TreeWAS – Variant ID: rs12515838

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter I Certain infectious and parasitic diseases	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
Chapter IX Diseases of the circulatory system	0.998	0.002
I30-I52 Other forms of heart disease	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.997	0.003
I42 Cardiomyopathy	0.995	0.005
J09-J18 Influenza and pneumonia	0.989	0.011
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.982	0.018
A00-A09 Intestinal infectious diseases	0.979	0.021
I44 Atrioventricular and left bundle-branch block	0.971	0.029
J80-J84 Other respiratory diseases principally affecting the interstitium	0.970	0.030
I60-I69 Cerebrovascular diseases	0.953	0.047
B35-B49 Mycoses	0.949	0.051
J18 Pneumonia, organism unspecified	0.947	0.053
Chapter XXII Codes for special purposes	0.944	0.056
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.944	0.056
Chapter IV Endocrine, nutritional and metabolic diseases	0.943	0.057
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.942	0.058
J40-J47 Chronic lower respiratory diseases	0.942	0.058
I44.7 Left bundle-branch block, unspecified	0.934	0.066
A30-A49 Other bacterial diseases	0.931	0.069
I42.2 Other hypertrophic cardiomyopathy	0.930	0.070
I42.0 Dilated cardiomyopathy	0.930	0.070
E70-E90 Metabolic disorders	0.930	0.070
B95-B98 Bacterial, viral and other infectious agents	0.930	0.070
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.928	0.072
J18.1 Lobar pneumonia, unspecified	0.927	0.073
S20-S29 Injuries to the thorax	0.925	0.075
Chapter XX External causes of morbidity and mortality	0.919	0.081
Chapter VII Diseases of the eye and adnexa	0.916	0.084
Chapter VIII Diseases of the ear and mastoid process	0.916	0.084
Chapter XIV Diseases of the genitourinary system	0.911	0.089
I67 Other cerebrovascular diseases	0.911	0.089
E87 Other disorders of fluid, electrolyte and acid-base balance	0.910	0.090
I42.9 Cardiomyopathy, unspecified	0.909	0.091
B37 Candidiasis	0.906	0.094
N17-N19 Renal failure	0.903	0.097
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.898	0.102
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.898	0.102
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.897	0.103
J00-J06 Acute upper respiratory infections	0.892	0.108
I42.1 Obstructive hypertrophic cardiomyopathy	0.886	0.114
N17 Acute renal failure	0.885	0.115
A49 Bacterial infection of unspecified site	0.884	0.116
J44 Other chronic obstructive pulmonary disease	0.880	0.120
T84.1 Mechanical complication of internal fixation device of bones of limb	0.878	0.122
M50-M54 Other dorsopathies	0.876	0.124
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.871	0.129
J15 Bacterial pneumonia, not elsewhere classified	0.870	0.130
J84 Other interstitial pulmonary diseases	0.869	0.131
M70-M79 Other soft tissue disorders	0.869	0.131
H90-H95 Other disorders of ear	0.868	0.132
I44.2 Atrioventricular block, complete	0.868	0.132
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.868	0.132
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.866	0.134
N17.9 Acute renal failure, unspecified	0.864	0.136
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.861	0.139
S27 Injury of other and unspecified intrathoracic organs	0.861	0.139
J40 Bronchitis, not specified as acute or chronic	0.860	0.140
S00-S09 Injuries to the head	0.859	0.141
J81 Pulmonary oedema	0.858	0.142
M86-M90 Other osteopathies	0.858	0.142
M20-M25 Other joint disorders	0.853	0.147
I60 Subarachnoid haemorrhage	0.853	0.147
T79-T79 Certain early complications of trauma	0.851	0.149
Q50-Q56 Congenital malformations of genital organs	0.849	0.151
A09.9 Gastroenteritis and colitis of unspecified origin	0.849	0.151
J90-J94 Other diseases of pleura	0.848	0.152
H10-H13 Disorders of conjunctiva	0.846	0.154
D69 Purpura and other haemorrhagic conditions	0.845	0.155
A04 Other bacterial intestinal infections	0.845	0.155
E86 Volume depletion	0.844	0.156
J44.8 Other specified chronic obstructive pulmonary disease	0.844	0.156
S90-S99 Injuries to the ankle and foot	0.843	0.157
M65-M68 Disorders of synovium and tendon	0.843	0.157
E87.5 Hyperkalaemia	0.843	0.157
J03 Acute tonsillitis	0.842	0.158
Chapter V Mental and behavioural disorders	0.841	0.159
I50 Heart failure	0.840	0.160
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.840	0.160
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.840	0.160
E87.1 Hypo-osmolality and hyponatraemia	0.837	0.163
B90-B94 Sequelae of infectious and parasitic diseases	0.837	0.163
M80-M85 Disorders of bone density and structure	0.834	0.166
U88 Agent resistant to multiple antibiotics	0.833	0.167
N19 Unspecified renal failure	0.829	0.171
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.828	0.172
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.828	0.172
D69.6 Thrombocytopenia, unspecified	0.826	0.174
J80 Adult respiratory distress syndrome	0.826	0.174
E87.7 Fluid overload	0.823	0.177
A49.0 Staphylococcal infection, unspecified	0.821	0.179
M60-M63 Disorders of muscles	0.820	0.180
B37.3 Candidiasis of vulva and vagina	0.819	0.181
J14 Pneumonia due to Haemophilus influenzae	0.819	0.181
Y60-Y69 Misadventures to patients during surgical and medical care	0.818	0.182
S02 Fracture of skull and facial bones	0.817	0.183
I46 Cardiac arrest	0.816	0.184
I67.1 Cerebral aneurysm, nonruptured	0.815	0.185
M54 Dorsalgia	0.814	0.186
I38 Endocarditis, valve unspecified	0.812	0.188
M79 Other soft tissue disorders, not elsewhere classified	0.812	0.188
S40-S49 Injuries to the shoulder and upper arm	0.810	0.190
N70-N77 Inflammatory diseases of female pelvic organs	0.809	0.191
A04.7 Enterocolitis due to Clostridium difficile	0.807	0.193
A02 Other Salmonella infections	0.806	0.194
J03.9 Acute tonsillitis, unspecified	0.805	0.195
J44.9 Chronic obstructive pulmonary disease, unspecified	0.801	0.199
H93 Other disorders of ear, not elsewhere classified	0.799	0.201
M22 Disorders of patella	0.798	0.202
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.797	0.203
H91 Other hearing loss	0.791	0.209
I49 Other cardiac arrhythmias	0.791	0.209
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.791	0.209
B37.8 Candidiasis of other sites	0.791	0.209
N60-N64 Disorders of breast	0.790	0.210
B15-B19 Viral hepatitis	0.790	0.210
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.789	0.211
H11 Other disorders of conjunctiva	0.780	0.220
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.779	0.221
A80-A89 Viral infections of the central nervous system	0.777	0.222
J90 Pleural effusion, not elsewhere classified	0.777	0.223
J20-J22 Other acute lower respiratory infections	0.775	0.225
A39 Meningococcal infection	0.774	0.226
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.772	0.228
I69 Sequelae of cerebrovascular disease	0.770	0.230
M24 Other specific joint derangements	0.769	0.231
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.767	0.233
J11 Influenza, virus not identified	0.766	0.234
Q80-Q89 Other congenital malformations	0.766	0.234
J01 Acute sinusitis	0.765	0.235
N00-N08 Glomerular diseases	0.765	0.235
M77 Other enthesopathies	0.763	0.237
A50-A64 Infections with a predominantly sexual mode of transmission	0.761	0.239
U89 Agent resistant to other and unspecified antibiotics	0.761	0.239
Q51 Congenital malformations of uterus and cervix	0.759	0.241
T80 Complications following infusion, transfusion and therapeutic injection	0.758	0.242
D68 Other coagulation defects	0.756	0.244
J84.9 Interstitial pulmonary disease, unspecified	0.756	0.244
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.756	0.244
N62 Hypertrophy of breast	0.755	0.245
S92 Fracture of foot, except ankle	0.755	0.245
M89 Other disorders of bone	0.754	0.246
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.752	0.248
M80 Osteoporosis with pathological fracture	0.752	0.248
B35 Dermatophytosis	0.750	0.250
J15.9 Bacterial pneumonia, unspecified	0.749	0.251
H93.1 Tinnitus	0.749	0.251
I67.9 Cerebrovascular disease, unspecified	0.747	0.253
T79 Certain early complications of trauma, not elsewhere classified	0.746	0.254
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.746	0.254
M54.5 Low back pain	0.745	0.255
S10-S19 Injuries to the neck	0.743	0.257
I51 Complications and ill-defined descriptions of heart disease	0.743	0.257
T20-T25 Burns and corrosions of external body surface, specified by site	0.742	0.258
J10 Influenza due to identified influenza virus	0.742	0.258
V10-V19 Pedal cyclist injured in transport accident	0.742	0.258
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.742	0.258
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.741	0.259
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.741	0.259
I60.9 Subarachnoid haemorrhage, unspecified	0.740	0.260
M22.4 Chondromalacia patellae	0.739	0.261
M91-M94 Chondropathies	0.739	0.261
E00-E07 Disorders of thyroid gland	0.738	0.262
J42 Unspecified chronic bronchitis	0.738	0.262
I36 Nonrheumatic tricuspid valve disorders	0.737	0.263
H91.9 Hearing loss, unspecified	0.736	0.264
N17.0 Acute renal failure with tubular necrosis	0.736	0.264
I62 Other nontraumatic intracranial haemorrhage	0.735	0.265
I50.0 Congestive heart failure	0.735	0.265
N10-N16 Renal tubulo-interstitial diseases	0.734	0.266
S27.0 Traumatic pneumothorax	0.733	0.267
I67.8 Other specified cerebrovascular diseases	0.731	0.269
T15-T19 Effects of foreign body entering through natural orifice	0.731	0.269
S05 Injury of eye and orbit	0.728	0.272
S20 Superficial injury of thorax	0.728	0.272
S27.3 Other injuries of lung	0.727	0.273
X58-X59 Accidental exposure to other and unspecified factors	0.727	0.273
I10-I15 Hypertensive diseases	0.727	0.273
E87.0 Hyperosmolality and hypernatraemia	0.726	0.274
M31 Other necrotising vasculopathies	0.724	0.276
M65 Synovitis and tenosynovitis	0.724	0.276
E88 Other metabolic disorders	0.722	0.277
Y57 Other and unspecified drugs and medicaments	0.722	0.278
B65-B83 Helminthiases	0.722	0.278
F40-F48 Neurotic, stress-related and somatoform disorders	0.722	0.278
B91 Sequelae of poliomyelitis	0.720	0.280
E83 Disorders of mineral metabolism	0.719	0.281
I63 Cerebral infarction	0.718	0.281
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.718	0.282
B37.9 Candidiasis, unspecified	0.718	0.282
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.718	0.282
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
B99-B99 Other infectious diseases	0.717	0.283
B85-B89 Pediculosis, acariasis and other infestations	0.717	0.283
B50-B64 Protozoal diseases	0.717	0.283
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.717	0.283
A75-A79 Rickettsioses	0.717	0.283
A70-A74 Other diseases caused by chlamydiae	0.717	0.283
A65-A69 Other spirochaetal diseases	0.717	0.283
A20-A28 Certain zoonotic bacterial diseases	0.717	0.283
A15-A19 Tuberculosis	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.284
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.716	0.284
I00-I02 Acute rheumatic fever	0.716	0.284
I52 Other heart disorders in diseases classified elsewhere	0.715	0.285
I48 Atrial fibrillation and flutter	0.715	0.285
I43 Cardiomyopathy in diseases classified elsewhere	0.715	0.285
I41 Myocarditis in diseases classified elsewhere	0.715	0.285
I40 Acute myocarditis	0.715	0.285
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.715	0.285
I32 Pericarditis in diseases classified elsewhere	0.715	0.285
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
T00-T07 Injuries involving multiple body regions	0.715	0.285
E05 Thyrotoxicosis [hyperthyroidism]	0.715	0.285
M00-M03 Infectious arthropathies	0.715	0.285
A49.1 Streptococcal infection, unspecified	0.714	0.286
I42.8 Other cardiomyopathies	0.714	0.286
I42.7 Cardiomyopathy due to drugs and other external agents	0.714	0.286
I42.6 Alcoholic cardiomyopathy	0.714	0.286
I42.5 Other restrictive cardiomyopathy	0.714	0.286
I42.4 Endocardial fibroelastosis	0.714	0.286
I42.3 Endomyocardial (eosinophilic) disease	0.714	0.286
H60-H62 Diseases of external ear	0.713	0.287
T36-T50 Poisoning by drugs, medicaments and biological substances	0.713	0.287
Q20-Q28 Congenital malformations of the circulatory system	0.712	0.288
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.710	0.290
J17 Pneumonia in diseases classified elsewhere	0.709	0.291
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.709	0.291
J12 Viral pneumonia, not elsewhere classified	0.709	0.291
J09 Influenza due to certain identified influenza virus	0.709	0.291
M30 Polyarteritis nodosa and related conditions	0.707	0.293
S02.2 Fracture of nasal bones	0.707	0.293
J43 Emphysema	0.706	0.293
J15.2 Pneumonia due to staphylococcus	0.706	0.294
J95-J99 Other diseases of the respiratory system	0.705	0.295
I67.2 Cerebral atherosclerosis	0.704	0.295
I34 Nonrheumatic mitral valve disorders	0.704	0.296
M21 Other acquired deformities of limbs	0.704	0.296
I44.0 Atrioventricular block, first degree	0.703	0.297
M62 Other disorders of muscle	0.703	0.297
A07 Other protozoal intestinal diseases	0.702	0.298
A06 Amoebiasis	0.702	0.298
A05 Other bacterial foodborne intoxications	0.702	0.298
A03 Shigellosis	0.702	0.298
A01 Typhoid and paratyphoid fevers	0.702	0.298
A00 Cholera	0.702	0.298
I70-I79 Diseases of arteries, arterioles and capillaries	0.702	0.298
M54.3 Sciatica	0.702	0.298
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.701	0.299
W20-W49 Exposure to inanimate mechanical forces	0.701	0.299
H40-H42 Glaucoma	0.701	0.299
E89.0 Postprocedural hypothyroidism	0.700	0.300
S27.2 Traumatic heamopneumothorax	0.699	0.301
M79.6 Pain in limb	0.699	0.301
E05.9 Thyrotoxicosis, unspecified	0.698	0.302
I44.6 Other and unspecified fascicular block	0.696	0.304
I44.5 Left posterior fascicular block	0.696	0.304
I44.4 Left anterior fascicular block	0.696	0.304
H16 Keratitis	0.696	0.304
J82 Pulmonary eosinophilia, not elsewhere classified	0.695	0.305
A40 Streptococcal septicaemia	0.694	0.306
X60-X84 Intentional self-harm	0.694	0.306
I69.0 Sequelae of subarachnoid haemorrhage	0.694	0.306
I37 Pulmonary valve disorders	0.694	0.306
J13 Pneumonia due to Streptococcus pneumoniae	0.693	0.307
I85 Oesophageal varices	0.693	0.307
V40-V49 Car occupant injured in transport accident	0.692	0.308
M79.7 Fibromyalgia	0.692	0.308
H18 Other disorders of cornea	0.691	0.309
I50.1 Left ventricular failure	0.689	0.311
S80-S89 Injuries to the knee and lower leg	0.689	0.311
X40-X49 Accidental poisoning by and exposure to noxious substances	0.688	0.312
N64 Other disorders of breast	0.687	0.312
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.687	0.313
F40 Phobic anxiety disorders	0.686	0.313
Q38-Q45 Other congenital malformations of the digestive system	0.686	0.314
E87.3 Alkalosis	0.686	0.314
J84.8 Other specified interstitial pulmonary diseases	0.684	0.316
I31 Other diseases of pericardium	0.684	0.316
T83.3 Mechanical complication of intra-uterine contraceptive device	0.684	0.316
M70 Soft tissue disorders related to use, overuse and pressure	0.684	0.316
M80.9 Unspecified osteoporosis with pathological fracture	0.684	0.316
I68 Cerebrovascular disorders in diseases classified elsewhere	0.683	0.316
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.683	0.316
I49.0 Ventricular fibrillation and flutter	0.684	0.316
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.682	0.318
A02.0 Salmonella gastro-enteritis	0.682	0.318
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.681	0.319
B48 Other mycoses, not elsewhere classified	0.680	0.319
B47 Mycetoma	0.680	0.319
B46 Zygomycosis	0.680	0.319
B45 Cryptococcosis	0.680	0.319
B43 Chromomycosis and phaeomycotic abscess	0.680	0.319
B42 Sporotrichosis	0.680	0.319
B41 Paracoccidioidomycosis	0.680	0.319
B40 Blastomycosis	0.680	0.319
B39 Histoplasmosis	0.680	0.319
B38 Coccidioidomycosis	0.680	0.319
B36 Other superficial mycoses	0.680	0.319
B49 Unspecified mycosis	0.680	0.319
S06 Intracranial injury	0.680	0.320
I12 Hypertensive renal disease	0.680	0.320
H53-H54 Visual disturbances and blindness	0.679	0.321
J18.8 Other pneumonia, organism unspecified	0.679	0.321
J18.2 Hypostatic pneumonia, unspecified	0.679	0.321
T66-T78 Other and unspecified effects of external causes	0.679	0.321
I60.8 Other subarachnoid haemorrhage	0.679	0.321
N76 Other inflammation of vagina and vulva	0.678	0.322
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.678	0.322
E20-E35 Disorders of other endocrine glands	0.678	0.322
T79.6 Traumatic ischaemia of muscle	0.678	0.322
S29 Other and unspecified injuries of thorax	0.677	0.323
Y60.0 During surgical operation	0.677	0.323
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.676	0.323
Q35-Q37 Cleft lip and cleft palate	0.676	0.323
Q30-Q34 Congenital malformations of the respiratory system	0.676	0.323
Q00-Q07 Congenital malformations of the nervous system	0.676	0.323
I67.0 Dissection of cerebral arteries, nonruptured	0.676	0.324
T87 Complications peculiar to reattachment and amputation	0.676	0.324
S70-S79 Injuries to the hip and thigh	0.676	0.324
M90 Osteopathies in diseases classified elsewhere	0.676	0.324
A49.8 Other bacterial infections of unspecified site	0.676	0.324
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.675	0.325
J41 Simple and mucopurulent chronic bronchitis	0.675	0.325
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.674	0.326
I49.4 Other and unspecified premature depolarisation	0.674	0.326
B20-B24 Human immunodeficiency virus [HIV] disease	0.672	0.327
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.672	0.328
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.672	0.328
H17 Corneal scars and opacities	0.672	0.328
M79.65 Pain in limb (Pelvic region and thigh)	0.671	0.329
V80-V89 Other land transport accidents	0.670	0.330
X50-X57 Overexertion, travel and privation	0.670	0.330
I46.0 Cardiac arrest with successful resuscitation	0.668	0.332
H11.0 Pterygium	0.667	0.333
A48 Other bacterial diseases, not elsewhere classified	0.667	0.333
A44 Bartonellosis	0.667	0.333
A43 Nocardiosis	0.667	0.333
A42 Actinomycosis	0.667	0.333
A37 Whooping cough	0.667	0.333
A36 Diphtheria	0.667	0.333
A32 Listeriosis	0.667	0.333
A31 Infection due to other mycobacteria	0.667	0.333
A30 Leprosy [Hansen's disease]	0.667	0.333
A38 Scarlet fever	0.667	0.333
A35 Other tetanus	0.667	0.333
A34 Obstetrical tetanus	0.667	0.333
A33 Tetanus neonatorum	0.667	0.333
E85 Amyloidosis	0.667	0.333
E84 Cystic fibrosis	0.667	0.333
E79 Disorders of purine and pyrimidine metabolism	0.667	0.333
E77 Disorders of glycoprotein metabolism	0.667	0.333
E76 Disorders of glycosaminoglycan metabolism	0.667	0.333
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.667	0.333
E74 Other disorders of carbohydrate metabolism	0.667	0.333
E73 Lactose intolerance	0.667	0.333
E72 Other disorders of amino-acid metabolism	0.667	0.333
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.667	0.333
E70 Disorders of aromatic amino-acid metabolism	0.667	0.333
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.667	0.333
I30 Acute pericarditis	0.667	0.333
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.666	0.334
B07 Viral warts	0.666	0.334
J01.0 Acute maxillary sinusitis	0.665	0.335
D69.5 Secondary thrombocytopenia	0.664	0.336
H46-H48 Disorders of optic nerve and visual pathways	0.664	0.336
U89.8 Agent resistant to other single specified antibiotic	0.664	0.336
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.663	0.336
S26 Injury of heart	0.663	0.336
S25 Injury of blood vessels of thorax	0.663	0.336
S24 Injury of nerves and spinal cord at thorax level	0.663	0.336
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.663	0.336
S21 Open wound of thorax	0.663	0.336
J18.0 Bronchopneumonia, unspecified	0.662	0.338
M51 Other intervertebral disk disorders	0.662	0.338
S02.0 Fracture of vault of skull	0.662	0.338
A39.0 Meningococcal meningitis	0.662	0.338
H10 Conjunctivitis	0.661	0.338
F40.2 Specific (isolated) phobias	0.661	0.339
M79.2 Neuralgia and neuritis, unspecified	0.661	0.339
I44.1 Atrioventricular block, second degree	0.661	0.339
I33 Acute and subacute endocarditis	0.660	0.340
F30-F39 Mood [affective] disorders	0.659	0.341
Y35-Y36 Legal intervention and operations of war	0.659	0.341
Y10-Y34 Event of undetermined intent	0.659	0.341
Y00-Y09 Assault	0.659	0.341
X85-X99 Assault	0.659	0.341
X30-X39 Exposure to forces of nature	0.659	0.341
X10-X19 Contact with heat and hot substances	0.659	0.341
X00-X09 Exposure to smoke, fire and flames	0.659	0.341
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.659	0.341
W75-W84 Other accidental threats to breathing	0.659	0.341
W65-W74 Accidental drowning and submersion	0.659	0.341
W50-W64 Exposure to animate mechanical forces	0.659	0.341
V98-V99 Other and unspecified transport accidents	0.659	0.341
V95-V97 Air and space transport accidents	0.659	0.341
V90-V94 Water transport accidents	0.659	0.341
V70-V79 Bus occupant injured in transport accident	0.659	0.341
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.659	0.341
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.659	0.341
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.659	0.341
V01-V09 Pedestrian injured in transport accident	0.659	0.341
M31.3 Wegener's granulomatosis	0.658	0.342
N71 Inflammatory disease of uterus, except cervix	0.657	0.343
I85.9 Oesophageal varices without bleeding	0.657	0.343
J84.1 Other interstitial pulmonary diseases with fibrosis	0.657	0.343
T90 Sequelae of injuries of head	0.656	0.344
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.655	0.345
M24.8 Other specific joint derangements, not elsewhere classified	0.655	0.345
M22.2 Patellofemoral disorders	0.654	0.346
D69.3 Idiopathic thrombocytopenic purpura	0.654	0.346
N61 Inflammatory disorders of breast	0.653	0.347
I67.7 Cerebral arteritis, not elsewhere classified	0.653	0.347
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.653	0.347
I67.5 Moyamoya disease	0.653	0.347
I67.4 Hypertensive encephalopathy	0.653	0.347
I67.3 Progressive vascular leukoencephalopathy	0.653	0.347
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.653	0.347
E87.4 Mixed disorder of acid-base balance	0.652	0.348
B00 Herpesviral [herpes simplex] infections	0.652	0.348
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.651	0.349
Y41 Other systemic anti-infectives and antiparasitics	0.651	0.349
M77.1 Lateral epicondylitis	0.650	0.350
M89.8 Other specified disorders of bone	0.650	0.350
B37.7 Candidal septicaemia	0.649	0.351
B37.6 Candidal endocarditis	0.649	0.351
B37.5 Candidal meningitis	0.649	0.351
B37.4 Candidiasis of other urogenital sites	0.649	0.351
B37.2 Candidiasis of skin and nail	0.649	0.351
B37.1 Pulmonary candidiasis	0.649	0.351
A49.9 Bacterial infection, unspecified	0.649	0.351
M54.59 Low back pain (Site unspecified)	0.649	0.351
M53 Other dorsopathies, not elsewhere classified	0.649	0.351
B44 Aspergillosis	0.647	0.353
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.646	0.354
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.646	0.354
M87 Osteonecrosis	0.646	0.354
J60-J70 Lung diseases due to external agents	0.646	0.354
H11.3 Conjunctival haemorrhage	0.645	0.355
H65-H75 Diseases of middle ear and mastoid	0.644	0.356
T84.3 Mechanical complication of other bone devices, implants and grafts	0.644	0.356
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.644	0.356
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.644	0.356
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.644	0.356
M77.0 Medial epicondylitis	0.643	0.357
X20-X29 Contact with venomous animals and plants	0.643	0.357
U84 Resistance to other antimicrobial drugs	0.643	0.357
U83 Resistance to other antibiotics	0.643	0.357
U82 Resistance to betalactam antibiotics	0.643	0.357
U85 Resistance to antineoplastic drugs	0.643	0.357
T85 Complications of other internal prosthetic devices, implants and grafts	0.642	0.357
S02.8 Fractures of other skull and facial bones	0.642	0.358
I86 Varicose veins of other sites	0.642	0.358
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.641	0.359
J94 Other pleural conditions	0.641	0.359
I12.0 Hypertensive renal disease with renal failure	0.641	0.359
S31 Open wound of abdomen, lower back and pelvis	0.640	0.359
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.640	0.360
S02.4 Fracture of malar and maxillary bones	0.639	0.361
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.639	0.361
J15.0 Pneumonia due to Klebsiella pneumoniae	0.637	0.363
M79.8 Other specified soft tissue disorders	0.637	0.363
M79.9 Soft tissue disorder, unspecified	0.636	0.363
M24.1 Other articular cartilage disorders	0.636	0.364
H55-H59 Other disorders of eye and adnexa	0.635	0.365
N17.8 Other acute renal failure	0.635	0.365
N17.2 Acute renal failure with medullary necrosis	0.635	0.365
N17.1 Acute renal failure with acute cortical necrosis	0.635	0.365
S22 Fracture of rib(s), sternum and thoracic spine	0.634	0.365
I44.3 Other and unspecified atrioventricular block	0.634	0.366
A49.3 Mycoplasma infection, unspecified	0.634	0.366
A49.2 Haemophilus influenzae infection, unspecified	0.634	0.366
M79.4 Hypertrophy of (infrapatellar) fat pad	0.634	0.366
B18 Chronic viral hepatitis	0.633	0.367
S90 Superficial injury of ankle and foot	0.633	0.367
Chapter VI Diseases of the nervous system	0.633	0.367
Y52 Agents primarily affecting the cardiovascular system	0.632	0.368
M76 Enthesopathies of lower limb, excluding foot	0.632	0.368
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.632	0.368
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.631	0.369
S02.5 Fracture of tooth	0.630	0.370
S37 Injury of urinary and pelvic organs	0.630	0.370
I51.7 Cardiomegaly	0.630	0.370
T80.2 Infections following infusion, transfusion and therapeutic injection	0.629	0.371
N10 Acute tubulo-interstitial nephritis	0.629	0.371
J02 Acute pharyngitis	0.629	0.371
Q54 Hypospadias	0.628	0.372
S02.20 Fracture of nasal bones (closed)	0.627	0.373
N18 Chronic renal failure	0.627	0.373
M67 Other disorders of synovium and tendon	0.627	0.373
Q78 Other osteochondrodysplasias	0.625	0.375
B37.0 Candidal stomatitis	0.625	0.375
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.624	0.375
N75 Diseases of Bartholin's gland	0.624	0.375
J15.8 Other bacterial pneumonia	0.624	0.376
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.624	0.376

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations