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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117730468
log Bayes Factor = 15.6553
Chromosome 10   position 125,192,223  (GRCh37) Explore rs117730468 on Ensembl!
Variant rs117730468 is part of Cluster X0015

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.998 0.002 0.000
R50-R69 General symptoms and signs
0.997 0.003 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.996 0.004 0.000
D60-D64 Aplastic and other anaemias
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.996 0.004 0.000
D64 Other anaemias
0.995 0.005 0.000
Chapter XIV Diseases of the genitourinary system
0.995 0.005 0.000
D64.9 Anaemia, unspecified
0.994 0.006 0.000
M70-M79 Other soft tissue disorders
0.985 0.015 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.984 0.016 0.000
N17-N19 Renal failure
0.983 0.017 0.000
R42 Dizziness and giddiness
0.982 0.018 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.982 0.018 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.976 0.024 0.000
Chapter VI Diseases of the nervous system
0.973 0.027 0.000
R53 Malaise and fatigue
0.970 0.030 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.966 0.034 0.000
S00-S09 Injuries to the head
0.965 0.035 0.000
M79.8 Other specified soft tissue disorders
0.964 0.036 0.000
N18 Chronic renal failure
0.957 0.043 0.000
Chapter V Mental and behavioural disorders
0.957 0.043 0.000
Z50 Care involving use of rehabilitation procedures
0.950 0.050 0.000
N10-N16 Renal tubulo-interstitial diseases
0.942 0.058 0.000
R63 Symptoms and signs concerning food and fluid intake
0.939 0.061 0.000
Chapter XI Diseases of the digestive system
0.935 0.065 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.929 0.071 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.927 0.073 0.000
N18.9 Chronic renal failure, unspecified
0.927 0.073 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.927 0.073 0.000
S80-S89 Injuries to the knee and lower leg
0.926 0.074 0.000
G40-G47 Episodic and paroxysmal disorders
0.924 0.076 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.924 0.076 0.000
Z50.1 Other physical therapy
0.923 0.077 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.919 0.081 0.000
R51 Headache
0.919 0.081 0.000
M79.6 Pain in limb
0.916 0.084 0.000
M45-M49 Spondylopathies
0.914 0.086 0.000
M20-M25 Other joint disorders
0.908 0.092 0.000
Chapter I Certain infectious and parasitic diseases
0.903 0.097 0.000
N00-N08 Glomerular diseases
0.902 0.098 0.000
G47 Sleep disorders
0.901 0.099 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.896 0.104 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.893 0.107 0.000
K50-K52 Noninfective enteritis and colitis
0.891 0.109 0.000
Chapter XX External causes of morbidity and mortality
0.887 0.113 0.000
R13 Dysphagia
0.879 0.121 0.000
Z53.9 Procedure not carried out, unspecified reason
0.878 0.122 0.000
T81 Complications of procedures, not elsewhere classified
0.876 0.124 0.000
Chapter II Neoplasms
0.873 0.127 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.872 0.128 0.000
K08 Other disorders of teeth and supporting structures
0.871 0.129 0.000
R63.0 Anorexia
0.869 0.131 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.861 0.139 0.000
N60-N64 Disorders of breast
0.859 0.141 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.859 0.141 0.000
K52 Other non-infective gastro-enteritis and colitis
0.857 0.143 0.000
N19 Unspecified renal failure
0.856 0.144 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.856 0.144 0.000
N13 Obstructive and reflux uropathy
0.855 0.145 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.855 0.145 0.000
R11 Nausea and vomiting
0.854 0.146 0.000
S09 Other and unspecified injuries of head
0.853 0.147 0.000
Chapter VIII Diseases of the ear and mastoid process
0.853 0.147 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.852 0.148 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.851 0.149 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.850 0.150 0.000
G47.3 Sleep apnoea
0.844 0.156 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.844 0.156 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.843 0.157 0.000
R10 Abdominal and pelvic pain
0.842 0.158 0.000
Z51 Other medical care
0.839 0.161 0.000
R10.4 Other and unspecified abdominal pain
0.830 0.170 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.830 0.170 0.000
R26 Abnormalities of gait and mobility
0.828 0.172 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.826 0.174 0.000
R55 Syncope and collapse
0.826 0.174 0.000
C15-C26 Malignant neoplasms of digestive organs
0.825 0.175 0.000
R14 Flatulence and related conditions
0.823 0.177 0.000
R54 Senility
0.820 0.180 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.818 0.182 0.000
K08.3 Retained dental root
0.816 0.184 0.000
R40 Somnolence, stupor and coma
0.815 0.185 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.815 0.185 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.813 0.187 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.812 0.188 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.810 0.190 0.000
N18.4 Chronic kidney disease, stage 4
0.807 0.193 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.807 0.193 0.000
M40-M43 Deforming dorsopathies
0.806 0.194 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.806 0.194 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.805 0.195 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.803 0.197 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.800 0.200 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.799 0.201 0.000
F30-F39 Mood [affective] disorders
0.798 0.202 0.000
K07 Dentofacial anomalies [including malocclusion]
0.798 0.202 0.000
W00-W19 Falls
0.798 0.202 0.000
T86 Failure and rejection of transplanted organs and tissues
0.796 0.204 0.000
S20-S29 Injuries to the thorax
0.796 0.204 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.796 0.204 0.000
K02 Dental caries
0.796 0.204 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.795 0.204 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.795 0.205 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.795 0.205 0.000
S01 Open wound of head
0.794 0.206 0.000
D50-D53 Nutritional anaemias
0.793 0.207 0.000
D80-D89 Certain disorders involving the immune mechanism
0.793 0.207 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.792 0.208 0.000
S50-S59 Injuries to the elbow and forearm
0.790 0.210 0.000
K04 Diseases of pulp and periapical tissues
0.789 0.211 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.788 0.212 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.786 0.213 0.000
S00 Superficial injury of head
0.786 0.214 0.000
R45 Symptoms and signs involving emotional state
0.785 0.215 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.784 0.216 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.783 0.217 0.000
Z51.5 Palliative care
0.782 0.218 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.782 0.218 0.000
S05 Injury of eye and orbit
0.781 0.219 0.000
R63.4 Abnormal weight loss
0.779 0.221 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.779 0.221 0.000
Z50.5 Speech therapy
0.779 0.221 0.000
M22 Disorders of patella
0.778 0.222 0.000
N17 Acute renal failure
0.778 0.222 0.000
N18.5 Chronic kidney disease, stage 5
0.778 0.222 0.000
Z48 Other surgical follow-up care
0.777 0.223 0.000
S90-S99 Injuries to the ankle and foot
0.777 0.223 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.777 0.223 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.776 0.224 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.776 0.224 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.775 0.225 0.000
S80 Superficial injury of lower leg
0.774 0.225 0.000
S09.9 Unspecified injury of head
0.773 0.227 0.000
Z54 Convalescence
0.773 0.227 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.772 0.228 0.000
M05-M14 Inflammatory polyarthropathies
0.771 0.229 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.768 0.232 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.767 0.233 0.000
F60-F69 Disorders of adult personality and behaviour
0.766 0.234 0.000
Chapter XXII Codes for special purposes
0.765 0.234 0.000
M79.7 Fibromyalgia
0.764 0.236 0.000
R41.0 Disorientation, unspecified
0.764 0.236 0.000
G47.9 Sleep disorder, unspecified
0.762 0.238 0.000
M48 Other spondylopathies
0.762 0.238 0.000
N04 Nephrotic syndrome
0.760 0.240 0.000
G47.8 Other sleep disorders
0.759 0.241 0.000
B35-B49 Mycoses
0.756 0.244 0.000
M35 Other systemic involvement of connective tissue
0.755 0.245 0.000
K90-K93 Other diseases of the digestive system
0.755 0.245 0.000
A30-A49 Other bacterial diseases
0.754 0.246 0.000
S06 Intracranial injury
0.750 0.250 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.749 0.251 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.747 0.253 0.000
Z51.2 Other chemotherapy
0.745 0.255 0.000
M65-M68 Disorders of synovium and tendon
0.745 0.255 0.000
G70-G73 Diseases of myoneural junction and muscle
0.745 0.255 0.000
Z60 Problems related to social environment
0.744 0.256 0.000
F80-F89 Disorders of psychological development
0.744 0.256 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.744 0.256 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.743 0.257 0.000
L20-L30 Dermatitis and eczema
0.743 0.257 0.000
S89 Other and unspecified injuries of lower leg
0.742 0.258 0.000
F17.1 Harmful use
0.742 0.258 0.000
M47 Spondylosis
0.742 0.258 0.000
M23 Internal derangement of knee
0.742 0.258 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.742 0.258 0.000
R21 Rash and other nonspecific skin eruption
0.742 0.258 0.000
M79.0 Rheumatism, unspecified
0.741 0.259 0.000
Z73 Problems related to life-management difficulty
0.738 0.262 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.737 0.263 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.737 0.263 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.735 0.265 0.000
R52 Pain, not elsewhere classified
0.734 0.266 0.000
R50 Fever of unknown origin
0.733 0.267 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.732 0.268 0.000
C18 Malignant neoplasm of colon
0.731 0.269 0.000
N10 Acute tubulo-interstitial nephritis
0.731 0.269 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.730 0.270 0.000
T66-T78 Other and unspecified effects of external causes
0.730 0.270 0.000
M79.66 Pain in limb (Lower leg)
0.729 0.271 0.000
M25 Other joint disorders, not elsewhere classified
0.728 0.272 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.728 0.272 0.000
M71 Other bursopathies
0.728 0.272 0.000
N05 Unspecified nephritic syndrome
0.728 0.272 0.000
M80-M85 Disorders of bone density and structure
0.727 0.273 0.000
M45 Ankylosing spondylitis
0.726 0.274 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.726 0.274 0.000
K70-K77 Diseases of liver
0.725 0.275 0.000
F32 Depressive episode
0.724 0.275 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.724 0.276 0.000
N70 Salpingitis and oophoritis
0.723 0.277 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.722 0.278 0.000
T79-T79 Certain early complications of trauma
0.721 0.279 0.000
Z50.8 Care involving use of rehabilitation procedures
0.720 0.280 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.719 0.281 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.719 0.281 0.000
N99-N99 Other disorders of the genitourinary system
0.718 0.282 0.000
G20-G26 Extrapyramidal and movement disorders
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
K50 Crohn's disease [regional enteritis]
0.716 0.284 0.000
R59 Enlarged lymph nodes
0.716 0.284 0.000
M91-M94 Chondropathies
0.715 0.284 0.000
M60-M63 Disorders of muscles
0.715 0.284 0.000
M00-M03 Infectious arthropathies
0.715 0.284 0.000
D55-D59 Haemolytic anaemias
0.715 0.284 0.000
S81 Open wound of lower leg
0.715 0.285 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.715 0.285 0.000
R68 Other general symptoms and signs
0.715 0.285 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.715 0.285 0.000
R62 Lack of expected normal physiological development
0.715 0.285 0.000
R57 Shock, not elsewhere classified
0.715 0.285 0.000
R64 Cachexia
0.715 0.285 0.000
R58 Haemorrhage, not elsewhere classified
0.715 0.285 0.000
M86-M90 Other osteopathies
0.715 0.285 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.714 0.285 0.000
R46 Symptoms and signs involving appearance and behaviour
0.714 0.286 0.000
R43 Disturbances of smell and taste
0.714 0.286 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.714 0.286 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.714 0.286 0.000
D62 Acute posthaemorrhagic anaemia
0.714 0.286 0.000
D64.8 Other specified anaemias
0.713 0.287 0.000
D64.4 Congenital dyserythropoietic anaemia
0.713 0.287 0.000
D64.3 Other sideroblastic anaemias
0.713 0.287 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.713 0.287 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.713 0.287 0.000
D64.0 Hereditary sideroblastic anaemia
0.713 0.287 0.000
M79.60 Pain in limb (Multiple sites)
0.711 0.289 0.000
R23 Other skin changes
0.711 0.289 0.000
M79.63 Pain in limb (Forearm)
0.707 0.293 0.000
M77 Other enthesopathies
0.706 0.293 0.000
M76 Enthesopathies of lower limb, excluding foot
0.706 0.293 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.706 0.293 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.706 0.293 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.706 0.294 0.000
T87 Complications peculiar to reattachment and amputation
0.705 0.295 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.705 0.295 0.000
R25 Abnormal involuntary movements
0.705 0.295 0.000
K04.8 Radicular cyst
0.705 0.295 0.000
K14 Diseases of tongue
0.704 0.296 0.000
B25-B34 Other viral diseases
0.704 0.296 0.000
M79.9 Soft tissue disorder, unspecified
0.704 0.296 0.000
M79.5 Residual foreign body in soft tissue
0.704 0.296 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.704 0.296 0.000
M79.3 Panniculitis, unspecified
0.704 0.296 0.000
M79.2 Neuralgia and neuritis, unspecified
0.704 0.296 0.000
M79.1 Myalgia
0.704 0.296 0.000
K02.9 Dental caries, unspecified
0.704 0.296 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.700 0.300 0.000
Z52 Donors of organs and tissues
0.700 0.300 0.000
Z49 Care involving dialysis
0.700 0.300 0.000
Z44 Fitting and adjustment of external prosthetic device
0.700 0.300 0.000
H60-H62 Diseases of external ear
0.700 0.300 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.698 0.301 0.000
M46 Other inflammatory spondylopathies
0.698 0.302 0.000
R18 Ascites
0.698 0.302 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.697 0.302 0.000
N61 Inflammatory disorders of breast
0.697 0.303 0.000
T17 Foreign body in respiratory tract
0.696 0.304 0.000
N02 Recurrent and persistent haematuria
0.695 0.305 0.000
R60 Oedema, not elsewhere classified
0.695 0.305 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.695 0.305 0.000
H90-H95 Other disorders of ear
0.694 0.306 0.000
W19 Unspecified fall
0.694 0.306 0.000
M79.62 Pain in limb (Upper arm)
0.693 0.306 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.693 0.307 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.693 0.307 0.000
S08 Traumatic amputation of part of head
0.692 0.308 0.000
S07 Crushing injury of head
0.692 0.308 0.000
S04 Injury of cranial nerves
0.692 0.308 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.692 0.308 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.691 0.309 0.000
M79.88 Other specified soft tissue disorders (Other)
0.691 0.309 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.691 0.309 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.691 0.309 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.691 0.309 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.691 0.309 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.691 0.309 0.000
N13.3 Other and unspecified hydronephrosis
0.691 0.309 0.000
N73 Other female pelvic inflammatory diseases
0.687 0.313 0.000
G51 Facial nerve disorders
0.687 0.313 0.000
N18.8 Other chronic renal failure
0.686 0.314 0.000
N18.2 Chronic kidney disease, stage 2
0.686 0.314 0.000
N18.1 Chronic kidney disease, stage 1
0.686 0.314 0.000
F99-F99 Unspecified mental disorder
0.686 0.314 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.686 0.314 0.000
F70-F79 Mental retardation
0.686 0.314 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.686 0.314 0.000
R19.5 Other fecal abnormalities
0.686 0.314 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.686 0.314 0.000
K07.6 Temporomandibular joint disorders
0.686 0.314 0.000
Z51.3 Blood transfusion without reported diagnosis
0.685 0.315 0.000
K52.1 Toxic gastro-enteritis and colitis
0.684 0.316 0.000
S02 Fracture of skull and facial bones
0.683 0.316 0.000
Z04 Examination and observation for other reasons
0.682 0.318 0.000
Z50.6 Orthoptic training
0.681 0.319 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.681 0.319 0.000
Z50.3 Drug rehabilitation
0.681 0.319 0.000
Z50.2 Alcohol rehabilitation
0.681 0.319 0.000
M35.3 Polymyalgia rheumatica
0.681 0.319 0.000
Z29 Need for other prophylactic measures
0.680 0.320 0.000
B95-B98 Bacterial, viral and other infectious agents
0.679 0.321 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.679 0.321 0.000
N62 Hypertrophy of breast
0.676 0.324 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.675 0.324 0.000
N15 Other renal tubulo-interstitial diseases
0.675 0.324 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.675 0.324 0.000
N11 Chronic tubulo-interstitial nephritis
0.675 0.324 0.000
N03 Chronic nephritic syndrome
0.675 0.325 0.000
K12 Stomatitis and related lesions
0.675 0.325 0.000
Z40 Prophylactic surgery
0.674 0.325 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.674 0.326 0.000
R41.3 Other amnesia
0.673 0.326 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.673 0.327 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.673 0.327 0.000
R63.5 Abnormal weight gain
0.673 0.327 0.000
R63.3 Feeding difficulties and mismanagement
0.673 0.327 0.000
R63.2 Polyphagia
0.673 0.327 0.000
R63.1 Polydipsia
0.673 0.327 0.000
R56 Convulsions, not elsewhere classified
0.673 0.327 0.000
K01 Embedded and impacted teeth
0.672 0.328 0.000
F32.9 Depressive episode, unspecified
0.672 0.328 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.671 0.329 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.671 0.329 0.000
S01.0 Open wound of scalp
0.670 0.330 0.000
Z02 Examination and encounter for administrative purposes
0.669 0.331 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.669 0.331 0.000
M79.69 Pain in limb (Site unspecified)
0.669 0.331 0.000
M43 Other deforming dorsopathies
0.669 0.331 0.000
M21 Other acquired deformities of limbs
0.669 0.331 0.000
S80.9 Superficial injury of lower leg, unspecified
0.666 0.334 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.666 0.334 0.000
D61 Other aplastic anaemias
0.666 0.334 0.000
M24 Other specific joint derangements
0.666 0.334 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.666 0.334 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.666 0.334 0.000
Z60.2 Living alone
0.665 0.335 0.000
Z10 Routine general health check-up of defined subpopulation
0.664 0.336 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.664 0.336 0.000
G30-G32 Other degenerative diseases of the nervous system
0.664 0.336 0.000
S88 Traumatic amputation of lower leg
0.664 0.336 0.000
S87 Crushing injury of lower leg
0.664 0.336 0.000
S86 Injury of muscle and tendon at lower leg level
0.664 0.336 0.000
S85 Injury of blood vessels at lower leg level
0.664 0.336 0.000
S84 Injury of nerves at lower leg level
0.664 0.336 0.000
R40.0 Somnolence
0.664 0.336 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.663 0.337 0.000
G44 Other headache syndromes
0.663 0.337 0.000
G41 Status epilepticus
0.663 0.337 0.000
K10 Other diseases of jaws
0.662 0.338 0.000
K09 Cysts of oral region, not elsewhere classified
0.662 0.338 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.662 0.338 0.000
K03 Other diseases of hard tissues of teeth
0.662 0.338 0.000
K00 Disorders of tooth development and eruption
0.662 0.338 0.000
T86.1 Kidney transplant failure and rejection
0.662 0.338 0.000
M22.8 Other disorders of patella
0.662 0.338 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.662 0.338 0.000
D50 Iron deficiency anaemia
0.662 0.338 0.000
R80 Isolated proteinuria
0.661 0.339 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.661 0.339 0.000
S40-S49 Injuries to the shoulder and upper arm
0.661 0.339 0.000
Q60-Q64 Congenital malformations of the urinary system
0.661 0.339 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.659 0.341 0.000
R27 Other lack of coordination
0.659 0.341 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.659 0.341 0.000
N04.9 Unspecified
0.658 0.342 0.000
A00-A09 Intestinal infectious diseases
0.657 0.343 0.000
T88.5 Other complications of anaesthesia
0.657 0.343 0.000
M79.68 Pain in limb (Other)
0.657 0.343 0.000
M79.64 Pain in limb (Hand)
0.657 0.343 0.000
M79.61 Pain in limb (Shoulder region)
0.657 0.343 0.000
Z48.0 Attention to surgical dressings and sutures
0.657 0.343 0.000
Chapter IX Diseases of the circulatory system
0.655 0.345 0.000
M49 Spondylopathies in diseases classified elsewhere
0.655 0.345 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.655 0.345 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.654 0.345 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.654 0.346 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.654 0.346 0.000
M48.0 Spinal stenosis
0.653 0.347 0.000
S20 Superficial injury of thorax
0.653 0.347 0.000
S70-S79 Injuries to the hip and thigh
0.652 0.347 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.651 0.349 0.000
M34 Systemic sclerosis
0.651 0.349 0.000
M33 Dermatopolymyositis
0.651 0.349 0.000
M32 Systemic lupus erythematosus
0.651 0.349 0.000
M30 Polyarteritis nodosa and related conditions
0.651 0.349 0.000
B37 Candidiasis
0.651 0.349 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.650 0.350 0.000
N13.4 Hydroureter
0.649 0.351 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.649 0.351 0.000
B15-B19 Viral hepatitis
0.649 0.351 0.000
G12 Spinal muscular atrophy and related syndromes
0.649 0.351 0.000
R26.3 Immobility
0.648 0.352 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.647 0.353 0.000
B99-B99 Other infectious diseases
0.647 0.353 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.647 0.353 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.647 0.353 0.000
B65-B83 Helminthiases
0.647 0.353 0.000
B50-B64 Protozoal diseases
0.647 0.353 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.647 0.353 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.647 0.353 0.000
A80-A89 Viral infections of the central nervous system
0.647 0.353 0.000
A75-A79 Rickettsioses
0.647 0.353 0.000
A70-A74 Other diseases caused by chlamydiae
0.647 0.353 0.000
A65-A69 Other spirochaetal diseases
0.647 0.353 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.647 0.353 0.000
A20-A28 Certain zoonotic bacterial diseases
0.647 0.353 0.000
A15-A19 Tuberculosis
0.647 0.353 0.000
D68 Other coagulation defects
0.647 0.353 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.647 0.353 0.000
N06 Isolated proteinuria with specified morphological lesion
0.647 0.353 0.000
N01 Rapidly progressive nephritic syndrome
0.647 0.353 0.000
N00 Acute nephritic syndrome
0.647 0.353 0.000
Z74 Problems related to care-provider dependency
0.646 0.354 0.000
N64 Other disorders of breast
0.646 0.354 0.000
D86 Sarcoidosis
0.646 0.354 0.000
G47.4 Narcolepsy and cataplexy
0.646 0.354 0.000
G47.2 Disorders of the sleep-wake schedule
0.646 0.354 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.646 0.354 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.646 0.354 0.000
R50.0 Fever with chills
0.646 0.354 0.000
W17 Other fall from one level to another
0.646 0.354 0.000
Z53.8 Procedure not carried out for other reasons
0.646 0.354 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.645 0.354 0.000
K05 Gingivitis and periodontal diseases
0.645 0.354 0.000
Z50.0 Cardiac rehabilitation
0.645 0.355 0.000
L85 Other epidermal thickening
0.645 0.355 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.643 0.357 0.000
C60-C63 Malignant neoplasms of male genital organs
0.643 0.357 0.000
L10-L14 Bullous disorders
0.642 0.358 0.000
M31 Other necrotising vasculopathies
0.642 0.358 0.000
N60 Benign mammary dysplasia
0.641 0.359 0.000
Z51.8 Other specified medical care
0.640 0.360 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.638 0.361 0.000
S82 Fracture of lower leg, including ankle
0.638 0.361 0.000
Z63 Other problems related to primary support group, including family circumstances
0.638 0.362 0.000
M23.3 Other meniscus derangements
0.638 0.362 0.000
A49 Bacterial infection of unspecified site
0.638 0.362 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.636 0.364 0.000
Y35-Y36 Legal intervention and operations of war
0.636 0.364 0.000
Y10-Y34 Event of undetermined intent
0.636 0.364 0.000
Y00-Y09 Assault
0.636 0.364 0.000
X85-X99 Assault
0.636 0.364 0.000
X60-X84 Intentional self-harm
0.636 0.364 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.636 0.364 0.000
X50-X57 Overexertion, travel and privation
0.636 0.364 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.636 0.364 0.000
X30-X39 Exposure to forces of nature
0.636 0.364 0.000
X20-X29 Contact with venomous animals and plants
0.636 0.364 0.000
X10-X19 Contact with heat and hot substances
0.636 0.364 0.000
X00-X09 Exposure to smoke, fire and flames
0.636 0.364 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.636 0.364 0.000
W75-W84 Other accidental threats to breathing
0.636 0.364 0.000
W65-W74 Accidental drowning and submersion
0.636 0.364 0.000
W50-W64 Exposure to animate mechanical forces
0.636 0.364 0.000
V98-V99 Other and unspecified transport accidents
0.636 0.364 0.000
V95-V97 Air and space transport accidents
0.636 0.364 0.000
V90-V94 Water transport accidents
0.636 0.364 0.000
V80-V89 Other land transport accidents
0.636 0.364 0.000
V70-V79 Bus occupant injured in transport accident
0.636 0.364 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.636 0.364 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.636 0.364 0.000
V40-V49 Car occupant injured in transport accident
0.636 0.364 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.636 0.364 0.000
V20-V29 Motorcycle rider injured in transport accident
0.636 0.364 0.000
V01-V09 Pedestrian injured in transport accident
0.636 0.364 0.000
N70.1 Chronic salpingitis and oophoritis
0.636 0.364 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.636 0.364 0.000
L60-L75 Disorders of skin appendages
0.634 0.366 0.000
R45.1 Restlessness and agitation
0.633 0.367 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.633 0.367 0.000
K11 Diseases of salivary glands
0.633 0.367 0.000
C18.7 Sigmoid colon
0.633 0.367 0.000
L90 Atrophic disorders of skin
0.632 0.368 0.000
N17.9 Acute renal failure, unspecified
0.632 0.368 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.632 0.368 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.631 0.369 0.000
M47.9 Spondylosis, unspecified
0.630 0.370 0.000
F60 Specific personality disorders
0.630 0.370 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.630 0.370 0.000
T81.9 Unspecified complication of procedure
0.628 0.372 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.628 0.372 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.628 0.372 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.628 0.372 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.628 0.372 0.000
L82 Seborrhoeic keratosis
0.628 0.372 0.000
K35-K38 Diseases of appendix
0.628 0.372 0.000
Z54.0 Convalescence following surgery
0.627 0.373 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.626 0.374 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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