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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12019358
log Bayes Factor = 0.088972
Chromosome 7   position 41,275,504  (GRCh37) Explore rs12019358 on Ensembl!
Variant rs12019358 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.911 0.089
I10-I15 Hypertensive diseases
0.000 0.928 0.072
I30-I52 Other forms of heart disease
0.000 0.932 0.068
I35 Nonrheumatic aortic valve disorders
0.000 0.933 0.067
Chapter IX Diseases of the circulatory system
0.000 0.935 0.065
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.935 0.065
I47 Paroxysmal tachycardia
0.000 0.939 0.061
I25 Chronic ischaemic heart disease
0.000 0.939 0.061
I35.0 Aortic (valve) stenosis
0.000 0.939 0.061
I20-I25 Ischaemic heart diseases
0.000 0.939 0.061
I35.1 Aortic (valve) insufficiency
0.000 0.939 0.061
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.060 0.940 0.000
I47.2 Ventricular tachycardia
0.000 0.941 0.059
I46 Cardiac arrest
0.000 0.942 0.058
I49 Other cardiac arrhythmias
0.000 0.943 0.057
C77.2 Intra-abdominal lymph nodes
0.056 0.944 0.000
I38 Endocarditis, valve unspecified
0.000 0.944 0.056
I31 Other diseases of pericardium
0.000 0.944 0.056
I45 Other conduction disorders
0.000 0.945 0.055
C77.0 Lymph nodes of head, face and neck
0.055 0.945 0.000
C77.9 Lymph node, unspecified
0.054 0.946 0.000
C77.3 Axillary and upper limb lymph nodes
0.054 0.946 0.000
I34 Nonrheumatic mitral valve disorders
0.000 0.947 0.053
I25.1 Atherosclerotic heart disease
0.000 0.948 0.052
I15 Secondary hypertension
0.000 0.948 0.052
I13 Hypertensive heart and renal disease
0.000 0.948 0.052
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.949 0.051
C77.4 Inguinal and lower limb lymph nodes
0.050 0.950 0.000
I46.0 Cardiac arrest with successful resuscitation
0.000 0.950 0.050
I05-I09 Chronic rheumatic heart diseases
0.000 0.951 0.049
I49.3 Ventricular premature depolarisation
0.000 0.951 0.049
I52 Other heart disorders in diseases classified elsewhere
0.000 0.951 0.049
I48 Atrial fibrillation and flutter
0.000 0.951 0.049
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.951 0.049
I41 Myocarditis in diseases classified elsewhere
0.000 0.951 0.049
I40 Acute myocarditis
0.000 0.951 0.049
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.951 0.049
I37 Pulmonary valve disorders
0.000 0.951 0.049
I33 Acute and subacute endocarditis
0.000 0.951 0.049
I32 Pericarditis in diseases classified elsewhere
0.000 0.951 0.049
I30 Acute pericarditis
0.000 0.951 0.049
I11 Hypertensive heart disease
0.000 0.951 0.049
I44 Atrioventricular and left bundle-branch block
0.000 0.951 0.049
I35.9 Aortic valve disorder, unspecified
0.000 0.952 0.048
I35.8 Other aortic valve disorders
0.000 0.952 0.048
C77.5 Intrapelvic lymph nodes
0.047 0.953 0.000
I00-I02 Acute rheumatic fever
0.000 0.953 0.047
I49.0 Ventricular fibrillation and flutter
0.000 0.953 0.047
C50 Malignant neoplasm of breast
0.047 0.953 0.000
I45.1 Other and unspecified right bundle-branch block
0.000 0.954 0.046
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.046 0.954 0.000
I31.3 Pericardial effusion (noninflammatory)
0.000 0.954 0.046
C50.9 Breast, unspecified
0.045 0.955 0.000
I47.0 Reentry ventricular arrhythmia
0.000 0.956 0.044
I25.6 Silent myocardial ischaemia
0.000 0.956 0.044
I25.5 Ischaemic cardiomyopathy
0.000 0.956 0.044
I25.4 Coronary artery aneurysm
0.000 0.956 0.044
I25.3 Aneurysm of heart
0.000 0.956 0.044
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.956 0.044
C50-C50 Malignant neoplasm of breast
0.044 0.956 0.000
I36 Nonrheumatic tricuspid valve disorders
0.000 0.956 0.044
I23 Certain current complications following acute myocardial infarction
0.000 0.956 0.044
I20 Angina pectoris
0.000 0.956 0.044
I51 Complications and ill-defined descriptions of heart disease
0.000 0.956 0.044
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.044 0.956 0.000
C77.8 Lymph nodes of multiple regions
0.043 0.956 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.957 0.043
I34.0 Mitral (valve) insufficiency
0.000 0.957 0.043
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.043 0.957 0.000
I49.9 Cardiac arrhythmia, unspecified
0.000 0.957 0.043
I24 Other acute ischaemic heart diseases
0.000 0.957 0.042
Chapter II Neoplasms
0.042 0.958 0.000
I12 Hypertensive renal disease
0.000 0.958 0.042
I47.1 Supraventricular tachycardia
0.000 0.958 0.042
I31.9 Disease of pericardium, unspecified
0.000 0.958 0.042
I46.1 Sudden cardiac death, so described
0.000 0.958 0.042
I46.9 Cardiac arrest, unspecified
0.000 0.959 0.041
I22 Subsequent myocardial infarction
0.000 0.959 0.041
I60-I69 Cerebrovascular diseases
0.000 0.959 0.041
I49.4 Other and unspecified premature depolarisation
0.000 0.959 0.041
I49.2 Junctional premature depolarisation
0.000 0.959 0.041
I49.1 Atrial premature depolarisation
0.000 0.959 0.041
C77.1 Intrathoracic lymph nodes
0.041 0.959 0.000
C85.1 B-cell lymphoma, unspecified
0.041 0.959 0.000
C50.2 Upper-inner quadrant of breast
0.041 0.959 0.000
I45.6 Preexcitation syndrome
0.000 0.959 0.041
I31.8 Other specified diseases of pericardium
0.000 0.960 0.040
I31.2 Haemopericardium, not elsewhere classified
0.000 0.960 0.040
I31.1 Chronic constrictive pericarditis
0.000 0.960 0.040
I31.0 Chronic adhesive pericarditis
0.000 0.960 0.040
I45.9 Conduction disorder, unspecified
0.000 0.960 0.039
I45.8 Other specified conduction disorders
0.000 0.960 0.039
I45.4 Nonspecific intraventricular block
0.000 0.960 0.039
I45.3 Trifascicular block
0.000 0.960 0.039
I45.2 Bifascicular block
0.000 0.960 0.039
I45.0 Right fascicular block
0.000 0.960 0.039
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.960 0.039
I25.2 Old myocardial infarction
0.000 0.961 0.039
I08 Multiple valve diseases
0.000 0.961 0.038
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.962 0.038
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.962 0.038
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.962 0.038
C50.0 Nipple and areola
0.038 0.962 0.000
I42 Cardiomyopathy
0.000 0.962 0.038
I49.5 Sick sinus syndrome
0.000 0.962 0.038
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.038 0.962 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.962 0.037
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.962 0.037
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.962 0.037
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.962 0.037
I15.9 Seconday hypertension, unspecified
0.000 0.962 0.037
I15.8 Other secondary hypertension
0.000 0.962 0.037
I15.2 Hypertension secondary to endocrine disorders
0.000 0.962 0.037
I15.1 Hypertension secondary to other renal disorders
0.000 0.962 0.037
I15.0 Renovascular hypertension
0.000 0.962 0.037
I20.0 Unstable angina
0.000 0.963 0.037
C90 Multiple myeloma and malignant plasma cell neoplasms
0.037 0.963 0.000
I44.1 Atrioventricular block, second degree
0.000 0.963 0.037
I69 Sequelae of cerebrovascular disease
0.000 0.963 0.037
C50.4 Upper-outer quadrant of breast
0.036 0.964 0.000
I45.5 Other specified heart block
0.000 0.964 0.036
I34.1 Mitral (valve) prolapse
0.000 0.964 0.036
C15-C26 Malignant neoplasms of digestive organs
0.036 0.964 0.000
I44.0 Atrioventricular block, first degree
0.000 0.964 0.036
C50.5 Lower-outer quadrant of breast
0.036 0.964 0.000
I09 Other rheumatic heart diseases
0.000 0.964 0.035
I06 Rheumatic aortic valve diseases
0.000 0.964 0.035
I05 Rheumatic mitral valve diseases
0.000 0.964 0.035
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.036 0.964 0.000
I30.9 Acute pericarditis, unspecified
0.000 0.964 0.035
I30.8 Other forms of acute pericarditis
0.000 0.964 0.035
I30.1 Infective pericarditis
0.000 0.964 0.035
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.964 0.035
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.964 0.035
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.964 0.035
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.964 0.035
I33.9 Acute endocarditis, unspecified
0.000 0.964 0.035
I33.0 Acute and subacute infective endocarditis
0.000 0.964 0.035
I37.9 Pulmonary valve disorder, unspecified
0.000 0.964 0.035
I37.8 Other pulmonary valve disorders
0.000 0.964 0.035
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.964 0.035
I37.1 Pulmonary valve insufficiency
0.000 0.964 0.035
I37.0 Pulmonary valve stenosis
0.000 0.964 0.035
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.964 0.035
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.964 0.035
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.964 0.035
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.964 0.035
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.964 0.035
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.964 0.035
I40.9 Acute myocarditis, unspecified
0.000 0.964 0.035
I40.8 Other acute myocarditis
0.000 0.964 0.035
I40.1 Isolated myocarditis
0.000 0.964 0.035
I40.0 Infective myocarditis
0.000 0.964 0.035
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.964 0.035
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.964 0.035
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.964 0.035
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.964 0.035
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.964 0.035
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.964 0.035
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.964 0.035
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.964 0.035
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.964 0.035
I48.4 Atypical atrial flutter
0.000 0.964 0.035
I48.3 Typical atrial flutter
0.000 0.964 0.035
I48.2 Chronic atrial fibrillation
0.000 0.964 0.035
I48.1 Persistent atrial fibrillation
0.000 0.964 0.035
I48.0 Paroxysmal atrial fibrillation
0.000 0.964 0.035
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.964 0.035
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.964 0.035
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.964 0.035
C50.8 Overlapping lesion of breast
0.035 0.964 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.965 0.035
I44.6 Other and unspecified fascicular block
0.000 0.965 0.035
I44.5 Left posterior fascicular block
0.000 0.965 0.035
I44.4 Left anterior fascicular block
0.000 0.965 0.035
I44.3 Other and unspecified atrioventricular block
0.000 0.965 0.035
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.965 0.035
I07 Rheumatic tricuspid valve diseases
0.000 0.965 0.035
I27 Other pulmonary heart diseases
0.000 0.965 0.035
I51.7 Cardiomegaly
0.000 0.965 0.035
I49.8 Other specified cardiac arrhythmias
0.000 0.965 0.034
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.965 0.034
I44.2 Atrioventricular block, complete
0.000 0.966 0.034
C50.3 Lower-inner quadrant of breast
0.034 0.966 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.034 0.966 0.000
I02 Rheumatic chorea
0.000 0.966 0.034
I01 Rheumatic fever with heart involvement
0.000 0.966 0.034
I00 Rheumatic fever without mention of heart involvement
0.000 0.966 0.034
C50.6 Axillary tail of breast
0.034 0.966 0.000
C25 Malignant neoplasm of pancreas
0.033 0.967 0.000
I44.7 Left bundle-branch block, unspecified
0.000 0.967 0.033
C81 Hodgkin's disease
0.033 0.967 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.033 0.967 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.967 0.033
C90.0 Multiple myeloma
0.033 0.967 0.000
I20.8 Other forms of angina pectoris
0.000 0.967 0.033
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.968 0.032
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.968 0.032
I21 Acute myocardial infarction
0.000 0.968 0.032
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.968 0.032
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.968 0.032
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.968 0.032
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.968 0.032
I23.8 Other current complications following acute myocardial infarction
0.000 0.968 0.032
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.968 0.032
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.968 0.032
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.968 0.032
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.968 0.032
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.968 0.032
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.968 0.032
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.968 0.032
C18 Malignant neoplasm of colon
0.032 0.968 0.000
I51.6 Cardiovascular disease, unspecified
0.000 0.968 0.031
I51.5 Myocardial degeneration
0.000 0.968 0.031
I51.4 Myocarditis, unspecified
0.000 0.968 0.031
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.968 0.031
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.968 0.031
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.968 0.031
I51.0 Cardiac septal defect, acquired
0.000 0.968 0.031
C83 Diffuse non-Hodgkin's lymphoma
0.032 0.968 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.031 0.968 0.000
C95 Leukaemia of unspecified cell type
0.031 0.968 0.000
C94 Other leukaemias of specified cell type
0.031 0.968 0.000
C93 Monocytic leukaemia
0.031 0.968 0.000
C88 Malignant immunoproliferative diseases
0.031 0.968 0.000
C86 Other specified types of T/NK-cell lymphoma
0.031 0.968 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.031 0.968 0.000
I28 Other diseases of pulmonary vessels
0.000 0.969 0.031
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.031 0.969 0.000
I62 Other nontraumatic intracranial haemorrhage
0.000 0.969 0.031
C85.7 Other specified types of non-Hodgkin's lymphoma
0.031 0.969 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.031 0.969 0.000
C85.0 Lymphosarcoma
0.031 0.969 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.031 0.969 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.031 0.969 0.000
I24.1 Dressler's syndrome
0.000 0.969 0.031
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.031 0.969 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.031 0.969 0.000
I08.0 Disorders of both mitral and aortic valves
0.000 0.969 0.030
C50.1 Central portion of breast
0.030 0.969 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.030 0.970 0.000
C92 Myeloid leukaemia
0.030 0.970 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.030 0.970 0.000
I24.8 Other forms of acute ischaemic heart disease
0.000 0.970 0.030
I22.8 Subsequent myocardial infarction of other sites
0.000 0.970 0.030
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.970 0.030
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.970 0.030
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.970 0.030
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.970 0.030
C25.9 Pancreas, unspecified
0.030 0.970 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.030 0.970 0.000
C79 Secondary malignant neoplasm of other sites
0.030 0.970 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.970 0.029
C18.2 Ascending colon
0.029 0.971 0.000
I20.1 Angina pectoris with documented spasm
0.000 0.971 0.029
I12.9 Hypertensive renal disease without renal failure
0.000 0.971 0.029
C80 Malignant neoplasm without specification of site
0.029 0.971 0.000
I63 Cerebral infarction
0.000 0.971 0.029
I51.8 Other ill-defined heart diseases
0.000 0.971 0.029
C45 Mesothelioma
0.028 0.972 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.972 0.028
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.972 0.028
I27.2 Other secondary pulmonary hypertension
0.000 0.972 0.028
I74 Arterial embolism and thrombosis
0.000 0.972 0.028
C25.0 Head of pancreas
0.028 0.972 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.972 0.028
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.972 0.028
I08.9 Multiple valve disease, unspecified
0.000 0.972 0.028
I08.8 Other multiple valve diseases
0.000 0.972 0.028
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.972 0.028
I42.0 Dilated cardiomyopathy
0.000 0.972 0.027
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.973 0.027
I42.8 Other cardiomyopathies
0.000 0.973 0.027
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.973 0.027
I42.6 Alcoholic cardiomyopathy
0.000 0.973 0.027
I42.5 Other restrictive cardiomyopathy
0.000 0.973 0.027
I42.4 Endocardial fibroelastosis
0.000 0.973 0.027
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.973 0.027
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.973 0.027
C26 Malignant neoplasm of other and ill-defined digestive organs
0.027 0.973 0.000
D00-D09 In situ neoplasms
0.027 0.973 0.000
I80 Phlebitis and thrombophlebitis
0.000 0.973 0.027
C82.6 Cutaneous follicle centre lymphoma
0.027 0.973 0.000
C82.5 Diffuse follicle centre lymphoma
0.027 0.973 0.000
C82.4 Follicular lymphoma grade IIIb
0.027 0.973 0.000
C82.3 Follicular lymphoma grade IIIa
0.027 0.973 0.000
C82.2 Large cell, follicular
0.027 0.973 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.027 0.973 0.000
C82.0 Small cleaved cell, follicular
0.027 0.973 0.000
C90.3 Solitary plasmacytoma
0.027 0.973 0.000
C90.2 Plasmacytoma, extramedullary
0.027 0.973 0.000
C90.1 Plasma cell leukaemia
0.027 0.973 0.000
C91 Lymphoid leukaemia
0.027 0.973 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.973 0.027
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.973 0.027
I69.3 Sequelae of cerebral infarction
0.000 0.973 0.027
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.973 0.027
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.973 0.027
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.973 0.027
I70 Atherosclerosis
0.000 0.973 0.027
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.973 0.026
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.974 0.026
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.026 0.974 0.000
I27.0 Primary pulmonary hypertension
0.000 0.974 0.026
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.026 0.974 0.000
C21 Malignant neoplasm of anus and anal canal
0.026 0.974 0.000
C17 Malignant neoplasm of small intestine
0.026 0.974 0.000
C23 Malignant neoplasm of gallbladder
0.026 0.974 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.974 0.026
C18.0 Caecum
0.026 0.974 0.000
I05.9 Mitral valve disease, unspecified
0.000 0.974 0.025
I05.8 Other mitral valve diseases
0.000 0.974 0.025
I05.2 Mitral stenosis with insufficiency
0.000 0.974 0.025
I05.1 Rheumatic mitral insufficiency
0.000 0.974 0.025
I05.0 Mitral stenosis
0.000 0.974 0.025
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.974 0.025
I06.8 Other rheumatic aortic valve diseases
0.000 0.974 0.025
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.974 0.025
I06.1 Rheumatic aortic insufficiency
0.000 0.974 0.025
I06.0 Rheumatic aortic stenosis
0.000 0.974 0.025
I09.9 Rheumatic heart disease, unspecified
0.000 0.974 0.025
I09.8 Other specified rheumatic heart diseases
0.000 0.974 0.025
I09.2 Chronic rheumatic pericarditis
0.000 0.974 0.025
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.974 0.025
I09.0 Rheumatic myocarditis
0.000 0.974 0.025
G50-G59 Nerve, nerve root and plexus disorders
0.026 0.974 0.000
C81.9 Hodgkin's disease, unspecified
0.026 0.974 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.974 0.025
I72 Other aneurysm
0.000 0.974 0.025
Chapter I Certain infectious and parasitic diseases
0.026 0.974 0.000
Chapter VI Diseases of the nervous system
0.026 0.974 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.025 0.975 0.000
I07.9 Tricuspid valve disease, unspecified
0.000 0.975 0.025
I07.8 Other tricuspid valve diseases
0.000 0.975 0.025
I07.2 Tricuspid stenosis with insufficiency
0.000 0.975 0.025
I07.0 Tricuspid stenosis
0.000 0.975 0.025
I27.9 Pulmonary heart disease, unspecified
0.000 0.975 0.025
I27.8 Other specified pulmonary heart diseases
0.000 0.975 0.025
I27.1 Kyphoscoliotic heart disease
0.000 0.975 0.025
C79.6 Secondary malignant neoplasm of ovary
0.025 0.975 0.000
# Top node
0.025 0.975 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.025 0.975 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.025 0.975 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.025 0.975 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.025 0.975 0.000
C46 Kaposi's sarcoma
0.025 0.975 0.000
I60 Subarachnoid haemorrhage
0.000 0.975 0.024
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.975 0.024
I01.8 Other acute rheumatic heart disease
0.000 0.975 0.024
I01.2 Acute rheumatic myocarditis
0.000 0.975 0.024
I01.1 Acute rheumatic endocarditis
0.000 0.975 0.024
I01.0 Acute rheumatic pericarditis
0.000 0.975 0.024
I02.9 Rheumatic chorea without heart involvement
0.000 0.975 0.024
I02.0 Rheumatic chorea with heart involvement
0.000 0.975 0.024
I07.1 Tricuspid insufficiency
0.000 0.975 0.024
I51.9 Heart disease, unspecified
0.000 0.975 0.024
I67 Other cerebrovascular diseases
0.000 0.976 0.024
C25.8 Overlapping lesion of pancreas
0.024 0.976 0.000
C25.7 Other parts of pancreas
0.024 0.976 0.000
C25.4 Endocrine pancreas
0.024 0.976 0.000
C25.3 Pancreatic duct
0.024 0.976 0.000
C25.2 Tail of pancreas
0.024 0.976 0.000
C25.1 Body of pancreas
0.024 0.976 0.000
L03.1 Cellulitis of other parts of limb
0.000 0.976 0.024
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.976 0.024
C16 Malignant neoplasm of stomach
0.024 0.976 0.000
C81.7 Other Hodgkin's disease
0.024 0.976 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.024 0.976 0.000
C81.3 Lymphocytic depletion
0.024 0.976 0.000
C81.2 Mixed cellularity
0.024 0.976 0.000
C81.1 Nodular sclerosis
0.024 0.976 0.000
C81.0 Lymphocytic predominance
0.024 0.976 0.000
G56 Mononeuropathies of upper limb
0.024 0.976 0.000
A00-A09 Intestinal infectious diseases
0.024 0.976 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.024 0.976 0.000
C76.8 Overlapping lesion of other and ill-defined sites
0.024 0.976 0.000
C76.7 Other ill-defined sites
0.024 0.976 0.000
C76.5 Lower limb
0.024 0.976 0.000
C76.4 Upper limb
0.024 0.976 0.000
C76.3 Pelvis
0.024 0.976 0.000
C76.2 Abdomen
0.024 0.976 0.000
C76.1 Thorax
0.024 0.976 0.000
C76.0 Head, face and neck
0.024 0.976 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.024 0.976 0.000
I71 Aortic aneurysm and dissection
0.000 0.976 0.024
I61 Intracerebral haemorrhage
0.000 0.976 0.024
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.976 0.023
C15 Malignant neoplasm of oesophagus
0.024 0.976 0.000
I73 Other peripheral vascular diseases
0.000 0.976 0.023
C79.7 Secondary malignant neoplasm of adrenal gland
0.023 0.977 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.977 0.023
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.977 0.023
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.977 0.023
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.023 0.977 0.000
I20.9 Angina pectoris, unspecified
0.000 0.977 0.023
I12.0 Hypertensive renal disease with renal failure
0.000 0.977 0.023
C18.8 Overlapping lesion of colon
0.023 0.977 0.000
C18.6 Descending colon
0.023 0.977 0.000
C18.5 Splenic flexure
0.023 0.977 0.000
C18.4 Transverse colon
0.023 0.977 0.000
C18.3 Hepatic flexure
0.023 0.977 0.000
C18.1 Appendix
0.023 0.977 0.000
C83.3 Large cell (diffuse)
0.023 0.977 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.023 0.977 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.023 0.977 0.000
C83.7 Burkitt's tumour
0.023 0.977 0.000
C83.6 Undifferentiated (diffuse)
0.023 0.977 0.000
C83.5 Lymphoblastic (diffuse)
0.023 0.977 0.000
C83.4 Immunoblastic (diffuse)
0.023 0.977 0.000
C83.2 Mixed small and large cell (diffuse)
0.023 0.977 0.000
C83.1 Small cleaved cell (diffuse)
0.023 0.977 0.000
C83.0 Small cell (diffuse)
0.023 0.977 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.023 0.977 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.023 0.977 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.023 0.977 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.023 0.977 0.000
C84.5 Other and unspecified T-cell lymphomas
0.023 0.977 0.000
C84.4 Peripheral T-cell lymphoma
0.023 0.977 0.000
C84.3 Lymphoepithelioid lymphoma
0.023 0.977 0.000
C84.2 T-zone lymphoma
0.023 0.977 0.000
C84.1 Sezary's diease
0.023 0.977 0.000
C84.0 Mycosis fungoides
0.023 0.977 0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.023 0.977 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.023 0.977 0.000
C86.4 Blastic NK-cell lymphoma
0.023 0.977 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.023 0.977 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.023 0.977 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.023 0.977 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.023 0.977 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.023 0.977 0.000
C88.7 Other malignant immunoproliferative diseases
0.023 0.977 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.023 0.977 0.000
C88.3 Immunoproliferative small intestinal disease
0.023 0.977 0.000
C88.2 Gamma heavy chain disease
0.023 0.977 0.000
C88.1 Alpha heavy chain disease
0.023 0.977 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.023 0.977 0.000
C93.9 Monocytic leukaemia, unspecified
0.023 0.977 0.000
C93.7 Other monocytic leukaemia
0.023 0.977 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.023 0.977 0.000
C93.2 Subacute monocytic leukaemia
0.023 0.977 0.000
C93.1 Chronic monocytic leukaemia
0.023 0.977 0.000
C93.0 Acute monocytic leukaemia
0.023 0.977 0.000
C94.7 Other specified leukaemias
0.023 0.977 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.023 0.977 0.000
C94.5 Acute myelofibrosis
0.023 0.977 0.000
C94.4 Acute panmyelosis
0.023 0.977 0.000
C94.3 Mast cell leukaemia
0.023 0.977 0.000
C94.2 Acute megakaryoblastic leukaemia
0.023 0.977 0.000
C94.1 Chronic erythraemia
0.023 0.977 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.023 0.977 0.000
C95.9 Leukaemia, unspecified
0.023 0.977 0.000
C95.7 Other leukaemia of unspecified cell type
0.023 0.977 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.023 0.977 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.023 0.977 0.000
C95.0 Acute leukaemia of unspecified cell type
0.023 0.977 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.023 0.977 0.000
C96.8 Histiocytic sarcoma
0.023 0.977 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.023 0.977 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.023 0.977 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.023 0.977 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.023 0.977 0.000
C96.3 True histiocytic lymphoma
0.023 0.977 0.000
C96.2 Malignant mast cell tumour
0.023 0.977 0.000
C96.1 Malignant histiocytosis
0.023 0.977 0.000
C96.0 Letterer-Siwe disease
0.023 0.977 0.000
Chapter V Mental and behavioural disorders
0.023 0.977 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.977 0.022
I28.8 Other specified diseases of pulmonary vessels
0.000 0.977 0.022
I28.1 Aneurysm of pulmonary artery
0.000 0.977 0.022
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.977 0.022
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.977 0.023
C45.9 Mesothelioma, unspecified
0.023 0.977 0.000
C45.0 Mesothelioma of pleura
0.023 0.977 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.977 0.022
I62.1 Nontraumatic extradural haemorrhage
0.000 0.977 0.022
I42.2 Other hypertrophic cardiomyopathy
0.000 0.977 0.022
I63.9 Cerebral infarction, unspecified
0.000 0.977 0.022
C34 Malignant neoplasm of bronchus and lung
0.022 0.978 0.000
C09 Malignant neoplasm of tonsil
0.022 0.978 0.000
I42.9 Cardiomyopathy, unspecified
0.000 0.978 0.022
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.022 0.978 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.022 0.978 0.000
C32 Malignant neoplasm of larynx
0.022 0.978 0.000
C31 Malignant neoplasm of accessory sinuses
0.022 0.978 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.022 0.978 0.000
C37 Malignant neoplasm of thymus
0.022 0.978 0.000
C33 Malignant neoplasm of trachea
0.022 0.978 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.022 0.978 0.000
C13 Malignant neoplasm of hypopharynx
0.022 0.978 0.000
C11 Malignant neoplasm of nasopharynx
0.022 0.978 0.000
C10 Malignant neoplasm of oropharynx
0.022 0.978 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.022 0.978 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.022 0.978 0.000
C05 Malignant neoplasm of palate
0.022 0.978 0.000
C04 Malignant neoplasm of floor of mouth
0.022 0.978 0.000
C03 Malignant neoplasm of gum
0.022 0.978 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.022 0.978 0.000
C00 Malignant neoplasm of lip
0.022 0.978 0.000
C12 Malignant neoplasm of pyriform sinus
0.022 0.978 0.000
C07 Malignant neoplasm of parotid gland
0.022 0.978 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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