TreeWAS – Variant ID: rs12186641

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H65-H75 Diseases of middle ear and mastoid	0.211	0.789	0.000
H66 Suppurative and unspecified otitis media	0.207	0.793	0.000
H71 Cholesteatoma of middle ear	0.198	0.802	0.000
H74 Other disorders of middle ear and mastoid	0.195	0.805	0.000
H66.9 Otitis media, unspecified	0.194	0.806	0.000
H66.3 Other chronic suppurative otitis media	0.189	0.811	0.000
H69 Other disorders of Eustachian tube	0.174	0.826	0.000
Chapter VIII Diseases of the ear and mastoid process	0.174	0.826	0.000
H73 Other disorders of tympanic membrane	0.173	0.827	0.000
H90-H95 Other disorders of ear	0.170	0.830	0.000
H91 Other hearing loss	0.164	0.836	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.162	0.838	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.160	0.839	0.000
H91.9 Hearing loss, unspecified	0.160	0.840	0.000
I25 Chronic ischaemic heart disease	0.159	0.841	0.000
H74.4 Polyp of middle ear	0.158	0.842	0.000
I20 Angina pectoris	0.157	0.843	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.157	0.843	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.154	0.846	0.000
H70 Mastoiditis and related conditions	0.154	0.846	0.000
H65 Nonsuppurative otitis media	0.154	0.846	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.151	0.848	0.000
I25.2 Old myocardial infarction	0.152	0.848	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.151	0.849	0.000
H68 Eustachian salpingitis and obstruction	0.151	0.849	0.000
H67 Otitis media in diseases classified elsewhere	0.151	0.849	0.000
I20-I25 Ischaemic heart diseases	0.151	0.849	0.000
I20.0 Unstable angina	0.151	0.849	0.000
H74.0 Tympanosclerosis	0.149	0.851	0.000
H66.4 Suppurative otitis media, unspecified	0.149	0.851	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.149	0.851	0.000
H66.0 Acute suppurative otitis media	0.149	0.851	0.000
H69.8 Other specified disorders of Eustachian tube	0.148	0.852	0.000
H73.8 Other specified disorders of tympanic membrane	0.145	0.855	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.142	0.858	0.000
I20.9 Angina pectoris, unspecified	0.141	0.859	0.000
I25.5 Ischaemic cardiomyopathy	0.141	0.859	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.140	0.860	0.000
H74.1 Adhesive middle ear disease	0.140	0.860	0.000
I20.1 Angina pectoris with documented spasm	0.139	0.861	0.000
I22 Subsequent myocardial infarction	0.135	0.865	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.133	0.867	0.000
H93 Other disorders of ear, not elsewhere classified	0.132	0.868	0.000
H60-H62 Diseases of external ear	0.129	0.871	0.000
H92 Otalgia and effusion of ear	0.129	0.871	0.000
H65.4 Other chronic nonsuppurative otitis media	0.127	0.873	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.127	0.873	0.000
H69.0 Patulous Eustachian tube	0.125	0.875	0.000
H69.9 Eustachian tube disorder, unspecified	0.124	0.876	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.124	0.876	0.000
H73.1 Chronic myringitis	0.124	0.876	0.000
H73.0 Acute myringitis	0.124	0.876	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.122	0.878	0.000
I20.8 Other forms of angina pectoris	0.122	0.878	0.000
I25.3 Aneurysm of heart	0.121	0.879	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.120	0.880	0.000
H72 Perforation of tympanic membrane	0.119	0.881	0.000
H91.3 Deaf mutism, not elsewhere classified	0.118	0.882	0.000
H91.2 Sudden idiopathic hearing loss	0.118	0.882	0.000
H91.1 Presbycusis	0.118	0.882	0.000
H91.0 Ototoxic hearing loss	0.118	0.882	0.000
H95.1 Other disorders following mastoidectomy	0.117	0.883	0.000
H90 Conductive and sensorineural hearing loss	0.117	0.883	0.000
H91.8 Other specified hearing loss	0.114	0.886	0.000
I25.6 Silent myocardial ischaemia	0.114	0.886	0.000
I25.4 Coronary artery aneurysm	0.114	0.886	0.000
H70.9 Mastoiditis, unspecified	0.114	0.886	0.000
H70.8 Other mastoiditis and related conditions	0.111	0.889	0.000
H70.2 Petrositis	0.111	0.889	0.000
H70.1 Chronic mastoiditis	0.111	0.889	0.000
H70.0 Acute mastoiditis	0.111	0.889	0.000
H65.1 Other acute nonsuppurative otitis media	0.111	0.889	0.000
H65.0 Acute serous otitis media	0.111	0.889	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.110	0.890	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.109	0.891	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.109	0.891	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.109	0.891	0.000
H68.1 Obstruction of Eustachian tube	0.109	0.891	0.000
H68.0 Eustachian salpingitis	0.109	0.891	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.109	0.891	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.109	0.891	0.000
H93.8 Other specified disorders of ear	0.109	0.891	0.000
I23 Certain current complications following acute myocardial infarction	0.108	0.891	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.104	0.895	0.000
H92.0 Otalgia	0.104	0.896	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.102	0.898	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.102	0.898	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.102	0.898	0.000
H60 Otitis externa	0.102	0.898	0.000
I25.1 Atherosclerotic heart disease	0.101	0.899	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.099	0.901	0.000
I22.8 Subsequent myocardial infarction of other sites	0.098	0.902	0.000
H93.3 Disorders of acoustic nerve	0.095	0.905	0.000
H93.2 Other abnormal auditory perceptions	0.095	0.905	0.000
H93.0 Degenerative and vascular disorders of ear	0.095	0.905	0.000
H93.9 Disorder of ear, unspecified	0.094	0.906	0.000
H72.2 Other marginal perforations of tympanic membrane	0.094	0.906	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.093	0.907	0.000
H92.2 Otorrhagia	0.092	0.907	0.000
H90.2 Conductive hearing loss, unspecified	0.091	0.909	0.000
I24 Other acute ischaemic heart diseases	0.090	0.910	0.000
H80-H83 Diseases of inner ear	0.090	0.910	0.000
H65.2 Chronic serous otitis media	0.089	0.911	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.089	0.911	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.088	0.912	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.088	0.912	0.000
H93.1 Tinnitus	0.088	0.912	0.000
H61 Other disorders of external ear	0.087	0.913	0.000
H72.1 Attic perforation of tympanic membrane	0.086	0.914	0.000
H92.1 Otorrhoea	0.084	0.916	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.084	0.916	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.084	0.916	0.000
H72.0 Central perforation of tympanic membrane	0.080	0.919	0.000
H60.8 Other otitis externa	0.080	0.920	0.000
I23.8 Other current complications following acute myocardial infarction	0.078	0.922	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.078	0.922	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.078	0.922	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.078	0.922	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.078	0.922	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.078	0.922	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.078	0.922	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.078	0.922	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.077	0.922	0.000
H60.5 Acute otitis externa, non-infective	0.077	0.923	0.000
H60.1 Cellulitis of external ear	0.076	0.924	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.924	0.076
H72.8 Other perforations of tympanic membrane	0.074	0.926	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.073	0.926	0.000
H60.4 Cholesteatoma of external ear	0.073	0.927	0.000
H60.3 Other infective otitis externa	0.073	0.927	0.000
H60.2 Malignant otitis externa	0.073	0.927	0.000
H60.0 Abscess of external ear	0.073	0.927	0.000
H90.0 Conductive hearing loss, bilateral	0.072	0.928	0.000
H61.3 Acquired stenosis of external ear canal	0.068	0.932	0.000
H81 Disorders of vestibular function	0.068	0.932	0.000
H60.9 Otitis externa, unspecified	0.068	0.932	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.067	0.933	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.067	0.933	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.067	0.933	0.000
H62.2 Otitis externa in mycoses	0.067	0.933	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.067	0.933	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.067	0.933	0.000
H90.5 Sensorineural hearing loss, unspecified	0.066	0.933	0.000
I24.1 Dressler's syndrome	0.065	0.935	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.065	0.935	0.000
H61.2 Impacted cerumen	0.064	0.936	0.000
H90.3 Sensorineural hearing loss, bilateral	0.064	0.936	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.064	0.936	0.000
H65.3 Chronic mucoid otitis media	0.064	0.936	0.000
H61.9 Disorder of external ear, unspecified	0.063	0.936	0.000
H61.1 Non-infective disorders of pinna	0.063	0.937	0.000
H81.2 Vestibular neuronitis	0.058	0.942	0.000
H61.8 Other specified disorders of external ear	0.056	0.944	0.000
I24.8 Other forms of acute ischaemic heart disease	0.056	0.944	0.000
H61.0 Perichondritis of external ear	0.052	0.948	0.000
H81.9 Disorder of vestibular function, unspecified	0.051	0.949	0.000
H81.1 Benign paroxysmal vertigo	0.050	0.950	0.000
H83 Other diseases of inner ear	0.049	0.950	0.000
H81.8 Other disorders of vestibular function	0.049	0.951	0.000
H81.4 Vertigo of central origin	0.049	0.951	0.000
H81.3 Other peripheral vertigo	0.049	0.951	0.000
H80 Otosclerosis	0.046	0.954	0.001
I24.9 Acute ischaemic heart disease, unspecified	0.042	0.958	0.000
H81.0 Meniere's disease	0.036	0.963	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.036	0.964	0.000
H83.9 Disease of inner ear, unspecified	0.036	0.964	0.000
H83.8 Other specified diseases of inner ear	0.036	0.964	0.000
H83.3 Noise effects on inner ear	0.036	0.964	0.000
H83.2 Labyrinthine dysfunction	0.036	0.964	0.000
H83.1 Labyrinthine fistula	0.036	0.964	0.000
H80.8 Other otosclerosis	0.033	0.967	0.001
H80.2 Cochlear otosclerosis	0.033	0.967	0.001
H80.1 Otosclerosis involving oval window, obliterative	0.033	0.967	0.001
H80.0 Otosclerosis involving oval window, nonobliterative	0.033	0.967	0.001
J98.1 Pulmonary collapse	0.000	0.977	0.023
H83.0 Labyrinthitis	0.020	0.979	0.000
J98 Other respiratory disorders	0.000	0.981	0.019
I21 Acute myocardial infarction	0.019	0.981	0.000
Z95.2 Presence of prosthetic heart valve	0.018	0.982	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.983	0.017
Z95 Presence of cardiac and vascular implants and grafts	0.017	0.983	0.000
Z95.4 Presence of other heart-valve replacement	0.016	0.984	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.016	0.984	0.000
J98.4 Other disorders of lung	0.000	0.984	0.016
I21.9 Acute myocardial infarction, unspecified	0.016	0.984	0.000
H80.9 Otosclerosis, unspecified	0.014	0.985	0.001
J98.8 Other specified respiratory disorders	0.000	0.985	0.015
J98.6 Disorders of diaphragm	0.000	0.986	0.014
J98.3 Compensatory emphysema	0.000	0.986	0.014
J98.2 Interstitial emphysema	0.000	0.986	0.014
Z95.5 Presence of coronary angioplasty implant and graft	0.014	0.986	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.014	0.986	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.000	0.986	0.013
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.013	0.987	0.000
J98.9 Respiratory disorder, unspecified	0.000	0.987	0.012
I21.3 Acute transmural myocardial infarction of unspecified site	0.012	0.988	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.012	0.988	0.000
Z95.3 Presence of xenogenic heart valve	0.012	0.988	0.000
Z95.0 Presence of cardiac pacemaker	0.011	0.989	0.000
N10-N16 Renal tubulo-interstitial diseases	0.000	0.990	0.010
J95-J99 Other diseases of the respiratory system	0.000	0.992	0.008
I21.4 Acute subendocardial myocardial infarction	0.008	0.992	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.000	0.993	0.007
N15 Other renal tubulo-interstitial diseases	0.000	0.993	0.007
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.000	0.993	0.007
N11 Chronic tubulo-interstitial nephritis	0.000	0.993	0.007
C77.4 Inguinal and lower limb lymph nodes	0.007	0.993	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.000	0.993	0.007
J96 Respiratory failure, not elsewhere classified	0.000	0.994	0.006
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.994	0.006
Z95.1 Presence of aortocoronary bypass graft	0.006	0.994	0.000
D12.7 Rectosigmoid junction	0.006	0.994	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.000	0.994	0.005
N14.3 Nephropathy induced by heavy metals	0.000	0.994	0.005
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.000	0.994	0.005
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.000	0.994	0.005
N14.0 Analgesic nephropathy	0.000	0.994	0.005
N15.9 Renal tubulo-interstitial disease, unspecified	0.000	0.994	0.005
N15.8 Other specified renal tubulo-interstitial diseases	0.000	0.994	0.005
N15.1 Renal and perinephric abscess	0.000	0.994	0.005
N15.0 Balkan nephropathy	0.000	0.994	0.005
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.000	0.994	0.005
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.000	0.994	0.005
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.000	0.994	0.005
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.000	0.994	0.005
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.000	0.994	0.005
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.000	0.994	0.005
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.000	0.994	0.005
N11.8 Other chronic tubulo-interstitial nephritis	0.000	0.994	0.005
N11.1 Chronic obstructive pyelonephritis	0.000	0.994	0.005
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.994	0.005
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.994	0.005
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.995	0.005
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.000	0.995	0.005
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.995	0.005
N10 Acute tubulo-interstitial nephritis	0.000	0.995	0.005
J99.0 Rheumatoid lung disease	0.000	0.995	0.005
J95.8 Other postprocedural respiratory disorders	0.000	0.995	0.005
J96.9 Respiratory failure, unspecified	0.000	0.995	0.005
J96.1 Chronic respiratory failure	0.000	0.995	0.005
J96.0 Acute respiratory failure	0.000	0.995	0.005
I21.1 Acute transmural myocardial infarction of inferior wall	0.005	0.995	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.005	0.995	0.000
J95.9 Postprocedural respiratory disorder, unspecified	0.000	0.995	0.004
J95.5 Postprocedural subglottic stenosis	0.000	0.995	0.004
J95.4 Mendelson's syndrome	0.000	0.995	0.004
J95.3 Chronic pulmonary insufficiency following surgery	0.000	0.995	0.004
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.000	0.995	0.004
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.000	0.995	0.004
L57.0 Actinic keratosis	0.005	0.995	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.004	0.995	0.000
I08 Multiple valve diseases	0.004	0.995	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.996	0.004
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.996	0.004
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.000	0.996	0.004
I05-I09 Chronic rheumatic heart diseases	0.004	0.996	0.000
Chapter IX Diseases of the circulatory system	0.004	0.996	0.000
H35.8 Other specified retinal disorders	0.000	0.996	0.004
I38 Endocarditis, valve unspecified	0.004	0.996	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.004	0.996	0.000
J95.0 Tracheostomy malfunction	0.000	0.996	0.004
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.004	0.996	0.000
S06 Intracranial injury	0.000	0.996	0.004
I08.2 Disorders of both aortic and tricuspid valves	0.004	0.996	0.000
J96.09 Acute respiratory failure; Type unspecified	0.000	0.996	0.003
J96.01 Acute respiratory failure; Type II [hypercapnic]	0.000	0.996	0.003
J96.00 Acute respiratory failure; Type I [hypoxic]	0.000	0.996	0.003
J96.19 Chronic respiratory failure; Type unspecified	0.000	0.996	0.003
J96.11 Chronic respiratory failure; Type II [hypercapnic]	0.000	0.996	0.003
J96.10 Chronic respiratory failure; Type I [hypoxic]	0.000	0.996	0.003
J96.99 Respiratory failure, unspecified; Type unspecified	0.000	0.996	0.003
J96.91 Respiratory failure unspecified; Type II [hypercapnic]	0.000	0.996	0.003
J96.90 Respiratory failure, unspecified; Type I [hypoxic]	0.000	0.996	0.003
S02.4 Fracture of malar and maxillary bones	0.000	0.996	0.004
N87.0 Mild cervical dysplasia	0.000	0.996	0.004
I36 Nonrheumatic tricuspid valve disorders	0.004	0.996	0.000
I09 Other rheumatic heart diseases	0.003	0.996	0.000
I08.8 Other multiple valve diseases	0.003	0.996	0.000
I05 Rheumatic mitral valve diseases	0.003	0.996	0.000
C67.4 Posterior wall of bladder	0.003	0.996	0.000
H35.0 Background retinopathy and retinal vascular changes	0.000	0.996	0.003
H35 Other retinal disorders	0.000	0.996	0.004
I08.9 Multiple valve disease, unspecified	0.003	0.996	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.997	0.003
C67 Malignant neoplasm of bladder	0.003	0.997	0.000
F20.9 Schizophrenia, unspecified	0.003	0.997	0.000
I30-I52 Other forms of heart disease	0.003	0.997	0.000
I06 Rheumatic aortic valve diseases	0.003	0.997	0.000
I44.6 Other and unspecified fascicular block	0.003	0.997	0.000
S06.3 Focal brain injury	0.000	0.997	0.003
S06.2 Diffuse brain injury	0.000	0.997	0.003
H35.3 Degeneration of macula and posterior pole	0.000	0.997	0.003
C67.9 Bladder, unspecified	0.003	0.997	0.000
F20.0 Paranoid schizophrenia	0.003	0.997	0.000
I00-I02 Acute rheumatic fever	0.003	0.997	0.000
C67.5 Bladder neck	0.003	0.997	0.000
I44 Atrioventricular and left bundle-branch block	0.003	0.997	0.000
S02 Fracture of skull and facial bones	0.000	0.997	0.003
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.997	0.003
M70.6 Trochanteric bursitis	0.003	0.997	0.000
S06.8 Other intracranial injuries	0.000	0.997	0.003
S06.4 Epidural haemorrhage	0.000	0.997	0.003
C67.6 Ureteric orifice	0.003	0.997	0.000
H35.9 Retinal disorder, unspecified	0.000	0.997	0.003
H35.4 Peripheral retinal degeneration	0.000	0.997	0.003
C67.3 Anterior wall of bladder	0.003	0.997	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.003	0.997	0.000
I44.7 Left bundle-branch block, unspecified	0.003	0.997	0.000
I05.0 Mitral stenosis	0.003	0.997	0.000
I09.9 Rheumatic heart disease, unspecified	0.003	0.997	0.000
S02.5 Fracture of tooth	0.000	0.997	0.003
I33 Acute and subacute endocarditis	0.003	0.997	0.000
I05.9 Mitral valve disease, unspecified	0.003	0.997	0.000
I44.3 Other and unspecified atrioventricular block	0.003	0.997	0.000
S06.9 Intracranial injury, unspecified	0.000	0.997	0.003
S06.7 Intracranial injury with prolonged coma	0.000	0.997	0.003
S06.1 Traumatic cerebral oedema	0.000	0.997	0.003
S06.0 Concussion	0.000	0.997	0.003
S02.2 Fracture of nasal bones	0.000	0.997	0.003
S02.50 Fracture of tooth (closed)	0.000	0.997	0.003
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.997	0.003
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.997	0.003
F20 Schizophrenia	0.003	0.997	0.000
I42 Cardiomyopathy	0.003	0.997	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.997	0.003
I07 Rheumatic tricuspid valve diseases	0.003	0.997	0.000
C67.2 Lateral wall of bladder	0.003	0.997	0.000
I37 Pulmonary valve disorders	0.003	0.997	0.000
S52.10 Fracture of upper end of radius (closed)	0.003	0.997	0.000
I45 Other conduction disorders	0.003	0.997	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.003	0.997	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.003	0.997	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.003	0.997	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.003	0.997	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.003	0.997	0.000
C67.0 Trigone of bladder	0.003	0.997	0.000
I09.8 Other specified rheumatic heart diseases	0.003	0.997	0.000
I09.2 Chronic rheumatic pericarditis	0.003	0.997	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.003	0.997	0.000
I09.0 Rheumatic myocarditis	0.003	0.997	0.000
I42.2 Other hypertrophic cardiomyopathy	0.003	0.997	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.997	0.003
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.997	0.003
I05.8 Other mitral valve diseases	0.003	0.997	0.000
H35.1 Retinopathy of prematurity	0.000	0.997	0.003
I45.9 Conduction disorder, unspecified	0.003	0.997	0.000
S02.0 Fracture of vault of skull	0.000	0.997	0.003
L57 Skin changes due to chronic exposure to nonionising radiation	0.003	0.997	0.000
I47.2 Ventricular tachycardia	0.003	0.997	0.000
I33.9 Acute endocarditis, unspecified	0.003	0.997	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.997	0.003
C67.8 Overlapping lesion of bladder	0.003	0.997	0.000
C67.7 Urachus	0.003	0.997	0.000
S02.1 Fracture of base of skull	0.000	0.997	0.003
I05.1 Rheumatic mitral insufficiency	0.003	0.997	0.000
I52 Other heart disorders in diseases classified elsewhere	0.003	0.997	0.000
I48 Atrial fibrillation and flutter	0.003	0.997	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.003	0.997	0.000
I41 Myocarditis in diseases classified elsewhere	0.003	0.997	0.000
I40 Acute myocarditis	0.003	0.997	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.003	0.997	0.000
I32 Pericarditis in diseases classified elsewhere	0.003	0.997	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.997	0.003
I45.5 Other specified heart block	0.003	0.997	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.002	0.997	0.000
I06.8 Other rheumatic aortic valve diseases	0.002	0.997	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.002	0.997	0.000
I06.1 Rheumatic aortic insufficiency	0.002	0.997	0.000
I06.0 Rheumatic aortic stenosis	0.002	0.997	0.000
H35.2 Other proliferative retinopathy	0.000	0.997	0.003
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.997	0.002
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.997	0.002
I42.9 Cardiomyopathy, unspecified	0.003	0.997	0.000
N13 Obstructive and reflux uropathy	0.000	0.997	0.003
H35.5 Hereditary retinal dystrophy	0.000	0.997	0.003
S02.3 Fracture of orbital floor	0.000	0.997	0.003
I02 Rheumatic chorea	0.002	0.997	0.000
I01 Rheumatic fever with heart involvement	0.002	0.997	0.000
I00 Rheumatic fever without mention of heart involvement	0.002	0.997	0.000
I44.5 Left posterior fascicular block	0.003	0.997	0.000
I44.4 Left anterior fascicular block	0.003	0.997	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.997	0.002
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.997	0.002
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.003	0.997	0.000
M70.69 Trochanteric bursitis-Site unspec	0.002	0.997	0.000
M70.68 Trochanteric bursitis-Other	0.002	0.997	0.000
M70.67 Trochanteric bursitis-Ankle/Foot	0.002	0.997	0.000
M70.66 Trochanteric bursitis-Lower Leg	0.002	0.997	0.000
M70.64 Trochanteric bursitis-Hand	0.002	0.997	0.000
M70.63 Trochanteric bursitis-Forearm	0.002	0.997	0.000
M70.62 Trochanteric bursitis-Upper arm	0.002	0.997	0.000
M70.61 Trochanteric bursitis-Shldr region	0.002	0.997	0.000
M70.60 Trochanteric bursitis-Mult sites	0.002	0.997	0.000
C21.1 Anal canal	0.003	0.997	0.000
S02.8 Fractures of other skull and facial bones	0.000	0.997	0.002
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.997	0.002
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.997	0.002
I37.1 Pulmonary valve insufficiency	0.002	0.997	0.000
L60.0 Ingrowing nail	0.000	0.997	0.003
I44.1 Atrioventricular block, second degree	0.003	0.997	0.000
I33.0 Acute and subacute infective endocarditis	0.002	0.997	0.000
Z99.1 Dependence on respirator	0.003	0.997	0.000
I50 Heart failure	0.003	0.997	0.000
S02.00 Fracture of vault of skull (closed)	0.000	0.997	0.002
I05.2 Mitral stenosis with insufficiency	0.002	0.997	0.000
I45.1 Other and unspecified right bundle-branch block	0.002	0.997	0.000
Z48.8 Other specified surgical follow-up care	0.002	0.997	0.000
I35 Nonrheumatic aortic valve disorders	0.002	0.997	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.002	0.998	0.000
S02.51 Fracture of tooth (open)	0.000	0.998	0.002
H35.6 Retinal haemorrhage	0.000	0.998	0.002
I42.0 Dilated cardiomyopathy	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.000	0.998	0.002
S06.01 Concussion (with open intracranial wound)	0.000	0.998	0.002
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.998	0.002
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.998	0.002
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.998	0.002
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.998	0.002
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.998	0.002
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.998	0.002
H35.7 Separation of retinal layers	0.000	0.998	0.002
I45.8 Other specified conduction disorders	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.998	0.002
S02.21 Fracture of nasal bones (open)	0.000	0.998	0.002
S06.00 Concussion (without open intracranial wound)	0.000	0.998	0.002
N13.4 Hydroureter	0.000	0.998	0.002
C77.9 Lymph node, unspecified	0.002	0.998	0.000
F20.8 Other schizophrenia	0.002	0.998	0.000
F20.6 Simple schizophrenia	0.002	0.998	0.000
F20.5 Residual schizophrenia	0.002	0.998	0.000
F20.4 Postschizophrenic depression	0.002	0.998	0.000
F20.3 Undifferentiated schizophrenia	0.002	0.998	0.000
F20.2 Catatonic schizophrenia	0.002	0.998	0.000
F20.1 Hebephrenic schizophrenia	0.002	0.998	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.002	0.998	0.000
I42.5 Other restrictive cardiomyopathy	0.002	0.998	0.000
I42.4 Endocardial fibroelastosis	0.002	0.998	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.002	0.998	0.000
I81 Portal vein thrombosis	0.002	0.998	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.002	0.998	0.000
I07.9 Tricuspid valve disease, unspecified	0.002	0.998	0.000
I07.8 Other tricuspid valve diseases	0.002	0.998	0.000
I07.2 Tricuspid stenosis with insufficiency	0.002	0.998	0.000
I07.0 Tricuspid stenosis	0.002	0.998	0.000
N13.6 Pyonephrosis	0.000	0.998	0.002
I37.9 Pulmonary valve disorder, unspecified	0.002	0.998	0.000
I37.8 Other pulmonary valve disorders	0.002	0.998	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.002	0.998	0.000
I37.0 Pulmonary valve stenosis	0.002	0.998	0.000
I47 Paroxysmal tachycardia	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.998	0.002
I45.4 Nonspecific intraventricular block	0.002	0.998	0.000
I45.0 Right fascicular block	0.002	0.998	0.000
I30 Acute pericarditis	0.002	0.998	0.000
I35.1 Aortic (valve) insufficiency	0.002	0.998	0.000
S02.6 Fracture of mandible	0.000	0.998	0.002
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.002	0.998	0.000
I08.0 Disorders of both mitral and aortic valves	0.002	0.998	0.000
S02.01 Fracture of vault of skull (open)	0.000	0.998	0.002
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.002	0.998	0.000
L57.5 Actinic granuloma	0.002	0.998	0.000
L57.4 Cutis laxa senilis	0.002	0.998	0.000
L57.3 Poikiloderma of Civatte	0.002	0.998	0.000
L57.2 Cutis rhomboidalis nuchae	0.002	0.998	0.000
L57.1 Actinic reticuloid	0.002	0.998	0.000
I70.0 Atherosclerosis of aorta	0.002	0.998	0.000
S02.11 Fracture of base of skull (open)	0.000	0.998	0.002
I45.2 Bifascicular block	0.002	0.998	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.002	0.998	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.002	0.998	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.002	0.998	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I40.9 Acute myocarditis, unspecified	0.002	0.998	0.000
I40.8 Other acute myocarditis	0.002	0.998	0.000
I40.1 Isolated myocarditis	0.002	0.998	0.000
I40.0 Infective myocarditis	0.002	0.998	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.002	0.998	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.002	0.998	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.002	0.998	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.002	0.998	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.002	0.998	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.002	0.998	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.002	0.998	0.000
I48.4 Atypical atrial flutter	0.002	0.998	0.000
I48.3 Typical atrial flutter	0.002	0.998	0.000
I48.2 Chronic atrial fibrillation	0.002	0.998	0.000
I48.1 Persistent atrial fibrillation	0.002	0.998	0.000
I48.0 Paroxysmal atrial fibrillation	0.002	0.998	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.002	0.998	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.002	0.998	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations