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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12511037
log Bayes Factor = 1.75425
Chromosome 4   position 75,334,864  (GRCh37) Explore rs12511037 on Ensembl!
Variant rs12511037 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
O60-O75 Complications of labour and delivery
0.981 0.019 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.980 0.020 0.000
O72 Postpartum haemorrhage
0.967 0.033 0.000
# Top node
0.961 0.039 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.945 0.055 0.000
Chapter I Certain infectious and parasitic diseases
0.932 0.068 0.000
M70-M79 Other soft tissue disorders
0.927 0.073 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.923 0.077 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.921 0.079 0.000
Chapter XX External causes of morbidity and mortality
0.914 0.086 0.000
O72.1 Other immediate postpartum haemorrhage
0.913 0.087 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.909 0.091 0.000
M79.6 Pain in limb
0.905 0.095 0.000
B95-B98 Bacterial, viral and other infectious agents
0.904 0.096 0.000
M80-M85 Disorders of bone density and structure
0.900 0.100 0.000
Chapter VI Diseases of the nervous system
0.900 0.100 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.898 0.102 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.888 0.112 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.886 0.114 0.000
O72.0 Third-stage haemorrhage
0.886 0.114 0.000
M79.66 Pain in limb (Lower leg)
0.877 0.123 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.873 0.127 0.000
O00-O08 Pregnancy with abortive outcome
0.873 0.127 0.000
A30-A49 Other bacterial diseases
0.871 0.129 0.000
M81 Osteoporosis without pathological fracture
0.867 0.133 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.865 0.135 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.857 0.143 0.000
G20-G26 Extrapyramidal and movement disorders
0.854 0.146 0.000
M79.60 Pain in limb (Multiple sites)
0.849 0.151 0.000
M81.9 Osteoporosis, unspecified
0.845 0.155 0.000
O02 Other abnormal products of conception
0.843 0.157 0.000
S80-S89 Injuries to the knee and lower leg
0.836 0.164 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.834 0.166 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.829 0.171 0.000
Chapter IX Diseases of the circulatory system
0.827 0.173 0.000
I60-I69 Cerebrovascular diseases
0.827 0.173 0.000
G20 Parkinson's disease
0.827 0.173 0.000
O66 Other obstructed labour
0.821 0.179 0.000
Chapter XIV Diseases of the genitourinary system
0.819 0.181 0.000
O02.1 Missed abortion
0.819 0.181 0.000
M79.0 Rheumatism, unspecified
0.819 0.181 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.816 0.184 0.000
M45-M49 Spondylopathies
0.814 0.186 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.813 0.186 0.000
M79.7 Fibromyalgia
0.810 0.190 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.810 0.190 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.810 0.190 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.808 0.192 0.000
Chapter XXII Codes for special purposes
0.807 0.193 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.802 0.198 0.000
O62 Abnormalities of forces of labour
0.797 0.203 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.792 0.208 0.000
N60-N64 Disorders of breast
0.788 0.212 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.787 0.213 0.000
I69 Sequelae of cerebrovascular disease
0.784 0.216 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.782 0.218 0.000
G30-G32 Other degenerative diseases of the nervous system
0.779 0.221 0.000
A41 Other septicaemia
0.776 0.224 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.776 0.224 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.773 0.227 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.771 0.229 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.768 0.232 0.000
N87 Dysplasia of cervix uteri
0.765 0.235 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.761 0.239 0.000
I60 Subarachnoid haemorrhage
0.760 0.240 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.760 0.240 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.758 0.242 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.758 0.242 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.758 0.242 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.755 0.245 0.000
M71 Other bursopathies
0.755 0.245 0.000
M79.1 Myalgia
0.752 0.248 0.000
S80 Superficial injury of lower leg
0.747 0.253 0.000
M05-M14 Inflammatory polyarthropathies
0.743 0.257 0.000
A41.9 Septicaemia, unspecified
0.737 0.263 0.000
O20 Haemorrhage in early pregnancy
0.736 0.264 0.000
O28 Abnormal findings on antenatal screening of mother
0.736 0.264 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.733 0.267 0.000
Y84.6 Urinary catheterisation
0.731 0.269 0.000
M79.79 Fibromyalgia (Site unspecified)
0.730 0.270 0.000
M40-M43 Deforming dorsopathies
0.729 0.271 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.728 0.272 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.726 0.274 0.000
Y52 Agents primarily affecting the cardiovascular system
0.726 0.274 0.000
Y84.8 Other medical procedures
0.726 0.274 0.000
O61 Failed induction of labour
0.725 0.275 0.000
O21 Excessive vomiting in pregnancy
0.725 0.275 0.000
A46 Erysipelas
0.724 0.276 0.000
N64 Other disorders of breast
0.723 0.277 0.000
B50-B64 Protozoal diseases
0.722 0.278 0.000
O85-O92 Complications predominantly related to the puerperium
0.720 0.280 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.720 0.280 0.000
G90-G99 Other disorders of the nervous system
0.719 0.281 0.000
S90-S99 Injuries to the ankle and foot
0.715 0.285 0.000
M45 Ankylosing spondylitis
0.715 0.285 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.709 0.291 0.000
T93 Sequelae of injuries of lower limb
0.707 0.293 0.000
N87.0 Mild cervical dysplasia
0.706 0.294 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.704 0.296 0.000
O74 Complications of anaesthesia during labour and delivery
0.703 0.296 0.000
O71 Other obstetric trauma
0.703 0.296 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.703 0.296 0.000
O60 Preterm delivery
0.703 0.296 0.000
M60-M63 Disorders of muscles
0.703 0.297 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.703 0.297 0.000
M84 Disorders of continuity of bone
0.702 0.298 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.702 0.298 0.000
G35 Multiple sclerosis
0.702 0.298 0.000
O75.0 Maternal distress during labour and delivery
0.700 0.300 0.000
O63 Long labour
0.699 0.301 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.698 0.302 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.697 0.303 0.000
M00-M03 Infectious arthropathies
0.697 0.303 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.695 0.305 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.695 0.305 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.694 0.306 0.000
O72.3 Postpartum coagulation defects
0.694 0.306 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.694 0.306 0.000
W00-W19 Falls
0.693 0.307 0.000
S82 Fracture of lower leg, including ankle
0.691 0.309 0.000
O75.8 Other specified complications of labour and delivery
0.691 0.309 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.690 0.310 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.689 0.311 0.000
N61 Inflammatory disorders of breast
0.689 0.311 0.000
O24 Diabetes mellitus in pregnancy
0.689 0.311 0.000
Y48 Anaesthetics and therapeutic gases
0.689 0.311 0.000
X20-X29 Contact with venomous animals and plants
0.688 0.311 0.000
T90 Sequelae of injuries of head
0.688 0.312 0.000
S70-S79 Injuries to the hip and thigh
0.686 0.314 0.000
M91-M94 Chondropathies
0.685 0.315 0.000
V80-V89 Other land transport accidents
0.685 0.315 0.000
B99-B99 Other infectious diseases
0.683 0.317 0.000
B65-B83 Helminthiases
0.682 0.318 0.000
G70-G73 Diseases of myoneural junction and muscle
0.681 0.319 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.680 0.320 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.680 0.320 0.000
A49 Bacterial infection of unspecified site
0.679 0.321 0.000
I20-I25 Ischaemic heart diseases
0.678 0.322 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.677 0.322 0.000
N85.0 Endometrial glandular hyperplasia
0.677 0.323 0.000
A80-A89 Viral infections of the central nervous system
0.677 0.323 0.000
S50-S59 Injuries to the elbow and forearm
