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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12213810
log Bayes Factor = 14.2401
Chromosome 6   position 89,307,322  (GRCh37) Explore rs12213810 on Ensembl!
Variant rs12213810 is part of Cluster X0073

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
S00-S09 Injuries to the head
0.998 0.002 0.000
S01 Open wound of head
0.994 0.006 0.000
I21 Acute myocardial infarction
0.994 0.006 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.991 0.009 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.991 0.009 0.000
Chapter X Diseases of the respiratory system
0.988 0.012 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.986 0.014 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.986 0.014 0.000
M50-M54 Other dorsopathies
0.984 0.016 0.000
Chapter I Certain infectious and parasitic diseases
0.984 0.016 0.000
I21.9 Acute myocardial infarction, unspecified
0.981 0.019 0.000
B95-B98 Bacterial, viral and other infectious agents
0.975 0.025 0.000
I30-I52 Other forms of heart disease
0.974 0.026 0.000
S01.8 Open wound of other parts of head
0.970 0.030 0.000
M54 Dorsalgia
0.968 0.032 0.000
R50-R69 General symptoms and signs
0.967 0.033 0.000
Chapter XIV Diseases of the genitourinary system
0.955 0.045 0.000
I84 Haemorrhoids
0.953 0.047 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.950 0.050 0.000
J30-J39 Other diseases of upper respiratory tract
0.947 0.053 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.943 0.057 0.000
R51 Headache
0.939 0.061 0.000
I24 Other acute ischaemic heart diseases
0.937 0.063 0.000
I84.5 External haemorrhoids without complication
0.936 0.064 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.936 0.064 0.000
S01.5 Open wound of lip and oral cavity
0.935 0.065 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.934 0.066 0.000
Chapter XX External causes of morbidity and mortality
0.933 0.067 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.931 0.069 0.000
M54.5 Low back pain
0.930 0.070 0.000
J34 Other disorders of nose and nasal sinuses
0.930 0.070 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.915 0.085 0.000
N17-N19 Renal failure
0.911 0.089 0.000
R53 Malaise and fatigue
0.911 0.089 0.000
I35 Nonrheumatic aortic valve disorders
0.908 0.092 0.000
Chapter V Mental and behavioural disorders
0.902 0.098 0.000
L60-L75 Disorders of skin appendages
0.894 0.106 0.000
N60-N64 Disorders of breast
0.888 0.112 0.000
J34.2 Deviated nasal septum
0.888 0.112 0.000
M54.2 Cervicalgia
0.887 0.113 0.000
M54.56 Low back pain (Lumbar region)
0.882 0.118 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.882 0.118 0.000
S02 Fracture of skull and facial bones
0.882 0.118 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.881 0.119 0.000
M20-M25 Other joint disorders
0.880 0.120 0.000
T86 Failure and rejection of transplanted organs and tissues
0.878 0.122 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.875 0.125 0.000
I60-I69 Cerebrovascular diseases
0.870 0.130 0.000
R63 Symptoms and signs concerning food and fluid intake
0.867 0.133 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.867 0.133 0.000
M50 Cervical disk disorders
0.866 0.134 0.000
N00-N08 Glomerular diseases
0.865 0.135 0.000
N60 Benign mammary dysplasia
0.864 0.136 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.864 0.136 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.864 0.136 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.860 0.140 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.859 0.141 0.000
I24.8 Other forms of acute ischaemic heart disease
0.857 0.143 0.000
I85 Oesophageal varices
0.857 0.143 0.000
I22 Subsequent myocardial infarction
0.855 0.145 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.853 0.147 0.000
J90-J94 Other diseases of pleura
0.852 0.148 0.000
M45-M49 Spondylopathies
0.851 0.149 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.851 0.149 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.847 0.153 0.000
J95-J99 Other diseases of the respiratory system
0.845 0.155 0.000
I20 Angina pectoris
0.844 0.156 0.000
I21.4 Acute subendocardial myocardial infarction
0.844 0.156 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.842 0.158 0.000
J39 Other diseases of upper respiratory tract
0.840 0.160 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.839 0.161 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.838 0.162 0.000
W00-W19 Falls
0.838 0.162 0.000
I51 Complications and ill-defined descriptions of heart disease
0.833 0.167 0.000
I10-I15 Hypertensive diseases
0.833 0.167 0.000
N19 Unspecified renal failure
0.832 0.168 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.831 0.169 0.000
L72.1 Trichilemmal cyst
0.830 0.170 0.000
S01.2 Open wound of nose
0.830 0.170 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.829 0.171 0.000
M54.22 Cervicalgia (Cervical region)
0.828 0.172 0.000
S01.7 Multiple open wounds of head
0.828 0.172 0.000
S00 Superficial injury of head
0.828 0.172 0.000
M54.3 Sciatica
0.828 0.172 0.000
T93 Sequelae of injuries of lower limb
0.827 0.173 0.000
M54.59 Low back pain (Site unspecified)
0.826 0.174 0.000
J20-J22 Other acute lower respiratory infections
0.824 0.176 0.000
R57 Shock, not elsewhere classified
0.824 0.176 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.824 0.176 0.000
I86 Varicose veins of other sites
0.821 0.179 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.819 0.181 0.000
R21 Rash and other nonspecific skin eruption
0.819 0.181 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.818 0.182 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.815 0.185 0.000
R47-R49 Symptoms and signs involving speech and voice
0.814 0.186 0.000
N17 Acute renal failure
0.813 0.187 0.000
M35 Other systemic involvement of connective tissue
0.811 0.189 0.000
I27 Other pulmonary heart diseases
0.810 0.190 0.000
S50-S59 Injuries to the elbow and forearm
0.809 0.191 0.000
R07.3 Other chest pain
0.809 0.191 0.000
R07 Pain in throat and chest
0.806 0.194 0.000
S80-S89 Injuries to the knee and lower leg
0.804 0.196 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.803 0.197 0.000
M51 Other intervertebral disk disorders
0.800 0.200 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.796 0.204 0.000
M50.1 Cervical disk disorder with radiculopathy
0.795 0.205 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.794 0.206 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.791 0.208 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.791 0.209 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.789 0.211 0.000
Chapter XXII Codes for special purposes
0.788 0.212 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.788 0.212 0.000
I84.1 Internal haemorrhoids with other complications
0.787 0.213 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.787 0.213 0.000
I44 Atrioventricular and left bundle-branch block
0.786 0.214 0.000
I20.9 Angina pectoris, unspecified
0.782 0.218 0.000
I38 Endocarditis, valve unspecified
0.782 0.218 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.780 0.220 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.779 0.221 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.778 0.222 0.000
R60 Oedema, not elsewhere classified
0.778 0.222 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.775 0.225 0.000
I33 Acute and subacute endocarditis
0.775 0.225 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.773 0.227 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.773 0.227 0.000
I69 Sequelae of cerebrovascular disease
0.773 0.227 0.000
S60-S69 Injuries to the wrist and hand
0.773 0.227 0.000
B15-B19 Viral hepatitis
0.772 0.228 0.000
R54 Senility
0.772 0.228 0.000
Chapter VIII Diseases of the ear and mastoid process
0.772 0.228 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.771 0.229 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.771 0.229 0.000
F10.1 Harmful use
0.771 0.229 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.771 0.229 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.770 0.229 0.000
