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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11753254
log Bayes Factor = 12.8789
Chromosome 6   position 51,700,849  (GRCh37) Explore rs11753254 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
D22 Melanocytic naevi
0.998 0.002 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
E10-E14 Diabetes mellitus
0.991 0.009 0.000
I25.1 Atherosclerotic heart disease
0.990 0.010 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.988 0.012 0.000
E11 Non-insulin-dependent diabetes mellitus
0.985 0.015 0.000
I20 Angina pectoris
0.985 0.015 0.000
D10-D36 Benign neoplasms
0.983 0.017 0.000
Chapter II Neoplasms
0.979 0.021 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.978 0.022 0.000
E11.9 Without complications
0.969 0.031 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.960 0.040 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.958 0.042 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.951 0.049 0.000
M70-M79 Other soft tissue disorders
0.950 0.050 0.000
E20-E35 Disorders of other endocrine glands
0.950 0.050 0.000
D22.0 Melanocytic naevi of lip
0.949 0.051 0.000
I12 Hypertensive renal disease
0.947 0.053 0.000
W00-W19 Falls
0.946 0.054 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.945 0.055 0.000
I60-I69 Cerebrovascular diseases
0.944 0.056 0.000
R50-R69 General symptoms and signs
0.940 0.060 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.940 0.060 0.000
R53 Malaise and fatigue
0.938 0.062 0.000
E11.3 With ophthalmic complications
0.936 0.064 0.000
S60-S69 Injuries to the wrist and hand
0.935 0.065 0.000
M20-M25 Other joint disorders
0.933 0.067 0.000
M79.6 Pain in limb
0.927 0.073 0.000
I12.9 Hypertensive renal disease without renal failure
0.915 0.085 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.911 0.089 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.909 0.091 0.000
I20.0 Unstable angina
0.906 0.094 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.905 0.095 0.000
T42.4 Benzodiazepines
0.905 0.095 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.903 0.097 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.902 0.098 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.901 0.099 0.000
I20.1 Angina pectoris with documented spasm
0.898 0.102 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.893 0.107 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.891 0.109 0.000
I20.8 Other forms of angina pectoris
0.890 0.110 0.000
V40-V49 Car occupant injured in transport accident
0.889 0.111 0.000
D26 Other benign neoplasms of uterus
0.888 0.112 0.000
S00-S09 Injuries to the head
0.888 0.112 0.000
R55 Syncope and collapse
0.883 0.117 0.000
I60 Subarachnoid haemorrhage
0.879 0.121 0.000
Y52 Agents primarily affecting the cardiovascular system
0.879 0.121 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.877 0.123 0.000
M79.69 Pain in limb (Site unspecified)
0.877 0.123 0.000
D22.4 Melanocytic naevi of scalp and neck
0.876 0.124 0.000
M25 Other joint disorders, not elsewhere classified
0.874 0.126 0.000
R30-R39 Symptoms and signs involving the urinary system
0.874 0.126 0.000
M86-M90 Other osteopathies
0.873 0.127 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.867 0.133 0.000
R32 Unspecified urinary incontinence
0.867 0.133 0.000
M79.5 Residual foreign body in soft tissue
0.866 0.134 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.865 0.135 0.000
I63 Cerebral infarction
0.860 0.140 0.000
Chapter V Mental and behavioural disorders
0.860 0.140 0.000
X60-X84 Intentional self-harm
0.859 0.141 0.000
S70-S79 Injuries to the hip and thigh
0.858 0.142 0.000
I25.3 Aneurysm of heart
0.854 0.146 0.000
M79.1 Myalgia
0.854 0.146 0.000
D36 Benign neoplasm of other and unspecified sites
0.853 0.147 0.000
D28.0 Vulva
0.853 0.147 0.000
M79.7 Fibromyalgia
0.851 0.149 0.000
I61 Intracerebral haemorrhage
0.848 0.152 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.848 0.152 0.000
W13 Fall from, out of or through building or structure
0.843 0.157 0.000
R41.0 Disorientation, unspecified
0.843 0.157 0.000
C15-C26 Malignant neoplasms of digestive organs
0.842 0.158 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.840 0.160 0.000
R50 Fever of unknown origin
0.834 0.166 0.000
V10-V19 Pedal cyclist injured in transport accident
0.828 0.172 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.826 0.174 0.000
E14 Unspecified diabetes mellitus
0.825 0.175 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.825 0.175 0.000
M25.7 Osteophyte
0.824 0.176 0.000
R61 Hyperhidrosis
0.823 0.177 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.821 0.179 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.821 0.179 0.000
W50-W64 Exposure to animate mechanical forces
0.820 0.180 0.000
E65-E68 Obesity and other hyperalimentation
0.820 0.180 0.000
S61 Open wound of wrist and hand
0.819 0.181 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.818 0.182 0.000
Y57 Other and unspecified drugs and medicaments
0.816 0.184 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.813 0.187 0.000
M23 Internal derangement of knee
0.812 0.188 0.000
I05-I09 Chronic rheumatic heart diseases
0.810 0.190 0.000
E29 Testicular dysfunction
0.810 0.190 0.000
S10-S19 Injuries to the neck
0.810 0.190 0.000
I63.8 Other cerebral infarction
0.809 0.191 0.000
T14 Injury of unspecified body region
0.809 0.191 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.809 0.191 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.808 0.192 0.000
M79.62 Pain in limb (Upper arm)
0.808 0.192 0.000
M79.54 Residual foreign body in soft tissue (Hand)
0.806 0.194 0.000
M21 Other acquired deformities of limbs
0.805 0.195 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.805 0.195 0.000
D32 Benign neoplasm of meninges
0.804 0.196 0.000
T36 Poisoning by systemic antibiotics
0.804 0.196 0.000
C71 Malignant neoplasm of brain
0.802 0.198 0.000
D13.6 Pancreas
0.801 0.198 0.000
M30 Polyarteritis nodosa and related conditions
0.800 0.200 0.000
S09 Other and unspecified injuries of head
0.800 0.200 0.000
M79.70 Fibromyalgia (Multiple sites)
0.796 0.204 0.000
Y00-Y09 Assault
0.795 0.204 0.000
T90 Sequelae of injuries of head
0.794 0.206 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.792 0.208 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.791 0.209 0.000
E11.5 With peripheral circulatory complications
0.790 0.210 0.000
C15 Malignant neoplasm of oesophagus
0.787 0.213 0.000
M79.64 Pain in limb (Hand)
0.786 0.214 0.000
F20 Schizophrenia
0.786 0.214 0.000
W17 Other fall from one level to another
0.784 0.215 0.000
M23.3 Other meniscus derangements
0.784 0.216 0.000
E27 Other disorders of adrenal gland
0.784 0.216 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.782 0.218 0.000
T40.6 Other and unspecified narcotics
0.782 0.218 0.000
E70-E90 Metabolic disorders
0.782 0.218 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.781 0.219 0.000
X00-X09 Exposure to smoke, fire and flames
0.779 0.221 0.000
M24 Other specific joint derangements
0.777 0.223 0.000
M22 Disorders of patella
0.776 0.224 0.000
E13 Other specified diabetes mellitus
0.775 0.225 0.000
M79.9 Soft tissue disorder, unspecified
0.774 0.225 0.000
V80-V89 Other land transport accidents
0.773 0.227 0.000
D26.9 Uterus, unspecified
0.773 0.227 0.000
I73 Other peripheral vascular diseases
0.771 0.229 0.000
T51 Toxic effect of alcohol
0.771 0.229 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.771 0.229 0.000
W13.9 Unspecified place
0.770 0.230 0.000
D22.9 Melanocytic naevi, unspecified
0.769 0.231 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.768 0.232 0.000
D26.1 Corpus uteri
0.768 0.232 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.768 0.232 0.000
R60 Oedema, not elsewhere classified
0.766 0.234 0.000
E11.6 With other specified complications
0.765 0.235 0.000
D10 Benign neoplasm of mouth and pharynx
0.764 0.236 0.000
E23 Hypofunction and other disorders of pituitary gland
0.764 0.236 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.764 0.236 0.000
S62 Fracture at wrist and hand level
0.762 0.238 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.762 0.238 0.000
E11.0 With coma
0.761 0.239 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.759 0.241 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.759 0.241 0.000
I15 Secondary hypertension
0.758 0.241 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.758 0.242 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.758 0.242 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.757 0.243 0.000
F20.9 Schizophrenia, unspecified
0.757 0.243 0.000
M79.2 Neuralgia and neuritis, unspecified
0.755 0.245 0.000
D13.3 Other and unspecified parts of small intestine
0.754 0.246 0.000
S79 Other and unspecified injuries of hip and thigh
0.754 0.246 0.000
M79.19 Myalgia (Site unspecified)
0.753 0.247 0.000
I73.9 Peripheral vascular disease, unspecified
0.752 0.248 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.752 0.248 0.000
W06 Fall involving bed
0.751 0.249 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.751 0.249 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.750 0.250 0.000
T79-T79 Certain early complications of trauma
0.750 0.250 0.000
T14.0 Superficial injury of unspecified body region
0.749 0.251 0.000
T59 Toxic effect of other gases, fumes and vapours
0.749 0.251 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.748 0.252 0.000
I21 Acute myocardial infarction
0.748 0.252 0.000
R50.9 Fever, unspecified
0.748 0.252 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.748 0.252 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.747 0.253 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.746 0.254 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.744 0.256 0.000
W15 Fall from cliff
0.744 0.256 0.000
S00 Superficial injury of head
0.743 0.257 0.000
W11 Fall on and from ladder
0.743 0.257 0.000
I11 Hypertensive heart disease
0.742 0.257 0.000
S65 Injury of blood vessels at wrist and hand level
0.742 0.257 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.741 0.259 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.738 0.262 0.000
T91 Sequelae of injuries of neck and trunk
0.737 0.263 0.000
S69 Other and unspecified injuries of wrist and hand
0.735 0.264 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.735 0.265 0.000
M25.76 Osteophyte (Lower leg)
0.735 0.265 0.000
T00-T07 Injuries involving multiple body regions
0.734 0.266 0.000
I25.4 Coronary artery aneurysm
0.734 0.266 0.000
M40-M43 Deforming dorsopathies
0.733 0.267 0.000
W08 Fall involving other furniture
0.733 0.267 0.000
E26 Hyperaldosteronism
0.733 0.267 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.733 0.267 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.732 0.268 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.732 0.268 0.000
M86 Osteomyelitis
0.731 0.268 0.000
D11 Benign neoplasm of major salivary glands
0.731 0.269 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.730 0.270 0.000
S09.9 Unspecified injury of head
0.730 0.270 0.000
R80 Isolated proteinuria
0.729 0.271 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.729 0.271 0.000
R33 Retention of urine
0.728 0.272 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.728 0.272 0.000
W10 Fall on and from stairs and steps
0.726 0.274 0.000
T42.1 Iminostilbenes
0.726 0.274 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.726 0.274 0.000
S90-S99 Injuries to the ankle and foot
0.726 0.274 0.000
E16 Other disorders of pancreatic internal secretion
0.726 0.274 0.000
S05 Injury of eye and orbit
0.725 0.275 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.725 0.275 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.725 0.275 0.000
T58 Toxic effect of carbon monoxide
0.724 0.276 0.000
C82.4 Follicular lymphoma grade IIIb
0.724 0.276 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.724 0.276 0.000
X50-X57 Overexertion, travel and privation
0.724 0.276 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.723 0.277 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.721 0.278 0.000
M22.2 Patellofemoral disorders
0.721 0.279 0.000
R42 Dizziness and giddiness
0.720 0.280 0.000
E22 Hyperfunction of pituitary gland
0.720 0.280 0.000
R58 Haemorrhage, not elsewhere classified
0.720 0.280 0.000
M79.66 Pain in limb (Lower leg)
0.720 0.280 0.000
C15.5 Lower third of oesophagus
0.719 0.281 0.000
C81 Hodgkin's disease
0.718 0.282 0.000
M25.0 Haemarthrosis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
E34 Other endocrine disorders
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.717 0.283 0.000
S19 Other and unspecified injuries of neck
0.716 0.284 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.715 0.285 0.000
W14 Fall from tree
0.715 0.285 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.715 0.285 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X10-X19 Contact with heat and hot substances
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.287 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.287 0.000
E40-E46 Malnutrition
0.712 0.288 0.000
S68 Traumatic amputation of wrist and hand
0.711 0.289 0.000
E29.1 Testicular hypofunction
0.710 0.290 0.000
E12 Malnutrition-related diabetes mellitus
0.710 0.290 0.000
D31 Benign neoplasm of eye and adnexa
0.710 0.290 0.000
C69 Malignant neoplasm of eye and adnexa
0.710 0.290 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.709 0.290 0.000
M88 Paget's disease of bone [osteitis deformans]
0.709 0.291 0.000
M89 Other disorders of bone
0.709 0.291 0.000
I05 Rheumatic mitral valve diseases
0.709 0.291 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.709 0.291 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.709 0.291 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.709 0.291 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.709 0.291 0.000
T51.9 Alcohol, unspecified
0.707 0.293 0.000
R45 Symptoms and signs involving emotional state
0.707 0.293 0.000
E11.7 With multiple complications
0.706 0.294 0.000
V44.5 Driver injured in traffic accident
0.706 0.294 0.000
R61.9 Hyperhidrosis, unspecified
0.706 0.294 0.000
D15.0 Thymus
0.705 0.295 0.000
W05 Fall involving wheelchair
0.705 0.295 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.705 0.295 0.000
D19 Benign neoplasm of mesothelial tissue
0.705 0.295 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.704 0.296 0.000
M34 Systemic sclerosis
0.704 0.296 0.000
T66-T78 Other and unspecified effects of external causes
0.703 0.297 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.702 0.298 0.000
M76 Enthesopathies of lower limb, excluding foot
0.702 0.298 0.000
W55 Bitten or struck by other mammals
0.702 0.298 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.702 0.298 0.000
D16 Benign neoplasm of bone and articular cartilage
0.700 0.300 0.000
F30-F39 Mood [affective] disorders
0.699 0.301 0.000
D13.1 Stomach
0.699 0.301 0.000
Y57.9 Drug or medicament, unspecified
0.698 0.302 0.000
T90.9 Sequelae of unspecified injury of head
0.697 0.303 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.697 0.303 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.697 0.303 0.000
M79.60 Pain in limb (Multiple sites)
0.697 0.303 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.696 0.304 0.000
X78 Intentional self-harm by sharp object
0.694 0.306 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.693 0.307 0.000
E65 Localised adiposity
0.692 0.308 0.000
T11 Other injuries of upper limb, level unspecified
0.692 0.308 0.000
M21.2 Flexion deformity
0.691 0.309 0.000
F80-F89 Disorders of psychological development
0.690 0.310 0.000
E14.3 With ophthalmic complications
0.689 0.311 0.000
E11.8 With unspecified complications
0.689 0.311 0.000
D29 Benign neoplasm of male genital organs
0.687 0.313 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.687 0.313 0.000
V20-V29 Motorcycle rider injured in transport accident
0.687 0.313 0.000
Y59 Other and unspecified vaccines and biological substances
0.687 0.313 0.000
Y58 Bacterial vaccines
0.687 0.313 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.687 0.313 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.687 0.313 0.000
M33 Dermatopolymyositis
0.687 0.313 0.000
C71.1 Frontal lobe
0.686 0.314 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.685 0.315 0.000
M60-M63 Disorders of muscles
0.685 0.315 0.000
I72 Other aneurysm
0.682 0.318 0.000
M79.3 Panniculitis, unspecified
0.682 0.318 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.681 0.319 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.681 0.319 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.681 0.319 0.000
E32 Diseases of thymus
0.681 0.319 0.000
E31 Polyglandular dysfunction
0.681 0.319 0.000
E30 Disorders of puberty, not elsewhere classified
0.681 0.319 0.000
E25 Adrenogenital disorders
0.681 0.319 0.000
E20 Hypoparathyroidism
0.681 0.319 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.681 0.319 0.000
M23.5 Chronic instability of knee
0.680 0.320 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.679 0.321 0.000
S79.9 Unspecified injury of hip and thigh
0.679 0.321 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.679 0.321 0.000
M25.9 Joint disorder, unspecified
0.679 0.321 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.678 0.322 0.000
W12 Fall on and from scaffolding
0.678 0.322 0.000
W09 Fall involving playground equipment
0.678 0.322 0.000
W04 Fall while being carried or supported by other persons
0.678 0.322 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.678 0.322 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.678 0.322 0.000
W00 Fall on same level involving ice and snow
0.678 0.322 0.000
M25.4 Effusion of joint
0.678 0.322 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.678 0.322 0.000
M79.11 Myalgia (Shoulder region)
0.677 0.323 0.000
F31 Bipolar affective disorder
0.677 0.323 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.677 0.323 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.677 0.323 0.000
D28.1 Vagina
0.677 0.323 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.676 0.324 0.000
R57 Shock, not elsewhere classified
0.676 0.324 0.000
M25.74 Osteophyte (Hand)
0.676 0.324 0.000
C82.0 Small cleaved cell, follicular
0.674 0.326 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.674 0.326 0.000
R62 Lack of expected normal physiological development
0.674 0.326 0.000
R64 Cachexia
0.674 0.326 0.000
S67 Crushing injury of wrist and hand
0.674 0.326 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.674 0.326 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.674 0.326 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.674 0.326 0.000
T42.3 Barbiturates
0.674 0.326 0.000
T42.2 Succinimides and oxazolidinediones
0.674 0.326 0.000
T42.0 Hydantoin derivatives
0.674 0.326 0.000
Y57.6 Other diagnostic agents
0.673 0.327 0.000
T98 Sequelae of other and unspecified effects of external causes
0.672 0.327 0.000
S72 Fracture of femur
0.672 0.327 0.000
T36.0 Penicillins
0.672 0.328 0.000
C82.2 Large cell, follicular
0.671 0.329 0.000
M79.63 Pain in limb (Forearm)
0.671 0.329 0.000
E11.2 With renal complications
0.670 0.330 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.670 0.330 0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.670 0.330 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.669 0.331 0.000
M32 Systemic lupus erythematosus
0.669 0.331 0.000
W17.4 Street and highway
0.669 0.331 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.668 0.331 0.000
W07 Fall involving chair
0.668 0.332 0.000
E78.5 Hyperlipidaemia, unspecified
0.667 0.333 0.000
M21.3 Wrist or foot drop (acquired)
0.666 0.333 0.000
M25.79 Osteophyte (Site unspecified)
0.665 0.335 0.000
M79.68 Pain in limb (Other)
0.665 0.335 0.000
M79.61 Pain in limb (Shoulder region)
0.665 0.335 0.000
V48 Car occupant injured in noncollision transport accident
0.665 0.335 0.000
R54 Senility
0.664 0.336 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.663 0.337 0.000
R30 Pain associated with micturition
0.662 0.338 0.000
T63 Toxic effect of contact with venomous animals
0.662 0.338 0.000
M24.5 Contracture of joint
0.661 0.339 0.000
W20-W49 Exposure to inanimate mechanical forces
0.660 0.340 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.659 0.341 0.000
S80-S89 Injuries to the knee and lower leg
0.659 0.341 0.000
R61.0 Localised hyperhidrosis
0.658 0.342 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.658 0.342 0.000
X20-X29 Contact with venomous animals and plants
0.658 0.342 0.000
D32.9 Meninges, unspecified
0.657 0.343 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.657 0.343 0.000
I61.8 Other intracerebral haemorrhage
0.656 0.344 0.000
Y48 Anaesthetics and therapeutic gases
0.656 0.344 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.655 0.345 0.000
I95 Hypotension
0.655 0.345 0.000
E78.2 Mixed hyperlipidaemia
0.654 0.346 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.654 0.346 0.000
I25.5 Ischaemic cardiomyopathy
0.654 0.346 0.000
T65 Toxic effect of other and unspecified substances
0.653 0.346 0.000
T62 Toxic effect of other noxious substances eaten as food
0.653 0.346 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.653 0.346 0.000
T60 Toxic effect of pesticides
0.653 0.346 0.000
T57 Toxic effect of other inorganic substances
0.653 0.346 0.000
T54 Toxic effect of corrosive substances
0.653 0.346 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.653 0.346 0.000
T52 Toxic effect of organic solvents
0.653 0.346 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.653 0.346 0.000
T55 Toxic effect of soaps and detergents
0.653 0.346 0.000
I69 Sequelae of cerebrovascular disease
0.653 0.347 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.653 0.347 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.652 0.348 0.000
T90.5 Sequelae of intracranial injury
0.652 0.348 0.000
D28.9 Female genital organ, unspecified
0.652 0.348 0.000
D28.7 Other specified female genital organs
0.652 0.348 0.000
S00.9 Superficial injury of head, part unspecified
0.652 0.348 0.000
M00-M03 Infectious arthropathies
0.651 0.348 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.651 0.349 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.651 0.349 0.000
M90 Osteopathies in diseases classified elsewhere
0.651 0.349 0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)
0.650 0.350 0.000
I05.9 Mitral valve disease, unspecified
0.650 0.350 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.649 0.350 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.649 0.351 0.000
T56 Toxic effect of metals
0.649 0.351 0.000
D17 Benign lipomatous neoplasm
0.649 0.351 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.648 0.352 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.648 0.352 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.647 0.353 0.000
C95 Leukaemia of unspecified cell type
0.647 0.353 0.000
C94 Other leukaemias of specified cell type
0.647 0.353 0.000
C93 Monocytic leukaemia
0.647 0.353 0.000
C86 Other specified types of T/NK-cell lymphoma
0.647 0.353 0.000
F22 Persistent delusional disorders
0.647 0.353 0.000
D13.9 Ill-defined sites within the digestive system
0.647 0.353 0.000
D13.7 Endocrine pancreas
0.647 0.353 0.000
D13.4 Liver
0.647 0.353 0.000
S61.8 Open wound of other parts of wrist and hand
0.646 0.354 0.000
R50.8 Other specified fever
0.646 0.354 0.000
S50-S59 Injuries to the elbow and forearm
0.646 0.354 0.000
R43 Disturbances of smell and taste
0.645 0.355 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.645 0.355 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.645 0.355 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.645 0.355 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.644 0.356 0.000
Y52.1 Calcium-channel blockers
0.644 0.356 0.000
D28.2 Uterine tubes and ligaments
0.643 0.356 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.643 0.357 0.000
T45.0 Antiallergic and antiemetic drugs
0.643 0.357 0.000
R46 Symptoms and signs involving appearance and behaviour
0.643 0.357 0.000
M79.10 Myalgia (Multiple sites)
0.643 0.357 0.000
M91-M94 Chondropathies
0.642 0.358 0.000
T45.2 Vitamins, not elsewhere classified
0.642 0.358 0.000
S20-S29 Injuries to the thorax
0.642 0.358 0.000
D13.5 Extrahepatic bile ducts
0.642 0.358 0.000
M71 Other bursopathies
0.641 0.359 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.641 0.359 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.641 0.359 0.000
T09 Other injuries of spine and trunk, level unspecified
0.640 0.360 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.640 0.360 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.640 0.360 0.000
T12 Fracture of lower limb, level unspecified
0.640 0.360 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.640 0.360 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.640 0.360 0.000
T10 Fracture of upper limb, level unspecified
0.640 0.360 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.640 0.360 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.640 0.360 0.000
T08 Fracture of spine, level unspecified
0.640 0.360 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.640 0.360 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.640 0.360 0.000
S62.5 Fracture of thumb
0.640 0.360 0.000
E24 Cushing's syndrome
0.639 0.361 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.638 0.361 0.000
C70 Malignant neoplasm of meninges
0.638 0.361 0.000
S32 Fracture of lumbar spine and pelvis
0.638 0.362 0.000
V47 Car occupant injured in collision with fixed or stationary object
0.637 0.363 0.000
V46 Car occupant injured in collision with other nonmotor vehicle
0.637 0.363 0.000
V45 Car occupant injured in collision with railway train or railway vehicle
0.637 0.363 0.000
V42 Car occupant injured in collision with two- or three-wheeled motor vehicle
0.637 0.363 0.000
V41 Car occupant injured in collision with pedal cycle
0.637 0.363 0.000
V40 Car occupant injured in collision with pedestrian or animal
0.637 0.363 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.637 0.363 0.000
D26.7 Other parts of uterus
0.637 0.363 0.000
S19.9 Unspecified injury of neck
0.637 0.363 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.637 0.363 0.000
S08 Traumatic amputation of part of head
0.636 0.364 0.000
S07 Crushing injury of head
0.636 0.364 0.000
S04 Injury of cranial nerves
0.636 0.364 0.000
R81 Glycosuria
0.636 0.364 0.000
D13.0 Oesophagus
0.636 0.364 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.636 0.364 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.636 0.364 0.000
E21.0 Primary hyperparathyroidism
0.636 0.364 0.000
R50.1 Persistent fever
0.636 0.364 0.000
C15.9 Oesophagus, unspecified
0.635 0.365 0.000
M23.0 Cystic meniscus
0.635 0.365 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.635 0.365 0.000
R68 Other general symptoms and signs
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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