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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12660335
log Bayes Factor = 12.2121
Chromosome 6   position 42,454,761  (GRCh37) Explore rs12660335 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
I45 Other conduction disorders
0.994 0.006 0.000
I45.1 Other and unspecified right bundle-branch block
0.990 0.010 0.000
I44 Atrioventricular and left bundle-branch block
0.988 0.012 0.000
I20-I25 Ischaemic heart diseases
0.979 0.021 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.978 0.022 0.000
H40-H42 Glaucoma
0.975 0.025 0.000
Chapter VIII Diseases of the ear and mastoid process
0.974 0.026 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.971 0.029 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.969 0.031 0.000
I44.7 Left bundle-branch block, unspecified
0.967 0.033 0.000
I50 Heart failure
0.967 0.033 0.000
I47 Paroxysmal tachycardia
0.966 0.034 0.000
H40 Glaucoma
0.957 0.043 0.000
I42 Cardiomyopathy
0.955 0.045 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.952 0.048 0.000
Chapter I Certain infectious and parasitic diseases
0.949 0.051 0.000
H65-H75 Diseases of middle ear and mastoid
0.947 0.053 0.000
O80-O84 Delivery
0.941 0.058 0.000
Chapter VI Diseases of the nervous system
0.940 0.060 0.000
I20 Angina pectoris
0.938 0.062 0.000
H40.9 Glaucoma, unspecified
0.936 0.064 0.000
E10-E14 Diabetes mellitus
0.935 0.065 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.933 0.067 0.000
I50.1 Left ventricular failure
0.924 0.076 0.000
O00-O08 Pregnancy with abortive outcome
0.920 0.080 0.000
I20.9 Angina pectoris, unspecified
0.920 0.080 0.000
E10 Insulin-dependent diabetes mellitus
0.920 0.080 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.920 0.080 0.000
O80 Single spontaneous delivery
0.918 0.082 0.000
H25-H28 Disorders of lens
0.917 0.083 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.912 0.088 0.000
H43-H45 Disorders of vitreous body and globe
0.907 0.093 0.000
I42.0 Dilated cardiomyopathy
0.906 0.094 0.000
O04 Medical abortion
0.905 0.095 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.896 0.104 0.000
O04.9 Complete or unspecified, without complication
0.895 0.105 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.894 0.106 0.000
E65-E68 Obesity and other hyperalimentation
0.893 0.107 0.000
H26 Other cataract
0.891 0.109 0.000
G40-G47 Episodic and paroxysmal disorders
0.890 0.110 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.888 0.112 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.887 0.113 0.000
O80.0 Spontaneous vertex delivery
0.887 0.113 0.000
E10.9 Without complications
0.886 0.114 0.000
I24 Other acute ischaemic heart diseases
0.885 0.115 0.000
Chapter V Mental and behavioural disorders
0.884 0.116 0.000
I47.2 Ventricular tachycardia
0.884 0.116 0.000
M45-M49 Spondylopathies
0.884 0.116 0.000
M47 Spondylosis
0.878 0.122 0.000
S40-S49 Injuries to the shoulder and upper arm
0.877 0.123 0.000
H26.9 Cataract, unspecified
0.874 0.126 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.873 0.127 0.000
I25 Chronic ischaemic heart disease
0.873 0.127 0.000
I72 Other aneurysm
0.871 0.129 0.000
H55-H59 Other disorders of eye and adnexa
0.868 0.132 0.000
S60-S69 Injuries to the wrist and hand
0.866 0.134 0.000
H72 Perforation of tympanic membrane
0.862 0.138 0.000
I47.1 Supraventricular tachycardia
0.862 0.138 0.000
T81 Complications of procedures, not elsewhere classified
0.862 0.138 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.861 0.139 0.000
Y83.6 Removal of other organ (partial) (total)
0.858 0.142 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.858 0.142 0.000
O20 Haemorrhage in early pregnancy
0.855 0.145 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.855 0.145 0.000
I05-I09 Chronic rheumatic heart diseases
0.855 0.145 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.852 0.148 0.000
I44.1 Atrioventricular block, second degree
0.851 0.149 0.000
H65 Nonsuppurative otitis media
0.846 0.154 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.840 0.160 0.000
M47.8 Other spondylosis
0.839 0.161 0.000
X50-X57 Overexertion, travel and privation
0.839 0.161 0.000
S20-S29 Injuries to the thorax
0.835 0.165 0.000
O21 Excessive vomiting in pregnancy
0.832 0.168 0.000
H30-H36 Disorders of choroid and retina
0.831 0.169 0.000
E66 Obesity
0.830 0.170 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.825 0.175 0.000
I77 Other disorders of arteries and arterioles
0.823 0.177 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.821 0.179 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.820 0.180 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.819 0.181 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.819 0.181 0.000
M47.82 Other spondylosis (Cervical region)
0.817 0.183 0.000
H43 Disorders of vitreous body
0.811 0.189 0.000
I73 Other peripheral vascular diseases
0.810 0.190 0.000
I35 Nonrheumatic aortic valve disorders
0.807 0.193 0.000
M48 Other spondylopathies
0.806 0.194 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.803 0.197 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.802 0.197 0.000
I38 Endocarditis, valve unspecified
0.802 0.198 0.000
G90-G99 Other disorders of the nervous system
0.802 0.198 0.000
E10.3 With ophthalmic complications
0.801 0.199 0.000
B15-B19 Viral hepatitis
0.798 0.202 0.000
I45.6 Preexcitation syndrome
0.797 0.203 0.000
I70 Atherosclerosis
0.796 0.204 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.795 0.205 0.000
W50-W64 Exposure to animate mechanical forces
0.795 0.205 0.000
S32 Fracture of lumbar spine and pelvis
0.793 0.207 0.000
I72.4 Aneurysm of artery of lower extremity
0.791 0.209 0.000
M47.9 Spondylosis, unspecified
0.790 0.210 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.789 0.211 0.000
Y00-Y09 Assault
0.784 0.216 0.000
S90-S99 Injuries to the ankle and foot
0.783 0.217 0.000
H60-H62 Diseases of external ear
0.781 0.219 0.000
E20-E35 Disorders of other endocrine glands
0.781 0.219 0.000
E66.8 Other obesity
0.780 0.220 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.778 0.222 0.000
F40 Phobic anxiety disorders
0.777 0.223 0.000
V10-V19 Pedal cyclist injured in transport accident
0.776 0.224 0.000
I24.8 Other forms of acute ischaemic heart disease
0.773 0.227 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.773 0.227 0.000
O80.9 Single spontaneous delivery, unspecified
0.772 0.228 0.000
I50.9 Heart failure, unspecified
0.771 0.229 0.000
H40.0 Glaucoma suspect
0.771 0.229 0.000
I42.9 Cardiomyopathy, unspecified
0.770 0.230 0.000
I25.5 Ischaemic cardiomyopathy
0.765 0.235 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.764 0.236 0.000
Y52 Agents primarily affecting the cardiovascular system
0.762 0.238 0.000
X20-X29 Contact with venomous animals and plants
0.761 0.239 0.000
I44.3 Other and unspecified atrioventricular block
0.761 0.239 0.000
I36 Nonrheumatic tricuspid valve disorders
0.761 0.239 0.000
I42.6 Alcoholic cardiomyopathy
0.761 0.239 0.000
O21.0 Mild hyperemesis gravidarum
0.760 0.240 0.000
B95-B98 Bacterial, viral and other infectious agents
0.758 0.242 0.000
T91 Sequelae of injuries of neck and trunk
0.756 0.244 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.756 0.244 0.000
X60-X84 Intentional self-harm
0.756 0.244 0.000
H10-H13 Disorders of conjunctiva
0.756 0.244 0.000
H40.2 Primary angle-closure glaucoma
0.755 0.245 0.000
I50.0 Congestive heart failure
0.753 0.247 0.000
M47.2 Other spondylosis with radiculopathy
0.752 0.248 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.752 0.248 0.000
G45.3 Amaurosis fugax
0.751 0.248 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.751 0.249 0.000
S40 Superficial injury of shoulder and upper arm
0.748 0.252 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.747 0.253 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.746 0.254 0.000
F40.2 Specific (isolated) phobias
0.746 0.254 0.000
H73 Other disorders of tympanic membrane
0.744 0.256 0.000
S10-S19 Injuries to the neck
0.744 0.256 0.000
Chapter XXII Codes for special purposes
0.743 0.257 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.743 0.257 0.000
H57 Other disorders of eye and adnexa
0.742 0.258 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.742 0.258 0.000
H35 Other retinal disorders
0.740 0.260 0.000
B07 Viral warts
0.739 0.261 0.000
H66 Suppurative and unspecified otitis media
0.739 0.261 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.738 0.261 0.000
M48.0 Spinal stenosis
0.738 0.262 0.000
B35-B49 Mycoses
0.737 0.263 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.736 0.263 0.000
I44.2 Atrioventricular block, complete
0.736 0.264 0.000
H80-H83 Diseases of inner ear
0.736 0.264 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.735 0.265 0.000
M40-M43 Deforming dorsopathies
0.734 0.266 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.734 0.266 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.734 0.266 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.731 0.269 0.000
T92 Sequelae of injuries of upper limb
0.731 0.269 0.000
I45.9 Conduction disorder, unspecified
0.730 0.270 0.000
H44 Disorders of globe
0.730 0.270 0.000
S50-S59 Injuries to the elbow and forearm
0.728 0.272 0.000
O85-O92 Complications predominantly related to the puerperium
0.728 0.272 0.000
B99-B99 Other infectious diseases
0.726 0.274 0.000
M80-M85 Disorders of bone density and structure
0.726 0.274 0.000
I74 Arterial embolism and thrombosis
0.726 0.274 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.725 0.275 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.724 0.275 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.724 0.276 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.721 0.278 0.000
Y44 Agents primarily affecting blood constituents
0.721 0.279 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.720 0.280 0.000
I42.8 Other cardiomyopathies
0.718 0.282 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.716 0.284 0.000
W20-W49 Exposure to inanimate mechanical forces
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
H65.4 Other chronic nonsuppurative otitis media
0.715 0.285 0.000
I45.8 Other specified conduction disorders
0.713 0.287 0.000
I45.4 Nonspecific intraventricular block
0.713 0.287 0.000
I45.3 Trifascicular block
0.713 0.287 0.000
I45.2 Bifascicular block
0.713 0.287 0.000
I45.0 Right fascicular block
0.713 0.287 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.713 0.287 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.712 0.288 0.000
I07 Rheumatic tricuspid valve diseases
0.712 0.288 0.000
G90 Disorders of autonomic nervous system
0.712 0.288 0.000
T66-T78 Other and unspecified effects of external causes
0.710 0.290 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.710 0.290 0.000
I44.5 Left posterior fascicular block
0.709 0.291 0.000
I44.4 Left anterior fascicular block
0.709 0.291 0.000
E10.4 With neurological complications
0.709 0.291 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.708 0.292 0.000
S61 Open wound of wrist and hand
0.708 0.292 0.000
T87 Complications peculiar to reattachment and amputation
0.707 0.293 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.707 0.293 0.000
Q80-Q89 Other congenital malformations
0.706 0.294 0.000
W00-W19 Falls
0.706 0.294 0.000
H35.0 Background retinopathy and retinal vascular changes
0.705 0.295 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.705 0.295 0.000
S64 Injury of nerves at wrist and hand level
0.704 0.296 0.000
Y83.9 Surgical procedure, unspecified
0.704 0.296 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.704 0.296 0.000
H18 Other disorders of cornea
0.703 0.297 0.000
I23 Certain current complications following acute myocardial infarction
0.702 0.298 0.000
Y48 Anaesthetics and therapeutic gases
0.701 0.299 0.000
I44.6 Other and unspecified fascicular block
0.701 0.299 0.000
X51 Travel and motion
0.700 0.300 0.000
H42 Glaucoma in diseases classified elsewhere
0.699 0.301 0.000
H55 Nystagmus and other irregular eye movements
0.697 0.303 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.696 0.304 0.000
H72.0 Central perforation of tympanic membrane
0.695 0.305 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.695 0.305 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.694 0.306 0.000
I73.9 Peripheral vascular disease, unspecified
0.694 0.306 0.000
I44.0 Atrioventricular block, first degree
0.694 0.306 0.000
I20.1 Angina pectoris with documented spasm
0.693 0.307 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.693 0.307 0.000
A80-A89 Viral infections of the central nervous system
0.693 0.307 0.000
T79-T79 Certain early complications of trauma
0.693 0.307 0.000
I47.0 Reentry ventricular arrhythmia
0.693 0.307 0.000
V80-V89 Other land transport accidents
0.692 0.308 0.000
G40 Epilepsy
0.691 0.309 0.000
E14 Unspecified diabetes mellitus
0.690 0.310 0.000
H40.1 Primary open-angle glaucoma
0.689 0.310 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.689 0.311 0.000
Y86 Sequelae of other accidents
0.689 0.311 0.000
M47.1 Other spondylosis with myelopathy
0.689 0.311 0.000
E10.5 With peripheral circulatory complications
0.689 0.311 0.000
I71 Aortic aneurysm and dissection
0.689 0.311 0.000
G20-G26 Extrapyramidal and movement disorders
0.688 0.312 0.000
H40.8 Other glaucoma
0.686 0.314 0.000
H40.6 Glaucoma secondary to drugs
0.686 0.314 0.000
H40.4 Glaucoma secondary to eye inflammation
0.686 0.314 0.000
H40.3 Glaucoma secondary to eye trauma
0.686 0.314 0.000
E13 Other specified diabetes mellitus
0.685 0.314 0.000
H16 Keratitis
0.685 0.315 0.000
T90 Sequelae of injuries of head
0.685 0.315 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.684 0.316 0.000
I42.5 Other restrictive cardiomyopathy
0.684 0.316 0.000
I42.4 Endocardial fibroelastosis
0.684 0.316 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.684 0.316 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.684 0.316 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.684 0.316 0.000
H74 Other disorders of middle ear and mastoid
0.683 0.317 0.000
H43.8 Other disorders of vitreous body
0.682 0.318 0.000
Y84.2 Radiological procedure and radiotherapy
0.682 0.318 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.681 0.319 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.681 0.319 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.680 0.320 0.000
B65-B83 Helminthiases
0.680 0.320 0.000
B50-B64 Protozoal diseases
0.680 0.320 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.680 0.320 0.000
A75-A79 Rickettsioses
0.680 0.320 0.000
A70-A74 Other diseases caused by chlamydiae
0.680 0.320 0.000
A65-A69 Other spirochaetal diseases
0.680 0.320 0.000
A20-A28 Certain zoonotic bacterial diseases
0.680 0.320 0.000
A15-A19 Tuberculosis
0.680 0.320 0.000
H53-H54 Visual disturbances and blindness
0.680 0.320 0.000
A30-A49 Other bacterial diseases
0.680 0.320 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.679 0.321 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.679 0.321 0.000
H70 Mastoiditis and related conditions
0.679 0.321 0.000
H68 Eustachian salpingitis and obstruction
0.679 0.321 0.000
H67 Otitis media in diseases classified elsewhere
0.679 0.321 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.678 0.322 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.677 0.323 0.000
H69 Other disorders of Eustachian tube
0.677 0.323 0.000
I31 Other diseases of pericardium
0.677 0.323 0.000
E65 Localised adiposity
0.677 0.323 0.000
O84 Multiple delivery
0.675 0.325 0.000
O83 Other assisted single delivery
0.675 0.325 0.000
O81 Single delivery by forceps and vacuum extractor
0.675 0.325 0.000
Y84.1 Kidney dialysis
0.675 0.325 0.000
S80-S89 Injuries to the knee and lower leg
0.675 0.325 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.674 0.325 0.000
Q00-Q07 Congenital malformations of the nervous system
0.674 0.326 0.000
Y83.3 Surgical operation with formation of external stoma
0.672 0.327 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.672 0.328 0.000
E12 Malnutrition-related diabetes mellitus
0.670 0.330 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.670 0.330 0.000
D80-D89 Certain disorders involving the immune mechanism
0.669 0.331 0.000
O29 Complications of anaesthesia during pregnancy
0.669 0.331 0.000
O28 Abnormal findings on antenatal screening of mother
0.669 0.331 0.000
O22 Venous complications in pregnancy
0.669 0.331 0.000
O25 Malnutrition in pregnancy
0.669 0.331 0.000
B15 Acute hepatitis A
0.669 0.331 0.000
Y83.5 Amputation of limb(s)
0.668 0.332 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.666 0.334 0.000
V20-V29 Motorcycle rider injured in transport accident
0.666 0.334 0.000
H71 Cholesteatoma of middle ear
0.666 0.334 0.000
S32.0 Fracture of lumbar vertebra
0.666 0.334 0.000
F45 Somatoform disorders
0.666 0.334 0.000
H43.1 Vitreous haemorrhage
0.664 0.336 0.000
F48 Other neurotic disorders
0.663 0.337 0.000
G41 Status epilepticus
0.663 0.337 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.662 0.338 0.000
H33 Retinal detachments and breaks
0.662 0.338 0.000
I77.6 Arteritis, unspecified
0.661 0.339 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.661 0.339 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.661 0.339 0.000
I78 Diseases of capillaries
0.661 0.339 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.660 0.340 0.000
O07 Failed attempted abortion
0.660 0.340 0.000
O06 Unspecified abortion
0.660 0.340 0.000
O05 Other abortion
0.660 0.340 0.000
O01 Hydatidiform mole
0.660 0.340 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.660 0.340 0.000
E10.8 With unspecified complications
0.659 0.341 0.000
E10.7 With multiple complications
0.659 0.341 0.000
E10.6 With other specified complications
0.659 0.341 0.000
E10.2 With renal complications
0.659 0.341 0.000
E10.0 With coma
0.659 0.341 0.000
Y59 Other and unspecified vaccines and biological substances
0.659 0.341 0.000
Y58 Bacterial vaccines
0.659 0.341 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.659 0.341 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.659 0.341 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.659 0.341 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.659 0.341 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.659 0.341 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.659 0.341 0.000
I05 Rheumatic mitral valve diseases
0.659 0.341 0.000
Y42.5 Other oestrogens and progestogens
0.659 0.341 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.659 0.341 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.658 0.342 0.000
O80.8 Other single spontaneous delivery
0.658 0.342 0.000
O80.1 Spontaneous breech delivery
0.658 0.342 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.658 0.342 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.657 0.343 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.657 0.343 0.000
H27 Other disorders of lens
0.657 0.343 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.657 0.343 0.000
I72.3 Aneurysm of iliac artery
0.657 0.343 0.000
B91 Sequelae of poliomyelitis
0.656 0.344 0.000
O82 Single delivery by Caesarean section
0.656 0.344 0.000
B25-B34 Other viral diseases
0.655 0.345 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.654 0.345 0.000
E10.1 With ketoacidosis
0.654 0.346 0.000
H20 Iridocyclitis
0.653 0.347 0.000
H90-H95 Other disorders of ear
0.653 0.347 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.653 0.347 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.653 0.347 0.000
G82 Paraplegia and tetraplegia
0.652 0.348 0.000
I49 Other cardiac arrhythmias
0.652 0.348 0.000
H26.4 After-cataract
0.652 0.348 0.000
T86 Failure and rejection of transplanted organs and tissues
0.651 0.348 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.651 0.349 0.000
I30 Acute pericarditis
0.650 0.349 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.650 0.350 0.000
W55 Bitten or struck by other mammals
0.650 0.350 0.000
Q50-Q56 Congenital malformations of genital organs
0.649 0.351 0.000
O04.8 Complete or unspecified, with other and unspecified complications
0.649 0.351 0.000
O04.7 Complete or unspecified, complicated by embolism
0.649 0.351 0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.649 0.351 0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.649 0.351 0.000
O04.4 Incomplete, without complication
0.649 0.351 0.000
O04.3 Incomplete, with other and unspecified complications
0.649 0.351 0.000
O04.2 Incomplete, complicated by embolism
0.649 0.351 0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage
0.649 0.351 0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection
0.649 0.351 0.000
S32.4 Fracture of acetabulum
0.649 0.351 0.000
S29 Other and unspecified injuries of thorax
0.648 0.352 0.000
H65.2 Chronic serous otitis media
0.647 0.353 0.000
X50 Overexertion and strenuous or repetitive movements
0.646 0.354 0.000
M91-M94 Chondropathies
0.645 0.355 0.000
I73.8 Other specified peripheral vascular diseases
0.645 0.355 0.000
H72.8 Other perforations of tympanic membrane
0.645 0.355 0.000
Q60-Q64 Congenital malformations of the urinary system
0.644 0.356 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.644 0.356 0.000
M60-M63 Disorders of muscles
0.644 0.356 0.000
E50-E64 Other nutritional deficiencies
0.643 0.357 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.642 0.357 0.000
S37 Injury of urinary and pelvic organs
0.642 0.357 0.000
S36 Injury of intra-abdominal organs
0.642 0.357 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.642 0.357 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.642 0.357 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.642 0.357 0.000
S31 Open wound of abdomen, lower back and pelvis
0.642 0.357 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.642 0.358 0.000
M48.06 Spinal stenosis (Lumbar region)
0.641 0.359 0.000
T98 Sequelae of other and unspecified effects of external causes
0.641 0.359 0.000
T95 Sequelae of burns, corrosions and frostbite
0.641 0.359 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.641 0.359 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.641 0.359 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.641 0.359 0.000
G81 Hemiplegia
0.641 0.359 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.641 0.359 0.000
E67 Other hyperalimentation
0.640 0.359 0.000
E68 Sequelae of hyperalimentation
0.640 0.359 0.000
G80 Infantile cerebral palsy
0.640 0.360 0.000
I20.8 Other forms of angina pectoris
0.639 0.360 0.000
H26.3 Drug-induced cataract
0.639 0.361 0.000
H26.2 Complicated cataract
0.639 0.361 0.000
H26.0 Infantile, juvenile and presenile cataract
0.639 0.361 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.638 0.362 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.638 0.362 0.000
T93 Sequelae of injuries of lower limb
0.638 0.362 0.000
O24 Diabetes mellitus in pregnancy
0.638 0.362 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.638 0.362 0.000
I08 Multiple valve diseases
0.637 0.363 0.000
M00-M03 Infectious arthropathies
0.636 0.363 0.000
H40.5 Glaucoma secondary to other eye disorders
0.636 0.364 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.636 0.364 0.000
I77.1 Stricture of artery
0.635 0.364 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.635 0.365 0.000
Y40 Systemic antibiotics
0.635 0.365 0.000
O23 Infections of genito-urinary tract in pregnancy
0.634 0.365 0.000
Y83.8 Other surgical procedures
0.634 0.366 0.000
I24.1 Dressler's syndrome
0.634 0.366 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.634 0.366 0.000
F70-F79 Mental retardation
0.634 0.366 0.000
F60-F69 Disorders of adult personality and behaviour
0.634 0.366 0.000
M49 Spondylopathies in diseases classified elsewhere
0.634 0.366 0.000
S60 Superficial injury of wrist and hand
0.633 0.367 0.000
I22 Subsequent myocardial infarction
0.633 0.367 0.000
S70-S79 Injuries to the hip and thigh
0.633 0.367 0.000
F42 Obsessive-compulsive disorder
0.632 0.367 0.000
O20.0 Threatened abortion
0.632 0.368 0.000
Y00 Assault by blunt object
0.632 0.368 0.000
Y84.8 Other medical procedures
0.631 0.369 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.631 0.369 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.630 0.370 0.000
O00 Ectopic pregnancy
0.630 0.370 0.000
H26.8 Other specified cataract
0.630 0.370 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.629 0.371 0.000
S48 Traumatic amputation of shoulder and upper arm
0.629 0.371 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.629 0.371 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.629 0.371 0.000
S44 Injury of nerves at shoulder and upper arm level
0.629 0.371 0.000
S41 Open wound of shoulder and upper arm
0.629 0.371 0.000
S47 Crushing injury of shoulder and upper arm
0.629 0.371 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.628 0.372 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.628 0.372 0.000
M45 Ankylosing spondylitis
0.627 0.373 0.000
S62 Fracture at wrist and hand level
0.626 0.373 0.000
T92.1 Sequelae of fracture of arm
0.626 0.374 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.626 0.374 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.626 0.374 0.000
G45.0 Vertebro-basilar artery syndrome
0.626 0.374 0.000
I45.5 Other specified heart block
0.626 0.374 0.000
I25.6 Silent myocardial ischaemia
0.626 0.374 0.000
I25.4 Coronary artery aneurysm
0.626 0.374 0.000
I25.3 Aneurysm of heart
0.626 0.374 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.626 0.374 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.625 0.375 0.000
Y57 Other and unspecified drugs and medicaments
0.624 0.376 0.000
I72.9 Aneurysm of unspecified site
0.624 0.376 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.624 0.376 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.624 0.376 0.000
I72.2 Aneurysm of renal artery
0.624 0.376 0.000
I72.1 Aneurysm of artery of upper extremity
0.624 0.376 0.000
I72.0 Aneurysm of carotid artery
0.624 0.376 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.624 0.376 0.000
S27 Injury of other and unspecified intrathoracic organs
0.624 0.376 0.000
F80-F89 Disorders of psychological development
0.624 0.376 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.623 0.377 0.000
M48.02 Spinal stenosis (Cervical region)
0.623 0.377 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.623 0.377 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.622 0.378 0.000
S65 Injury of blood vessels at wrist and hand level
0.621 0.379 0.000
G30-G32 Other degenerative diseases of the nervous system
0.621 0.379 0.000
M70-M79 Other soft tissue disorders
0.620 0.380 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.620 0.380 0.000
H43.3 Other vitreous opacities
0.620 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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