TreeWAS – Variant ID: rs12154208

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
Chapter VI Diseases of the nervous system	0.999	0.001
S00-S09 Injuries to the head	0.999	0.001
Chapter XI Diseases of the digestive system	0.999	0.001
Chapter V Mental and behavioural disorders	0.998	0.002
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.996	0.004
Chapter XV Pregnancy, childbirth and the puerperium	0.995	0.005
G40-G47 Episodic and paroxysmal disorders	0.995	0.005
F30-F39 Mood [affective] disorders	0.988	0.012
S80-S89 Injuries to the knee and lower leg	0.985	0.015
G47 Sleep disorders	0.983	0.017
S01 Open wound of head	0.983	0.017
T36-T50 Poisoning by drugs, medicaments and biological substances	0.977	0.023
K65-K67 Diseases of peritoneum	0.976	0.024
O60-O75 Complications of labour and delivery	0.974	0.026
K02 Dental caries	0.970	0.030
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.968	0.032
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.968	0.032
Chapter IX Diseases of the circulatory system	0.966	0.034
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.964	0.036
S82 Fracture of lower leg, including ankle	0.963	0.037
K12 Stomatitis and related lesions	0.961	0.039
F31 Bipolar affective disorder	0.960	0.040
F10 Mental and behavioural disorders due to use of alcohol	0.955	0.045
S01.0 Open wound of scalp	0.951	0.049
K02.9 Dental caries, unspecified	0.951	0.049
G40 Epilepsy	0.949	0.051
D70-D77 Other diseases of blood and blood-forming organs	0.947	0.053
Chapter XX External causes of morbidity and mortality	0.947	0.053
G47.3 Sleep apnoea	0.944	0.056
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.942	0.058
F33 Recurrent depressive disorder	0.942	0.058
D70 Agranulocytosis	0.933	0.067
K50-K52 Noninfective enteritis and colitis	0.933	0.067
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.931	0.069
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.928	0.072
K13 Other diseases of lip and oral mucosa	0.926	0.074
I05-I09 Chronic rheumatic heart diseases	0.914	0.086
K65 Peritonitis	0.912	0.088
R41 Other symptoms and signs involving cognitive functions and awareness	0.912	0.088
K66 Other disorders of peritoneum	0.906	0.094
S06 Intracranial injury	0.904	0.096
O80-O84 Delivery	0.900	0.100
F10.0 Acute intoxication	0.895	0.105
K90-K93 Other diseases of the digestive system	0.892	0.108
S01.9 Open wound of head, part unspecified	0.889	0.111
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.886	0.114
S40-S49 Injuries to the shoulder and upper arm	0.886	0.114
K13.7 Other and unspecified lesions of oral mucosa	0.885	0.115
K51 Ulcerative colitis	0.883	0.117
S82.6 Fracture of lateral malleolus	0.883	0.117
F33.9 Recurrent depressive disorder, unspecified	0.881	0.119
O75 Other complications of labour and delivery, not elsewhere classified	0.877	0.123
R07 Pain in throat and chest	0.876	0.124
O20-O29 Other maternal disorders predominantly related to pregnancy	0.876	0.124
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.873	0.127
S01.5 Open wound of lip and oral cavity	0.873	0.127
S82.4 Fracture of fibula alone	0.872	0.128
W00-W19 Falls	0.870	0.130
K12.2 Cellulitis and abscess of mouth	0.868	0.132
K65.0 Acute peritonitis	0.865	0.135
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.863	0.137
F31.9 Bipolar affective disorder, unspecified	0.862	0.138
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.862	0.138
R07.3 Other chest pain	0.861	0.139
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.860	0.140
I08 Multiple valve diseases	0.860	0.140
K66.0 Peritoneal adhesions	0.859	0.141
S90-S99 Injuries to the ankle and foot	0.856	0.144
R41.0 Disorientation, unspecified	0.854	0.146
G90-G99 Other disorders of the nervous system	0.854	0.146
K12.1 Other forms of stomatitis	0.851	0.149
S09 Other and unspecified injuries of head	0.849	0.151
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.847	0.153
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.846	0.154
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.843	0.157
G20-G26 Extrapyramidal and movement disorders	0.843	0.157
S10-S19 Injuries to the neck	0.842	0.158
S00 Superficial injury of head	0.842	0.158
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.839	0.161
O80 Single spontaneous delivery	0.835	0.165
S02 Fracture of skull and facial bones	0.834	0.166
O66 Other obstructed labour	0.832	0.168
F31.0 Bipolar affective disorder, current episode hypomanic	0.832	0.168
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.831	0.169
I95-I99 Other and unspecified disorders of the circulatory system	0.831	0.169
O85-O92 Complications predominantly related to the puerperium	0.830	0.170
S01.4 Open wound of cheek and temporomandibular area	0.829	0.170
G41 Status epilepticus	0.827	0.173
S82.60 Fracture of lateral malleolus (closed)	0.826	0.174
F10.3 Withdrawal state	0.824	0.176
S82.2 Fracture of shaft of tibia	0.823	0.177
G47.1 Disorders of excessive somnolence [hypersomnias]	0.823	0.177
S05 Injury of eye and orbit	0.822	0.178
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.821	0.179
K35-K38 Diseases of appendix	0.818	0.182
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.817	0.183
K51.9 Ulcerative colitis, unspecified	0.814	0.186
G30-G32 Other degenerative diseases of the nervous system	0.811	0.189
R01 Cardiac murmurs and other cardiac sounds	0.807	0.192
S82.40 Fracture of fibula alone (closed)	0.807	0.193
O63 Long labour	0.807	0.193
G40.9 Epilepsy, unspecified	0.807	0.193
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.805	0.195
Chapter XXII Codes for special purposes	0.803	0.197
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.800	0.200
K92 Other diseases of digestive system	0.799	0.201
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.799	0.201
Chapter I Certain infectious and parasitic diseases	0.794	0.206
F10.2 Dependence syndrome	0.792	0.208
R45 Symptoms and signs involving emotional state	0.792	0.208
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.791	0.209
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.790	0.210
R25 Abnormal involuntary movements	0.790	0.210
W19 Unspecified fall	0.789	0.211
R26 Abnormalities of gait and mobility	0.788	0.212
O64 Obstructed labour due to malposition and malpresentation of foetus	0.788	0.212
O72 Postpartum haemorrhage	0.785	0.214
O80.0 Spontaneous vertex delivery	0.785	0.215
F33.1 Recurrent depressive disorder, current episode moderate	0.782	0.218
D80-D89 Certain disorders involving the immune mechanism	0.780	0.220
I20-I25 Ischaemic heart diseases	0.779	0.221
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.778	0.222
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.777	0.223
K52 Other non-infective gastro-enteritis and colitis	0.775	0.225
O69 Labour and delivery complicated by umbilical cord complications	0.775	0.225
I08.0 Disorders of both mitral and aortic valves	0.775	0.225
D75 Other diseases of blood and blood-forming organs	0.774	0.226
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.774	0.226
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.774	0.226
R74 Abnormal serum enzyme levels	0.773	0.227
S60-S69 Injuries to the wrist and hand	0.772	0.228
T79-T79 Certain early complications of trauma	0.771	0.228
R44 Other symptoms and signs involving general sensations and perceptions	0.771	0.229
G70-G73 Diseases of myoneural junction and muscle	0.771	0.229
F10.1 Harmful use	0.767	0.233
Chapter XXI Factors influencing health status and contact with health services	0.767	0.233
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.767	0.233
O20 Haemorrhage in early pregnancy	0.766	0.234
I80 Phlebitis and thrombophlebitis	0.763	0.237
S82.5 Fracture of medial malleolus	0.763	0.237
K04 Diseases of pulp and periapical tissues	0.762	0.238
S89 Other and unspecified injuries of lower leg	0.761	0.239
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.761	0.239
F60-F69 Disorders of adult personality and behaviour	0.761	0.239
O75.7 Vaginal delivery following previous Caesarean section	0.760	0.240
F10.4 Withdrawal state with delirium	0.760	0.240
K11 Diseases of salivary glands	0.758	0.242
I87 Other disorders of veins	0.758	0.242
F30 Manic episode	0.758	0.242
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.757	0.243
K10 Other diseases of jaws	0.756	0.244
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.756	0.244
W50-W64 Exposure to animate mechanical forces	0.755	0.245
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.754	0.246
R00 Abnormalities of heart beat	0.754	0.246
S42 Fracture of shoulder and upper arm	0.754	0.246
W19.9 Unspecified place	0.752	0.248
K12.0 Recurrent oral aphthae	0.751	0.249
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.751	0.249
I82 Other venous embolism and thrombosis	0.751	0.249
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.751	0.249
O46 Antepartum haemorrhage, not elsewhere classified	0.750	0.250
K70-K77 Diseases of liver	0.750	0.250
I25 Chronic ischaemic heart disease	0.748	0.252
W20-W49 Exposure to inanimate mechanical forces	0.747	0.253
O36 Maternal care for other known or suspected foetal problems	0.747	0.253
I85 Oesophageal varices	0.747	0.253
X40-X49 Accidental poisoning by and exposure to noxious substances	0.743	0.257
I25.8 Other forms of chronic ischaemic heart disease	0.743	0.257
R25.1 Tremor, unspecified	0.743	0.257
S09.9 Unspecified injury of head	0.742	0.258
R76 Other abnormal immunological findings in serum	0.742	0.258
G00-G09 Inflammatory diseases of the central nervous system	0.740	0.260
R09.2 Respiratory arrest	0.736	0.264
G40.8 Other epilepsy	0.731	0.269
S00.8 Superficial injury of other parts of head	0.730	0.270
V40-V49 Car occupant injured in transport accident	0.730	0.270
O70 Perineal laceration during delivery	0.730	0.270
S82.3 Fracture of lower end of tibia	0.728	0.272
K12.3 Oral mucositis (ulcerative)	0.728	0.272
I05 Rheumatic mitral valve diseases	0.728	0.272
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.728	0.272
R07.0 Pain in throat	0.726	0.274
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.725	0.275
G80-G83 Cerebral palsy and other paralytic syndromes	0.725	0.275
Chapter VIII Diseases of the ear and mastoid process	0.725	0.275
R05 Cough	0.725	0.275
Q80-Q89 Other congenital malformations	0.724	0.276
S06.6 Traumatic subarachnoid haemorrhage	0.723	0.277
G62 Other polyneuropathies	0.723	0.277
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.721	0.279
K90 Intestinal malabsorption	0.720	0.280
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.720	0.280
S06.5 Traumatic subdural haemorrhage	0.720	0.280
R47-R49 Symptoms and signs involving speech and voice	0.720	0.280
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.719	0.280
R01.1 Cardiac murmur, unspecified	0.719	0.281
G47.9 Sleep disorder, unspecified	0.719	0.281
T40.2 Other opioids	0.719	0.281
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.718	0.281
I98 Other disorders of circulatory system in diseases classified elsewhere	0.718	0.282
K02.8 Other dental caries	0.717	0.283
O47 False labour	0.717	0.283
O61 Failed induction of labour	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
S08 Traumatic amputation of part of head	0.716	0.284
S07 Crushing injury of head	0.716	0.284
S04 Injury of cranial nerves	0.716	0.284
S03 Dislocation, sprain and strain of joints and ligaments of head	0.716	0.284
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.716	0.284
F70-F79 Mental retardation	0.716	0.284
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.715	0.285
T39.1 4-Aminophenol derivatives	0.715	0.285
K09 Cysts of oral region, not elsewhere classified	0.714	0.286
K03 Other diseases of hard tissues of teeth	0.714	0.286
K00 Disorders of tooth development and eruption	0.714	0.286
G93 Other disorders of brain	0.714	0.286
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.713	0.287
G46 Vascular syndromes of brain in cerebrovascular diseases	0.713	0.287
S82.20 Fracture of shaft of tibia (closed)	0.713	0.287
S81 Open wound of lower leg	0.711	0.288
R74.8 Abnormal levels of other serum enzymes	0.711	0.289
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.710	0.290
V80-V89 Other land transport accidents	0.709	0.291
R03 Abnormal blood-pressure reading, without diagnosis	0.709	0.291
T66-T78 Other and unspecified effects of external causes	0.708	0.292
F38 Other mood [affective] disorders	0.708	0.292
F34 Persistent mood [affective] disorders	0.708	0.292
F39 Unspecified mood [affective] disorder	0.708	0.292
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.708	0.292
G41.9 Status epilepticus, unspecified	0.707	0.293
G44 Other headache syndromes	0.706	0.294
S88 Traumatic amputation of lower leg	0.706	0.294
S87 Crushing injury of lower leg	0.706	0.294
S86 Injury of muscle and tendon at lower leg level	0.706	0.294
S85 Injury of blood vessels at lower leg level	0.706	0.294
S84 Injury of nerves at lower leg level	0.706	0.294
B95-B98 Bacterial, viral and other infectious agents	0.705	0.295
G47.8 Other sleep disorders	0.705	0.295
G47.4 Narcolepsy and cataplexy	0.705	0.295
G47.2 Disorders of the sleep-wake schedule	0.705	0.295
S01.7 Multiple open wounds of head	0.705	0.295
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.704	0.296
F80-F89 Disorders of psychological development	0.703	0.297
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.702	0.298
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.700	0.299
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.700	0.299
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.700	0.299
T46 Poisoning by agents primarily affecting the cardiovascular system	0.700	0.299
T41 Poisoning by anaesthetics and therapeutic gases	0.700	0.299
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.700	0.299
T36 Poisoning by systemic antibiotics	0.700	0.299
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.701	0.299
K38 Other diseases of appendix	0.700	0.300
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.700	0.300
S06.3 Focal brain injury	0.700	0.300
I81 Portal vein thrombosis	0.699	0.301
S91 Open wound of ankle and foot	0.699	0.301
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.698	0.301
G63 Polyneuropathy in diseases classified elsewhere	0.698	0.302
O74 Complications of anaesthesia during labour and delivery	0.698	0.302
O71 Other obstetric trauma	0.698	0.302
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.698	0.302
O65 Obstructed labour due to maternal pelvic abnormality	0.698	0.302
O60 Preterm delivery	0.698	0.302
S80 Superficial injury of lower leg	0.698	0.302
R41.2 Retrograde amnesia	0.698	0.302
S06.2 Diffuse brain injury	0.697	0.303
T15-T19 Effects of foreign body entering through natural orifice	0.696	0.304
K02.5 Caries with pulp exposure	0.696	0.304
K02.4 Odontoclasia	0.696	0.304
K02.3 Arrested dental caries	0.696	0.304
K02.2 Caries of cementum	0.696	0.304
K02.1 Caries of dentin	0.696	0.304
K02.0 Caries limited to enamel	0.696	0.304
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.696	0.304
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.695	0.304
O86 Other puerperal infections	0.695	0.305
X20-X29 Contact with venomous animals and plants	0.694	0.306
Z60 Problems related to social environment	0.694	0.306
R95-R99 Ill-defined and unknown causes of mortality	0.694	0.306
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.694	0.306
F18 Mental and behavioural disorders due to use of volatile solvents	0.694	0.306
F16 Mental and behavioural disorders due to use of hallucinogens	0.694	0.306
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.694	0.306
F14 Mental and behavioural disorders due to use of cocaine	0.694	0.306
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.694	0.306
F12 Mental and behavioural disorders due to use of cannabinoids	0.694	0.306
F11 Mental and behavioural disorders due to use of opioids	0.694	0.306
R09.0 Asphyxia	0.693	0.307
I00-I02 Acute rheumatic fever	0.693	0.307
Y60-Y69 Misadventures to patients during surgical and medical care	0.693	0.307
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.692	0.308
O23 Infections of genito-urinary tract in pregnancy	0.692	0.308
K05 Gingivitis and periodontal diseases	0.691	0.309
D55-D59 Haemolytic anaemias	0.691	0.309
S82.9 Fracture of lower leg, part unspecified	0.690	0.309
S82.7 Multiple fractures of lower leg	0.690	0.309
Q38-Q45 Other congenital malformations of the digestive system	0.690	0.310
O21 Excessive vomiting in pregnancy	0.690	0.310
R40 Somnolence, stupor and coma	0.690	0.310
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.690	0.310
R26.2 Difficulty in walking, not elsewhere classified	0.689	0.311
F31.8 Other bipolar affective disorders	0.688	0.311
F31.7 Bipolar affective disorder, currently in remission	0.688	0.311
F31.6 Bipolar affective disorder, current episode mixed	0.688	0.311
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.688	0.311
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.688	0.311
K92.9 Disease of digestive system, unspecified	0.687	0.312
K51.4 Pseudopolyposis of colon	0.687	0.313
I22 Subsequent myocardial infarction	0.685	0.315
F10.9 Unspecified mental and behavioural disorder	0.685	0.315
F10.8 Other mental and behavioural disorders	0.685	0.315
F10.7 Residual and late-onset psychotic disorder	0.685	0.315
F10.6 Amnesic syndrome	0.685	0.315
F10.5 Psychotic disorder	0.685	0.315
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.684	0.316
O62 Abnormalities of forces of labour	0.684	0.316
Z70-Z76 Persons encountering health services in other circumstances	0.682	0.318
X60-X84 Intentional self-harm	0.681	0.318
S70-S79 Injuries to the hip and thigh	0.681	0.319
G40.7 Petit mal, unspecified, without grand mal seizures	0.680	0.320
G40.5 Special epileptic syndromes	0.680	0.320
G40.4 Other generalised epilepsy and epileptic syndromes	0.680	0.320
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.680	0.320
O75.0 Maternal distress during labour and delivery	0.680	0.320
T42.1 Iminostilbenes	0.680	0.320
I60-I69 Cerebrovascular diseases	0.680	0.320
T42.4 Benzodiazepines	0.680	0.320
S06.8 Other intracranial injuries	0.679	0.321
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.679	0.321
D74 Methaemoglobinaemia	0.679	0.321
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.679	0.321
D71 Functional disorders of polymorphonuclear neutrophils	0.679	0.321
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.679	0.321
Y35-Y36 Legal intervention and operations of war	0.679	0.321
Y10-Y34 Event of undetermined intent	0.679	0.321
Y00-Y09 Assault	0.679	0.321
X85-X99 Assault	0.679	0.321
X58-X59 Accidental exposure to other and unspecified factors	0.679	0.321
X50-X57 Overexertion, travel and privation	0.679	0.321
X30-X39 Exposure to forces of nature	0.679	0.321
X10-X19 Contact with heat and hot substances	0.679	0.321
X00-X09 Exposure to smoke, fire and flames	0.679	0.321
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.679	0.321
W75-W84 Other accidental threats to breathing	0.679	0.321
W65-W74 Accidental drowning and submersion	0.679	0.321
V98-V99 Other and unspecified transport accidents	0.679	0.321
V95-V97 Air and space transport accidents	0.679	0.321
V90-V94 Water transport accidents	0.679	0.321
V70-V79 Bus occupant injured in transport accident	0.679	0.321
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.679	0.321
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.679	0.321
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.679	0.321
V01-V09 Pedestrian injured in transport accident	0.679	0.321
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.677	0.323
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.676	0.324
F40-F48 Neurotic, stress-related and somatoform disorders	0.676	0.324
T88 Other complications of surgical and medical care, not elsewhere classified	0.676	0.324
R46 Symptoms and signs involving appearance and behaviour	0.676	0.324
R43 Disturbances of smell and taste	0.676	0.324
F33.8 Other recurrent depressive disorders	0.675	0.325
F33.4 Recurrent depressive disorder, currently in remission	0.675	0.325
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.675	0.325
F33.0 Recurrent depressive disorder, current episode mild	0.675	0.325
S41 Open wound of shoulder and upper arm	0.674	0.326
R71 Abnormality of red blood cells	0.672	0.328
S83.6 Sprain and strain of other and unspecified parts of knee	0.672	0.328
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.672	0.328
G24 Dystonia	0.672	0.328
O81 Single delivery by forceps and vacuum extractor	0.671	0.329
I84 Haemorrhoids	0.671	0.329
K92.0 Haematemesis	0.671	0.329
Z60.2 Living alone	0.670	0.330
O46.9 Antepartum haemorrhage, unspecified	0.670	0.330
I80.8 Phlebitis and thrombophlebitis of other sites	0.669	0.331
S06.0 Concussion	0.668	0.332
K51.2 Ulcerative (chronic) proctitis	0.668	0.332
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.668	0.332
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.668	0.332
I87.1 Compression of vein	0.667	0.333
O72.1 Other immediate postpartum haemorrhage	0.667	0.333
O36.0 Maternal care for rhesus isoimmunisation	0.667	0.333
D75.1 Secondary polycythaemia	0.666	0.334
I88 Nonspecific lymphadenitis	0.665	0.335
I83 Varicose veins of lower extremities	0.665	0.335
S02.1 Fracture of base of skull	0.664	0.335
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.664	0.336
K13.6 Irritative hyperplasia of oral mucosa	0.664	0.336
K13.5 Oral submucous fibrosis	0.664	0.336
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.664	0.336
K13.3 Hairy leukoplakia	0.664	0.336
K13.1 Cheek and lip biting	0.664	0.336
K51.5 Mucosal proctocolitis	0.664	0.336
H65-H75 Diseases of middle ear and mastoid	0.664	0.336
I07 Rheumatic tricuspid valve diseases	0.664	0.336
I95 Hypotension	0.664	0.336
F99-F99 Unspecified mental disorder	0.663	0.336
K65.9 Peritonitis, unspecified	0.663	0.336
W06 Fall involving bed	0.663	0.337
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.663	0.337
G20 Parkinson's disease	0.662	0.338
Chapter II Neoplasms	0.662	0.338
D86 Sarcoidosis	0.662	0.338
I86 Varicose veins of other sites	0.662	0.338
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.662	0.338
W10 Fall on and from stairs and steps	0.662	0.338
K51.8 Other ulcerative colitis	0.661	0.339
S83.2 Tear of meniscus, current	0.661	0.339
O24 Diabetes mellitus in pregnancy	0.661	0.339
K51.3 Ulcerative (chronic) rectosigmoiditis	0.660	0.340
O75.8 Other specified complications of labour and delivery	0.660	0.340
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.659	0.341
T40.4 Other synthetic narcotics	0.659	0.341
S20-S29 Injuries to the thorax	0.659	0.341
S12 Fracture of neck	0.659	0.341
Y46 Antiepileptics and anti-Parkinsonism drugs	0.658	0.342
O43 Placental disorders	0.658	0.342
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.658	0.342
O63.1 Prolonged second stage (of labour)	0.658	0.342
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.658	0.342
R76.8 Other specified abnormal immunological findings in serum	0.657	0.343
S50-S59 Injuries to the elbow and forearm	0.657	0.343
S82.1 Fracture of upper end of tibia	0.657	0.343
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.656	0.343
I09 Other rheumatic heart diseases	0.655	0.345
I06 Rheumatic aortic valve diseases	0.655	0.345
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.655	0.345
K65.8 Other peritonitis	0.654	0.346
R41.1 Anterograde amnesia	0.654	0.346
S02.2 Fracture of nasal bones	0.654	0.346
R45.8 Other symptoms and signs involving emotional state	0.654	0.346
S02.0 Fracture of vault of skull	0.653	0.347
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.653	0.347
S01.2 Open wound of nose	0.652	0.348
I08.2 Disorders of both aortic and tricuspid valves	0.651	0.349
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.651	0.349
S82.8 Fractures of other parts of lower leg	0.651	0.349
K52.8 Other specified non-infective gastro-enteritis and colitis	0.650	0.350
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.650	0.350
D72 Other disorders of white blood cells	0.650	0.350
K66.9 Disorder of peritoneum, unspecified	0.649	0.351
K66.1 Haemoperitoneum	0.649	0.351
G50-G59 Nerve, nerve root and plexus disorders	0.649	0.351
I08.1 Disorders of both mitral and tricuspid valves	0.649	0.351
G91 Hydrocephalus	0.649	0.351
O20.0 Threatened abortion	0.649	0.351
S06.9 Intracranial injury, unspecified	0.648	0.352
S06.7 Intracranial injury with prolonged coma	0.648	0.352
S06.4 Epidural haemorrhage	0.648	0.352
S06.1 Traumatic cerebral oedema	0.648	0.352
R09.3 Abnormal sputum	0.648	0.352
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.648	0.352
Y48 Anaesthetics and therapeutic gases	0.648	0.352
K92.2 Gastro-intestinal haemorrhage, unspecified	0.648	0.352
K07 Dentofacial anomalies [including malocclusion]	0.647	0.353
F29 Unspecified nonorganic psychosis	0.647	0.353
D66 Hereditary factor VIII deficiency	0.646	0.354
O84 Multiple delivery	0.646	0.354
O83 Other assisted single delivery	0.646	0.354
Y41 Other systemic anti-infectives and antiparasitics	0.643	0.356
F52 Sexual dysfunction, not caused by organic disorder or disease	0.643	0.357
B65-B83 Helminthiases	0.642	0.358
S92 Fracture of foot, except ankle	0.641	0.358
R07.1 Chest pain on breathing	0.641	0.359
O75.2 Pyrexia during labour, not elsewhere classified	0.640	0.359
K70 Alcoholic liver disease	0.640	0.360
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.640	0.360
K93 Disorders of other digestive organs in diseases classified elsewhere	0.640	0.360
I98.2 Oesophageal varices in diseases classified elsewhere	0.638	0.362
S40 Superficial injury of shoulder and upper arm	0.637	0.363
O73 Retained placenta and membranes, without haemorrhage	0.637	0.363
R27 Other lack of coordination	0.637	0.363
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.636	0.364
G25 Other extrapyramidal and movement disorders	0.635	0.365
S49 Other and unspecified injuries of shoulder and upper arm	0.635	0.365
S48 Traumatic amputation of shoulder and upper arm	0.635	0.365
S46 Injury of muscle and tendon at shoulder and upper arm level	0.635	0.365
S45 Injury of blood vessels at shoulder and upper arm level	0.635	0.365
S44 Injury of nerves at shoulder and upper arm level	0.635	0.365
S47 Crushing injury of shoulder and upper arm	0.635	0.365
K08 Other disorders of teeth and supporting structures	0.633	0.366
K51.1 Ulcerative (chronic) ileocolitis	0.633	0.366
G95 Other diseases of spinal cord	0.633	0.367
S82.61 Fracture of lateral malleolus (open)	0.633	0.367
S64 Injury of nerves at wrist and hand level	0.633	0.367
R00.1 Bradycardia, unspecified	0.633	0.367
K92.8 Other specified diseases of digestive system	0.632	0.367
S00.0 Superficial injury of scalp	0.632	0.368
K90.0 Coeliac disease	0.632	0.368
K06 Other disorders of gingiva and edentulous alveolar ridge	0.631	0.369
V20-V29 Motorcycle rider injured in transport accident	0.631	0.369
D73 Diseases of spleen	0.630	0.370
Q50-Q56 Congenital malformations of genital organs	0.630	0.370

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations