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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12452225
log Bayes Factor = 2.83101
Chromosome 17   position 33,266,431  (GRCh37) Explore rs12452225 on Ensembl!
Variant rs12452225 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
T36-T50 Poisoning by drugs, medicaments and biological substances
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.981 0.019 0.000
S00-S09 Injuries to the head
0.969 0.031 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.967 0.033 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.963 0.037 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.949 0.051 0.000
S01 Open wound of head
0.948 0.052 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.946 0.054 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.937 0.063 0.000
T40.2 Other opioids
0.931 0.069 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.928 0.072 0.000
T39.0 Salicylates
0.928 0.072 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.924 0.076 0.000
D68 Other coagulation defects
0.907 0.093 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.903 0.097 0.000
S02 Fracture of skull and facial bones
0.893 0.107 0.000
D68.2 Hereditary deficiency of other clotting factors
0.887 0.113 0.000
D69 Purpura and other haemorrhagic conditions
0.887 0.113 0.000
S90-S99 Injuries to the ankle and foot
0.870 0.130 0.000
T39.1 4-Aminophenol derivatives
0.870 0.130 0.000
S01.1 Open wound of eyelid and periocular area
0.869 0.131 0.000
T51 Toxic effect of alcohol
0.864 0.136 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.861 0.139 0.000
D68.8 Other specified coagulation defects
0.860 0.140 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.858 0.142 0.000
F10.2 Dependence syndrome
0.855 0.145 0.000
T42.4 Benzodiazepines
0.849 0.151 0.000
D69.6 Thrombocytopenia, unspecified
0.848 0.152 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.846 0.154 0.000
F10.0 Acute intoxication
0.844 0.156 0.000
Chapter V Mental and behavioural disorders
0.838 0.162 0.000
# Top node
0.836 0.164 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.836 0.164 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.826 0.174 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.825 0.175 0.000
S01.5 Open wound of lip and oral cavity
0.822 0.178 0.000
S01.4 Open wound of cheek and temporomandibular area
0.815 0.185 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.814 0.186 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.808 0.192 0.000
T66-T78 Other and unspecified effects of external causes
0.805 0.195 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.801 0.199 0.000
D68.5 Primary Thrombophilia
0.799 0.201 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.789 0.211 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.783 0.217 0.000
T51.9 Alcohol, unspecified
0.779 0.221 0.000
Chapter VII Diseases of the eye and adnexa
0.776 0.224 0.000
Q50-Q56 Congenital malformations of genital organs
0.773 0.227 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.770 0.230 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.767 0.233 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.766 0.234 0.000
Chapter XX External causes of morbidity and mortality
0.766 0.234 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.760 0.240 0.000
S01.0 Open wound of scalp
0.759 0.241 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.755 0.245 0.000
D68.9 Coagulation defect, unspecified
0.753 0.247 0.000
S05 Injury of eye and orbit
0.752 0.248 0.000
T59 Toxic effect of other gases, fumes and vapours
0.750 0.250 0.000
H30-H36 Disorders of choroid and retina
0.747 0.253 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.746 0.254 0.000
X60-X84 Intentional self-harm
0.745 0.255 0.000
S02.3 Fracture of orbital floor
0.742 0.257 0.000
S01.9 Open wound of head, part unspecified
0.742 0.258 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.740 0.260 0.000
S92 Fracture of foot, except ankle
0.740 0.260 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.740 0.260 0.000
T00-T07 Injuries involving multiple body regions
0.739 0.261 0.000
H35 Other retinal disorders
0.736 0.264 0.000
S00 Superficial injury of head
0.734 0.266 0.000
T36 Poisoning by systemic antibiotics
0.733 0.266 0.000
T51.0 Ethanol
0.733 0.267 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.724 0.276 0.000
S80-S89 Injuries to the knee and lower leg
0.723 0.277 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.719 0.281 0.000
T23 Burn and corrosion of wrist and hand
0.718 0.282 0.000
S01.8 Open wound of other parts of head
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
S91 Open wound of ankle and foot
0.714 0.286 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.713 0.287 0.000
S40-S49 Injuries to the shoulder and upper arm
0.712 0.288 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.712 0.288 0.000
Q51 Congenital malformations of uterus and cervix
0.711 0.289 0.000
S70-S79 Injuries to the hip and thigh
0.710 0.290 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.709 0.291 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.708 0.291 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.707 0.293 0.000
S97 Crushing injury of ankle and foot
0.706 0.294 0.000
S01.7 Multiple open wounds of head
0.705 0.295 0.000
F11 Mental and behavioural disorders due to use of opioids
0.705 0.295 0.000
T33-T35 Frostbite
0.703 0.296 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.703 0.296 0.000
H35.3 Degeneration of macula and posterior pole
0.703 0.297 0.000
F10.9 Unspecified mental and behavioural disorder
0.701 0.299 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.701 0.299 0.000
Q80-Q89 Other congenital malformations
0.700 0.300 0.000
S02.1 Fracture of base of skull
0.695 0.305 0.000
S08 Traumatic amputation of part of head
0.695 0.305 0.000
S07 Crushing injury of head
0.695 0.305 0.000
S04 Injury of cranial nerves
0.695 0.305 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.695 0.305 0.000
S09 Other and unspecified injuries of head
0.695 0.305 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.694 0.306 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.694 0.306 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.694 0.306 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.694 0.306 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.694 0.306 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.694 0.306 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.694 0.306 0.000
T44.0 Anticholinesterase agents
0.694 0.306 0.000
T42.1 Iminostilbenes
0.692 0.308 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.690 0.310 0.000
T39.4 Antirheumatics, not elsewhere classified
0.690 0.310 0.000
T39.2 Pyrazolone derivatives
0.690 0.310 0.000
F10.4 Withdrawal state with delirium
0.690 0.310 0.000
T56 Toxic effect of metals
0.689 0.311 0.000
S02.5 Fracture of tooth
0.686 0.313 0.000
D68.0 Von Willebrand's disease
0.686 0.314 0.000
X62.9 Unspecified place
0.684 0.316 0.000
S02.2 Fracture of nasal bones
0.681 0.319 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.681 0.319 0.000
T40.8 Lysergide [LSD]
0.681 0.319 0.000
T40.7 Cannabis (derivatives)
0.681 0.319 0.000
T40.5 Cocaine
0.681 0.319 0.000
T40.3 Methadone
0.681 0.319 0.000
T40.1 Heroin
0.681 0.319 0.000
T40.0 Opium
0.681 0.319 0.000
T43.2 Other and unspecified antidepressants
0.680 0.320 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.678 0.322 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.678 0.322 0.000
T42.3 Barbiturates
0.678 0.322 0.000
T42.2 Succinimides and oxazolidinediones
0.678 0.322 0.000
T42.0 Hydantoin derivatives
0.678 0.322 0.000
T63 Toxic effect of contact with venomous animals
0.678 0.322 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.678 0.322 0.000
S02.7 Multiple fractures involving skull and facial bones
0.677 0.323 0.000
S02.4 Fracture of malar and maxillary bones
0.673 0.327 0.000
D69.9 Haemorrhagic condition, unspecified
0.672 0.328 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.670 0.330 0.000
T65 Toxic effect of other and unspecified substances
0.665 0.334 0.000
T62 Toxic effect of other noxious substances eaten as food
0.665 0.334 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.665 0.334 0.000
T60 Toxic effect of pesticides
0.665 0.334 0.000
T57 Toxic effect of other inorganic substances
0.665 0.334 0.000
T54 Toxic effect of corrosive substances
0.665 0.334 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.665 0.334 0.000
T52 Toxic effect of organic solvents
0.665 0.334 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.665 0.334 0.000
T55 Toxic effect of soaps and detergents
0.665 0.334 0.000
F43 Reaction to severe stress, and adjustment disorders
0.664 0.336 0.000
S02.8 Fractures of other skull and facial bones
0.664 0.336 0.000
T43.9 Psychotropic drug, unspecified
0.663 0.337 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.663 0.337 0.000
T43.6 Psychostimulants with abuse potential
0.663 0.337 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.663 0.337 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.663 0.337 0.000
T58 Toxic effect of carbon monoxide
0.662 0.338 0.000
H35.0 Background retinopathy and retinal vascular changes
0.660 0.340 0.000
D66 Hereditary factor VIII deficiency
0.658 0.341 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.658 0.342 0.000
F10.3 Withdrawal state
0.655 0.345 0.000
S01.3 Open wound of ear
0.654 0.346 0.000
W50-W64 Exposure to animate mechanical forces
0.652 0.348 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.652 0.348 0.000
Q51.3 Bicornate uterus
0.652 0.348 0.000
T79-T79 Certain early complications of trauma
0.651 0.349 0.000
D68.6 Other Thrombophilia
0.650 0.349 0.000
D68.4 Acquired coagulation factor deficiency
0.650 0.349 0.000
D68.1 Hereditary factor XI deficiency
0.650 0.349 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.649 0.351 0.000
T68 Hypothermia
0.648 0.352 0.000
T45.0 Antiallergic and antiemetic drugs
0.648 0.352 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.647 0.352 0.000
D67 Hereditary factor IX deficiency
0.647 0.353 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.647 0.353 0.000
T21 Burn and corrosion of trunk
0.646 0.354 0.000
S02.0 Fracture of vault of skull
0.645 0.355 0.000
T38.1 Thyroid hormones and substitutes
0.643 0.357 0.000
Q66 Congenital deformities of feet
0.643 0.357 0.000
W00-W19 Falls
0.640 0.360 0.000
S10-S19 Injuries to the neck
0.639 0.361 0.000
H18 Other disorders of cornea
0.638 0.362 0.000
F80-F89 Disorders of psychological development
0.637 0.363 0.000
H21 Other disorders of iris and ciliary body
0.637 0.363 0.000
D69.8 Other specified haemorrhagic conditions
0.636 0.364 0.000
D69.4 Other primary thrombocytopenia
0.636 0.364 0.000
D69.2 Other nonthrombocytopenic purpura
0.636 0.364 0.000
D69.1 Qualitative platelet defects
0.636 0.364 0.000
D69.0 Allergic purpura
0.636 0.364 0.000
T20 Burn and corrosion of head and neck
0.636 0.364 0.000
S02.30 Fracture of orbital floor (closed)
0.634 0.366 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.633 0.367 0.000
Q52 Other congenital malformations of female genitalia
0.632 0.368 0.000
T17 Foreign body in respiratory tract
0.628 0.372 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.626 0.374 0.000
D69.5 Secondary thrombocytopenia
0.626 0.374 0.000
F44 Dissociative [conversion] disorders
0.625 0.375 0.000
H53-H54 Visual disturbances and blindness
0.625 0.375 0.000
Q54 Hypospadias
0.624 0.376 0.000
S89 Other and unspecified injuries of lower leg
0.624 0.376 0.000
S98 Traumatic amputation of ankle and foot
0.624 0.376 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.624 0.376 0.000
S95 Injury of blood vessels at ankle and foot level
0.624 0.376 0.000
S94 Injury of nerves at ankle and foot level
0.624 0.376 0.000
T75 Effects of other external causes
0.624 0.376 0.000
F43.2 Adjustment disorders
0.624 0.376 0.000
H43-H45 Disorders of vitreous body and globe
0.622 0.378 0.000
T59.8 Other specified gases, fumes and vapours
0.622 0.378 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.622 0.378 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.621 0.379 0.000
T51.8 Other alcohols
0.620 0.380 0.000
T51.3 Fusel oil
0.620 0.380 0.000
T51.2 2-Propanol
0.620 0.380 0.000
T51.1 Methanol
0.620 0.380 0.000
T14 Injury of unspecified body region
0.619 0.381 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.618 0.382 0.000
F70-F79 Mental retardation
0.618 0.382 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.618 0.382 0.000
F10.8 Other mental and behavioural disorders
0.617 0.383 0.000
F10.7 Residual and late-onset psychotic disorder
0.617 0.383 0.000
F10.6 Amnesic syndrome
0.617 0.383 0.000
F10.5 Psychotic disorder
0.617 0.383 0.000
T25 Burn and corrosion of ankle and foot
0.615 0.385 0.000
H46 Optic neuritis
0.615 0.385 0.000
S92.4 Fracture of great toe
0.614 0.386 0.000
S86 Injury of muscle and tendon at lower leg level
0.612 0.388 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.612 0.388 0.000
S99 Other and unspecified injuries of ankle and foot
0.611 0.389 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.606 0.393 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.606 0.393 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.606 0.393 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.606 0.393 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.606 0.393 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.606 0.393 0.000
S05.1 Contusion of eyeball and orbital tissues
0.606 0.394 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.604 0.396 0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.604 0.396 0.000
T23.2 Burn of second degree of wrist and hand
0.603 0.396 0.000
H31 Other disorders of choroid
0.602 0.398 0.000
Y52 Agents primarily affecting the cardiovascular system
0.602 0.398 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.601 0.399 0.000
S20-S29 Injuries to the thorax
0.600 0.400 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.600 0.400 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.600 0.400 0.000
T40.6 Other and unspecified narcotics
0.599 0.401 0.000
D55-D59 Haemolytic anaemias
0.598 0.402 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.596 0.404 0.000
H35.4 Peripheral retinal degeneration
0.595 0.405 0.000
S91.1 Open wound of toe(s) without damage to nail
0.594 0.406 0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.593 0.407 0.000
H34 Retinal vascular occlusions
0.593 0.407 0.000
T38.9 Other and unspecified hormone antagonists
0.592 0.407 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.592 0.407 0.000
T38.7 Androgens and anabolic congeners
0.592 0.407 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.592 0.407 0.000
T38.5 Other oestrogens and progestogens
0.592 0.407 0.000
T38.4 Oral contraceptives
0.592 0.407 0.000
T38.2 Antithyroid drugs
0.592 0.407 0.000
T38.0 Glucocorticoids and synthetic analogues
0.592 0.407 0.000
F29 Unspecified nonorganic psychosis
0.592 0.408 0.000
Q00-Q07 Congenital malformations of the nervous system
0.592 0.408 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.590 0.410 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.590 0.410 0.000
S97.8 Crushing injury of other parts of ankle and foot
0.588 0.412 0.000
H35.5 Hereditary retinal dystrophy
0.588 0.412 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.584 0.416 0.000
Q35-Q37 Cleft lip and cleft palate
0.584 0.416 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.584 0.416 0.000
E20-E35 Disorders of other endocrine glands
0.583 0.417 0.000
F48 Other neurotic disorders
0.581 0.419 0.000
H18.2 Other corneal oedema
0.581 0.419 0.000
T45.5 Anticoagulants
0.580 0.420 0.000
X63.0 Home
0.578 0.422 0.000
T74 Maltreatment syndromes
0.577 0.423 0.000
T73 Effects of other deprivation
0.577 0.423 0.000
T70 Effects of air pressure and water pressure
0.577 0.423 0.000
T69 Other effects of reduced temperature
0.577 0.423 0.000
T67 Effects of heat and light
0.577 0.423 0.000
T71 Asphyxiation
0.577 0.423 0.000
T66 Unspecified effects of radiation
0.577 0.423 0.000
X10-X19 Contact with heat and hot substances
0.577 0.423 0.000
V01-V09 Pedestrian injured in transport accident
0.575 0.425 0.000
S92.5 Fracture of other toe
0.575 0.425 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.574 0.425 0.000
T45.8 Other primarily systemic and haematological agents
0.574 0.425 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.574 0.425 0.000
T45.6 Fibrinolysis-affecting drugs
0.574 0.425 0.000
T45.4 Iron and its compounds
0.574 0.425 0.000
T45.3 Enzymes, not elsewhere classified
0.574 0.425 0.000
T45.2 Vitamins, not elsewhere classified
0.574 0.425 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.574 0.426 0.000
T78 Adverse effects, not elsewhere classified
0.573 0.427 0.000
H30 Chorioretinal inflammation
0.573 0.427 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.571 0.429 0.000
H17 Corneal scars and opacities
0.570 0.430 0.000
T23.1 Burn of first degree of wrist and hand
0.570 0.430 0.000
F20 Schizophrenia
0.570 0.430 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.569 0.431 0.000
H16 Keratitis
0.569 0.431 0.000
F11.3 Withdrawal state
0.567 0.433 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.567 0.433 0.000
X20-X29 Contact with venomous animals and plants
0.566 0.434 0.000
V10-V19 Pedal cyclist injured in transport accident
0.566 0.434 0.000
T40.4 Other synthetic narcotics
0.566 0.434 0.000
T00 Superficial injuries involving multiple body regions
0.566 0.434 0.000
T46.1 Calcium-channel blockers
0.565 0.435 0.000
H20 Iridocyclitis
0.565 0.435 0.000
Q65 Congenital deformities of hip
0.564 0.436 0.000
S81 Open wound of lower leg
0.563 0.437 0.000
K81 Cholecystitis
0.563 0.437 0.000
S92.7 Multiple fractures of foot
0.561 0.438 0.000
W08 Fall involving other furniture
0.560 0.440 0.000
F11.2 Dependence syndrome
0.559 0.441 0.000
Q51.2 Other doubling of uterus
0.558 0.442 0.000
Q85 Phakomatoses, not elsewhere classified
0.557 0.443 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.557 0.443 0.000
H21.0 Hyphaema
0.557 0.443 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.555 0.445 0.000
S00.8 Superficial injury of other parts of head
0.555 0.445 0.000
S00.5 Superficial injury of lip and oral cavity
0.555 0.445 0.000
Y00-Y09 Assault
0.555 0.445 0.000
F45 Somatoform disorders
0.554 0.446 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.554 0.446 0.000
Q55 Other congenital malformations of male genital organs
0.554 0.446 0.000
S02.10 Fracture of base of skull (closed)
0.553 0.447 0.000
S90 Superficial injury of ankle and foot
0.553 0.447 0.000
S89.9 Unspecified injury of lower leg
0.553 0.447 0.000
Y52.1 Calcium-channel blockers
0.553 0.447 0.000
Chapter XI Diseases of the digestive system
0.553 0.447 0.000
Chapter VIII Diseases of the ear and mastoid process
0.552 0.448 0.000
T13 Other injuries of lower limb, level unspecified
0.552 0.448 0.000
T11 Other injuries of upper limb, level unspecified
0.552 0.448 0.000
T09 Other injuries of spine and trunk, level unspecified
0.552 0.448 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.552 0.448 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.552 0.448 0.000
T12 Fracture of lower limb, level unspecified
0.552 0.448 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.552 0.448 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.552 0.448 0.000
T10 Fracture of upper limb, level unspecified
0.552 0.448 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.552 0.448 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.552 0.448 0.000
T08 Fracture of spine, level unspecified
0.552 0.448 0.000
Q89 Other congenital malformations, not elsewhere classified
0.552 0.448 0.000
K81.0 Acute cholecystitis
0.552 0.448 0.000
Y77 Ophthalmic devices associated with adverse incidents
0.551 0.449 0.000
H18.5 Hereditary corneal dystrophies
0.550 0.450 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.550 0.450 0.000
Y35-Y36 Legal intervention and operations of war
0.549 0.450 0.000
Y10-Y34 Event of undetermined intent
0.549 0.450 0.000
X85-X99 Assault
0.549 0.450 0.000
X30-X39 Exposure to forces of nature
0.549 0.450 0.000
X00-X09 Exposure to smoke, fire and flames
0.549 0.450 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.549 0.450 0.000
W75-W84 Other accidental threats to breathing
0.549 0.450 0.000
W65-W74 Accidental drowning and submersion
0.549 0.450 0.000
V98-V99 Other and unspecified transport accidents
0.549 0.450 0.000
V95-V97 Air and space transport accidents
0.549 0.450 0.000
V90-V94 Water transport accidents
0.549 0.450 0.000
V70-V79 Bus occupant injured in transport accident
0.549 0.450 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.549 0.450 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.549 0.450 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.549 0.450 0.000
S92.1 Fracture of talus
0.549 0.451 0.000
S92.2 Fracture of other tarsal bone(s)
0.547 0.453 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.546 0.454 0.000
T36.0 Penicillins
0.545 0.455 0.000
T50.8 Diagnostic agents
0.545 0.455 0.000
T50.7 Analeptics and opioid receptor antagonists
0.545 0.455 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.545 0.455 0.000
T50.5 Appetite depressants
0.545 0.455 0.000
T50.4 Drugs affecting uric acid metabolism
0.545 0.455 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.545 0.455 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.545 0.455 0.000
T50.1 Loop [high-ceiling] diuretics
0.545 0.455 0.000
T50.0 Mineralocorticoids and their antagonists
0.545 0.455 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.545 0.455 0.000
S00.9 Superficial injury of head, part unspecified
0.544 0.455 0.000
V20-V29 Motorcycle rider injured in transport accident
0.544 0.456 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.542 0.458 0.000
T19 Foreign body in genito-urinary tract
0.542 0.458 0.000
T15 Foreign body on external eye
0.542 0.458 0.000
T16 Foreign body in ear
0.542 0.458 0.000
S05.9 Injury of eye and orbit, part unspecified
0.541 0.459 0.000
H35.9 Retinal disorder, unspecified
0.540 0.460 0.000
S05.7 Avulsion of eye
0.539 0.461 0.000
S05.6 Penetrating wound of eyeball without foreign body
0.539 0.461 0.000
S05.5 Penetrating wound of eyeball with foreign body
0.539 0.461 0.000
S05.4 Penetrating wound of orbit with or without foreign body
0.539 0.461 0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.539 0.461 0.000
T17.2 Foreign body in pharynx
0.539 0.461 0.000
S02.50 Fracture of tooth (closed)
0.538 0.462 0.000
V40-V49 Car occupant injured in transport accident
0.538 0.462 0.000
T59.9 Gases, fumes and vapours, unspecified
0.538 0.462 0.000
T59.7 Carbon dioxide
0.538 0.462 0.000
T59.6 Hydrogen sulphide
0.538 0.462 0.000
T59.5 Fluorine gas and hydrogen fluoride
0.538 0.462 0.000
T59.4 Chlorine gas
0.538 0.462 0.000
T59.3 Lachrymogenic gas
0.538 0.462 0.000
T59.2 Formaldehyde
0.538 0.462 0.000
T59.1 Sulphur dioxide
0.538 0.462 0.000
T59.0 Nitrogen oxides
0.538 0.462 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.536 0.464 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.535 0.465 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.535 0.465 0.000
T46.7 Peripheral vasodilators
0.535 0.465 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.535 0.465 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.535 0.465 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.535 0.465 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.535 0.465 0.000
H35.6 Retinal haemorrhage
0.535 0.465 0.000
K81.9 Cholecystitis, unspecified
0.534 0.466 0.000
Q53 Undescended testicle
0.534 0.466 0.000
X84 Intentional self-harm by unspecified means
0.534 0.466 0.000
X83 Intentional self-harm by other specified means
0.534 0.466 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.534 0.466 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.534 0.466 0.000
X80 Intentional self-harm by jumping from a high place
0.534 0.466 0.000
X79 Intentional self-harm by blunt object
0.534 0.466 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.534 0.466 0.000
X76 Intentional self-harm by smoke, fire and flames
0.534 0.466 0.000
X75 Intentional self-harm by explosive material
0.534 0.466 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.534 0.466 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.534 0.466 0.000
X72 Intentional self-harm by handgun discharge
0.534 0.466 0.000
X71 Intentional self-harm by drowning and submersion
0.534 0.466 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.534 0.466 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.534 0.466 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.534 0.466 0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.534 0.466 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.534 0.466 0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.534 0.466 0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.534 0.466 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.534 0.466 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.533 0.467 0.000
S02.31 Fracture of orbital floor (open)
0.532 0.467 0.000
S91.0 Open wound of ankle
0.532 0.468 0.000
Q52.5 Fusion of labia
0.531 0.469 0.000
S92.9 Fracture of foot, unspecified
0.531 0.469 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.531 0.469 0.000
H15 Disorders of sclera
0.531 0.469 0.000
S71 Open wound of hip and thigh
0.531 0.469 0.000
T06 Other injuries involving multiple body regions, not elsewhere classified
0.530 0.470 0.000
T05 Traumatic amputations involving multiple body regions
0.530 0.470 0.000
T04 Crushing injuries involving multiple body regions
0.530 0.470 0.000
T03 Dislocations, sprains and strains involving multiple body regions
0.530 0.470 0.000
T02 Fractures involving multiple body regions
0.530 0.470 0.000
T01 Open wounds involving multiple body regions
0.530 0.470 0.000
T07 Unspecified multiple injuries
0.530 0.470 0.000
Q66.6 Other congenital valgus deformities of feet
0.530 0.470 0.000
F25 Schizoaffective disorders
0.530 0.470 0.000
D80-D89 Certain disorders involving the immune mechanism
0.529 0.470 0.000
S02.20 Fracture of nasal bones (closed)
0.529 0.471 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.528 0.472 0.000
H35.1 Retinopathy of prematurity
0.528 0.472 0.000
S00.4 Superficial injury of ear
0.526 0.473 0.000
T36.9 Systemic antibiotic, unspecified
0.526 0.474 0.000
T36.8 Other systemic antibiotics
0.526 0.474 0.000
T36.7 Antifungal antibiotics, systemically used
0.526 0.474 0.000
T36.6 Rifamycins
0.526 0.474 0.000
T36.5 Aminoglycosides
0.526 0.474 0.000
T36.4 Tetracyclines
0.526 0.474 0.000
T36.3 Macrolides
0.526 0.474 0.000
T36.2 Chloramphenicol group
0.526 0.474 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.526 0.474 0.000
S41 Open wound of shoulder and upper arm
0.526 0.474 0.000
H47.2 Optic atrophy
0.526 0.474 0.000
Q82 Other congenital malformations of skin
0.525 0.475 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.525 0.475 0.000
S02.6 Fracture of mandible
0.525 0.475 0.000
S02.70 Multiple fractures involving skull and facial bones (closed)
0.522 0.478 0.000
W17 Other fall from one level to another
0.521 0.479 0.000
W07 Fall involving chair
0.520 0.480 0.000
Q78 Other osteochondrodysplasias
0.519 0.481 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.519 0.481 0.000
Q76 Congenital malformations of spine and bony thorax
0.519 0.481 0.000
Q75 Other congenital malformations of skull and face bones
0.519 0.481 0.000
Q74 Other congenital malformations of limb(s)
0.519 0.481 0.000
Q73 Reduction defects of unspecified limb
0.519 0.481 0.000
Q72 Reduction defects of lower limb
0.519 0.481 0.000
Q71 Reduction defects of upper limb
0.519 0.481 0.000
Q70 Syndactyly
0.519 0.481 0.000
Q69 Polydactyly
0.519 0.481 0.000
Q68 Other congenital musculoskeletal deformities
0.519 0.481 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.519 0.481 0.000
H21.9 Disorder of iris and ciliary body, unspecified
0.518 0.482 0.000
S88 Traumatic amputation of lower leg
0.518 0.482 0.000
S87 Crushing injury of lower leg
0.518 0.482 0.000
S85 Injury of blood vessels at lower leg level
0.518 0.482 0.000
S84 Injury of nerves at lower leg level
0.518 0.482 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.518 0.482 0.000
Q54.9 Hypospadias, unspecified
0.518 0.482 0.000
T56.8 Other metals
0.518 0.482 0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents
0.517 0.483 0.000
H35.2 Other proliferative retinopathy
0.516 0.484 0.000
V80-V89 Other land transport accidents
0.516 0.484 0.000
S00.1 Contusion of eyelid and periocular area
0.516 0.484 0.000
F60-F69 Disorders of adult personality and behaviour
0.516 0.484 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.516 0.484 0.000
Q66.8 Other congenital deformities of feet
0.516 0.484 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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