TreeWAS – Variant ID: rs117744154

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter XI Diseases of the digestive system	0.999	0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001
K20-K31 Diseases of oesophagus, stomach and duodenum	0.997	0.003
M50-M54 Other dorsopathies	0.991	0.009
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.991	0.009
Chapter XII Diseases of the skin and subcutaneous tissue	0.990	0.010
I60-I69 Cerebrovascular diseases	0.989	0.011
K20 Oesophagitis	0.988	0.012
M45-M49 Spondylopathies	0.982	0.018
Chapter XIV Diseases of the genitourinary system	0.980	0.020
Chapter XXI Factors influencing health status and contact with health services	0.979	0.021
Chapter II Neoplasms	0.978	0.022
I30-I52 Other forms of heart disease	0.975	0.025
K70-K77 Diseases of liver	0.973	0.027
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.973	0.027
I35 Nonrheumatic aortic valve disorders	0.970	0.030
Z95 Presence of cardiac and vascular implants and grafts	0.970	0.030
M54 Dorsalgia	0.968	0.032
Z92 Personal history of medical treatment	0.960	0.040
I70-I79 Diseases of arteries, arterioles and capillaries	0.960	0.040
I69 Sequelae of cerebrovascular disease	0.956	0.044
I95-I99 Other and unspecified disorders of the circulatory system	0.948	0.052
Z95.2 Presence of prosthetic heart valve	0.946	0.054
K50-K52 Noninfective enteritis and colitis	0.945	0.055
Chapter I Certain infectious and parasitic diseases	0.944	0.056
M05-M14 Inflammatory polyarthropathies	0.943	0.057
K31 Other diseases of stomach and duodenum	0.942	0.058
M51 Other intervertebral disk disorders	0.938	0.062
D00-D09 In situ neoplasms	0.937	0.063
N20-N23 Urolithiasis	0.934	0.066
M47 Spondylosis	0.933	0.067
N17-N19 Renal failure	0.930	0.070
K26 Duodenal ulcer	0.927	0.073
D10-D36 Benign neoplasms	0.926	0.074
Z95.4 Presence of other heart-valve replacement	0.925	0.075
D37-D48 Neoplasms of uncertain or unknown behaviour	0.924	0.076
I63 Cerebral infarction	0.924	0.076
K31.7 Polyp of stomach and duodenum	0.921	0.079
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.920	0.080
Z92.1 Personal history of long-term (current) use of anticoagulants	0.919	0.081
S80-S89 Injuries to the knee and lower leg	0.917	0.083
L40-L45 Papulosquamous disorders	0.913	0.087
M48 Other spondylopathies	0.913	0.087
N25-N29 Other disorders of kidney and ureter	0.912	0.088
Chapter IV Endocrine, nutritional and metabolic diseases	0.911	0.089
I35.1 Aortic (valve) insufficiency	0.910	0.090
N18 Chronic renal failure	0.908	0.092
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.907	0.093
Z70-Z76 Persons encountering health services in other circumstances	0.905	0.095
Z98 Other postsurgical states	0.905	0.095
M51.2 Other specified intervertebral disk displacement	0.901	0.099
L80-L99 Other disorders of the skin and subcutaneous tissue	0.901	0.099
B95-B98 Bacterial, viral and other infectious agents	0.898	0.102
L00-L08 Infections of the skin and subcutaneous tissue	0.897	0.103
I63.9 Cerebral infarction, unspecified	0.897	0.103
Z92.3 Personal history of irradiation	0.897	0.103
M10 Gout	0.897	0.103
M54.1 Radiculopathy	0.885	0.115
K51 Ulcerative colitis	0.885	0.115
M54.2 Cervicalgia	0.885	0.115
I35.2 Aortic (valve) stenosis with insufficiency	0.882	0.118
S60-S69 Injuries to the wrist and hand	0.880	0.120
K22 Other diseases of oesophagus	0.878	0.122
I95 Hypotension	0.877	0.123
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.875	0.125
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.874	0.125
K76 Other diseases of liver	0.873	0.127
Z72 Problems related to lifestyle	0.868	0.132
N18.3 Chronic kidney disease, stage 3	0.868	0.132
N23 Unspecified renal colic	0.866	0.134
L40 Psoriasis	0.866	0.134
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.864	0.136
M10.9 Gout, unspecified	0.864	0.136
I35.0 Aortic (valve) stenosis	0.863	0.137
N28 Other disorders of kidney and ureter, not elsewhere classified	0.863	0.137
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.858	0.142
K74 Fibrosis and cirrhosis of liver	0.858	0.142
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.857	0.143
N70-N77 Inflammatory diseases of female pelvic organs	0.855	0.145
Z98.0 Intestinal bypass and anastomosis status	0.854	0.146
D06 Carcinoma in situ of cervix uteri	0.853	0.147
Z72.1 Alcohol use	0.850	0.150
M91-M94 Chondropathies	0.849	0.151
Chapter XV Pregnancy, childbirth and the puerperium	0.847	0.153
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.847	0.153
M48.0 Spinal stenosis	0.844	0.156
K22.7 Barrett's oesophagus	0.844	0.156
Z92.6 Personal history of chemotherapy for neoplastic disease	0.842	0.158
L02 Cutaneous abscess, furuncle and carbuncle	0.839	0.161
K26.7 Chronic without haemorrhage or perforation	0.834	0.166
I35.8 Other aortic valve disorders	0.833	0.167
I45 Other conduction disorders	0.833	0.167
I95.1 Orthostatic hypotension	0.833	0.167
N28.1 Cyst of kidney, acquired	0.831	0.169
Z95.8 Presence of other cardiac and vascular implants and grafts	0.831	0.169
N00-N08 Glomerular diseases	0.828	0.172
M10.99 Gout, unspecified (Site unspecified)	0.828	0.172
Z88.6 Personal history of allergy to analgesic agent	0.828	0.172
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.828	0.172
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.826	0.173
M47.9 Spondylosis, unspecified	0.826	0.174
M54.16 Radiculopathy (Lumbar region)	0.825	0.175
K75 Other inflammatory liver diseases	0.823	0.177
L90 Atrophic disorders of skin	0.823	0.177
M54.9 Dorsalgia, unspecified	0.821	0.179
D32 Benign neoplasm of meninges	0.821	0.179
S20-S29 Injuries to the thorax	0.819	0.181
S00-S09 Injuries to the head	0.818	0.182
I50 Heart failure	0.816	0.184
I33 Acute and subacute endocarditis	0.814	0.186
D12.8 Rectum	0.814	0.186
Chapter V Mental and behavioural disorders	0.813	0.187
I71 Aortic aneurysm and dissection	0.806	0.194
Z97 Presence of other devices	0.804	0.196
M47.8 Other spondylosis	0.804	0.196
M48.06 Spinal stenosis (Lumbar region)	0.804	0.196
S10-S19 Injuries to the neck	0.802	0.197
S40-S49 Injuries to the shoulder and upper arm	0.801	0.199
D25 Leiomyoma of uterus	0.799	0.201
K26.4 Chronic or unspecified with haemorrhage	0.797	0.203
M54.22 Cervicalgia (Cervical region)	0.796	0.204
A30-A49 Other bacterial diseases	0.795	0.205
S70-S79 Injuries to the hip and thigh	0.794	0.206
D06.9 Cervix, unspecified	0.793	0.207
N18.9 Chronic renal failure, unspecified	0.792	0.208
K50 Crohn's disease [regional enteritis]	0.789	0.211
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.787	0.213
L40.9 Psoriasis, unspecified	0.787	0.213
K90-K93 Other diseases of the digestive system	0.785	0.215
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.784	0.216
I05-I09 Chronic rheumatic heart diseases	0.784	0.216
I10-I15 Hypertensive diseases	0.783	0.217
I74 Arterial embolism and thrombosis	0.782	0.218
E10-E14 Diabetes mellitus	0.782	0.218
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.780	0.220
I99 Other and unspecified disorders of circulatory system	0.779	0.221
B15-B19 Viral hepatitis	0.779	0.221
D34 Benign neoplasm of thyroid gland	0.779	0.221
D70-D77 Other diseases of blood and blood-forming organs	0.778	0.222
K51.9 Ulcerative colitis, unspecified	0.778	0.222
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.776	0.224
D24 Benign neoplasm of breast	0.775	0.225
K76.8 Other specified diseases of liver	0.774	0.226
S81 Open wound of lower leg	0.773	0.227
I69.3 Sequelae of cerebral infarction	0.772	0.228
I72 Other aneurysm	0.771	0.229
L89 Decubitus ulcer	0.769	0.231
O20-O29 Other maternal disorders predominantly related to pregnancy	0.767	0.233