R63.0 Anorexia
0.769 0.231 0.000
I50 Heart failure
0.769 0.231 0.000
I35.0 Aortic (valve) stenosis
0.768 0.232 0.000
S01.3 Open wound of ear
0.766 0.234 0.000
J39.2 Other diseases of pharynx
0.766 0.234 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.763 0.237 0.000
A00-A09 Intestinal infectious diseases
0.762 0.238 0.000
I42 Cardiomyopathy
0.761 0.239 0.000
F10.2 Dependence syndrome
0.760 0.240 0.000
R59 Enlarged lymph nodes
0.760 0.240 0.000
Y52 Agents primarily affecting the cardiovascular system
0.758 0.242 0.000
T90 Sequelae of injuries of head
0.758 0.242 0.000
J00-J06 Acute upper respiratory infections
0.758 0.242 0.000
R58 Haemorrhage, not elsewhere classified
0.758 0.242 0.000
M80-M85 Disorders of bone density and structure
0.757 0.242 0.000
S90-S99 Injuries to the ankle and foot
0.756 0.244 0.000
A80-A89 Viral infections of the central nervous system
0.755 0.245 0.000
R20 Disturbances of skin sensation
0.755 0.245 0.000
I84.6 Residual haemorrhoidal skin tags
0.755 0.245 0.000
T98 Sequelae of other and unspecified effects of external causes
0.754 0.246 0.000
M31 Other necrotising vasculopathies
0.752 0.248 0.000
B25-B34 Other viral diseases
0.748 0.252 0.000
T92 Sequelae of injuries of upper limb
0.748 0.252 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.748 0.252 0.000
M23 Internal derangement of knee
0.748 0.252 0.000
I35.8 Other aortic valve disorders
0.747 0.253 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.747 0.253 0.000
S02.2 Fracture of nasal bones
0.746 0.254 0.000
T86.1 Kidney transplant failure and rejection
0.745 0.255 0.000
I31 Other diseases of pericardium
0.745 0.255 0.000
T79-T79 Certain early complications of trauma
0.745 0.255 0.000
S70-S79 Injuries to the hip and thigh
0.745 0.255 0.000
N17.9 Acute renal failure, unspecified
0.743 0.257 0.000
I27.0 Primary pulmonary hypertension
0.743 0.257 0.000
M48 Other spondylopathies
0.743 0.257 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.742 0.258 0.000
Chapter XXI Factors influencing health status and contact with health services
0.742 0.258 0.000
I35.1 Aortic (valve) insufficiency
0.742 0.258 0.000
I35.9 Aortic valve disorder, unspecified
0.742 0.258 0.000
M40-M43 Deforming dorsopathies
0.742 0.258 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.740 0.259 0.000
N25-N29 Other disorders of kidney and ureter
0.739 0.261 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.738 0.262 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.738 0.262 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.737 0.263 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.737 0.263 0.000
M35.3 Polymyalgia rheumatica
0.735 0.265 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.735 0.265 0.000
M91-M94 Chondropathies
0.734 0.266 0.000
W19 Unspecified fall
0.731 0.269 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.731 0.269 0.000
S01.9 Open wound of head, part unspecified
0.730 0.270 0.000
I67 Other cerebrovascular diseases
0.730 0.270 0.000
F99-F99 Unspecified mental disorder
0.729 0.271 0.000
X50-X57 Overexertion, travel and privation
0.727 0.273 0.000
J94 Other pleural conditions
0.724 0.276 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.724 0.276 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.724 0.276 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.723 0.277 0.000
N60.8 Other benign mammary dysplasias
0.723 0.277 0.000
R57.0 Cardiogenic shock
0.722 0.278 0.000
L72.0 Epidermal cyst
0.722 0.278 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.722 0.278 0.000
N60.2 Fibroadenosis of breast
0.722 0.278 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.720 0.280 0.000
V40-V49 Car occupant injured in transport accident
0.720 0.280 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.720 0.280 0.000
S00.8 Superficial injury of other parts of head
0.719 0.281 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.717 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R22.2 Localised swelling, mass and lump, trunk
0.717 0.283 0.000
N02 Recurrent and persistent haematuria
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
S08 Traumatic amputation of part of head
0.716 0.284 0.000
S07 Crushing injury of head
0.716 0.284 0.000
S05 Injury of eye and orbit
0.716 0.284 0.000
S04 Injury of cranial nerves
0.716 0.284 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.716 0.284 0.000
N60.0 Solitary cyst of breast
0.715 0.285 0.000
J60-J70 Lung diseases due to external agents
0.715 0.285 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.713 0.287 0.000
S01.4 Open wound of cheek and temporomandibular area
0.713 0.287 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.713 0.287 0.000
E10-E14 Diabetes mellitus
0.713 0.287 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.712 0.288 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.712 0.288 0.000
M22 Disorders of patella
0.712 0.288 0.000
I51.0 Cardiac septal defect, acquired
0.712 0.288 0.000
M60-M63 Disorders of muscles
0.710 0.290 0.000
M00-M03 Infectious arthropathies
0.710 0.290 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.290 0.000
M70-M79 Other soft tissue disorders
0.710 0.290 0.000
I84.3 External thrombosed haemorrhoids
0.710 0.290 0.000
I85.0 Oesophageal varices with bleeding
0.709 0.291 0.000
I34 Nonrheumatic mitral valve disorders
0.709 0.291 0.000
F10.3 Withdrawal state
0.708 0.292 0.000
I88 Nonspecific lymphadenitis
0.707 0.293 0.000
I87 Other disorders of veins
0.707 0.293 0.000
I71 Aortic aneurysm and dissection
0.707 0.293 0.000
T87 Complications peculiar to reattachment and amputation
0.707 0.293 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.707 0.293 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.706 0.294 0.000
M53 Other dorsopathies, not elsewhere classified
0.706 0.294 0.000
S20-S29 Injuries to the thorax
0.706 0.294 0.000
I77 Other disorders of arteries and arterioles
0.706 0.294 0.000
S02.5 Fracture of tooth
0.705 0.295 0.000
B99-B99 Other infectious diseases
0.705 0.295 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.705 0.295 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.705 0.295 0.000
B65-B83 Helminthiases
0.705 0.295 0.000
B50-B64 Protozoal diseases
0.705 0.295 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.705 0.295 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.705 0.295 0.000
A75-A79 Rickettsioses
0.705 0.295 0.000
A70-A74 Other diseases caused by chlamydiae
0.705 0.295 0.000
A65-A69 Other spirochaetal diseases
0.705 0.295 0.000
A20-A28 Certain zoonotic bacterial diseases
0.705 0.295 0.000
A15-A19 Tuberculosis
0.705 0.295 0.000
I85.9 Oesophageal varices without bleeding
0.704 0.296 0.000
I86.4 Gastric varices
0.702 0.298 0.000
I84.4 External haemorrhoids with other complications
0.702 0.298 0.000
I81 Portal vein thrombosis
0.701 0.299 0.000
J33 Nasal polyp
0.701 0.299 0.000
N75 Diseases of Bartholin's gland
0.700 0.300 0.000
N03 Chronic nephritic syndrome
0.700 0.300 0.000
N61 Inflammatory disorders of breast
0.699 0.301 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.699 0.301 0.000
I52 Other heart disorders in diseases classified elsewhere
0.698 0.302 0.000
I48 Atrial fibrillation and flutter
0.698 0.302 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.698 0.302 0.000
I41 Myocarditis in diseases classified elsewhere
0.698 0.302 0.000
I40 Acute myocarditis
0.698 0.302 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.698 0.302 0.000
I37 Pulmonary valve disorders
0.698 0.302 0.000
I36 Nonrheumatic tricuspid valve disorders
0.698 0.302 0.000
I32 Pericarditis in diseases classified elsewhere
0.698 0.302 0.000
I30 Acute pericarditis
0.698 0.302 0.000
S51 Open wound of forearm
0.698 0.302 0.000
T86.0 Bone-marrow transplant rejection
0.698 0.302 0.000
N60.4 Mammary duct ectasia
0.696 0.304 0.000
I82 Other venous embolism and thrombosis
0.696 0.304 0.000
M54.8 Other dorsalgia
0.694 0.306 0.000
M54.6 Pain in thoracic spine
0.694 0.306 0.000
M54.4 Lumbago with sciatica
0.694 0.306 0.000
M54.0 Panniculitis affecting regions of neck and back
0.694 0.306 0.000
M54.36 Sciatica (Lumbar region)
0.694 0.306 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.694 0.306 0.000
N60.3 Fibrosclerosis of breast
0.693 0.307 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.693 0.307 0.000
R62 Lack of expected normal physiological development
0.693 0.307 0.000
R64 Cachexia
0.693 0.307 0.000
N99-N99 Other disorders of the genitourinary system
0.692 0.308 0.000
I63 Cerebral infarction
0.692 0.308 0.000
N76 Other inflammation of vagina and vulva
0.692 0.308 0.000
R60.9 Oedema, unspecified
0.691 0.309 0.000
Chapter VI Diseases of the nervous system
0.690 0.310 0.000
S06 Intracranial injury
0.690 0.310 0.000
N60.1 Diffuse cystic mastopathy
0.690 0.310 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.689 0.311 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.689 0.311 0.000
S40-S49 Injuries to the shoulder and upper arm
0.689 0.311 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.687 0.313 0.000
W20-W49 Exposure to inanimate mechanical forces
0.686 0.313 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.686 0.314 0.000
R47 Speech disturbances, not elsewhere classified
0.685 0.314 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.685 0.315 0.000
L03 Cellulitis
0.684 0.316 0.000
I84.0 Internal thrombosed haemorrhoids
0.683 0.317 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.683 0.317 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.682 0.318 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.682 0.318 0.000
S00.7 Multiple superficial injuries of head
0.681 0.319 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.681 0.319 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.681 0.319 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.681 0.319 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.681 0.319 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.681 0.319 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.680 0.320 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.680 0.320 0.000
I44.1 Atrioventricular block, second degree
0.679 0.321 0.000
J37 Chronic laryngitis and laryngotracheitis
0.679 0.321 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.678 0.322 0.000
J95.0 Tracheostomy malfunction
0.678 0.322 0.000
L73 Other follicular disorders
0.678 0.322 0.000
T93.2 Sequelae of other fractures of lower limb
0.678 0.322 0.000
T95 Sequelae of burns, corrosions and frostbite
0.676 0.324 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.676 0.324 0.000
T91 Sequelae of injuries of neck and trunk
0.676 0.324 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.676 0.324 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.676 0.324 0.000
R61 Hyperhidrosis
0.675 0.325 0.000
I12 Hypertensive renal disease
0.675 0.325 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.675 0.325 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.674 0.326 0.000
W19.4 Street and highway
0.674 0.326 0.000
I70 Atherosclerosis
0.673 0.327 0.000
I80 Phlebitis and thrombophlebitis
0.673 0.327 0.000
J93 Pneumothorax
0.673 0.327 0.000
I24.1 Dressler's syndrome
0.672 0.328 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.672 0.328 0.000
J92 Pleural plaque
0.671 0.329 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.671 0.329 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.671 0.329 0.000
T88.9 Complication of surgical and medical care, unspecified
0.671 0.329 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.671 0.329 0.000
T88.5 Other complications of anaesthesia
0.671 0.329 0.000
T88.4 Failed or difficult intubation
0.671 0.329 0.000
T88.3 Malignant hyperthermia due to anaesthesis
0.671 0.329 0.000
T88.2 Shock due to anaesthesia
0.671 0.329 0.000
T88.1 Other complications following immunisation, not elsewhere classified
0.671 0.329 0.000
T88.0 Infection following immunisation
0.671 0.329 0.000
S02.6 Fracture of mandible
0.670 0.330 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.669 0.331 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.669 0.331 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.669 0.331 0.000
Y35-Y36 Legal intervention and operations of war
0.669 0.331 0.000
Y10-Y34 Event of undetermined intent
0.669 0.331 0.000
Y00-Y09 Assault
0.669 0.331 0.000
X85-X99 Assault
0.669 0.331 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.669 0.331 0.000
X30-X39 Exposure to forces of nature
0.669 0.331 0.000
X20-X29 Contact with venomous animals and plants
0.669 0.331 0.000
X10-X19 Contact with heat and hot substances
0.669 0.331 0.000
X00-X09 Exposure to smoke, fire and flames
0.669 0.331 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.669 0.331 0.000
W75-W84 Other accidental threats to breathing
0.669 0.331 0.000
W65-W74 Accidental drowning and submersion
0.669 0.331 0.000
W50-W64 Exposure to animate mechanical forces
0.669 0.331 0.000
V98-V99 Other and unspecified transport accidents
0.669 0.331 0.000
V95-V97 Air and space transport accidents
0.669 0.331 0.000
V90-V94 Water transport accidents
0.669 0.331 0.000
V80-V89 Other land transport accidents
0.669 0.331 0.000
V70-V79 Bus occupant injured in transport accident
0.669 0.331 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.669 0.331 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.669 0.331 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.669 0.331 0.000
V20-V29 Motorcycle rider injured in transport accident
0.669 0.331 0.000
V01-V09 Pedestrian injured in transport accident
0.669 0.331 0.000
L10-L14 Bullous disorders
0.667 0.333 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.667 0.333 0.000
M54.55 Low back pain (Thoracolumbar region)
0.667 0.333 0.000
M54.54 Low back pain-Thoracic
0.667 0.333 0.000
M54.53 Low back pain-Cervicothoracic
0.667 0.333 0.000
M54.52 Low back pain-Cervical
0.667 0.333 0.000
M54.51 Low back pain-Occipit-atl-axl
0.667 0.333 0.000
M54.50 Low back pain (Multiple sites in spine)
0.667 0.333 0.000
J20 Acute bronchitis
0.666 0.334 0.000
Y40 Systemic antibiotics
0.666 0.334 0.000
M48.0 Spinal stenosis
0.665 0.335 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.663 0.337 0.000
Y52.1 Calcium-channel blockers
0.663 0.337 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.663 0.337 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.663 0.337 0.000
M24 Other specific joint derangements
0.662 0.338 0.000
M35.0 Sicca syndrome [Sjogren]
0.662 0.338 0.000
M86-M90 Other osteopathies
0.661 0.338 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.662 0.338 0.000
V10-V19 Pedal cyclist injured in transport accident
0.659 0.341 0.000
W10 Fall on and from stairs and steps
0.659 0.341 0.000
S80 Superficial injury of lower leg
0.657 0.343 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.656 0.344 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.656 0.344 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.656 0.344 0.000
J95.8 Other postprocedural respiratory disorders
0.656 0.344 0.000
N70 Salpingitis and oophoritis
0.655 0.345 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.655 0.345 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.655 0.345 0.000
M46 Other inflammatory spondylopathies
0.654 0.346 0.000
Y44 Agents primarily affecting blood constituents
0.654 0.346 0.000
I10 Essential (primary) hypertension
0.654 0.346 0.000
J91 Pleural effusion in conditions classified elsewhere
0.653 0.346 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.653 0.347 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.653 0.347 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.653 0.347 0.000
I61 Intracerebral haemorrhage
0.652 0.347 0.000
J22 Unspecified acute lower respiratory infection
0.651 0.349 0.000
M54.39 Sciatica (Site unspecified)
0.651 0.349 0.000
X60-X84 Intentional self-harm
0.650 0.349 0.000
E10 Insulin-dependent diabetes mellitus
0.650 0.350 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.650 0.350 0.000
S02.20 Fracture of nasal bones (closed)
0.650 0.350 0.000
S01.1 Open wound of eyelid and periocular area
0.649 0.350 0.000
L60 Nail disorders
0.649 0.351 0.000
I50.1 Left ventricular failure
0.649 0.351 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.648 0.352 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.647 0.352 0.000
T20 Burn and corrosion of head and neck
0.647 0.353 0.000
M51.2 Other specified intervertebral disk displacement
0.647 0.353 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.647 0.353 0.000
F80-F89 Disorders of psychological development
0.647 0.353 0.000
F70-F79 Mental retardation
0.647 0.353 0.000
F60-F69 Disorders of adult personality and behaviour
0.647 0.353 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.647 0.353 0.000
N05 Unspecified nephritic syndrome
0.646 0.354 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.646 0.354 0.000
R22.1 Localised swelling, mass and lump, neck
0.646 0.354 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.646 0.354 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.645 0.355 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.645 0.355 0.000
T39.1 4-Aminophenol derivatives
0.645 0.355 0.000
G90-G99 Other disorders of the nervous system
0.645 0.355 0.000
M23.8 Other internal derangements of knee
0.644 0.356 0.000
M31.6 Other giant cell arteritis
0.643 0.357 0.000
J35 Chronic diseases of tonsils and adenoids
0.641 0.359 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.641 0.359 0.000
N62 Hypertrophy of breast
0.641 0.359 0.000
L75 Apocrine sweat disorders
0.641 0.359 0.000
L74 Eccrine sweat disorders
0.641 0.359 0.000
L70 Acne
0.641 0.359 0.000
L68 Hypertrichosis
0.641 0.359 0.000
L67 Hair colour and hair shaft abnormalities
0.641 0.359 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.641 0.359 0.000
L65 Other nonscarring hair loss
0.641 0.359 0.000
L64 Androgenic alopecia
0.641 0.359 0.000
L63 Alopecia areata
0.641 0.359 0.000
L62 Nail disorders in diseases classified elsewhere
0.641 0.359 0.000
Z30 Contraceptive management
0.641 0.359 0.000
R59.0 Localised enlarged lymph nodes
0.640 0.360 0.000
M50.3 Other cervical disk degeneration
0.640 0.360 0.000
I44.0 Atrioventricular block, first degree
0.639 0.361 0.000
N18 Chronic renal failure
0.639 0.361 0.000
R00 Abnormalities of heart beat
0.639 0.361 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.638 0.362 0.000
T66-T78 Other and unspecified effects of external causes
0.638 0.362 0.000
M21 Other acquired deformities of limbs
0.638 0.362 0.000
S09 Other and unspecified injuries of head
0.637 0.363 0.000
W08 Fall involving other furniture
0.636 0.364 0.000
I69.3 Sequelae of cerebral infarction
0.636 0.364 0.000
I27.2 Other secondary pulmonary hypertension
0.636 0.364 0.000
M54.29 Cervicalgia-Site unspe
0.636 0.364 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.636 0.364 0.000
M54.27 Cervicalgia-Lumbosacral
0.636 0.364 0.000
M54.26 Cervicalgia-Lumbar
0.636 0.364 0.000
M54.25 Cervicalgia-Thoracolumbar
0.636 0.364 0.000
M54.24 Cervicalgia-Thoracic
0.636 0.364 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.636 0.364 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.636 0.364 0.000
M54.20 Cervicalgia-Mult site
0.636 0.364 0.000
T31 Burns classified according to extent of body surface involved
0.634 0.365 0.000
M54.1 Radiculopathy
0.634 0.365 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.634 0.366 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.633 0.367 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.633 0.367 0.000
L71 Rosacea
0.632 0.367 0.000
I28 Other diseases of pulmonary vessels
0.632 0.367 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.632 0.368 0.000
S02.8 Fractures of other skull and facial bones
0.632 0.368 0.000
S02.7 Multiple fractures involving skull and facial bones
0.632 0.368 0.000
S02.3 Fracture of orbital floor
0.632 0.368 0.000
S02.1 Fracture of base of skull
0.632 0.368 0.000
S02.0 Fracture of vault of skull
0.632 0.368 0.000
R63.4 Abnormal weight loss
0.632 0.368 0.000
I33.0 Acute and subacute infective endocarditis
0.632 0.368 0.000
I47 Paroxysmal tachycardia
0.632 0.368 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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