TreeWAS – Variant ID: rs1230666

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	1.000
E03.9 Hypothyroidism, unspecified	0.000	1.000
E10.9 Without complications	0.000	1.000
E10.1 With ketoacidosis	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	1.000
E10-E14 Diabetes mellitus	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	1.000
E70-E90 Metabolic disorders	0.000	1.000
E11 Non-insulin-dependent diabetes mellitus	0.000	1.000
# Top node	0.000	1.000
E03 Other hypothyroidism	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	1.000
M06 Other rheumatoid arthritis	0.000	1.000
Chapter IX Diseases of the circulatory system	0.000	1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	1.000
E78.0 Pure hypercholesterolaemia	0.001	0.999
Chapter X Diseases of the respiratory system	0.001	0.999
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.001	0.999
E89.0 Postprocedural hypothyroidism	0.001	0.999
I25.1 Atherosclerotic heart disease	0.001	0.999
I21 Acute myocardial infarction	0.001	0.999
M05-M14 Inflammatory polyarthropathies	0.002	0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.002	0.998
E16 Other disorders of pancreatic internal secretion	0.003	0.997
D50-D53 Nutritional anaemias	0.004	0.996
E16.2 Hypoglycaemia, unspecified	0.004	0.996
I25.2 Old myocardial infarction	0.004	0.996
I10-I15 Hypertensive diseases	0.005	0.995
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.005	0.995
D51 Vitamin B12 deficiency anaemia	0.005	0.995
E10.3 With ophthalmic complications	0.006	0.994
I21.9 Acute myocardial infarction, unspecified	0.007	0.993
E11.9 Without complications	0.008	0.992
I10 Essential (primary) hypertension	0.009	0.991
J09-J18 Influenza and pneumonia	0.009	0.991
I22 Subsequent myocardial infarction	0.011	0.989
E11.5 With peripheral circulatory complications	0.013	0.987
D80-D89 Certain disorders involving the immune mechanism	0.020	0.980
I22.9 Subsequent myocardial infarction of unspecified site	0.023	0.977
I25.8 Other forms of chronic ischaemic heart disease	0.024	0.976
E10.5 With peripheral circulatory complications	0.024	0.976
M05 Seropositive rheumatoid arthritis	0.025	0.975
J30-J39 Other diseases of upper respiratory tract	0.031	0.969
J34 Other disorders of nose and nasal sinuses	0.039	0.961
M05.9 Seropositive rheumatoid arthritis, unspecified	0.039	0.961
I25.9 Chronic ischaemic heart disease, unspecified	0.043	0.957
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.049	0.951
J34.8 Other specified disorders of nose and nasal sinuses	0.053	0.947
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.055	0.945
E10.4 With neurological complications	0.059	0.941
M07 Psoriatic and enteropathic arthropathies	0.062	0.938
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.062	0.938
E65-E68 Obesity and other hyperalimentation	0.063	0.937
J20-J22 Other acute lower respiratory infections	0.066	0.934
E10.2 With renal complications	0.071	0.929
M06.3 Rheumatoid nodule	0.074	0.926
I21.2 Acute transmural myocardial infarction of other sites	0.081	0.919
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.081	0.919
E78.8 Other disorders of lipoprotein metabolism	0.082	0.918
E10.8 With unspecified complications	0.085	0.915
J32 Chronic sinusitis	0.092	0.908
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.099	0.901
D60-D64 Aplastic and other anaemias	0.100	0.899
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.102	0.898
J32.9 Chronic sinusitis, unspecified	0.102	0.898
E10.6 With other specified complications	0.103	0.897
J13 Pneumonia due to Streptococcus pneumoniae	0.104	0.896
J15 Bacterial pneumonia, not elsewhere classified	0.108	0.892
D84 Other immunodeficiencies	0.110	0.890
M07.3 Other psoriatic arthropathies	0.111	0.889
M06.0 Seronegative rheumatoid arthritis	0.112	0.888
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.115	0.885
E11.1 With ketoacidosis	0.115	0.885
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.115	0.885
D64 Other anaemias	0.119	0.881
E05 Thyrotoxicosis [hyperthyroidism]	0.120	0.880
E89.3 Postprocedural hypopituitarism	0.120	0.880
I21.0 Acute transmural myocardial infarction of anterior wall	0.124	0.876
D64.9 Anaemia, unspecified	0.125	0.875
M07.39 Other psoriatic arthropathies (Site unspecified)	0.131	0.869
I25.5 Ischaemic cardiomyopathy	0.132	0.868
M06.34 Rheumatoid nodule (Hand)	0.133	0.867
J86 Pyothorax	0.134	0.866
E10.0 With coma	0.135	0.865
D86 Sarcoidosis	0.136	0.864
E66 Obesity	0.137	0.863
E03.8 Other specified hypothyroidism	0.137	0.862
Chapter VI Diseases of the nervous system	0.139	0.861
J80-J84 Other respiratory diseases principally affecting the interstitium	0.140	0.860
I15 Secondary hypertension	0.146	0.854
J20 Acute bronchitis	0.146	0.854
E86 Volume depletion	0.149	0.851
M12 Other specific arthropathies	0.150	0.850
I20 Angina pectoris	0.150	0.850
J34.3 Hypertrophy of nasal turbinates	0.152	0.848
E05.9 Thyrotoxicosis, unspecified	0.154	0.846
G70-G73 Diseases of myoneural junction and muscle	0.156	0.844
J15.9 Bacterial pneumonia, unspecified	0.157	0.843
E66.8 Other obesity	0.159	0.841
D52 Folate deficiency anaemia	0.163	0.837
E06 Thyroiditis	0.164	0.836
I20.9 Angina pectoris, unspecified	0.164	0.836
J33 Nasal polyp	0.165	0.835
M60-M63 Disorders of muscles	0.168	0.832
G70 Myasthenia gravis and other myoneural disorders	0.169	0.831
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.170	0.830
E11.2 With renal complications	0.172	0.828
J86.9 Pyothorax without fistula	0.178	0.822
I22.1 Subsequent myocardial infarction of inferior wall	0.178	0.822
J17 Pneumonia in diseases classified elsewhere	0.180	0.820
J18 Pneumonia, organism unspecified	0.180	0.820
G70.0 Myasthenia gravis	0.185	0.815
I21.4 Acute subendocardial myocardial infarction	0.186	0.814
E78.5 Hyperlipidaemia, unspecified	0.187	0.813
E11.4 With neurological complications	0.187	0.813
E78.1 Pure hyperglyceridaemia	0.190	0.810
M08 Juvenile arthritis	0.192	0.807
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.193	0.807
I13 Hypertensive heart and renal disease	0.196	0.804
M06.8 Other specified rheumatoid arthritis	0.196	0.803
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.197	0.803
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.199	0.801
J12 Viral pneumonia, not elsewhere classified	0.199	0.801
D84.9 Immunodeficiency, unspecified	0.201	0.799
J34.0 Abscess, furuncle and carbuncle of nose	0.201	0.799
E72 Other disorders of amino-acid metabolism	0.206	0.794
D86.3 Sarcoidosis of skin	0.208	0.792
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.208	0.792
I24 Other acute ischaemic heart diseases	0.209	0.791
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.211	0.789
D89.2 Hypergammaglobulinaemia, unspecified	0.214	0.786
M70-M79 Other soft tissue disorders	0.215	0.785
J10 Influenza due to identified influenza virus	0.216	0.784
G00-G09 Inflammatory diseases of the central nervous system	0.217	0.783
H30-H36 Disorders of choroid and retina	0.219	0.781
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.219	0.781
Chapter VII Diseases of the eye and adnexa	0.220	0.780
M75 Shoulder lesions	0.221	0.779
E65 Localised adiposity	0.222	0.778
E89.4 Postprocedural ovarian failure	0.223	0.777
M75.0 Adhesive capsulitis of shoulder	0.224	0.776
E20-E35 Disorders of other endocrine glands	0.225	0.775
E11.0 With coma	0.229	0.771
H36 Retinal disorders in diseases classified elsewhere	0.233	0.767
E11.7 With multiple complications	0.235	0.765
I22.0 Subsequent myocardial infarction of anterior wall	0.237	0.763
E10.7 With multiple complications	0.242	0.758
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.242	0.758
H36.0 Diabetic retinopathy	0.242	0.758
J20.9 Acute bronchitis, unspecified	0.245	0.755
D83 Common variable immunodeficiency	0.246	0.754
D53 Other nutritional anaemias	0.249	0.751
G63 Polyneuropathy in diseases classified elsewhere	0.250	0.750
J21 Acute bronchiolitis	0.251	0.749
M12.2 Villonodular synovitis (pigmented)	0.253	0.747
M75.5 Bursitis of shoulder	0.253	0.747
E11.8 With unspecified complications	0.256	0.744
I25.0 Atherosclerotic cardiovascular disease, so described	0.257	0.743
M05.8 Other seropositive rheumatoid arthritis	0.258	0.742
E16.1 Other hypoglycaemia	0.258	0.741
I21.3 Acute transmural myocardial infarction of unspecified site	0.259	0.741
Chapter XVI Certain conditions originating in the perinatal period	0.262	0.738
E89.5 Postprocedural testicular hypofunction	0.263	0.737
D55-D59 Haemolytic anaemias	0.263	0.737
I24.8 Other forms of acute ischaemic heart disease	0.263	0.737
D84.8 Other specified immunodeficiencies	0.266	0.734
E78.4 Other hyperlipidaemia	0.267	0.733
E06.3 Autoimmune thyroiditis	0.269	0.731
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.269	0.731
J18.9 Pneumonia, unspecified	0.269	0.731
E03.0 Congenital hypothyroidism with diffuse goitre	0.269	0.731
E84 Cystic fibrosis	0.270	0.730
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.271	0.729
H34 Retinal vascular occlusions	0.271	0.729
I70-I79 Diseases of arteries, arterioles and capillaries	0.272	0.728
M06.98 Rheumatoid arthritis, unspecified (Other)	0.272	0.728
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.272	0.728
D89.0 Polyclonal hypergammaglobulinaemia	0.276	0.724
J32.2 Chronic ethmoidal sinusitis	0.277	0.723
J33.9 Nasal polyp, unspecified	0.278	0.722
J34.1 Cyst and mucocele of nose and nasal sinus	0.278	0.722
E02 Subclinical iodine-deficiency hypothyroidism	0.278	0.722
D52.9 Folate deficiency anaemia, unspecified	0.278	0.722
J11 Influenza, virus not identified	0.278	0.722
I15.1 Hypertension secondary to other renal disorders	0.278	0.722
I05-I09 Chronic rheumatic heart diseases	0.279	0.721
G63.2 Diabetic polyneuropathy	0.280	0.720
J33.8 Other polyp of sinus	0.280	0.720
M60 Myositis	0.281	0.719
J90-J94 Other diseases of pleura	0.281	0.719
E78.3 Hyperchylomicronaemia	0.281	0.719
J17.2 Pneumonia in mycoses	0.281	0.719
H55-H59 Other disorders of eye and adnexa	0.282	0.718
M06.1 Adult-onset Still's disease	0.282	0.718
E12 Malnutrition-related diabetes mellitus	0.283	0.717
E76 Disorders of glycosaminoglycan metabolism	0.283	0.717
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.283	0.717
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.283	0.717
E03.5 Myxoedema coma	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.283	0.717
M06.2 Rheumatoid bursitis	0.283	0.717
H35 Other retinal disorders	0.283	0.717
E77 Disorders of glycoprotein metabolism	0.283	0.717
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.284	0.716
I21.X Presumed acute myicardial infaction (unconfirmed)	0.284	0.716
M09 Juvenile arthritis in diseases classified elsewhere	0.284	0.716
E15 Nondiabetic hypoglycaemic coma	0.284	0.715
D86.0 Sarcoidosis of lung	0.285	0.715
E16.9 Disorder of pancreatic internal secretion, unspecified	0.285	0.715
E16.8 Other specified disorders of pancreatic internal secretion	0.285	0.715
E16.4 Abnormal secretion of gastrin	0.285	0.715
E16.3 Increased secretion of glucagon	0.285	0.715
J22 Unspecified acute lower respiratory infection	0.286	0.714
I00-I02 Acute rheumatic fever	0.286	0.714
D51.2 Transcobalamin II deficiency	0.287	0.713
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.287	0.713
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.287	0.713
J20.8 Acute bronchitis due to other specified organisms	0.287	0.712
J84 Other interstitial pulmonary diseases	0.288	0.712
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.289	0.710
Chapter XXII Codes for special purposes	0.290	0.710
M06.33 Rheumatoid nodule (Forearm)	0.290	0.710
M14 Arthropathies in other diseases classified elsewhere	0.292	0.708
M07.6 Other enteropathic arthropathies	0.293	0.707
J80 Adult respiratory distress syndrome	0.294	0.706
J14 Pneumonia due to Haemophilus influenzae	0.296	0.704
M05.1 Rheumatoid lung disease	0.297	0.703
E74 Other disorders of carbohydrate metabolism	0.297	0.702
D81 Combined immunodeficiencies	0.298	0.702
M06.30 Rheumatoid nodule (Multiple sites)	0.298	0.702
J09 Influenza due to certain identified influenza virus	0.299	0.701
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.301	0.699
J15.0 Pneumonia due to Klebsiella pneumoniae	0.302	0.698
M07.30 Other psoriatic arthropathies (Multiple sites)	0.302	0.698
J39 Other diseases of upper respiratory tract	0.303	0.697
J15.8 Other bacterial pneumonia	0.304	0.696
J82 Pulmonary eosinophilia, not elsewhere classified	0.305	0.695
E79 Disorders of purine and pyrimidine metabolism	0.306	0.694
E05.8 Other thyrotoxicosis	0.307	0.693
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.308	0.691
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.309	0.691
E13 Other specified diabetes mellitus	0.310	0.690
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.311	0.689
J18.0 Bronchopneumonia, unspecified	0.312	0.688
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.312	0.687
G20-G26 Extrapyramidal and movement disorders	0.313	0.687
I77 Other disorders of arteries and arterioles	0.313	0.687
H35.3 Degeneration of macula and posterior pole	0.313	0.687
E70 Disorders of aromatic amino-acid metabolism	0.314	0.686
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.315	0.685
E11.3 With ophthalmic complications	0.317	0.683
E03.1 Congenital hypothyroidism without goitre	0.319	0.681
I15.9 Seconday hypertension, unspecified	0.319	0.681
E89.1 Postprocedural hypoinsulinaemia	0.320	0.680
J36 Peritonsillar abscess	0.325	0.675
I23 Certain current complications following acute myocardial infarction	0.325	0.675
E40-E46 Malnutrition	0.327	0.673
G00 Bacterial meningitis, not elsewhere classified	0.327	0.673
M07.5 Arthropathy in ulcerative colitis	0.327	0.673
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.327	0.673
M07.2 Psoriatic spondylitis	0.327	0.673
M07.1 Arthritis mutilans	0.327	0.673
M07.0 Distal interphalangeal psoriatic arthropathy	0.327	0.673
M07.38 Other psoriatic arthropathies (Other)	0.328	0.672
E67 Other hyperalimentation	0.328	0.672
E68 Sequelae of hyperalimentation	0.328	0.672
J92 Pleural plaque	0.328	0.672
J15.2 Pneumonia due to staphylococcus	0.328	0.672
E78.2 Mixed hyperlipidaemia	0.328	0.672
E89.8 Other postprocedural endocrine and metabolic disorders	0.330	0.670
E28 Ovarian dysfunction	0.331	0.669
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.333	0.667
D51.3 Other dietary vitamin B12 deficiency anaemia	0.333	0.666
J12.2 Parainfluenza virus pneumonia	0.334	0.666
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.335	0.664
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.336	0.664
M06.39 Rheumatoid nodule (Site unspecified)	0.336	0.664
M06.38 Rheumatoid nodule (Other)	0.336	0.664
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.336	0.664
M06.31 Rheumatoid nodule (Shoulder region)	0.336	0.664
M76 Enthesopathies of lower limb, excluding foot	0.336	0.663
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.337	0.663
M05.0 Felty's syndrome	0.338	0.661
D80 Immunodeficiency with predominantly antibody defects	0.339	0.661
J32.1 Chronic frontal sinusitis	0.341	0.659
E11.6 With other specified complications	0.341	0.659
J86.0 Pyothorax with fistula	0.341	0.659
G70.8 Other specified myoneural disorders	0.343	0.657
D69 Purpura and other haemorrhagic conditions	0.343	0.657
J15.1 Pneumonia due to Pseudomonas	0.344	0.656
E16.0 Drug-induced hypoglycaemia without coma	0.344	0.656
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.344	0.656
M05.2 Rheumatoid vasculitis	0.344	0.656
M62 Other disorders of muscle	0.345	0.655
I05 Rheumatic mitral valve diseases	0.348	0.652
J10.0 Influenza with pneumonia, influenza virus identified	0.349	0.651
D82 Immunodeficiency associated with other major defects	0.350	0.650
M75.2 Bicipital tendinitis	0.350	0.650
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.350	0.650
M06.37 Rheumatoid nodule (Ankle and foot)	0.350	0.650
J92.9 Pleural plaque without asbestos	0.351	0.649
M06.4 Inflammatory polyarthropathy	0.351	0.649
I25.4 Coronary artery aneurysm	0.351	0.649
I25.6 Silent myocardial ischaemia	0.352	0.648
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.352	0.648
G72 Other myopathies	0.353	0.647
S00-S09 Injuries to the head	0.353	0.647
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.353	0.647
M11 Other crystal arthropathies	0.354	0.646
M06.32 Rheumatoid nodule (Upper arm)	0.355	0.644
S02 Fracture of skull and facial bones	0.356	0.644
H34.2 Other retinal artery occlusions	0.356	0.644
E78.6 Lipoprotein deficiency	0.356	0.644
H46-H48 Disorders of optic nerve and visual pathways	0.357	0.643
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.358	0.642
M60.9 Myositis, unspecified	0.358	0.642
E06.1 Subacute thyroiditis	0.359	0.641
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.359	0.641
M00-M03 Infectious arthropathies	0.359	0.641
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.359	0.641
J15.3 Pneumonia due to streptococcus, group B	0.360	0.640
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.362	0.638
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.362	0.638
D89.1 Cryoglobulinaemia	0.362	0.638
M07.33 Other psoriatic arthropathies (Forearm)	0.363	0.637
M07.32 Other psoriatic arthropathies (Upper arm)	0.363	0.637
D51.8 Other vitamin B12 deficiency anaemias	0.363	0.637
M06.08 Seronegative rheumatoid arthritis (Other)	0.363	0.637
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.363	0.637
I13.1 Hypertensive heart and renal disease with renal failure	0.364	0.636
M12.3 Palindromic rheumatism	0.364	0.636
H34.8 Other retinal vascular occlusions	0.365	0.635
D89.3 Immune reconstitution syndrome	0.366	0.634
E14 Unspecified diabetes mellitus	0.366	0.634
I25.3 Aneurysm of heart	0.366	0.634
J85 Abscess of lung and mediastinum	0.368	0.632
D64.4 Congenital dyserythropoietic anaemia	0.368	0.631
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.368	0.631
D64.1 Secondary sideroblastic anaemia due to disease	0.368	0.631
E05.5 Thyroid crisis or storm	0.369	0.631
E05.4 Thyrotoxicosis factitia	0.369	0.631
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.369	0.631
D86.8 Sarcoidosis of other and combined sites	0.369	0.631
M08.9 Juvenile arthritis, unspecified	0.369	0.631
I11 Hypertensive heart disease	0.369	0.631
D89.9 Disorder involving the immune mechanism, unspecified	0.369	0.630
M08.0 Juvenile rheumatoid arthritis	0.370	0.630
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.372	0.628
S00 Superficial injury of head	0.373	0.627
M06.36 Rheumatoid nodule (Lower leg)	0.373	0.627
D63 Anaemia in chronic diseases classified elsewhere	0.374	0.626
D69.3 Idiopathic thrombocytopenic purpura	0.375	0.625
G70.9 Myoneural disorder, unspecified	0.375	0.624
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.376	0.624
I15.0 Renovascular hypertension	0.376	0.624
M12.24 Villonodular synovitis (pigmented) (Hand)	0.377	0.623
H35.8 Other specified retinal disorders	0.377	0.623
I13.9 Hypertensive heart and renal disease, unspecified	0.377	0.623
I15.2 Hypertension secondary to endocrine disorders	0.378	0.622
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.378	0.622
E75.5 Other lipid storage disorders	0.378	0.621
M13 Other arthritis	0.379	0.621
J32.3 Chronic sphenoidal sinusitis	0.379	0.621
E75.2 Other sphingolipidosis	0.379	0.621
G03 Meningitis due to other and unspecified causes	0.380	0.620
I22.8 Subsequent myocardial infarction of other sites	0.380	0.619
E66.1 Drug-induced obesity	0.381	0.619
E26 Hyperaldosteronism	0.382	0.618
I77.1 Stricture of artery	0.382	0.618
T20-T25 Burns and corrosions of external body surface, specified by site	0.383	0.617
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.383	0.617
J21.9 Acute bronchiolitis, unspecified	0.384	0.616
H31 Other disorders of choroid	0.385	0.615
H30 Chorioretinal inflammation	0.385	0.615
M06.04 Seronegative rheumatoid arthritis (Hand)	0.387	0.613
G00.1 Pneumococcal meningitis	0.387	0.613
J20.7 Acute bronchitis due to echovirus	0.388	0.612
J20.6 Acute bronchitis due to rhinovirus	0.388	0.612
J20.5 Acute bronchitis due to respiratory syncytial virus	0.388	0.612
J20.4 Acute bronchitis due to parainfluenza virus	0.388	0.612
J20.3 Acute bronchitis due to coxsackie virus	0.388	0.612
J20.2 Acute bronchitis due to streptococcus	0.388	0.612
J20.1 Acute bronchitis due to Haemophilus influenzae	0.388	0.612
J20.0 Acute bronchitis due to Mycoplasma pneumoniae	0.388	0.612
G62 Other polyneuropathies	0.390	0.610
M12.4 Intermittent hydrarthrosis	0.390	0.610
M12.1 Kaschin-Beck disease	0.390	0.610
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.390	0.610
E24 Cushing's syndrome	0.392	0.608
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.392	0.607
I74 Arterial embolism and thrombosis	0.393	0.607
H57 Other disorders of eye and adnexa	0.393	0.607
J12.1 Respiratory syncytial virus pneumonia	0.394	0.606
G06 Intracranial and intraspinal abscess and granuloma	0.394	0.606
J37 Chronic laryngitis and laryngotracheitis	0.395	0.605
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.395	0.605
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.395	0.605
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.395	0.604
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.395	0.604
S00.0 Superficial injury of scalp	0.397	0.603
E06.5 Other chronic thyroiditis	0.398	0.602
E31 Polyglandular dysfunction	0.399	0.601
D52.8 Other folate deficiency anaemias	0.400	0.600
D52.1 Drug-induced folate deficiency anaemia	0.400	0.600
D52.0 Dietary folate deficiency anaemia	0.400	0.600
D53.9 Nutritional anaemia, unspecified	0.400	0.600
E06.4 Drug-induced thyroiditis	0.401	0.599
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.401	0.599
E06.0 Acute thyroiditis	0.401	0.599
E27 Other disorders of adrenal gland	0.401	0.599
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.401	0.598
D84.1 Defects in the complement system	0.402	0.598
M63 Disorders of muscle in diseases classified elsewhere	0.403	0.597
M61 Calcification and ossification of muscle	0.403	0.597
G71 Primary disorders of muscles	0.404	0.596
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.404	0.596
G70.2 Congenital and developmental myasthenia	0.404	0.595
G70.1 Toxic myoneural disorders	0.404	0.595
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.405	0.595
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.405	0.595
M12.5 Traumatic arthropathy	0.405	0.595
M76.6 Achilles tendinitis	0.406	0.594
E72.0 Disorders of amino-acid transport	0.407	0.593
D83.9 Common variable immunodeficiency, unspecified	0.408	0.592
D56 Thalassaemia	0.408	0.592
E66.0 Obesity due to excess calories	0.408	0.592
D64.0 Hereditary sideroblastic anaemia	0.409	0.591
E88 Other metabolic disorders	0.409	0.590
E25 Adrenogenital disorders	0.410	0.590
J35 Chronic diseases of tonsils and adenoids	0.411	0.589
J17.8 Pneumonia in other diseases classified elsewhere	0.412	0.588
M12.8 Other specific arthropathies, not elsewhere classified	0.412	0.588
I77.9 Disorder of arteries and arterioles, unspecified	0.412	0.588
J95-J99 Other diseases of the respiratory system	0.412	0.588
S02.5 Fracture of tooth	0.413	0.587
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.414	0.586
E28.3 Primary ovarian failure	0.415	0.585
G04 Encephalitis, myelitis and encephalomyelitis	0.415	0.585
M86-M90 Other osteopathies	0.415	0.585
J18.8 Other pneumonia, organism unspecified	0.415	0.585
M60.99 Myositis, unspecified (Site unspecified)	0.416	0.584
D61 Other aplastic anaemias	0.419	0.581
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.420	0.580
E74.0 Glycogen storage disease	0.421	0.579
M08.8 Other juvenile arthritis	0.421	0.579
M08.4 Pauciarticular juvenile arthritis	0.421	0.579
M08.3 Juvenile polyarthritis (seronegative)	0.421	0.579
M08.2 Juvenile arthritis with systemic onset	0.421	0.579
M08.1 Juvenile ankylosing spondylitis	0.421	0.579
J84.8 Other specified interstitial pulmonary diseases	0.421	0.579
S20-S29 Injuries to the thorax	0.422	0.578
G64 Other disorders of peripheral nervous system	0.423	0.577
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.423	0.576
G30-G32 Other degenerative diseases of the nervous system	0.423	0.576
M06.88 Other specified rheumatoid arthritis (Other)	0.424	0.576
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.424	0.576
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.424	0.576
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.424	0.576
M06.84 Other specified rheumatoid arthritis (Hand)	0.424	0.576
M06.83 Other specified rheumatoid arthritis (Forearm)	0.424	0.576
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.424	0.576
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.424	0.576
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.424	0.576
G09 Sequelae of inflammatory diseases of central nervous system	0.424	0.575
J94 Other pleural conditions	0.425	0.575
S02.2 Fracture of nasal bones	0.425	0.575
E78.9 Disorder of lipoprotein metabolism, unspecified	0.425	0.574
E75.6 Lipid storage disorder, unspecified	0.426	0.574
E75.4 Neuronal ceroid lipofuscinosis	0.426	0.574
E75.3 Sphingolipidosis, unspecified	0.426	0.574
E75.1 Other gangliosidosis	0.426	0.574
E75.0 GM2 gangliosidosis	0.426	0.574
D69.9 Haemorrhagic condition, unspecified	0.426	0.574
J12.8 Other viral pneumonia	0.426	0.574
J12.3 Human metapneumovirus pneumonia	0.426	0.574
J12.0 Adenoviral pneumonia	0.426	0.574
M07.34 Other psoriatic arthropathies (Hand)	0.427	0.573
I15.8 Other secondary hypertension	0.429	0.571
G61 Inflammatory polyneuropathy	0.429	0.571
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.430	0.570
E72.9 Disorder of amino-acid metabolism, unspecified	0.431	0.569
E72.8 Other specified disorders of amino-acid metabolism	0.431	0.569
E72.5 Disorders of glycine metabolism	0.431	0.569
E72.4 Disorders of ornithine metabolism	0.431	0.569
E72.3 Disorders of lysine and hydroxylysine metabolism	0.431	0.569
E72.2 Disorders of urea cycle metabolism	0.431	0.569
J17.1 Pneumonia in viral diseases classified elsewhere	0.432	0.568
E87 Other disorders of fluid, electrolyte and acid-base balance	0.433	0.567
E20 Hypoparathyroidism	0.433	0.567
D57 Sickle-cell disorders	0.434	0.566
T20 Burn and corrosion of head and neck	0.435	0.565
I24.1 Dressler's syndrome	0.436	0.564

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations