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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12409334
log Bayes Factor = 13.2966
Chromosome 1   position 206,718,142  (GRCh37) Explore rs12409334 on Ensembl!
Variant rs12409334 is part of Cluster X0052

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.998 0.002 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.995 0.005 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.993 0.007 0.000
C15-C26 Malignant neoplasms of digestive organs
0.993 0.007 0.000
M25 Other joint disorders, not elsewhere classified
0.992 0.008 0.000
Z60 Problems related to social environment
0.992 0.008 0.000
D00-D09 In situ neoplasms
0.988 0.012 0.000
Z60.2 Living alone
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.986 0.014 0.000
C18 Malignant neoplasm of colon
0.984 0.016 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.978 0.022 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.969 0.031 0.000
S60-S69 Injuries to the wrist and hand
0.968 0.032 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.968 0.032 0.000
D05 Carcinoma in situ of breast
0.967 0.033 0.000
M65-M68 Disorders of synovium and tendon
0.964 0.036 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.962 0.038 0.000
O60-O75 Complications of labour and delivery
0.959 0.041 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.954 0.046 0.000
S50-S59 Injuries to the elbow and forearm
0.953 0.047 0.000
C18.9 Colon, unspecified
0.950 0.050 0.000
M25.4 Effusion of joint
0.950 0.050 0.000
D05.1 Intraductal carcinoma in situ
0.949 0.051 0.000
M65 Synovitis and tenosynovitis
0.940 0.060 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.938 0.062 0.000
M25.46 Effusion of joint (Lower leg)
0.929 0.071 0.000
M25.7 Osteophyte
0.925 0.075 0.000
S52 Fracture of forearm
0.916 0.084 0.000
Z13 Special screening examination for other diseases and disorders
0.916 0.084 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.911 0.089 0.000
S80-S89 Injuries to the knee and lower leg
0.911 0.089 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.911 0.089 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.911 0.089 0.000
O72 Postpartum haemorrhage
0.908 0.092 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.908 0.092 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.903 0.097 0.000
Z63 Other problems related to primary support group, including family circumstances
0.903 0.097 0.000
C18.3 Hepatic flexure
0.902 0.098 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.900 0.100 0.000
C79 Secondary malignant neoplasm of other sites
0.900 0.100 0.000
M35 Other systemic involvement of connective tissue
0.898 0.102 0.000
Z35 Supervision of high-risk pregnancy
0.898 0.102 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.897 0.103 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.895 0.105 0.000
M50-M54 Other dorsopathies
0.893 0.107 0.000
S64 Injury of nerves at wrist and hand level
0.892 0.108 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.892 0.108 0.000
M21 Other acquired deformities of limbs
0.891 0.109 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.888 0.111 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.887 0.112 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.887 0.113 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.877 0.123 0.000
W00-W19 Falls
0.877 0.123 0.000
Z13.9 Special screening examination, unspecified
0.877 0.123 0.000
T81 Complications of procedures, not elsewhere classified
0.877 0.123 0.000
S52.5 Fracture of lower end of radius
0.873 0.127 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.872 0.128 0.000
O72.1 Other immediate postpartum haemorrhage
0.869 0.131 0.000
D06 Carcinoma in situ of cervix uteri
0.869 0.131 0.000
O36 Maternal care for other known or suspected foetal problems
0.868 0.132 0.000
C51-C58 Malignant neoplasms of female genital organs
0.868 0.132 0.000
M20 Acquired deformities of fingers and toes
0.867 0.133 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.865 0.135 0.000
E70-E90 Metabolic disorders
0.865 0.135 0.000
M40-M43 Deforming dorsopathies
0.864 0.136 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.864 0.136 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.861 0.139 0.000
Y95 Nosocomial condition
0.858 0.142 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.849 0.151 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.848 0.152 0.000
M80-M85 Disorders of bone density and structure
0.848 0.152 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.847 0.153 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.843 0.157 0.000
S52.50 Fracture of lower end of radius (closed)
0.842 0.158 0.000
M50 Cervical disk disorders
0.842 0.158 0.000
S82 Fracture of lower leg, including ankle
0.840 0.160 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.840 0.160 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.839 0.161 0.000
M35.3 Polymyalgia rheumatica
0.839 0.161 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.834 0.166 0.000
L40-L45 Papulosquamous disorders
0.831 0.169 0.000
Z36 Antenatal screening
0.829 0.171 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.827 0.173 0.000
M25.76 Osteophyte (Lower leg)
0.827 0.173 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.824 0.176 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.824 0.176 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.823 0.177 0.000
Z03.8 Observation for other suspected diseases and conditions
0.819 0.181 0.000
M20.1 Hallux valgus (acquired)
0.817 0.183 0.000
C18.1 Appendix
0.816 0.184 0.000
Z34 Supervision of normal pregnancy
0.813 0.187 0.000
S68 Traumatic amputation of wrist and hand
0.813 0.187 0.000
M65.3 Trigger finger
0.812 0.188 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.812 0.188 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.804 0.196 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.801 0.199 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.801 0.199 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.801 0.199 0.000
Z64 Problems related to certain psychosocial circumstances
0.800 0.200 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.799 0.201 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.799 0.201 0.000
O63 Long labour
0.799 0.201 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.798 0.202 0.000
M24 Other specific joint derangements
0.797 0.203 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.796 0.204 0.000
C18.2 Ascending colon
0.796 0.204 0.000
Z01.8 Other specified special examinations
0.795 0.205 0.000
M22 Disorders of patella
0.794 0.206 0.000
L90 Atrophic disorders of skin
0.794 0.206 0.000
L40 Psoriasis
0.792 0.208 0.000
S64.4 Injury of digital nerve of other finger
0.791 0.209 0.000
M33 Dermatopolymyositis
0.789 0.211 0.000
Z58 Problems related to physical environment
0.789 0.211 0.000
O34.1 Maternal care for tumour of corpus uteri
0.788 0.212 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.787 0.213 0.000
E83 Disorders of mineral metabolism
0.787 0.213 0.000
C01 Malignant neoplasm of base of tongue
0.787 0.213 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.787 0.213 0.000
Z63.7 Other stressful life events affecting family and household
0.786 0.214 0.000
T66-T78 Other and unspecified effects of external causes
0.786 0.214 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.784 0.216 0.000
D06.9 Cervix, unspecified
0.783 0.217 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.783 0.217 0.000
O80-O84 Delivery
0.781 0.219 0.000
M05-M14 Inflammatory polyarthropathies
0.781 0.219 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.781 0.219 0.000
S82.3 Fracture of lower end of tibia
0.776 0.224 0.000
M25.0 Haemarthrosis
0.776 0.224 0.000
M86-M90 Other osteopathies
0.772 0.228 0.000
S10-S19 Injuries to the neck
0.770 0.230 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.769 0.231 0.000
O85-O92 Complications predominantly related to the puerperium
0.768 0.232 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.768 0.232 0.000
M15-M19 Arthrosis
0.766 0.234 0.000
C56 Malignant neoplasm of ovary
0.766 0.234 0.000
Z35.5 Supervision of elderly primigravida
0.765 0.235 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.765 0.235 0.000
M21.2 Flexion deformity
0.764 0.236 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.764 0.236 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.763 0.237 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.762 0.238 0.000
L90.5 Scar conditions and fibrosis of skin
0.762 0.238 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.762 0.238 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.760 0.240 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.759 0.241 0.000
O43 Placental disorders
0.759 0.241 0.000
M25.8 Other specified joint disorders
0.758 0.242 0.000
Z01.6 Radiological examination, not elsewhere classified
0.757 0.243 0.000
M50.2 Other cervical disk displacement
0.757 0.243 0.000
Z39 Postpartum care and examination
0.756 0.244 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.756 0.244 0.000
M84 Disorders of continuity of bone
0.756 0.244 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.754 0.246 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.754 0.246 0.000
M25.74 Osteophyte (Hand)
0.754 0.246 0.000
C80 Malignant neoplasm without specification of site
0.753 0.247 0.000
S52.0 Fracture of upper end of ulna
0.753 0.247 0.000
Z63.4 Disappearance and death of family member
0.753 0.247 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.753 0.247 0.000
L89 Decubitus ulcer
0.751 0.248 0.000
L40.9 Psoriasis, unspecified
0.750 0.250 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.750 0.250 0.000
M31 Other necrotising vasculopathies
0.750 0.250 0.000
C18.5 Splenic flexure
0.748 0.251 0.000
D03 Melanoma in situ
0.747 0.253 0.000
O16 Unspecified maternal hypertension
0.747 0.253 0.000
V10-V19 Pedal cyclist injured in transport accident
0.746 0.254 0.000
M60-M63 Disorders of muscles
0.745 0.255 0.000
Z33 Pregnant state, incidental
0.744 0.256 0.000
C26.0 Intestinal tract, part unspecified
0.744 0.256 0.000
S60 Superficial injury of wrist and hand
0.743 0.257 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.741 0.259 0.000
M50.0 Cervical disk disorder with myelopathy
0.741 0.259 0.000
V40-V49 Car occupant injured in transport accident
0.740 0.259 0.000
W19 Unspecified fall
0.740 0.260 0.000
C25 Malignant neoplasm of pancreas
0.736 0.264 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.736 0.264 0.000
S50 Superficial injury of forearm
0.734 0.265 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.734 0.266 0.000
O00-O08 Pregnancy with abortive outcome
0.734 0.266 0.000
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified
0.734 0.266 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.732 0.268 0.000
O40 Polyhydramnios
0.731 0.269 0.000
S69 Other and unspecified injuries of wrist and hand
0.731 0.269 0.000
S82.30 Fracture of lower end of tibia (closed)
0.731 0.269 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.730 0.270 0.000
Z32 Pregnancy examination and test
0.728 0.271 0.000
M53 Other dorsopathies, not elsewhere classified
0.728 0.272 0.000
E50-E64 Other nutritional deficiencies
0.726 0.274 0.000
Z34.8 Supervision of other normal pregnancy
0.726 0.274 0.000
M16 Coxarthrosis [arthrosis of hip]
0.725 0.275 0.000
Chapter XXII Codes for special purposes
0.724 0.275 0.000
D05.0 Lobular carcinoma in situ
0.723 0.277 0.000
S70-S79 Injuries to the hip and thigh
0.723 0.277 0.000
X60-X84 Intentional self-harm
0.722 0.278 0.000
M34 Systemic sclerosis
0.722 0.278 0.000
O71 Other obstetric trauma
0.721 0.279 0.000
M65.34 Trigger finger-Hand
0.721 0.279 0.000
M25.9 Joint disorder, unspecified
0.720 0.280 0.000
Z01.9 Special examination, unspecified
0.720 0.280 0.000
S62 Fracture at wrist and hand level
0.719 0.281 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
D04 Carcinoma in situ of skin
0.716 0.284 0.000
O63.0 Prolonged first stage (of labour)
0.716 0.284 0.000
Z65 Problems related to other psychosocial circumstances
0.715 0.284 0.000
Z62 Other problems related to upbringing
0.715 0.284 0.000
Z61 Problems related to negative life events in childhood
0.715 0.284 0.000
Z59 Problems related to housing and economic circumstances
0.715 0.284 0.000
Z56 Problems related to employment and unemployment
0.715 0.284 0.000
Z55 Problems related to education and literacy
0.715 0.284 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.715 0.285 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.715 0.285 0.000
O61 Failed induction of labour
0.715 0.285 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.715 0.285 0.000
O44 Placenta praevia
0.715 0.285 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.715 0.285 0.000
C18.0 Caecum
0.714 0.286 0.000
O45 Premature separation of placenta [abruptio placentae]
0.713 0.287 0.000
O33 Maternal care for known or suspected disproportion
0.713 0.287 0.000
O31 Complications specific to multiple gestation
0.713 0.287 0.000
O36.6 Maternal care for excessive foetal growth
0.713 0.287 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.713 0.287 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.713 0.287 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
Z10 Routine general health check-up of defined subpopulation
0.712 0.288 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.712 0.288 0.000
C21 Malignant neoplasm of anus and anal canal
0.712 0.288 0.000
C17 Malignant neoplasm of small intestine
0.712 0.288 0.000
C23 Malignant neoplasm of gallbladder
0.712 0.288 0.000
M41 Scoliosis
0.711 0.289 0.000
M25.3 Other instability of joint
0.711 0.289 0.000
M25.2 Flail joint
0.711 0.289 0.000
M25.1 Fistula of joint
0.711 0.289 0.000
Z60.9 Problem related to social environment, unspecified
0.711 0.289 0.000
Z60.8 Other problems related to social environment
0.711 0.289 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.711 0.289 0.000
Z60.4 Social exclusion and rejection
0.711 0.289 0.000
Z60.3 Acculturation difficulty
0.711 0.289 0.000
Z60.1 Atypical parenting situation
0.711 0.289 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.711 0.289 0.000
Z13.5 Special screening examination for eye and ear disorders
0.711 0.289 0.000
S52.8 Fracture of other parts of forearm
0.711 0.289 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.709 0.291 0.000
M43 Other deforming dorsopathies
0.709 0.291 0.000
S89 Other and unspecified injuries of lower leg
0.709 0.291 0.000
C15 Malignant neoplasm of oesophagus
0.709 0.291 0.000
D09 Carcinoma in situ of other and unspecified sites
0.708 0.292 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.708 0.292 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.708 0.292 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.292 0.000
Y10-Y34 Event of undetermined intent
0.707 0.292 0.000
Y00-Y09 Assault
0.707 0.292 0.000
X85-X99 Assault
0.707 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.707 0.292 0.000
X50-X57 Overexertion, travel and privation
0.707 0.292 0.000
X30-X39 Exposure to forces of nature
0.707 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.707 0.292 0.000
X10-X19 Contact with heat and hot substances
0.707 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.292 0.000
W75-W84 Other accidental threats to breathing
0.707 0.292 0.000
W65-W74 Accidental drowning and submersion
0.707 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.707 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.292 0.000
V95-V97 Air and space transport accidents
0.707 0.292 0.000
V90-V94 Water transport accidents
0.707 0.292 0.000
V80-V89 Other land transport accidents
0.707 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.292 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.707 0.293 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.707 0.293 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.707 0.293 0.000
O34.6 Maternal care for abnormality of vagina
0.707 0.293 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.707 0.293 0.000
O34.4 Maternal care for other abnormalities of cervix
0.707 0.293 0.000
O34.3 Maternal care for cervical incompetence
0.707 0.293 0.000
O34.0 Maternal care for congenital malformation of uterus
0.707 0.293 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.707 0.293 0.000
S64.3 Injury of digital nerve of thumb
0.707 0.293 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.706 0.294 0.000
O32.0 Maternal care for unstable lie
0.706 0.294 0.000
C18.8 Overlapping lesion of colon
0.706 0.294 0.000
W18 Other fall on same level
0.706 0.294 0.000
D48.1 Connective and other soft tissue
0.705 0.295 0.000
O30 Multiple gestation
0.705 0.295 0.000
S52.6 Fracture of lower end of both ulna and radius
0.704 0.296 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.703 0.297 0.000
O66 Other obstructed labour
0.703 0.297 0.000
E20-E35 Disorders of other endocrine glands
0.703 0.297 0.000
Y84.2 Radiological procedure and radiotherapy
0.702 0.298 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.702 0.298 0.000
M45-M49 Spondylopathies
0.702 0.298 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.701 0.299 0.000
S32 Fracture of lumbar spine and pelvis
0.700 0.300 0.000
L40.0 Psoriasis vulgaris
0.699 0.301 0.000
E65-E68 Obesity and other hyperalimentation
0.698 0.301 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.698 0.301 0.000
C18.6 Descending colon
0.698 0.302 0.000
Z38 Liveborn infants according to place of birth
0.695 0.305 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.694 0.305 0.000
S67 Crushing injury of wrist and hand
0.694 0.306 0.000
S65 Injury of blood vessels at wrist and hand level
0.694 0.306 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.694 0.306 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.694 0.306 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.694 0.306 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.694 0.306 0.000
D05.7 Other carcinoma in situ of breast
0.693 0.307 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.692 0.308 0.000
Z22 Carrier of infectious disease
0.692 0.308 0.000
L85 Other epidermal thickening
0.692 0.308 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.691 0.309 0.000
M66 Spontaneous rupture of synovium and tendon
0.691 0.309 0.000
W17 Other fall from one level to another
0.691 0.309 0.000
T87 Complications peculiar to reattachment and amputation
0.690 0.310 0.000
T86 Failure and rejection of transplanted organs and tissues
0.690 0.310 0.000
M06 Other rheumatoid arthritis
0.690 0.310 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.689 0.311 0.000
O62 Abnormalities of forces of labour
0.688 0.312 0.000
O74 Complications of anaesthesia during labour and delivery
0.688 0.312 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.688 0.312 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.688 0.312 0.000
O60 Preterm delivery
0.688 0.312 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.687 0.313 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.686 0.314 0.000
O36.9 Maternal care for foetal problem, unspecified
0.686 0.314 0.000
Z30 Contraceptive management
0.686 0.314 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.685 0.315 0.000
M21.1 Varus deformity, not elsewhere classified
0.685 0.315 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.685 0.315 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.684 0.316 0.000
Z09.4 Follow-up examination after treatment of fracture
0.684 0.316 0.000
Z09.3 Follow-up examination after psychotherapy
0.684 0.316 0.000
S59 Other and unspecified injuries of forearm
0.683 0.317 0.000
S58 Traumatic amputation of forearm
0.683 0.317 0.000
S57 Crushing injury of forearm
0.683 0.317 0.000
S56 Injury of muscle and tendon at forearm level
0.683 0.317 0.000
S55 Injury of blood vessels at forearm level
0.683 0.317 0.000
S54 Injury of nerves at forearm level
0.683 0.317 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.683 0.317 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.683 0.317 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.682 0.318 0.000
M25.49 Effusion of joint (Site unspecified)
0.681 0.319 0.000
M25.48 Effusion of joint (Other)
0.681 0.319 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.681 0.319 0.000
M25.44 Effusion of joint (Hand)
0.681 0.319 0.000
M25.43 Effusion of joint (Forearm)
0.681 0.319 0.000
M25.42 Effusion of joint (Upper arm)
0.681 0.319 0.000
M25.41 Effusion of joint (Shoulder region)
0.681 0.319 0.000
M25.40 Effusion of joint (Multiple sites)
0.681 0.319 0.000
M22.4 Chondromalacia patellae
0.681 0.319 0.000
D45 Polycythaemia vera
0.680 0.320 0.000
T79-T79 Certain early complications of trauma
0.680 0.320 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.680 0.320 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.680 0.320 0.000
O36.5 Maternal care for poor foetal growth
0.680 0.320 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.679 0.321 0.000
T90 Sequelae of injuries of head
0.677 0.323 0.000
O41 Other disorders of amniotic fluid and membranes
0.676 0.324 0.000
S90-S99 Injuries to the ankle and foot
0.676 0.324 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.675 0.325 0.000
E73 Lactose intolerance
0.674 0.326 0.000
M65.8 Other synovitis and tenosynovitis
0.674 0.326 0.000
M65.2 Calcific tendinitis
0.674 0.326 0.000
M65.1 Other infective (teno)synovitis
0.674 0.326 0.000
M65.0 Abscess of tendon sheath
0.674 0.326 0.000
M67 Other disorders of synovium and tendon
0.674 0.326 0.000
C09 Malignant neoplasm of tonsil
0.674 0.326 0.000
Z31 Procreative management
0.673 0.326 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.673 0.326 0.000
M21.24 Flexion deformity (Hand)
0.673 0.327 0.000
C18.4 Transverse colon
0.673 0.327 0.000
M50.3 Other cervical disk degeneration
0.673 0.327 0.000
Z04 Examination and observation for other reasons
0.672 0.328 0.000
S81 Open wound of lower leg
0.672 0.328 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.672 0.328 0.000
V20-V29 Motorcycle rider injured in transport accident
0.672 0.328 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.672 0.328 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.672 0.328 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.672 0.328 0.000
O72.0 Third-stage haemorrhage
0.672 0.328 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.672 0.328 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.671 0.329 0.000
C79.6 Secondary malignant neoplasm of ovary
0.668 0.332 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.667 0.332 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.667 0.333 0.000
T91 Sequelae of injuries of neck and trunk
0.666 0.334 0.000
Q50-Q56 Congenital malformations of genital organs
0.666 0.334 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.664 0.336 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.664 0.336 0.000
M25.79 Osteophyte (Site unspecified)
0.663 0.336 0.000
M25.73 Osteophyte (Forearm)
0.663 0.336 0.000
M25.72 Osteophyte (Upper arm)
0.663 0.336 0.000
M25.71 Osteophyte (Shoulder region)
0.663 0.336 0.000
M25.70 Osteophyte (Multiple sites)
0.663 0.336 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.663 0.337 0.000
Z75 Problems related to medical facilities and other health care
0.662 0.338 0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.661 0.338 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.661 0.338 0.000
E83.3 Disorders of phosphorus metabolism
0.661 0.339 0.000
M20.2 Hallux rigidus
0.661 0.339 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.660 0.340 0.000
Z64.0 Problems related to unwanted pregnancy
0.658 0.342 0.000
T92 Sequelae of injuries of upper limb
0.658 0.342 0.000
S52.9 Fracture of forearm, part unspecified
0.657 0.343 0.000
S52.7 Multiple fractures of forearm
0.657 0.343 0.000
S52.4 Fracture of shafts of both ulna and radius
0.657 0.343 0.000
S52.3 Fracture of shaft of radius
0.657 0.343 0.000
S52.2 Fracture of shaft of ulna
0.657 0.343 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.657 0.343 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.657 0.343 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.657 0.343 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.657 0.343 0.000
Z13.2 Special screening examination for nutritional disorders
0.657 0.343 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.657 0.343 0.000
Z36.8 Other antenatal screening
0.656 0.344 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.655 0.345 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.655 0.345 0.000
E83.5 Disorders of calcium metabolism
0.655 0.345 0.000
Z29 Need for other prophylactic measures
0.655 0.345 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.653 0.346 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.653 0.346 0.000
Y98 Lifestyle-related condition
0.653 0.346 0.000
Y97 Environmental-pollution-related condition
0.653 0.346 0.000
Y96 Work-related condition
0.653 0.346 0.000
S88 Traumatic amputation of lower leg
0.653 0.346 0.000
S87 Crushing injury of lower leg
0.653 0.346 0.000
S86 Injury of muscle and tendon at lower leg level
0.653 0.346 0.000
S85 Injury of blood vessels at lower leg level
0.653 0.346 0.000
S84 Injury of nerves at lower leg level
0.653 0.346 0.000
D80-D89 Certain disorders involving the immune mechanism
0.653 0.347 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.653 0.347 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.653 0.347 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.653 0.347 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.653 0.347 0.000
Z01.3 Examination of blood pressure
0.653 0.347 0.000
Z01.2 Dental examination
0.653 0.347 0.000
Z01.1 Examination of ears and hearing
0.653 0.347 0.000
Z01.0 Examination of eyes and vision
0.653 0.347 0.000
S40-S49 Injuries to the shoulder and upper arm
0.653 0.347 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.652 0.348 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.652 0.348 0.000
O72.3 Postpartum coagulation defects
0.651 0.349 0.000
Y48 Anaesthetics and therapeutic gases
0.651 0.349 0.000
T51 Toxic effect of alcohol
0.651 0.349 0.000
S51 Open wound of forearm
0.650 0.350 0.000
Q60-Q64 Congenital malformations of the urinary system
0.649 0.351 0.000
Z76 Persons encountering health services in other circumstances
0.649 0.351 0.000
S61 Open wound of wrist and hand
0.648 0.352 0.000
Z74 Problems related to care-provider dependency
0.648 0.352 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.648 0.352 0.000
C13 Malignant neoplasm of hypopharynx
0.648 0.352 0.000
C11 Malignant neoplasm of nasopharynx
0.648 0.352 0.000
C10 Malignant neoplasm of oropharynx
0.648 0.352 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.648 0.352 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.648 0.352 0.000
C05 Malignant neoplasm of palate
0.648 0.352 0.000
C04 Malignant neoplasm of floor of mouth
0.648 0.352 0.000
C03 Malignant neoplasm of gum
0.648 0.352 0.000
C00 Malignant neoplasm of lip
0.648 0.352 0.000
C12 Malignant neoplasm of pyriform sinus
0.648 0.352 0.000
C07 Malignant neoplasm of parotid gland
0.648 0.352 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.648 0.352 0.000
Z63.9 Problem related to primary support group, unspecified
0.647 0.353 0.000
Z63.8 Other specified problems related to primary support group
0.647 0.353 0.000
Z63.6 Dependent relative needing care at home
0.647 0.353 0.000
Z63.5 Disruption of family by separation and divorce
0.647 0.353 0.000
Z63.3 Absence of family member
0.647 0.353 0.000
Z63.2 Inadequate family support
0.647 0.353 0.000
Z63.1 Problems in relationship with parents and in-laws
0.647 0.353 0.000
S82.2 Fracture of shaft of tibia
0.646 0.353 0.000
Z63.0 Problems in relationship with spouse or partner
0.646 0.354 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.646 0.354 0.000
E86 Volume depletion
0.646 0.354 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.645 0.355 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.645 0.355 0.000
L90.0 Lichen sclerosus et atrophicus
0.644 0.356 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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