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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12109285
log Bayes Factor = 4.39094
Chromosome 5   position 21,749,348  (GRCh37) Explore rs12109285 on Ensembl!
Variant rs12109285 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.985 0.015 0.000
Chapter XI Diseases of the digestive system
0.977 0.023 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.972 0.028 0.000
Chapter X Diseases of the respiratory system
0.958 0.042 0.000
Chapter II Neoplasms
0.948 0.052 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.941 0.059 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.940 0.060 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.938 0.062 0.000
Chapter IX Diseases of the circulatory system
0.926 0.074 0.000
Z87 Personal history of other diseases and conditions
0.920 0.080 0.000
Z51 Other medical care
0.906 0.094 0.000
Z87.1 Personal history of diseases of the digestive system
0.899 0.101 0.000
C50-C50 Malignant neoplasm of breast
0.879 0.121 0.000
J40-J47 Chronic lower respiratory diseases
0.874 0.126 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.870 0.130 0.000
Z85 Personal history of malignant neoplasm
0.860 0.140 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.859 0.141 0.000
Z51.1 Chemotherapy session for neoplasm
0.854 0.146 0.000
R10 Abdominal and pelvic pain
0.843 0.157 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.843 0.157 0.000
K29 Gastritis and duodenitis
0.837 0.163 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.835 0.165 0.000
Chapter XIV Diseases of the genitourinary system
0.832 0.168 0.000
C50 Malignant neoplasm of breast
0.830 0.170 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.828 0.172 0.000
R13 Dysphagia
0.827 0.173 0.000
K21 Gastro-oesophageal reflux disease
0.821 0.179 0.000
J30-J39 Other diseases of upper respiratory tract
0.818 0.182 0.000
J95-J99 Other diseases of the respiratory system
0.812 0.188 0.000
R30-R39 Symptoms and signs involving the urinary system
0.810 0.190 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.799 0.201 0.000
Chapter XX External causes of morbidity and mortality
0.796 0.204 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.795 0.205 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.787 0.213 0.000
I20-I25 Ischaemic heart diseases
0.787 0.213 0.000
C50.9 Breast, unspecified
0.784 0.216 0.000
K30 Dyspepsia
0.783 0.217 0.000
Chapter I Certain infectious and parasitic diseases
0.777 0.223 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.776 0.224 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.775 0.225 0.000
J44 Other chronic obstructive pulmonary disease
0.773 0.227 0.000
Chapter V Mental and behavioural disorders
0.770 0.230 0.000
K55-K64 Other diseases of intestines
0.769 0.231 0.000
R14 Flatulence and related conditions
0.764 0.236 0.000
I60-I69 Cerebrovascular diseases
0.763 0.237 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.763 0.237 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.762 0.237 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.761 0.239 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.759 0.241 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.755 0.245 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.752 0.248 0.000
Z51.5 Palliative care
0.751 0.248 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.746 0.254 0.000
Z98 Other postsurgical states
0.745 0.255 0.000
R10.1 Pain localised to upper abdomen
0.744 0.256 0.000
Z51.0 Radiotherapy session
0.743 0.257 0.000
R00 Abnormalities of heart beat
0.743 0.257 0.000
K29.7 Gastritis, unspecified
0.742 0.258 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.737 0.262 0.000
K65-K67 Diseases of peritoneum
0.737 0.263 0.000
Z92 Personal history of medical treatment
0.735 0.265 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.735 0.265 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.734 0.266 0.000
Z45 Adjustment and management of implanted device
0.733 0.267 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.727 0.273 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.726 0.274 0.000
I30-I52 Other forms of heart disease
0.726 0.274 0.000
Z47 Other orthopaedic follow-up care
0.726 0.274 0.000
M70-M79 Other soft tissue disorders
0.724 0.276 0.000
K25 Gastric ulcer
0.722 0.278 0.000
K40-K46 Hernia
0.720 0.280 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.719 0.281 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.714 0.286 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.712 0.288 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.712 0.288 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.710 0.290 0.000
J98 Other respiratory disorders
0.708 0.292 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.707 0.292 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.706 0.293 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.706 0.293 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.706 0.293 0.000
R47-R49 Symptoms and signs involving speech and voice
0.706 0.293 0.000
Chapter VII Diseases of the eye and adnexa
0.706 0.294 0.000
R15 Faecal incontinence
0.705 0.294 0.000
Chapter VIII Diseases of the ear and mastoid process
0.703 0.297 0.000
K31 Other diseases of stomach and duodenum
0.702 0.298 0.000
K70-K77 Diseases of liver
0.700 0.300 0.000
K35-K38 Diseases of appendix
0.700 0.300 0.000
R31 Unspecified haematuria
0.698 0.302 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.697 0.303 0.000
Z97 Presence of other devices
0.697 0.303 0.000
Z94 Transplanted organ and tissue status
0.697 0.303 0.000
Z93 Artificial opening status
0.697 0.303 0.000
Z89 Acquired absence of limb
0.697 0.303 0.000
Z84 Family history of other conditions
0.697 0.303 0.000
Z83 Family history of other specific disorders
0.697 0.303 0.000
Z81 Family history of mental and behavioural disorders
0.697 0.303 0.000
Chapter VI Diseases of the nervous system
0.692 0.308 0.000
J90-J94 Other diseases of pleura
0.692 0.308 0.000
J43 Emphysema
0.691 0.309 0.000
C64-C68 Malignant neoplasms of urinary tract
0.690 0.310 0.000
Z86 Personal history of certain other diseases
0.687 0.313 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.687 0.313 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.687 0.313 0.000
J60-J70 Lung diseases due to external agents
0.687 0.313 0.000
J00-J06 Acute upper respiratory infections
0.687 0.313 0.000
D50-D53 Nutritional anaemias
0.687 0.313 0.000
J09-J18 Influenza and pneumonia
0.685 0.315 0.000
J33 Nasal polyp
0.681 0.319 0.000
R04 Haemorrhage from respiratory passages
0.680 0.320 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.680 0.320 0.000
D00-D09 In situ neoplasms
0.680 0.320 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.680 0.320 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.680 0.320 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.680 0.320 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.680 0.320 0.000
C51-C58 Malignant neoplasms of female genital organs
0.680 0.320 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.680 0.320 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.680 0.320 0.000
C15-C26 Malignant neoplasms of digestive organs
0.680 0.320 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.680 0.320 0.000
S50-S59 Injuries to the elbow and forearm
0.680 0.320 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.680 0.320 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.675 0.325 0.000
R18 Ascites
0.675 0.325 0.000
R17 Unspecified jaundice
0.675 0.325 0.000
R12 Heartburn
0.675 0.325 0.000
J47 Bronchiectasis
0.674 0.326 0.000
K90-K93 Other diseases of the digestive system
0.674 0.326 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.674 0.326 0.000
K28 Gastrojejunal ulcer
0.674 0.326 0.000
K27 Peptic ulcer, site unspecified
0.674 0.326 0.000
K26 Duodenal ulcer
0.674 0.326 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.674 0.326 0.000
Z54 Convalescence
0.673 0.327 0.000
Z52 Donors of organs and tissues
0.673 0.327 0.000
Z49 Care involving dialysis
0.673 0.327 0.000
Z48 Other surgical follow-up care
0.673 0.327 0.000
Z44 Fitting and adjustment of external prosthetic device
0.673 0.327 0.000
Z43 Attention to artificial openings
0.673 0.327 0.000
Z42 Follow-up care involving plastic surgery
0.673 0.327 0.000
Z41 Procedures for purposes other than remedying health state
0.673 0.327 0.000
Z40 Prophylactic surgery
0.673 0.327 0.000
K80 Cholelithiasis
0.671 0.329 0.000
S80-S89 Injuries to the knee and lower leg
0.670 0.330 0.000
M45-M49 Spondylopathies
0.670 0.330 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.667 0.333 0.000
R11 Nausea and vomiting
0.666 0.334 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.666 0.334 0.000
I21 Acute myocardial infarction
0.666 0.334 0.000
Z50 Care involving use of rehabilitation procedures
0.666 0.334 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.664 0.336 0.000
I05-I09 Chronic rheumatic heart diseases
0.664 0.336 0.000
I00-I02 Acute rheumatic fever
0.664 0.336 0.000
K29.6 Other gastritis
0.661 0.339 0.000
Z87.8 Personal history of other specified conditions
0.660 0.340 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.660 0.340 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.660 0.340 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.660 0.340 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.660 0.340 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.660 0.340 0.000
Z87.0 Personal history of diseases of the respiratory system
0.660 0.340 0.000
D10-D36 Benign neoplasms
0.656 0.343 0.000
D60-D64 Aplastic and other anaemias
0.655 0.345 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.654 0.346 0.000
R07 Pain in throat and chest
0.652 0.348 0.000
M50-M54 Other dorsopathies
0.651 0.349 0.000
Z51.9 Medical care, unspecified
0.650 0.350 0.000
Z51.8 Other specified medical care
0.650 0.350 0.000
Z51.6 Desensitisation to allergens
0.650 0.350 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.650 0.350 0.000
Z51.3 Blood transfusion without reported diagnosis
0.650 0.350 0.000
C50.4 Upper-outer quadrant of breast
0.647 0.353 0.000
N20-N23 Urolithiasis
0.645 0.355 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.644 0.356 0.000
R10.3 Pain localised to other parts of lower abdomen
0.643 0.357 0.000
R10.4 Other and unspecified abdominal pain
0.641 0.358 0.000
M80-M85 Disorders of bone density and structure
0.641 0.359 0.000
Z96 Presence of other functional implants
0.641 0.359 0.000
K22 Other diseases of oesophagus
0.639 0.361 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.638 0.362 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.636 0.364 0.000
M75 Shoulder lesions
0.635 0.365 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.634 0.366 0.000
Z46 Fitting and adjustment of other devices
0.634 0.366 0.000
J98.1 Pulmonary collapse
0.633 0.367 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.633 0.367 0.000
J32 Chronic sinusitis
0.632 0.368 0.000
Z80 Family history of malignant neoplasm
0.631 0.369 0.000
R94 Abnormal results of function studies
0.630 0.370 0.000
K04 Diseases of pulp and periapical tissues
0.630 0.370 0.000
J45 Asthma
0.628 0.372 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.628 0.372 0.000
R00.2 Palpitations
0.627 0.373 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.627 0.373 0.000
J41 Simple and mucopurulent chronic bronchitis
0.627 0.373 0.000
J46 Status asthmaticus
0.627 0.373 0.000
J42 Unspecified chronic bronchitis
0.627 0.373 0.000
J40 Bronchitis, not specified as acute or chronic
0.627 0.373 0.000
K20 Oesophagitis
0.625 0.374 0.000
K59 Other functional intestinal disorders
0.624 0.376 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.624 0.376 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.624 0.376 0.000
R01 Cardiac murmurs and other cardiac sounds
0.624 0.376 0.000
R02 Gangrene, not elsewhere classified
0.624 0.376 0.000
M20-M25 Other joint disorders
0.624 0.376 0.000
N40-N51 Diseases of male genital organs
0.624 0.376 0.000
I25 Chronic ischaemic heart disease
0.623 0.377 0.000
R32 Unspecified urinary incontinence
0.622 0.378 0.000
N30-N39 Other diseases of urinary system
0.622 0.378 0.000
I67 Other cerebrovascular diseases
0.621 0.379 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.618 0.382 0.000
B95-B98 Bacterial, viral and other infectious agents
0.617 0.383 0.000
S00-S09 Injuries to the head
0.617 0.383 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.617 0.383 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.617 0.383 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.617 0.383 0.000
Z85.6 Personal history of leukaemia
0.617 0.383 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.617 0.383 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.617 0.383 0.000
S60-S69 Injuries to the wrist and hand
0.617 0.383 0.000
Z37 Outcome of delivery
0.617 0.383 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.616 0.384 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.616 0.384 0.000
M91-M94 Chondropathies
0.616 0.384 0.000
M86-M90 Other osteopathies
0.616 0.384 0.000
M65-M68 Disorders of synovium and tendon
0.616 0.384 0.000
M60-M63 Disorders of muscles
0.616 0.384 0.000
M40-M43 Deforming dorsopathies
0.616 0.384 0.000
M05-M14 Inflammatory polyarthropathies
0.616 0.384 0.000
M00-M03 Infectious arthropathies
0.616 0.384 0.000
K29.5 Chronic gastritis, unspecified
0.615 0.385 0.000
L20-L30 Dermatitis and eczema
0.614 0.386 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.614 0.386 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.613 0.386 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.613 0.387 0.000
Z51.2 Other chemotherapy
0.613 0.387 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.610 0.390 0.000
N17-N19 Renal failure
0.610 0.390 0.000
R05 Cough
0.608 0.392 0.000
K62 Other diseases of anus and rectum
0.607 0.393 0.000
J34 Other disorders of nose and nasal sinuses
0.607 0.393 0.000
R10.2 Pelvic and perineal pain
0.605 0.395 0.000
R10.0 Acute abdomen
0.605 0.395 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.604 0.395 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.604 0.396 0.000
T79-T79 Certain early complications of trauma
0.604 0.396 0.000
T66-T78 Other and unspecified effects of external causes
0.604 0.396 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.604 0.396 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.604 0.396 0.000
T33-T35 Frostbite
0.604 0.396 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.604 0.396 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.604 0.396 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.604 0.396 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.604 0.396 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.604 0.396 0.000
T00-T07 Injuries involving multiple body regions
0.604 0.396 0.000
S90-S99 Injuries to the ankle and foot
0.604 0.396 0.000
S70-S79 Injuries to the hip and thigh
0.604 0.396 0.000
S40-S49 Injuries to the shoulder and upper arm
0.604 0.396 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.604 0.396 0.000
S20-S29 Injuries to the thorax
0.604 0.396 0.000
S10-S19 Injuries to the neck
0.604 0.396 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.604 0.396 0.000
C34 Malignant neoplasm of bronchus and lung
0.602 0.398 0.000
R39 Other symptoms and signs involving the urinary system
0.602 0.398 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.602 0.398 0.000
K29.9 Gastroduodenitis, unspecified
0.600 0.400 0.000
K29.4 Chronic atrophic gastritis
0.600 0.400 0.000
K29.3 Chronic superficial gastritis
0.600 0.400 0.000
K29.2 Alcoholic gastritis
0.600 0.400 0.000
K29.1 Other acute gastritis
0.600 0.400 0.000
K29.0 Acute haemorrhagic gastritis
0.600 0.400 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.599 0.401 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.599 0.401 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.599 0.401 0.000
J20-J22 Other acute lower respiratory infections
0.598 0.401 0.000
Z12 Special screening examination for neoplasms
0.598 0.401 0.000
N99-N99 Other disorders of the genitourinary system
0.597 0.403 0.000
N60-N64 Disorders of breast
0.597 0.403 0.000
N25-N29 Other disorders of kidney and ureter
0.597 0.403 0.000
N10-N16 Renal tubulo-interstitial diseases
0.597 0.403 0.000
N00-N08 Glomerular diseases
0.597 0.403 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.597 0.403 0.000
R00.0 Tachycardia, unspecified
0.596 0.404 0.000
I10-I15 Hypertensive diseases
0.595 0.405 0.000
C50.8 Overlapping lesion of breast
0.595 0.405 0.000
C50.6 Axillary tail of breast
0.595 0.405 0.000
C50.5 Lower-outer quadrant of breast
0.595 0.405 0.000
C50.3 Lower-inner quadrant of breast
0.595 0.405 0.000
C50.2 Upper-inner quadrant of breast
0.595 0.405 0.000
C50.1 Central portion of breast
0.595 0.405 0.000
C50.0 Nipple and areola
0.595 0.405 0.000
D80-D89 Certain disorders involving the immune mechanism
0.594 0.406 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.594 0.406 0.000
D55-D59 Haemolytic anaemias
0.594 0.406 0.000
C60-C63 Malignant neoplasms of male genital organs
0.590 0.409 0.000
O60-O75 Complications of labour and delivery
0.590 0.410 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.589 0.411 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.589 0.411 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.588 0.412 0.000
R06 Abnormalities of breathing
0.588 0.412 0.000
Z90.1 Acquired absence of breast(s)
0.586 0.413 0.000
Z45.2 Adjustment and management of vascular access device
0.586 0.414 0.000
J39 Other diseases of upper respiratory tract
0.586 0.414 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.586 0.414 0.000
J37 Chronic laryngitis and laryngotracheitis
0.586 0.414 0.000
J35 Chronic diseases of tonsils and adenoids
0.586 0.414 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.586 0.414 0.000
J30 Vasomotor and allergic rhinitis
0.586 0.414 0.000
J36 Peritonsillar abscess
0.586 0.414 0.000
I63 Cerebral infarction
0.586 0.414 0.000
D50 Iron deficiency anaemia
0.585 0.415 0.000
R21 Rash and other nonspecific skin eruption
0.585 0.415 0.000
C79 Secondary malignant neoplasm of other sites
0.584 0.415 0.000
W00-W19 Falls
0.583 0.417 0.000
Z98.0 Intestinal bypass and anastomosis status
0.583 0.417 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.582 0.418 0.000
J96 Respiratory failure, not elsewhere classified
0.582 0.418 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.582 0.418 0.000
R30 Pain associated with micturition
0.581 0.419 0.000
R36 Urethral discharge
0.581 0.419 0.000
R34 Anuria and oliguria
0.581 0.419 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.578 0.422 0.000
K50-K52 Noninfective enteritis and colitis
0.576 0.423 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.573 0.427 0.000
F30-F39 Mood [affective] disorders
0.573 0.427 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.573 0.427 0.000
K86 Other diseases of pancreas
0.573 0.427 0.000
K85 Acute pancreatitis
0.573 0.427 0.000
K83 Other diseases of biliary tract
0.573 0.427 0.000
K82 Other diseases of gallbladder
0.573 0.427 0.000
K81 Cholecystitis
0.573 0.427 0.000
K29.8 Duodenitis
0.571 0.429 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.571 0.429 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.571 0.429 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.571 0.429 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.571 0.429 0.000
Y35-Y36 Legal intervention and operations of war
0.571 0.429 0.000
Y10-Y34 Event of undetermined intent
0.571 0.429 0.000
Y00-Y09 Assault
0.571 0.429 0.000
X85-X99 Assault
0.571 0.429 0.000
X60-X84 Intentional self-harm
0.571 0.429 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.571 0.429 0.000
X50-X57 Overexertion, travel and privation
0.571 0.429 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.571 0.429 0.000
X30-X39 Exposure to forces of nature
0.571 0.429 0.000
X20-X29 Contact with venomous animals and plants
0.571 0.429 0.000
X10-X19 Contact with heat and hot substances
0.571 0.429 0.000
X00-X09 Exposure to smoke, fire and flames
0.571 0.429 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.571 0.429 0.000
W75-W84 Other accidental threats to breathing
0.571 0.429 0.000
W65-W74 Accidental drowning and submersion
0.571 0.429 0.000
W50-W64 Exposure to animate mechanical forces
0.571 0.429 0.000
W20-W49 Exposure to inanimate mechanical forces
0.571 0.429 0.000
V98-V99 Other and unspecified transport accidents
0.571 0.429 0.000
V95-V97 Air and space transport accidents
0.571 0.429 0.000
V90-V94 Water transport accidents
0.571 0.429 0.000
V80-V89 Other land transport accidents
0.571 0.429 0.000
V70-V79 Bus occupant injured in transport accident
0.571 0.429 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.571 0.429 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.571 0.429 0.000
V40-V49 Car occupant injured in transport accident
0.571 0.429 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.571 0.429 0.000
V20-V29 Motorcycle rider injured in transport accident
0.571 0.429 0.000
V10-V19 Pedal cyclist injured in transport accident
0.571 0.429 0.000
V01-V09 Pedestrian injured in transport accident
0.571 0.429 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.570 0.430 0.000
L50-L54 Urticaria and erythema
0.570 0.430 0.000
L40-L45 Papulosquamous disorders
0.570 0.430 0.000
L10-L14 Bullous disorders
0.570 0.430 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.565 0.434 0.000
K66 Other disorders of peritoneum
0.565 0.435 0.000
Z86.7 Personal history of diseases of the circulatory system
0.565 0.435 0.000
C80 Malignant neoplasm without specification of site
0.564 0.436 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.564 0.436 0.000
I24 Other acute ischaemic heart diseases
0.564 0.436 0.000
I23 Certain current complications following acute myocardial infarction
0.564 0.436 0.000
I22 Subsequent myocardial infarction
0.564 0.436 0.000
S52 Fracture of forearm
0.563 0.437 0.000
K02 Dental caries
0.561 0.439 0.000
K44 Diaphragmatic hernia
0.561 0.439 0.000
M75.4 Impingement syndrome of shoulder
0.561 0.439 0.000
R26 Abnormalities of gait and mobility
0.560 0.440 0.000
J43.9 Emphysema, unspecified
0.560 0.440 0.000
I26 Pulmonary embolism
0.559 0.440 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.558 0.442 0.000
B99-B99 Other infectious diseases
0.557 0.443 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.557 0.443 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.557 0.443 0.000
B65-B83 Helminthiases
0.557 0.443 0.000
B50-B64 Protozoal diseases
0.557 0.443 0.000
B35-B49 Mycoses
0.557 0.443 0.000
B25-B34 Other viral diseases
0.557 0.443 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.557 0.443 0.000
B15-B19 Viral hepatitis
0.557 0.443 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.557 0.443 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.557 0.443 0.000
A80-A89 Viral infections of the central nervous system
0.557 0.443 0.000
A75-A79 Rickettsioses
0.557 0.443 0.000
A70-A74 Other diseases caused by chlamydiae
0.557 0.443 0.000
A65-A69 Other spirochaetal diseases
0.557 0.443 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.557 0.443 0.000
A30-A49 Other bacterial diseases
0.557 0.443 0.000
A20-A28 Certain zoonotic bacterial diseases
0.557 0.443 0.000
A15-A19 Tuberculosis
0.557 0.443 0.000
A00-A09 Intestinal infectious diseases
0.557 0.443 0.000
K14 Diseases of tongue
0.557 0.443 0.000
K13 Other diseases of lip and oral mucosa
0.557 0.443 0.000
K12 Stomatitis and related lesions
0.557 0.443 0.000
K11 Diseases of salivary glands
0.557 0.443 0.000
K10 Other diseases of jaws
0.557 0.443 0.000
K09 Cysts of oral region, not elsewhere classified
0.557 0.443 0.000
K08 Other disorders of teeth and supporting structures
0.557 0.443 0.000
K07 Dentofacial anomalies [including malocclusion]
0.557 0.443 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.557 0.443 0.000
K05 Gingivitis and periodontal diseases
0.557 0.443 0.000
K03 Other diseases of hard tissues of teeth
0.557 0.443 0.000
K01 Embedded and impacted teeth
0.557 0.443 0.000
K00 Disorders of tooth development and eruption
0.557 0.443 0.000
I95 Hypotension
0.556 0.444 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.555 0.444 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.555 0.445 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.555 0.445 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.555 0.445 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.555 0.445 0.000
Z82.3 Family history of stroke
0.555 0.445 0.000
Z82.2 Family history of deafness and hearing loss
0.555 0.445 0.000
Z82.1 Family history of blindness and visual loss
0.555 0.445 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.555 0.445 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.555 0.445 0.000
C44 Other malignant neoplasms of skin
0.555 0.445 0.000
R33 Retention of urine
0.555 0.445 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.554 0.446 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.553 0.446 0.000
F99-F99 Unspecified mental disorder
0.552 0.448 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.552 0.448 0.000
F80-F89 Disorders of psychological development
0.552 0.448 0.000
F70-F79 Mental retardation
0.552 0.448 0.000
F60-F69 Disorders of adult personality and behaviour
0.552 0.448 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.552 0.448 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.552 0.448 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.552 0.448 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.551 0.449 0.000
K61 Abscess of anal and rectal regions
0.551 0.449 0.000
K60 Fissure and fistula of anal and rectal regions
0.551 0.449 0.000
K55 Vascular disorders of intestine
0.551 0.449 0.000
I45 Other conduction disorders
0.551 0.449 0.000
I69 Sequelae of cerebrovascular disease
0.547 0.453 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.547 0.453 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.547 0.453 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.547 0.453 0.000
I62 Other nontraumatic intracranial haemorrhage
0.547 0.453 0.000
I61 Intracerebral haemorrhage
0.547 0.453 0.000
I60 Subarachnoid haemorrhage
0.547 0.453 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.547 0.453 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.547 0.453 0.000
Z91.7 Personal history of female genital mutilation
0.547 0.453 0.000
Z91.6 Personal history of other physical trauma
0.547 0.453 0.000
Z91.5 Personal history of self-harm
0.547 0.453 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.547 0.453 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.547 0.453 0.000
Z91.2 Personal history of poor personal hygiene
0.547 0.453 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.547 0.453 0.000
Z60 Problems related to social environment
0.547 0.453 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.547 0.453 0.000
Z39 Postpartum care and examination
0.547 0.453 0.000
Z38 Liveborn infants according to place of birth
0.547 0.453 0.000
Z36 Antenatal screening
0.547 0.453 0.000
Z35 Supervision of high-risk pregnancy
0.547 0.453 0.000
Z34 Supervision of normal pregnancy
0.547 0.453 0.000
Z32 Pregnancy examination and test
0.547 0.453 0.000
Z31 Procreative management
0.547 0.453 0.000
Z33 Pregnant state, incidental
0.547 0.453 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.546 0.454 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.546 0.454 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.546 0.454 0.000
O85-O92 Complications predominantly related to the puerperium
0.546 0.454 0.000
O80-O84 Delivery
0.546 0.454 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.546 0.454 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.546 0.454 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.546 0.454 0.000
O00-O08 Pregnancy with abortive outcome
0.546 0.454 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.546 0.454 0.000
M15-M19 Arthrosis
0.544 0.455 0.000
J33.9 Nasal polyp, unspecified
0.543 0.457 0.000
J33.0 Polyp of nasal cavity
0.543 0.457 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.543 0.457 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.542 0.458 0.000
Z13 Special screening examination for other diseases and disorders
0.542 0.458 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.542 0.458 0.000
Z10 Routine general health check-up of defined subpopulation
0.542 0.458 0.000
Z04 Examination and observation for other reasons
0.542 0.458 0.000
Z02 Examination and encounter for administrative purposes
0.542 0.458 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.542 0.458 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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