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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118162784
log Bayes Factor = 12.6345
Chromosome 18   position 332,259  (GRCh37) Explore rs118162784 on Ensembl!
Variant rs118162784 is part of Cluster X0249

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
S00-S09 Injuries to the head
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.996 0.004 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.995 0.005 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.992 0.008 0.000
B95-B98 Bacterial, viral and other infectious agents
0.990 0.010 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.986 0.014 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.982 0.018 0.000
Chapter XX External causes of morbidity and mortality
0.980 0.020 0.000
T81 Complications of procedures, not elsewhere classified
0.979 0.021 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.975 0.025 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.973 0.027 0.000
I35 Nonrheumatic aortic valve disorders
0.972 0.028 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.971 0.029 0.000
C78.0 Secondary malignant neoplasm of lung
0.966 0.034 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.961 0.039 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.961 0.039 0.000
Chapter V Mental and behavioural disorders
0.958 0.042 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.954 0.046 0.000
I49 Other cardiac arrhythmias
0.951 0.049 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.941 0.059 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.938 0.062 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.936 0.064 0.000
S01 Open wound of head
0.936 0.064 0.000
I45 Other conduction disorders
0.935 0.065 0.000
C15-C26 Malignant neoplasms of digestive organs
0.932 0.068 0.000
S02 Fracture of skull and facial bones
0.929 0.071 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.918 0.082 0.000
F30-F39 Mood [affective] disorders
0.917 0.083 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.915 0.085 0.000
L03 Cellulitis
0.912 0.088 0.000
I35.0 Aortic (valve) stenosis
0.910 0.090 0.000
C78.2 Secondary malignant neoplasm of pleura
0.910 0.090 0.000
L50-L54 Urticaria and erythema
0.908 0.092 0.000
I42 Cardiomyopathy
0.905 0.095 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.904 0.096 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.904 0.096 0.000
S09 Other and unspecified injuries of head
0.902 0.098 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.901 0.099 0.000
S70-S79 Injuries to the hip and thigh
0.900 0.100 0.000
I80 Phlebitis and thrombophlebitis
0.899 0.101 0.000
S00 Superficial injury of head
0.892 0.108 0.000
Y83.6 Removal of other organ (partial) (total)
0.891 0.109 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.890 0.110 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.885 0.115 0.000
F32 Depressive episode
0.885 0.115 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.884 0.116 0.000
I84 Haemorrhoids
0.881 0.119 0.000
L60-L75 Disorders of skin appendages
0.881 0.119 0.000
I45.1 Other and unspecified right bundle-branch block
0.879 0.121 0.000
D60-D64 Aplastic and other anaemias
0.878 0.122 0.000
S40-S49 Injuries to the shoulder and upper arm
0.877 0.123 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.873 0.127 0.000
Y83.8 Other surgical procedures
0.873 0.127 0.000
L03.1 Cellulitis of other parts of limb
0.869 0.131 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.868 0.132 0.000
S80-S89 Injuries to the knee and lower leg
0.867 0.133 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.866 0.134 0.000
S06 Intracranial injury
0.866 0.134 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.863 0.137 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.860 0.140 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.859 0.141 0.000
B25-B34 Other viral diseases
0.857 0.143 0.000
S50-S59 Injuries to the elbow and forearm
0.850 0.150 0.000
S01.8 Open wound of other parts of head
0.848 0.152 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.845 0.155 0.000
C77.2 Intra-abdominal lymph nodes
0.844 0.156 0.000
C51-C58 Malignant neoplasms of female genital organs
0.844 0.156 0.000
I50 Heart failure
0.842 0.158 0.000
S09.9 Unspecified injury of head
0.834 0.166 0.000
I49.3 Ventricular premature depolarisation
0.833 0.167 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.832 0.168 0.000
Y43 Primarily systemic agents
0.832 0.168 0.000
S00.8 Superficial injury of other parts of head
0.832 0.168 0.000
I35.1 Aortic (valve) insufficiency
0.831 0.169 0.000
D50-D53 Nutritional anaemias
0.830 0.170 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.828 0.172 0.000
I89.0 Lymphoedema, not elsewhere classified
0.825 0.175 0.000
T81.9 Unspecified complication of procedure
0.823 0.177 0.000
T86 Failure and rejection of transplanted organs and tissues
0.822 0.178 0.000
F32.9 Depressive episode, unspecified
0.818 0.182 0.000
D64 Other anaemias
0.815 0.185 0.000
I49.1 Atrial premature depolarisation
0.812 0.188 0.000
C20 Malignant neoplasm of rectum
0.811 0.189 0.000
L03.3 Cellulitis of trunk
0.810 0.190 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.807 0.193 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.807 0.193 0.000
I38 Endocarditis, valve unspecified
0.804 0.196 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.801 0.199 0.000
S10-S19 Injuries to the neck
0.799 0.201 0.000
Chapter XXII Codes for special purposes
0.799 0.201 0.000
S02.0 Fracture of vault of skull
0.799 0.201 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.798 0.202 0.000
L20-L30 Dermatitis and eczema
0.798 0.202 0.000
S60-S69 Injuries to the wrist and hand
0.797 0.203 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.797 0.203 0.000
L50 Urticaria
0.796 0.204 0.000
L40-L45 Papulosquamous disorders
0.795 0.204 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.795 0.205 0.000
S02.1 Fracture of base of skull
0.794 0.206 0.000
S90-S99 Injuries to the ankle and foot
0.788 0.212 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.787 0.213 0.000
C79 Secondary malignant neoplasm of other sites
0.786 0.214 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.786 0.214 0.000
I50.1 Left ventricular failure
0.785 0.215 0.000
I37 Pulmonary valve disorders
0.784 0.216 0.000
S40 Superficial injury of shoulder and upper arm
0.783 0.217 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.781 0.219 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.781 0.219 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.778 0.222 0.000
I84.6 Residual haemorrhoidal skin tags
0.778 0.222 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.777 0.223 0.000
C56 Malignant neoplasm of ovary
0.777 0.223 0.000
I84.8 Unspecified haemorrhoids with other complications
0.776 0.224 0.000
F32.1 Moderate depressive episode
0.773 0.227 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.773 0.227 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.772 0.228 0.000
D64.9 Anaemia, unspecified
0.771 0.229 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.770 0.230 0.000
E70-E90 Metabolic disorders
0.768 0.232 0.000
L53 Other erythematous conditions
0.768 0.232 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.767 0.233 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.766 0.234 0.000
S01.2 Open wound of nose
0.766 0.234 0.000
V40-V49 Car occupant injured in transport accident
0.765 0.235 0.000
T79-T79 Certain early complications of trauma
0.763 0.237 0.000
I36 Nonrheumatic tricuspid valve disorders
0.763 0.237 0.000
I84.4 External haemorrhoids with other complications
0.761 0.239 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.760 0.240 0.000
B34 Viral infection of unspecified site
0.757 0.243 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.756 0.244 0.000
S72 Fracture of femur
0.756 0.244 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.755 0.245 0.000
X50-X57 Overexertion, travel and privation
0.754 0.245 0.000
D69 Purpura and other haemorrhagic conditions
0.754 0.246 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.753 0.247 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.752 0.248 0.000
Y43.3 Other antineoplastic drugs
0.752 0.248 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.750 0.250 0.000
I42.0 Dilated cardiomyopathy
0.749 0.251 0.000
T51 Toxic effect of alcohol
0.748 0.252 0.000
C18 Malignant neoplasm of colon
0.746 0.254 0.000
L08 Other local infections of skin and subcutaneous tissue
0.746 0.254 0.000
D00-D09 In situ neoplasms
0.745 0.255 0.000
I49.0 Ventricular fibrillation and flutter
0.744 0.256 0.000
I35.9 Aortic valve disorder, unspecified
0.744 0.256 0.000
T82.3 Mechanical complication of other vascular grafts
0.743 0.256 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.742 0.258 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.742 0.258 0.000
A30-A49 Other bacterial diseases
0.741 0.259 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.740 0.260 0.000
Chapter VIII Diseases of the ear and mastoid process
0.738 0.262 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.738 0.262 0.000
D80-D89 Certain disorders involving the immune mechanism
0.738 0.262 0.000
S20-S29 Injuries to the thorax
0.736 0.264 0.000
C17 Malignant neoplasm of small intestine
0.734 0.266 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.733 0.267 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.733 0.267 0.000
S01.5 Open wound of lip and oral cavity
0.732 0.268 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.730 0.270 0.000
I71 Aortic aneurysm and dissection
0.730 0.270 0.000
I86 Varicose veins of other sites
0.729 0.270 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.729 0.271 0.000
S00.0 Superficial injury of scalp
0.727 0.273 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.724 0.276 0.000
F99-F99 Unspecified mental disorder
0.724 0.276 0.000
I49.8 Other specified cardiac arrhythmias
0.724 0.276 0.000
I87 Other disorders of veins
0.723 0.277 0.000
S02.5 Fracture of tooth
0.723 0.277 0.000
D55-D59 Haemolytic anaemias
0.722 0.278 0.000
Y48 Anaesthetics and therapeutic gases
0.721 0.279 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.721 0.279 0.000
I33 Acute and subacute endocarditis
0.721 0.279 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.720 0.280 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.720 0.280 0.000
C25 Malignant neoplasm of pancreas
0.719 0.281 0.000
S82 Fracture of lower leg, including ankle
0.719 0.281 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.717 0.283 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
L50.9 Urticaria, unspecified
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
S08 Traumatic amputation of part of head
0.716 0.284 0.000
S07 Crushing injury of head
0.716 0.284 0.000
S05 Injury of eye and orbit
0.716 0.284 0.000
S04 Injury of cranial nerves
0.716 0.284 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.716 0.284 0.000
S68 Traumatic amputation of wrist and hand
0.714 0.286 0.000
B99-B99 Other infectious diseases
0.714 0.286 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B65-B83 Helminthiases
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
C77.3 Axillary and upper limb lymph nodes
0.714 0.286 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.713 0.286 0.000
Y83.3 Surgical operation with formation of external stoma
0.713 0.287 0.000
F60-F69 Disorders of adult personality and behaviour
0.713 0.287 0.000
L72.0 Epidermal cyst
0.713 0.287 0.000
I49.5 Sick sinus syndrome
0.712 0.288 0.000
L10-L14 Bullous disorders
0.711 0.289 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.710 0.289 0.000
F80-F89 Disorders of psychological development
0.710 0.290 0.000
S01.0 Open wound of scalp
0.708 0.292 0.000
I84.5 External haemorrhoids without complication
0.708 0.292 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.707 0.293 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.707 0.293 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.707 0.293 0.000
X60-X84 Intentional self-harm
0.707 0.293 0.000
I44 Atrioventricular and left bundle-branch block
0.707 0.293 0.000
S71 Open wound of hip and thigh
0.707 0.293 0.000
I42.2 Other hypertrophic cardiomyopathy
0.706 0.294 0.000
S02.00 Fracture of vault of skull (closed)
0.706 0.294 0.000
S79 Other and unspecified injuries of hip and thigh
0.706 0.294 0.000
C73 Malignant neoplasm of thyroid gland
0.705 0.295 0.000
Y83.9 Surgical procedure, unspecified
0.705 0.295 0.000
I46 Cardiac arrest
0.704 0.296 0.000
I88 Nonspecific lymphadenitis
0.704 0.296 0.000
I81 Portal vein thrombosis
0.704 0.296 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.704 0.296 0.000
Q60-Q64 Congenital malformations of the urinary system
0.704 0.296 0.000
C16 Malignant neoplasm of stomach
0.703 0.297 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.703 0.297 0.000
I84.3 External thrombosed haemorrhoids
0.702 0.298 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.702 0.298 0.000
Y35-Y36 Legal intervention and operations of war
0.702 0.298 0.000
Y10-Y34 Event of undetermined intent
0.702 0.298 0.000
Y00-Y09 Assault
0.702 0.298 0.000
X85-X99 Assault
0.702 0.298 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.702 0.298 0.000
X30-X39 Exposure to forces of nature
0.702 0.298 0.000
X20-X29 Contact with venomous animals and plants
0.702 0.298 0.000
X10-X19 Contact with heat and hot substances
0.702 0.298 0.000
X00-X09 Exposure to smoke, fire and flames
0.702 0.298 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.702 0.298 0.000
W75-W84 Other accidental threats to breathing
0.702 0.298 0.000
W65-W74 Accidental drowning and submersion
0.702 0.298 0.000
W50-W64 Exposure to animate mechanical forces
0.702 0.298 0.000
V98-V99 Other and unspecified transport accidents
0.702 0.298 0.000
V95-V97 Air and space transport accidents
0.702 0.298 0.000
V90-V94 Water transport accidents
0.702 0.298 0.000
V80-V89 Other land transport accidents
0.702 0.298 0.000
V70-V79 Bus occupant injured in transport accident
0.702 0.298 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.702 0.298 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.702 0.298 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.702 0.298 0.000
V01-V09 Pedestrian injured in transport accident
0.702 0.298 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.702 0.298 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.702 0.298 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.702 0.298 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.702 0.298 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.701 0.299 0.000
I45.6 Preexcitation syndrome
0.701 0.299 0.000
L43 Lichen planus
0.701 0.299 0.000
C77.4 Inguinal and lower limb lymph nodes
0.701 0.299 0.000
S51 Open wound of forearm
0.700 0.300 0.000
C81 Hodgkin's disease
0.700 0.300 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.700 0.300 0.000
I82 Other venous embolism and thrombosis
0.700 0.300 0.000
S01.1 Open wound of eyelid and periocular area
0.699 0.301 0.000
S02.10 Fracture of base of skull (closed)
0.698 0.302 0.000
I42.8 Other cardiomyopathies
0.698 0.302 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.698 0.302 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.698 0.302 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.698 0.302 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.698 0.302 0.000
S06.4 Epidural haemorrhage
0.697 0.303 0.000
I35.8 Other aortic valve disorders
0.696 0.303 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.696 0.304 0.000
B35-B49 Mycoses
0.696 0.304 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.696 0.304 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.696 0.304 0.000
S40.0 Contusion of shoulder and upper arm
0.696 0.304 0.000
I73 Other peripheral vascular diseases
0.696 0.304 0.000
C91 Lymphoid leukaemia
0.695 0.305 0.000
I45.5 Other specified heart block
0.695 0.305 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.694 0.306 0.000
T59 Toxic effect of other gases, fumes and vapours
0.694 0.306 0.000
D68 Other coagulation defects
0.693 0.307 0.000
D61 Other aplastic anaemias
0.693 0.307 0.000
D51 Vitamin B12 deficiency anaemia
0.693 0.307 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.692 0.308 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.692 0.308 0.000
I49.9 Cardiac arrhythmia, unspecified
0.692 0.308 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.692 0.308 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.691 0.309 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.691 0.309 0.000
I85 Oesophageal varices
0.690 0.310 0.000
I10-I15 Hypertensive diseases
0.690 0.310 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.687 0.313 0.000
F70-F79 Mental retardation
0.687 0.313 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.687 0.313 0.000
C18.2 Ascending colon
0.686 0.314 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.686 0.314 0.000
C88 Malignant immunoproliferative diseases
0.686 0.314 0.000
B34.9 Viral infection, unspecified
0.685 0.315 0.000
T66-T78 Other and unspecified effects of external causes
0.685 0.315 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.685 0.315 0.000
S70 Superficial injury of hip and thigh
0.683 0.317 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.683 0.317 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.682 0.318 0.000
I49.2 Junctional premature depolarisation
0.682 0.318 0.000
D53 Other nutritional anaemias
0.682 0.318 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.681 0.319 0.000
V10-V19 Pedal cyclist injured in transport accident
0.680 0.319 0.000
B15-B19 Viral hepatitis
0.680 0.320 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.680 0.320 0.000
Y57 Other and unspecified drugs and medicaments
0.679 0.320 0.000
Y52 Agents primarily affecting the cardiovascular system
0.679 0.321 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.679 0.321 0.000
F43 Reaction to severe stress, and adjustment disorders
0.678 0.322 0.000
S41 Open wound of shoulder and upper arm
0.677 0.322 0.000
L27 Dermatitis due to substances taken internally
0.677 0.323 0.000
Y83.0 Surgical operation with transplant of whole organ
0.676 0.323 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.676 0.324 0.000
S06.0 Concussion
0.676 0.324 0.000
I49.4 Other and unspecified premature depolarisation
0.675 0.325 0.000
Y83.5 Amputation of limb(s)
0.675 0.325 0.000
C15 Malignant neoplasm of oesophagus
0.675 0.325 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.674 0.326 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.673 0.327 0.000
L04 Acute lymphadenitis
0.672 0.328 0.000
L01 Impetigo
0.672 0.328 0.000
L00 Staphylococcal scalded skin syndrome
0.672 0.328 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.672 0.328 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.672 0.328 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.671 0.328 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.671 0.329 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.671 0.329 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.671 0.329 0.000
S01.7 Multiple open wounds of head
0.671 0.329 0.000
S01.4 Open wound of cheek and temporomandibular area
0.671 0.329 0.000
I45.9 Conduction disorder, unspecified
0.670 0.329 0.000
I45.8 Other specified conduction disorders
0.670 0.329 0.000
I45.4 Nonspecific intraventricular block
0.670 0.329 0.000
I45.3 Trifascicular block
0.670 0.329 0.000
I45.2 Bifascicular block
0.670 0.329 0.000
I45.0 Right fascicular block
0.670 0.329 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.670 0.330 0.000
S81 Open wound of lower leg
0.670 0.330 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.669 0.331 0.000
S90 Superficial injury of ankle and foot
0.669 0.331 0.000
F31 Bipolar affective disorder
0.669 0.331 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.668 0.332 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.668 0.332 0.000
C21 Malignant neoplasm of anus and anal canal
0.668 0.332 0.000
C23 Malignant neoplasm of gallbladder
0.668 0.332 0.000
L03.2 Cellulitis of face
0.668 0.332 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.668 0.332 0.000
C92 Myeloid leukaemia
0.668 0.332 0.000
L53.9 Erythematous condition, unspecified
0.667 0.333 0.000
S86 Injury of muscle and tendon at lower leg level
0.667 0.333 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.667 0.333 0.000
F33 Recurrent depressive disorder
0.666 0.334 0.000
S02.8 Fractures of other skull and facial bones
0.666 0.334 0.000
S02.7 Multiple fractures involving skull and facial bones
0.666 0.334 0.000
S02.6 Fracture of mandible
0.666 0.334 0.000
S02.3 Fracture of orbital floor
0.666 0.334 0.000
Q80-Q89 Other congenital malformations
0.665 0.335 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.664 0.336 0.000
L73 Other follicular disorders
0.664 0.336 0.000
S02.2 Fracture of nasal bones
0.663 0.336 0.000
L03.9 Cellulitis, unspecified
0.663 0.337 0.000
V20-V29 Motorcycle rider injured in transport accident
0.662 0.337 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.661 0.338 0.000
L71 Rosacea
0.661 0.339 0.000
D69.6 Thrombocytopenia, unspecified
0.660 0.340 0.000
C80 Malignant neoplasm without specification of site
0.660 0.340 0.000
S72.0 Fracture of neck of femur
0.659 0.341 0.000
D62 Acute posthaemorrhagic anaemia
0.659 0.341 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.658 0.341 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.658 0.341 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.658 0.341 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.658 0.341 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.658 0.341 0.000
L03.8 Cellulitis of other sites
0.658 0.342 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.658 0.342 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.658 0.342 0.000
F38 Other mood [affective] disorders
0.657 0.343 0.000
F34 Persistent mood [affective] disorders
0.657 0.343 0.000
F30 Manic episode
0.657 0.343 0.000
F39 Unspecified mood [affective] disorder
0.657 0.343 0.000
Y43.4 Immunosuppressive agents
0.657 0.343 0.000
F03 Unspecified dementia
0.657 0.343 0.000
Y59 Other and unspecified vaccines and biological substances
0.656 0.344 0.000
Y58 Bacterial vaccines
0.656 0.344 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.656 0.344 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.656 0.344 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.656 0.344 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.656 0.344 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.656 0.344 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.656 0.344 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.656 0.344 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.656 0.344 0.000
Y44 Agents primarily affecting blood constituents
0.656 0.344 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.655 0.345 0.000
S50 Superficial injury of forearm
0.655 0.345 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.655 0.345 0.000
L54 Erythema in diseases classified elsewhere
0.651 0.349 0.000
L51 Erythema multiforme
0.651 0.349 0.000
L52 Erythema nodosum
0.651 0.349 0.000
Y40 Systemic antibiotics
0.649 0.351 0.000
E87.5 Hyperkalaemia
0.649 0.351 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.649 0.351 0.000
I42.6 Alcoholic cardiomyopathy
0.649 0.351 0.000
I42.5 Other restrictive cardiomyopathy
0.649 0.351 0.000
I42.4 Endocardial fibroelastosis
0.649 0.351 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.649 0.351 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.649 0.351 0.000
S09.8 Other specified injuries of head
0.647 0.353 0.000
S09.7 Multiple injuries of head
0.647 0.353 0.000
S09.2 Traumatic rupture of ear drum
0.647 0.353 0.000
S09.1 Injury of muscle and tendon of head
0.647 0.353 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.647 0.353 0.000
S01.9 Open wound of head, part unspecified
0.647 0.353 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.646 0.354 0.000
F40 Phobic anxiety disorders
0.646 0.354 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.646 0.354 0.000
I89.1 Lymphangitis
0.646 0.354 0.000
S78 Traumatic amputation of hip and thigh
0.645 0.354 0.000
S77 Crushing injury of hip and thigh
0.645 0.354 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.645 0.354 0.000
S75 Injury of blood vessels at hip and thigh level
0.645 0.354 0.000
S74 Injury of nerves at hip and thigh level
0.645 0.354 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.645 0.354 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.645 0.355 0.000
I31 Other diseases of pericardium
0.644 0.356 0.000
S00.3 Superficial injury of nose
0.644 0.356 0.000
S19 Other and unspecified injuries of neck
0.642 0.358 0.000
Q50-Q56 Congenital malformations of genital organs
0.641 0.359 0.000
B07 Viral warts
0.641 0.359 0.000
S00.7 Multiple superficial injuries of head
0.639 0.360 0.000
S00.5 Superficial injury of lip and oral cavity
0.639 0.360 0.000
S00.4 Superficial injury of ear
0.639 0.360 0.000
W20-W49 Exposure to inanimate mechanical forces
0.639 0.361 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.638 0.362 0.000
Q35-Q37 Cleft lip and cleft palate
0.638 0.362 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.638 0.362 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.638 0.362 0.000
Q00-Q07 Congenital malformations of the nervous system
0.638 0.362 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.638 0.362 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.638 0.362 0.000
D52 Folate deficiency anaemia
0.637 0.363 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.637 0.363 0.000
S52 Fracture of forearm
0.637 0.363 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.636 0.363 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.635 0.365 0.000
I77 Other disorders of arteries and arterioles
0.635 0.365 0.000
F32.8 Other depressive episodes
0.634 0.366 0.000
F32.0 Mild depressive episode
0.634 0.366 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.634 0.366 0.000
C95 Leukaemia of unspecified cell type
0.634 0.366 0.000
C94 Other leukaemias of specified cell type
0.634 0.366 0.000
C93 Monocytic leukaemia
0.634 0.366 0.000
C86 Other specified types of T/NK-cell lymphoma
0.634 0.366 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.634 0.366 0.000
A00-A09 Intestinal infectious diseases
0.633 0.367 0.000
C77.8 Lymph nodes of multiple regions
0.633 0.367 0.000
I42.9 Cardiomyopathy, unspecified
0.632 0.368 0.000
I84.0 Internal thrombosed haemorrhoids
0.632 0.368 0.000
L75 Apocrine sweat disorders
0.631 0.369 0.000
L74 Eccrine sweat disorders
0.631 0.369 0.000
L70 Acne
0.631 0.369 0.000
L68 Hypertrichosis
0.631 0.369 0.000
L67 Hair colour and hair shaft abnormalities
0.631 0.369 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.631 0.369 0.000
L65 Other nonscarring hair loss
0.631 0.369 0.000
L64 Androgenic alopecia
0.631 0.369 0.000
L63 Alopecia areata
0.631 0.369 0.000
L62 Nail disorders in diseases classified elsewhere
0.631 0.369 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.630 0.370 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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