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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118097116
log Bayes Factor = 18.1078
Chromosome 11   position 74,447,931  (GRCh37) Explore rs118097116 on Ensembl!
Variant rs118097116 is part of Cluster X0059

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
J90-J94 Other diseases of pleura
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
J90 Pleural effusion, not elsewhere classified
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
Chapter II Neoplasms
0.995 0.005 0.000
Chapter XIV Diseases of the genitourinary system
0.993 0.007 0.000
M23 Internal derangement of knee
0.990 0.010 0.000
M20 Acquired deformities of fingers and toes
0.987 0.013 0.000
I30-I52 Other forms of heart disease
0.983 0.017 0.000
C60-C63 Malignant neoplasms of male genital organs
0.980 0.020 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.971 0.029 0.000
C61 Malignant neoplasm of prostate
0.970 0.030 0.000
N40-N51 Diseases of male genital organs
0.966 0.034 0.000
I60-I69 Cerebrovascular diseases
0.962 0.038 0.000
M15-M19 Arthrosis
0.961 0.039 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.960 0.040 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.959 0.041 0.000
M20.1 Hallux valgus (acquired)
0.959 0.041 0.000
S00-S09 Injuries to the head
0.957 0.043 0.000
M25 Other joint disorders, not elsewhere classified
0.953 0.047 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.952 0.048 0.000
Chapter VIII Diseases of the ear and mastoid process
0.952 0.048 0.000
B95-B98 Bacterial, viral and other infectious agents
0.951 0.049 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.948 0.052 0.000
M17 Gonarthrosis [arthrosis of knee]
0.946 0.054 0.000
M17.9 Gonarthrosis, unspecified
0.945 0.055 0.000
G40-G47 Episodic and paroxysmal disorders
0.943 0.057 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.942 0.058 0.000
I83 Varicose veins of lower extremities
0.941 0.059 0.000
A30-A49 Other bacterial diseases
0.937 0.063 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.934 0.066 0.000
G47 Sleep disorders
0.930 0.070 0.000
M25.7 Osteophyte
0.920 0.080 0.000
G47.3 Sleep apnoea
0.920 0.080 0.000
I63 Cerebral infarction
0.918 0.082 0.000
I47 Paroxysmal tachycardia
0.916 0.084 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.912 0.088 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.910 0.090 0.000
S60-S69 Injuries to the wrist and hand
0.907 0.093 0.000
D60-D64 Aplastic and other anaemias
0.907 0.093 0.000
C79 Secondary malignant neoplasm of other sites
0.906 0.094 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.905 0.095 0.000
G81 Hemiplegia
0.903 0.097 0.000
N00-N08 Glomerular diseases
0.898 0.101 0.000
N43 Hydrocele and spermatocele
0.896 0.104 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.894 0.106 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.893 0.107 0.000
I63.9 Cerebral infarction, unspecified
0.890 0.110 0.000
J93 Pneumothorax
0.885 0.115 0.000
A41 Other septicaemia
0.884 0.116 0.000
N40 Hyperplasia of prostate
0.884 0.116 0.000
M23.3 Other meniscus derangements
0.883 0.117 0.000
Chapter XX External causes of morbidity and mortality
0.875 0.125 0.000
N30-N39 Other diseases of urinary system
0.873 0.127 0.000
G81.9 Hemiplegia, unspecified
0.871 0.129 0.000
S00 Superficial injury of head
0.870 0.130 0.000
M40-M43 Deforming dorsopathies
0.862 0.138 0.000
I34 Nonrheumatic mitral valve disorders
0.856 0.144 0.000
H90-H95 Other disorders of ear
0.854 0.146 0.000
E10-E14 Diabetes mellitus
0.846 0.154 0.000
N43.3 Hydrocele, unspecified
0.845 0.155 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.843 0.157 0.000
G90-G99 Other disorders of the nervous system
0.841 0.159 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.840 0.160 0.000
N10-N16 Renal tubulo-interstitial diseases
0.840 0.160 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.839 0.161 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.839 0.161 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.838 0.162 0.000
D64 Other anaemias
0.835 0.165 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.833 0.167 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.833 0.167 0.000
N25-N29 Other disorders of kidney and ureter
0.831 0.169 0.000
C51-C58 Malignant neoplasms of female genital organs
0.829 0.171 0.000
S01 Open wound of head
0.827 0.173 0.000
Chapter XXI Factors influencing health status and contact with health services
0.825 0.175 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.824 0.176 0.000
I05-I09 Chronic rheumatic heart diseases
0.824 0.176 0.000
N03 Chronic nephritic syndrome
0.824 0.176 0.000
N45 Orchitis and epididymitis
0.823 0.177 0.000
N39 Other disorders of urinary system
0.822 0.178 0.000
S90-S99 Injuries to the ankle and foot
0.822 0.178 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.821 0.178 0.000
M23.8 Other internal derangements of knee
0.821 0.179 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.820 0.180 0.000
B02 Zoster [herpes zoster]
0.820 0.180 0.000
I31 Other diseases of pericardium
0.817 0.183 0.000
I47.1 Supraventricular tachycardia
0.817 0.183 0.000
M20.5 Other deformities of toe(s) (acquired)
0.816 0.184 0.000
I69 Sequelae of cerebrovascular disease
0.815 0.185 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.814 0.186 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.811 0.189 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.811 0.189 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.808 0.192 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.807 0.193 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.807 0.193 0.000
M25.76 Osteophyte (Lower leg)
0.807 0.193 0.000
H60-H62 Diseases of external ear
0.805 0.195 0.000
J93.9 Pneumothorax, unspecified
0.803 0.197 0.000
G20-G26 Extrapyramidal and movement disorders
0.803 0.197 0.000
N39.0 Urinary tract infection, site not specified
0.800 0.200 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.799 0.201 0.000
N99-N99 Other disorders of the genitourinary system
0.797 0.203 0.000
S64 Injury of nerves at wrist and hand level
0.797 0.203 0.000
J91 Pleural effusion in conditions classified elsewhere
0.796 0.204 0.000
S20-S29 Injuries to the thorax
0.796 0.204 0.000
M50-M54 Other dorsopathies
0.796 0.204 0.000
A41.9 Septicaemia, unspecified
0.795 0.205 0.000
S06 Intracranial injury
0.794 0.205 0.000
C64-C68 Malignant neoplasms of urinary tract
0.792 0.207 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.791 0.209 0.000
I47.2 Ventricular tachycardia
0.791 0.209 0.000
M25.72 Osteophyte (Upper arm)
0.791 0.209 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.790 0.210 0.000
I38 Endocarditis, valve unspecified
0.789 0.211 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.789 0.211 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.788 0.212 0.000
E20-E35 Disorders of other endocrine glands
0.786 0.214 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.785 0.215 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.785 0.215 0.000
M22 Disorders of patella
0.785 0.215 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.785 0.215 0.000
D64.9 Anaemia, unspecified
0.784 0.216 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.784 0.216 0.000
M20.2 Hallux rigidus
0.782 0.218 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.782 0.218 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.781 0.219 0.000
H91 Other hearing loss
0.779 0.221 0.000
J40-J47 Chronic lower respiratory diseases
0.778 0.222 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.778 0.222 0.000
M24 Other specific joint derangements
0.778 0.222 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.778 0.222 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.777 0.222 0.000
J60-J70 Lung diseases due to external agents
0.776 0.224 0.000
M25.78 Osteophyte (Other)
0.776 0.224 0.000
I34.0 Mitral (valve) insufficiency
0.773 0.227 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.771 0.229 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.770 0.230 0.000
N03.9 Unspecified
0.770 0.230 0.000
G70-G73 Diseases of myoneural junction and muscle
0.768 0.232 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.766 0.234 0.000
I49 Other cardiac arrhythmias
0.765 0.235 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.764 0.236 0.000
J95-J99 Other diseases of the respiratory system
0.763 0.237 0.000
C80 Malignant neoplasm without specification of site
0.763 0.237 0.000
C79.6 Secondary malignant neoplasm of ovary
0.762 0.238 0.000
B35-B49 Mycoses
0.761 0.239 0.000
I33 Acute and subacute endocarditis
0.761 0.239 0.000
G30-G32 Other degenerative diseases of the nervous system
0.761 0.239 0.000
T66-T78 Other and unspecified effects of external causes
0.761 0.239 0.000
S10-S19 Injuries to the neck
0.761 0.239 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.761 0.239 0.000
S40-S49 Injuries to the shoulder and upper arm
0.759 0.241 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.759 0.241 0.000
D80-D89 Certain disorders involving the immune mechanism
0.759 0.241 0.000
I10-I15 Hypertensive diseases
0.759 0.241 0.000
I45 Other conduction disorders
0.757 0.243 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.756 0.244 0.000
M19 Other arthrosis
0.755 0.245 0.000
S00.8 Superficial injury of other parts of head
0.755 0.245 0.000
H65-H75 Diseases of middle ear and mastoid
0.754 0.246 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.754 0.246 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.753 0.247 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.753 0.247 0.000
I51 Complications and ill-defined descriptions of heart disease
0.752 0.248 0.000
M25.5 Pain in joint
0.751 0.249 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.750 0.250 0.000
S80-S89 Injuries to the knee and lower leg
0.749 0.251 0.000
N75 Diseases of Bartholin's gland
0.748 0.252 0.000
E10 Insulin-dependent diabetes mellitus
0.747 0.253 0.000
D61 Other aplastic anaemias
0.747 0.253 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.747 0.253 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.746 0.254 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.743 0.257 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.743 0.257 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.743 0.257 0.000
M05-M14 Inflammatory polyarthropathies
0.743 0.257 0.000
J92 Pleural plaque
0.740 0.260 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.740 0.260 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.738 0.262 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.738 0.262 0.000
Y84.8 Other medical procedures
0.738 0.262 0.000
C56 Malignant neoplasm of ovary
0.737 0.263 0.000
Chapter XXII Codes for special purposes
0.737 0.263 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.736 0.264 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.736 0.264 0.000
B07 Viral warts
0.736 0.264 0.000
M20.3 Other deformity of hallux (acquired)
0.736 0.264 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.735 0.265 0.000
A46 Erysipelas
0.733 0.267 0.000
D00-D09 In situ neoplasms
0.731 0.269 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.731 0.269 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.730 0.270 0.000
C79.2 Secondary malignant neoplasm of skin
0.730 0.270 0.000
Z72 Problems related to lifestyle
0.730 0.270 0.000
G80 Infantile cerebral palsy
0.728 0.272 0.000
S00.9 Superficial injury of head, part unspecified
0.728 0.272 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.728 0.272 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.728 0.272 0.000
I31.3 Pericardial effusion (noninflammatory)
0.727 0.273 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.727 0.273 0.000
I87 Other disorders of veins
0.726 0.273 0.000
H91.9 Hearing loss, unspecified
0.725 0.275 0.000
S02 Fracture of skull and facial bones
0.725 0.275 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.725 0.275 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.723 0.277 0.000
M86-M90 Other osteopathies
0.723 0.277 0.000
I50 Heart failure
0.723 0.277 0.000
J44 Other chronic obstructive pulmonary disease
0.723 0.277 0.000
M41 Scoliosis
0.722 0.278 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.720 0.280 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.720 0.280 0.000
I35 Nonrheumatic aortic valve disorders
0.720 0.280 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.720 0.280 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.718 0.281 0.000
I42 Cardiomyopathy
0.718 0.282 0.000
M54 Dorsalgia
0.718 0.282 0.000
H80-H83 Diseases of inner ear
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M34 Systemic sclerosis
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
M21 Other acquired deformities of limbs
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
J94 Other pleural conditions
0.716 0.284 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.715 0.285 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.715 0.285 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.714 0.286 0.000
B99-B99 Other infectious diseases
0.714 0.286 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B65-B83 Helminthiases
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
B15-B19 Viral hepatitis
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.713 0.287 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.713 0.287 0.000
G47.9 Sleep disorder, unspecified
0.713 0.287 0.000
M18 Arthrosis of first carpometacarpal joint
0.712 0.288 0.000
C62 Malignant neoplasm of testis
0.711 0.289 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.711 0.289 0.000
S67 Crushing injury of wrist and hand
0.710 0.290 0.000
E14 Unspecified diabetes mellitus
0.710 0.290 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.710 0.290 0.000
M23.9 Internal derangement of knee, unspecified
0.710 0.290 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.710 0.290 0.000
M23.5 Chronic instability of knee
0.710 0.290 0.000
M23.1 Discoid meniscus (congenital)
0.710 0.290 0.000
M23.0 Cystic meniscus
0.710 0.290 0.000
T79-T79 Certain early complications of trauma
0.709 0.291 0.000
M20.0 Deformity of finger(s)
0.707 0.293 0.000
S01.8 Open wound of other parts of head
0.706 0.294 0.000
N48 Other disorders of penis
0.706 0.294 0.000
N35 Urethral stricture
0.705 0.294 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.705 0.295 0.000
I52 Other heart disorders in diseases classified elsewhere
0.705 0.295 0.000
I48 Atrial fibrillation and flutter
0.705 0.295 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.705 0.295 0.000
I41 Myocarditis in diseases classified elsewhere
0.705 0.295 0.000
I40 Acute myocarditis
0.705 0.295 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.705 0.295 0.000
I37 Pulmonary valve disorders
0.705 0.295 0.000
I36 Nonrheumatic tricuspid valve disorders
0.705 0.295 0.000
I32 Pericarditis in diseases classified elsewhere
0.705 0.295 0.000
I30 Acute pericarditis
0.705 0.295 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.703 0.297 0.000
C60 Malignant neoplasm of penis
0.703 0.297 0.000
B02.9 Zoster without complication
0.702 0.298 0.000
I61 Intracerebral haemorrhage
0.702 0.298 0.000
B25-B34 Other viral diseases
0.702 0.298 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.700 0.300 0.000
H61 Other disorders of external ear
0.699 0.301 0.000
M23.4 Loose body in knee
0.699 0.301 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.698 0.302 0.000
J81 Pulmonary oedema
0.698 0.302 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.697 0.303 0.000
I60 Subarachnoid haemorrhage
0.697 0.303 0.000
T87 Complications peculiar to reattachment and amputation
0.696 0.303 0.000
T86 Failure and rejection of transplanted organs and tissues
0.696 0.303 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.696 0.303 0.000
I62 Other nontraumatic intracranial haemorrhage
0.695 0.304 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.695 0.305 0.000
M25.77 Osteophyte (Ankle and foot)
0.695 0.305 0.000
M25.71 Osteophyte (Shoulder region)
0.694 0.306 0.000
C34 Malignant neoplasm of bronchus and lung
0.693 0.307 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.693 0.307 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.693 0.307 0.000
N46 Male infertility
0.693 0.307 0.000
N44 Torsion of testis
0.693 0.307 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.693 0.307 0.000
B02.3 Zoster ocular disease
0.692 0.308 0.000
G83 Other paralytic syndromes
0.691 0.308 0.000
M45-M49 Spondylopathies
0.691 0.309 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.691 0.309 0.000
M43 Other deforming dorsopathies
0.690 0.310 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.689 0.310 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.689 0.310 0.000
M15 Polyarthrosis
0.689 0.311 0.000
Z72.1 Alcohol use
0.689 0.311 0.000
D55-D59 Haemolytic anaemias
0.688 0.312 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.688 0.312 0.000
S64.3 Injury of digital nerve of thumb
0.687 0.313 0.000
S08 Traumatic amputation of part of head
0.686 0.314 0.000
S07 Crushing injury of head
0.686 0.314 0.000
S05 Injury of eye and orbit
0.686 0.314 0.000
S04 Injury of cranial nerves
0.686 0.314 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.686 0.314 0.000
S00.1 Contusion of eyelid and periocular area
0.686 0.314 0.000
T92 Sequelae of injuries of upper limb
0.685 0.315 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.685 0.315 0.000
M70-M79 Other soft tissue disorders
0.684 0.316 0.000
S32 Fracture of lumbar spine and pelvis
0.683 0.317 0.000
M25.9 Joint disorder, unspecified
0.683 0.317 0.000
M25.8 Other specified joint disorders
0.683 0.317 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.683 0.317 0.000
M25.3 Other instability of joint
0.683 0.317 0.000
M25.2 Flail joint
0.683 0.317 0.000
M25.1 Fistula of joint
0.683 0.317 0.000
M25.0 Haemarthrosis
0.683 0.317 0.000
I88 Nonspecific lymphadenitis
0.683 0.317 0.000
I86 Varicose veins of other sites
0.683 0.317 0.000
I81 Portal vein thrombosis
0.683 0.317 0.000
S70-S79 Injuries to the hip and thigh
0.682 0.318 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.681 0.319 0.000
G82 Paraplegia and tetraplegia
0.679 0.320 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.679 0.321 0.000
M17.5 Other secondary gonarthrosis
0.678 0.321 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.678 0.321 0.000
M17.3 Other posttraumatic gonarthrosis
0.678 0.321 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.678 0.321 0.000
Y84.4 Aspiration of fluid
0.679 0.321 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.678 0.322 0.000
N05 Unspecified nephritic syndrome
0.678 0.322 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.678 0.322 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.677 0.323 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.677 0.323 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.676 0.324 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.676 0.324 0.000
G41 Status epilepticus
0.676 0.324 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.676 0.324 0.000
S68 Traumatic amputation of wrist and hand
0.676 0.324 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.675 0.325 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.675 0.325 0.000
R25 Abnormal involuntary movements
0.674 0.326 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.672 0.328 0.000
A48 Other bacterial diseases, not elsewhere classified
0.672 0.328 0.000
A44 Bartonellosis
0.672 0.328 0.000
A43 Nocardiosis
0.672 0.328 0.000
A42 Actinomycosis
0.672 0.328 0.000
A40 Streptococcal septicaemia
0.672 0.328 0.000
A39 Meningococcal infection
0.672 0.328 0.000
A37 Whooping cough
0.672 0.328 0.000
A36 Diphtheria
0.672 0.328 0.000
A32 Listeriosis
0.672 0.328 0.000
A31 Infection due to other mycobacteria
0.672 0.328 0.000
A30 Leprosy [Hansen's disease]
0.672 0.328 0.000
A38 Scarlet fever
0.672 0.328 0.000
A35 Other tetanus
0.672 0.328 0.000
A34 Obstetrical tetanus
0.672 0.328 0.000
A33 Tetanus neonatorum
0.672 0.328 0.000
I82 Other venous embolism and thrombosis
0.672 0.328 0.000
N04 Nephrotic syndrome
0.671 0.328 0.000
I12 Hypertensive renal disease
0.671 0.329 0.000
H65 Nonsuppurative otitis media
0.670 0.330 0.000
A49 Bacterial infection of unspecified site
0.669 0.331 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.669 0.331 0.000
N75.0 Cyst of Bartholin's gland
0.668 0.332 0.000
I08 Multiple valve diseases
0.667 0.333 0.000
E65-E68 Obesity and other hyperalimentation
0.667 0.333 0.000
G47.8 Other sleep disorders
0.667 0.333 0.000
G47.4 Narcolepsy and cataplexy
0.667 0.333 0.000
G47.2 Disorders of the sleep-wake schedule
0.667 0.333 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.667 0.333 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.667 0.333 0.000
I80 Phlebitis and thrombophlebitis
0.667 0.333 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.666 0.334 0.000
S62 Fracture at wrist and hand level
0.666 0.334 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.666 0.334 0.000
G44 Other headache syndromes
0.665 0.335 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.665 0.335 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.664 0.336 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.664 0.336 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.664 0.336 0.000
E11 Non-insulin-dependent diabetes mellitus
0.663 0.337 0.000
S50-S59 Injuries to the elbow and forearm
0.663 0.337 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.663 0.337 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.663 0.337 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.662 0.338 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.662 0.338 0.000
M25.79 Osteophyte (Site unspecified)
0.660 0.340 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.660 0.340 0.000
M25.74 Osteophyte (Hand)
0.660 0.340 0.000
M25.73 Osteophyte (Forearm)
0.660 0.340 0.000
M25.70 Osteophyte (Multiple sites)
0.660 0.340 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.659 0.341 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.658 0.341 0.000
I63.8 Other cerebral infarction
0.658 0.341 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.658 0.341 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.658 0.341 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.658 0.341 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.658 0.341 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.658 0.341 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.658 0.341 0.000
G25 Other extrapyramidal and movement disorders
0.657 0.342 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.657 0.343 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.657 0.343 0.000
I47.0 Reentry ventricular arrhythmia
0.657 0.343 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.656 0.344 0.000
S01.4 Open wound of cheek and temporomandibular area
0.656 0.344 0.000
G95 Other diseases of spinal cord
0.656 0.344 0.000
N13 Obstructive and reflux uropathy
0.655 0.345 0.000
V10-V19 Pedal cyclist injured in transport accident
0.654 0.346 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.654 0.346 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.654 0.346 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.654 0.346 0.000
R47-R49 Symptoms and signs involving speech and voice
0.654 0.346 0.000
M65-M68 Disorders of synovium and tendon
0.653 0.347 0.000
N39.9 Disorder of urinary system, unspecified
0.653 0.347 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.652 0.347 0.000
B06 Rubella [German measles]
0.652 0.347 0.000
B05 Measles
0.652 0.347 0.000
B01 Varicella [chickenpox]
0.652 0.347 0.000
B00 Herpesviral [herpes simplex] infections
0.652 0.347 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.652 0.347 0.000
B04 Monkeypox
0.652 0.347 0.000
B03 Smallpox
0.652 0.347 0.000
I51.9 Heart disease, unspecified
0.651 0.349 0.000
H90 Conductive and sensorineural hearing loss
0.651 0.349 0.000
S69 Other and unspecified injuries of wrist and hand
0.650 0.349 0.000
S65 Injury of blood vessels at wrist and hand level
0.650 0.349 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.650 0.349 0.000
S60 Superficial injury of wrist and hand
0.650 0.349 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.650 0.350 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.650 0.350 0.000
S92 Fracture of foot, except ankle
0.649 0.351 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.649 0.351 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.649 0.351 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.649 0.351 0.000
E40-E46 Malnutrition
0.649 0.351 0.000
N76 Other inflammation of vagina and vulva
0.648 0.352 0.000
G81.1 Spastic hemiplegia
0.647 0.353 0.000
G81.0 Flaccid hemiplegia
0.647 0.353 0.000
S01.0 Open wound of scalp
0.646 0.354 0.000
C45 Mesothelioma
0.646 0.354 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.645 0.355 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.645 0.355 0.000
M31 Other necrotising vasculopathies
0.645 0.355 0.000
D62 Acute posthaemorrhagic anaemia
0.645 0.355 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.644 0.356 0.000
N06 Isolated proteinuria with specified morphological lesion
0.644 0.356 0.000
N01 Rapidly progressive nephritic syndrome
0.644 0.356 0.000
N00 Acute nephritic syndrome
0.644 0.356 0.000
M54.9 Dorsalgia, unspecified
0.644 0.356 0.000
D68 Other coagulation defects
0.644 0.356 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.643 0.356 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.643 0.357 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.643 0.357 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.643 0.357 0.000
N43.4 Spermatocele
0.642 0.358 0.000
N43.2 Other hydrocele
0.642 0.358 0.000
N43.1 Infected hydrocele
0.642 0.358 0.000
N43.0 Encysted hydrocele
0.642 0.358 0.000
M19.9 Arthrosis, unspecified
0.642 0.358 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.641 0.359 0.000
N36 Other disorders of urethra
0.641 0.359 0.000
Z74 Problems related to care-provider dependency
0.641 0.359 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.641 0.359 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.641 0.359 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.641 0.359 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.640 0.360 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.640 0.360 0.000
T85.2 Mechanical complication of intraocular lens
0.640 0.360 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.640 0.360 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.640 0.360 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.640 0.360 0.000
S06.3 Focal brain injury
0.638 0.362 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.638 0.362 0.000
I07 Rheumatic tricuspid valve diseases
0.638 0.362 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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