TreeWAS – Variant ID: rs12189871

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M07.39 Other psoriatic arthropathies (Site unspecified)	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
M07.3 Other psoriatic arthropathies	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000	0.000
L40.0 Psoriasis vulgaris	1.000	0.000	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E03 Other hypothyroidism	0.000	0.001	0.999
K50-K52 Noninfective enteritis and colitis	0.999	0.001	0.000
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
K50 Crohn's disease [regional enteritis]	0.999	0.001	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.002	0.998
K83 Other diseases of biliary tract	0.998	0.002	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003	0.000
M07 Psoriatic and enteropathic arthropathies	0.997	0.003	0.000
K80 Cholelithiasis	0.995	0.005	0.000
K50.0 Crohn's disease of small intestine	0.995	0.005	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.995	0.005	0.000
M05-M14 Inflammatory polyarthropathies	0.994	0.006	0.000
L40-L45 Papulosquamous disorders	0.994	0.006	0.000
M45-M49 Spondylopathies	0.992	0.008	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.008	0.992
K70-K77 Diseases of liver	0.992	0.008	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.991	0.009	0.000
M47.8 Other spondylosis	0.990	0.010	0.000
M47 Spondylosis	0.990	0.010	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.011	0.989
Chapter II Neoplasms	0.989	0.011	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.985	0.015	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.980	0.020	0.000
Chapter I Certain infectious and parasitic diseases	0.978	0.022	0.000
K83.1 Obstruction of bile duct	0.977	0.023	0.000
C34 Malignant neoplasm of bronchus and lung	0.976	0.024	0.000
Chapter XX External causes of morbidity and mortality	0.975	0.025	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.966	0.034	0.000
M47.82 Other spondylosis (Cervical region)	0.964	0.036	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.958	0.042	0.000
E07 Other disorders of thyroid	0.000	0.043	0.957
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.953	0.047	0.000
C34.9 Bronchus or lung, unspecified	0.950	0.050	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.946	0.054	0.000
K50.8 Other Crohn's disease	0.941	0.059	0.000
K83.8 Other specified diseases of biliary tract	0.940	0.060	0.000
K72 Hepatic failure, not elsewhere classified	0.933	0.067	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.069	0.931
C50-C50 Malignant neoplasm of breast	0.926	0.074	0.000
K50.9 Crohn's disease, unspecified	0.925	0.075	0.000
K74 Fibrosis and cirrhosis of liver	0.925	0.075	0.000
S80-S89 Injuries to the knee and lower leg	0.924	0.076	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.921	0.079	0.000
D00-D09 In situ neoplasms	0.917	0.083	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.913	0.087	0.000
A00-A09 Intestinal infectious diseases	0.909	0.091	0.000
W20-W49 Exposure to inanimate mechanical forces	0.905	0.095	0.000
M47.89 Other spondylosis (Site unspecified)	0.902	0.098	0.000
K74.0 Hepatic fibrosis	0.893	0.107	0.000
C32 Malignant neoplasm of larynx	0.890	0.110	0.000
K72.9 Hepatic failure, unspecified	0.888	0.112	0.000
S80 Superficial injury of lower leg	0.887	0.113	0.000
K75 Other inflammatory liver diseases	0.886	0.114	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.885	0.115	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.882	0.118	0.000
C50 Malignant neoplasm of breast	0.881	0.119	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.878	0.122	0.000
Q60-Q64 Congenital malformations of the urinary system	0.876	0.124	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.869	0.131	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.867	0.133	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.866	0.134	0.000
A04 Other bacterial intestinal infections	0.864	0.136	0.000
L40.8 Other psoriasis	0.858	0.142	0.000
L40.1 Generalised pustular psoriasis	0.854	0.146	0.000
W44 Foreign body entering into or through eye or natural orifice	0.852	0.148	0.000
X60-X84 Intentional self-harm	0.847	0.153	0.000
K80.4 Calculus of bile duct with cholecystitis	0.845	0.155	0.000
C34.1 Upper lobe, bronchus or lung	0.844	0.156	0.000
A80-A89 Viral infections of the central nervous system	0.838	0.162	0.000
Q21 Congenital malformations of cardiac septa	0.837	0.163	0.000
L40.4 Guttate psoriasis	0.837	0.163	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.835	0.165	0.000
B65-B83 Helminthiases	0.835	0.165	0.000
K81 Cholecystitis	0.834	0.166	0.000
D05 Carcinoma in situ of breast	0.831	0.169	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.828	0.171	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.828	0.172	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.825	0.175	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.824	0.176	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.823	0.177	0.000
K83.0 Cholangitis	0.823	0.177	0.000
S80.9 Superficial injury of lower leg, unspecified	0.820	0.180	0.000
M91-M94 Chondropathies	0.820	0.180	0.000
B15-B19 Viral hepatitis	0.819	0.181	0.000
S90-S99 Injuries to the ankle and foot	0.817	0.183	0.000
W44.0 Home	0.813	0.187	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.808	0.192	0.000
W75-W84 Other accidental threats to breathing	0.805	0.195	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.804	0.196	0.000
K75.8 Other specified inflammatory liver diseases	0.801	0.199	0.000
C34.2 Middle lobe, bronchus or lung	0.800	0.200	0.000
X50-X57 Overexertion, travel and privation	0.798	0.202	0.000
K83.3 Fistula of bile duct	0.795	0.205	0.000
Q21.1 Atrial septal defect	0.795	0.205	0.000
C32.0 Glottis	0.795	0.205	0.000
D04 Carcinoma in situ of skin	0.793	0.207	0.000
T88.4 Failed or difficult intubation	0.788	0.212	0.000
K71 Toxic liver disease	0.784	0.216	0.000
V40-V49 Car occupant injured in transport accident	0.784	0.216	0.000
S10-S19 Injuries to the neck	0.782	0.218	0.000
M60-M63 Disorders of muscles	0.779	0.221	0.000
S80.8 Other superficial injuries of lower leg	0.778	0.222	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.776	0.224	0.000
A15-A19 Tuberculosis	0.776	0.224	0.000
B50-B64 Protozoal diseases	0.776	0.224	0.000
S81 Open wound of lower leg	0.775	0.225	0.000
C50.2 Upper-inner quadrant of breast	0.774	0.226	0.000
C50.5 Lower-outer quadrant of breast	0.773	0.227	0.000
W50-W64 Exposure to animate mechanical forces	0.771	0.229	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.770	0.230	0.000
S70-S79 Injuries to the hip and thigh	0.765	0.235	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.762	0.238	0.000
C50.4 Upper-outer quadrant of breast	0.761	0.239	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.760	0.240	0.000
W22 Striking against or struck by other objects	0.759	0.241	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.759	0.241	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.757	0.243	0.000
Q61 Cystic kidney disease	0.757	0.243	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.757	0.243	0.000
C37 Malignant neoplasm of thymus	0.756	0.244	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.754	0.246	0.000
K75.9 Inflammatory liver disease, unspecified	0.754	0.246	0.000
B00 Herpesviral [herpes simplex] infections	0.754	0.246	0.000
C34.0 Main bronchus	0.752	0.248	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.752	0.248	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.752	0.248	0.000
M46 Other inflammatory spondylopathies	0.750	0.250	0.000
M47.2 Other spondylosis with radiculopathy	0.750	0.250	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.749	0.251	0.000
K83.9 Disease of biliary tract, unspecified	0.748	0.252	0.000
S92 Fracture of foot, except ankle	0.748	0.252	0.000
A04.5 Campylobacter enteritis	0.747	0.253	0.000
K52 Other non-infective gastro-enteritis and colitis	0.746	0.254	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.745	0.254	0.000
V80-V89 Other land transport accidents	0.745	0.255	0.000
X10-X19 Contact with heat and hot substances	0.744	0.256	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.743	0.257	0.000
B25-B34 Other viral diseases	0.742	0.258	0.000
K76 Other diseases of liver	0.742	0.258	0.000
K57 Diverticular disease of intestine	0.742	0.258	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.741	0.259	0.000
C79 Secondary malignant neoplasm of other sites	0.740	0.260	0.000
D06 Carcinoma in situ of cervix uteri	0.740	0.260	0.000
L10-L14 Bullous disorders	0.739	0.261	0.000
K55-K64 Other diseases of intestines	0.739	0.261	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.738	0.262	0.000
A87 Viral meningitis	0.737	0.263	0.000
K81.0 Acute cholecystitis	0.736	0.264	0.000
T87 Complications peculiar to reattachment and amputation	0.736	0.264	0.000
M80-M85 Disorders of bone density and structure	0.735	0.265	0.000
B80 Enterobiasis	0.733	0.267	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.733	0.267	0.000
M00-M03 Infectious arthropathies	0.733	0.267	0.000
B35-B49 Mycoses	0.732	0.268	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.732	0.268	0.000
C50.1 Central portion of breast	0.730	0.270	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.726	0.274	0.000
M70-M79 Other soft tissue disorders	0.725	0.275	0.000
A02 Other Salmonella infections	0.724	0.276	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.724	0.276	0.000
M49 Spondylopathies in diseases classified elsewhere	0.723	0.276	0.000
T88.5 Other complications of anaesthesia	0.723	0.277	0.000
A65-A69 Other spirochaetal diseases	0.721	0.279	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.721	0.279	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.720	0.280	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.719	0.281	0.000
S86 Injury of muscle and tendon at lower leg level	0.718	0.281	0.000
Q21.0 Ventricular septal defect	0.718	0.282	0.000
M07.38 Other psoriatic arthropathies (Other)	0.717	0.283	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.717	0.283	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.717	0.283	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E03.5 Myxoedema coma	0.000	0.284	0.716
E03.4 Atrophy of thyroid (acquired)	0.000	0.284	0.716
E03.3 Postinfectious hypothyroidism	0.000	0.284	0.716
E03.1 Congenital hypothyroidism without goitre	0.000	0.284	0.716
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.284	0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.284	0.716
E00 Congenital iodine-deficiency syndrome	0.000	0.284	0.716
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.284	0.716
E05.8 Other thyrotoxicosis	0.000	0.284	0.716
E05.5 Thyroid crisis or storm	0.000	0.284	0.716
E05.4 Thyrotoxicosis factitia	0.000	0.284	0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.284	0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.284	0.716
L42 Pityriasis rosea	0.716	0.284	0.000
K83.5 Biliary cyst	0.715	0.285	0.000
K83.4 Spasm of sphincter of Oddi	0.715	0.285	0.000
K83.2 Perforation of bile duct	0.715	0.285	0.000
C32.9 Larynx, unspecified	0.715	0.285	0.000
M07.6 Other enteropathic arthropathies	0.714	0.285	0.000
M07.5 Arthropathy in ulcerative colitis	0.714	0.285	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.714	0.285	0.000
M07.2 Psoriatic spondylitis	0.714	0.285	0.000
M07.1 Arthritis mutilans	0.714	0.285	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.714	0.285	0.000
K80.3 Calculus of bile duct with cholangitis	0.713	0.287	0.000
C05 Malignant neoplasm of palate	0.713	0.287	0.000
M12 Other specific arthropathies	0.713	0.287	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.713	0.287	0.000
M08 Juvenile arthritis	0.713	0.287	0.000
L44 Other papulosquamous disorders	0.713	0.287	0.000
L41 Parapsoriasis	0.713	0.287	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.713	0.287	0.000
Chapter XXII Codes for special purposes	0.712	0.288	0.000
K77 Liver disorders in diseases classified elsewhere	0.711	0.289	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.710	0.290	0.000
M47.84 Other spondylosis (Thoracic region)	0.710	0.290	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.710	0.290	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.710	0.290	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.710	0.290	0.000
C11 Malignant neoplasm of nasopharynx	0.710	0.290	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.709	0.291	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.709	0.291	0.000
K74.6 Other and unspecified cirrhosis of liver	0.709	0.291	0.000
Q64 Other congenital malformations of urinary system	0.707	0.293	0.000
Q80-Q89 Other congenital malformations	0.707	0.293	0.000
M94 Other disorders of cartilage	0.707	0.293	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.706	0.294	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.706	0.294	0.000
C31 Malignant neoplasm of accessory sinuses	0.706	0.294	0.000
C33 Malignant neoplasm of trachea	0.706	0.294	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.705	0.295	0.000
X78 Intentional self-harm by sharp object	0.703	0.297	0.000
M11 Other crystal arthropathies	0.703	0.297	0.000
V20-V29 Motorcycle rider injured in transport accident	0.703	0.297	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.702	0.298	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.701	0.299	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.701	0.299	0.000
A75-A79 Rickettsioses	0.701	0.299	0.000
A70-A74 Other diseases caused by chlamydiae	0.701	0.299	0.000
A20-A28 Certain zoonotic bacterial diseases	0.701	0.299	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.299	0.700
C34.8 Overlapping lesion of bronchus and lung	0.700	0.300	0.000
C34.3 Lower lobe, bronchus or lung	0.700	0.300	0.000
Y35-Y36 Legal intervention and operations of war	0.699	0.301	0.000
Y10-Y34 Event of undetermined intent	0.699	0.301	0.000
X85-X99 Assault	0.699	0.301	0.000
X30-X39 Exposure to forces of nature	0.699	0.301	0.000
X00-X09 Exposure to smoke, fire and flames	0.699	0.301	0.000
W65-W74 Accidental drowning and submersion	0.699	0.301	0.000
V98-V99 Other and unspecified transport accidents	0.699	0.301	0.000
V95-V97 Air and space transport accidents	0.699	0.301	0.000
V90-V94 Water transport accidents	0.699	0.301	0.000
V70-V79 Bus occupant injured in transport accident	0.699	0.301	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.699	0.301	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.699	0.301	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.699	0.301	0.000
V01-V09 Pedestrian injured in transport accident	0.699	0.301	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.699	0.301	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.699	0.301	0.000
T21 Burn and corrosion of trunk	0.697	0.303	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.697	0.303	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.697	0.303	0.000
T17 Foreign body in respiratory tract	0.696	0.304	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.695	0.305	0.000
L50-L54 Urticaria and erythema	0.695	0.305	0.000
C04 Malignant neoplasm of floor of mouth	0.693	0.306	0.000
M14 Arthropathies in other diseases classified elsewhere	0.692	0.308	0.000
K85 Acute pancreatitis	0.692	0.308	0.000
W27 Contact with nonpowered hand tool	0.692	0.308	0.000
T18 Foreign body in alimentary tract	0.691	0.309	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.690	0.310	0.000
S79 Other and unspecified injuries of hip and thigh	0.689	0.311	0.000
A04.8 Other specified bacterial intestinal infections	0.688	0.312	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.687	0.313	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.687	0.313	0.000
Q35-Q37 Cleft lip and cleft palate	0.687	0.313	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.687	0.313	0.000
K72.0 Acute and subacute hepatic failure	0.687	0.313	0.000
E07.1 Dyshormogenetic goitre	0.000	0.313	0.686
E07.0 Hypersecretion of calcitonin	0.000	0.313	0.686
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.685	0.315	0.000
C50.9 Breast, unspecified	0.685	0.315	0.000
T33-T35 Frostbite	0.684	0.316	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.684	0.316	0.000
T00-T07 Injuries involving multiple body regions	0.684	0.316	0.000
K50.1 Crohn's disease of large intestine	0.683	0.317	0.000
W84 Unspecified threat to breathing	0.683	0.317	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.683	0.317	0.000
B99-B99 Other infectious diseases	0.681	0.319	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.680	0.320	0.000
C73 Malignant neoplasm of thyroid gland	0.680	0.320	0.000
K81.1 Chronic cholecystitis	0.679	0.321	0.000
M86-M90 Other osteopathies	0.678	0.322	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.678	0.322	0.000
M84 Disorders of continuity of bone	0.678	0.322	0.000
W45 Foreign body or object entering through skin	0.678	0.322	0.000
D05.1 Intraductal carcinoma in situ	0.678	0.322	0.000
S81.8 Open wound of other parts of lower leg	0.677	0.323	0.000
C12 Malignant neoplasm of pyriform sinus	0.677	0.323	0.000
X65 Intentional self-poisoning by and exposure to alcohol	0.677	0.323	0.000
B17 Other acute viral hepatitis	0.676	0.324	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.676	0.324	0.000
X50 Overexertion and strenuous or repetitive movements	0.675	0.325	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.675	0.325	0.000
M48 Other spondylopathies	0.674	0.326	0.000
K73 Chronic hepatitis, not elsewhere classified	0.674	0.326	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.673	0.327	0.000
S82 Fracture of lower leg, including ankle	0.672	0.328	0.000
B18 Chronic viral hepatitis	0.671	0.329	0.000
E06 Thyroiditis	0.000	0.331	0.669
Q60 Renal agenesis and other reduction defects of kidney	0.669	0.331	0.000
K72.1 Chronic hepatic failure	0.669	0.331	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.669	0.331	0.000
B01 Varicella [chickenpox]	0.667	0.333	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.666	0.334	0.000
D05.7 Other carcinoma in situ of breast	0.666	0.334	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.665	0.335	0.000
A87.9 Viral meningitis, unspecified	0.665	0.335	0.000
K58 Irritable bowel syndrome	0.664	0.336	0.000
Q50-Q56 Congenital malformations of genital organs	0.663	0.337	0.000
K74.4 Secondary biliary cirrhosis	0.663	0.337	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.663	0.337	0.000
K74.1 Hepatic sclerosis	0.663	0.337	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.663	0.337	0.000
S88 Traumatic amputation of lower leg	0.662	0.337	0.000
S87 Crushing injury of lower leg	0.662	0.337	0.000
S85 Injury of blood vessels at lower leg level	0.662	0.337	0.000
S84 Injury of nerves at lower leg level	0.662	0.337	0.000
Y00-Y09 Assault	0.662	0.338	0.000
Q00-Q07 Congenital malformations of the nervous system	0.661	0.339	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.660	0.340	0.000
S92.0 Fracture of calcaneus	0.660	0.340	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.660	0.340	0.000
V10-V19 Pedal cyclist injured in transport accident	0.659	0.341	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.658	0.342	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.657	0.343	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.657	0.343	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.657	0.343	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.656	0.344	0.000
S97 Crushing injury of ankle and foot	0.656	0.344	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.655	0.345	0.000
E07.8 Other specified disorders of thyroid	0.000	0.345	0.654
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.654	0.346	0.000
Y43 Primarily systemic agents	0.654	0.346	0.000
A07 Other protozoal intestinal diseases	0.653	0.347	0.000
A06 Amoebiasis	0.652	0.348	0.000
A05 Other bacterial foodborne intoxications	0.652	0.348	0.000
A03 Shigellosis	0.652	0.348	0.000
A01 Typhoid and paratyphoid fevers	0.652	0.348	0.000
A00 Cholera	0.652	0.348	0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.652	0.348	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.651	0.349	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.650	0.349	0.000
C01 Malignant neoplasm of base of tongue	0.650	0.350	0.000
B37 Candidiasis	0.649	0.351	0.000
W46 Contact with hypodermic needle	0.649	0.351	0.000
W43 Exposure to vibration	0.649	0.351	0.000
W42 Exposure to noise	0.649	0.351	0.000
W41 Exposure to high-pressure jet	0.649	0.351	0.000
W40 Explosion of other materials	0.649	0.351	0.000
W39 Discharge of firework	0.649	0.351	0.000
W38 Explosion and rupture of other specified pressurised devices	0.649	0.351	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.649	0.351	0.000
W36 Explosion and rupture of gas cylinder	0.649	0.351	0.000
W35 Explosion and rupture of boiler	0.649	0.351	0.000
W34 Discharge from other and unspecified firearms	0.649	0.351	0.000
W33 Rifle, shotgun and larger firearm discharge	0.649	0.351	0.000
W32 Handgun discharge	0.649	0.351	0.000
W31 Contact with other and unspecified machinery	0.649	0.351	0.000
W30 Contact with agricultural machinery	0.649	0.351	0.000
W28 Contact with powered lawn mower	0.649	0.351	0.000
W26 Contact with knife, sword or dagger	0.649	0.351	0.000
A04.9 Bacterial intestinal infection, unspecified	0.649	0.351	0.000
M76 Enthesopathies of lower limb, excluding foot	0.647	0.352	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.647	0.353	0.000
B00.1 Herpesviral vesicular dermatitis	0.645	0.355	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.644	0.356	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.644	0.356	0.000
C64-C68 Malignant neoplasms of urinary tract	0.642	0.358	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.642	0.358	0.000
K74.5 Biliary cirrhosis, unspecified	0.641	0.359	0.000
Q61.3 Polycystic kidney, unspecified	0.640	0.360	0.000
D04.3 Skin of other and unspecified parts of face	0.639	0.361	0.000
C32.8 Overlapping lesion of larynx	0.638	0.362	0.000
C32.3 Laryngeal cartilage	0.638	0.362	0.000
C32.2 Subglottis	0.638	0.362	0.000
W20 Struck by thrown, projected or falling object	0.638	0.362	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.637	0.363	0.000
C74 Malignant neoplasm of adrenal gland	0.637	0.363	0.000
X20-X29 Contact with venomous animals and plants	0.636	0.363	0.000
D55-D59 Haemolytic anaemias	0.636	0.364	0.000
S80.7 Multiple superficial injuries of lower leg	0.636	0.364	0.000
K71.0 Toxic liver disease with cholestasis	0.636	0.364	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.636	0.364	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.636	0.364	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.635	0.365	0.000
K75.2 Nonspecific reactive hepatitis	0.635	0.365	0.000
K75.1 Phlebitis of portal vein	0.635	0.365	0.000
S79.9 Unspecified injury of hip and thigh	0.635	0.365	0.000
M77 Other enthesopathies	0.635	0.365	0.000
T88.9 Complication of surgical and medical care, unspecified	0.634	0.366	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.634	0.366	0.000
T88.2 Shock due to anaesthesia	0.634	0.366	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.634	0.366	0.000
T88.0 Infection following immunisation	0.634	0.366	0.000
D37.1 Stomach	0.634	0.366	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.634	0.366	0.000
D04.6 Skin of upper limb, including shoulder	0.633	0.367	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.633	0.367	0.000
Q25 Congenital malformations of great arteries	0.633	0.367	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.632	0.368	0.000
D37.5 Rectum	0.632	0.368	0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.631	0.369	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.631	0.369	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.630	0.370	0.000
E03.8 Other specified hypothyroidism	0.000	0.370	0.630
C13 Malignant neoplasm of hypopharynx	0.629	0.371	0.000
C10 Malignant neoplasm of oropharynx	0.629	0.371	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.629	0.371	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.629	0.371	0.000
C03 Malignant neoplasm of gum	0.629	0.371	0.000
C00 Malignant neoplasm of lip	0.629	0.371	0.000
C07 Malignant neoplasm of parotid gland	0.629	0.371	0.000
S14 Injury of nerves and spinal cord at neck level	0.629	0.371	0.000
C32.1 Supraglottis	0.628	0.372	0.000
C50.6 Axillary tail of breast	0.626	0.374	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.626	0.374	0.000
B34 Viral infection of unspecified site	0.625	0.375	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.624	0.376	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.623	0.377	0.000
W25 Contact with sharp glass	0.623	0.377	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.623	0.377	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.623	0.377	0.000
S40-S49 Injuries to the shoulder and upper arm	0.622	0.377	0.000
M62 Other disorders of muscle	0.622	0.377	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.622	0.378	0.000
Q26 Congenital malformations of great veins	0.621	0.378	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.621	0.378	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.621	0.378	0.000
D04.4 Skin of scalp and neck	0.621	0.379	0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus	0.621	0.379	0.000
M47.1 Other spondylosis with myelopathy	0.620	0.380	0.000
K76.7 Hepatorenal syndrome	0.620	0.380	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.619	0.381	0.000
A04.4 Other intestinal Escherichia coli infections	0.619	0.381	0.000
A04.3 Enterohaemorrhagic Escherichia coli infection	0.619	0.381	0.000
A04.2 Enteroinvasive Escherichia coli infection	0.619	0.381	0.000
A04.1 Enterotoxigenic Escherichia coli infection	0.619	0.381	0.000
A04.0 Enteropathogenic Escherichia coli infection	0.619	0.381	0.000
Y43.3 Other antineoplastic drugs	0.616	0.384	0.000
K82 Other diseases of gallbladder	0.615	0.384	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.615	0.385	0.000
D07.1 Vulva	0.615	0.385	0.000
K57.0 Diverticular disease of small intestine with perforation and abscess	0.614	0.386	0.000
D06.9 Cervix, unspecified	0.614	0.386	0.000
K75.0 Abscess of liver	0.612	0.387	0.000
S81.0 Open wound of knee	0.612	0.388	0.000
D60-D64 Aplastic and other anaemias	0.611	0.389	0.000
W44.9 Unspecified place	0.610	0.389	0.000
W44.5 Trade and service area	0.610	0.389	0.000
W44.8 Other specified place	0.610	0.389	0.000
W44.7 Farm	0.610	0.389	0.000
W44.6 Industrial and construction area	0.610	0.389	0.000
W44.4 Street and highway	0.610	0.389	0.000
W44.3 Sports and athletics area	0.610	0.389	0.000
W44.2 School, other institution and public administrative area	0.610	0.389	0.000
W44.1 Residential institution	0.610	0.389	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.610	0.390	0.000
M71 Other bursopathies	0.610	0.390	0.000
W22.2 School, other institution and public administrative area	0.609	0.391	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.609	0.391	0.000
W22.9 Unspecified place	0.609	0.391	0.000
Q61.0 Congenital single renal cyst	0.608	0.392	0.000
X84 Intentional self-harm by unspecified means	0.608	0.392	0.000
X83 Intentional self-harm by other specified means	0.608	0.392	0.000
X82 Intentional self-harm by crashing of motor vehicle	0.608	0.392	0.000
X81 Intentional self-harm by jumping or lying before moving object	0.608	0.392	0.000
X80 Intentional self-harm by jumping from a high place	0.608	0.392	0.000
X79 Intentional self-harm by blunt object	0.608	0.392	0.000
X77 Intentional self-harm by steam, hot vapours and hot objects	0.608	0.392	0.000
X76 Intentional self-harm by smoke, fire and flames	0.608	0.392	0.000
X75 Intentional self-harm by explosive material	0.608	0.392	0.000
X74 Intentional self-harm by other and unspecified firearm discharge	0.608	0.392	0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.608	0.392	0.000
X72 Intentional self-harm by handgun discharge	0.608	0.392	0.000
X71 Intentional self-harm by drowning and submersion	0.608	0.392	0.000
X70 Intentional self-harm by hanging, strangulation and suffocation	0.608	0.392	0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.608	0.392	0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.608	0.392	0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.608	0.392	0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.608	0.392	0.000
S92.5 Fracture of other toe	0.606	0.394	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.606	0.394	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations