5 Sick sinus syndrome
0.725 0.275 0.000
K37 Unspecified appendicitis
0.724 0.276 0.000
M81 Osteoporosis without pathological fracture
0.724 0.276 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.723 0.277 0.000
M25.5 Pain in joint
0.722 0.278 0.000
Z73 Problems related to life-management difficulty
0.721 0.278 0.000
M17.1 Other primary gonarthrosis
0.721 0.279 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.721 0.279 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.721 0.279 0.000
M20.5 Other deformities of toe(s) (acquired)
0.721 0.279 0.000
M35 Other systemic involvement of connective tissue
0.721 0.279 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.720 0.280 0.000
M48.09 Spinal stenosis (Site unspecified)
0.720 0.280 0.000
B34 Viral infection of unspecified site
0.720 0.280 0.000
F17.2 Dependence syndrome
0.719 0.281 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.718 0.281 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.718 0.282 0.000
L05 Pilonidal cyst
0.718 0.282 0.000
N64 Other disorders of breast
0.718 0.282 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M54.1 Radiculopathy
0.716 0.284 0.000
Z54 Convalescence
0.716 0.284 0.000
Z52 Donors of organs and tissues
0.716 0.284 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.284 0.000
M40-M43 Deforming dorsopathies
0.716 0.284 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.716 0.284 0.000
M24 Other specific joint derangements
0.716 0.284 0.000
Z40 Prophylactic surgery
0.715 0.284 0.000
Z10 Routine general health check-up of defined subpopulation
0.715 0.285 0.000
I49.0 Ventricular fibrillation and flutter
0.715 0.285 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.714 0.286 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.713 0.287 0.000
T79-T79 Certain early complications of trauma
0.713 0.287 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
L03 Cellulitis
0.713 0.287 0.000
F40 Phobic anxiety disorders
0.713 0.287 0.000
Z12.5 Special screening examination for neoplasm of prostate
0.713 0.287 0.000
Z50.1 Other physical therapy
0.713 0.287 0.000
S90-S99 Injuries to the ankle and foot
0.712 0.288 0.000
T87 Complications peculiar to reattachment and amputation
0.712 0.288 0.000
T86 Failure and rejection of transplanted organs and tissues
0.712 0.288 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.712 0.288 0.000
G30-G32 Other degenerative diseases of the nervous system
0.711 0.288 0.000
I88 Nonspecific lymphadenitis
0.711 0.289 0.000
I86 Varicose veins of other sites
0.711 0.289 0.000
I85 Oesophageal varices
0.711 0.289 0.000
I82 Other venous embolism and thrombosis
0.711 0.289 0.000
I81 Portal vein thrombosis
0.711 0.289 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.711 0.289 0.000
Z46.8 Fitting and adjustment of other specified devices
0.711 0.289 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.711 0.289 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.711 0.289 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.711 0.289 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.711 0.289 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.711 0.289 0.000
Z46.1 Fitting and adjustment of hearing aid
0.711 0.289 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.711 0.289 0.000
Z99.1 Dependence on respirator
0.711 0.289 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.710 0.290 0.000
M34 Systemic sclerosis
0.710 0.290 0.000
M33 Dermatopolymyositis
0.710 0.290 0.000
M32 Systemic lupus erythematosus
0.710 0.290 0.000
M30 Polyarteritis nodosa and related conditions
0.710 0.290 0.000
M21 Other acquired deformities of limbs
0.710 0.290 0.000
Z74 Problems related to care-provider dependency
0.710 0.290 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.710 0.290 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.709 0.290 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.709 0.290 0.000
I34.0 Mitral (valve) insufficiency
0.709 0.290 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.709 0.291 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.708 0.292 0.000
I84.4 External haemorrhoids with other complications
0.708 0.292 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.707 0.292 0.000
T82.1 Mechanical complication of cardiac electronic device
0.707 0.293 0.000
Z93.1 Gastrostomy status
0.707 0.293 0.000
Z90.8 Acquired absence of other organs
0.707 0.293 0.000
Z90.0 Acquired absence of part of head and neck
0.707 0.293 0.000
M70-M79 Other soft tissue disorders
0.707 0.293 0.000
S70-S79 Injuries to the hip and thigh
0.706 0.294 0.000
B99-B99 Other infectious diseases
0.706 0.294 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.706 0.294 0.000
B65-B83 Helminthiases
0.706 0.294 0.000
B50-B64 Protozoal diseases
0.706 0.294 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.706 0.294 0.000
B15-B19 Viral hepatitis
0.706 0.294 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.706 0.294 0.000
A80-A89 Viral infections of the central nervous system
0.706 0.294 0.000
A75-A79 Rickettsioses
0.706 0.294 0.000
A70-A74 Other diseases caused by chlamydiae
0.706 0.294 0.000
A65-A69 Other spirochaetal diseases
0.706 0.294 0.000
A20-A28 Certain zoonotic bacterial diseases
0.706 0.294 0.000
A15-A19 Tuberculosis
0.706 0.294 0.000
N25-N29 Other disorders of kidney and ureter
0.705 0.295 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.705 0.295 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.705 0.295 0.000
Z86.7 Personal history of diseases of the circulatory system
0.705 0.295 0.000
Z76 Persons encountering health services in other circumstances
0.703 0.297 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.703 0.297 0.000
K08.3 Retained dental root
0.703 0.297 0.000
G51 Facial nerve disorders
0.703 0.297 0.000
I23 Certain current complications following acute myocardial infarction
0.702 0.297 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.702 0.298 0.000
I35 Nonrheumatic aortic valve disorders
0.702 0.298 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.702 0.298 0.000
M07 Psoriatic and enteropathic arthropathies
0.702 0.298 0.000
I31.3 Pericardial effusion (noninflammatory)
0.701 0.299 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.701 0.299 0.000
M53 Other dorsopathies, not elsewhere classified
0.701 0.299 0.000
Z92.9 Personal history of medical treatment, unspecified
0.699 0.301 0.000
Z92.8 Personal history of other medical treatment
0.699 0.301 0.000
Z92.5 Personal history of rehabilitation measures
0.699 0.301 0.000
Z92.0 Personal history of contraception
0.699 0.301 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.699 0.301 0.000
K90 Intestinal malabsorption
0.699 0.301 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.698 0.302 0.000
F80-F89 Disorders of psychological development
0.698 0.302 0.000
F70-F79 Mental retardation
0.698 0.302 0.000
F60-F69 Disorders of adult personality and behaviour
0.698 0.302 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.698 0.302 0.000
I84.3 External thrombosed haemorrhoids
0.697 0.302 0.000
I84.0 Internal thrombosed haemorrhoids
0.697 0.302 0.000
K04.5 Chronic apical periodontitis
0.697 0.303 0.000
Z99.3 Dependence on wheelchair
0.696 0.304 0.000
L10-L14 Bullous disorders
0.696 0.304 0.000
Z93.9 Artificial opening status, unspecified
0.696 0.304 0.000
Z93.8 Other artificial opening status
0.696 0.304 0.000
Z93.5 Cystostomy status
0.696 0.304 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.696 0.304 0.000
H53 Visual disturbances
0.696 0.304 0.000
T81.9 Unspecified complication of procedure
0.695 0.305 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.695 0.305 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.695 0.305 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.695 0.305 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.695 0.305 0.000
G70-G73 Diseases of myoneural junction and muscle
0.694 0.305 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.694 0.305 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.694 0.305 0.000
I52 Other heart disorders in diseases classified elsewhere
0.693 0.307 0.000
I48 Atrial fibrillation and flutter
0.693 0.307 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.693 0.307 0.000
I41 Myocarditis in diseases classified elsewhere
0.693 0.307 0.000
I40 Acute myocarditis
0.693 0.307 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.693 0.307 0.000
I37 Pulmonary valve disorders
0.693 0.307 0.000
I33 Acute and subacute endocarditis
0.693 0.307 0.000
I32 Pericarditis in diseases classified elsewhere
0.693 0.307 0.000
I30 Acute pericarditis
0.693 0.307 0.000
I38 Endocarditis, valve unspecified
0.693 0.307 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.693 0.307 0.000
M23.8 Other internal derangements of knee
0.693 0.307 0.000
M11 Other crystal arthropathies
0.692 0.308 0.000
S00-S09 Injuries to the head
0.692 0.308 0.000
R50-R69 General symptoms and signs
0.692 0.308 0.000
Z72.9 Problem related to lifestyle, unspecified
0.691 0.308 0.000
Z72.8 Other problems related to lifestyle
0.691 0.308 0.000
Z72.6 Gambling and betting
0.691 0.308 0.000
Z72.5 High-risk sexual behaviour
0.691 0.308 0.000
Z72.4 Inappropriate diet and eating habits
0.691 0.308 0.000
Z72.3 Lack of physical exercise
0.691 0.308 0.000
G40 Epilepsy
0.691 0.309 0.000
A00-A09 Intestinal infectious diseases
0.690 0.310 0.000
N62 Hypertrophy of breast
0.690 0.310 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.689 0.311 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.689 0.311 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.689 0.311 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.689 0.311 0.000
L08 Other local infections of skin and subcutaneous tissue
0.689 0.311 0.000
Z01.6 Radiological examination, not elsewhere classified
0.688 0.311 0.000
M18 Arthrosis of first carpometacarpal joint
0.688 0.312 0.000
H52 Disorders of refraction and accommodation
0.687 0.312 0.000
K62 Other diseases of anus and rectum
0.687 0.313 0.000
X60-X84 Intentional self-harm
0.687 0.313 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.687 0.313 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.686 0.314 0.000
M50 Cervical disk disorders
0.686 0.314 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.686 0.314 0.000
I49.4 Other and unspecified premature depolarisation
0.685 0.315 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.685 0.315 0.000
B35-B49 Mycoses
0.685 0.315 0.000
I74 Arterial embolism and thrombosis
0.684 0.316 0.000
K55 Vascular disorders of intestine
0.684 0.316 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.683 0.317 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.683 0.317 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.683 0.317 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.683 0.317 0.000
Z82.2 Family history of deafness and hearing loss
0.683 0.317 0.000
Z82.1 Family history of blindness and visual loss
0.683 0.317 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.683 0.317 0.000
M25.74 Osteophyte (Hand)
0.683 0.317 0.000
M16 Coxarthrosis [arthrosis of hip]
0.682 0.318 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.682 0.318 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.681 0.318 0.000
Z01.7 Laboratory examination
0.681 0.319 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.681 0.319 0.000
Z01.4 Gynaecological examination (general)(routine)
0.681 0.319 0.000
Z01.3 Examination of blood pressure
0.681 0.319 0.000
Z01.2 Dental examination
0.681 0.319 0.000
Z01.1 Examination of ears and hearing
0.681 0.319 0.000
Z01.0 Examination of eyes and vision
0.681 0.319 0.000
K04.6 Periapical abscess with sinus
0.680 0.320 0.000
Z96 Presence of other functional implants
0.680 0.320 0.000
M65 Synovitis and tenosynovitis
0.679 0.321 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.679 0.321 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.679 0.321 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.679 0.321 0.000
T82.3 Mechanical complication of other vascular grafts
0.679 0.321 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.679 0.321 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.679 0.321 0.000
M20.0 Deformity of finger(s)
0.679 0.321 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.679 0.321 0.000
M67.8 Other specified disorders of synovium and tendon
0.679 0.321 0.000
I45.6 Preexcitation syndrome
0.678 0.322 0.000
I69 Sequelae of cerebrovascular disease
0.676 0.324 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.676 0.324 0.000
M13 Other arthritis
0.676 0.324 0.000
M23.5 Chronic instability of knee
0.676 0.324 0.000
I46 Cardiac arrest
0.675 0.325 0.000
M49 Spondylopathies in diseases classified elsewhere
0.675 0.325 0.000
M46 Other inflammatory spondylopathies
0.675 0.325 0.000
M45 Ankylosing spondylitis
0.675 0.325 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.675 0.325 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.674 0.326 0.000
W20-W49 Exposure to inanimate mechanical forces
0.673 0.327 0.000
T66-T78 Other and unspecified effects of external causes
0.673 0.327 0.000
K10 Other diseases of jaws
0.673 0.327 0.000
K07 Dentofacial anomalies [including malocclusion]
0.673 0.327 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.673 0.327 0.000
K03 Other diseases of hard tissues of teeth
0.673 0.327 0.000
K00 Disorders of tooth development and eruption
0.673 0.327 0.000
L50-L54 Urticaria and erythema
0.673 0.327 0.000
M54.56 Low back pain (Lumbar region)
0.672 0.328 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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