TreeWAS – Variant ID: rs12602637

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter V Mental and behavioural disorders	1.000	0.000
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001
Chapter I Certain infectious and parasitic diseases	0.998	0.002
F30-F39 Mood [affective] disorders	0.998	0.002
Chapter IV Endocrine, nutritional and metabolic diseases	0.997	0.003
B95-B98 Bacterial, viral and other infectious agents	0.995	0.005
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.994	0.006
T36-T50 Poisoning by drugs, medicaments and biological substances	0.994	0.006
S50-S59 Injuries to the elbow and forearm	0.993	0.007
M05-M14 Inflammatory polyarthropathies	0.993	0.007
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.993	0.007
F00-F09 Organic, including symptomatic, mental disorders	0.991	0.009
S52 Fracture of forearm	0.990	0.010
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.990	0.010
A00-A09 Intestinal infectious diseases	0.990	0.010
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.987	0.013
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.984	0.016
E16 Other disorders of pancreatic internal secretion	0.980	0.020
F31 Bipolar affective disorder	0.979	0.021
M13 Other arthritis	0.977	0.023
A09.9 Gastroenteritis and colitis of unspecified origin	0.977	0.023
E16.2 Hypoglycaemia, unspecified	0.974	0.026
Chapter VIII Diseases of the ear and mastoid process	0.974	0.026
M70-M79 Other soft tissue disorders	0.970	0.030
F03 Unspecified dementia	0.968	0.032
F20 Schizophrenia	0.967	0.033
M13.9 Arthritis, unspecified	0.964	0.036
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.962	0.038
S52.0 Fracture of upper end of ulna	0.961	0.039
M79 Other soft tissue disorders, not elsewhere classified	0.960	0.040
Chapter VI Diseases of the nervous system	0.956	0.044
F33 Recurrent depressive disorder	0.956	0.044
M13.97 Arthritis, unspecified (Ankle and foot)	0.955	0.045
S52.6 Fracture of lower end of both ulna and radius	0.948	0.052
M79.6 Pain in limb	0.946	0.054
S52.00 Fracture of upper end of ulna (closed)	0.945	0.055
F20.9 Schizophrenia, unspecified	0.936	0.064
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.935	0.065
H65-H75 Diseases of middle ear and mastoid	0.935	0.065
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.925	0.075
E10-E14 Diabetes mellitus	0.921	0.079
S52.60 Fracture of lower end of both ulna and radius (closed)	0.918	0.082
S90-S99 Injuries to the ankle and foot	0.912	0.088
F10 Mental and behavioural disorders due to use of alcohol	0.911	0.089
T15-T19 Effects of foreign body entering through natural orifice	0.904	0.096
M79.60 Pain in limb (Multiple sites)	0.899	0.101
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.898	0.102
G30-G32 Other degenerative diseases of the nervous system	0.896	0.104
T46 Poisoning by agents primarily affecting the cardiovascular system	0.895	0.105
M10 Gout	0.893	0.107
M65-M68 Disorders of synovium and tendon	0.891	0.109
G90-G99 Other disorders of the nervous system	0.891	0.109
M79.7 Fibromyalgia	0.891	0.109
M79.65 Pain in limb (Pelvic region and thigh)	0.890	0.110
H72 Perforation of tympanic membrane	0.886	0.114
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.885	0.115
H74 Other disorders of middle ear and mastoid	0.884	0.116
E10 Insulin-dependent diabetes mellitus	0.881	0.119
S52.1 Fracture of upper end of radius	0.869	0.131
G00-G09 Inflammatory diseases of the central nervous system	0.868	0.132
F33.9 Recurrent depressive disorder, unspecified	0.868	0.132
Q20-Q28 Congenital malformations of the circulatory system	0.865	0.135
F10.0 Acute intoxication	0.863	0.137
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.862	0.138
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.861	0.139
E50-E64 Other nutritional deficiencies	0.860	0.140
F29 Unspecified nonorganic psychosis	0.854	0.146
M86-M90 Other osteopathies	0.852	0.148
M13.90 Arthritis, unspecified (Multiple sites)	0.851	0.149
M65 Synovitis and tenosynovitis	0.843	0.157
F31.6 Bipolar affective disorder, current episode mixed	0.843	0.157
E20-E35 Disorders of other endocrine glands	0.841	0.159
M13.96 Arthritis, unspecified (Lower leg)	0.839	0.161
M79.79 Fibromyalgia (Site unspecified)	0.838	0.162
S92 Fracture of foot, except ankle	0.837	0.163
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.836	0.164
S52.7 Multiple fractures of forearm	0.833	0.167
A02 Other Salmonella infections	0.832	0.168
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.826	0.174
F20.0 Paranoid schizophrenia	0.825	0.175
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.824	0.176
M10.9 Gout, unspecified	0.822	0.178
F32 Depressive episode	0.821	0.179
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.819	0.181
F10.2 Dependence syndrome	0.819	0.181
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.817	0.183
B97 Viral agents as the cause of diseases classified to other chapters	0.816	0.184
F00 Dementia in Alzheimer's disease	0.815	0.185
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.814	0.186
H65 Nonsuppurative otitis media	0.810	0.190
M05 Seropositive rheumatoid arthritis	0.810	0.190
F25 Schizoaffective disorders	0.808	0.192
S70-S79 Injuries to the hip and thigh	0.807	0.193
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.807	0.193
M71 Other bursopathies	0.801	0.199
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.801	0.199
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.800	0.200
E10.3 With ophthalmic complications	0.800	0.200
H72.9 Perforation of tympanic membrane, unspecified	0.798	0.202
Q24 Other congenital malformations of heart	0.796	0.204
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.794	0.206
E10.9 Without complications	0.794	0.206
M79.69 Pain in limb (Site unspecified)	0.794	0.206
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.794	0.206
M50-M54 Other dorsopathies	0.792	0.208
F33.1 Recurrent depressive disorder, current episode moderate	0.791	0.209
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.791	0.209
M60-M63 Disorders of muscles	0.790	0.210
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.790	0.210
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.790	0.210
S92.0 Fracture of calcaneus	0.787	0.213
G31.9 Degenerative disease of nervous system, unspecified	0.786	0.214
H60-H62 Diseases of external ear	0.786	0.214
M00-M03 Infectious arthropathies	0.784	0.216
S52.10 Fracture of upper end of radius (closed)	0.783	0.217
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.781	0.218
F80-F89 Disorders of psychological development	0.781	0.219
M91-M94 Chondropathies	0.781	0.219
M79.9 Soft tissue disorder, unspecified	0.778	0.222
A80-A89 Viral infections of the central nervous system	0.777	0.223
T79-T79 Certain early complications of trauma	0.777	0.223
F02 Dementia in other diseases classified elsewhere	0.776	0.224
B90-B94 Sequelae of infectious and parasitic diseases	0.774	0.226
S56 Injury of muscle and tendon at forearm level	0.774	0.226
H90-H95 Other disorders of ear	0.772	0.228
T39.0 Salicylates	0.770	0.230
T39.1 4-Aminophenol derivatives	0.768	0.232
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.768	0.232
F39 Unspecified mood [affective] disorder	0.767	0.233
T17 Foreign body in respiratory tract	0.767	0.233
G04 Encephalitis, myelitis and encephalomyelitis	0.766	0.234
S20-S29 Injuries to the thorax	0.760	0.240
T20-T25 Burns and corrosions of external body surface, specified by site	0.759	0.241
E70-E90 Metabolic disorders	0.754	0.246
T16 Foreign body in ear	0.754	0.246
M06 Other rheumatoid arthritis	0.753	0.247
M65.8 Other synovitis and tenosynovitis	0.752	0.248
S92.00 Fracture of calcaneus (closed)	0.752	0.248
F05 Delirium, not induced by alcohol and other psychoactive substances	0.752	0.248
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.751	0.249
M10.99 Gout, unspecified (Site unspecified)	0.751	0.249
M79.61 Pain in limb (Shoulder region)	0.750	0.250
S52.3 Fracture of shaft of radius	0.749	0.251
G80-G83 Cerebral palsy and other paralytic syndromes	0.749	0.251
F10.1 Harmful use	0.749	0.251
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.748	0.252
F33.0 Recurrent depressive disorder, current episode mild	0.747	0.253
M79.68 Pain in limb (Other)	0.747	0.253
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.746	0.254
M86 Osteomyelitis	0.744	0.256
F31.0 Bipolar affective disorder, current episode hypomanic	0.742	0.258
G93 Other disorders of brain	0.741	0.259
Q24.9 Congenital malformation of the heart, unspecified	0.740	0.260
F22 Persistent delusional disorders	0.739	0.261
F01 Vascular dementia	0.739	0.261
S40-S49 Injuries to the shoulder and upper arm	0.738	0.262
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.737	0.263
T46.4 Angiotensin-converting-enzyme inhibitors	0.737	0.263
B99-B99 Other infectious diseases	0.735	0.265
M79.5 Residual foreign body in soft tissue	0.734	0.266
F30 Manic episode	0.731	0.268
H74.0 Tympanosclerosis	0.731	0.269
G97.1 Other reaction to spinal and lumbar puncture	0.731	0.269
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.731	0.269
H74.9 Disorder of middle ear and mastoid, unspecified	0.731	0.269
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.731	0.269
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.730	0.269
M13.8 Other specified arthritis	0.730	0.269
M79.62 Pain in limb (Upper arm)	0.728	0.272
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.727	0.273
F10.5 Psychotic disorder	0.727	0.273
H65.9 Nonsuppurative otitis media, unspecified	0.724	0.276
M40-M43 Deforming dorsopathies	0.723	0.276
G20-G26 Extrapyramidal and movement disorders	0.723	0.277
S52.4 Fracture of shafts of both ulna and radius	0.723	0.277
F10.6 Amnesic syndrome	0.723	0.277
H74.1 Adhesive middle ear disease	0.722	0.278
S52.70 Multiple fractures of forearm (closed)	0.721	0.279
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.721	0.279
M79.63 Pain in limb (Forearm)	0.721	0.279
T00-T07 Injuries involving multiple body regions	0.720	0.280
E16.1 Other hypoglycaemia	0.720	0.280
S71 Open wound of hip and thigh	0.719	0.281
A02.0 Salmonella gastro-enteritis	0.719	0.281
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.718	0.282
Q21 Congenital malformations of cardiac septa	0.717	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.717	0.283
F70-F79 Mental retardation	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.716	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.283
Q38-Q45 Other congenital malformations of the digestive system	0.716	0.284
B85-B89 Pediculosis, acariasis and other infestations	0.715	0.284
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.715	0.284
A75-A79 Rickettsioses	0.715	0.284
A70-A74 Other diseases caused by chlamydiae	0.715	0.284
A65-A69 Other spirochaetal diseases	0.715	0.284
A20-A28 Certain zoonotic bacterial diseases	0.715	0.284
A15-A19 Tuberculosis	0.715	0.284
F38 Other mood [affective] disorders	0.715	0.284
H74.3 Other acquired abnormalities of ear ossicles	0.714	0.286
B50-B64 Protozoal diseases	0.714	0.286
M13.91 Arthritis, unspecified (Shoulder region)	0.714	0.286
M80-M85 Disorders of bone density and structure	0.714	0.286
G70-G73 Diseases of myoneural junction and muscle	0.713	0.287
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.713	0.287
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.713	0.287
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.713	0.287
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.713	0.287
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.713	0.287
T41 Poisoning by anaesthetics and therapeutic gases	0.713	0.287
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.713	0.287
T36 Poisoning by systemic antibiotics	0.713	0.287
G30 Alzheimer's disease	0.713	0.287
S58 Traumatic amputation of forearm	0.712	0.288
S57 Crushing injury of forearm	0.712	0.288
S55 Injury of blood vessels at forearm level	0.712	0.288
S54 Injury of nerves at forearm level	0.712	0.288
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.712	0.288
E34 Other endocrine disorders	0.712	0.288
M12 Other specific arthropathies	0.712	0.288
M09 Juvenile arthritis in diseases classified elsewhere	0.712	0.288
M08 Juvenile arthritis	0.712	0.288
H60 Otitis externa	0.711	0.289
S59 Other and unspecified injuries of forearm	0.711	0.289
M65.9 Synovitis and tenosynovitis, unspecified	0.711	0.289
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.711	0.289
F09 Unspecified organic or symptomatic mental disorder	0.711	0.289
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.711	0.289
S50 Superficial injury of forearm	0.711	0.289
S52.9 Fracture of forearm, part unspecified	0.710	0.290
F28 Other nonorganic psychotic disorders	0.710	0.290
F24 Induced delusional disorder	0.710	0.290
F21 Schizotypal disorder	0.710	0.290
A06 Amoebiasis	0.710	0.290
A05 Other bacterial foodborne intoxications	0.710	0.290
A03 Shigellosis	0.710	0.290
A01 Typhoid and paratyphoid fevers	0.710	0.290
A00 Cholera	0.710	0.290
M11 Other crystal arthropathies	0.709	0.291
M76 Enthesopathies of lower limb, excluding foot	0.709	0.291
H72.1 Attic perforation of tympanic membrane	0.709	0.291
H80-H83 Diseases of inner ear	0.708	0.292
E15 Nondiabetic hypoglycaemic coma	0.707	0.292
T38.1 Thyroid hormones and substitutes	0.707	0.293
E53 Deficiency of other B group vitamins	0.707	0.293
G91 Hydrocephalus	0.706	0.294
M13.0 Polyarthritis, unspecified	0.705	0.295
M13.92 Arthritis, unspecified (Upper arm)	0.705	0.295
H74.8 Other specified disorders of middle ear and mastoid	0.704	0.296
E55 Vitamin D deficiency	0.704	0.296
T42.4 Benzodiazepines	0.703	0.297
E16.9 Disorder of pancreatic internal secretion, unspecified	0.702	0.298
E16.8 Other specified disorders of pancreatic internal secretion	0.702	0.298
E16.4 Abnormal secretion of gastrin	0.702	0.298
E16.3 Increased secretion of glucagon	0.702	0.298
E16.0 Drug-induced hypoglycaemia without coma	0.702	0.298
Q00-Q07 Congenital malformations of the nervous system	0.702	0.298
A50-A64 Infections with a predominantly sexual mode of transmission	0.702	0.298
F31.8 Other bipolar affective disorders	0.702	0.298
F31.7 Bipolar affective disorder, currently in remission	0.702	0.298
A07 Other protozoal intestinal diseases	0.701	0.299
M13.1 Monoarthritis, not elsewhere classified	0.701	0.299
M79.4 Hypertrophy of (infrapatellar) fat pad	0.700	0.300
S52.8 Fracture of other parts of forearm	0.700	0.300
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.700	0.300
F32.2 Severe depressive episode without psychotic symptoms	0.698	0.302
F32.0 Mild depressive episode	0.697	0.303
F99-F99 Unspecified mental disorder	0.696	0.304
G98 Other disorders of nervous system, not elsewhere classified	0.696	0.304
M73 Soft tissue disorders in diseases classified elsewhere	0.695	0.304
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.695	0.305
M72 Fibroblastic disorders	0.694	0.306
F20.8 Other schizophrenia	0.694	0.306
F20.6 Simple schizophrenia	0.694	0.306
F20.5 Residual schizophrenia	0.694	0.306
F20.4 Postschizophrenic depression	0.694	0.306
F20.3 Undifferentiated schizophrenia	0.694	0.306
F20.2 Catatonic schizophrenia	0.694	0.306
F20.1 Hebephrenic schizophrenia	0.694	0.306
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.690	0.310
T39.4 Antirheumatics, not elsewhere classified	0.690	0.310
T39.2 Pyrazolone derivatives	0.690	0.310
F34 Persistent mood [affective] disorders	0.689	0.311
M79.3 Panniculitis, unspecified	0.688	0.311
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.686	0.313
H72.8 Other perforations of tympanic membrane	0.686	0.314
M77 Other enthesopathies	0.686	0.314
Q60-Q64 Congenital malformations of the urinary system	0.686	0.314
M13.94 Arthritis, unspecified (Hand)	0.686	0.314
T18 Foreign body in alimentary tract	0.685	0.315
F33.8 Other recurrent depressive disorders	0.685	0.315
F33.4 Recurrent depressive disorder, currently in remission	0.685	0.315
G93.4 Encephalopathy, unspecified	0.685	0.315
S90 Superficial injury of ankle and foot	0.684	0.316
F23 Acute and transient psychotic disorders	0.683	0.316
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.683	0.317
H65.2 Chronic serous otitis media	0.683	0.317
S52.61 Fracture of lower end of both ulna and radius (open)	0.680	0.320
M05.9 Seropositive rheumatoid arthritis, unspecified	0.679	0.321
M89 Other disorders of bone	0.679	0.321
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.679	0.321
M54 Dorsalgia	0.678	0.322
H72.0 Central perforation of tympanic membrane	0.678	0.322
F60-F69 Disorders of adult personality and behaviour	0.677	0.323
G31.0 Circumscribed brain atrophy	0.677	0.323
M14 Arthropathies in other diseases classified elsewhere	0.677	0.323
G96 Other disorders of central nervous system	0.676	0.324
M13.93 Arthritis, unspecified (Forearm)	0.676	0.324
E10.4 With neurological complications	0.672	0.328
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.672	0.328
F18 Mental and behavioural disorders due to use of volatile solvents	0.671	0.329
F16 Mental and behavioural disorders due to use of hallucinogens	0.671	0.329
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.671	0.329
F14 Mental and behavioural disorders due to use of cocaine	0.671	0.329
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.671	0.329
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.671	0.329
H68 Eustachian salpingitis and obstruction	0.671	0.329
H67 Otitis media in diseases classified elsewhere	0.671	0.329
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.670	0.330
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.670	0.330
G90 Disorders of autonomic nervous system	0.670	0.330
H72.2 Other marginal perforations of tympanic membrane	0.670	0.330
F12 Mental and behavioural disorders due to use of cannabinoids	0.668	0.331
E26 Hyperaldosteronism	0.668	0.332
M66 Spontaneous rupture of synovium and tendon	0.666	0.333
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.666	0.334
E10.5 With peripheral circulatory complications	0.666	0.334
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.664	0.336
B15-B19 Viral hepatitis	0.664	0.336
A08 Viral and other specified intestinal infections	0.663	0.337
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.663	0.337
Q35-Q37 Cleft lip and cleft palate	0.663	0.337
Q30-Q34 Congenital malformations of the respiratory system	0.663	0.337
E10.0 With coma	0.662	0.338
G97.8 Other postprocedural disorders of nervous system	0.662	0.338
M07 Psoriatic and enteropathic arthropathies	0.661	0.339
E12 Malnutrition-related diabetes mellitus	0.660	0.339
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.660	0.340
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.659	0.341
S52.2 Fracture of shaft of ulna	0.659	0.341
M71.3 Other bursal cyst	0.658	0.341
F81 Specific developmental disorders of scholastic skills	0.657	0.342
S91 Open wound of ankle and foot	0.657	0.342
M79.1 Myalgia	0.657	0.343
F11 Mental and behavioural disorders due to use of opioids	0.657	0.343
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.656	0.344
M10.92 Gout, unspecified (Upper arm)	0.656	0.344
G01 Meningitis in bacterial diseases classified elsewhere	0.655	0.345
M65.4 Radial styloid tenosynovitis [de Quervain]	0.655	0.345
M79.70 Fibromyalgia (Multiple sites)	0.655	0.345
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.654	0.346
B65-B83 Helminthiases	0.654	0.346
S98 Traumatic amputation of ankle and foot	0.654	0.346
S97 Crushing injury of ankle and foot	0.654	0.346
S96 Injury of muscle and tendon at ankle and foot level	0.654	0.346
S95 Injury of blood vessels at ankle and foot level	0.654	0.346
S94 Injury of nerves at ankle and foot level	0.654	0.346
F10.9 Unspecified mental and behavioural disorder	0.653	0.346
F10.8 Other mental and behavioural disorders	0.653	0.346
F10.7 Residual and late-onset psychotic disorder	0.653	0.346
M70 Soft tissue disorders related to use, overuse and pressure	0.653	0.346
M79.64 Pain in limb (Hand)	0.652	0.348
E11 Non-insulin-dependent diabetes mellitus	0.651	0.349
Q80-Q89 Other congenital malformations	0.651	0.349
S92.2 Fracture of other tarsal bone(s)	0.650	0.349
E40-E46 Malnutrition	0.650	0.350
M65.1 Other infective (teno)synovitis	0.648	0.352
T19 Foreign body in genito-urinary tract	0.648	0.352
T15 Foreign body on external eye	0.648	0.352
F06.7 Mild cognitive disorder	0.647	0.353
S92.4 Fracture of great toe	0.647	0.353
M79.96 Soft tissue disorder, unspecified (Lower leg)	0.647	0.353
M94 Other disorders of cartilage	0.646	0.354
Q50-Q56 Congenital malformations of genital organs	0.646	0.354
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.645	0.355
T38.9 Other and unspecified hormone antagonists	0.644	0.356
T38.8 Other and unspecified hormones and their synthetic substitutes	0.644	0.356
T38.7 Androgens and anabolic congeners	0.644	0.356
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.644	0.356
T38.5 Other oestrogens and progestogens	0.644	0.356
T38.4 Oral contraceptives	0.644	0.356
T38.2 Antithyroid drugs	0.644	0.356
T38.0 Glucocorticoids and synthetic analogues	0.644	0.356
F25.9 Schizoaffective disorder, unspecified	0.642	0.357
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.642	0.358
M79.2 Neuralgia and neuritis, unspecified	0.642	0.358
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.641	0.358
T46.8 Antivaricose drugs, including sclerosing agents	0.641	0.358
T46.7 Peripheral vasodilators	0.641	0.358
T46.5 Other antihypertensive drugs, not elsewhere classified	0.641	0.358
T46.3 Coronary vasodilators, not elsewhere classified	0.641	0.358
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.641	0.358
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.641	0.358
M87 Osteonecrosis	0.642	0.358
Q23 Congenital malformations of aortic and mitral valves	0.642	0.358
E20 Hypoparathyroidism	0.641	0.359
H70 Mastoiditis and related conditions	0.641	0.359
F32.8 Other depressive episodes	0.641	0.359
M45-M49 Spondylopathies	0.641	0.359
M62 Other disorders of muscle	0.641	0.359
M10.4 Other secondary gout	0.640	0.359
M10.3 Gout due to impairment of renal function	0.640	0.359
M10.2 Drug-induced gout	0.640	0.359
M10.1 Lead-induced gout	0.640	0.359
M10.0 Idiopathic gout	0.640	0.359
H93 Other disorders of ear, not elsewhere classified	0.640	0.360
T46.1 Calcium-channel blockers	0.640	0.360
H69 Other disorders of Eustachian tube	0.639	0.361
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.639	0.361
G94 Other disorders of brain in diseases classified elsewhere	0.639	0.361
G92 Toxic encephalopathy	0.639	0.361
F32.1 Moderate depressive episode	0.639	0.361
M79.78 Fibromyalgia (Other)	0.639	0.361
M79.77 Fibromyalgia (Ankle and foot)	0.639	0.361
M79.76 Fibromyalgia (Lower leg)	0.639	0.361
M79.75 Fibromyalgia (Pelvic region and thigh)	0.639	0.361
M79.74 Fibromyalgia (Hand)	0.639	0.361
M79.73 Fibromyalgia (Forearm)	0.639	0.361
M79.72 Fibromyalgia (Upper arm)	0.639	0.361
M79.71 Fibromyalgia (Shoulder region)	0.639	0.361
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.638	0.362
G03 Meningitis due to other and unspecified causes	0.637	0.363
S41 Open wound of shoulder and upper arm	0.636	0.364
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.636	0.364
B20-B24 Human immunodeficiency virus [HIV] disease	0.635	0.365
E14 Unspecified diabetes mellitus	0.634	0.366
H74.2 Discontinuity and dislocation of ear ossicles	0.634	0.366
G00 Bacterial meningitis, not elsewhere classified	0.633	0.367
M10.93 Gout, unspecified (Forearm)	0.633	0.367
H81 Disorders of vestibular function	0.632	0.368
E10.8 With unspecified complications	0.631	0.368
E10.7 With multiple complications	0.631	0.368
E10.6 With other specified complications	0.631	0.368
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.631	0.369
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.630	0.370
M06.3 Rheumatoid nodule	0.630	0.370
F02.0 Dementia in Pick's disease	0.629	0.371
M00 Pyogenic arthritis	0.629	0.371
F25.1 Schizoaffective disorder, depressive type	0.628	0.372
G31.2 Degeneration of nervous system due to alcohol	0.627	0.373
H92 Otalgia and effusion of ear	0.627	0.373
H65.0 Acute serous otitis media	0.625	0.375
S52.11 Fracture of upper end of radius (open)	0.623	0.377
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.622	0.377
G09 Sequelae of inflammatory diseases of central nervous system	0.622	0.377
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.622	0.377
S52.01 Fracture of upper end of ulna (open)	0.622	0.377
E23 Hypofunction and other disorders of pituitary gland	0.622	0.378
S27 Injury of other and unspecified intrathoracic organs	0.621	0.379
Q26 Congenital malformations of great veins	0.620	0.380
Q25 Congenital malformations of great arteries	0.620	0.380
Q22 Congenital malformations of pulmonary and tricuspid valves	0.620	0.380
Q20 Congenital malformations of cardiac chambers and connexions	0.620	0.380
E88 Other metabolic disorders	0.620	0.380
E61 Deficiency of other nutrient elements	0.620	0.380
H60.5 Acute otitis externa, non-infective	0.619	0.381
T79 Certain early complications of trauma, not elsewhere classified	0.618	0.382
E64 Sequelae of malnutrition and other nutritional deficiencies	0.617	0.383
E63 Other nutritional deficiencies	0.617	0.383
E56 Other vitamin deficiencies	0.617	0.383
E51 Thiamine deficiency	0.617	0.383
E50 Vitamin A deficiency	0.617	0.383
E60 Dietary zinc deficiency	0.617	0.383
E59 Dietary selenium deficiency	0.617	0.383
E58 Dietary calcium deficiency	0.617	0.383
E54 Ascorbic acid deficiency	0.617	0.383
E52 Niacin deficiency [pellagra]	0.617	0.383
G83 Other paralytic syndromes	0.617	0.383
E13 Other specified diabetes mellitus	0.617	0.383
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.616	0.384
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.615	0.385
S71.0 Open wound of hip	0.615	0.385
M71.1 Other infective bursitis	0.614	0.385
M54.9 Dorsalgia, unspecified	0.614	0.385
F00.0 Dementia in Alzheimer's disease with early onset	0.614	0.386
G63 Polyneuropathy in diseases classified elsewhere	0.614	0.386
B91 Sequelae of poliomyelitis	0.614	0.386
E24 Cushing's syndrome	0.612	0.388
F19.1 Harmful use	0.611	0.389
S92.7 Multiple fractures of foot	0.610	0.390
E87 Other disorders of fluid, electrolyte and acid-base balance	0.610	0.390
S70 Superficial injury of hip and thigh	0.609	0.391
G06 Intracranial and intraspinal abscess and granuloma	0.609	0.391
T11 Other injuries of upper limb, level unspecified	0.609	0.391
T17.5 Foreign body in bronchus	0.609	0.391
E10.2 With renal complications	0.607	0.393
M86.9 Osteomyelitis, unspecified	0.606	0.394
E85 Amyloidosis	0.606	0.394
M92 Other juvenile osteochondrosis	0.606	0.394
Q27 Other congenital malformations of peripheral vascular system	0.606	0.394
M10.97 Gout, unspecified (Ankle and foot)	0.606	0.394
M79.0 Rheumatism, unspecified	0.606	0.394
Q28 Other congenital malformations of circulatory system	0.605	0.395
M65.2 Calcific tendinitis	0.604	0.395
M65.0 Abscess of tendon sheath	0.604	0.395
E89.0 Postprocedural hypothyroidism	0.604	0.396
E35 Disorders of endocrine glands in diseases classified elsewhere	0.603	0.397

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations