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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117898212
log Bayes Factor = 11.208
Chromosome 18   position 46,947,056  (GRCh37) Explore rs117898212 on Ensembl!
Variant rs117898212 is part of Cluster X0132

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
E10-E14 Diabetes mellitus
0.995 0.005 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.993 0.007 0.000
K55-K64 Other diseases of intestines
0.992 0.008 0.000
E11 Non-insulin-dependent diabetes mellitus
0.991 0.009 0.000
M50-M54 Other dorsopathies
0.990 0.010 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.988 0.012 0.000
K70-K77 Diseases of liver
0.985 0.015 0.000
S20-S29 Injuries to the thorax
0.980 0.020 0.000
M45-M49 Spondylopathies
0.976 0.024 0.000
Chapter VI Diseases of the nervous system
0.975 0.025 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.972 0.028 0.000
K14 Diseases of tongue
0.968 0.032 0.000
M54 Dorsalgia
0.966 0.034 0.000
K60 Fissure and fistula of anal and rectal regions
0.964 0.036 0.000
E11.3 With ophthalmic complications
0.958 0.042 0.000
Chapter VII Diseases of the eye and adnexa
0.951 0.049 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.949 0.051 0.000
E11.4 With neurological complications
0.946 0.054 0.000
H30-H36 Disorders of choroid and retina
0.944 0.056 0.000
K61 Abscess of anal and rectal regions
0.942 0.058 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.942 0.058 0.000
S90-S99 Injuries to the ankle and foot
0.941 0.059 0.000
M47 Spondylosis
0.941 0.059 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.940 0.060 0.000
H36 Retinal disorders in diseases classified elsewhere
0.936 0.064 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.936 0.064 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.933 0.067 0.000
H36.0 Diabetic retinopathy
0.931 0.069 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.929 0.071 0.000
K74 Fibrosis and cirrhosis of liver
0.921 0.079 0.000
E00-E07 Disorders of thyroid gland
0.921 0.079 0.000
M51 Other intervertebral disk disorders
0.920 0.080 0.000
S70-S79 Injuries to the hip and thigh
0.916 0.084 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.912 0.088 0.000
K14.0 Glossitis
0.911 0.089 0.000
M54.2 Cervicalgia
0.910 0.090 0.000
K60.1 Chronic anal fissure
0.906 0.094 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.903 0.097 0.000
K61.0 Anal abscess
0.902 0.098 0.000
K08 Other disorders of teeth and supporting structures
0.900 0.100 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.899 0.101 0.000
E50-E64 Other nutritional deficiencies
0.896 0.104 0.000
D50-D53 Nutritional anaemias
0.896 0.104 0.000
M70-M79 Other soft tissue disorders
0.895 0.105 0.000
K63 Other diseases of intestine
0.893 0.107 0.000
S22.4 Multiple fractures of ribs
0.892 0.108 0.000
S27 Injury of other and unspecified intrathoracic organs
0.891 0.109 0.000
M47.9 Spondylosis, unspecified
0.889 0.111 0.000
M54.1 Radiculopathy
0.889 0.111 0.000
K59 Other functional intestinal disorders
0.887 0.113 0.000
M86-M90 Other osteopathies
0.882 0.118 0.000
K11 Diseases of salivary glands
0.881 0.119 0.000
W00-W19 Falls
0.877 0.123 0.000
S40-S49 Injuries to the shoulder and upper arm
0.874 0.126 0.000
K74.6 Other and unspecified cirrhosis of liver
0.873 0.127 0.000
K10 Other diseases of jaws
0.871 0.128 0.000
M54.22 Cervicalgia (Cervical region)
0.870 0.130 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.869 0.131 0.000
K76 Other diseases of liver
0.864 0.136 0.000
E10 Insulin-dependent diabetes mellitus
0.861 0.139 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.858 0.142 0.000
M20-M25 Other joint disorders
0.857 0.143 0.000
E20-E35 Disorders of other endocrine glands
0.857 0.143 0.000
S22.40 Multiple fractures of ribs (closed)
0.857 0.143 0.000
