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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12475176
log Bayes Factor = 5.95848
Chromosome 2   position 65,205,008  (GRCh37) Explore rs12475176 on Ensembl!
Variant rs12475176 is part of Cluster X0079

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.997 0.003 0.000
Chapter II Neoplasms
0.997 0.003 0.000
E11 Non-insulin-dependent diabetes mellitus
0.994 0.006 0.000
Chapter X Diseases of the respiratory system
0.990 0.010 0.000
Chapter VII Diseases of the eye and adnexa
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.983 0.017 0.000
H53-H54 Visual disturbances and blindness
0.973 0.027 0.000
J95-J99 Other diseases of the respiratory system
0.972 0.028 0.000
Chapter XX External causes of morbidity and mortality
0.971 0.029 0.000
C64-C68 Malignant neoplasms of urinary tract
0.969 0.031 0.000
C15-C26 Malignant neoplasms of digestive organs
0.968 0.032 0.000
G40-G47 Episodic and paroxysmal disorders
0.967 0.033 0.000
E11.3 With ophthalmic complications
0.960 0.040 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.955 0.045 0.000
J98 Other respiratory disorders
0.954 0.046 0.000
H25-H28 Disorders of lens
0.951 0.049 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.950 0.050 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.946 0.054 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.946 0.054 0.000
S50-S59 Injuries to the elbow and forearm
0.941 0.059 0.000
C67 Malignant neoplasm of bladder
0.938 0.062 0.000
E14 Unspecified diabetes mellitus
0.938 0.062 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.935 0.065 0.000
H53 Visual disturbances
0.930 0.070 0.000
J84 Other interstitial pulmonary diseases
0.930 0.070 0.000
G47 Sleep disorders
0.929 0.071 0.000
Chapter VIII Diseases of the ear and mastoid process
0.927 0.073 0.000
E11.4 With neurological complications
0.924 0.076 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.918 0.082 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.917 0.083 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.916 0.084 0.000
W20-W49 Exposure to inanimate mechanical forces
0.914 0.086 0.000
E50-E64 Other nutritional deficiencies
0.909 0.091 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.907 0.093 0.000
H25 Senile cataract
0.907 0.093 0.000
E20-E35 Disorders of other endocrine glands
0.903 0.097 0.000
H54 Blindness and low vision
0.901 0.099 0.000
H53.8 Other visual disturbances
0.899 0.101 0.000
C67.9 Bladder, unspecified
0.895 0.105 0.000
G43 Migraine
0.895 0.105 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.894 0.106 0.000
H65-H75 Diseases of middle ear and mastoid
0.894 0.106 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.887 0.113 0.000
Y52 Agents primarily affecting the cardiovascular system
0.886 0.114 0.000
S51 Open wound of forearm
0.885 0.115 0.000
G90-G99 Other disorders of the nervous system
0.885 0.115 0.000
H25.9 Senile cataract, unspecified
0.883 0.117 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.882 0.118 0.000
C21 Malignant neoplasm of anus and anal canal
0.875 0.125 0.000
J60-J70 Lung diseases due to external agents
0.872 0.128 0.000
E14.9 Without complications
0.865 0.135 0.000
C15 Malignant neoplasm of oesophagus
0.864 0.136 0.000
S40-S49 Injuries to the shoulder and upper arm
0.858 0.142 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.856 0.144 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.848 0.152 0.000
E11.9 Without complications
0.848 0.152 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.844 0.156 0.000
G47.9 Sleep disorder, unspecified
0.841 0.159 0.000
H53.0 Amblyopia ex anopsia
0.840 0.160 0.000
S70-S79 Injuries to the hip and thigh
0.838 0.162 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.837 0.163 0.000
C17 Malignant neoplasm of small intestine
0.836 0.164 0.000
E11.2 With renal complications
0.834 0.166 0.000
E23 Hypofunction and other disorders of pituitary gland
0.832 0.168 0.000
J98.4 Other disorders of lung
0.831 0.169 0.000
H26 Other cataract
0.830 0.170 0.000
Q80-Q89 Other congenital malformations
0.826 0.174 0.000
G20-G26 Extrapyramidal and movement disorders
0.826 0.174 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.825 0.175 0.000
C71 Malignant neoplasm of brain
0.822 0.178 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.819 0.181 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.818 0.182 0.000
J98.1 Pulmonary collapse
0.818 0.182 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.817 0.183 0.000
H54.4 Blindness, one eye
0.816 0.184 0.000
H69 Other disorders of Eustachian tube
0.815 0.185 0.000
G43.9 Migraine, unspecified
0.815 0.185 0.000
H26.9 Cataract, unspecified
0.814 0.186 0.000
G41 Status epilepticus
0.813 0.187 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.813 0.187 0.000
S60-S69 Injuries to the wrist and hand
0.813 0.187 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.812 0.188 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.811 0.189 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.807 0.193 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.805 0.195 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.804 0.196 0.000
C67.2 Lateral wall of bladder
0.804 0.196 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.802 0.197 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.802 0.198 0.000
S56 Injury of muscle and tendon at forearm level
0.801 0.199 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.801 0.199 0.000
G47.3 Sleep apnoea
0.801 0.199 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.800 0.200 0.000
Y42.7 Androgens and anabolic congeners
0.799 0.201 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.797 0.203 0.000
E55 Vitamin D deficiency
0.794 0.206 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.790 0.210 0.000
C51-C58 Malignant neoplasms of female genital organs
0.790 0.210 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.789 0.211 0.000
C16 Malignant neoplasm of stomach
0.788 0.212 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.787 0.213 0.000
Chapter V Mental and behavioural disorders
0.785 0.215 0.000
S50 Superficial injury of forearm
0.785 0.215 0.000
J40-J47 Chronic lower respiratory diseases
0.784 0.216 0.000
C15.4 Middle third of oesophagus
0.783 0.217 0.000
G93 Other disorders of brain
0.783 0.217 0.000
E14.3 With ophthalmic complications
0.782 0.218 0.000
Chapter XXII Codes for special purposes
0.782 0.218 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.782 0.218 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.782 0.218 0.000
S51.0 Open wound of elbow
0.781 0.219 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.781 0.219 0.000
E65-E68 Obesity and other hyperalimentation
0.779 0.221 0.000
M86-M90 Other osteopathies
0.778 0.222 0.000
H25.1 Senile nuclear cataract
0.778 0.222 0.000
S80-S89 Injuries to the knee and lower leg
0.777 0.223 0.000
E13 Other specified diabetes mellitus
0.776 0.224 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.774 0.226 0.000
E11.5 With peripheral circulatory complications
0.774 0.226 0.000
S90-S99 Injuries to the ankle and foot
0.773 0.227 0.000
J98.8 Other specified respiratory disorders
0.772 0.228 0.000
T00-T07 Injuries involving multiple body regions
0.771 0.229 0.000
C25 Malignant neoplasm of pancreas
0.771 0.229 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.770 0.230 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.765 0.235 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.764 0.236 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.763 0.237 0.000
C69 Malignant neoplasm of eye and adnexa
0.762 0.238 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.761 0.239 0.000
T93 Sequelae of injuries of lower limb
0.760 0.240 0.000
W28 Contact with powered lawn mower
0.760 0.240 0.000
G25 Other extrapyramidal and movement disorders
0.759 0.241 0.000
X50-X57 Overexertion, travel and privation
0.758 0.242 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.755 0.244 0.000
V20-V29 Motorcycle rider injured in transport accident
0.755 0.245 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.754 0.246 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.753 0.247 0.000
H10-H13 Disorders of conjunctiva
0.752 0.247 0.000
E27 Other disorders of adrenal gland
0.752 0.248 0.000
S72 Fracture of femur
0.752 0.248 0.000
S60 Superficial injury of wrist and hand
0.751 0.249 0.000
W21 Striking against or struck by sports equipment
0.751 0.249 0.000
T79-T79 Certain early complications of trauma
0.751 0.249 0.000
E53 Deficiency of other B group vitamins
0.748 0.252 0.000
S42 Fracture of shoulder and upper arm
0.748 0.252 0.000
X60-X84 Intentional self-harm
0.747 0.253 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.747 0.253 0.000
J30-J39 Other diseases of upper respiratory tract
0.747 0.253 0.000
H90-H95 Other disorders of ear
0.746 0.254 0.000
G43.8 Other migraine
0.744 0.256 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.743 0.257 0.000
C67.5 Bladder neck
0.743 0.257 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.742 0.258 0.000
C21.1 Anal canal
0.740 0.260 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.738 0.261 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.738 0.262 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.738 0.262 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.738 0.262 0.000
H65 Nonsuppurative otitis media
0.736 0.264 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.736 0.264 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.736 0.264 0.000
S51.8 Open wound of other parts of forearm
0.735 0.265 0.000
D37.4 Colon
0.735 0.265 0.000
H66 Suppurative and unspecified otitis media
0.733 0.266 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.733 0.267 0.000
M40-M43 Deforming dorsopathies
0.733 0.267 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.733 0.267 0.000
H72 Perforation of tympanic membrane
0.733 0.267 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.732 0.268 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.732 0.268 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.731 0.269 0.000
E11.1 With ketoacidosis
0.730 0.270 0.000
H54.6 Unqualified visual loss, one eye
0.729 0.271 0.000
H54.7 Unspecified visual loss
0.729 0.271 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.728 0.272 0.000
G96 Other disorders of central nervous system
0.728 0.272 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.727 0.273 0.000
M20-M25 Other joint disorders
0.727 0.273 0.000
W50-W64 Exposure to animate mechanical forces
0.727 0.273 0.000
S20-S29 Injuries to the thorax
0.725 0.275 0.000
M86 Osteomyelitis
0.724 0.276 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.724 0.276 0.000
J84.8 Other specified interstitial pulmonary diseases
0.724 0.276 0.000
W25 Contact with sharp glass
0.722 0.278 0.000
J80 Adult respiratory distress syndrome
0.722 0.278 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.721 0.279 0.000
T85.2 Mechanical complication of intraocular lens
0.719 0.281 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.719 0.281 0.000
H69.8 Other specified disorders of Eustachian tube
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.715 0.285 0.000
D39.1 Ovary
0.715 0.285 0.000
E12 Malnutrition-related diabetes mellitus
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
E22 Hyperfunction of pituitary gland
0.713 0.287 0.000
Q85 Phakomatoses, not elsewhere classified
0.713 0.287 0.000
C23 Malignant neoplasm of gallbladder
0.713 0.287 0.000
E11.7 With multiple complications
0.713 0.287 0.000
E11.0 With coma
0.713 0.287 0.000
G95 Other diseases of spinal cord
0.712 0.288 0.000
E55.9 Vitamin D deficiency, unspecified
0.712 0.288 0.000
H93 Other disorders of ear, not elsewhere classified
0.708 0.292 0.000
Y42.5 Other oestrogens and progestogens
0.708 0.292 0.000
W22 Striking against or struck by other objects
0.708 0.292 0.000
M25 Other joint disorders, not elsewhere classified
0.707 0.293 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.706 0.293 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.706 0.294 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.706 0.294 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.705 0.295 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.705 0.295 0.000
G41.9 Status epilepticus, unspecified
0.703 0.297 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.703 0.297 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.702 0.298 0.000
H53.4 Visual field defects
0.701 0.299 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.700 0.300 0.000
C67.1 Dome of bladder
0.700 0.300 0.000
H74 Other disorders of middle ear and mastoid
0.699 0.301 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.699 0.301 0.000
J96 Respiratory failure, not elsewhere classified
0.697 0.303 0.000
H55-H59 Other disorders of eye and adnexa
0.697 0.303 0.000
D46 Myelodysplastic syndromes
0.697 0.303 0.000
Y35-Y36 Legal intervention and operations of war
0.696 0.304 0.000
Y10-Y34 Event of undetermined intent
0.696 0.304 0.000
X85-X99 Assault
0.696 0.304 0.000
X30-X39 Exposure to forces of nature
0.696 0.304 0.000
X00-X09 Exposure to smoke, fire and flames
0.696 0.304 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.696 0.304 0.000
W75-W84 Other accidental threats to breathing
0.696 0.304 0.000
W65-W74 Accidental drowning and submersion
0.696 0.304 0.000
V98-V99 Other and unspecified transport accidents
0.696 0.304 0.000
V95-V97 Air and space transport accidents
0.696 0.304 0.000
V90-V94 Water transport accidents
0.696 0.304 0.000
V70-V79 Bus occupant injured in transport accident
0.696 0.304 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.696 0.304 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.696 0.304 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.696 0.304 0.000
V01-V09 Pedestrian injured in transport accident
0.696 0.304 0.000
E23.0 Hypopituitarism
0.695 0.305 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.694 0.305 0.000
C65 Malignant neoplasm of renal pelvis
0.694 0.305 0.000
E11.8 With unspecified complications
0.694 0.306 0.000
J95.8 Other postprocedural respiratory disorders
0.693 0.306 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.693 0.306 0.000
C56 Malignant neoplasm of ovary
0.693 0.307 0.000
G90 Disorders of autonomic nervous system
0.693 0.307 0.000
S51.9 Open wound of forearm, part unspecified
0.693 0.307 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.692 0.308 0.000
Y52.1 Calcium-channel blockers
0.692 0.308 0.000
C17.0 Duodenum
0.691 0.309 0.000
E11.6 With other specified complications
0.689 0.311 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.689 0.311 0.000
J98.9 Respiratory disorder, unspecified
0.689 0.311 0.000
E23.2 Diabetes insipidus
0.688 0.312 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.687 0.313 0.000
E23.6 Other disorders of pituitary gland
0.687 0.313 0.000
E26 Hyperaldosteronism
0.687 0.313 0.000
C71.0 Cerebrum, except lobes and ventricles
0.686 0.314 0.000
T14 Injury of unspecified body region
0.686 0.314 0.000
W29 Contact with other powered hand tools and household machinery
0.685 0.314 0.000
J98.6 Disorders of diaphragm
0.684 0.316 0.000
J98.3 Compensatory emphysema
0.684 0.316 0.000
J98.2 Interstitial emphysema
0.684 0.316 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.684 0.316 0.000
C67.0 Trigone of bladder
0.684 0.316 0.000
Y00-Y09 Assault
0.683 0.316 0.000
W44 Foreign body entering into or through eye or natural orifice
0.683 0.317 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.682 0.318 0.000
H69.9 Eustachian tube disorder, unspecified
0.682 0.318 0.000
X20-X29 Contact with venomous animals and plants
0.682 0.318 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.682 0.318 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.682 0.318 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.681 0.319 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.681 0.319 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.680 0.320 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.679 0.321 0.000
E61 Deficiency of other nutrient elements
0.679 0.321 0.000
Y41.0 Sulphonamides
0.679 0.321 0.000
S72.2 Subtrochanteric fracture
0.678 0.322 0.000
Y59 Other and unspecified vaccines and biological substances
0.678 0.322 0.000
Y58 Bacterial vaccines
0.678 0.322 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.678 0.322 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.678 0.322 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.678 0.322 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.678 0.322 0.000
Y48 Anaesthetics and therapeutic gases
0.678 0.322 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.678 0.322 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.678 0.322 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.678 0.322 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.678 0.322 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.678 0.322 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.678 0.322 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.678 0.322 0.000
E34 Other endocrine disorders
0.678 0.322 0.000
G93.4 Encephalopathy, unspecified
0.677 0.322 0.000
Q00-Q07 Congenital malformations of the nervous system
0.677 0.323 0.000
G47.8 Other sleep disorders
0.677 0.323 0.000
G25.3 Myoclonus
0.676 0.324 0.000
H46 Optic neuritis
0.676 0.324 0.000
S51.7 Multiple open wounds of forearm
0.676 0.324 0.000
G91 Hydrocephalus
0.675 0.325 0.000
C71.9 Brain, unspecified
0.675 0.325 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.675 0.325 0.000
S59 Other and unspecified injuries of forearm
0.674 0.325 0.000
S58 Traumatic amputation of forearm
0.674 0.325 0.000
S57 Crushing injury of forearm
0.674 0.325 0.000
S55 Injury of blood vessels at forearm level
0.674 0.325 0.000
S54 Injury of nerves at forearm level
0.674 0.325 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.674 0.325 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.674 0.326 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.674 0.326 0.000
C67.8 Overlapping lesion of bladder
0.673 0.327 0.000
C67.7 Urachus
0.673 0.327 0.000
C67.3 Anterior wall of bladder
0.673 0.327 0.000
E14.8 With unspecified complications
0.672 0.328 0.000
E14.7 With multiple complications
0.672 0.328 0.000
E14.6 With other specified complications
0.672 0.328 0.000
E14.5 With peripheral circulatory complications
0.672 0.328 0.000
E14.4 With neurological complications
0.672 0.328 0.000
E14.2 Withrenal complications
0.672 0.328 0.000
E14.1 With ketoacidosis
0.672 0.328 0.000
E14.0 With coma
0.672 0.328 0.000
H93.1 Tinnitus
0.672 0.328 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.672 0.328 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.671 0.329 0.000
C71.4 Occipital lobe
0.671 0.329 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.670 0.329 0.000
Q35-Q37 Cleft lip and cleft palate
0.670 0.330 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.670 0.330 0.000
M25.4 Effusion of joint
0.670 0.330 0.000
T23 Burn and corrosion of wrist and hand
0.669 0.331 0.000
G24 Dystonia
0.669 0.331 0.000
V40-V49 Car occupant injured in transport accident
0.668 0.332 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.668 0.332 0.000
T66-T78 Other and unspecified effects of external causes
0.667 0.333 0.000
S63.6 Sprain and strain of finger(s)
0.667 0.333 0.000
C17.9 Small intestine, unspecified
0.667 0.333 0.000
H53.6 Night blindness
0.667 0.333 0.000
H53.5 Colour vision deficiencies
0.667 0.333 0.000
H53.3 Other disorders of binocular vision
0.667 0.333 0.000
J84.0 Alveolar and parietoalveolar conditions
0.667 0.333 0.000
G47.4 Narcolepsy and cataplexy
0.666 0.334 0.000
G47.2 Disorders of the sleep-wake schedule
0.666 0.334 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.665 0.335 0.000
T87 Complications peculiar to reattachment and amputation
0.664 0.335 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.664 0.336 0.000
C15.3 Upper third of oesophagus
0.663 0.337 0.000
W20 Struck by thrown, projected or falling object
0.662 0.337 0.000
G25.0 Essential tremor
0.662 0.338 0.000
T21 Burn and corrosion of trunk
0.662 0.338 0.000
Q65 Congenital deformities of hip
0.661 0.339 0.000
C88 Malignant immunoproliferative diseases
0.661 0.339 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.661 0.339 0.000
E27.8 Other specified disorders of adrenal gland
0.660 0.340 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.660 0.340 0.000
J81 Pulmonary oedema
0.659 0.341 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.659 0.341 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.658 0.341 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.658 0.341 0.000
C21.0 Anus, unspecified
0.658 0.342 0.000
E40-E46 Malnutrition
0.658 0.342 0.000
M25.5 Pain in joint
0.658 0.342 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.658 0.342 0.000
C70 Malignant neoplasm of meninges
0.658 0.342 0.000
V10-V19 Pedal cyclist injured in transport accident
0.657 0.343 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.656 0.343 0.000
F80-F89 Disorders of psychological development
0.656 0.344 0.000
W46 Contact with hypodermic needle
0.655 0.344 0.000
W45 Foreign body or object entering through skin
0.655 0.344 0.000
W43 Exposure to vibration
0.655 0.344 0.000
W42 Exposure to noise
0.655 0.344 0.000
W41 Exposure to high-pressure jet
0.655 0.344 0.000
W40 Explosion of other materials
0.655 0.344 0.000
W39 Discharge of firework
0.655 0.344 0.000
W38 Explosion and rupture of other specified pressurised devices
0.655 0.344 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.655 0.344 0.000
W36 Explosion and rupture of gas cylinder
0.655 0.344 0.000
W35 Explosion and rupture of boiler
0.655 0.344 0.000
W34 Discharge from other and unspecified firearms
0.655 0.344 0.000
W33 Rifle, shotgun and larger firearm discharge
0.655 0.344 0.000
W32 Handgun discharge
0.655 0.344 0.000
W31 Contact with other and unspecified machinery
0.655 0.344 0.000
W30 Contact with agricultural machinery
0.655 0.344 0.000
W27 Contact with nonpowered hand tool
0.655 0.344 0.000
W26 Contact with knife, sword or dagger
0.655 0.344 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.655 0.344 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.655 0.344 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.655 0.345 0.000
Q89 Other congenital malformations, not elsewhere classified
0.655 0.345 0.000
M25.56 Pain in joint (Lower leg)
0.654 0.346 0.000
J43 Emphysema
0.653 0.347 0.000
M00-M03 Infectious arthropathies
0.653 0.347 0.000
S42.2 Fracture of upper end of humerus
0.653 0.347 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.653 0.347 0.000
M86.9 Osteomyelitis, unspecified
0.652 0.348 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.652 0.348 0.000
E63 Other nutritional deficiencies
0.652 0.348 0.000
E56 Other vitamin deficiencies
0.652 0.348 0.000
E51 Thiamine deficiency
0.652 0.348 0.000
E50 Vitamin A deficiency
0.652 0.348 0.000
E60 Dietary zinc deficiency
0.652 0.348 0.000
E59 Dietary selenium deficiency
0.652 0.348 0.000
E58 Dietary calcium deficiency
0.652 0.348 0.000
E54 Ascorbic acid deficiency
0.652 0.348 0.000
E52 Niacin deficiency [pellagra]
0.652 0.348 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.652 0.348 0.000
S89 Other and unspecified injuries of lower leg
0.651 0.349 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.651 0.349 0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level
0.650 0.350 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.650 0.350 0.000
C95 Leukaemia of unspecified cell type
0.650 0.350 0.000
C94 Other leukaemias of specified cell type
0.650 0.350 0.000
C93 Monocytic leukaemia
0.650 0.350 0.000
C86 Other specified types of T/NK-cell lymphoma
0.650 0.350 0.000
H25.2 Senile cataract, morgagnian type
0.650 0.350 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.650 0.350 0.000
C67.4 Posterior wall of bladder
0.650 0.350 0.000
M60-M63 Disorders of muscles
0.650 0.350 0.000
W28.9 Unspecified place
0.649 0.351 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.648 0.352 0.000
E32 Diseases of thymus
0.648 0.352 0.000
E31 Polyglandular dysfunction
0.648 0.352 0.000
E30 Disorders of puberty, not elsewhere classified
0.648 0.352 0.000
E25 Adrenogenital disorders
0.648 0.352 0.000
E24 Cushing's syndrome
0.648 0.352 0.000
E20 Hypoparathyroidism
0.648 0.352 0.000
X59 Exposure to unspecified factor
0.646 0.354 0.000
H54.5 Low vision, one eye
0.646 0.354 0.000
H54.3 Unqualified visual loss, both eyes
0.646 0.354 0.000
H54.2 Low vision, both eyes
0.646 0.354 0.000
H54.1 Blindness, one eye, low vision, other eye
0.646 0.354 0.000
G70-G73 Diseases of myoneural junction and muscle
0.645 0.354 0.000
S50.0 Contusion of elbow
0.645 0.355 0.000
S60.8 Other superficial injuries of wrist and hand
0.644 0.356 0.000
Q18 Other congenital malformations of face and neck
0.644 0.356 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.644 0.356 0.000
H72.8 Other perforations of tympanic membrane
0.644 0.356 0.000
C16.0 Cardia
0.643 0.357 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.642 0.358 0.000
G43.3 Complicated migraine
0.641 0.358 0.000
G43.2 Status migrainosus
0.641 0.358 0.000
G43.0 Migraine without aura [common migraine]
0.641 0.358 0.000
Y40 Systemic antibiotics
0.641 0.358 0.000
H11 Other disorders of conjunctiva
0.641 0.359 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.641 0.359 0.000
H70 Mastoiditis and related conditions
0.641 0.359 0.000
H68 Eustachian salpingitis and obstruction
0.641 0.359 0.000
H67 Otitis media in diseases classified elsewhere
0.641 0.359 0.000
H47.3 Other disorders of optic disk
0.640 0.360 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.640 0.360 0.000
M25.46 Effusion of joint (Lower leg)
0.639 0.361 0.000
G93.0 Cerebral cysts
0.639 0.361 0.000
H54.9 Unspecified visual impairment (binocular)
0.638 0.362 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.637 0.363 0.000
M41 Scoliosis
0.636 0.364 0.000
Y42.9 Other and unspecified hormone antagonists
0.636 0.364 0.000
Y42.4 Oral contraceptives
0.636 0.364 0.000
Y42.2 Antithyroid drugs
0.636 0.364 0.000
Y42.1 Thyroid hormones and substitutes
0.636 0.364 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.636 0.364 0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level
0.636 0.364 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.636 0.364 0.000
C66 Malignant neoplasm of ureter
0.636 0.364 0.000
V80-V89 Other land transport accidents
0.635 0.365 0.000
J38.0 Paralysis of vocal cords and larynx
0.635 0.365 0.000
D37.9 Digestive organ, unspecified
0.635 0.365 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.635 0.365 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.635 0.365 0.000
Y52.7 Peripheral vasodilators
0.635 0.365 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.635 0.365 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.635 0.365 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.635 0.365 0.000
Q50-Q56 Congenital malformations of genital organs
0.634 0.365 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.634 0.365 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.634 0.365 0.000
G92 Toxic encephalopathy
0.634 0.365 0.000
W21.9 Unspecified place
0.633 0.366 0.000
F22 Persistent delusional disorders
0.633 0.366 0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents
0.633 0.367 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.633 0.367 0.000
E53.8 Deficiency of other specified B group vitamins
0.633 0.367 0.000
X58 Exposure to other specified factors
0.633 0.367 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.633 0.367 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.632 0.368 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.632 0.368 0.000
C69.3 Choroid
0.630 0.370 0.000
D43.2 Brain, unspecified
0.630 0.370 0.000
T92 Sequelae of injuries of upper limb
0.629 0.371 0.000
T98 Sequelae of other and unspecified effects of external causes
0.629 0.371 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.628 0.372 0.000
C21.2 Cloacogenic zone
0.628 0.372 0.000
E70-E90 Metabolic disorders
0.627 0.373 0.000
M89 Other disorders of bone
0.626 0.374 0.000
S72.20 Subtrochanteric fracture (closed)
0.626 0.374 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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