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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12214804
log Bayes Factor = 1.50806
Chromosome 6   position 34,188,866  (GRCh37) Explore rs12214804 on Ensembl!
Variant rs12214804 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
0.000 0.058 0.942
I34 Nonrheumatic mitral valve disorders
0.000 0.060 0.940
I34.0 Mitral (valve) insufficiency
0.000 0.065 0.935
Chapter IX Diseases of the circulatory system
0.000 0.080 0.920
I45 Other conduction disorders
0.000 0.083 0.917
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.098 0.902
I10-I15 Hypertensive diseases
0.000 0.103 0.897
I20-I25 Ischaemic heart diseases
0.000 0.108 0.892
I10 Essential (primary) hypertension
0.000 0.113 0.887
I49 Other cardiac arrhythmias
0.000 0.116 0.884
I25 Chronic ischaemic heart disease
0.000 0.146 0.854
I77 Other disorders of arteries and arterioles
0.000 0.150 0.850
I34.1 Mitral (valve) prolapse
0.000 0.162 0.838
I25.1 Atherosclerotic heart disease
0.000 0.162 0.838
I71 Aortic aneurysm and dissection
0.000 0.163 0.837
I50 Heart failure
0.000 0.166 0.834
I49.5 Sick sinus syndrome
0.000 0.171 0.829
I77.6 Arteritis, unspecified
0.000 0.176 0.824
I50.0 Congestive heart failure
0.000 0.195 0.805
I35 Nonrheumatic aortic valve disorders
0.000 0.203 0.797
I45.6 Preexcitation syndrome
0.000 0.204 0.796
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.209 0.791
I25.2 Old myocardial infarction
0.000 0.224 0.776
I45.5 Other specified heart block
0.000 0.227 0.773
I74 Arterial embolism and thrombosis
0.000 0.231 0.769
I51 Complications and ill-defined descriptions of heart disease
0.000 0.233 0.767
I24 Other acute ischaemic heart diseases
0.000 0.234 0.766
I49.9 Cardiac arrhythmia, unspecified
0.000 0.252 0.748
I30 Acute pericarditis
0.000 0.253 0.747
I35.9 Aortic valve disorder, unspecified
0.000 0.254 0.746
I77.1 Stricture of artery
0.000 0.257 0.743
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.258 0.742
I45.9 Conduction disorder, unspecified
0.000 0.258 0.742
I13 Hypertensive heart and renal disease
0.000 0.261 0.739
I38 Endocarditis, valve unspecified
0.000 0.262 0.738
I49.1 Atrial premature depolarisation
0.000 0.263 0.736
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.272 0.728
I24.8 Other forms of acute ischaemic heart disease
0.000 0.278 0.722
I47 Paroxysmal tachycardia
0.000 0.279 0.721
I45.4 Nonspecific intraventricular block
0.000 0.281 0.719
I45.1 Other and unspecified right bundle-branch block
0.000 0.283 0.716
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.288 0.712
I72 Other aneurysm
0.000 0.291 0.709
I05-I09 Chronic rheumatic heart diseases
0.000 0.296 0.704
I45.2 Bifascicular block
0.000 0.296 0.704
I45.3 Trifascicular block
0.000 0.300 0.700
I11 Hypertensive heart disease
0.000 0.301 0.699
I49.8 Other specified cardiac arrhythmias
0.000 0.304 0.696
I45.0 Right fascicular block
0.000 0.308 0.692
I36 Nonrheumatic tricuspid valve disorders
0.000 0.311 0.689
I70 Atherosclerosis
0.000 0.312 0.688
I52 Other heart disorders in diseases classified elsewhere
0.000 0.324 0.676
I48 Atrial fibrillation and flutter
0.000 0.324 0.676
I41 Myocarditis in diseases classified elsewhere
0.000 0.324 0.676
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.324 0.676
I32 Pericarditis in diseases classified elsewhere
0.000 0.324 0.676
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.325 0.675
I21 Acute myocardial infarction
0.000 0.334 0.666
I74.8 Embolism and thrombosis of other arteries
0.000 0.341 0.659
I77.2 Rupture of artery
0.000 0.351 0.649
I49.0 Ventricular fibrillation and flutter
0.000 0.355 0.645
I40 Acute myocarditis
0.000 0.356 0.644
I22 Subsequent myocardial infarction
0.000 0.357 0.643
I37 Pulmonary valve disorders
0.000 0.357 0.643
I21.9 Acute myocardial infarction, unspecified
0.000 0.359 0.641
I00-I02 Acute rheumatic fever
0.000 0.362 0.638
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.363 0.637
I71.0 Dissection of aorta [any part]
0.000 0.364 0.636
I51.8 Other ill-defined heart diseases
0.000 0.364 0.636
I49.2 Junctional premature depolarisation
0.000 0.366 0.634
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.371 0.629
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.375 0.625
I45.8 Other specified conduction disorders
0.000 0.380 0.620
I72.3 Aneurysm of iliac artery
0.000 0.384 0.616
I23 Certain current complications following acute myocardial infarction
0.000 0.385 0.615
I25.6 Silent myocardial ischaemia
0.000 0.385 0.615
I35.1 Aortic (valve) insufficiency
0.000 0.389 0.611
I20 Angina pectoris
0.000 0.389 0.611
I77.5 Necrosis of artery
0.000 0.390 0.609
I77.4 Coeliac artery compression syndrome
0.000 0.390 0.609
I30.9 Acute pericarditis, unspecified
0.000 0.395 0.604
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.400 0.600
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.400 0.600
I25.5 Ischaemic cardiomyopathy
0.000 0.400 0.600
I51.9 Heart disease, unspecified
0.000 0.405 0.595
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.406 0.594
I77.0 Arteriovenous fistula, acquired
0.000 0.409 0.591
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.409 0.591
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.414 0.586
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.415 0.585
I83 Varicose veins of lower extremities
0.000 0.416 0.584
I78 Diseases of capillaries
0.000 0.416 0.584
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.418 0.582
I51.6 Cardiovascular disease, unspecified
0.000 0.418 0.582
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.419 0.581
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.424 0.576
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.424 0.575
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.426 0.574
I47.1 Supraventricular tachycardia
0.000 0.430 0.570
I51.5 Myocardial degeneration
0.000 0.431 0.569
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.432 0.568
I77.3 Arterial fibromuscular dysplasia
0.000 0.435 0.565
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.435 0.565
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.436 0.564
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.438 0.561
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.440 0.560
I74.5 Embolism and thrombosis of iliac artery
0.000 0.440 0.560
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.441 0.559
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.444 0.556
I15 Secondary hypertension
0.000 0.445 0.555
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.450 0.550
I33 Acute and subacute endocarditis
0.000 0.454 0.546
I30.1 Infective pericarditis
0.000 0.455 0.545
I05 Rheumatic mitral valve diseases
0.000 0.455 0.545
I20.0 Unstable angina
0.000 0.456 0.544
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.459 0.541
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.461 0.539
I06 Rheumatic aortic valve diseases
0.000 0.462 0.538
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.464 0.535
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.465 0.535
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.466 0.534
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.467 0.533
I72.8 Aneurysm of other specified arteries
0.000 0.468 0.532
I24.1 Dressler's syndrome
0.000 0.468 0.532
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.470 0.530
I77.8 Other specified disorders of arteries and arterioles
0.000 0.470 0.529
I47.0 Reentry ventricular arrhythmia
0.000 0.471 0.529
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.472 0.528
I30.8 Other forms of acute pericarditis
0.000 0.472 0.528
I44 Atrioventricular and left bundle-branch block
0.000 0.473 0.527
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.474 0.526
I70.0 Atherosclerosis of aorta
0.000 0.477 0.523
I72.1 Aneurysm of artery of upper extremity
0.000 0.477 0.523
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.481 0.519
I42 Cardiomyopathy
0.000 0.485 0.515
I70.1 Atherosclerosis of renal artery
0.000 0.488 0.512
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.489 0.511
I07 Rheumatic tricuspid valve diseases
0.000 0.491 0.509
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.491 0.509
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.492 0.508
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.492 0.507
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.493 0.507
I49.4 Other and unspecified premature depolarisation
0.000 0.493 0.507
I09 Other rheumatic heart diseases
0.000 0.497 0.503
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.501 0.499
I20.1 Angina pectoris with documented spasm
0.000 0.503 0.497
I35.0 Aortic (valve) stenosis
0.000 0.504 0.496
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.505 0.495
I72.4 Aneurysm of artery of lower extremity
0.000 0.506 0.494
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.506 0.494
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.506 0.494
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.506 0.494
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.506 0.494
I72.0 Aneurysm of carotid artery
0.000 0.514 0.486
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.515 0.484
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.515 0.484
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.515 0.484
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.515 0.484
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.515 0.484
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.515 0.484
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.515 0.484
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.515 0.484
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.515 0.484
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.515 0.484
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.515 0.484
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.515 0.484
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.515 0.484
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.515 0.484
I48.4 Atypical atrial flutter
0.000 0.515 0.484
I48.3 Typical atrial flutter
0.000 0.515 0.484
I48.2 Chronic atrial fibrillation
0.000 0.515 0.484
I48.1 Persistent atrial fibrillation
0.000 0.515 0.484
I48.0 Paroxysmal atrial fibrillation
0.000 0.515 0.484
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.515 0.484
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.515 0.484
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.515 0.484
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.516 0.484
I73 Other peripheral vascular diseases
0.000 0.518 0.482
I44.7 Left bundle-branch block, unspecified
0.000 0.521 0.479
I72.2 Aneurysm of renal artery
0.000 0.521 0.479
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.521 0.479
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.522 0.478
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.524 0.476
I70.9 Generalised and unspecified atherosclerosis
0.000 0.525 0.475
I37.0 Pulmonary valve stenosis
0.000 0.525 0.475
I40.9 Acute myocarditis, unspecified
0.000 0.526 0.474
I88 Nonspecific lymphadenitis
0.000 0.526 0.474
I08 Multiple valve diseases
0.000 0.529 0.471
I47.2 Ventricular tachycardia
0.000 0.530 0.470
I25.4 Coronary artery aneurysm
0.000 0.530 0.469
I70.8 Atherosclerosis of other arteries
0.000 0.532 0.468
I72.9 Aneurysm of unspecified site
0.000 0.532 0.467
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.538 0.462
I50.1 Left ventricular failure
0.000 0.538 0.462
I51.4 Myocarditis, unspecified
0.000 0.538 0.462
I40.8 Other acute myocarditis
0.000 0.538 0.462
I40.1 Isolated myocarditis
0.000 0.538 0.462
I37.9 Pulmonary valve disorder, unspecified
0.000 0.539 0.461
I37.8 Other pulmonary valve disorders
0.000 0.539 0.461
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.539 0.461
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.540 0.460
I02 Rheumatic chorea
0.000 0.542 0.458
I01 Rheumatic fever with heart involvement
0.000 0.542 0.458
I05.9 Mitral valve disease, unspecified
0.000 0.547 0.453
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.559 0.441
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.559 0.441
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.559 0.441
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.559 0.441
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.559 0.441
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.559 0.441
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.560 0.440
I23.8 Other current complications following acute myocardial infarction
0.000 0.561 0.438
I81 Portal vein thrombosis
0.000 0.561 0.439
I31 Other diseases of pericardium
0.000 0.563 0.437
I00 Rheumatic fever without mention of heart involvement
0.000 0.563 0.437
I15.8 Other secondary hypertension
0.000 0.564 0.436
I50.9 Heart failure, unspecified
0.000 0.565 0.435
I87 Other disorders of veins
0.000 0.572 0.428
I05.8 Other mitral valve diseases
0.000 0.573 0.427
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.577 0.423
I22.8 Subsequent myocardial infarction of other sites
0.000 0.579 0.420
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.580 0.420
I06.0 Rheumatic aortic stenosis
0.000 0.582 0.418
I51.7 Cardiomegaly
0.000 0.583 0.417
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.585 0.415
I40.0 Infective myocarditis
0.000 0.585 0.414
I86 Varicose veins of other sites
0.000 0.587 0.412
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.589 0.411
I78.8 Other diseases of capillaries
0.000 0.589 0.411
I37.1 Pulmonary valve insufficiency
0.000 0.590 0.410
I42.6 Alcoholic cardiomyopathy
0.000 0.591 0.409
I78.9 Disease of capillaries, unspecified
0.000 0.591 0.409
I08.0 Disorders of both mitral and aortic valves
0.000 0.591 0.409
I51.0 Cardiac septal defect, acquired
0.000 0.594 0.406
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.595 0.405
I44.4 Left anterior fascicular block
0.000 0.595 0.404
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.598 0.402
I05.0 Mitral stenosis
0.000 0.599 0.401
I44.1 Atrioventricular block, second degree
0.000 0.602 0.398
I15.9 Seconday hypertension, unspecified
0.000 0.602 0.398
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.603 0.397
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.607 0.392
I15.2 Hypertension secondary to endocrine disorders
0.000 0.611 0.389
I79.1 Aortitis in diseases classified elsewhere
0.000 0.612 0.388
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.612 0.388
I15.0 Renovascular hypertension
0.000 0.613 0.387
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.614 0.386
I06.8 Other rheumatic aortic valve diseases
0.000 0.614 0.386
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.616 0.383
I06.1 Rheumatic aortic insufficiency
0.000 0.619 0.381
I44.5 Left posterior fascicular block
0.000 0.622 0.378
I21.4 Acute subendocardial myocardial infarction
0.000 0.623 0.377
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.624 0.375
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.625 0.375
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.625 0.375
I42.4 Endocardial fibroelastosis
0.000 0.627 0.373
I78.1 Naevus, nonneoplastic
0.000 0.627 0.373
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.630 0.370
I07.1 Tricuspid insufficiency
0.000 0.631 0.369
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.631 0.369
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.631 0.369
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.633 0.367
I05.2 Mitral stenosis with insufficiency
0.000 0.634 0.366
I07.9 Tricuspid valve disease, unspecified
0.000 0.635 0.365
I07.8 Other tricuspid valve diseases
0.000 0.635 0.365
I07.2 Tricuspid stenosis with insufficiency
0.000 0.635 0.365
I07.0 Tricuspid stenosis
0.000 0.635 0.365
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.639 0.361
I09.8 Other specified rheumatic heart diseases
0.000 0.639 0.361
I09.2 Chronic rheumatic pericarditis
0.000 0.639 0.361
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.639 0.361
I09.0 Rheumatic myocarditis
0.000 0.639 0.361
I42.5 Other restrictive cardiomyopathy
0.000 0.639 0.361
I44.2 Atrioventricular block, complete
0.000 0.640 0.360
I09.9 Rheumatic heart disease, unspecified
0.000 0.641 0.359
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.641 0.359
I33.9 Acute endocarditis, unspecified
0.000 0.645 0.354
I49.3 Ventricular premature depolarisation
0.000 0.646 0.354
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.648 0.352
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.649 0.350
I85 Oesophageal varices
0.000 0.650 0.350
I35.8 Other aortic valve disorders
0.001 0.650 0.350
I42.8 Other cardiomyopathies
0.000 0.650 0.350
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.651 0.349
I08.9 Multiple valve disease, unspecified
0.000 0.656 0.344
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.659 0.341
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.664 0.335
I42.2 Other hypertrophic cardiomyopathy
0.000 0.666 0.334
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.666 0.334
I08.8 Other multiple valve diseases
0.000 0.668 0.332
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.671 0.328
I01.8 Other acute rheumatic heart disease
0.000 0.671 0.328
I01.2 Acute rheumatic myocarditis
0.000 0.671 0.328
I01.1 Acute rheumatic endocarditis
0.000 0.671 0.328
I01.0 Acute rheumatic pericarditis
0.000 0.671 0.328
I02.9 Rheumatic chorea without heart involvement
0.000 0.671 0.328
I02.0 Rheumatic chorea with heart involvement
0.000 0.671 0.328
I87.8 Other specified disorders of veins
0.000 0.675 0.325
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.677 0.323
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.678 0.322
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.679 0.321
I73.9 Peripheral vascular disease, unspecified
0.000 0.680 0.320
I25.3 Aneurysm of heart
0.001 0.681 0.318
I33.0 Acute and subacute infective endocarditis
0.000 0.683 0.317
I87.0 Postphlebitic syndrome
0.000 0.683 0.317
I05.1 Rheumatic mitral insufficiency
0.000 0.686 0.314
I31.8 Other specified diseases of pericardium
0.000 0.686 0.313
I31.2 Haemopericardium, not elsewhere classified
0.000 0.686 0.313
I31.1 Chronic constrictive pericarditis
0.000 0.687 0.312
I87.9 Disorder of vein, unspecified
0.000 0.689 0.311
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.690 0.310
I77.9 Disorder of arteries and arterioles, unspecified
0.001 0.692 0.307
I88.8 Other nonspecific lymphadenitis
0.000 0.693 0.306
I73.0 Raynaud's syndrome
0.000 0.696 0.304
I20.8 Other forms of angina pectoris
0.000 0.699 0.301
I86.8 Varicose veins of other specified sites
0.000 0.699 0.301
I86.1 Scrotal varices
0.000 0.700 0.300
I87.1 Compression of vein
0.000 0.702 0.298
I89.1 Lymphangitis
0.000 0.703 0.297
I42.9 Cardiomyopathy, unspecified
0.000 0.704 0.296
I86.2 Pelvic varices
0.000 0.704 0.296
I86.0 Sublingual varices
0.000 0.704 0.296
I44.0 Atrioventricular block, first degree
0.000 0.711 0.289
I86.3 Vulval varices
0.000 0.713 0.287
I86.4 Gastric varices
0.000 0.717 0.283
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.719 0.281
I73.8 Other specified peripheral vascular diseases
0.000 0.720 0.280
I31.0 Chronic adhesive pericarditis
0.000 0.724 0.276
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.727 0.273
I15.1 Hypertension secondary to other renal disorders
0.001 0.727 0.272
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.003 0.729 0.268
I31.3 Pericardial effusion (noninflammatory)
0.000 0.730 0.270
I12 Hypertensive renal disease
0.000 0.730 0.270
I46 Cardiac arrest
0.001 0.730 0.269
E21.0 Primary hyperparathyroidism
0.000 0.733 0.267
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.740 0.260
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.744 0.256
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.744 0.256
I85.9 Oesophageal varices without bleeding
0.000 0.760 0.240
E20-E35 Disorders of other endocrine glands
0.000 0.761 0.239
E21.3 Hyperparathyroidism, unspecified
0.000 0.763 0.237
I82 Other venous embolism and thrombosis
0.000 0.763 0.237
I31.9 Disease of pericardium, unspecified
0.000 0.768 0.232
I42.0 Dilated cardiomyopathy
0.000 0.768 0.232
I44.3 Other and unspecified atrioventricular block
0.001 0.768 0.231
E27 Other disorders of adrenal gland
0.000 0.780 0.220
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.797 0.202
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.798 0.201
E24 Cushing's syndrome
0.000 0.801 0.198
E26 Hyperaldosteronism
0.000 0.803 0.197
E25 Adrenogenital disorders
0.000 0.803 0.197
I85.0 Oesophageal varices with bleeding
0.000 0.804 0.195
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.806 0.194
E21.4 Other specified disorders of parathyroid gland
0.000 0.808 0.192
I46.1 Sudden cardiac death, so described
0.001 0.809 0.190
E28 Ovarian dysfunction
0.000 0.815 0.184
I89.0 Lymphoedema, not elsewhere classified
0.000 0.816 0.184
I28 Other diseases of pulmonary vessels
0.002 0.817 0.181
E21.2 Other hyperparathyroidism
0.000 0.818 0.181
E27.8 Other specified disorders of adrenal gland
0.000 0.823 0.177
E31 Polyglandular dysfunction
0.000 0.824 0.176
I82.0 Budd-Chiari syndrome
0.000 0.825 0.175
E32 Diseases of thymus
0.000 0.825 0.175
N40 Hyperplasia of prostate
0.000 0.827 0.173
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.828 0.171
E30 Disorders of puberty, not elsewhere classified
0.000 0.828 0.171
E27.2 Addisonian crisis
0.000 0.829 0.171
I82.1 Thrombophlebitis migrans
0.000 0.830 0.170
E20 Hypoparathyroidism
0.000 0.830 0.170
E23 Hypofunction and other disorders of pituitary gland
0.000 0.830 0.170
E26.0 Primary hyperaldosteronism
0.000 0.832 0.168
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.833 0.167
I20.9 Angina pectoris, unspecified
0.000 0.833 0.167
E24.9 Cushing's syndrome, unspecified
0.000 0.834 0.166
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.835 0.165
E27.1 Primary adrenocortical insufficiency
0.000 0.836 0.164
E28.3 Primary ovarian failure
0.000 0.836 0.164
E29 Testicular dysfunction
0.000 0.836 0.164
I82.2 Embolism and thrombosis of vena cava
0.000 0.838 0.162
E27.9 Disorder of adrenal gland, unspecified
0.000 0.840 0.160
E27.5 Adrenomedullary hyperfunction
0.000 0.842 0.158
E27.0 Other adrenocortical overactivity
0.000 0.842 0.158
E24.2 Drug-induced Cushing's syndrome
0.000 0.844 0.156
I44.6 Other and unspecified fascicular block
0.002 0.846 0.151
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.850 0.150
E24.8 Other Cushing's syndrome
0.000 0.850 0.150
E22 Hyperfunction of pituitary gland
0.000 0.850 0.149
E34 Other endocrine disorders
0.000 0.851 0.149
I82.3 Embolism and thrombosis of renal vein
0.001 0.852 0.147
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.856 0.144
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.857 0.142
E24.3 Ectopic ACTH syndrome
0.000 0.857 0.142
E24.1 Nelson's syndrome
0.000 0.857 0.142
E26.8 Other hyperaldosteronism
0.000 0.858 0.141
E26.1 Secondary hyperaldosteronism
0.000 0.858 0.141
E25.9 Adrenogenital disorder, unspecified
0.000 0.858 0.141
E25.8 Other adrenogenital disorders
0.000 0.858 0.141
E26.9 Hyperaldosteronism, unspecified
0.000 0.860 0.140
I28.0 Arteriovenous fistula of pulmonary vessels
0.002 0.865 0.133
E28.9 Ovarian dysfunction, unspecified
0.000 0.867 0.132
E28.8 Other ovarian dysfunction
0.000 0.867 0.132
E28.1 Androgen excess
0.000 0.867 0.132
E28.0 Oestrogen excess
0.000 0.867 0.132
I28.1 Aneurysm of pulmonary artery
0.002 0.868 0.130
E31.0 Autoimmune polyglandular failure
0.000 0.869 0.131
I82.9 Embolism and thrombosis of unspecified vein
0.001 0.869 0.130
E32.8 Other diseases of thymus
0.000 0.870 0.130
E23.7 Disorder of pituitary gland, unspecified
0.000 0.871 0.129
E31.9 Polyglandular dysfunction, unspecified
0.000 0.873 0.126
E31.8 Other polyglandular dysfunction
0.000 0.873 0.126
E31.1 Polyglandular hyperfunction
0.000 0.873 0.126
E20.8 Other hypoparathyroidism
0.000 0.874 0.126
E32.1 Abscess of thymus
0.000 0.874 0.125
E32.0 Persistent hyperplasia of thymus
0.000 0.874 0.125
E32.9 Disease of thymus, unspecified
0.000 0.875 0.124
I12.9 Hypertensive renal disease without renal failure
0.001 0.876 0.124
E24.0 Pituitary-dependent Cushing's disease
0.000 0.876 0.124
I28.8 Other specified diseases of pulmonary vessels
0.002 0.876 0.122
I28.9 Disease of pulmonary vessels, unspecified
0.002 0.876 0.122
I82.8 Embolism and thrombosis of other specified veins
0.001 0.877 0.123
E30.9 Disorder of puberty, unspecified
0.000 0.877 0.123
E30.8 Other disorders of puberty
0.000 0.877 0.123
E30.1 Precocious puberty
0.000 0.877 0.123
E30.0 Delayed puberty
0.000 0.877 0.123
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.877 0.123
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.877 0.123
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.877 0.123
E23.0 Hypopituitarism
0.000 0.878 0.122
E20.0 Idiopathic hypoparathyroidism
0.000 0.878 0.122
E23.1 Drug-induced hypopituitarism
0.000 0.878 0.122
I99 Other and unspecified disorders of circulatory system
0.000 0.878 0.122
E20.1 Pseudohypoparathyroidism
0.000 0.879 0.121
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.879 0.121
E29.9 Testicular dysfunction, unspecified
0.000 0.880 0.120
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.880 0.120
I80 Phlebitis and thrombophlebitis
0.000 0.882 0.118
E23.6 Other disorders of pituitary gland
0.000 0.882 0.118
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.882 0.117
E29.8 Other testicular dysfunction
0.000 0.882 0.117
E29.0 Testicular hyperfunction
0.000 0.882 0.117
E20.9 Hypoparathyroidism, unspecified
0.000 0.883 0.117
E23.2 Diabetes insipidus
0.000 0.884 0.116
E34.0 Carcinoid syndrome
0.000 0.885 0.115
E14.9 Without complications
0.000 0.887 0.113
E22.1 Hyperprolactinaemia
0.000 0.889 0.111
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.892 0.108
E14 Unspecified diabetes mellitus
0.000 0.892 0.108
E22.8 Other hyperfunction of pituitary gland
0.000 0.893 0.107
E34.5 Androgen resistance syndrome
0.000 0.893 0.107
E34.4 Constitutional tall stature
0.000 0.893 0.107
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.893 0.107
E34.1 Other hypersecretion of intestinal hormones
0.000 0.893 0.107
E29.1 Testicular hypofunction
0.000 0.893 0.107
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.894 0.106
E10-E14 Diabetes mellitus
0.000 0.895 0.105
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.899 0.101
I26 Pulmonary embolism
0.003 0.899 0.099
E34.3 Short stature, not elsewhere classified
0.000 0.900 0.099
E22.0 Acromegaly and pituitary gigantism
0.000 0.901 0.099
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.902 0.098
E34.9 Endocrine disorder, unspecified
0.000 0.903 0.097
E34.8 Other specified endocrine disorders
0.000 0.904 0.096
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.906 0.094
E10 Insulin-dependent diabetes mellitus
0.000 0.907 0.093
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.909 0.091
I27 Other pulmonary heart diseases
0.004 0.911 0.086
E28.2 Polycystic ovarian syndrome
0.000 0.912 0.088
E14.4 With neurological complications
0.000 0.914 0.086
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.915 0.084
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.915 0.084
I98.0 Cardiovascular syphilis
0.000 0.915 0.084
I46.0 Cardiac arrest with successful resuscitation
0.001 0.917 0.082
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.918 0.082
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.919 0.080
E10.0 With coma
0.000 0.919 0.080
E14.2 Withrenal complications
0.000 0.920 0.080
I46.9 Cardiac arrest, unspecified
0.001 0.920 0.079
E13 Other specified diabetes mellitus
0.000 0.921 0.079
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.921 0.079
E14.5 With peripheral circulatory complications
0.000 0.921 0.079
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.921 0.078
E14.7 With multiple complications
0.000 0.923 0.077
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.923 0.077
E10.4 With neurological complications
0.000 0.924 0.076
E14.0 With coma
0.000 0.924 0.076
I97.0 Postcardiotomy syndrome
0.000 0.924 0.076
E12 Malnutrition-related diabetes mellitus
0.000 0.924 0.076
E83 Disorders of mineral metabolism
0.000 0.925 0.075
E14.1 With ketoacidosis
0.000 0.926 0.074
E14.3 With ophthalmic complications
0.000 0.926 0.074
E10.5 With peripheral circulatory complications
0.000 0.926 0.074
E83.4 Disorders of magnesium metabolism
0.000 0.926 0.074
E70-E90 Metabolic disorders
0.000 0.926 0.074
R00.1 Bradycardia, unspecified
0.000 0.927 0.073
E10.2 With renal complications
0.000 0.927 0.073
N40-N51 Diseases of male genital organs
0.000 0.927 0.073
E10.8 With unspecified complications
0.000 0.927 0.073
E83.1 Disorders of iron metabolism
0.000 0.928 0.072
E14.6 With other specified complications
0.000 0.928 0.072
E10.3 With ophthalmic complications
0.000 0.928 0.072

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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