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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11814448
log Bayes Factor = 0.651102
Chromosome 10   position 22,315,843  (GRCh37) Explore rs11814448 on Ensembl!
Variant rs11814448 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.767 0.233 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.766 0.234 0.000
# Top node
0.759 0.241 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.752 0.248 0.000
Chapter II Neoplasms
0.746 0.254 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.745 0.255 0.000
C15-C26 Malignant neoplasms of digestive organs
0.731 0.269 0.000
O60-O75 Complications of labour and delivery
0.728 0.272 0.000
Chapter XX External causes of morbidity and mortality
0.722 0.278 0.000
T39.1 4-Aminophenol derivatives
0.711 0.289 0.000
C50-C50 Malignant neoplasm of breast
0.703 0.297 0.000
C25 Malignant neoplasm of pancreas
0.695 0.304 0.000
Chapter XIV Diseases of the genitourinary system
0.691 0.309 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.688 0.312 0.000
Chapter VII Diseases of the eye and adnexa
0.682 0.318 0.000
O63 Long labour
0.676 0.324 0.000
C50 Malignant neoplasm of breast
0.672 0.328 0.000
N10-N16 Renal tubulo-interstitial diseases
0.671 0.329 0.000
N40-N51 Diseases of male genital organs
0.666 0.334 0.000
S60-S69 Injuries to the wrist and hand
0.665 0.335 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.660 0.340 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.658 0.342 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.655 0.345 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.654 0.346 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.652 0.348 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.647 0.353 0.000
N13 Obstructive and reflux uropathy
0.645 0.355 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.644 0.356 0.000
Chapter VIII Diseases of the ear and mastoid process
0.642 0.358 0.000
C50.9 Breast, unspecified
0.641 0.359 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.639 0.361 0.000
T92 Sequelae of injuries of upper limb
0.637 0.363 0.000
O00-O08 Pregnancy with abortive outcome
0.637 0.363 0.000
T39.0 Salicylates
0.637 0.363 0.000
S70-S79 Injuries to the hip and thigh
0.634 0.366 0.000
C25.0 Head of pancreas
0.631 0.369 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.628 0.372 0.000
N42 Other disorders of prostate
0.625 0.375 0.000
N60-N64 Disorders of breast
0.621 0.379 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.619 0.380 0.000
C25.9 Pancreas, unspecified
0.618 0.382 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.614 0.386 0.000
C18 Malignant neoplasm of colon
0.612 0.388 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.610 0.390 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.609 0.391 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.608 0.392 0.000
O63.1 Prolonged second stage (of labour)
0.604 0.396 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.603 0.397 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.601 0.399 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.596 0.404 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.595 0.405 0.000
M20-M25 Other joint disorders
0.595 0.405 0.000
C34 Malignant neoplasm of bronchus and lung
0.595 0.405 0.000
T92.1 Sequelae of fracture of arm
0.592 0.408 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.591 0.409 0.000
H90-H95 Other disorders of ear
0.589 0.411 0.000
O66 Other obstructed labour
0.589 0.411 0.000
N60 Benign mammary dysplasia
0.586 0.414 0.000
S61 Open wound of wrist and hand
0.585 0.415 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.581 0.419 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.580 0.420 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.579 0.421 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.577 0.423 0.000
O63.0 Prolonged first stage (of labour)
0.576 0.424 0.000
M70-M79 Other soft tissue disorders
0.576 0.424 0.000
C50.8 Overlapping lesion of breast
0.576 0.424 0.000
C15 Malignant neoplasm of oesophagus
0.574 0.426 0.000
S20-S29 Injuries to the thorax
0.574 0.426 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.569 0.431 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.566 0.434 0.000
M80-M85 Disorders of bone density and structure
0.566 0.434 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.566 0.434 0.000
N48 Other disorders of penis
0.566 0.434 0.000
N42.8 Other specified disorders of prostate
0.563 0.437 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.562 0.438 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.562 0.438 0.000
S90-S99 Injuries to the ankle and foot
0.561 0.439 0.000
N13.4 Hydroureter
0.559 0.441 0.000
H10-H13 Disorders of conjunctiva
0.559 0.441 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.558 0.442 0.000
C20 Malignant neoplasm of rectum
0.558 0.442 0.000
V20-V29 Motorcycle rider injured in transport accident
0.557 0.442 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.557 0.443 0.000
N13.3 Other and unspecified hydronephrosis
0.556 0.444 0.000
O61 Failed induction of labour
0.555 0.445 0.000
N41 Inflammatory diseases of prostate
0.552 0.448 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.551 0.449 0.000
C50.1 Central portion of breast
0.551 0.449 0.000
T33-T35 Frostbite
0.550 0.450 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.550 0.450 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.550 0.450 0.000
T00-T07 Injuries involving multiple body regions
0.550 0.450 0.000
S10-S19 Injuries to the neck
0.550 0.450 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.550 0.450 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.550 0.450 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.550 0.450 0.000
O80-O84 Delivery
0.550 0.450 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.549 0.450 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.549 0.450 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.549 0.450 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.549 0.450 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.549 0.450 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.549 0.450 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.549 0.450 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.549 0.450 0.000
T36 Poisoning by systemic antibiotics
0.549 0.450 0.000
M23 Internal derangement of knee
0.548 0.452 0.000
T51 Toxic effect of alcohol
0.548 0.452 0.000
S80-S89 Injuries to the knee and lower leg
0.547 0.453 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.547 0.453 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.546 0.454 0.000
T79-T79 Certain early complications of trauma
0.546 0.454 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.544 0.456 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.543 0.457 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.543 0.457 0.000
C34.1 Upper lobe, bronchus or lung
0.542 0.458 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.542 0.458 0.000
O04 Medical abortion
0.541 0.459 0.000
H43-H45 Disorders of vitreous body and globe
0.541 0.459 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.540 0.460 0.000
E00-E07 Disorders of thyroid gland
0.540 0.460 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.540 0.460 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.539 0.461 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.539 0.461 0.000
T39.4 Antirheumatics, not elsewhere classified
0.539 0.461 0.000
T39.2 Pyrazolone derivatives
0.539 0.461 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.539 0.461 0.000
T66-T78 Other and unspecified effects of external causes
0.538 0.462 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.537 0.463 0.000
S72 Fracture of femur
0.537 0.463 0.000
W20-W49 Exposure to inanimate mechanical forces
0.536 0.464 0.000
Chapter XXII Codes for special purposes
0.535 0.465 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.535 0.465 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.535 0.465 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.535 0.465 0.000
Y52 Agents primarily affecting the cardiovascular system
0.534 0.466 0.000
O85-O92 Complications predominantly related to the puerperium
0.534 0.466 0.000
T40.2 Other opioids
0.534 0.466 0.000
N50 Other disorders of male genital organs
0.534 0.466 0.000
H91 Other hearing loss
0.533 0.467 0.000
T42.4 Benzodiazepines
0.532 0.468 0.000
H40-H42 Glaucoma
0.532 0.468 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.532 0.468 0.000
T40.4 Other synthetic narcotics
0.530 0.470 0.000
H80-H83 Diseases of inner ear
0.528 0.471 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.528 0.472 0.000
X60-X84 Intentional self-harm
0.528 0.472 0.000
S69 Other and unspecified injuries of wrist and hand
0.528 0.472 0.000
Chapter VI Diseases of the nervous system
0.528 0.472 0.000
C16 Malignant neoplasm of stomach
0.526 0.474 0.000
C50.2 Upper-inner quadrant of breast
0.526 0.474 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.524 0.476 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.524 0.476 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.524 0.476 0.000
C21 Malignant neoplasm of anus and anal canal
0.524 0.476 0.000
C17 Malignant neoplasm of small intestine
0.524 0.476 0.000
C23 Malignant neoplasm of gallbladder
0.524 0.476 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.523 0.476 0.000
E50-E64 Other nutritional deficiencies
0.523 0.477 0.000
O74 Complications of anaesthesia during labour and delivery
0.522 0.478 0.000
O73 Retained placenta and membranes, without haemorrhage
0.522 0.478 0.000
O71 Other obstetric trauma
0.522 0.478 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.522 0.478 0.000
O62 Abnormalities of forces of labour
0.522 0.478 0.000
O60 Preterm delivery
0.522 0.478 0.000
Y42.5 Other oestrogens and progestogens
0.521 0.478 0.000
D68 Other coagulation defects
0.520 0.480 0.000
N42.1 Congestion and haemorrhage of prostate
0.520 0.480 0.000
Y57 Other and unspecified drugs and medicaments
0.520 0.480 0.000
S40-S49 Injuries to the shoulder and upper arm
0.520 0.480 0.000
Y85 Sequelae of transport accidents
0.520 0.480 0.000
H53-H54 Visual disturbances and blindness
0.519 0.481 0.000
S50-S59 Injuries to the elbow and forearm
0.518 0.482 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.518 0.482 0.000
Y35-Y36 Legal intervention and operations of war
0.518 0.482 0.000
Y10-Y34 Event of undetermined intent
0.518 0.482 0.000
Y00-Y09 Assault
0.518 0.482 0.000
X85-X99 Assault
0.518 0.482 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.518 0.482 0.000
X50-X57 Overexertion, travel and privation
0.518 0.482 0.000
X30-X39 Exposure to forces of nature
0.518 0.482 0.000
X20-X29 Contact with venomous animals and plants
0.518 0.482 0.000
X10-X19 Contact with heat and hot substances
0.518 0.482 0.000
X00-X09 Exposure to smoke, fire and flames
0.518 0.482 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.518 0.482 0.000
W75-W84 Other accidental threats to breathing
0.518 0.482 0.000
W65-W74 Accidental drowning and submersion
0.518 0.482 0.000
W50-W64 Exposure to animate mechanical forces
0.518 0.482 0.000
V98-V99 Other and unspecified transport accidents
0.518 0.482 0.000
V95-V97 Air and space transport accidents
0.518 0.482 0.000
V90-V94 Water transport accidents
0.518 0.482 0.000
V80-V89 Other land transport accidents
0.518 0.482 0.000
V70-V79 Bus occupant injured in transport accident
0.518 0.482 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.518 0.482 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.518 0.482 0.000
V40-V49 Car occupant injured in transport accident
0.518 0.482 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.518 0.482 0.000
V01-V09 Pedestrian injured in transport accident
0.518 0.482 0.000
M23.3 Other meniscus derangements
0.518 0.482 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.517 0.483 0.000
C91 Lymphoid leukaemia
0.516 0.484 0.000
Y95 Nosocomial condition
0.515 0.485 0.000
S61.0 Open wound of finger(s) without damage to nail
0.513 0.487 0.000
E20-E35 Disorders of other endocrine glands
0.511 0.489 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.509 0.491 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.509 0.491 0.000
H25-H28 Disorders of lens
0.507 0.493 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.507 0.493 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.503 0.496 0.000
N43 Hydrocele and spermatocele
0.503 0.497 0.000
N60.3 Fibrosclerosis of breast
0.502 0.498 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.501 0.499 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.501 0.499 0.000
C18.4 Transverse colon
0.500 0.500 0.000
C25.8 Overlapping lesion of pancreas
0.499 0.501 0.000
C25.7 Other parts of pancreas
0.499 0.501 0.000
C25.4 Endocrine pancreas
0.499 0.501 0.000
C25.3 Pancreatic duct
0.499 0.501 0.000
C25.2 Tail of pancreas
0.499 0.501 0.000
C25.1 Body of pancreas
0.499 0.501 0.000
H55-H59 Other disorders of eye and adnexa
0.499 0.501 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.498 0.502 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.497 0.503 0.000
S67 Crushing injury of wrist and hand
0.497 0.503 0.000
C34.9 Bronchus or lung, unspecified
0.497 0.503 0.000
O02 Other abnormal products of conception
0.496 0.504 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.496 0.504 0.000
S61.1 Open wound of finger(s) with damage to nail
0.496 0.504 0.000
M45-M49 Spondylopathies
0.494 0.505 0.000
O16 Unspecified maternal hypertension
0.494 0.506 0.000
N10 Acute tubulo-interstitial nephritis
0.493 0.506 0.000
T98 Sequelae of other and unspecified effects of external causes
0.493 0.506 0.000
T95 Sequelae of burns, corrosions and frostbite
0.493 0.506 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.493 0.506 0.000
T91 Sequelae of injuries of neck and trunk
0.493 0.506 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.493 0.506 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.493 0.506 0.000
N60.4 Mammary duct ectasia
0.493 0.507 0.000
H91.9 Hearing loss, unspecified
0.493 0.507 0.000
N99-N99 Other disorders of the genitourinary system
0.492 0.508 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.492 0.508 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.490 0.510 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.490 0.510 0.000
S60 Superficial injury of wrist and hand
0.490 0.510 0.000
T43.2 Other and unspecified antidepressants
0.490 0.510 0.000
M24 Other specific joint derangements
0.489 0.511 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.489 0.511 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.489 0.511 0.000
T90 Sequelae of injuries of head
0.488 0.512 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.488 0.512 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.486 0.514 0.000
N42.9 Disorder of prostate, unspecified
0.485 0.515 0.000
O63.9 Long labour, unspecified
0.485 0.515 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.485 0.515 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.483 0.516 0.000
M79.8 Other specified soft tissue disorders
0.483 0.517 0.000
C50.6 Axillary tail of breast
0.482 0.518 0.000
C50.0 Nipple and areola
0.482 0.518 0.000
C18.6 Descending colon
0.482 0.518 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.481 0.519 0.000
N15 Other renal tubulo-interstitial diseases
0.481 0.519 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.481 0.519 0.000
N11 Chronic tubulo-interstitial nephritis
0.481 0.519 0.000
N64 Other disorders of breast
0.480 0.520 0.000
M15-M19 Arthrosis
0.479 0.521 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.479 0.521 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.479 0.521 0.000
T93 Sequelae of injuries of lower limb
0.478 0.521 0.000
S62 Fracture at wrist and hand level
0.478 0.522 0.000
H93 Other disorders of ear, not elsewhere classified
0.478 0.522 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.478 0.522 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.477 0.523 0.000
N46 Male infertility
0.477 0.523 0.000
N44 Torsion of testis
0.477 0.523 0.000
S65 Injury of blood vessels at wrist and hand level
0.477 0.523 0.000
H50 Other strabismus
0.476 0.524 0.000
C51-C58 Malignant neoplasms of female genital organs
0.474 0.525 0.000
C77.2 Intra-abdominal lymph nodes
0.475 0.525 0.000
M91-M94 Chondropathies
0.473 0.526 0.000
M60-M63 Disorders of muscles
0.473 0.526 0.000
M00-M03 Infectious arthropathies
0.473 0.526 0.000
T45.0 Antiallergic and antiemetic drugs
0.473 0.526 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.473 0.527 0.000
O04.9 Complete or unspecified, without complication
0.473 0.527 0.000
N48.8 Other specified disorders of penis
0.472 0.528 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.472 0.528 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.472 0.528 0.000
C32 Malignant neoplasm of larynx
0.472 0.528 0.000
C31 Malignant neoplasm of accessory sinuses
0.472 0.528 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.472 0.528 0.000
C37 Malignant neoplasm of thymus
0.472 0.528 0.000
C33 Malignant neoplasm of trachea
0.472 0.528 0.000
C18.0 Caecum
0.472 0.528 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.471 0.528 0.000
N20-N23 Urolithiasis
0.471 0.529 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.470 0.530 0.000
Y59 Other and unspecified vaccines and biological substances
0.470 0.530 0.000
Y58 Bacterial vaccines
0.470 0.530 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.470 0.530 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.470 0.530 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.470 0.530 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.470 0.530 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.470 0.530 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.470 0.530 0.000
Y48 Anaesthetics and therapeutic gases
0.470 0.530 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.470 0.530 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.470 0.530 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.470 0.530 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.470 0.530 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.469 0.531 0.000
T40.8 Lysergide [LSD]
0.469 0.531 0.000
T40.7 Cannabis (derivatives)
0.469 0.531 0.000
T40.6 Other and unspecified narcotics
0.469 0.531 0.000
T40.5 Cocaine
0.469 0.531 0.000
T40.3 Methadone
0.469 0.531 0.000
T40.1 Heroin
0.469 0.531 0.000
T40.0 Opium
0.469 0.531 0.000
O67.9 Intrapartum haemorrhage, unspecified
0.469 0.531 0.000
O72 Postpartum haemorrhage
0.469 0.531 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.467 0.533 0.000
C95 Leukaemia of unspecified cell type
0.467 0.533 0.000
C94 Other leukaemias of specified cell type
0.467 0.533 0.000
C93 Monocytic leukaemia
0.467 0.533 0.000
C88 Malignant immunoproliferative diseases
0.467 0.533 0.000
C86 Other specified types of T/NK-cell lymphoma
0.467 0.533 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.467 0.533 0.000
C81 Hodgkin's disease
0.467 0.533 0.000
C18.5 Splenic flexure
0.467 0.533 0.000
M81 Osteoporosis without pathological fracture
0.467 0.533 0.000
M79.5 Residual foreign body in soft tissue
0.467 0.533 0.000
N61 Inflammatory disorders of breast
0.466 0.534 0.000
Chapter I Certain infectious and parasitic diseases
0.465 0.535 0.000
E03 Other hypothyroidism
0.465 0.535 0.000
Q00-Q07 Congenital malformations of the nervous system
0.465 0.535 0.000
C18.7 Sigmoid colon
0.464 0.535 0.000
C77.1 Intrathoracic lymph nodes
0.465 0.535 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.464 0.536 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.464 0.536 0.000
H81 Disorders of vestibular function
0.463 0.537 0.000
D00-D09 In situ neoplasms
0.463 0.537 0.000
N13.8 Other obstructive and reflux uropathy
0.463 0.537 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.463 0.537 0.000
N13.6 Pyonephrosis
0.463 0.537 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.462 0.538 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.462 0.538 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.462 0.538 0.000
T42.3 Barbiturates
0.462 0.538 0.000
T42.2 Succinimides and oxazolidinediones
0.462 0.538 0.000
T42.1 Iminostilbenes
0.462 0.538 0.000
T42.0 Hydantoin derivatives
0.462 0.538 0.000
V10-V19 Pedal cyclist injured in transport accident
0.462 0.538 0.000
W00-W19 Falls
0.460 0.540 0.000
S68 Traumatic amputation of wrist and hand
0.460 0.540 0.000
H54 Blindness and low vision
0.460 0.540 0.000
S79 Other and unspecified injuries of hip and thigh
0.459 0.541 0.000
T65 Toxic effect of other and unspecified substances
0.458 0.541 0.000
T63 Toxic effect of contact with venomous animals
0.458 0.541 0.000
T62 Toxic effect of other noxious substances eaten as food
0.458 0.541 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.458 0.541 0.000
T60 Toxic effect of pesticides
0.458 0.541 0.000
T59 Toxic effect of other gases, fumes and vapours
0.458 0.541 0.000
T57 Toxic effect of other inorganic substances
0.458 0.541 0.000
T56 Toxic effect of metals
0.458 0.541 0.000
T54 Toxic effect of corrosive substances
0.458 0.541 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.458 0.541 0.000
T52 Toxic effect of organic solvents
0.458 0.541 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.458 0.541 0.000
T58 Toxic effect of carbon monoxide
0.458 0.541 0.000
T55 Toxic effect of soaps and detergents
0.458 0.541 0.000
N50.1 Vascular disorders of male genital organs
0.458 0.542 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.458 0.542 0.000
M35 Other systemic involvement of connective tissue
0.458 0.542 0.000
M86-M90 Other osteopathies
0.457 0.543 0.000
C50.5 Lower-outer quadrant of breast
0.457 0.543 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.457 0.543 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.457 0.543 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.457 0.543 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.457 0.543 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.457 0.543 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.457 0.543 0.000
T92.0 Sequelae of open wound of upper limb
0.457 0.543 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.457 0.543 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.456 0.543 0.000
O07 Failed attempted abortion
0.456 0.543 0.000
O06 Unspecified abortion
0.456 0.543 0.000
O05 Other abortion
0.456 0.543 0.000
O01 Hydatidiform mole
0.456 0.543 0.000
O00 Ectopic pregnancy
0.456 0.543 0.000
Y85.0 Sequelae of motor-vehicle accident
0.456 0.543 0.000
D80-D89 Certain disorders involving the immune mechanism
0.456 0.544 0.000
M18 Arthrosis of first carpometacarpal joint
0.456 0.544 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.456 0.544 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.455 0.545 0.000
S78 Traumatic amputation of hip and thigh
0.455 0.545 0.000
S77 Crushing injury of hip and thigh
0.455 0.545 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.455 0.545 0.000
S75 Injury of blood vessels at hip and thigh level
0.455 0.545 0.000
S74 Injury of nerves at hip and thigh level
0.455 0.545 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.455 0.545 0.000
S71 Open wound of hip and thigh
0.455 0.545 0.000
S70 Superficial injury of hip and thigh
0.455 0.545 0.000
Y44 Agents primarily affecting blood constituents
0.453 0.547 0.000
T51.9 Alcohol, unspecified
0.453 0.547 0.000
N60.2 Fibroadenosis of breast
0.452 0.548 0.000
N63 Unspecified lump in breast
0.451 0.549 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.450 0.550 0.000
M21 Other acquired deformities of limbs
0.450 0.550 0.000
O03 Spontaneous abortion
0.450 0.550 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.449 0.550 0.000
M23.5 Chronic instability of knee
0.449 0.550 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.449 0.551 0.000
Q80-Q89 Other congenital malformations
0.449 0.551 0.000
N60.1 Diffuse cystic mastopathy
0.449 0.551 0.000
C15.9 Oesophagus, unspecified
0.449 0.551 0.000
N42.3 Dysplasia of prostate
0.448 0.552 0.000
N42.2 Atrophy of prostate
0.448 0.552 0.000
N42.0 Calculus of prostate
0.448 0.552 0.000
H90 Conductive and sensorineural hearing loss
0.448 0.552 0.000
M25 Other joint disorders, not elsewhere classified
0.448 0.552 0.000
Y86 Sequelae of other accidents
0.448 0.552 0.000
N60.8 Other benign mammary dysplasias
0.447 0.553 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.447 0.553 0.000
H30-H36 Disorders of choroid and retina
0.445 0.555 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.445 0.555 0.000
D55-D59 Haemolytic anaemias
0.444 0.555 0.000
M85 Other disorders of bone density and structure
0.444 0.556 0.000
T14 Injury of unspecified body region
0.444 0.556 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.443 0.557 0.000
N41.0 Acute prostatitis
0.442 0.558 0.000
C80 Malignant neoplasm without specification of site
0.442 0.558 0.000
S72.0 Fracture of neck of femur
0.442 0.558 0.000
E53 Deficiency of other B group vitamins
0.442 0.558 0.000
H11 Other disorders of conjunctiva
0.441 0.559 0.000
N75 Diseases of Bartholin's gland
0.440 0.560 0.000
O15 Eclampsia
0.440 0.560 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.440 0.560 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.440 0.560 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.440 0.560 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.440 0.560 0.000
H10 Conjunctivitis
0.440 0.560 0.000
T51.0 Ethanol
0.440 0.560 0.000
N45 Orchitis and epididymitis
0.440 0.560 0.000
C18.9 Colon, unspecified
0.440 0.560 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.439 0.561 0.000
C18.8 Overlapping lesion of colon
0.439 0.561 0.000
C18.3 Hepatic flexure
0.439 0.561 0.000
C18.1 Appendix
0.439 0.561 0.000
H43 Disorders of vitreous body
0.438 0.562 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.437 0.562 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.437 0.562 0.000
T43.9 Psychotropic drug, unspecified
0.437 0.563 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.437 0.563 0.000
T43.6 Psychostimulants with abuse potential
0.437 0.563 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.437 0.563 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.437 0.563 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.437 0.563 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.437 0.563 0.000
D60-D64 Aplastic and other anaemias
0.436 0.563 0.000
Y45.0 Opioids and related analgesics
0.436 0.564 0.000
D68.8 Other specified coagulation defects
0.436 0.564 0.000
Y89 Sequelae of other external causes
0.436 0.564 0.000
Y88 Sequelae of surgical and medical care as external cause
0.436 0.564 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.436 0.564 0.000
S29 Other and unspecified injuries of thorax
0.436 0.564 0.000
S20 Superficial injury of thorax
0.435 0.564 0.000
D68.9 Coagulation defect, unspecified
0.434 0.566 0.000
N48.2 Other inflammatory disorders of penis
0.434 0.566 0.000
O82 Single delivery by Caesarean section
0.434 0.566 0.000
E04 Other non-toxic goitre
0.434 0.566 0.000
E40-E46 Malnutrition
0.433 0.567 0.000
H25 Senile cataract
0.433 0.567 0.000
D68.2 Hereditary deficiency of other clotting factors
0.432 0.568 0.000
H60-H62 Diseases of external ear
0.431 0.569 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.431 0.569 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.431 0.569 0.000
Y98 Lifestyle-related condition
0.431 0.569 0.000
Y97 Environmental-pollution-related condition
0.431 0.569 0.000
Y96 Work-related condition
0.431 0.569 0.000
S00-S09 Injuries to the head
0.431 0.569 0.000
O61.0 Failed medical induction of labour
0.430 0.570 0.000
S69.9 Unspecified injury of wrist and hand
0.430 0.570 0.000
N60.0 Solitary cyst of breast
0.430 0.570 0.000
S80 Superficial injury of lower leg
0.430 0.570 0.000
Y42.7 Androgens and anabolic congeners
0.430 0.570 0.000
N48.1 Balanoposthitis
0.429 0.571 0.000
C15.5 Lower third of oesophagus
0.429 0.571 0.000
M84 Disorders of continuity of bone
0.428 0.571 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.427 0.573 0.000
T45.8 Other primarily systemic and haematological agents
0.427 0.573 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.427 0.573 0.000
T45.6 Fibrinolysis-affecting drugs
0.427 0.573 0.000
T45.5 Anticoagulants
0.427 0.573 0.000
T45.4 Iron and its compounds
0.427 0.573 0.000
T45.3 Enzymes, not elsewhere classified
0.427 0.573 0.000
T45.2 Vitamins, not elsewhere classified
0.427 0.573 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.427 0.573 0.000
N50.0 Atrophy of testis
0.427 0.573 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.427 0.573 0.000
O97 Death from sequelae of direct obstetric causes
0.427 0.573 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.427 0.573 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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