S91 Open wound of ankle and foot
0.855 0.145 0.000
S00-S09 Injuries to the head
0.855 0.145 0.000
H33 Retinal detachments and breaks
0.855 0.145 0.000
K75 Other inflammatory liver diseases
0.851 0.149 0.000
K63.5 Polyp of colon
0.851 0.149 0.000
O60-O75 Complications of labour and delivery
0.849 0.151 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.846 0.154 0.000
E11.5 With peripheral circulatory complications
0.845 0.155 0.000
E53 Deficiency of other B group vitamins
0.845 0.155 0.000
K14.8 Other diseases of tongue
0.840 0.160 0.000
K60.3 Anal fistula
0.840 0.160 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.840 0.160 0.000
D50 Iron deficiency anaemia
0.839 0.161 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.837 0.163 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.835 0.165 0.000
H55-H59 Other disorders of eye and adnexa
0.835 0.165 0.000
E16 Other disorders of pancreatic internal secretion
0.834 0.166 0.000
E11.2 With renal complications
0.833 0.167 0.000
M51.2 Other specified intervertebral disk displacement
0.833 0.167 0.000
M40-M43 Deforming dorsopathies
0.830 0.170 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.829 0.171 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.829 0.171 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.824 0.176 0.000
E07 Other disorders of thyroid
0.824 0.176 0.000
M25 Other joint disorders, not elsewhere classified
0.824 0.176 0.000
K76.6 Portal hypertension
0.822 0.178 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.822 0.178 0.000
K31 Other diseases of stomach and duodenum
0.820 0.180 0.000
D50.9 Iron deficiency anaemia, unspecified
0.816 0.184 0.000
E11.6 With other specified complications
0.815 0.185 0.000
S10-S19 Injuries to the neck
0.814 0.186 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.812 0.188 0.000
S80-S89 Injuries to the knee and lower leg
0.810 0.190 0.000
K31.8 Other specified diseases of stomach and duodenum
0.810 0.190 0.000
Y84.8 Other medical procedures
0.808 0.192 0.000
E53.8 Deficiency of other specified B group vitamins
0.808 0.192 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.805 0.195 0.000
M54.16 Radiculopathy (Lumbar region)
0.805 0.195 0.000
K72 Hepatic failure, not elsewhere classified
0.805 0.195 0.000
W20-W49 Exposure to inanimate mechanical forces
0.803 0.197 0.000
M47.8 Other spondylosis
0.802 0.198 0.000
S70 Superficial injury of hip and thigh
0.801 0.199 0.000
M60-M63 Disorders of muscles
0.799 0.201 0.000
T66-T78 Other and unspecified effects of external causes
0.798 0.202 0.000
M46 Other inflammatory spondylopathies
0.797 0.203 0.000
K05 Gingivitis and periodontal diseases
0.797 0.203 0.000
D80-D89 Certain disorders involving the immune mechanism
0.795 0.205 0.000
M77 Other enthesopathies
0.791 0.209 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.790 0.210 0.000
K11.2 Sialoadenitis
0.789 0.210 0.000
M54.4 Lumbago with sciatica
0.789 0.211 0.000
M25.5 Pain in joint
0.787 0.213 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.787 0.213 0.000
O26.8 Other specified pregnancy-related conditions
0.786 0.214 0.000
M24 Other specific joint derangements
0.785 0.215 0.000
E16.2 Hypoglycaemia, unspecified
0.784 0.216 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.784 0.216 0.000
M80-M85 Disorders of bone density and structure
0.783 0.217 0.000
Chapter VIII Diseases of the ear and mastoid process
0.782 0.218 0.000
H33.0 Retinal detachment with retinal break
0.781 0.219 0.000
K02 Dental caries
0.780 0.220 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.778 0.222 0.000
G63.2 Diabetic polyneuropathy
0.778 0.222 0.000
O20 Haemorrhage in early pregnancy
0.776 0.224 0.000
K01 Embedded and impacted teeth
0.775 0.225 0.000
K26 Duodenal ulcer
0.773 0.227 0.000
S22.5 Flail chest
0.773 0.227 0.000
M45 Ankylosing spondylitis
0.771 0.228 0.000
Y43 Primarily systemic agents
0.771 0.229 0.000
K10.8 Other specified diseases of jaws
0.770 0.230 0.000
K60.0 Acute anal fissure
0.770 0.230 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.770 0.230 0.000
S42 Fracture of shoulder and upper arm
0.769 0.231 0.000
O00-O08 Pregnancy with abortive outcome
0.769 0.231 0.000
K07 Dentofacial anomalies [including malocclusion]
0.769 0.231 0.000
X50-X57 Overexertion, travel and privation
0.768 0.231 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.768 0.232 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.767 0.233 0.000
K14.9 Disease of tongue, unspecified
0.764 0.236 0.000
K59.3 Megacolon, not elsewhere classified
0.763 0.237 0.000
K09 Cysts of oral region, not elsewhere classified
0.763 0.237 0.000
S92 Fracture of foot, except ankle
0.763 0.237 0.000
S72 Fracture of femur
0.762 0.238 0.000
M51.4 Schmorl's nodes
0.760 0.240 0.000
M91-M94 Chondropathies
0.760 0.240 0.000
S90 Superficial injury of ankle and foot
0.760 0.240 0.000
V40-V49 Car occupant injured in transport accident
0.757 0.243 0.000
S27.1 Traumatic haemothorax
0.755 0.245 0.000
E07.9 Disorder of thyroid, unspecified
0.755 0.245 0.000
K59.0 Constipation
0.754 0.246 0.000
G59.0 Diabetic mononeuropathy
0.754 0.246 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.753 0.247 0.000
S29 Other and unspecified injuries of thorax
0.753 0.247 0.000
E40-E46 Malnutrition
0.752 0.248 0.000
M89 Other disorders of bone
0.751 0.249 0.000
S91.3 Open wound of other parts of foot
0.750 0.250 0.000
O24 Diabetes mellitus in pregnancy
0.749 0.251 0.000
K62 Other diseases of anus and rectum
0.748 0.252 0.000
X60-X84 Intentional self-harm
0.747 0.253 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.746 0.254 0.000
Y57 Other and unspecified drugs and medicaments
0.744 0.256 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.744 0.256 0.000
O23 Infections of genito-urinary tract in pregnancy
0.744 0.256 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.740 0.260 0.000
M54.3 Sciatica
0.739 0.261 0.000
W19 Unspecified fall
0.739 0.261 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.739 0.261 0.000
W50-W64 Exposure to animate mechanical forces
0.738 0.262 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.738 0.262 0.000
D73 Diseases of spleen
0.737 0.263 0.000
G70-G73 Diseases of myoneural junction and muscle
0.737 0.263 0.000
Y52 Agents primarily affecting the cardiovascular system
0.735 0.265 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.735 0.265 0.000
K75.8 Other specified inflammatory liver diseases
0.734 0.266 0.000
M86 Osteomyelitis
0.733 0.267 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.733 0.267 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.732 0.268 0.000
O16 Unspecified maternal hypertension
0.732 0.268 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.729 0.271 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.728 0.272 0.000
X20-X29 Contact with venomous animals and plants
0.726 0.273 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.726 0.274 0.000
E04 Other non-toxic goitre
0.725 0.275 0.000
S22.0 Fracture of thoracic vertebra
0.724 0.276 0.000
Chapter I Certain infectious and parasitic diseases
0.723 0.277 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.722 0.278 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.722 0.278 0.000
S27.2 Traumatic heamopneumothorax
0.722 0.278 0.000
S01 Open wound of head
0.721 0.279 0.000
H31 Other disorders of choroid
0.718 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.715 0.284 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.715 0.285 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.714 0.286 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
E12 Malnutrition-related diabetes mellitus
0.714 0.286 0.000
G62 Other polyneuropathies
0.714 0.286 0.000
S91.1 Open wound of toe(s) without damage to nail
0.714 0.286 0.000
K03 Other diseases of hard tissues of teeth
0.713 0.287 0.000
K00 Disorders of tooth development and eruption
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
Y00-Y09 Assault
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V80-V89 Other land transport accidents
0.712 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.288 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.711 0.288 0.000
E11.8 With unspecified complications
0.710 0.289 0.000
E11.7 With multiple complications
0.710 0.289 0.000
E11.1 With ketoacidosis
0.710 0.289 0.000
E11.0 With coma
0.710 0.289 0.000
K55 Vascular disorders of intestine
0.709 0.291 0.000
E10.4 With neurological complications
0.709 0.291 0.000
E13 Other specified diabetes mellitus
0.708 0.291 0.000
O85-O92 Complications predominantly related to the puerperium
0.708 0.292 0.000
K63.1 Perforation of intestine (nontraumatic)
0.707 0.293 0.000
T79-T79 Certain early complications of trauma
0.707 0.293 0.000
H57 Other disorders of eye and adnexa
0.707 0.293 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.706 0.294 0.000
K77 Liver disorders in diseases classified elsewhere
0.706 0.294 0.000
K73 Chronic hepatitis, not elsewhere classified
0.706 0.294 0.000
K71 Toxic liver disease
0.706 0.294 0.000
K80 Cholelithiasis
0.703 0.297 0.000
M71 Other bursopathies
0.703 0.297 0.000
K61.3 Ischiorectal abscess
0.703 0.297 0.000
S27.3 Other injuries of lung
0.703 0.297 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.703 0.297 0.000
S26 Injury of heart
0.703 0.297 0.000
S25 Injury of blood vessels of thorax
0.703 0.297 0.000
S24 Injury of nerves and spinal cord at thorax level
0.703 0.297 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.703 0.297 0.000
S21 Open wound of thorax
0.703 0.297 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.702 0.298 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.702 0.298 0.000
O62 Abnormalities of forces of labour
0.702 0.298 0.000
M25.8 Other specified joint disorders
0.702 0.298 0.000
S02 Fracture of skull and facial bones
0.701 0.299 0.000
K65-K67 Diseases of peritoneum
0.701 0.299 0.000
M77.1 Lateral epicondylitis
0.701 0.299 0.000
M49 Spondylopathies in diseases classified elsewhere
0.700 0.300 0.000
M25.50 Pain in joint (Multiple sites)
0.699 0.301 0.000
H80-H83 Diseases of inner ear
0.699 0.301 0.000
D55-D59 Haemolytic anaemias
0.697 0.303 0.000
E10.3 With ophthalmic complications
0.696 0.304 0.000
M48 Other spondylopathies
0.695 0.305 0.000
O20.0 Threatened abortion
0.695 0.305 0.000
S50-S59 Injuries to the elbow and forearm
0.695 0.305 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.695 0.305 0.000
K14.6 Glossodynia
0.694 0.306 0.000
K14.5 Plicated tongue
0.694 0.306 0.000
K14.4 Atrophy of tongue papillae
0.694 0.306 0.000
K14.3 Hypertrophy of tongue papillae
0.694 0.306 0.000
K14.2 Median rhomboid glossitis
0.694 0.306 0.000
K14.1 Geographic tongue
0.694 0.306 0.000
W07 Fall involving chair
0.694 0.306 0.000
M54.8 Other dorsalgia
0.693 0.307 0.000
M54.0 Panniculitis affecting regions of neck and back
0.693 0.307 0.000
K60.5 Anorectal fistula
0.691 0.309 0.000
K60.4 Rectal fistula
0.691 0.309 0.000
D68 Other coagulation defects
0.690 0.309 0.000
Y44 Agents primarily affecting blood constituents
0.690 0.310 0.000
H33.5 Other retinal detachments
0.689 0.311 0.000
M25.53 Pain in joint (Forearm)
0.688 0.312 0.000
M47.1 Other spondylosis with myelopathy
0.687 0.313 0.000
O80-O84 Delivery
0.687 0.313 0.000
S71 Open wound of hip and thigh
0.686 0.314 0.000
S20 Superficial injury of thorax
0.685 0.315 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.685 0.315 0.000
K31.4 Gastric diverticulum
0.684 0.316 0.000
O21 Excessive vomiting in pregnancy
0.683 0.317 0.000
D86 Sarcoidosis
0.683 0.317 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.683 0.317 0.000
K31.7 Polyp of stomach and duodenum
0.683 0.317 0.000
M47.86 Other spondylosis (Lumbar region)
0.682 0.318 0.000
K27 Peptic ulcer, site unspecified
0.681 0.318 0.000
G83 Other paralytic syndromes
0.681 0.319 0.000
M47.2 Other spondylosis with radiculopathy
0.681 0.319 0.000
G52 Disorders of other cranial nerves
0.680 0.320 0.000
W19.9 Unspecified place
0.680 0.320 0.000
D70 Agranulocytosis
0.679 0.321 0.000
K62.8 Other specified diseases of anus and rectum
0.679 0.321 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.679 0.321 0.000
D52 Folate deficiency anaemia
0.679 0.321 0.000
G54 Nerve root and plexus disorders
0.679 0.321 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.677 0.323 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.677 0.323 0.000
H30 Chorioretinal inflammation
0.677 0.323 0.000
S42.0 Fracture of clavicle
0.677 0.323 0.000
M43 Other deforming dorsopathies
0.677 0.323 0.000
M53 Other dorsopathies, not elsewhere classified
0.677 0.323 0.000
K74.3 Primary biliary cirrhosis
0.676 0.323 0.000
W18 Other fall on same level
0.676 0.324 0.000
M50 Cervical disk disorders
0.676 0.324 0.000
S22.3 Fracture of rib
0.676 0.324 0.000
S70.0 Contusion of hip
0.676 0.324 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.676 0.324 0.000
K61.4 Intrasphincteric abscess
0.675 0.325 0.000
K61.2 Anorectal abscess
0.675 0.325 0.000
K61.1 Rectal abscess
0.675 0.325 0.000
O29 Complications of anaesthesia during pregnancy
0.675 0.325 0.000
O28 Abnormal findings on antenatal screening of mother
0.675 0.325 0.000
O22 Venous complications in pregnancy
0.675 0.325 0.000
O25 Malnutrition in pregnancy
0.675 0.325 0.000
S99 Other and unspecified injuries of ankle and foot
0.675 0.325 0.000
S98 Traumatic amputation of ankle and foot
0.675 0.325 0.000
S97 Crushing injury of ankle and foot
0.675 0.325 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.675 0.325 0.000
S95 Injury of blood vessels at ankle and foot level
0.675 0.325 0.000
S94 Injury of nerves at ankle and foot level
0.675 0.325 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.675 0.325 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.674 0.325 0.000
S22.9 Fracture of bony thorax, part unspecified
0.674 0.326 0.000
S22.8 Fracture of other parts of bony thorax
0.674 0.326 0.000
S22.1 Multiple fractures of thoracic spine
0.674 0.326 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.674 0.326 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.674 0.326 0.000
K59.8 Other specified functional intestinal disorders
0.673 0.327 0.000
S79 Other and unspecified injuries of hip and thigh
0.673 0.327 0.000
M54.6 Pain in thoracic spine
0.672 0.328 0.000
E34 Other endocrine disorders
0.671 0.328 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.671 0.329 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.671 0.329 0.000
K63.9 Disease of intestine, unspecified
0.670 0.330 0.000
K62.4 Stenosis of anus and rectum
0.669 0.331 0.000
Y59 Other and unspecified vaccines and biological substances
0.669 0.331 0.000
Y58 Bacterial vaccines
0.669 0.331 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.669 0.331 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.669 0.331 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.669 0.331 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.669 0.331 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.669 0.331 0.000
Y48 Anaesthetics and therapeutic gases
0.669 0.331 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.669 0.331 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.669 0.331 0.000
E21.3 Hyperparathyroidism, unspecified
0.667 0.333 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.666 0.334 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.666 0.334 0.000
S80 Superficial injury of lower leg
0.665 0.335 0.000
K63.8 Other specified diseases of intestine
0.665 0.335 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.665 0.335 0.000
M79.6 Pain in limb
0.665 0.335 0.000
S10 Superficial injury of neck
0.665 0.335 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.663 0.337 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.662 0.338 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.662 0.338 0.000
Y84.4 Aspiration of fluid
0.662 0.338 0.000
K60.2 Anal fissure, unspecified
0.661 0.339 0.000
K74.5 Biliary cirrhosis, unspecified
0.660 0.340 0.000
K74.4 Secondary biliary cirrhosis
0.660 0.340 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.660 0.340 0.000
K74.1 Hepatic sclerosis
0.660 0.340 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.660 0.340 0.000
E00 Congenital iodine-deficiency syndrome
0.660 0.340 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.660 0.340 0.000
E10.2 With renal complications
0.660 0.340 0.000
M51.3 Other specified intervertebral disk degeneration
0.660 0.340 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.660 0.340 0.000
V20-V29 Motorcycle rider injured in transport accident
0.659 0.340 0.000
D75 Other diseases of blood and blood-forming organs
0.658 0.342 0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)
0.658 0.342 0.000
Y84.0 Cardiac catheterisation
0.658 0.342 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.657 0.342 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.657 0.342 0.000
M89.9 Disorder of bone, unspecified
0.657 0.343 0.000
S42.1 Fracture of scapula
0.657 0.343 0.000
K75.4 Autoimmune hepatitis
0.657 0.343 0.000
S78 Traumatic amputation of hip and thigh
0.657 0.343 0.000
S77 Crushing injury of hip and thigh
0.657 0.343 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.657 0.343 0.000
S75 Injury of blood vessels at hip and thigh level
0.657 0.343 0.000
S74 Injury of nerves at hip and thigh level
0.657 0.343 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.657 0.343 0.000
K74.0 Hepatic fibrosis
0.656 0.343 0.000
K10.2 Inflammatory conditions of jaws
0.656 0.344 0.000
S72.1 Pertrochanteric fracture
0.656 0.344 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.656 0.344 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.656 0.344 0.000
M62 Other disorders of muscle
0.655 0.344 0.000
K05.3 Chronic periodontitis
0.655 0.345 0.000
Y45.2 Propionic acid derivatives
0.655 0.345 0.000
Y43.3 Other antineoplastic drugs
0.655 0.345 0.000
O15 Eclampsia
0.654 0.346 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.654 0.346 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.654 0.346 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.654 0.346 0.000
M54.29 Cervicalgia-Site unspe
0.653 0.347 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.653 0.347 0.000
M54.27 Cervicalgia-Lumbosacral
0.653 0.347 0.000
M54.26 Cervicalgia-Lumbar
0.653 0.347 0.000
M54.25 Cervicalgia-Thoracolumbar
0.653 0.347 0.000
M54.24 Cervicalgia-Thoracic
0.653 0.347 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.653 0.347 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.653 0.347 0.000
M54.20 Cervicalgia-Mult site
0.653 0.347 0.000
S22.50 Flail chest (closed)
0.652 0.347 0.000
H43-H45 Disorders of vitreous body and globe
0.652 0.348 0.000
S27.0 Traumatic pneumothorax
0.651 0.349 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.651 0.349 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.651 0.349 0.000
D73.0 Hyposplenism
0.650 0.350 0.000
S92.0 Fracture of calcaneus
0.649 0.350 0.000
K11.8 Other diseases of salivary glands
0.648 0.352 0.000
G81 Hemiplegia
0.648 0.352 0.000
E15 Nondiabetic hypoglycaemic coma
0.647 0.353 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.647 0.353 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.646 0.353 0.000
M54.5 Low back pain
0.646 0.354 0.000
M54.12 Radiculopathy (Cervical region)
0.646 0.354 0.000
K11.5 Sialolithiasis
0.646 0.354 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.645 0.355 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.645 0.355 0.000
G60 Hereditary and idiopathic neuropathy
0.645 0.355 0.000
G64 Other disorders of peripheral nervous system
0.645 0.355 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.645 0.355 0.000
H55 Nystagmus and other irregular eye movements
0.644 0.356 0.000
M51.9 Intervertebral disk disorder, unspecified
0.644 0.356 0.000
G58 Other mononeuropathies
0.643 0.356 0.000
M65-M68 Disorders of synovium and tendon
0.643 0.357 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.642 0.357 0.000
E63 Other nutritional deficiencies
0.642 0.357 0.000
E56 Other vitamin deficiencies
0.642 0.357 0.000
E51 Thiamine deficiency
0.642 0.357 0.000
E50 Vitamin A deficiency
0.642 0.357 0.000
E60 Dietary zinc deficiency
0.642 0.357 0.000
E59 Dietary selenium deficiency
0.642 0.357 0.000
E58 Dietary calcium deficiency
0.642 0.357 0.000
E54 Ascorbic acid deficiency
0.642 0.357 0.000
E52 Niacin deficiency [pellagra]
0.642 0.357 0.000
D53 Other nutritional anaemias
0.642 0.358 0.000
M41 Scoliosis
0.642 0.358 0.000
M76 Enthesopathies of lower limb, excluding foot
0.642 0.358 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.642 0.358 0.000
S82 Fracture of lower leg, including ankle
0.642 0.358 0.000
K72.9 Hepatic failure, unspecified
0.641 0.358 0.000
M77.5 Other enthesopathy of foot
0.641 0.359 0.000
K63.4 Enteroptosis
0.640 0.359 0.000
K63.0 Abscess of intestine
0.640 0.359 0.000
M79.1 Myalgia
0.640 0.359 0.000
E10.1 With ketoacidosis
0.639 0.360 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.639 0.360 0.000
O73 Retained placenta and membranes, without haemorrhage
0.639 0.361 0.000
S22.41 Multiple fractures of ribs (open)
0.639 0.361 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.639 0.361 0.000
M25.9 Joint disorder, unspecified
0.639 0.361 0.000
S27.9 Injury of unspecified intrathoracic organ
0.639 0.361 0.000
S27.8 Injury of other specified intrathoracic organs
0.639 0.361 0.000
S27.7 Multiple injuries of intrathoracic organs
0.639 0.361 0.000
S27.6 Injury of pleura
0.639 0.361 0.000
S27.5 Injury of thoracic trachea
0.639 0.361 0.000
S27.4 Injury of bronchus
0.639 0.361 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.637 0.363 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.637 0.363 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.637 0.363 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.637 0.363 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.637 0.363 0.000
H10-H13 Disorders of conjunctiva
0.637 0.363 0.000
M54.19 Radiculopathy (Site unspecified)
0.637 0.363 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.637 0.363 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.637 0.363 0.000
M54.14 Radiculopathy (Thoracic region)
0.637 0.363 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.637 0.363 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.637 0.363 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.637 0.363 0.000
E21.0 Primary hyperparathyroidism
0.636 0.364 0.000
G30-G32 Other degenerative diseases of the nervous system
0.636 0.364 0.000
Chapter XXI Factors influencing health status and contact with health services
0.636 0.364 0.000
M72 Fibroblastic disorders
0.636 0.364 0.000
M79.7 Fibromyalgia
0.636 0.364 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.636 0.364 0.000
K59.9 Functional intestinal disorder, unspecified
0.636 0.364 0.000
K59.4 Anal spasm
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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