TreeWAS – Variant ID: rs12205572

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter V Mental and behavioural disorders	0.999	0.001
F10 Mental and behavioural disorders due to use of alcohol	0.999	0.001
# Top node	0.999	0.001
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.999	0.001
S00-S09 Injuries to the head	0.998	0.002
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.995	0.005
S50-S59 Injuries to the elbow and forearm	0.986	0.014
Chapter VI Diseases of the nervous system	0.985	0.015
F30-F39 Mood [affective] disorders	0.983	0.017
F10.0 Acute intoxication	0.981	0.019
M20-M25 Other joint disorders	0.979	0.021
F31 Bipolar affective disorder	0.977	0.023
S20-S29 Injuries to the thorax	0.976	0.024
M25 Other joint disorders, not elsewhere classified	0.974	0.026
S01 Open wound of head	0.968	0.032
S00 Superficial injury of head	0.965	0.035
M80-M85 Disorders of bone density and structure	0.962	0.038
G90-G99 Other disorders of the nervous system	0.957	0.043
F10.2 Dependence syndrome	0.956	0.044
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.947	0.053
F31.9 Bipolar affective disorder, unspecified	0.944	0.056
M45-M49 Spondylopathies	0.941	0.059
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.939	0.061
M25.4 Effusion of joint	0.937	0.063
M25.7 Osteophyte	0.932	0.068
F10.1 Harmful use	0.929	0.071
M25.77 Osteophyte (Ankle and foot)	0.926	0.074
S80-S89 Injuries to the knee and lower leg	0.921	0.079
M80 Osteoporosis with pathological fracture	0.920	0.080
S29 Other and unspecified injuries of thorax	0.916	0.084
S50 Superficial injury of forearm	0.906	0.094
S01.8 Open wound of other parts of head	0.905	0.095
S06 Intracranial injury	0.904	0.096
M47 Spondylosis	0.902	0.098
M80.9 Unspecified osteoporosis with pathological fracture	0.893	0.107
Chapter XX External causes of morbidity and mortality	0.881	0.119
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.876	0.124
S51 Open wound of forearm	0.876	0.124
S29.9 Unspecified injury of thorax	0.873	0.127
M47.9 Spondylosis, unspecified	0.873	0.127
M25.46 Effusion of joint (Lower leg)	0.872	0.128
S80 Superficial injury of lower leg	0.871	0.129
G80-G83 Cerebral palsy and other paralytic syndromes	0.868	0.132
F10.3 Withdrawal state	0.866	0.134
Chapter I Certain infectious and parasitic diseases	0.865	0.135
F60-F69 Disorders of adult personality and behaviour	0.861	0.139
S22 Fracture of rib(s), sternum and thoracic spine	0.859	0.141
T91 Sequelae of injuries of neck and trunk	0.858	0.142
Chapter XV Pregnancy, childbirth and the puerperium	0.857	0.143
M60-M63 Disorders of muscles	0.855	0.145
S52 Fracture of forearm	0.854	0.146
G62 Other polyneuropathies	0.850	0.150
M25.5 Pain in joint	0.850	0.150
S00.9 Superficial injury of head, part unspecified	0.848	0.152
S01.0 Open wound of scalp	0.847	0.153
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.843	0.157
G95 Other diseases of spinal cord	0.840	0.160
M84 Disorders of continuity of bone	0.839	0.161
T98 Sequelae of other and unspecified effects of external causes	0.838	0.162
S00.1 Contusion of eyelid and periocular area	0.837	0.163
F10.6 Amnesic syndrome	0.835	0.165
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.833	0.167
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.831	0.169
T79-T79 Certain early complications of trauma	0.831	0.169
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.825	0.175
S10-S19 Injuries to the neck	0.823	0.177
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.823	0.177
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.820	0.180
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.818	0.182
G91 Hydrocephalus	0.818	0.182
S51.8 Open wound of other parts of forearm	0.817	0.183
M33 Dermatopolymyositis	0.816	0.184
S01.4 Open wound of cheek and temporomandibular area	0.815	0.185
O42 Premature rupture of membranes	0.815	0.185
S01.9 Open wound of head, part unspecified	0.807	0.193
G63 Polyneuropathy in diseases classified elsewhere	0.806	0.194
M35 Other systemic involvement of connective tissue	0.804	0.196
S80.9 Superficial injury of lower leg, unspecified	0.804	0.196
S27 Injury of other and unspecified intrathoracic organs	0.802	0.198
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.800	0.199
G62.9 Polyneuropathy, unspecified	0.797	0.203
M25.55 Pain in joint (Pelvic region and thigh)	0.794	0.206
F10.9 Unspecified mental and behavioural disorder	0.792	0.208
G35-G37 Demyelinating diseases of the central nervous system	0.791	0.209
S00.7 Multiple superficial injuries of head	0.790	0.210
T20-T25 Burns and corrosions of external body surface, specified by site	0.790	0.210
G83 Other paralytic syndromes	0.787	0.213
G90 Disorders of autonomic nervous system	0.786	0.213
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.784	0.216
G96 Other disorders of central nervous system	0.784	0.216
S90-S99 Injuries to the ankle and foot	0.783	0.217
F10.5 Psychotic disorder	0.783	0.217
M25.43 Effusion of joint (Forearm)	0.781	0.219
M25.0 Haemarthrosis	0.779	0.221
S50.9 Superficial injury of forearm, unspecified	0.776	0.224
T36-T50 Poisoning by drugs, medicaments and biological substances	0.776	0.224
G93 Other disorders of brain	0.775	0.225
S59 Other and unspecified injuries of forearm	0.774	0.226
S05 Injury of eye and orbit	0.773	0.227
W20-W49 Exposure to inanimate mechanical forces	0.773	0.227
S00.5 Superficial injury of lip and oral cavity	0.772	0.228
Chapter XXII Codes for special purposes	0.771	0.229
M47.2 Other spondylosis with radiculopathy	0.771	0.229
S06.6 Traumatic subarachnoid haemorrhage	0.770	0.230
M70-M79 Other soft tissue disorders	0.769	0.231
O42.9 Premature rupture of membranes, unspecified	0.766	0.234
S50.0 Contusion of elbow	0.765	0.235
F60 Specific personality disorders	0.762	0.238
S52.1 Fracture of upper end of radius	0.760	0.240
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.760	0.240
M25.47 Effusion of joint (Ankle and foot)	0.757	0.243
M21 Other acquired deformities of limbs	0.756	0.244
S70-S79 Injuries to the hip and thigh	0.755	0.245
T00-T07 Injuries involving multiple body regions	0.753	0.247
M25.50 Pain in joint (Multiple sites)	0.752	0.248
F99-F99 Unspecified mental disorder	0.749	0.251
G94 Other disorders of brain in diseases classified elsewhere	0.749	0.251
S00.3 Superficial injury of nose	0.747	0.253
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.747	0.253
G00-G09 Inflammatory diseases of the central nervous system	0.747	0.253
S80.8 Other superficial injuries of lower leg	0.747	0.253
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.747	0.253
M32 Systemic lupus erythematosus	0.746	0.254
F80-F89 Disorders of psychological development	0.746	0.254
F31.0 Bipolar affective disorder, current episode hypomanic	0.745	0.255
F39 Unspecified mood [affective] disorder	0.743	0.256
G61 Inflammatory polyneuropathy	0.744	0.256
G95.2 Cord compression, unspecified	0.742	0.258
F10.4 Withdrawal state with delirium	0.742	0.258
S81 Open wound of lower leg	0.742	0.258
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.741	0.259
S40-S49 Injuries to the shoulder and upper arm	0.740	0.260
M00-M03 Infectious arthropathies	0.736	0.263
M62 Other disorders of muscle	0.736	0.264
S52.3 Fracture of shaft of radius	0.735	0.265
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.734	0.266
Chapter VIII Diseases of the ear and mastoid process	0.734	0.266
S09 Other and unspecified injuries of head	0.732	0.268
O44 Placenta praevia	0.731	0.268
S06.3 Focal brain injury	0.730	0.270
T90 Sequelae of injuries of head	0.730	0.270
S27.0 Traumatic pneumothorax	0.729	0.270
O32 Maternal care for known or suspected malpresentation of foetus	0.728	0.272
F11 Mental and behavioural disorders due to use of opioids	0.727	0.273
S01.1 Open wound of eyelid and periocular area	0.726	0.273
S56 Injury of muscle and tendon at forearm level	0.726	0.274
M46 Other inflammatory spondylopathies	0.725	0.275
B07 Viral warts	0.724	0.276
W50-W64 Exposure to animate mechanical forces	0.723	0.277
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.722	0.278
B02 Zoster [herpes zoster]	0.722	0.278
T91.1 Sequelae of fracture of spine	0.721	0.278
S22.4 Multiple fractures of ribs	0.721	0.279
A30-A49 Other bacterial diseases	0.720	0.280
T91.3 Sequelae of injury of spinal cord	0.719	0.281
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.716	0.283
F70-F79 Mental retardation	0.716	0.283
F10.8 Other mental and behavioural disorders	0.716	0.284
F10.7 Residual and late-onset psychotic disorder	0.716	0.284
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.716	0.284
F18 Mental and behavioural disorders due to use of volatile solvents	0.716	0.284
F16 Mental and behavioural disorders due to use of hallucinogens	0.716	0.284
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.716	0.284
F14 Mental and behavioural disorders due to use of cocaine	0.716	0.284
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.716	0.284
T94 Sequelae of injuries involving multiple and unspecified body regions	0.716	0.284
S08 Traumatic amputation of part of head	0.716	0.284
S07 Crushing injury of head	0.716	0.284
S04 Injury of cranial nerves	0.716	0.284
S03 Dislocation, sprain and strain of joints and ligaments of head	0.716	0.284
G91.9 Hydrocephalus, unspecified	0.714	0.286
F12 Mental and behavioural disorders due to use of cannabinoids	0.713	0.287
G70-G73 Diseases of myoneural junction and muscle	0.712	0.288
G63.2 Diabetic polyneuropathy	0.711	0.289
M25.9 Joint disorder, unspecified	0.711	0.289
T79 Certain early complications of trauma, not elsewhere classified	0.710	0.290
M40-M43 Deforming dorsopathies	0.710	0.290
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.707	0.293
S58 Traumatic amputation of forearm	0.707	0.293
S57 Crushing injury of forearm	0.707	0.293
S55 Injury of blood vessels at forearm level	0.707	0.293
S54 Injury of nerves at forearm level	0.707	0.293
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.707	0.293
M84.0 Malunion of fracture	0.706	0.294
F38 Other mood [affective] disorders	0.705	0.295
F34 Persistent mood [affective] disorders	0.705	0.295
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.704	0.296
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.703	0.296
O40 Polyhydramnios	0.703	0.297
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.702	0.298
X50-X57 Overexertion, travel and privation	0.701	0.298
S50.8 Other superficial injuries of forearm	0.701	0.299
M25.78 Osteophyte (Other)	0.701	0.299
F60.9 Personality disorder, unspecified	0.701	0.299
F31.8 Other bipolar affective disorders	0.700	0.300
F31.7 Bipolar affective disorder, currently in remission	0.700	0.300
F31.6 Bipolar affective disorder, current episode mixed	0.700	0.300
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.700	0.300
M33.1 Other dermatomyositis	0.700	0.300
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.699	0.300
S26 Injury of heart	0.699	0.300
S25 Injury of blood vessels of thorax	0.699	0.300
S24 Injury of nerves and spinal cord at thorax level	0.699	0.300
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.699	0.300
S21 Open wound of thorax	0.699	0.300
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.699	0.301
M25.2 Flail joint	0.698	0.302
M25.1 Fistula of joint	0.698	0.302
S80.0 Contusion of knee	0.698	0.302
S00.0 Superficial injury of scalp	0.698	0.302
S01.5 Open wound of lip and oral cavity	0.698	0.302
S86 Injury of muscle and tendon at lower leg level	0.697	0.303
M30 Polyarteritis nodosa and related conditions	0.696	0.304
S22.0 Fracture of thoracic vertebra	0.695	0.305
T15-T19 Effects of foreign body entering through natural orifice	0.694	0.306
S52.10 Fracture of upper end of radius (closed)	0.693	0.307
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.692	0.307
S00.4 Superficial injury of ear	0.692	0.308
S00.2 Other superficial injuries of eyelid and periocular area	0.692	0.308
M47.92 Spondylosis, unspecified (Cervical region)	0.692	0.308
G93.9 Disorder of brain, unspecified	0.690	0.310
M83 Adult osteomalacia	0.690	0.310
M82 Osteoporosis in diseases classified elsewhere	0.690	0.310
M72 Fibroblastic disorders	0.689	0.311
G82 Paraplegia and tetraplegia	0.686	0.314
G35 Multiple sclerosis	0.686	0.314
G98 Other disorders of nervous system, not elsewhere classified	0.686	0.314
G92 Toxic encephalopathy	0.686	0.314
S52.0 Fracture of upper end of ulna	0.686	0.314
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.685	0.315
Q80-Q89 Other congenital malformations	0.684	0.316
G83.4 Cauda equina syndrome	0.683	0.317
S06.9 Intracranial injury, unspecified	0.682	0.318
M84.1 Nonunion of fracture [pseudarthrosis]	0.682	0.318
X40-X49 Accidental poisoning by and exposure to noxious substances	0.681	0.319
S06.5 Traumatic subdural haemorrhage	0.681	0.319
T95 Sequelae of burns, corrosions and frostbite	0.679	0.321
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.679	0.321
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.679	0.321
M25.3 Other instability of joint	0.679	0.321
S06.2 Diffuse brain injury	0.678	0.322
O20-O29 Other maternal disorders predominantly related to pregnancy	0.678	0.322
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.678	0.322
M31 Other necrotising vasculopathies	0.677	0.323
M35.0 Sicca syndrome [Sjogren]	0.677	0.323
W75-W84 Other accidental threats to breathing	0.676	0.324
X60-X84 Intentional self-harm	0.675	0.324
B02.9 Zoster without complication	0.675	0.325
B20-B24 Human immunodeficiency virus [HIV] disease	0.675	0.325
S11 Open wound of neck	0.675	0.325
S20 Superficial injury of thorax	0.675	0.325
M49 Spondylopathies in diseases classified elsewhere	0.675	0.325
G64 Other disorders of peripheral nervous system	0.673	0.326
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.673	0.326
G60 Hereditary and idiopathic neuropathy	0.673	0.327
V40-V49 Car occupant injured in transport accident	0.672	0.328
M25.49 Effusion of joint (Site unspecified)	0.672	0.328
M25.48 Effusion of joint (Other)	0.672	0.328
M25.45 Effusion of joint (Pelvic region and thigh)	0.672	0.328
M25.44 Effusion of joint (Hand)	0.672	0.328
M25.42 Effusion of joint (Upper arm)	0.672	0.328
M25.41 Effusion of joint (Shoulder region)	0.672	0.328
M25.40 Effusion of joint (Multiple sites)	0.672	0.328
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.671	0.329
M47.1 Other spondylosis with myelopathy	0.670	0.330
G90.0 Idiopathic peripheral autonomic neuropathy	0.670	0.330
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.670	0.330
V10-V19 Pedal cyclist injured in transport accident	0.669	0.331
M25.79 Osteophyte (Site unspecified)	0.668	0.332
M25.73 Osteophyte (Forearm)	0.668	0.332
M25.72 Osteophyte (Upper arm)	0.668	0.332
M25.70 Osteophyte (Multiple sites)	0.668	0.332
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.668	0.332
M25.8 Other specified joint disorders	0.665	0.334
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.665	0.335
G93.0 Cerebral cysts	0.665	0.335
T51 Toxic effect of alcohol	0.664	0.336
F30 Manic episode	0.663	0.336
M85 Other disorders of bone density and structure	0.663	0.337
S06.0 Concussion	0.662	0.338
S52.2 Fracture of shaft of ulna	0.662	0.338
S51.9 Open wound of forearm, part unspecified	0.662	0.338
M35.2 Behcet's disease	0.661	0.339
S88 Traumatic amputation of lower leg	0.660	0.340
S87 Crushing injury of lower leg	0.660	0.340
S85 Injury of blood vessels at lower leg level	0.660	0.340
S84 Injury of nerves at lower leg level	0.660	0.340
M80.8 Other osteoporosis with pathological fracture	0.659	0.340
M80.5 Idiopathic osteoporosis with pathological fracture	0.659	0.340
M80.4 Drug-induced osteoporosis with pathological fracture	0.659	0.340
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.659	0.340
M80.2 Osteoporosis of disuse with pathological fracture	0.659	0.340
M79 Other soft tissue disorders, not elsewhere classified	0.659	0.341
B25-B34 Other viral diseases	0.659	0.341
M65-M68 Disorders of synovium and tendon	0.658	0.342
M25.75 Osteophyte (Pelvic region and thigh)	0.658	0.342
G30-G32 Other degenerative diseases of the nervous system	0.657	0.343
S29.8 Other specified injuries of thorax	0.656	0.343
S29.7 Multiple injuries of thorax	0.656	0.343
S29.0 Injury of muscle and tendon at thorax level	0.656	0.343
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.656	0.344
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.655	0.345
T92 Sequelae of injuries of upper limb	0.655	0.345
Q50-Q56 Congenital malformations of genital organs	0.654	0.346
M25.51 Pain in joint (Shoulder region)	0.652	0.348
M81 Osteoporosis without pathological fracture	0.652	0.348
M62.8 Other specified disorders of muscle	0.651	0.349
M60 Myositis	0.651	0.349
O32.1 Maternal care for breech presentation	0.650	0.350
S50.7 Multiple superficial injuries of forearm	0.649	0.350
S50.1 Contusion of other and unspecified parts of forearm	0.649	0.350
S52.30 Fracture of shaft of radius (closed)	0.649	0.351
F33 Recurrent depressive disorder	0.649	0.351
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.648	0.352
S06.7 Intracranial injury with prolonged coma	0.648	0.352
S06.4 Epidural haemorrhage	0.648	0.352
S06.1 Traumatic cerebral oedema	0.648	0.352
M47.0 Anterior spinal and vertebral artery compression syndromes	0.647	0.353
M34 Systemic sclerosis	0.647	0.353
S92 Fracture of foot, except ankle	0.647	0.353
T63 Toxic effect of contact with venomous animals	0.646	0.353
O94-O99 Other obstetric conditions, not elsewhere classified	0.645	0.355
M48 Other spondylopathies	0.644	0.356
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.644	0.356
M80.0 Postmenopausal osteoporosis with pathological fracture	0.643	0.357
M45 Ankylosing spondylitis	0.643	0.357
S14 Injury of nerves and spinal cord at neck level	0.642	0.358
T91.2 Sequelae of other fracture of thorax and pelvis	0.641	0.359
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.641	0.359
G96.1 Disorders of meninges, not elsewhere classified	0.641	0.359
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.640	0.360
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.640	0.360
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.640	0.360
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.640	0.360
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.640	0.360
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.640	0.360
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.640	0.360
M25.06 Haemarthrosis (Lower leg)	0.640	0.360
B01 Varicella [chickenpox]	0.640	0.360
W00-W19 Falls	0.639	0.361
S22.3 Fracture of rib	0.637	0.362
X58-X59 Accidental exposure to other and unspecified factors	0.637	0.363
B50-B64 Protozoal diseases	0.636	0.363
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.635	0.365
M22 Disorders of patella	0.635	0.365
O44.1 Placenta praevia with haemorrhage	0.634	0.366
B90-B94 Sequelae of infectious and parasitic diseases	0.634	0.366
S00.8 Superficial injury of other parts of head	0.634	0.366
X20-X29 Contact with venomous animals and plants	0.633	0.367
M86-M90 Other osteopathies	0.632	0.367
Y35-Y36 Legal intervention and operations of war	0.632	0.368
Y10-Y34 Event of undetermined intent	0.632	0.368
X85-X99 Assault	0.632	0.368
X30-X39 Exposure to forces of nature	0.632	0.368
X10-X19 Contact with heat and hot substances	0.632	0.368
X00-X09 Exposure to smoke, fire and flames	0.632	0.368
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.632	0.368
W65-W74 Accidental drowning and submersion	0.632	0.368
V98-V99 Other and unspecified transport accidents	0.632	0.368
V95-V97 Air and space transport accidents	0.632	0.368
V90-V94 Water transport accidents	0.632	0.368
V70-V79 Bus occupant injured in transport accident	0.632	0.368
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.632	0.368
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.632	0.368
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.632	0.368
V01-V09 Pedestrian injured in transport accident	0.632	0.368
S12 Fracture of neck	0.631	0.369
M91-M94 Chondropathies	0.631	0.369
B35-B49 Mycoses	0.631	0.369
T91.9 Sequelae of unspecified injury of neck and trunk	0.631	0.369
G95.8 Other specified diseases of spinal cord	0.629	0.371
A50-A64 Infections with a predominantly sexual mode of transmission	0.629	0.371
S22.2 Fracture of sternum	0.629	0.371
S51.7 Multiple open wounds of forearm	0.628	0.372
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.626	0.374
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.626	0.374
M47.94 Spondylosis, unspecified (Thoracic region)	0.626	0.374
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.626	0.374
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.626	0.374
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.626	0.374
S05.8 Other injuries of eye and orbit	0.625	0.375
S22.5 Flail chest	0.625	0.375
S80.7 Multiple superficial injuries of lower leg	0.624	0.376
G83.1 Monoplegia of lower limb	0.624	0.376
T59 Toxic effect of other gases, fumes and vapours	0.623	0.377
M25.53 Pain in joint (Forearm)	0.623	0.377
S59.9 Unspecified injury of forearm	0.623	0.377
S22.40 Multiple fractures of ribs (closed)	0.622	0.378
T91.8 Sequelae of other specified injuries of neck and trunk	0.621	0.378
Y00-Y09 Assault	0.621	0.379
B85-B89 Pediculosis, acariasis and other infestations	0.620	0.380
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.620	0.380
A75-A79 Rickettsioses	0.620	0.380
A70-A74 Other diseases caused by chlamydiae	0.620	0.380
A65-A69 Other spirochaetal diseases	0.620	0.380
A20-A28 Certain zoonotic bacterial diseases	0.620	0.380
A15-A19 Tuberculosis	0.620	0.380
M20 Acquired deformities of fingers and toes	0.619	0.381
G93.4 Encephalopathy, unspecified	0.617	0.382
F68 Other disorders of adult personality and behaviour	0.617	0.383
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.617	0.383
F65 Disorders of sexual preference	0.617	0.383
F64 Gender identity disorders	0.617	0.383
F63 Habit and impulse disorders	0.617	0.383
F62 Enduring personality changes, not attributable to brain damage and disease	0.617	0.383
F69 Unspecified disorder of adult personality and behaviour	0.617	0.383
F61 Mixed and other personality disorders	0.617	0.383
M21.6 Other acquired deformities of ankle and foot	0.617	0.383
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.617	0.383
S22.9 Fracture of bony thorax, part unspecified	0.616	0.384
S22.8 Fracture of other parts of bony thorax	0.616	0.384
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.615	0.384
T91.4 Sequelae of injury of intrathoracic organs	0.615	0.384
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.615	0.384
B15-B19 Viral hepatitis	0.615	0.385
T90.9 Sequelae of unspecified injury of head	0.614	0.386
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.614	0.386
G95.9 Disease of spinal cord, unspecified	0.614	0.386
G90.3 Multisystem degeneration	0.613	0.387
M63 Disorders of muscle in diseases classified elsewhere	0.613	0.387
M61 Calcification and ossification of muscle	0.613	0.387
O32.4 Maternal care for high head at term	0.613	0.387
S52.9 Fracture of forearm, part unspecified	0.613	0.387
S52.7 Multiple fractures of forearm	0.613	0.387
S52.4 Fracture of shafts of both ulna and radius	0.613	0.387
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.612	0.387
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.612	0.388
G80 Infantile cerebral palsy	0.612	0.388
S81.9 Open wound of lower leg, part unspecified	0.612	0.388
S70 Superficial injury of hip and thigh	0.611	0.389
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.611	0.389
S31 Open wound of abdomen, lower back and pelvis	0.611	0.389
S01.2 Open wound of nose	0.611	0.389
G61.9 Inflammatory polyneuropathy, unspecified	0.610	0.390
G62.2 Polyneuropathy due to other toxic agents	0.610	0.390
G62.1 Alcoholic polyneuropathy	0.610	0.390
G62.0 Drug-induced polyneuropathy	0.610	0.390
M25.58 Pain in joint (Other)	0.609	0.390
M84.06 Malunion of fracture (Lower leg)	0.609	0.391
H65-H75 Diseases of middle ear and mastoid	0.609	0.391
G01 Meningitis in bacterial diseases classified elsewhere	0.607	0.392
A80-A89 Viral infections of the central nervous system	0.607	0.393
O85-O92 Complications predominantly related to the puerperium	0.607	0.393
G83.8 Other specified paralytic syndromes	0.606	0.394
M25.52 Pain in joint (Upper arm)	0.606	0.394
S06.30 Focal brain injury (without open intracranial wound)	0.606	0.394
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.606	0.394
V80-V89 Other land transport accidents	0.606	0.394
M35.1 Other overlap syndromes	0.605	0.395
S06.8 Other intracranial injuries	0.604	0.396
O46 Antepartum haemorrhage, not elsewhere classified	0.604	0.396
G95.1 Vascular myelopathies	0.602	0.397
G95.0 Syringomyelia and syringobulbia	0.602	0.397
M84.9 Disorder of continuity of bone, unspecified	0.601	0.398
M84.8 Other disorders of continuity of bone	0.601	0.398
M84.4 Pathological fracture, not elsewhere classified	0.601	0.398
M84.3 Stress fracture, not elsewhere classified	0.601	0.398
M84.2 Delayed union of fracture	0.601	0.398
T98.2 Sequelae of certain early complications of trauma	0.601	0.399
T98.1 Sequelae of other and unspecified effects of external causes	0.601	0.399
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.601	0.399
Y44 Agents primarily affecting blood constituents	0.601	0.399
G40-G47 Episodic and paroxysmal disorders	0.601	0.399
G94.2 Hydrocephalus in other diseases classified elsewhere	0.599	0.400
W29 Contact with other powered hand tools and household machinery	0.599	0.401
G91.1 Obstructive hydrocephalus	0.598	0.402
V20-V29 Motorcycle rider injured in transport accident	0.598	0.402
T65 Toxic effect of other and unspecified substances	0.597	0.402
T62 Toxic effect of other noxious substances eaten as food	0.597	0.402
T61 Toxic effect of noxious substances eaten as seafood	0.597	0.402
T60 Toxic effect of pesticides	0.597	0.402
T57 Toxic effect of other inorganic substances	0.597	0.402
T56 Toxic effect of metals	0.597	0.402
T54 Toxic effect of corrosive substances	0.597	0.402
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.597	0.402
T52 Toxic effect of organic solvents	0.597	0.402
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.597	0.402
T58 Toxic effect of carbon monoxide	0.597	0.402
T55 Toxic effect of soaps and detergents	0.597	0.402
T79.3 Post-traumatic wound infection, not elsewhere classified	0.597	0.403
O45 Premature separation of placenta [abruptio placentae]	0.596	0.404
O33 Maternal care for known or suspected disproportion	0.596	0.404
O31 Complications specific to multiple gestation	0.596	0.404
S22.1 Multiple fractures of thoracic spine	0.593	0.407
W25 Contact with sharp glass	0.593	0.407
W44 Foreign body entering into or through eye or natural orifice	0.592	0.407
T21 Burn and corrosion of trunk	0.592	0.408
W20 Struck by thrown, projected or falling object	0.592	0.408
G96.0 Cerebrospinal fluid leak	0.592	0.408
Y52 Agents primarily affecting the cardiovascular system	0.590	0.409
S17 Crushing injury of neck	0.590	0.410
S15 Injury of blood vessels at neck level	0.590	0.410
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.590	0.410
S18 Traumatic amputation at neck level	0.590	0.410
S16 Injury of muscle and tendon at neck level	0.590	0.410
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.590	0.410

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations