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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12101657
log Bayes Factor = 11.5945
Chromosome 15   position 49,043,765  (GRCh37) Explore rs12101657 on Ensembl!
Variant rs12101657 is part of Cluster X0117

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C79 Secondary malignant neoplasm of other sites
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.999 0.001 0.000
H02 Other disorders of eyelid
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.997 0.003 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.994 0.006 0.000
Chapter X Diseases of the respiratory system
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.993 0.007 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.991 0.009 0.000
D69 Purpura and other haemorrhagic conditions
0.988 0.012 0.000
J95-J99 Other diseases of the respiratory system
0.988 0.012 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.986 0.014 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.983 0.017 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.983 0.017 0.000
J98 Other respiratory disorders
0.982 0.018 0.000
D69.6 Thrombocytopenia, unspecified
0.980 0.020 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.980 0.020 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.978 0.022 0.000
J98.4 Other disorders of lung
0.970 0.030 0.000
D80-D89 Certain disorders involving the immune mechanism
0.969 0.031 0.000
C34 Malignant neoplasm of bronchus and lung
0.969 0.031 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.967 0.033 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.966 0.034 0.000
H02.4 Ptosis of eyelid
0.965 0.035 0.000
H02.3 Blepharochalasis
0.960 0.040 0.000
S32 Fracture of lumbar spine and pelvis
0.947 0.053 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.944 0.056 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.944 0.056 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.942 0.058 0.000
J30-J39 Other diseases of upper respiratory tract
0.941 0.059 0.000
H04 Disorders of lachrymal system
0.938 0.062 0.000
C34.9 Bronchus or lung, unspecified
0.937 0.063 0.000
H02.8 Other specified disorders of eyelid
0.933 0.067 0.000
D86 Sarcoidosis
0.933 0.067 0.000
C78.0 Secondary malignant neoplasm of lung
0.925 0.075 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.920 0.080 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.918 0.082 0.000
S32.5 Fracture of pubis
0.916 0.084 0.000
M40-M43 Deforming dorsopathies
0.915 0.085 0.000
D60-D64 Aplastic and other anaemias
0.915 0.085 0.000
M86-M90 Other osteopathies
0.914 0.086 0.000
M65-M68 Disorders of synovium and tendon
0.901 0.099 0.000
C34.2 Middle lobe, bronchus or lung
0.899 0.101 0.000
H01 Other inflammation of eyelid
0.899 0.101 0.000
H00 Hordeolum and chalazion
0.899 0.101 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.897 0.103 0.000
S32.50 Fracture of pubis (closed)
0.894 0.106 0.000
S00-S09 Injuries to the head
0.892 0.108 0.000
M20-M25 Other joint disorders
0.886 0.114 0.000
C83.3 Large cell (diffuse)
0.881 0.119 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.879 0.121 0.000
S09 Other and unspecified injuries of head
0.877 0.123 0.000
H02.5 Other disorders affecting eyelid function
0.873 0.127 0.000
D75 Other diseases of blood and blood-forming organs
0.870 0.130 0.000
Y43 Primarily systemic agents
0.868 0.132 0.000
S09.9 Unspecified injury of head
0.867 0.133 0.000
W20-W49 Exposure to inanimate mechanical forces
0.865 0.135 0.000
M20 Acquired deformities of fingers and toes
0.865 0.135 0.000
Y52 Agents primarily affecting the cardiovascular system
0.863 0.137 0.000
S90-S99 Injuries to the ankle and foot
0.863 0.137 0.000
C85.1 B-cell lymphoma, unspecified
0.860 0.140 0.000
S20-S29 Injuries to the thorax
0.856 0.144 0.000
C60-C63 Malignant neoplasms of male genital organs
0.855 0.145 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.853 0.147 0.000
M20.1 Hallux valgus (acquired)
0.853 0.147 0.000
D86.9 Sarcoidosis, unspecified
0.853 0.147 0.000
J98.8 Other specified respiratory disorders
0.852 0.148 0.000
J35 Chronic diseases of tonsils and adenoids
0.851 0.149 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.851 0.149 0.000
C78.7 Secondary malignant neoplasm of liver
0.849 0.151 0.000
S80-S89 Injuries to the knee and lower leg
0.847 0.153 0.000
Q80-Q89 Other congenital malformations
0.847 0.153 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.846 0.154 0.000
J38.3 Other diseases of vocal cords
0.844 0.156 0.000
C92 Myeloid leukaemia
0.844 0.156 0.000
H00.1 Chalazion
0.843 0.157 0.000
V10-V19 Pedal cyclist injured in transport accident
0.839 0.160 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.832 0.168 0.000
Y40 Systemic antibiotics
0.828 0.172 0.000
V80-V89 Other land transport accidents
0.828 0.172 0.000
H01.0 Blepharitis
0.827 0.173 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.824 0.176 0.000
M65 Synovitis and tenosynovitis
0.824 0.176 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.824 0.176 0.000
C77.1 Intrathoracic lymph nodes
0.822 0.178 0.000
D69.9 Haemorrhagic condition, unspecified
0.820 0.180 0.000
D55-D59 Haemolytic anaemias
0.818 0.182 0.000
H04.1 Other disorders of lachrymal gland
0.817 0.183 0.000
Q60-Q64 Congenital malformations of the urinary system
0.817 0.183 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.817 0.183 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.817 0.183 0.000
M90 Osteopathies in diseases classified elsewhere
0.814 0.186 0.000
M41 Scoliosis
0.813 0.187 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.812 0.188 0.000
C64-C68 Malignant neoplasms of urinary tract
0.811 0.189 0.000
D69.5 Secondary thrombocytopenia
0.811 0.189 0.000
Q50-Q56 Congenital malformations of genital organs
0.810 0.190 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.802 0.198 0.000
J32 Chronic sinusitis
0.802 0.198 0.000
M91-M94 Chondropathies
0.802 0.198 0.000
S50-S59 Injuries to the elbow and forearm
0.802 0.198 0.000
Y57 Other and unspecified drugs and medicaments
0.801 0.199 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.800 0.199 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.796 0.204 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.796 0.204 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.794 0.206 0.000
S32.1 Fracture of sacrum
0.790 0.210 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.790 0.210 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.789 0.211 0.000
D80 Immunodeficiency with predominantly antibody defects
0.789 0.211 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.788 0.212 0.000
C78.2 Secondary malignant neoplasm of pleura
0.787 0.212 0.000
M89 Other disorders of bone
0.786 0.214 0.000
D86.0 Sarcoidosis of lung
0.786 0.214 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.782 0.218 0.000
Y00-Y09 Assault
0.782 0.218 0.000
M34 Systemic sclerosis
0.780 0.220 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.778 0.222 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.778 0.222 0.000
S10-S19 Injuries to the neck
0.777 0.223 0.000
D75.2 Essential thrombocytosis
0.776 0.224 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.775 0.225 0.000
J38.7 Other diseases of larynx
0.775 0.225 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.774 0.226 0.000
D72 Other disorders of white blood cells
0.773 0.227 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.771 0.229 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.770 0.230 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.769 0.231 0.000
C77.2 Intra-abdominal lymph nodes
0.769 0.231 0.000
J09-J18 Influenza and pneumonia
0.768 0.232 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.767 0.233 0.000
H04.2 Epiphora
0.763 0.237 0.000
C77.5 Intrapelvic lymph nodes
0.763 0.237 0.000
J98.9 Respiratory disorder, unspecified
0.763 0.237 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.763 0.237 0.000
J38.4 Oedema of larynx
0.762 0.238 0.000
S32.4 Fracture of acetabulum
0.761 0.239 0.000
D63.0 Anaemia in neoplastic disease
0.761 0.239 0.000
D86.1 Sarcoidosis of lymph nodes
0.760 0.240 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.760 0.240 0.000
C79.6 Secondary malignant neoplasm of ovary
0.759 0.241 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.759 0.241 0.000
C79.2 Secondary malignant neoplasm of skin
0.759 0.241 0.000
D84 Other immunodeficiencies
0.755 0.245 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.754 0.246 0.000
C34.1 Upper lobe, bronchus or lung
0.753 0.247 0.000
H02.1 Ectropion of eyelid
0.753 0.247 0.000
C32 Malignant neoplasm of larynx
0.753 0.247 0.000
M43 Other deforming dorsopathies
0.753 0.247 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.752 0.248 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.751 0.249 0.000
C61 Malignant neoplasm of prostate
0.751 0.249 0.000
T00-T07 Injuries involving multiple body regions
0.751 0.249 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.750 0.250 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.748 0.252 0.000
H02.6 Xanthelasma of eyelid
0.748 0.252 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.746 0.254 0.000
V20-V29 Motorcycle rider injured in transport accident
0.743 0.257 0.000
S92 Fracture of foot, except ankle
0.743 0.257 0.000
M90.7 Fracture of bone in neoplastic disease
0.743 0.257 0.000
C92.0 Acute myeloid leukaemia
0.742 0.258 0.000
S32.3 Fracture of ilium
0.742 0.258 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.741 0.259 0.000
S40-S49 Injuries to the shoulder and upper arm
0.740 0.260 0.000
M41.9 Scoliosis, unspecified
0.740 0.260 0.000
C88 Malignant immunoproliferative diseases
0.740 0.260 0.000
Y45.1 Salicylates
0.740 0.260 0.000
M23 Internal derangement of knee
0.739 0.261 0.000
J38.6 Stenosis of larynx
0.737 0.263 0.000
D61 Other aplastic anaemias
0.736 0.263 0.000
M60-M63 Disorders of muscles
0.736 0.264 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.736 0.264 0.000
V40-V49 Car occupant injured in transport accident
0.736 0.264 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.734 0.266 0.000
S70-S79 Injuries to the hip and thigh
0.733 0.267 0.000
M40 Kyphosis and lordosis
0.732 0.268 0.000
S36 Injury of intra-abdominal organs
0.732 0.268 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.731 0.269 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.731 0.269 0.000
J40-J47 Chronic lower respiratory diseases
0.730 0.270 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.730 0.270 0.000
C83.1 Small cleaved cell (diffuse)
0.729 0.271 0.000
H21 Other disorders of iris and ciliary body
0.729 0.271 0.000
Chapter I Certain infectious and parasitic diseases
0.727 0.273 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.727 0.273 0.000
T79-T79 Certain early complications of trauma
0.727 0.273 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.725 0.275 0.000
Y43.3 Other antineoplastic drugs
0.724 0.276 0.000
H10-H13 Disorders of conjunctiva
0.723 0.277 0.000
C77.4 Inguinal and lower limb lymph nodes
0.721 0.279 0.000
M67 Other disorders of synovium and tendon
0.720 0.280 0.000
X20-X29 Contact with venomous animals and plants
0.720 0.280 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.717 0.283 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.717 0.283 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.716 0.283 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.716 0.284 0.000
H02.2 Lagophthalmos
0.716 0.284 0.000
J32.0 Chronic maxillary sinusitis
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
S27 Injury of other and unspecified intrathoracic organs
0.715 0.285 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.715 0.285 0.000
W44 Foreign body entering into or through eye or natural orifice
0.714 0.286 0.000
W22 Striking against or struck by other objects
0.713 0.287 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.713 0.287 0.000
C95 Leukaemia of unspecified cell type
0.713 0.287 0.000
C94 Other leukaemias of specified cell type
0.713 0.287 0.000
C93 Monocytic leukaemia
0.713 0.287 0.000
C86 Other specified types of T/NK-cell lymphoma
0.713 0.287 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.713 0.287 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
W50-W64 Exposure to animate mechanical forces
0.712 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.288 0.000
D67 Hereditary factor IX deficiency
0.711 0.289 0.000
D66 Hereditary factor VIII deficiency
0.711 0.289 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.711 0.289 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.710 0.290 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.709 0.291 0.000
D69.8 Other specified haemorrhagic conditions
0.709 0.291 0.000
D69.4 Other primary thrombocytopenia
0.709 0.291 0.000
D69.2 Other nonthrombocytopenic purpura
0.709 0.291 0.000
D69.1 Qualitative platelet defects
0.709 0.291 0.000
D69.0 Allergic purpura
0.709 0.291 0.000
J96 Respiratory failure, not elsewhere classified
0.708 0.292 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.708 0.292 0.000
Q51 Congenital malformations of uterus and cervix
0.708 0.292 0.000
M80-M85 Disorders of bone density and structure
0.708 0.292 0.000
M20.4 Other hammer toe(s) (acquired)
0.708 0.292 0.000
M86 Osteomyelitis
0.707 0.293 0.000
Y59 Other and unspecified vaccines and biological substances
0.707 0.293 0.000
Y58 Bacterial vaccines
0.707 0.293 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.707 0.293 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.707 0.293 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.707 0.293 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.707 0.293 0.000
Y48 Anaesthetics and therapeutic gases
0.707 0.293 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.707 0.293 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.707 0.293 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.706 0.293 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.705 0.295 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.705 0.295 0.000
C31 Malignant neoplasm of accessory sinuses
0.705 0.295 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.705 0.295 0.000
C37 Malignant neoplasm of thymus
0.705 0.295 0.000
C33 Malignant neoplasm of trachea
0.705 0.295 0.000
H20 Iridocyclitis
0.705 0.295 0.000
X50-X57 Overexertion, travel and privation
0.704 0.295 0.000
M20.3 Other deformity of hallux (acquired)
0.704 0.295 0.000
J98.6 Disorders of diaphragm
0.704 0.296 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.704 0.296 0.000
J98.3 Compensatory emphysema
0.704 0.296 0.000
J98.2 Interstitial emphysema
0.704 0.296 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.702 0.297 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.702 0.297 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.701 0.299 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.701 0.299 0.000
C77.8 Lymph nodes of multiple regions
0.699 0.301 0.000
T92 Sequelae of injuries of upper limb
0.699 0.301 0.000
S83.2 Tear of meniscus, current
0.698 0.302 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.698 0.302 0.000
T91 Sequelae of injuries of neck and trunk
0.698 0.302 0.000
J38.1 Polyp of vocal cord and larynx
0.697 0.302 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.697 0.303 0.000
H02.0 Entropion and trichiasis of eyelid
0.696 0.304 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.695 0.305 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.695 0.305 0.000
D83 Common variable immunodeficiency
0.695 0.305 0.000
D82 Immunodeficiency associated with other major defects
0.695 0.305 0.000
D81 Combined immunodeficiencies
0.695 0.305 0.000
C34.8 Overlapping lesion of bronchus and lung
0.694 0.305 0.000
D86.8 Sarcoidosis of other and combined sites
0.694 0.306 0.000
M23.3 Other meniscus derangements
0.694 0.306 0.000
H05 Disorders of orbit
0.693 0.306 0.000
Q89 Other congenital malformations, not elsewhere classified
0.693 0.307 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.693 0.307 0.000
Q35-Q37 Cleft lip and cleft palate
0.693 0.307 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.693 0.307 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.693 0.307 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.693 0.307 0.000
S37 Injury of urinary and pelvic organs
0.693 0.307 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.693 0.307 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.693 0.307 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.693 0.307 0.000
S31 Open wound of abdomen, lower back and pelvis
0.693 0.307 0.000
Y44 Agents primarily affecting blood constituents
0.692 0.308 0.000
H04.8 Other disorders of lachrymal system
0.692 0.308 0.000
M20.0 Deformity of finger(s)
0.692 0.308 0.000
S20 Superficial injury of thorax
0.692 0.308 0.000
J32.2 Chronic ethmoidal sinusitis
0.691 0.309 0.000
D59 Acquired haemolytic anaemia
0.688 0.312 0.000
J31.0 Chronic rhinitis
0.688 0.312 0.000
J60-J70 Lung diseases due to external agents
0.687 0.313 0.000
Y43.1 Antineoplastic antimetabolites
0.687 0.313 0.000
M00-M03 Infectious arthropathies
0.687 0.313 0.000
J37 Chronic laryngitis and laryngotracheitis
0.686 0.314 0.000
Y40.9 Systemic antibiotic, unspecified
0.686 0.314 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.682 0.318 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.681 0.319 0.000
Y43.0 Antiallergic and antiemetic drugs
0.679 0.321 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.679 0.321 0.000
S32.2 Fracture of coccyx
0.679 0.321 0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.679 0.321 0.000
S32.10 Fracture of sacrum (closed)
0.678 0.322 0.000
T18 Foreign body in alimentary tract
0.678 0.322 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.677 0.323 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.677 0.323 0.000
C85.0 Lymphosarcoma
0.677 0.323 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.677 0.323 0.000
C83.7 Burkitt's tumour
0.677 0.323 0.000
C83.6 Undifferentiated (diffuse)
0.677 0.323 0.000
C83.5 Lymphoblastic (diffuse)
0.677 0.323 0.000
C83.4 Immunoblastic (diffuse)
0.677 0.323 0.000
C83.2 Mixed small and large cell (diffuse)
0.677 0.323 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.677 0.323 0.000
S05 Injury of eye and orbit
0.676 0.324 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.676 0.324 0.000
S50 Superficial injury of forearm
0.676 0.324 0.000
T66-T78 Other and unspecified effects of external causes
0.676 0.324 0.000
C91 Lymphoid leukaemia
0.675 0.325 0.000
M89.9 Disorder of bone, unspecified
0.675 0.325 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.674 0.326 0.000
Q00-Q07 Congenital malformations of the nervous system
0.673 0.326 0.000
H04.9 Disorder of lachrymal system, unspecified
0.673 0.327 0.000
H04.6 Other changes in lachrymal passages
0.673 0.327 0.000
H04.4 Chronic inflammation of lachrymal passages
0.673 0.327 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.673 0.327 0.000
H04.0 Dacryoadenitis
0.673 0.327 0.000
Q61 Cystic kidney disease
0.672 0.328 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.672 0.328 0.000
S89 Other and unspecified injuries of lower leg
0.671 0.329 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.670 0.330 0.000
S51 Open wound of forearm
0.670 0.330 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.670 0.330 0.000
M34.8 Other forms of systemic sclerosis
0.669 0.331 0.000
M24 Other specific joint derangements
0.669 0.331 0.000
M05-M14 Inflammatory polyarthropathies
0.669 0.331 0.000
D86.3 Sarcoidosis of skin
0.669 0.331 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.669 0.331 0.000
D72.8 Other specified disorders of white blood cells
0.669 0.331 0.000
Y57.9 Drug or medicament, unspecified
0.668 0.331 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.667 0.333 0.000
Q82 Other congenital malformations of skin
0.667 0.333 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.665 0.335 0.000
S86 Injury of muscle and tendon at lower leg level
0.663 0.337 0.000
Q85 Phakomatoses, not elsewhere classified
0.662 0.338 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.662 0.338 0.000
J40 Bronchitis, not specified as acute or chronic
0.661 0.339 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.660 0.340 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.660 0.340 0.000
J38.5 Laryngeal spasm
0.659 0.341 0.000
J38.0 Paralysis of vocal cords and larynx
0.659 0.341 0.000
W21 Striking against or struck by sports equipment
0.659 0.341 0.000
C34.0 Main bronchus
0.659 0.341 0.000
C81 Hodgkin's disease
0.659 0.341 0.000
Chapter XXII Codes for special purposes
0.659 0.341 0.000
C83.0 Small cell (diffuse)
0.658 0.342 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.658 0.342 0.000
D74 Methaemoglobinaemia
0.658 0.342 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.658 0.342 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.658 0.342 0.000
Y45.2 Propionic acid derivatives
0.657 0.342 0.000
S00 Superficial injury of head
0.657 0.343 0.000
S32.51 Fracture of pubis (open)
0.657 0.343 0.000
X60-X84 Intentional self-harm
0.656 0.344 0.000
M42 Spinal osteochondrosis
0.656 0.344 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.656 0.344 0.000
M88 Paget's disease of bone [osteitis deformans]
0.656 0.344 0.000
M92 Other juvenile osteochondrosis
0.654 0.346 0.000
J38.2 Nodules of vocal cords
0.650 0.350 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.650 0.350 0.000
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident
0.649 0.350 0.000
Q63 Other congenital malformations of kidney
0.647 0.353 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.646 0.354 0.000
M66 Spontaneous rupture of synovium and tendon
0.646 0.354 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.645 0.354 0.000
H49 Paralytic strabismus
0.645 0.355 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.645 0.355 0.000
H16 Keratitis
0.645 0.355 0.000
H01.9 Inflammation of eyelid, unspecified
0.645 0.355 0.000
H01.8 Other specified inflammation of eyelid
0.645 0.355 0.000
H01.1 Non-infectious dermatoses of eyelid
0.645 0.355 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.645 0.355 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.644 0.356 0.000
J39 Other diseases of upper respiratory tract
0.643 0.357 0.000
J95.8 Other postprocedural respiratory disorders
0.643 0.357 0.000
S08 Traumatic amputation of part of head
0.640 0.360 0.000
S07 Crushing injury of head
0.640 0.360 0.000
S04 Injury of cranial nerves
0.640 0.360 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.640 0.360 0.000
S91 Open wound of ankle and foot
0.640 0.360 0.000
C65 Malignant neoplasm of renal pelvis
0.639 0.361 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.639 0.361 0.000
H21.8 Other specified disorders of iris and ciliary body
0.637 0.363 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.636 0.364 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.635 0.365 0.000
M33 Dermatopolymyositis
0.635 0.365 0.000
M32 Systemic lupus erythematosus
0.635 0.365 0.000
M30 Polyarteritis nodosa and related conditions
0.635 0.365 0.000
S29 Other and unspecified injuries of thorax
0.633 0.367 0.000
C32.9 Larynx, unspecified
0.631 0.369 0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.631 0.369 0.000
Y04 Assault by bodily force
0.630 0.370 0.000
D63.1 Anaemia in other chronic diseases classified elsewhere
0.630 0.370 0.000
S09.8 Other specified injuries of head
0.629 0.371 0.000
S09.7 Multiple injuries of head
0.629 0.371 0.000
S09.2 Traumatic rupture of ear drum
0.629 0.371 0.000
S09.1 Injury of muscle and tendon of head
0.629 0.371 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.629 0.371 0.000
M43.1 Spondylolisthesis
0.629 0.371 0.000
S32.40 Fracture of acetabulum (closed)
0.628 0.372 0.000
M34.9 Systemic sclerosis, unspecified
0.627 0.373 0.000
H50 Other strabismus
0.626 0.374 0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)
0.626 0.374 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.626 0.374 0.000
Y40.0 Penicillins
0.626 0.374 0.000
D75.0 Familial erythrocytosis
0.624 0.376 0.000
Y43.9 Primarily systemic agent, unspecified
0.622 0.377 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.622 0.377 0.000
Y43.6 Enzymes, not elsewhere classified
0.622 0.377 0.000
Y43.5 Acidifying and alkalising agents
0.622 0.377 0.000
Y43.2 Antineoplastic natural products
0.622 0.377 0.000
C02.9 Tongue, unspecified
0.622 0.378 0.000
Q43 Other congenital malformations of intestine
0.621 0.379 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.621 0.379 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.620 0.379 0.000
W46 Contact with hypodermic needle
0.620 0.379 0.000
W45 Foreign body or object entering through skin
0.620 0.379 0.000
W43 Exposure to vibration
0.620 0.379 0.000
W42 Exposure to noise
0.620 0.379 0.000
W41 Exposure to high-pressure jet
0.620 0.379 0.000
W40 Explosion of other materials
0.620 0.379 0.000
W39 Discharge of firework
0.620 0.379 0.000
W38 Explosion and rupture of other specified pressurised devices
0.620 0.379 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.620 0.379 0.000
W36 Explosion and rupture of gas cylinder
0.620 0.379 0.000
W35 Explosion and rupture of boiler
0.620 0.379 0.000
W34 Discharge from other and unspecified firearms
0.620 0.379 0.000
W33 Rifle, shotgun and larger firearm discharge
0.620 0.379 0.000
W32 Handgun discharge
0.620 0.379 0.000
W31 Contact with other and unspecified machinery
0.620 0.379 0.000
W30 Contact with agricultural machinery
0.620 0.379 0.000
W28 Contact with powered lawn mower
0.620 0.379 0.000
W27 Contact with nonpowered hand tool
0.620 0.379 0.000
W26 Contact with knife, sword or dagger
0.620 0.379 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.620 0.379 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.620 0.379 0.000
W20 Struck by thrown, projected or falling object
0.620 0.379 0.000
C07 Malignant neoplasm of parotid gland
0.619 0.381 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.619 0.381 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.619 0.381 0.000
Y52.7 Peripheral vasodilators
0.619 0.381 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.619 0.381 0.000
Y52.1 Calcium-channel blockers
0.619 0.381 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.619 0.381 0.000
S98 Traumatic amputation of ankle and foot
0.619 0.381 0.000
S97 Crushing injury of ankle and foot
0.619 0.381 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.619 0.381 0.000
S95 Injury of blood vessels at ankle and foot level
0.619 0.381 0.000
S94 Injury of nerves at ankle and foot level
0.619 0.381 0.000
J32.4 Chronic pansinusitis
0.618 0.381 0.000
H43-H45 Disorders of vitreous body and globe
0.618 0.381 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.618 0.382 0.000
X58 Exposure to other specified factors
0.617 0.383 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.617 0.383 0.000
M87 Osteonecrosis
0.615 0.385 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.615 0.385 0.000
C62 Malignant neoplasm of testis
0.614 0.385 0.000
Y43.4 Immunosuppressive agents
0.614 0.386 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.614 0.386 0.000
S26 Injury of heart
0.614 0.386 0.000
S25 Injury of blood vessels of thorax
0.614 0.386 0.000
S24 Injury of nerves and spinal cord at thorax level
0.614 0.386 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.614 0.386 0.000
S21 Open wound of thorax
0.614 0.386 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.613 0.387 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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