0.676 0.324 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.675 0.325 0.000
M79.62 Pain in limb (Upper arm)
0.673 0.327 0.000
O73 Retained placenta and membranes, without haemorrhage
0.672 0.328 0.000
I62 Other nontraumatic intracranial haemorrhage
0.669 0.331 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.668 0.332 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.668 0.332 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.668 0.332 0.000
A75-A79 Rickettsioses
0.668 0.332 0.000
A70-A74 Other diseases caused by chlamydiae
0.668 0.332 0.000
A65-A69 Other spirochaetal diseases
0.668 0.332 0.000
A20-A28 Certain zoonotic bacterial diseases
0.668 0.332 0.000
A15-A19 Tuberculosis
0.668 0.332 0.000
M86-M90 Other osteopathies
0.668 0.332 0.000
S10-S19 Injuries to the neck
0.668 0.332 0.000
M85 Other disorders of bone density and structure
0.668 0.332 0.000
Y57 Other and unspecified drugs and medicaments
0.666 0.334 0.000
M47 Spondylosis
0.665 0.335 0.000
S80.9 Superficial injury of lower leg, unspecified
0.665 0.335 0.000
M76 Enthesopathies of lower limb, excluding foot
0.665 0.335 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.665 0.335 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.665 0.335 0.000
O62.2 Other uterine inertia
0.664 0.336 0.000
T66-T78 Other and unspecified effects of external causes
0.664 0.336 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.664 0.336 0.000
N64.5 Other signs and symptoms in breast
0.663 0.337 0.000
M79.9 Soft tissue disorder, unspecified
0.662 0.338 0.000
M79.5 Residual foreign body in soft tissue
0.662 0.338 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.662 0.338 0.000
M79.3 Panniculitis, unspecified
0.662 0.338 0.000
M79.2 Neuralgia and neuritis, unspecified
0.662 0.338 0.000
T81 Complications of procedures, not elsewhere classified
0.661 0.339 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.661 0.339 0.000
O43 Placental disorders
0.661 0.339 0.000
O75.9 Complication of labour and delivery, unspecified
0.660 0.339 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.660 0.339 0.000
O75.4 Other complications of obstetric surgery and procedures
0.660 0.339 0.000
O75.3 Other infection during labour
0.660 0.339 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.660 0.339 0.000
O75.1 Shock during or following labour and delivery
0.660 0.339 0.000
Y40 Systemic antibiotics
0.657 0.343 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.656 0.344 0.000
Y35-Y36 Legal intervention and operations of war
0.655 0.345 0.000
Y10-Y34 Event of undetermined intent
0.655 0.345 0.000
Y00-Y09 Assault
0.655 0.345 0.000
X85-X99 Assault
0.655 0.345 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.655 0.345 0.000
X50-X57 Overexertion, travel and privation
0.655 0.345 0.000
X30-X39 Exposure to forces of nature
0.655 0.345 0.000
X10-X19 Contact with heat and hot substances
0.655 0.345 0.000
X00-X09 Exposure to smoke, fire and flames
0.655 0.345 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.655 0.345 0.000
W75-W84 Other accidental threats to breathing
0.655 0.345 0.000
W65-W74 Accidental drowning and submersion
0.655 0.345 0.000
W50-W64 Exposure to animate mechanical forces
0.655 0.345 0.000
V98-V99 Other and unspecified transport accidents
0.655 0.345 0.000
V95-V97 Air and space transport accidents
0.655 0.345 0.000
V90-V94 Water transport accidents
0.655 0.345 0.000
V70-V79 Bus occupant injured in transport accident
0.655 0.345 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.655 0.345 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.655 0.345 0.000
V40-V49 Car occupant injured in transport accident
0.655 0.345 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.655 0.345 0.000
V01-V09 Pedestrian injured in transport accident
0.655 0.345 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.655 0.345 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.654 0.346 0.000
T33-T35 Frostbite
0.652 0.348 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.652 0.348 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.652 0.348 0.000
T00-T07 Injuries involving multiple body regions
0.652 0.348 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.650 0.350 0.000
M72 Fibroblastic disorders
0.650 0.350 0.000
N85.2 Hypertrophy of uterus
0.649 0.351 0.000
M79.68 Pain in limb (Other)
0.649 0.351 0.000
M79.61 Pain in limb (Shoulder region)
0.649 0.351 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.647 0.353 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.647 0.353 0.000
V10-V19 Pedal cyclist injured in transport accident
0.646 0.353 0.000
M83 Adult osteomalacia
0.645 0.354 0.000
M82 Osteoporosis in diseases classified elsewhere
0.645 0.354 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.644 0.356 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.644 0.356 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.643 0.357 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.642 0.358 0.000
S20-S29 Injuries to the thorax
0.642 0.358 0.000
T86 Failure and rejection of transplanted organs and tissues
0.641 0.359 0.000
S40-S49 Injuries to the shoulder and upper arm
0.641 0.359 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.640 0.359 0.000
M13 Other arthritis
0.639 0.361 0.000
U80 Agent resistant to penicillin and related antibiotics
0.638 0.362 0.000
S89 Other and unspecified injuries of lower leg
0.637 0.363 0.000
O29 Complications of anaesthesia during pregnancy
0.637 0.363 0.000
O22 Venous complications in pregnancy
0.637 0.363 0.000
O25 Malnutrition in pregnancy
0.637 0.363 0.000
I69.3 Sequelae of cerebral infarction
0.637 0.363 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.636 0.364 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.636 0.364 0.000
V20-V29 Motorcycle rider injured in transport accident
0.636 0.364 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.636 0.364 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.635 0.365 0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters
0.635 0.365 0.000
N89 Other noninflammatory disorders of vagina
0.635 0.365 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.633 0.366 0.000
N87.2 Severe cervical dysplasia, not elsewhere classified
0.633 0.367 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.632 0.368 0.000
T79-T79 Certain early complications of trauma
0.631 0.369 0.000
O23 Infections of genito-urinary tract in pregnancy
0.630 0.370 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.630 0.370 0.000
Q80-Q89 Other congenital malformations
0.629 0.371 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.629 0.371 0.000
G31.8 Other specified degenerative diseases of nervous system
0.628 0.372 0.000
O00 Ectopic pregnancy
0.627 0.373 0.000
N60 Benign mammary dysplasia
0.627 0.373 0.000
M79.69 Pain in limb (Site unspecified)
0.627 0.373 0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother
0.626 0.374 0.000
T93.1 Sequelae of fracture of femur
0.626 0.374 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.626 0.374 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.626 0.374 0.000
O07 Failed attempted abortion
0.626 0.374 0.000
O06 Unspecified abortion
0.626 0.374 0.000
O05 Other abortion
0.626 0.374 0.000
O01 Hydatidiform mole
0.626 0.374 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.625 0.375 0.000
Y44 Agents primarily affecting blood constituents
0.625 0.375 0.000
T14 Injury of unspecified body region
0.625 0.375 0.000
T11 Other injuries of upper limb, level unspecified
0.625 0.375 0.000
A48 Other bacterial diseases, not elsewhere classified
0.624 0.376 0.000
A44 Bartonellosis
0.624 0.376 0.000
A43 Nocardiosis
0.624 0.376 0.000
A42 Actinomycosis
0.624 0.376 0.000
A40 Streptococcal septicaemia
0.624 0.376 0.000
A39 Meningococcal infection
0.624 0.376 0.000
A37 Whooping cough
0.624 0.376 0.000
A36 Diphtheria
0.624 0.376 0.000
A32 Listeriosis
0.624 0.376 0.000
A31 Infection due to other mycobacteria
0.624 0.376 0.000
A30 Leprosy [Hansen's disease]
0.624 0.376 0.000
A38 Scarlet fever
0.624 0.376 0.000
A35 Other tetanus
0.624 0.376 0.000
A34 Obstetrical tetanus
0.624 0.376 0.000
A33 Tetanus neonatorum
0.624 0.376 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.623 0.377 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.623 0.377 0.000
W20-W49 Exposure to inanimate mechanical forces
0.623 0.377 0.000
M81.8 Other osteoporosis
0.622 0.378 0.000
M81.6 Localised osteoporosis [Lequesne]
0.622 0.378 0.000
M81.5 Idiopathic osteoporosis
0.622 0.378 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.622 0.378 0.000
M81.2 Osteoporosis of disuse
0.622 0.378 0.000
M81.1 Postoophorectomy osteoporosis
0.622 0.378 0.000
M81.0 Postmenopausal osteoporosis
0.622 0.378 0.000
S86 Injury of muscle and tendon at lower leg level
0.622 0.378 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.622 0.378 0.000
X60-X84 Intentional self-harm
0.621 0.379 0.000
G24 Dystonia
0.620 0.380 0.000
O40 Polyhydramnios
0.620 0.380 0.000
N00-N08 Glomerular diseases
0.620 0.380 0.000
M81.98 Osteoporosis, unspecified (Other)
0.620 0.380 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.617 0.383 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.617 0.383 0.000
M79.67 Pain in limb (Ankle and foot)
0.616 0.384 0.000
A41.8 Other specified septicaemia
0.616 0.384 0.000
O67.9 Intrapartum haemorrhage, unspecified
0.616 0.384 0.000
Y59 Other and unspecified vaccines and biological substances
0.615 0.385 0.000
Y58 Bacterial vaccines
0.615 0.385 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.615 0.385 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.615 0.385 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.615 0.385 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.615 0.385 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.615 0.385 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.615 0.385 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.615 0.385 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.615 0.385 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.614 0.386 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.613 0.387 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.613 0.387 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.613 0.387 0.000
N99-N99 Other disorders of the genitourinary system
0.613 0.387 0.000
G23 Other degenerative diseases of basal ganglia
0.612 0.388 0.000
G21 Secondary Parkinsonism
0.612 0.388 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.612 0.388 0.000
G22 Parkinsonism in diseases classified elsewhere
0.612 0.388 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.612 0.388 0.000
N80 Endometriosis
0.612 0.388 0.000
B15-B19 Viral hepatitis
0.611 0.389 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.611 0.389 0.000
N91 Absent, scanty and rare menstruation
0.610 0.389 0.000
M79.18 Myalgia (Other)
0.610 0.390 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.608 0.392 0.000
Chapter VII Diseases of the eye and adnexa
0.608 0.392 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.606 0.394 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.606 0.394 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.606 0.394 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.606 0.394 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.606 0.394 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.606 0.394 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.606 0.394 0.000
O02.9 Abnormal product of conception, unspecified
0.604 0.395 0.000
O02.8 Other specified abnormal products of conception
0.604 0.395 0.000
M06 Other rheumatoid arthritis
0.603 0.397 0.000
M79.63 Pain in limb (Forearm)
0.602 0.398 0.000
M81.4 Drug-induced osteoporosis
0.601 0.399 0.000
G37 Other demyelinating diseases of central nervous system
0.601 0.399 0.000
Q60-Q64 Congenital malformations of the urinary system
0.601 0.399 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.600 0.400 0.000
N64.1 Fat necrosis of breast
0.600 0.400 0.000
S88 Traumatic amputation of lower leg
0.599 0.401 0.000
S87 Crushing injury of lower leg
0.599 0.401 0.000
S85 Injury of blood vessels at lower leg level
0.599 0.401 0.000
S84 Injury of nerves at lower leg level
0.599 0.401 0.000
T98 Sequelae of other and unspecified effects of external causes
0.599 0.401 0.000
T87 Complications peculiar to reattachment and amputation
0.598 0.402 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.597 0.403 0.000
I20 Angina pectoris
0.596 0.404 0.000
Chapter VIII Diseases of the ear and mastoid process
0.596 0.404 0.000
M47.9 Spondylosis, unspecified
0.594 0.406 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.593 0.406 0.000
N95 Menopausal and other perimenopausal disorders
0.593 0.407 0.000
I00-I02 Acute rheumatic fever
0.593 0.407 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.593 0.407 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.593 0.407 0.000
M46 Other inflammatory spondylopathies
0.592 0.407 0.000
G93 Other disorders of brain
0.592 0.408 0.000
B35-B49 Mycoses
0.592 0.408 0.000
B07 Viral warts
0.589 0.411 0.000
O21.9 Vomiting of pregnancy, unspecified
0.589 0.411 0.000
O66.9 Obstructed labour, unspecified
0.588 0.411 0.000
O66.8 Other specified obstructed labour
0.588 0.411 0.000
O66.4 Failed trial of labour, unspecified
0.588 0.411 0.000
O66.3 Obstructed labour due to other abnormalities of foetus
0.588 0.411 0.000
O66.2 Obstructed labour due to unusually large foetus
0.588 0.411 0.000
O66.1 Obstructed labour due to locked twins
0.588 0.411 0.000
M79.08 Rheumatism, unspecified (Other)
0.587 0.413 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.587 0.413 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.587 0.413 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.587 0.413 0.000
M79.04 Rheumatism, unspecified (Hand)
0.587 0.413 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.587 0.413 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.587 0.413 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.587 0.413 0.000
N85.6 Intra-uterine synechiae
0.587 0.413 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.587 0.413 0.000
S80.8 Other superficial injuries of lower leg
0.586 0.414 0.000
M41 Scoliosis
0.586 0.414 0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified
0.585 0.415 0.000
O64.8 Obstructed labour due to other malposition and malpresentation
0.585 0.415 0.000
O64.5 Obstructed labour due to compound presentation
0.585 0.415 0.000
O64.4 Obstructed labour due to shoulder presentation
0.585 0.415 0.000
O64.3 Obstructed labour due to brow presentation
0.585 0.415 0.000
O64.2 Obstructed labour due to face presentation
0.585 0.415 0.000
O64.1 Obstructed labour due to breech presentation
0.585 0.415 0.000
M49 Spondylopathies in diseases classified elsewhere
0.583 0.417 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.583 0.417 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.583 0.417 0.000
O97 Death from sequelae of direct obstetric causes
0.583 0.417 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.583 0.417 0.000
O95 Obstetric death of unspecified cause
0.583 0.417 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.583 0.417 0.000
S82.6 Fracture of lateral malleolus
0.583 0.417 0.000
N85.1 Endometrial adenomatous hyperplasia
0.583 0.417 0.000
N86 Erosion and ectropion of cervix uteri
0.582 0.418 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.581 0.419 0.000
M79.78 Fibromyalgia (Other)
0.581 0.419 0.000
M79.77 Fibromyalgia (Ankle and foot)
0.581 0.419 0.000
M79.76 Fibromyalgia (Lower leg)
0.581 0.419 0.000
M79.75 Fibromyalgia (Pelvic region and thigh)
0.581 0.419 0.000
M79.74 Fibromyalgia (Hand)
0.581 0.419 0.000
M79.73 Fibromyalgia (Forearm)
0.581 0.419 0.000
M79.72 Fibromyalgia (Upper arm)
0.581 0.419 0.000
M79.71 Fibromyalgia (Shoulder region)
0.581 0.419 0.000
M79.70 Fibromyalgia (Multiple sites)
0.581 0.419 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.581 0.419 0.000
T95 Sequelae of burns, corrosions and frostbite
0.581 0.419 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.581 0.419 0.000
T91 Sequelae of injuries of neck and trunk
0.581 0.419 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.581 0.419 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.581 0.419 0.000
O43.8 Other placental disorders
0.581 0.419 0.000
N62 Hypertrophy of breast
0.580 0.420 0.000
N70 Salpingitis and oophoritis
0.579 0.421 0.000
M84.0 Malunion of fracture
0.579 0.421 0.000
N75 Diseases of Bartholin's gland
0.578 0.422 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.576 0.424 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.576 0.424 0.000
T90.9 Sequelae of unspecified injury of head
0.576 0.424 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.575 0.425 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.575 0.425 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.574 0.426 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.574 0.426 0.000
B25-B34 Other viral diseases
0.573 0.427 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.572 0.428 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.572 0.428 0.000
B50 Plasmodium falciparum malaria
0.571 0.428 0.000
O62.9 Abnormality of forces of labour, unspecified
0.571 0.429 0.000
O62.8 Other abnormalities of forces of labour
0.571 0.429 0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions
0.571 0.429 0.000
O62.3 Precipitate labour
0.571 0.429 0.000
O62.1 Secondary uterine inertia
0.571 0.429 0.000
O62.0 Primary inadequate contractions
0.571 0.429 0.000
Y84.1 Kidney dialysis
0.570 0.430 0.000
Q50-Q56 Congenital malformations of genital organs
0.570 0.430 0.000
I22 Subsequent myocardial infarction
0.570 0.430 0.000
M79.19 Myalgia (Site unspecified)
0.569 0.431 0.000
O42 Premature rupture of membranes
0.568 0.431 0.000
G36 Other acute disseminated demyelination
0.568 0.432 0.000
Y48.4 Anaesthetic, unspecified
0.568 0.432 0.000
N82 Fistulae involving female genital tract
0.568 0.432 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.566 0.434 0.000
M65-M68 Disorders of synovium and tendon
0.566 0.434 0.000
I61 Intracerebral haemorrhage
0.565 0.435 0.000
G30 Alzheimer's disease
0.565 0.435 0.000
H53-H54 Visual disturbances and blindness
0.565 0.435 0.000
S99 Other and unspecified injuries of ankle and foot
0.564 0.436 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.564 0.436 0.000
Q35-Q37 Cleft lip and cleft palate
0.564 0.436 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.564 0.436 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.564 0.436 0.000
N72 Inflammatory disease of cervix uteri
0.562 0.438 0.000
S82.4 Fracture of fibula alone
0.562 0.438 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.562 0.438 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.562 0.438 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.562 0.438 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.562 0.438 0.000
I20.8 Other forms of angina pectoris
0.561 0.439 0.000
S82.0 Fracture of patella
0.561 0.439 0.000
N98 Complications associated with artificial fertilisation
0.561 0.439 0.000
N96 Habitual aborter
0.561 0.439 0.000
Y52.1 Calcium-channel blockers
0.561 0.439 0.000
T82.3 Mechanical complication of other vascular grafts
0.561 0.439 0.000
A49.0 Staphylococcal infection, unspecified
0.560 0.440 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.559 0.440 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.559 0.441 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.558 0.442 0.000
S50 Superficial injury of forearm
0.558 0.442 0.000
Y42.5 Other oestrogens and progestogens
0.557 0.443 0.000
M47.2 Other spondylosis with radiculopathy
0.557 0.443 0.000
A41.4 Septicaemia due to anaerobes
0.557 0.443 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.557 0.443 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.557 0.443 0.000
Y84.9 Medical procedure, unspecified
0.557 0.443 0.000
Y84.7 Blood-sampling
0.557 0.443 0.000
Y84.5 Insertion of gastric or duodenal sound
0.557 0.443 0.000
Y84.4 Aspiration of fluid
0.557 0.443 0.000
Y84.3 Shock therapy
0.557 0.443 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.557 0.443 0.000
U80.1 Methicillin resistant agent
0.556 0.444 0.000
G90 Disorders of autonomic nervous system
0.556 0.444 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.555 0.445 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.555 0.445 0.000
O20.8 Other haemorrhage in early pregnancy
0.554 0.445 0.000
M79.64 Pain in limb (Hand)
0.554 0.446 0.000
O45 Premature separation of placenta [abruptio placentae]
0.554 0.446 0.000
O33 Maternal care for known or suspected disproportion
0.554 0.446 0.000
O31 Complications specific to multiple gestation
0.554 0.446 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.554 0.446 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.553 0.447 0.000
N71 Inflammatory disease of uterus, except cervix
0.553 0.447 0.000
T13 Other injuries of lower limb, level unspecified
0.553 0.447 0.000
T09 Other injuries of spine and trunk, level unspecified
0.553 0.447 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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