I77 Other disorders of arteries and arterioles	0.766	0.234
S64 Injury of nerves at wrist and hand level	0.766	0.234
Chapter VII Diseases of the eye and adnexa	0.765	0.235
Chapter XX External causes of morbidity and mortality	0.765	0.235
T92 Sequelae of injuries of upper limb	0.763	0.237
Chapter XXII Codes for special purposes	0.762	0.238
L40.5 Arthropathic psoriasis	0.761	0.239
D25.9 Leiomyoma of uterus, unspecified	0.761	0.239
N70 Salpingitis and oophoritis	0.761	0.239
N21 Calculus of lower urinary tract	0.760	0.240
M60-M63 Disorders of muscles	0.760	0.240
S83.2 Tear of meniscus, current	0.758	0.242
I50.9 Heart failure, unspecified	0.757	0.243
E70-E90 Metabolic disorders	0.756	0.244
I67 Other cerebrovascular diseases	0.755	0.245
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.754	0.246
Z89 Acquired absence of limb	0.753	0.247
M47.2 Other spondylosis with radiculopathy	0.753	0.247
D46 Myelodysplastic syndromes	0.753	0.247
I78 Diseases of capillaries	0.753	0.247
M05 Seropositive rheumatoid arthritis	0.751	0.249
I73 Other peripheral vascular diseases	0.751	0.249
D05 Carcinoma in situ of breast	0.750	0.250
L90.5 Scar conditions and fibrosis of skin	0.750	0.250
I36 Nonrheumatic tricuspid valve disorders	0.749	0.251
M07 Psoriatic and enteropathic arthropathies	0.749	0.251
D09 Carcinoma in situ of other and unspecified sites	0.749	0.251
S80 Superficial injury of lower leg	0.749	0.251
C15-C26 Malignant neoplasms of digestive organs	0.748	0.252
L94 Other localised connective tissue disorders	0.744	0.256
I61 Intracerebral haemorrhage	0.743	0.257
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.743	0.257
Z88.2 Personal history of allergy to sulphonamides	0.740	0.260
K26.3 Acute without haemorrhage or perforation	0.739	0.261
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.739	0.261
N20 Calculus of kidney and ureter	0.739	0.261
E87 Other disorders of fluid, electrolyte and acid-base balance	0.737	0.263
I45.6 Preexcitation syndrome	0.736	0.264
M54.5 Low back pain	0.736	0.264
M46 Other inflammatory spondylopathies	0.734	0.266
L60-L75 Disorders of skin appendages	0.734	0.266
E20-E35 Disorders of other endocrine glands	0.734	0.266
I30 Acute pericarditis	0.734	0.266
D35 Benign neoplasm of other and unspecified endocrine glands	0.733	0.266
Q60-Q64 Congenital malformations of the urinary system	0.733	0.267
Z92.0 Personal history of contraception	0.733	0.267
L81 Other disorders of pigmentation	0.733	0.267
N02 Recurrent and persistent haematuria	0.732	0.268
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.732	0.268
I62 Other nontraumatic intracranial haemorrhage	0.730	0.269
S90-S99 Injuries to the ankle and foot	0.730	0.270
K40-K46 Hernia	0.730	0.270
K72 Hepatic failure, not elsewhere classified	0.729	0.271
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.728	0.272
K51.8 Other ulcerative colitis	0.728	0.272
M47.86 Other spondylosis (Lumbar region)	0.727	0.273
M48.5 Collapsed vertebra, not elsewhere classified	0.727	0.273
D27 Benign neoplasm of ovary	0.726	0.274
D04 Carcinoma in situ of skin	0.725	0.275
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.725	0.275
Z95.0 Presence of cardiac pacemaker	0.725	0.275
D12.4 Descending colon	0.724	0.276
I98 Other disorders of circulatory system in diseases classified elsewhere	0.722	0.277
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.722	0.278
A41 Other septicaemia	0.722	0.278
N99-N99 Other disorders of the genitourinary system	0.722	0.278
D32.0 Cerebral meninges	0.722	0.278
M54.4 Lumbago with sciatica	0.721	0.279
K26.5 Chronic or unspecified with perforation	0.721	0.279
K70 Alcoholic liver disease	0.720	0.280
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.720	0.280
B97 Viral agents as the cause of diseases classified to other chapters	0.720	0.280
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.720	0.280
N10-N16 Renal tubulo-interstitial diseases	0.719	0.281
K65-K67 Diseases of peritoneum	0.718	0.282
S69 Other and unspecified injuries of wrist and hand	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
I64 Stroke, not specified as haemorrhage or infarction	0.717	0.283
M00-M03 Infectious arthropathies	0.716	0.283
E50-E64 Other nutritional deficiencies	0.716	0.284
M54.29 Cervicalgia-Site unspe	0.715	0.285
K28 Gastrojejunal ulcer	0.715	0.285
K23 Disorders of oesophagus in diseases classified elsewhere	0.715	0.285
L50-L54 Urticaria and erythema	0.714	0.285
T66-T78 Other and unspecified effects of external causes	0.714	0.286
I35.9 Aortic valve disorder, unspecified	0.714	0.286
K51.4 Pseudopolyposis of colon	0.713	0.287
N17 Acute renal failure	0.713	0.287
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.712	0.288
Z98.8 Other specified postsurgical states	0.712	0.288
N18.2 Chronic kidney disease, stage 2	0.711	0.289
M53 Other dorsopathies, not elsewhere classified	0.711	0.289
D11 Benign neoplasm of major salivary glands	0.711	0.289
I44 Atrioventricular and left bundle-branch block	0.710	0.290
T79-T79 Certain early complications of trauma	0.710	0.290
T33-T35 Frostbite	0.710	0.290
T26-T28 Burns and corrosions confined to eye and internal organs	0.710	0.290
T20-T25 Burns and corrosions of external body surface, specified by site	0.710	0.290
T15-T19 Effects of foreign body entering through natural orifice	0.710	0.290
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.710	0.290
T00-T07 Injuries involving multiple body regions	0.710	0.290
Z83 Family history of other specific disorders	0.710	0.290
L10-L14 Bullous disorders	0.710	0.290
D18 Haemangioma and lymphangioma, any site	0.710	0.290
I68 Cerebrovascular disorders in diseases classified elsewhere	0.709	0.291
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.709	0.291
L05 Pilonidal cyst	0.709	0.291
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.707	0.292
K22.8 Other specified diseases of oesophagus	0.707	0.293
K75.8 Other specified inflammatory liver diseases	0.707	0.293
K27 Peptic ulcer, site unspecified	0.707	0.293
M86-M90 Other osteopathies	0.707	0.293
E11 Non-insulin-dependent diabetes mellitus	0.706	0.294
K76.0 Fatty (change of) liver, not elsewhere classified	0.706	0.294
I60 Subarachnoid haemorrhage	0.706	0.294
K31.5 Obstruction of duodenum	0.705	0.295
D60-D64 Aplastic and other anaemias	0.704	0.296
M49 Spondylopathies in diseases classified elsewhere	0.704	0.296
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.704	0.296
M47.99 Spondylosis, unspecified (Site unspecified)	0.703	0.297
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.702	0.298
D45 Polycythaemia vera	0.702	0.298
K74.6 Other and unspecified cirrhosis of liver	0.702	0.298
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.701	0.299
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.701	0.299
C40-C41 Malignant neoplasms of bone and articular cartilage	0.701	0.299
D12.2 Ascending colon	0.700	0.300
I33.0 Acute and subacute infective endocarditis	0.699	0.300
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.699	0.301
M93 Other osteochondropathies	0.699	0.301
I52 Other heart disorders in diseases classified elsewhere	0.699	0.301
I48 Atrial fibrillation and flutter	0.699	0.301
I43 Cardiomyopathy in diseases classified elsewhere	0.699	0.301
I41 Myocarditis in diseases classified elsewhere	0.699	0.301
I40 Acute myocarditis	0.699	0.301
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.699	0.301
I37 Pulmonary valve disorders	0.699	0.301
I32 Pericarditis in diseases classified elsewhere	0.699	0.301
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.698	0.302
D37.1 Stomach	0.698	0.302
K77 Liver disorders in diseases classified elsewhere	0.698	0.302
K73 Chronic hepatitis, not elsewhere classified	0.698	0.302
K71 Toxic liver disease	0.698	0.302
Z84 Family history of other conditions	0.698	0.302
Z81 Family history of mental and behavioural disorders	0.698	0.302
D80-D89 Certain disorders involving the immune mechanism	0.698	0.302
K31.1 Adult hypertrophic pyloric stenosis	0.697	0.303
M80-M85 Disorders of bone density and structure	0.697	0.303
N28.9 Disorder of kidney and ureter, unspecified	0.696	0.304
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.695	0.305
M54.8 Other dorsalgia	0.694	0.306
M54.6 Pain in thoracic spine	0.694	0.306
M54.0 Panniculitis affecting regions of neck and back	0.694	0.306
K55-K64 Other diseases of intestines	0.694	0.306
M48.09 Spinal stenosis (Site unspecified)	0.693	0.307
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.692	0.307
S27 Injury of other and unspecified intrathoracic organs	0.692	0.308
D03 Melanoma in situ	0.692	0.308
S01 Open wound of head	0.691	0.309
E40-E46 Malnutrition	0.690	0.310
M40-M43 Deforming dorsopathies	0.690	0.310
I70 Atherosclerosis	0.689	0.311
M54.99 Dorsalgia, unspecified (Site unspecified)	0.689	0.311
Z92.9 Personal history of medical treatment, unspecified	0.689	0.311
Z92.8 Personal history of other medical treatment	0.689	0.311
Z92.5 Personal history of rehabilitation measures	0.689	0.311
K74.0 Hepatic fibrosis	0.688	0.311
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.688	0.312
L20-L30 Dermatitis and eczema	0.688	0.312
M11 Other crystal arthropathies	0.687	0.313
D07 Carcinoma in situ of other and unspecified genital organs	0.687	0.313
Z95.3 Presence of xenogenic heart valve	0.686	0.314
D12.7 Rectosigmoid junction	0.686	0.314
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.685	0.315
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.685	0.315
I69.1 Sequelae of intracerebral haemorrhage	0.685	0.315
I69.0 Sequelae of subarachnoid haemorrhage	0.685	0.315
M10.97 Gout, unspecified (Ankle and foot)	0.684	0.316
S64.4 Injury of digital nerve of other finger	0.684	0.316
Q20-Q28 Congenital malformations of the circulatory system	0.684	0.316
O20 Haemorrhage in early pregnancy	0.683	0.317
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.683	0.317
D26 Other benign neoplasms of uterus	0.681	0.319
S42 Fracture of shoulder and upper arm	0.680	0.320
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.680	0.320
Chapter X Diseases of the respiratory system	0.679	0.321
V10-V19 Pedal cyclist injured in transport accident	0.679	0.321
B99-B99 Other infectious diseases	0.677	0.323
B90-B94 Sequelae of infectious and parasitic diseases	0.677	0.323
B85-B89 Pediculosis, acariasis and other infestations	0.677	0.323
B65-B83 Helminthiases	0.677	0.323
B50-B64 Protozoal diseases	0.677	0.323
B20-B24 Human immunodeficiency virus [HIV] disease	0.677	0.323
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.677	0.323
A80-A89 Viral infections of the central nervous system	0.677	0.323
A75-A79 Rickettsioses	0.677	0.323
A70-A74 Other diseases caused by chlamydiae	0.677	0.323
A65-A69 Other spirochaetal diseases	0.677	0.323
A50-A64 Infections with a predominantly sexual mode of transmission	0.677	0.323
A20-A28 Certain zoonotic bacterial diseases	0.677	0.323
A15-A19 Tuberculosis	0.677	0.323
N70.9 Salpingitis and oophoritis, unspecified	0.677	0.323
K90 Intestinal malabsorption	0.677	0.323
O80-O84 Delivery	0.676	0.324
M94 Other disorders of cartilage	0.676	0.324
M14 Arthropathies in other diseases classified elsewhere	0.676	0.324
M12 Other specific arthropathies	0.676	0.324
M09 Juvenile arthritis in diseases classified elsewhere	0.676	0.324
M08 Juvenile arthritis	0.676	0.324
K31.6 Fistula of stomach and duodenum	0.675	0.325
K31.4 Gastric diverticulum	0.675	0.325
K31.3 Pylorospasm, not elsewhere classified	0.675	0.325
K31.2 Hourglass stricture and stenosis of stomach	0.675	0.325
K31.0 Acute dilatation of stomach	0.675	0.325
Z80 Family history of malignant neoplasm	0.674	0.326
M47.80 Other spondylosis (Multiple sites in spine)	0.673	0.326
I45.5 Other specified heart block	0.673	0.327
M51.3 Other specified intervertebral disk degeneration	0.672	0.328
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.672	0.328
M51.9 Intervertebral disk disorder, unspecified	0.672	0.328
M51.8 Other specified intervertebral disk disorders	0.672	0.328
M51.4 Schmorl's nodes	0.672	0.328
K74.3 Primary biliary cirrhosis	0.672	0.328
D02 Carcinoma in situ of middle ear and respiratory system	0.672	0.328
D01 Carcinoma in situ of other and unspecified digestive organs	0.672	0.328
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.672	0.328
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.672	0.328
D14 Benign neoplasm of middle ear and respiratory system	0.672	0.328
L84 Corns and callosities	0.671	0.329
N18.5 Chronic kidney disease, stage 5	0.671	0.329
Q80-Q89 Other congenital malformations	0.670	0.330
N22 Calculus of urinary tract in diseases classified elsewhere	0.669	0.330
A00-A09 Intestinal infectious diseases	0.669	0.331
Z91 Personal history of risk-factors, not elsewhere classified	0.669	0.331
M47.1 Other spondylosis with myelopathy	0.669	0.331
M47.0 Anterior spinal and vertebral artery compression syndromes	0.669	0.331
N18.4 Chronic kidney disease, stage 4	0.669	0.331
S50-S59 Injuries to the elbow and forearm	0.668	0.332
M47.96 Spondylosis, unspecified (Lumbar region)	0.668	0.332
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.668	0.332
M45 Ankylosing spondylitis	0.668	0.332
D10 Benign neoplasm of mouth and pharynx	0.668	0.332
Z88.5 Personal history of allergy to narcotic agent	0.666	0.334
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.666	0.334
L81.9 Disorder of pigmentation, unspecified	0.665	0.335
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.664	0.335
K26.2 Acute with both haemorrhage and perforation	0.664	0.335
K26.1 Acute with perforation	0.664	0.335
K26.0 Acute with haemorrhage	0.664	0.335
Z88.1 Personal history of allergy to other antibiotic agents	0.664	0.336
N02.9 Unspecified	0.664	0.336
D31 Benign neoplasm of eye and adnexa	0.664	0.336
D30 Benign neoplasm of urinary organs	0.664	0.336
D29 Benign neoplasm of male genital organs	0.664	0.336
D28 Benign neoplasm of other and unspecified female genital organs	0.664	0.336
D21 Other benign neoplasms of connective and other soft tissue	0.664	0.336
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.664	0.336
D19 Benign neoplasm of mesothelial tissue	0.664	0.336
D16 Benign neoplasm of bone and articular cartilage	0.664	0.336
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.664	0.336
Z92.2 Personal history of long-term (current) use of other medicaments	0.664	0.336
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.663	0.337
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.663	0.337
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.663	0.337
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.663	0.337
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.663	0.337
I63.8 Other cerebral infarction	0.663	0.337
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.663	0.337
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.663	0.337
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.663	0.337
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.663	0.337
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.663	0.337
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.663	0.337
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.662	0.337
T92.1 Sequelae of fracture of arm	0.662	0.337
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.661	0.339
S68 Traumatic amputation of wrist and hand	0.661	0.339
B18 Chronic viral hepatitis	0.661	0.339
D37.5 Rectum	0.660	0.340
E87.6 Hypokalaemia	0.659	0.341
C60-C63 Malignant neoplasms of male genital organs	0.659	0.341
S62 Fracture at wrist and hand level	0.659	0.341
N72 Inflammatory disease of cervix uteri	0.658	0.342
S89 Other and unspecified injuries of lower leg	0.658	0.342
S88 Traumatic amputation of lower leg	0.658	0.342
S87 Crushing injury of lower leg	0.658	0.342
S86 Injury of muscle and tendon at lower leg level	0.658	0.342
S85 Injury of blood vessels at lower leg level	0.658	0.342
S84 Injury of nerves at lower leg level	0.658	0.342
C64-C68 Malignant neoplasms of urinary tract	0.658	0.342
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.657	0.343
D72 Other disorders of white blood cells	0.655	0.345
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.655	0.345
L44 Other papulosquamous disorders	0.655	0.345
L41 Parapsoriasis	0.655	0.345
L45 Papulosquamous disorders in diseases classified elsewhere	0.655	0.345
L42 Pityriasis rosea	0.655	0.345
M48.9 Spondylopathy, unspecified	0.655	0.345
M48.8 Other specified spondylopathies	0.655	0.345
M48.4 Fatigue fracture of vertebra	0.655	0.345
M48.3 Traumatic spondylopathy	0.655	0.345
M48.2 Kissing spine	0.655	0.345
M48.1 Ankylosing hyperostosis [Forestier]	0.655	0.345
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.654	0.346
N27 Small kidney of unknown cause	0.654	0.346
N25 Disorders resulting from impaired renal tubular function	0.654	0.346
N26 Unspecified contracted kidney	0.654	0.346
I20-I25 Ischaemic heart diseases	0.653	0.347
D37.4 Colon	0.653	0.347
A41.5 Septicaemia due to other Gram-negative organisms	0.653	0.347
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.652	0.348
K50.9 Crohn's disease, unspecified	0.652	0.348
S19 Other and unspecified injuries of neck	0.651	0.349
E65-E68 Obesity and other hyperalimentation	0.651	0.349
N18.8 Other chronic renal failure	0.651	0.349
N18.1 Chronic kidney disease, stage 1	0.651	0.349
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.651	0.349
D55-D59 Haemolytic anaemias	0.650	0.350
S80.8 Other superficial injuries of lower leg	0.650	0.350
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.649	0.351
Z76 Persons encountering health services in other circumstances	0.649	0.351
Z70 Counselling related to sexual attitude, behaviour and orientation	0.649	0.351
K52 Other non-infective gastro-enteritis and colitis	0.648	0.351
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.648	0.352
K51.2 Ulcerative (chronic) proctitis	0.648	0.352
Z97.8 Presence of other specified devices	0.647	0.353
M10.96 Gout, unspecified (Lower leg)	0.647	0.353
D32.9 Meninges, unspecified	0.646	0.354
T93 Sequelae of injuries of lower limb	0.646	0.354
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.646	0.354
L95 Vasculitis limited to skin, not elsewhere classified	0.646	0.354
L93 Lupus erythematosus	0.646	0.354
L87 Transepidermal elimination disorders	0.646	0.354
L88 Pyoderma gangrenosum	0.646	0.354
L86 Keratoderma in diseases classified elsewhere	0.646	0.354
L83 Acanthosis nigricans	0.646	0.354
L80 Vitiligo	0.646	0.354
Z88.4 Personal history of allergy to anaesthetic agent	0.645	0.355
F00-F09 Organic, including symptomatic, mental disorders	0.645	0.355
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.644	0.356
N73 Other female pelvic inflammatory diseases	0.644	0.356
L90.0 Lichen sclerosus et atrophicus	0.644	0.356
L04 Acute lymphadenitis	0.643	0.356
L01 Impetigo	0.643	0.356
L00 Staphylococcal scalded skin syndrome	0.643	0.356
D05.9 Carcinoma in situ of breast, unspecified	0.643	0.357
M10.4 Other secondary gout	0.643	0.357
M10.3 Gout due to impairment of renal function	0.643	0.357
M10.2 Drug-induced gout	0.643	0.357

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations