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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117673410
log Bayes Factor = 14.9552
Chromosome 14   position 50,519,643  (GRCh37) Explore rs117673410 on Ensembl!
Variant rs117673410 is part of Cluster X0081

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
1.000 0.000 0.000
R13 Dysphagia
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
R50-R69 General symptoms and signs
0.993 0.007 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.990 0.010 0.000
R69 Unknown and unspecified causes of morbidity
0.988 0.012 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.985 0.015 0.000
R10 Abdominal and pelvic pain
0.982 0.018 0.000
J90-J94 Other diseases of pleura
0.980 0.020 0.000
Chapter VII Diseases of the eye and adnexa
0.979 0.021 0.000
J90 Pleural effusion, not elsewhere classified
0.972 0.028 0.000
Chapter VI Diseases of the nervous system
0.969 0.031 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.968 0.032 0.000
R10.1 Pain localised to upper abdomen
0.967 0.033 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.965 0.035 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.965 0.035 0.000
Chapter VIII Diseases of the ear and mastoid process
0.962 0.038 0.000
J95-J99 Other diseases of the respiratory system
0.961 0.039 0.000
Chapter XXI Factors influencing health status and contact with health services
0.956 0.044 0.000
H30-H36 Disorders of choroid and retina
0.950 0.050 0.000
R55 Syncope and collapse
0.947 0.053 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.943 0.057 0.000
O60-O75 Complications of labour and delivery
0.943 0.057 0.000
J98 Other respiratory disorders
0.936 0.064 0.000
Z86 Personal history of certain other diseases
0.936 0.064 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.933 0.067 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.932 0.068 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.930 0.070 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.929 0.071 0.000
R00 Abnormalities of heart beat
0.926 0.074 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.917 0.083 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.916 0.084 0.000
Z86.4 Personal history of psychoactive substance abuse
0.914 0.086 0.000
H35 Other retinal disorders
0.912 0.088 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.907 0.093 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.905 0.095 0.000
Chapter XIV Diseases of the genitourinary system
0.901 0.099 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.896 0.104 0.000
Y83.6 Removal of other organ (partial) (total)
0.891 0.109 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.884 0.116 0.000
H90-H95 Other disorders of ear
0.884 0.116 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.877 0.123 0.000
L03 Cellulitis
0.875 0.125 0.000
O63 Long labour
0.871 0.129 0.000
Chapter V Mental and behavioural disorders
0.867 0.133 0.000
R05 Cough
0.864 0.136 0.000
R00.0 Tachycardia, unspecified
0.861 0.139 0.000
J98.4 Other disorders of lung
0.858 0.142 0.000
N25-N29 Other disorders of kidney and ureter
0.856 0.144 0.000
H53-H54 Visual disturbances and blindness
0.855 0.145 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.854 0.146 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.854 0.146 0.000
S40-S49 Injuries to the shoulder and upper arm
0.851 0.149 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.851 0.149 0.000
J98.1 Pulmonary collapse
0.849 0.151 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.849 0.151 0.000
N10-N16 Renal tubulo-interstitial diseases
0.848 0.152 0.000
M70-M79 Other soft tissue disorders
0.844 0.156 0.000
L03.1 Cellulitis of other parts of limb
0.842 0.158 0.000
J09-J18 Influenza and pneumonia
0.842 0.158 0.000
S00-S09 Injuries to the head
0.840 0.160 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.834 0.166 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.831 0.169 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.829 0.171 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.827 0.173 0.000
S50-S59 Injuries to the elbow and forearm
0.826 0.174 0.000
R10.3 Pain localised to other parts of lower abdomen
0.825 0.175 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.825 0.175 0.000
H43-H45 Disorders of vitreous body and globe
0.824 0.176 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.824 0.176 0.000
R21 Rash and other nonspecific skin eruption
0.823 0.177 0.000
Chapter II Neoplasms
0.818 0.182 0.000
L50-L54 Urticaria and erythema
0.816 0.184 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.815 0.185 0.000
H35.8 Other specified retinal disorders
0.814 0.186 0.000
V80-V89 Other land transport accidents
0.813 0.187 0.000
R10.2 Pelvic and perineal pain
0.811 0.189 0.000
G35 Multiple sclerosis
0.811 0.189 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.810 0.190 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.810 0.190 0.000
Chapter XXII Codes for special purposes
0.810 0.190 0.000
N13 Obstructive and reflux uropathy
0.809 0.191 0.000
R56 Convulsions, not elsewhere classified
0.808 0.192 0.000
H33 Retinal detachments and breaks
0.807 0.193 0.000
M75 Shoulder lesions
0.806 0.194 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.805 0.195 0.000
O63.1 Prolonged second stage (of labour)
0.805 0.195 0.000
H35.3 Degeneration of macula and posterior pole
0.804 0.196 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.801 0.198 0.000
R68 Other general symptoms and signs
0.801 0.199 0.000
Z87 Personal history of other diseases and conditions
0.800 0.200 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.797 0.203 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.794 0.206 0.000
Chapter XI Diseases of the digestive system
0.794 0.206 0.000
R11 Nausea and vomiting
0.793 0.207 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.791 0.209 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.791 0.209 0.000
R17 Unspecified jaundice
0.789 0.211 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.789 0.211 0.000
H80-H83 Diseases of inner ear
0.788 0.211 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.788 0.212 0.000
J60-J70 Lung diseases due to external agents
0.786 0.214 0.000
E70-E90 Metabolic disorders
0.783 0.217 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.781 0.219 0.000
J30-J39 Other diseases of upper respiratory tract
0.780 0.220 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.779 0.221 0.000
Z86.7 Personal history of diseases of the circulatory system
0.777 0.223 0.000
Z97 Presence of other devices
0.776 0.224 0.000
K80 Cholelithiasis
0.776 0.224 0.000
O72 Postpartum haemorrhage
0.776 0.224 0.000
R00.2 Palpitations
0.775 0.225 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.775 0.225 0.000
L89 Decubitus ulcer
0.774 0.226 0.000
R02 Gangrene, not elsewhere classified
0.773 0.227 0.000
Z83 Family history of other specific disorders
0.772 0.228 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.771 0.229 0.000
Y43 Primarily systemic agents
0.770 0.230 0.000
S00 Superficial injury of head
0.769 0.231 0.000
L60-L75 Disorders of skin appendages
0.769 0.231 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.767 0.233 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.767 0.233 0.000
H91 Other hearing loss
0.765 0.235 0.000
G90-G99 Other disorders of the nervous system
0.765 0.235 0.000
W20-W49 Exposure to inanimate mechanical forces
0.764 0.236 0.000
H65-H75 Diseases of middle ear and mastoid
0.763 0.237 0.000
F10.1 Harmful use
0.763 0.237 0.000
Z93 Artificial opening status
0.763 0.237 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.762 0.238 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.762 0.238 0.000
L85 Other epidermal thickening
0.759 0.241 0.000
H60-H62 Diseases of external ear
0.757 0.243 0.000
M05-M14 Inflammatory polyarthropathies
0.757 0.243 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.756 0.244 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.754 0.246 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.752 0.248 0.000
S90-S99 Injuries to the ankle and foot
0.752 0.248 0.000
Z90.7 Acquired absence of genital organ(s)
0.751 0.249 0.000
J98.8 Other specified respiratory disorders
0.749 0.251 0.000
R60 Oedema, not elsewhere classified
0.746 0.254 0.000
S80-S89 Injuries to the knee and lower leg
0.746 0.254 0.000
Z90.2 Acquired absence of lung [part of]
0.746 0.254 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.745 0.255 0.000
S20-S29 Injuries to the thorax
0.744 0.256 0.000
H93 Other disorders of ear, not elsewhere classified
0.744 0.256 0.000
M86-M90 Other osteopathies
0.743 0.257 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.742 0.257 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.742 0.258 0.000
L84 Corns and callosities
0.741 0.259 0.000
R80 Isolated proteinuria
0.740 0.260 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.740 0.260 0.000
G37 Other demyelinating diseases of central nervous system
0.739 0.260 0.000
H54 Blindness and low vision
0.739 0.261 0.000
H35.7 Separation of retinal layers
0.738 0.262 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.737 0.263 0.000
R00.1 Bradycardia, unspecified
0.736 0.264 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.736 0.264 0.000
N13.3 Other and unspecified hydronephrosis
0.736 0.264 0.000
C64-C68 Malignant neoplasms of urinary tract
0.735 0.265 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.735 0.265 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.734 0.266 0.000
K83 Other diseases of biliary tract
0.731 0.269 0.000
L20-L30 Dermatitis and eczema
0.730 0.270 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.729 0.271 0.000
G70-G73 Diseases of myoneural junction and muscle
0.728 0.272 0.000
S52 Fracture of forearm
0.727 0.273 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.724 0.276 0.000
O80-O84 Delivery
0.724 0.276 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.724 0.276 0.000
H10-H13 Disorders of conjunctiva
0.723 0.277 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.723 0.277 0.000
R52 Pain, not elsewhere classified
0.722 0.278 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.722 0.278 0.000
G82 Paraplegia and tetraplegia
0.721 0.279 0.000
M80-M85 Disorders of bone density and structure
0.719 0.281 0.000
C15-C26 Malignant neoplasms of digestive organs
0.718 0.282 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y84.2 Radiological procedure and radiotherapy
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X60-X84 Intentional self-harm
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V20-V29 Motorcycle rider injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
H55-H59 Other disorders of eye and adnexa
0.714 0.286 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.713 0.287 0.000
H43 Disorders of vitreous body
0.713 0.287 0.000
N28.1 Cyst of kidney, acquired
0.713 0.287 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.712 0.288 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.712 0.288 0.000
R62 Lack of expected normal physiological development
0.712 0.288 0.000
R57 Shock, not elsewhere classified
0.712 0.288 0.000
R64 Cachexia
0.712 0.288 0.000
R58 Haemorrhage, not elsewhere classified
0.712 0.288 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.712 0.288 0.000
R20 Disturbances of skin sensation
0.712 0.288 0.000
V10-V19 Pedal cyclist injured in transport accident
0.711 0.289 0.000
L10-L14 Bullous disorders
0.710 0.290 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.709 0.291 0.000
O85-O92 Complications predominantly related to the puerperium
0.706 0.294 0.000
M75.4 Impingement syndrome of shoulder
0.706 0.294 0.000
R10.0 Acute abdomen
0.704 0.296 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.704 0.296 0.000
Z89 Acquired absence of limb
0.704 0.296 0.000
E86 Volume depletion
0.703 0.297 0.000
J94 Other pleural conditions
0.703 0.297 0.000
J91 Pleural effusion in conditions classified elsewhere
0.703 0.297 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.702 0.298 0.000
L03.2 Cellulitis of face
0.700 0.300 0.000
S43.0 Dislocation of shoulder joint
0.699 0.301 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.698 0.302 0.000
N99-N99 Other disorders of the genitourinary system
0.697 0.303 0.000
N00-N08 Glomerular diseases
0.697 0.303 0.000
O00-O08 Pregnancy with abortive outcome
0.695 0.305 0.000
L91 Hypertrophic disorders of skin
0.695 0.305 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.695 0.305 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.695 0.305 0.000
K70-K77 Diseases of liver
0.695 0.305 0.000
Y84.0 Cardiac catheterisation
0.693 0.307 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.693 0.307 0.000
L53 Other erythematous conditions
0.692 0.308 0.000
T79-T79 Certain early complications of trauma
0.692 0.308 0.000
T33-T35 Frostbite
0.692 0.308 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.692 0.308 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.692 0.308 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.692 0.308 0.000
T00-T07 Injuries involving multiple body regions
0.692 0.308 0.000
S10-S19 Injuries to the neck
0.692 0.308 0.000
J33 Nasal polyp
0.690 0.310 0.000
H50 Other strabismus
0.690 0.310 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.689 0.311 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.689 0.311 0.000
J96 Respiratory failure, not elsewhere classified
0.689 0.311 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.689 0.311 0.000
Z83.5 Family history of eye and ear disorders
0.689 0.311 0.000
Y85 Sequelae of transport accidents
0.688 0.312 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.687 0.312 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.687 0.313 0.000
E20-E35 Disorders of other endocrine glands
0.686 0.314 0.000
L03.9 Cellulitis, unspecified
0.685 0.315 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.685 0.315 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.685 0.315 0.000
S06 Intracranial injury
0.685 0.315 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.684 0.315 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.684 0.316 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.683 0.316 0.000
H36 Retinal disorders in diseases classified elsewhere
0.683 0.317 0.000
M20-M25 Other joint disorders
0.682 0.318 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.682 0.318 0.000
M40-M43 Deforming dorsopathies
0.681 0.319 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.681 0.319 0.000
H31 Other disorders of choroid
0.681 0.319 0.000
H30 Chorioretinal inflammation
0.681 0.319 0.000
Y83.3 Surgical operation with formation of external stoma
0.680 0.319 0.000
H91.9 Hearing loss, unspecified
0.681 0.319 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.680 0.320 0.000
O63.0 Prolonged first stage (of labour)
0.680 0.320 0.000
S00.1 Contusion of eyelid and periocular area
0.679 0.321 0.000
E10-E14 Diabetes mellitus
0.679 0.321 0.000
M75.5 Bursitis of shoulder
0.679 0.321 0.000
H81 Disorders of vestibular function
0.678 0.322 0.000
J18 Pneumonia, organism unspecified
0.677 0.323 0.000
L08 Other local infections of skin and subcutaneous tissue
0.677 0.323 0.000
M65-M68 Disorders of synovium and tendon
0.676 0.324 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.676 0.324 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.676 0.324 0.000
L94 Other localised connective tissue disorders
0.676 0.324 0.000
L93 Lupus erythematosus
0.676 0.324 0.000
L87 Transepidermal elimination disorders
0.676 0.324 0.000
L88 Pyoderma gangrenosum
0.676 0.324 0.000
L86 Keratoderma in diseases classified elsewhere
0.676 0.324 0.000
L83 Acanthosis nigricans
0.676 0.324 0.000
L80 Vitiligo
0.676 0.324 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.676 0.324 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.676 0.324 0.000
O74 Complications of anaesthesia during labour and delivery
0.676 0.324 0.000
O73 Retained placenta and membranes, without haemorrhage
0.676 0.324 0.000
O71 Other obstetric trauma
0.676 0.324 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.676 0.324 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.676 0.324 0.000
O66 Other obstructed labour
0.676 0.324 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.676 0.324 0.000
O62 Abnormalities of forces of labour
0.676 0.324 0.000
O61 Failed induction of labour
0.676 0.324 0.000
O60 Preterm delivery
0.676 0.324 0.000
R56.8 Other and unspecified convulsions
0.675 0.325 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.675 0.325 0.000
R50 Fever of unknown origin
0.675 0.325 0.000
Y43.3 Other antineoplastic drugs
0.674 0.326 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.674 0.326 0.000
Z60 Problems related to social environment
0.673 0.326 0.000
Y57 Other and unspecified drugs and medicaments
0.673 0.327 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.673 0.327 0.000
J98.9 Respiratory disorder, unspecified
0.671 0.329 0.000
J98.6 Disorders of diaphragm
0.671 0.329 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.671 0.329 0.000
J98.3 Compensatory emphysema
0.671 0.329 0.000
J98.2 Interstitial emphysema
0.671 0.329 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.671 0.329 0.000
M75.0 Adhesive capsulitis of shoulder
0.670 0.330 0.000
R06 Abnormalities of breathing
0.670 0.330 0.000
G57 Mononeuropathies of lower limb
0.670 0.330 0.000
H53 Visual disturbances
0.670 0.330 0.000
R23 Other skin changes
0.669 0.331 0.000
Z84 Family history of other conditions
0.668 0.332 0.000
Z81 Family history of mental and behavioural disorders
0.668 0.332 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.668 0.332 0.000
R19.5 Other fecal abnormalities
0.668 0.332 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.668 0.332 0.000
G30-G32 Other degenerative diseases of the nervous system
0.668 0.332 0.000
T91 Sequelae of injuries of neck and trunk
0.667 0.333 0.000
Y83.5 Amputation of limb(s)
0.666 0.333 0.000
Y83.0 Surgical operation with transplant of whole organ
0.666 0.333 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.666 0.334 0.000
E50-E64 Other nutritional deficiencies
0.666 0.334 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.665 0.335 0.000
J00-J06 Acute upper respiratory infections
0.665 0.335 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.665 0.335 0.000
C67 Malignant neoplasm of bladder
0.665 0.335 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.664 0.336 0.000
H34 Retinal vascular occlusions
0.664 0.336 0.000
R68.8 Other specified general symptoms and signs
0.664 0.336 0.000
H90 Conductive and sensorineural hearing loss
0.664 0.336 0.000
Z96 Presence of other functional implants
0.664 0.336 0.000
Z97.8 Presence of other specified devices
0.663 0.336 0.000
H52 Disorders of refraction and accommodation
0.663 0.337 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.663 0.337 0.000
K83.8 Other specified diseases of biliary tract
0.662 0.338 0.000
J92 Pleural plaque
0.661 0.338 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.661 0.339 0.000
Y44 Agents primarily affecting blood constituents
0.660 0.340 0.000
Z90.5 Acquired absence of kidney
0.659 0.341 0.000
L04 Acute lymphadenitis
0.657 0.343 0.000
L01 Impetigo
0.657 0.343 0.000
L00 Staphylococcal scalded skin syndrome
0.657 0.343 0.000
M91-M94 Chondropathies
0.657 0.343 0.000
M60-M63 Disorders of muscles
0.657 0.343 0.000
M00-M03 Infectious arthropathies
0.657 0.343 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.656 0.344 0.000
H35.9 Retinal disorder, unspecified
0.654 0.346 0.000
H35.6 Retinal haemorrhage
0.654 0.346 0.000
H35.5 Hereditary retinal dystrophy
0.654 0.346 0.000
H35.4 Peripheral retinal degeneration
0.654 0.346 0.000
H35.2 Other proliferative retinopathy
0.654 0.346 0.000
H35.1 Retinopathy of prematurity
0.654 0.346 0.000
H35.0 Background retinopathy and retinal vascular changes
0.654 0.346 0.000
R59 Enlarged lymph nodes
0.653 0.346 0.000
M77 Other enthesopathies
0.653 0.347 0.000
L89.1 Stage II decubitus ulcer
0.653 0.347 0.000
H33.0 Retinal detachment with retinal break
0.652 0.348 0.000
H40-H42 Glaucoma
0.652 0.348 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.651 0.349 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.650 0.350 0.000
O97 Death from sequelae of direct obstetric causes
0.650 0.350 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.650 0.350 0.000
O95 Obstetric death of unspecified cause
0.650 0.350 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.650 0.350 0.000
J30 Vasomotor and allergic rhinitis
0.650 0.350 0.000
Y59 Other and unspecified vaccines and biological substances
0.649 0.351 0.000
Y58 Bacterial vaccines
0.649 0.351 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.649 0.351 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.649 0.351 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.649 0.351 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.649 0.351 0.000
Y52 Agents primarily affecting the cardiovascular system
0.649 0.351 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.649 0.351 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.649 0.351 0.000
Y48 Anaesthetics and therapeutic gases
0.649 0.351 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.649 0.351 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.649 0.351 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.649 0.351 0.000
Y40 Systemic antibiotics
0.649 0.351 0.000
Z93.1 Gastrostomy status
0.649 0.351 0.000
L40-L45 Papulosquamous disorders
0.649 0.351 0.000
S60-S69 Injuries to the wrist and hand
0.648 0.352 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.648 0.352 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.648 0.352 0.000
W00-W19 Falls
0.648 0.352 0.000
S81 Open wound of lower leg
0.647 0.353 0.000
H92 Otalgia and effusion of ear
0.645 0.355 0.000
H93.1 Tinnitus
0.643 0.357 0.000
G36 Other acute disseminated demyelination
0.642 0.357 0.000
L81 Other disorders of pigmentation
0.642 0.358 0.000
T66-T78 Other and unspecified effects of external causes
0.642 0.358 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.642 0.358 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.642 0.358 0.000
F10.2 Dependence syndrome
0.639 0.361 0.000
G20-G26 Extrapyramidal and movement disorders
0.639 0.361 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.638 0.362 0.000
S70-S79 Injuries to the hip and thigh
0.638 0.362 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.637 0.363 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.636 0.364 0.000
J69 Pneumonitis due to solids and liquids
0.635 0.365 0.000
R61 Hyperhidrosis
0.635 0.365 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.634 0.366 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.634 0.366 0.000
H43.8 Other disorders of vitreous body
0.632 0.368 0.000
S42 Fracture of shoulder and upper arm
0.632 0.368 0.000
H33.3 Retinal breaks without detachment
0.631 0.369 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.631 0.369 0.000
Y83.9 Surgical procedure, unspecified
0.630 0.370 0.000
K85 Acute pancreatitis
0.629 0.371 0.000
E40-E46 Malnutrition
0.629 0.371 0.000
S52.6 Fracture of lower end of both ulna and radius
0.629 0.371 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.628 0.371 0.000
R22.0 Localised swelling, mass and lump, head
0.628 0.372 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.627 0.373 0.000
L03.8 Cellulitis of other sites
0.627 0.373 0.000
L85.9 Epidermal thickening, unspecified
0.627 0.373 0.000
J33.8 Other polyp of sinus
0.626 0.374 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.626 0.374 0.000
J93 Pneumothorax
0.625 0.375 0.000
O63.9 Long labour, unspecified
0.624 0.375 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.624 0.375 0.000
K35-K38 Diseases of appendix
0.624 0.376 0.000
H33.5 Other retinal detachments
0.623 0.377 0.000
M75.1 Rotator cuff syndrome
0.623 0.377 0.000
T90 Sequelae of injuries of head
0.623 0.377 0.000
M87 Osteonecrosis
0.623 0.377 0.000
L05 Pilonidal cyst
0.622 0.378 0.000
N60-N64 Disorders of breast
0.622 0.378 0.000
R07 Pain in throat and chest
0.622 0.378 0.000
F99-F99 Unspecified mental disorder
0.621 0.378 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.621 0.378 0.000
F80-F89 Disorders of psychological development
0.621 0.378 0.000
F70-F79 Mental retardation
0.621 0.378 0.000
F60-F69 Disorders of adult personality and behaviour
0.621 0.378 0.000
K86 Other diseases of pancreas
0.621 0.379 0.000
Z87.8 Personal history of other specified conditions
0.621 0.379 0.000
K70 Alcoholic liver disease
0.620 0.380 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.619 0.381 0.000
Z35 Supervision of high-risk pregnancy
0.619 0.381 0.000
T92 Sequelae of injuries of upper limb
0.618 0.382 0.000
R01 Cardiac murmurs and other cardiac sounds
0.616 0.384 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.616 0.384 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.616 0.384 0.000
H81.1 Benign paroxysmal vertigo
0.616 0.384 0.000
K83.0 Cholangitis
0.615 0.385 0.000
M06 Other rheumatoid arthritis
0.615 0.385 0.000
R47-R49 Symptoms and signs involving speech and voice
0.614 0.385 0.000
S00.8 Superficial injury of other parts of head
0.614 0.386 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.614 0.386 0.000
N27 Small kidney of unknown cause
0.614 0.386 0.000
N25 Disorders resulting from impaired renal tubular function
0.614 0.386 0.000
N26 Unspecified contracted kidney
0.614 0.386 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.614 0.386 0.000
S02 Fracture of skull and facial bones
0.614 0.386 0.000
C67.9 Bladder, unspecified
0.614 0.386 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.614 0.386 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.613 0.387 0.000
S20 Superficial injury of thorax
0.613 0.387 0.000
Z87.1 Personal history of diseases of the digestive system
0.613 0.387 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.613 0.387 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.613 0.387 0.000
L98.5 Mucinosis of skin
0.613 0.387 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.613 0.387 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.613 0.387 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.613 0.387 0.000
L98.1 Factitial dermatitis
0.613 0.387 0.000
Z90.8 Acquired absence of other organs
0.612 0.388 0.000
Z90.0 Acquired absence of part of head and neck
0.612 0.388 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.611 0.388 0.000
H60 Otitis externa
0.611 0.389 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.610 0.389 0.000
S48 Traumatic amputation of shoulder and upper arm
0.610 0.389 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.610 0.389 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.610 0.389 0.000
S44 Injury of nerves at shoulder and upper arm level
0.610 0.389 0.000
S41 Open wound of shoulder and upper arm
0.610 0.389 0.000
S40 Superficial injury of shoulder and upper arm
0.610 0.389 0.000
S47 Crushing injury of shoulder and upper arm
0.610 0.389 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.610 0.390 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.610 0.390 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.610 0.390 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.610 0.390 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.610 0.390 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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