TreeWAS – Variant ID: rs1250307

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R10 Abdominal and pelvic pain	0.024	0.976	0.000
C15-C26 Malignant neoplasms of digestive organs	0.000	0.977	0.023
Chapter VI Diseases of the nervous system	0.023	0.977	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.023	0.977	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.977	0.022
R10.3 Pain localised to other parts of lower abdomen	0.023	0.977	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.022	0.978	0.000
C20 Malignant neoplasm of rectum	0.000	0.978	0.022
Chapter IX Diseases of the circulatory system	0.022	0.978	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.022	0.978	0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.022	0.978	0.000
# Top node	0.022	0.978	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.978	0.022
C25 Malignant neoplasm of pancreas	0.000	0.978	0.022
Chapter II Neoplasms	0.001	0.979	0.020
I84 Haemorrhoids	0.021	0.979	0.000
R10.1 Pain localised to upper abdomen	0.021	0.979	0.000
I84.9 Unspecified haemorrhoids without complication	0.021	0.979	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.979	0.021
R10.4 Other and unspecified abdominal pain	0.020	0.980	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.020	0.980	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.020	0.980	0.000
R42 Dizziness and giddiness	0.020	0.980	0.000
G40-G47 Episodic and paroxysmal disorders	0.020	0.980	0.000
I60-I69 Cerebrovascular diseases	0.020	0.980	0.000
C25.9 Pancreas, unspecified	0.000	0.981	0.019
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.981	0.019
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.019	0.981	0.000
M80-M85 Disorders of bone density and structure	0.019	0.981	0.000
Chapter V Mental and behavioural disorders	0.019	0.981	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.019	0.981	0.000
R11 Nausea and vomiting	0.019	0.981	0.000
M70-M79 Other soft tissue disorders	0.019	0.981	0.000
I85 Oesophageal varices	0.018	0.981	0.000
G30-G32 Other degenerative diseases of the nervous system	0.018	0.981	0.000
C78.7 Secondary malignant neoplasm of liver	0.000	0.981	0.018
Chapter VIII Diseases of the ear and mastoid process	0.018	0.981	0.000
R10.2 Pelvic and perineal pain	0.018	0.982	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.018	0.982	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.982	0.018
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.982	0.018
C51-C58 Malignant neoplasms of female genital organs	0.001	0.982	0.018
R47-R49 Symptoms and signs involving speech and voice	0.018	0.982	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.018	0.982	0.000
R10.0 Acute abdomen	0.018	0.982	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.018	0.982	0.000
I30-I52 Other forms of heart disease	0.018	0.982	0.000
Chapter XI Diseases of the digestive system	0.018	0.982	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.018	0.982	0.000
G20-G26 Extrapyramidal and movement disorders	0.018	0.982	0.000
S60-S69 Injuries to the wrist and hand	0.018	0.982	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.018	0.982	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.018	0.982	0.000
C16 Malignant neoplasm of stomach	0.000	0.982	0.018
R44 Other symptoms and signs involving general sensations and perceptions	0.018	0.982	0.000
Chapter I Certain infectious and parasitic diseases	0.018	0.982	0.000
M81 Osteoporosis without pathological fracture	0.018	0.982	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.982	0.018
C15 Malignant neoplasm of oesophagus	0.000	0.982	0.017
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.001	0.982	0.017
C23 Malignant neoplasm of gallbladder	0.000	0.982	0.017
R07 Pain in throat and chest	0.018	0.982	0.000
Chapter XIV Diseases of the genitourinary system	0.018	0.982	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.017	0.982	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.017	0.982	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.017	0.983	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.017	0.983	0.000
C21 Malignant neoplasm of anus and anal canal	0.000	0.983	0.017
G47 Sleep disorders	0.017	0.983	0.000
I84.2 Internal haemorrhoids without complication	0.017	0.983	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.983	0.017
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.001	0.983	0.016
C25.1 Body of pancreas	0.000	0.983	0.017
R12 Heartburn	0.017	0.983	0.000
R45 Symptoms and signs involving emotional state	0.017	0.983	0.000
N30-N39 Other diseases of urinary system	0.017	0.983	0.000
K90-K93 Other diseases of the digestive system	0.017	0.983	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.017	0.983	0.000
M81.9 Osteoporosis, unspecified	0.017	0.983	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.017	0.983	0.000
I87 Other disorders of veins	0.017	0.983	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.017	0.983	0.000
C17 Malignant neoplasm of small intestine	0.000	0.983	0.017
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.017	0.983	0.000
D00-D09 In situ neoplasms	0.001	0.983	0.016
C25.0 Head of pancreas	0.000	0.983	0.017
F00-F09 Organic, including symptomatic, mental disorders	0.017	0.983	0.000
M75 Shoulder lesions	0.017	0.983	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.017	0.983	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.983	0.017
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.017	0.983	0.000
C80 Malignant neoplasm without specification of site	0.000	0.983	0.017
R46 Symptoms and signs involving appearance and behaviour	0.017	0.983	0.000
I82 Other venous embolism and thrombosis	0.017	0.983	0.000
I84.5 External haemorrhoids without complication	0.017	0.983	0.000
N32 Other disorders of bladder	0.017	0.983	0.000
N10-N16 Renal tubulo-interstitial diseases	0.017	0.983	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.983	0.017
C18 Malignant neoplasm of colon	0.000	0.983	0.017
R17 Unspecified jaundice	0.017	0.983	0.000
R40 Somnolence, stupor and coma	0.017	0.983	0.000
G90-G99 Other disorders of the nervous system	0.017	0.983	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.001	0.983	0.016
G40 Epilepsy	0.017	0.983	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.017	0.983	0.000
C25.2 Tail of pancreas	0.000	0.983	0.016
I64 Stroke, not specified as haemorrhage or infarction	0.017	0.983	0.000
I88 Nonspecific lymphadenitis	0.017	0.983	0.000
I81 Portal vein thrombosis	0.017	0.983	0.000
R06 Abnormalities of breathing	0.017	0.983	0.000
R21 Rash and other nonspecific skin eruption	0.017	0.983	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.017	0.983	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.016	0.983	0.000
G44 Other headache syndromes	0.016	0.983	0.000
I69 Sequelae of cerebrovascular disease	0.016	0.983	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.984	0.016
I86 Varicose veins of other sites	0.016	0.984	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.984	0.016
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.984	0.016
R07.2 Precordial pain	0.016	0.984	0.000
Chapter XXII Codes for special purposes	0.016	0.984	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.016	0.984	0.000
C25.7 Other parts of pancreas	0.000	0.984	0.016
R01 Cardiac murmurs and other cardiac sounds	0.016	0.984	0.000
K70-K77 Diseases of liver	0.016	0.984	0.000
M40-M43 Deforming dorsopathies	0.016	0.984	0.000
I00-I02 Acute rheumatic fever	0.016	0.984	0.000
R19 Other symptoms and signs involving the digestive system and abdomen	0.016	0.984	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.984	0.016
M23 Internal derangement of knee	0.016	0.984	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.016	0.984	0.000
G70-G73 Diseases of myoneural junction and muscle	0.016	0.984	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.016	0.984	0.000
I84.6 Residual haemorrhoidal skin tags	0.016	0.984	0.000
B95-B98 Bacterial, viral and other infectious agents	0.016	0.984	0.000
I60 Subarachnoid haemorrhage	0.016	0.984	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.001	0.984	0.015
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.016	0.984	0.000
I84.4 External haemorrhoids with other complications	0.016	0.984	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.001	0.984	0.015
S40-S49 Injuries to the shoulder and upper arm	0.016	0.984	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.016	0.984	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.984	0.016
K92 Other diseases of digestive system	0.016	0.984	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.984	0.016
I84.3 External thrombosed haemorrhoids	0.016	0.984	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.016	0.984	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.984	0.016
T15-T19 Effects of foreign body entering through natural orifice	0.016	0.984	0.000
I61 Intracerebral haemorrhage	0.016	0.984	0.000
C25.8 Overlapping lesion of pancreas	0.000	0.984	0.016
C25.4 Endocrine pancreas	0.000	0.984	0.016
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.984	0.016
I70-I79 Diseases of arteries, arterioles and capillaries	0.016	0.984	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.984	0.016
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.016	0.984	0.000
R04 Haemorrhage from respiratory passages	0.016	0.984	0.000
C25.3 Pancreatic duct	0.000	0.984	0.015
R43 Disturbances of smell and taste	0.016	0.984	0.000
M20-M25 Other joint disorders	0.016	0.984	0.000
N32.8 Other specified disorders of bladder	0.016	0.984	0.000
G62 Other polyneuropathies	0.015	0.984	0.000
I85.9 Oesophageal varices without bleeding	0.015	0.984	0.000
H65-H75 Diseases of middle ear and mastoid	0.015	0.984	0.000
I51 Complications and ill-defined descriptions of heart disease	0.015	0.984	0.000
N35 Urethral stricture	0.015	0.985	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.985	0.015
S90-S99 Injuries to the ankle and foot	0.015	0.985	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.015	0.985	0.000
M80 Osteoporosis with pathological fracture	0.015	0.985	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.015	0.985	0.000
R47 Speech disturbances, not elsewhere classified	0.015	0.985	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.985	0.015
R18 Ascites	0.015	0.985	0.000
I44 Atrioventricular and left bundle-branch block	0.015	0.985	0.000
R02 Gangrene, not elsewhere classified	0.015	0.985	0.000
R15 Faecal incontinence	0.015	0.985	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.001	0.985	0.014
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.985	0.015
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.015	0.985	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.985	0.015
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.015	0.985	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.015	0.985	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.985	0.015
T20-T25 Burns and corrosions of external body surface, specified by site	0.015	0.985	0.000
G35 Multiple sclerosis	0.015	0.985	0.000
G43 Migraine	0.015	0.985	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.015	0.985	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.985	0.015
I80 Phlebitis and thrombophlebitis	0.015	0.985	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.015	0.985	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.015	0.985	0.000
S64 Injury of nerves at wrist and hand level	0.015	0.985	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.985	0.015
S50-S59 Injuries to the elbow and forearm	0.015	0.985	0.000
M86-M90 Other osteopathies	0.015	0.985	0.000
M75.4 Impingement syndrome of shoulder	0.015	0.985	0.000
C56 Malignant neoplasm of ovary	0.000	0.985	0.014
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.001	0.985	0.014
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.015	0.985	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.985	0.015
N13 Obstructive and reflux uropathy	0.015	0.985	0.000
D50-D53 Nutritional anaemias	0.015	0.985	0.000
G58 Other mononeuropathies	0.015	0.985	0.000
I83 Varicose veins of lower extremities	0.015	0.985	0.000
G61 Inflammatory polyneuropathy	0.015	0.985	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.015	0.985	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.985	0.015
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.015	0.985	0.000
K65-K67 Diseases of peritoneum	0.015	0.985	0.000
I31 Other diseases of pericardium	0.015	0.985	0.000
I05-I09 Chronic rheumatic heart diseases	0.015	0.985	0.000
F30-F39 Mood [affective] disorders	0.015	0.985	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.015	0.985	0.000
M05-M14 Inflammatory polyarthropathies	0.015	0.985	0.000
I84.0 Internal thrombosed haemorrhoids	0.014	0.985	0.000
K76 Other diseases of liver	0.015	0.985	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.014	0.985	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.014	0.985	0.000
R07.3 Other chest pain	0.015	0.985	0.000
M65-M68 Disorders of synovium and tendon	0.014	0.985	0.000
G30 Alzheimer's disease	0.014	0.985	0.000
C64-C68 Malignant neoplasms of urinary tract	0.001	0.985	0.014
G63 Polyneuropathy in diseases classified elsewhere	0.014	0.985	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.014	0.985	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.001	0.985	0.013
R16.1 Splenomegaly, not elsewhere classified	0.014	0.986	0.000
G41 Status epilepticus	0.014	0.986	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.014	0.986	0.000
M60-M63 Disorders of muscles	0.014	0.986	0.000
M84 Disorders of continuity of bone	0.014	0.986	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.014	0.986	0.000
C15.9 Oesophagus, unspecified	0.000	0.986	0.014
C77.2 Intra-abdominal lymph nodes	0.000	0.986	0.014
K92.1 Melaena	0.014	0.986	0.000
R41.3 Other amnesia	0.014	0.986	0.000
C91 Lymphoid leukaemia	0.001	0.986	0.014
I35 Nonrheumatic aortic valve disorders	0.014	0.986	0.000
I62 Other nontraumatic intracranial haemorrhage	0.014	0.986	0.000
M75.1 Rotator cuff syndrome	0.014	0.986	0.000
M00-M03 Infectious arthropathies	0.014	0.986	0.000
C60-C63 Malignant neoplasms of male genital organs	0.001	0.986	0.014
C16.5 Lesser curvature of stomach, unspecified	0.000	0.986	0.014
G47.3 Sleep apnoea	0.014	0.986	0.000
I47 Paroxysmal tachycardia	0.014	0.986	0.000
M91-M94 Chondropathies	0.014	0.986	0.000
N35.9 Urethral stricture, unspecified	0.014	0.986	0.000
C45 Mesothelioma	0.001	0.986	0.014
R25 Abnormal involuntary movements	0.014	0.986	0.000
M23.3 Other meniscus derangements	0.014	0.986	0.000
N32.9 Bladder disorder, unspecified	0.014	0.986	0.000
R09.1 Pleurisy	0.014	0.986	0.000
G24 Dystonia	0.014	0.986	0.000
I63 Cerebral infarction	0.014	0.986	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.014	0.986	0.000
T33-T35 Frostbite	0.014	0.986	0.000
T79-T79 Certain early complications of trauma	0.014	0.986	0.000
K92.2 Gastro-intestinal haemorrhage, unspecified	0.014	0.986	0.000
M83 Adult osteomalacia	0.014	0.986	0.000
F70-F79 Mental retardation	0.014	0.986	0.000
S70-S79 Injuries to the hip and thigh	0.014	0.986	0.000
R44.3 Hallucinations, unspecified	0.014	0.986	0.000
M82 Osteoporosis in diseases classified elsewhere	0.014	0.986	0.000
I85.0 Oesophageal varices with bleeding	0.014	0.986	0.000
M85 Other disorders of bone density and structure	0.014	0.986	0.000
F80-F89 Disorders of psychological development	0.014	0.986	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.014	0.986	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.001	0.986	0.013
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.014	0.986	0.000
N99-N99 Other disorders of the genitourinary system	0.014	0.986	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.014	0.986	0.000
C77.8 Lymph nodes of multiple regions	0.000	0.986	0.014
F60-F69 Disorders of adult personality and behaviour	0.014	0.986	0.000
N00-N08 Glomerular diseases	0.014	0.986	0.000
R44.1 Visual hallucinations	0.014	0.986	0.000
G20 Parkinson's disease	0.014	0.986	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.014	0.986	0.000
C77.9 Lymph node, unspecified	0.000	0.986	0.014
D06 Carcinoma in situ of cervix uteri	0.001	0.986	0.013
S10-S19 Injuries to the neck	0.014	0.986	0.000
R01.1 Cardiac murmur, unspecified	0.014	0.986	0.000
R06.5 Mouth breathing	0.014	0.986	0.000
S62 Fracture at wrist and hand level	0.014	0.986	0.000
H60-H62 Diseases of external ear	0.014	0.986	0.000
G64 Other disorders of peripheral nervous system	0.014	0.986	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.014	0.986	0.000
I95 Hypotension	0.014	0.986	0.000
N32.0 Bladder-neck obstruction	0.014	0.986	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.014	0.986	0.000
T00-T07 Injuries involving multiple body regions	0.014	0.986	0.000
G40.9 Epilepsy, unspecified	0.014	0.986	0.000
D04 Carcinoma in situ of skin	0.001	0.986	0.013
S67 Crushing injury of wrist and hand	0.014	0.986	0.000
H90-H95 Other disorders of ear	0.014	0.986	0.000
G56 Mononeuropathies of upper limb	0.014	0.986	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.014	0.986	0.000
M76 Enthesopathies of lower limb, excluding foot	0.014	0.986	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.001	0.986	0.013
C54 Malignant neoplasm of corpus uteri	0.001	0.986	0.013
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.001	0.986	0.012
K35-K38 Diseases of appendix	0.014	0.986	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.014	0.986	0.000
G47.9 Sleep disorder, unspecified	0.014	0.986	0.000
I89.0 Lymphoedema, not elsewhere classified	0.014	0.986	0.000
I46 Cardiac arrest	0.014	0.986	0.000
S68 Traumatic amputation of wrist and hand	0.014	0.986	0.000
C21.0 Anus, unspecified	0.000	0.986	0.013
I89.1 Lymphangitis	0.013	0.986	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.014	0.986	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.013	0.986	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.013	0.986	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.013	0.986	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.014	0.986	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.014	0.986	0.000
C53 Malignant neoplasm of cervix uteri	0.001	0.986	0.013
S65 Injury of blood vessels at wrist and hand level	0.014	0.986	0.000
F99-F99 Unspecified mental disorder	0.013	0.986	0.000
C52 Malignant neoplasm of vagina	0.001	0.986	0.013
F17 Mental and behavioural disorders due to use of tobacco	0.014	0.986	0.000
S61 Open wound of wrist and hand	0.014	0.986	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.001	0.986	0.013
S69 Other and unspecified injuries of wrist and hand	0.013	0.986	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.013	0.986	0.000
C51 Malignant neoplasm of vulva	0.001	0.986	0.013
M77 Other enthesopathies	0.013	0.986	0.000
C16.9 Stomach, unspecified	0.000	0.986	0.013
F05 Delirium, not induced by alcohol and other psychoactive substances	0.013	0.986	0.000
G44.2 Tension-type headache	0.013	0.986	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.986	0.013
R94 Abnormal results of function studies	0.013	0.986	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.013	0.986	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.013	0.986	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.013	0.986	0.000
A80-A89 Viral infections of the central nervous system	0.013	0.986	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.013	0.987	0.000
I99 Other and unspecified disorders of circulatory system	0.013	0.987	0.000
C16.6 Greater curvature of stomach, unspecified	0.000	0.987	0.013
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.013	0.987	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.013	0.987	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.013	0.987	0.000
R07.1 Chest pain on breathing	0.013	0.987	0.000
H80-H83 Diseases of inner ear	0.013	0.987	0.000
G62.9 Polyneuropathy, unspecified	0.013	0.987	0.000
G50 Disorders of trigeminal nerve	0.013	0.987	0.000
C18.7 Sigmoid colon	0.000	0.987	0.013
R09.2 Respiratory arrest	0.013	0.987	0.000
R09.0 Asphyxia	0.013	0.987	0.000
F00 Dementia in Alzheimer's disease	0.013	0.987	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.013	0.987	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.013	0.987	0.000
I40 Acute myocarditis	0.013	0.987	0.000
I33 Acute and subacute endocarditis	0.013	0.987	0.000
M81.98 Osteoporosis, unspecified (Other)	0.013	0.987	0.000
R05 Cough	0.013	0.987	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.013	0.987	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.013	0.987	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.013	0.987	0.000
F03 Unspecified dementia	0.013	0.987	0.000
G36 Other acute disseminated demyelination	0.013	0.987	0.000
I30 Acute pericarditis	0.013	0.987	0.000
I67 Other cerebrovascular diseases	0.013	0.987	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.013	0.987	0.000
G81 Hemiplegia	0.013	0.987	0.000
R40.0 Somnolence	0.013	0.987	0.000
C58 Malignant neoplasm of placenta	0.001	0.987	0.013
I36 Nonrheumatic tricuspid valve disorders	0.013	0.987	0.000
I38 Endocarditis, valve unspecified	0.013	0.987	0.000
M71 Other bursopathies	0.013	0.987	0.000
R45.8 Other symptoms and signs involving emotional state	0.013	0.987	0.000
G21 Secondary Parkinsonism	0.013	0.987	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.013	0.987	0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.013	0.987	0.000
I52 Other heart disorders in diseases classified elsewhere	0.013	0.987	0.000
I48 Atrial fibrillation and flutter	0.013	0.987	0.000
I41 Myocarditis in diseases classified elsewhere	0.013	0.987	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.013	0.987	0.000
I32 Pericarditis in diseases classified elsewhere	0.013	0.987	0.000
I37 Pulmonary valve disorders	0.013	0.987	0.000
C18.4 Transverse colon	0.000	0.987	0.013
R06.8 Other and unspecified abnormalities of breathing	0.013	0.987	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.013	0.987	0.000
G23 Other degenerative diseases of basal ganglia	0.013	0.987	0.000
I44.7 Left bundle-branch block, unspecified	0.013	0.987	0.000
D80-D89 Certain disorders involving the immune mechanism	0.013	0.987	0.000
M81.2 Osteoporosis of disuse	0.013	0.987	0.000
A65-A69 Other spirochaetal diseases	0.013	0.987	0.000
R47.0 Dysphasia and aphasia	0.013	0.987	0.000
C88 Malignant immunoproliferative diseases	0.001	0.987	0.013
D07 Carcinoma in situ of other and unspecified genital organs	0.001	0.987	0.013
B35-B49 Mycoses	0.013	0.987	0.000
C86 Other specified types of T/NK-cell lymphoma	0.001	0.987	0.013
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.013	0.987	0.000
G22 Parkinsonism in diseases classified elsewhere	0.013	0.987	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.013	0.987	0.000
R44.2 Other hallucinations	0.013	0.987	0.000
C34 Malignant neoplasm of bronchus and lung	0.001	0.987	0.013
K70 Alcoholic liver disease	0.013	0.987	0.000
M81.0 Postmenopausal osteoporosis	0.013	0.987	0.000
G03 Meningitis due to other and unspecified causes	0.013	0.987	0.000
G57 Mononeuropathies of lower limb	0.013	0.987	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.013	0.987	0.000
A15-A19 Tuberculosis	0.013	0.987	0.000
C17.2 Ileum	0.000	0.987	0.013
G80 Infantile cerebral palsy	0.013	0.987	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.013	0.987	0.000
M45-M49 Spondylopathies	0.013	0.987	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.987	0.013
C77.1 Intrathoracic lymph nodes	0.000	0.987	0.013
M75.3 Calcific tendinitis of shoulder	0.013	0.987	0.000
G83 Other paralytic syndromes	0.013	0.987	0.000
A20-A28 Certain zoonotic bacterial diseases	0.013	0.987	0.000
M81.8 Other osteoporosis	0.013	0.987	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.013	0.987	0.000
M81.1 Postoophorectomy osteoporosis	0.013	0.987	0.000
R44.0 Auditory hallucinations	0.013	0.987	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.001	0.987	0.012
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.013	0.987	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.013	0.987	0.000
A75-A79 Rickettsioses	0.013	0.987	0.000
A70-A74 Other diseases caused by chlamydiae	0.013	0.987	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.013	0.987	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.013	0.987	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.013	0.987	0.000
B65-B83 Helminthiases	0.013	0.987	0.000
B50-B64 Protozoal diseases	0.013	0.987	0.000
C16.8 Overlapping lesion of stomach	0.000	0.987	0.013
M81.6 Localised osteoporosis [Lequesne]	0.013	0.987	0.000
M81.5 Idiopathic osteoporosis	0.013	0.987	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.013	0.987	0.000
M72 Fibroblastic disorders	0.013	0.987	0.000
C95 Leukaemia of unspecified cell type	0.001	0.987	0.012
C84 Peripheral and cutaneous T-cell lymphomas	0.001	0.987	0.012
G01 Meningitis in bacterial diseases classified elsewhere	0.013	0.987	0.000
C16.4 Pylorus	0.000	0.987	0.013
C16.1 Fundus of stomach	0.000	0.987	0.013
G47.4 Narcolepsy and cataplexy	0.013	0.987	0.000
G60 Hereditary and idiopathic neuropathy	0.013	0.987	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.013	0.987	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.013	0.987	0.000
C18.5 Splenic flexure	0.000	0.987	0.013
M75.9 Shoulder lesion, unspecified	0.013	0.987	0.000
K55-K64 Other diseases of intestines	0.013	0.987	0.000
I69.3 Sequelae of cerebral infarction	0.013	0.987	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.001	0.987	0.012
S60 Superficial injury of wrist and hand	0.013	0.987	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.013	0.987	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.013	0.987	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.013	0.987	0.000
C16.2 Body of stomach	0.000	0.987	0.013
M75.5 Bursitis of shoulder	0.013	0.987	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.013	0.987	0.000
R45.2 Unhappiness	0.013	0.987	0.000
G11 Hereditary ataxia	0.013	0.987	0.000
N34 Urethritis and urethral syndrome	0.013	0.987	0.000
B25-B34 Other viral diseases	0.013	0.987	0.000
S80-S89 Injuries to the knee and lower leg	0.013	0.987	0.000
C15.8 Overlapping lesion of oesophagus	0.000	0.987	0.013
C15.2 Abdominal part of oesophagus	0.000	0.987	0.013
I84.8 Unspecified haemorrhoids with other complications	0.013	0.987	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.001	0.987	0.012
G37 Other demyelinating diseases of central nervous system	0.013	0.987	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.013	0.987	0.000
M41 Scoliosis	0.013	0.987	0.000
R80 Isolated proteinuria	0.013	0.987	0.000
C50-C50 Malignant neoplasm of breast	0.002	0.987	0.011
K40-K46 Hernia	0.013	0.987	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.013	0.987	0.000
C16.3 Pyloric antrum	0.000	0.987	0.013
G47.2 Disorders of the sleep-wake schedule	0.013	0.987	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.013	0.987	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.987	0.013
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.013	0.987	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.013	0.987	0.000
G51 Facial nerve disorders	0.013	0.987	0.000
I26 Pulmonary embolism	0.013	0.987	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.013	0.987	0.000
N25-N29 Other disorders of kidney and ureter	0.013	0.987	0.000
C15.5 Lower third of oesophagus	0.000	0.987	0.013
C15.1 Thoracic part of oesophagus	0.000	0.987	0.013
F17.1 Harmful use	0.013	0.987	0.000
R45.0 Nervousness	0.013	0.987	0.000
C94 Other leukaemias of specified cell type	0.001	0.987	0.012
G95 Other diseases of spinal cord	0.013	0.987	0.000
R23 Other skin changes	0.013	0.987	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.013	0.987	0.000
I51.9 Heart disease, unspecified	0.013	0.987	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.013	0.987	0.000
D55-D59 Haemolytic anaemias	0.013	0.987	0.000
N17-N19 Renal failure	0.013	0.987	0.000
C15.0 Cervical part of oesophagus	0.000	0.987	0.013
C16.0 Cardia	0.000	0.987	0.013
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.013	0.987	0.000
C93 Monocytic leukaemia	0.001	0.987	0.012
R45.4 Irritability and anger	0.013	0.987	0.000
F01 Vascular dementia	0.013	0.987	0.000
K90 Intestinal malabsorption	0.013	0.987	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.013	0.987	0.000
C21.2 Cloacogenic zone	0.000	0.987	0.012
K76.9 Liver disease, unspecified	0.013	0.987	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.013	0.987	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations