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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12754465
log Bayes Factor = 13.0653
Chromosome 1   position 74,675,210  (GRCh37) Explore rs12754465 on Ensembl!
Variant rs12754465 is part of Cluster X0072

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
J09-J18 Influenza and pneumonia
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.996 0.004 0.000
E70-E90 Metabolic disorders
0.995 0.005 0.000
D10-D36 Benign neoplasms
0.995 0.005 0.000
J18 Pneumonia, organism unspecified
0.994 0.006 0.000
J18.9 Pneumonia, unspecified
0.994 0.006 0.000
C34 Malignant neoplasm of bronchus and lung
0.994 0.006 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.993 0.007 0.000
I95 Hypotension
0.989 0.011 0.000
C34.1 Upper lobe, bronchus or lung
0.987 0.013 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.983 0.017 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.982 0.018 0.000
D24 Benign neoplasm of breast
0.979 0.021 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.970 0.030 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.969 0.031 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.965 0.035 0.000
S80-S89 Injuries to the knee and lower leg
0.965 0.035 0.000
I73 Other peripheral vascular diseases
0.964 0.036 0.000
Chapter XX External causes of morbidity and mortality
0.961 0.039 0.000
I95.1 Orthostatic hypotension
0.956 0.044 0.000
I73.9 Peripheral vascular disease, unspecified
0.950 0.050 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.948 0.052 0.000
E65-E68 Obesity and other hyperalimentation
0.948 0.052 0.000
D25 Leiomyoma of uterus
0.945 0.055 0.000
I30-I52 Other forms of heart disease
0.944 0.056 0.000
F30-F39 Mood [affective] disorders
0.941 0.059 0.000
Chapter I Certain infectious and parasitic diseases
0.937 0.063 0.000
I95.9 Hypotension, unspecified
0.932 0.068 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.932 0.068 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.925 0.075 0.000
E83 Disorders of mineral metabolism
0.925 0.075 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.923 0.077 0.000
D17 Benign lipomatous neoplasm
0.922 0.078 0.000
J95-J99 Other diseases of the respiratory system
0.919 0.081 0.000
I51 Complications and ill-defined descriptions of heart disease
0.917 0.083 0.000
C34.9 Bronchus or lung, unspecified
0.916 0.084 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.914 0.086 0.000
E66 Obesity
0.911 0.089 0.000
C83.3 Large cell (diffuse)
0.905 0.095 0.000
F10.2 Dependence syndrome
0.894 0.106 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.891 0.109 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.888 0.112 0.000
I51.7 Cardiomegaly
0.886 0.114 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.885 0.115 0.000
E66.9 Obesity, unspecified
0.884 0.116 0.000
A30-A49 Other bacterial diseases
0.884 0.116 0.000
E87.2 Acidosis
0.880 0.120 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.874 0.126 0.000
D27 Benign neoplasm of ovary
0.872 0.128 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.872 0.128 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.871 0.129 0.000
I72 Other aneurysm
0.871 0.129 0.000
D25.1 Intramural leiomyoma of uterus
0.864 0.136 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.861 0.139 0.000
I47 Paroxysmal tachycardia
0.861 0.139 0.000
J98 Other respiratory disorders
0.858 0.142 0.000
E20-E35 Disorders of other endocrine glands
0.856 0.144 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.854 0.146 0.000
E89.0 Postprocedural hypothyroidism
0.853 0.147 0.000
S82 Fracture of lower leg, including ankle
0.851 0.149 0.000
I34 Nonrheumatic mitral valve disorders
0.850 0.150 0.000
E83.5 Disorders of calcium metabolism
0.845 0.155 0.000
F10.3 Withdrawal state
0.842 0.158 0.000
B35-B49 Mycoses
0.840 0.160 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.836 0.164 0.000
F31 Bipolar affective disorder
0.836 0.164 0.000
J14 Pneumonia due to Haemophilus influenzae
0.835 0.164 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.833 0.167 0.000
S10-S19 Injuries to the neck
0.832 0.168 0.000
C79 Secondary malignant neoplasm of other sites
0.829 0.171 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.828 0.172 0.000
I95.8 Other hypotension
0.827 0.173 0.000
D36 Benign neoplasm of other and unspecified sites
0.823 0.177 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.822 0.178 0.000
I74 Arterial embolism and thrombosis
0.821 0.178 0.000
J81 Pulmonary oedema
0.821 0.179 0.000
V40-V49 Car occupant injured in transport accident
0.821 0.179 0.000
I10-I15 Hypertensive diseases
0.819 0.181 0.000
S60-S69 Injuries to the wrist and hand
0.818 0.182 0.000
D25.0 Submucous leiomyoma of uterus
0.817 0.183 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.816 0.184 0.000
F32 Depressive episode
0.815 0.185 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.814 0.185 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.812 0.188 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.812 0.188 0.000
I42 Cardiomyopathy
0.811 0.189 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.809 0.191 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.808 0.192 0.000
T66-T78 Other and unspecified effects of external causes
0.807 0.193 0.000
F10.0 Acute intoxication
0.807 0.193 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.806 0.194 0.000
R42 Dizziness and giddiness
0.806 0.194 0.000
S82.8 Fractures of other parts of lower leg
0.803 0.197 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.803 0.197 0.000
C51-C58 Malignant neoplasms of female genital organs
0.802 0.198 0.000
S80 Superficial injury of lower leg
0.801 0.199 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.800 0.200 0.000
I95.2 Hypotension due to drugs
0.800 0.200 0.000
E50-E64 Other nutritional deficiencies
0.798 0.202 0.000
E87.7 Fluid overload
0.796 0.204 0.000
F80-F89 Disorders of psychological development
0.796 0.204 0.000
Chapter VI Diseases of the nervous system
0.795 0.205 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.795 0.205 0.000
E87.5 Hyperkalaemia
0.794 0.206 0.000
C50-C50 Malignant neoplasm of breast
0.794 0.206 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.789 0.211 0.000
Chapter XXII Codes for special purposes
0.789 0.211 0.000
D47.2 Monoclonal gammopathy
0.788 0.212 0.000
T79-T79 Certain early complications of trauma
0.787 0.213 0.000
J98.4 Other disorders of lung
0.787 0.213 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.786 0.214 0.000
D37.4 Colon
0.785 0.215 0.000
S81 Open wound of lower leg
0.783 0.217 0.000
D34 Benign neoplasm of thyroid gland
0.783 0.217 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.781 0.219 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.781 0.219 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.781 0.219 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.780 0.220 0.000
X20-X29 Contact with venomous animals and plants
0.778 0.222 0.000
E73 Lactose intolerance
0.778 0.222 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.778 0.222 0.000
A00-A09 Intestinal infectious diseases
0.778 0.222 0.000
F10.4 Withdrawal state with delirium
0.776 0.224 0.000
D25.9 Leiomyoma of uterus, unspecified
0.775 0.225 0.000
I72.8 Aneurysm of other specified arteries
0.774 0.226 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.774 0.226 0.000
R40 Somnolence, stupor and coma
0.774 0.226 0.000
E87.3 Alkalosis
0.773 0.227 0.000
D47.1 Chronic myeloproliferative disease
0.772 0.228 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.769 0.231 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.769 0.231 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.769 0.231 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.765 0.235 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.765 0.235 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.763 0.237 0.000
I47.2 Ventricular tachycardia
0.762 0.238 0.000
R45 Symptoms and signs involving emotional state
0.762 0.238 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.761 0.238 0.000
A49 Bacterial infection of unspecified site
0.760 0.240 0.000
W00-W19 Falls
0.759 0.241 0.000
C32 Malignant neoplasm of larynx
0.758 0.242 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.758 0.242 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.757 0.243 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.756 0.244 0.000
B37 Candidiasis
0.754 0.246 0.000
J00-J06 Acute upper respiratory infections
0.753 0.246 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.752 0.248 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.747 0.253 0.000
E83.3 Disorders of phosphorus metabolism
0.743 0.257 0.000
Y00-Y09 Assault
0.743 0.257 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.742 0.258 0.000
C15-C26 Malignant neoplasms of digestive organs
0.741 0.259 0.000
I83 Varicose veins of lower extremities
0.740 0.260 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.740 0.260 0.000
J11 Influenza, virus not identified
0.739 0.261 0.000
R27 Other lack of coordination
0.739 0.261 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.739 0.261 0.000
A48 Other bacterial diseases, not elsewhere classified
0.738 0.262 0.000
I12 Hypertensive renal disease
0.738 0.262 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.738 0.262 0.000
F11 Mental and behavioural disorders due to use of opioids
0.736 0.264 0.000
C81 Hodgkin's disease
0.736 0.264 0.000
D30 Benign neoplasm of urinary organs
0.736 0.264 0.000
I49 Other cardiac arrhythmias
0.734 0.266 0.000
D47.4 Osteomyelofibrosis
0.734 0.266 0.000
I34.1 Mitral (valve) prolapse
0.733 0.267 0.000
J10 Influenza due to identified influenza virus
0.733 0.267 0.000
E86 Volume depletion
0.732 0.268 0.000
D48.1 Connective and other soft tissue
0.732 0.268 0.000
D00-D09 In situ neoplasms
0.731 0.269 0.000
D46 Myelodysplastic syndromes
0.730 0.270 0.000
S90-S99 Injuries to the ankle and foot
0.728 0.272 0.000
E27 Other disorders of adrenal gland
0.728 0.272 0.000
F33 Recurrent depressive disorder
0.728 0.272 0.000
E83.4 Disorders of magnesium metabolism
0.728 0.272 0.000
G40-G47 Episodic and paroxysmal disorders
0.727 0.273 0.000
E89.2 Postprocedural hypoparathyroidism
0.726 0.274 0.000
A41 Other septicaemia
0.725 0.275 0.000
I44 Atrioventricular and left bundle-branch block
0.724 0.275 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.723 0.277 0.000
Chapter VIII Diseases of the ear and mastoid process
0.723 0.277 0.000
S89 Other and unspecified injuries of lower leg
0.721 0.279 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.720 0.280 0.000
D48.6 Breast
0.720 0.280 0.000
G43 Migraine
0.720 0.280 0.000
C34.3 Lower lobe, bronchus or lung
0.720 0.280 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.719 0.281 0.000
I51.9 Heart disease, unspecified
0.719 0.281 0.000
E87.6 Hypokalaemia
0.718 0.282 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.718 0.282 0.000
I72.3 Aneurysm of iliac artery
0.718 0.282 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
J17 Pneumonia in diseases classified elsewhere
0.715 0.285 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.715 0.285 0.000
J12 Viral pneumonia, not elsewhere classified
0.715 0.285 0.000
J09 Influenza due to certain identified influenza virus
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.714 0.285 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.714 0.285 0.000
C31 Malignant neoplasm of accessory sinuses
0.714 0.285 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.714 0.285 0.000
C37 Malignant neoplasm of thymus
0.714 0.285 0.000
C33 Malignant neoplasm of trachea
0.714 0.285 0.000
I47.1 Supraventricular tachycardia
0.714 0.286 0.000
G43.9 Migraine, unspecified
0.714 0.286 0.000
E85 Amyloidosis
0.714 0.286 0.000
E84 Cystic fibrosis
0.714 0.286 0.000
E79 Disorders of purine and pyrimidine metabolism
0.714 0.286 0.000
E77 Disorders of glycoprotein metabolism
0.714 0.286 0.000
E76 Disorders of glycosaminoglycan metabolism
0.714 0.286 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.714 0.286 0.000
E74 Other disorders of carbohydrate metabolism
0.714 0.286 0.000
E72 Other disorders of amino-acid metabolism
0.714 0.286 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.714 0.286 0.000
E70 Disorders of aromatic amino-acid metabolism
0.714 0.286 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.714 0.286 0.000
D31 Benign neoplasm of eye and adnexa
0.713 0.286 0.000
D29 Benign neoplasm of male genital organs
0.713 0.286 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.713 0.286 0.000
D19 Benign neoplasm of mesothelial tissue
0.713 0.286 0.000
D16 Benign neoplasm of bone and articular cartilage
0.713 0.286 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.713 0.286 0.000
R40.0 Somnolence
0.713 0.287 0.000
I34.0 Mitral (valve) insufficiency
0.713 0.287 0.000
J18.8 Other pneumonia, organism unspecified
0.713 0.287 0.000
J18.2 Hypostatic pneumonia, unspecified
0.713 0.287 0.000
C34.8 Overlapping lesion of bronchus and lung
0.712 0.288 0.000
C34.2 Middle lobe, bronchus or lung
0.712 0.288 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.712 0.288 0.000
I73.0 Raynaud's syndrome
0.712 0.288 0.000
I99 Other and unspecified disorders of circulatory system
0.711 0.289 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.710 0.290 0.000
I95.0 Idiopathic hypotension
0.709 0.291 0.000
I30 Acute pericarditis
0.709 0.291 0.000
E40-E46 Malnutrition
0.708 0.292 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.707 0.292 0.000
X50-X57 Overexertion, travel and privation
0.707 0.293 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.707 0.293 0.000
F32.9 Depressive episode, unspecified
0.707 0.293 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.706 0.294 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.705 0.295 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.705 0.295 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.705 0.295 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.705 0.295 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.705 0.295 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.704 0.295 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.704 0.296 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.701 0.299 0.000
I70 Atherosclerosis
0.700 0.299 0.000
I51.8 Other ill-defined heart diseases
0.700 0.300 0.000
V20-V29 Motorcycle rider injured in transport accident
0.700 0.300 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.699 0.301 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.697 0.303 0.000
I42.0 Dilated cardiomyopathy
0.697 0.303 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.695 0.304 0.000
C95 Leukaemia of unspecified cell type
0.695 0.304 0.000
C94 Other leukaemias of specified cell type
0.695 0.304 0.000
C93 Monocytic leukaemia
0.695 0.304 0.000
C88 Malignant immunoproliferative diseases
0.695 0.304 0.000
C86 Other specified types of T/NK-cell lymphoma
0.695 0.304 0.000
F31.7 Bipolar affective disorder, currently in remission
0.695 0.305 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.695 0.305 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.695 0.305 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.695 0.305 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.695 0.305 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.695 0.305 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.695 0.305 0.000
D26 Other benign neoplasms of uterus
0.694 0.306 0.000
E87.4 Mixed disorder of acid-base balance
0.692 0.308 0.000
S88 Traumatic amputation of lower leg
0.692 0.308 0.000
S87 Crushing injury of lower leg
0.692 0.308 0.000
S86 Injury of muscle and tendon at lower leg level
0.692 0.308 0.000
S85 Injury of blood vessels at lower leg level
0.692 0.308 0.000
S84 Injury of nerves at lower leg level
0.692 0.308 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.692 0.308 0.000
F32.1 Moderate depressive episode
0.692 0.308 0.000
I73.8 Other specified peripheral vascular diseases
0.691 0.309 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.691 0.309 0.000
S80.9 Superficial injury of lower leg, unspecified
0.691 0.309 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.690 0.309 0.000
Y35-Y36 Legal intervention and operations of war
0.689 0.311 0.000
Y10-Y34 Event of undetermined intent
0.689 0.311 0.000
X85-X99 Assault
0.689 0.311 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.689 0.311 0.000
X30-X39 Exposure to forces of nature
0.689 0.311 0.000
X10-X19 Contact with heat and hot substances
0.689 0.311 0.000
X00-X09 Exposure to smoke, fire and flames
0.689 0.311 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.689 0.311 0.000
W75-W84 Other accidental threats to breathing
0.689 0.311 0.000
W65-W74 Accidental drowning and submersion
0.689 0.311 0.000
W50-W64 Exposure to animate mechanical forces
0.689 0.311 0.000
V98-V99 Other and unspecified transport accidents
0.689 0.311 0.000
V95-V97 Air and space transport accidents
0.689 0.311 0.000
V90-V94 Water transport accidents
0.689 0.311 0.000
V80-V89 Other land transport accidents
0.689 0.311 0.000
V70-V79 Bus occupant injured in transport accident
0.689 0.311 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.689 0.311 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.689 0.311 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.689 0.311 0.000
V01-V09 Pedestrian injured in transport accident
0.689 0.311 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.688 0.312 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.688 0.312 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.686 0.314 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.684 0.316 0.000
J98.9 Respiratory disorder, unspecified
0.684 0.316 0.000
F60-F69 Disorders of adult personality and behaviour
0.683 0.317 0.000
I12.0 Hypertensive renal disease with renal failure
0.683 0.317 0.000
C45 Mesothelioma
0.680 0.320 0.000
F10.9 Unspecified mental and behavioural disorder
0.680 0.320 0.000
F10.8 Other mental and behavioural disorders
0.680 0.320 0.000
F10.7 Residual and late-onset psychotic disorder
0.680 0.320 0.000
F10.6 Amnesic syndrome
0.680 0.320 0.000
F10.5 Psychotic disorder
0.680 0.320 0.000
X60-X84 Intentional self-harm
0.680 0.320 0.000
E67 Other hyperalimentation
0.679 0.321 0.000
E68 Sequelae of hyperalimentation
0.679 0.321 0.000
E65 Localised adiposity
0.679 0.321 0.000
C56 Malignant neoplasm of ovary
0.678 0.322 0.000
J98.8 Other specified respiratory disorders
0.677 0.323 0.000
T92 Sequelae of injuries of upper limb
0.677 0.323 0.000
I52 Other heart disorders in diseases classified elsewhere
0.677 0.323 0.000
I48 Atrial fibrillation and flutter
0.677 0.323 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.677 0.323 0.000
I41 Myocarditis in diseases classified elsewhere
0.677 0.323 0.000
I40 Acute myocarditis
0.677 0.323 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.677 0.323 0.000
I37 Pulmonary valve disorders
0.677 0.323 0.000
I36 Nonrheumatic tricuspid valve disorders
0.677 0.323 0.000
I32 Pericarditis in diseases classified elsewhere
0.677 0.323 0.000
E87.0 Hyperosmolality and hypernatraemia
0.675 0.325 0.000
F38 Other mood [affective] disorders
0.675 0.325 0.000
F34 Persistent mood [affective] disorders
0.675 0.325 0.000
F30 Manic episode
0.675 0.325 0.000
F39 Unspecified mood [affective] disorder
0.675 0.325 0.000
A40 Streptococcal septicaemia
0.675 0.325 0.000
R46 Symptoms and signs involving appearance and behaviour
0.674 0.326 0.000
I05-I09 Chronic rheumatic heart diseases
0.673 0.326 0.000
F43 Reaction to severe stress, and adjustment disorders
0.673 0.326 0.000
B99-B99 Other infectious diseases
0.672 0.328 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.672 0.328 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.672 0.328 0.000
B65-B83 Helminthiases
0.672 0.328 0.000
B50-B64 Protozoal diseases
0.672 0.328 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.672 0.328 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.672 0.328 0.000
A80-A89 Viral infections of the central nervous system
0.672 0.328 0.000
A75-A79 Rickettsioses
0.672 0.328 0.000
A70-A74 Other diseases caused by chlamydiae
0.672 0.328 0.000
A65-A69 Other spirochaetal diseases
0.672 0.328 0.000
A20-A28 Certain zoonotic bacterial diseases
0.672 0.328 0.000
A15-A19 Tuberculosis
0.672 0.328 0.000
S10 Superficial injury of neck
0.671 0.329 0.000
E80.4 Gilbert's syndrome
0.670 0.330 0.000
J20-J22 Other acute lower respiratory infections
0.670 0.330 0.000
D10 Benign neoplasm of mouth and pharynx
0.670 0.330 0.000
B37.0 Candidal stomatitis
0.670 0.330 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.668 0.331 0.000
I11 Hypertensive heart disease
0.668 0.332 0.000
T78 Adverse effects, not elsewhere classified
0.668 0.332 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.668 0.332 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.668 0.332 0.000
C83.7 Burkitt's tumour
0.668 0.332 0.000
C83.6 Undifferentiated (diffuse)
0.668 0.332 0.000
C83.5 Lymphoblastic (diffuse)
0.668 0.332 0.000
C83.4 Immunoblastic (diffuse)
0.668 0.332 0.000
C83.2 Mixed small and large cell (diffuse)
0.668 0.332 0.000
C83.1 Small cleaved cell (diffuse)
0.668 0.332 0.000
E66.8 Other obesity
0.667 0.332 0.000
B25-B34 Other viral diseases
0.667 0.333 0.000
R41.2 Retrograde amnesia
0.666 0.334 0.000
A41.9 Septicaemia, unspecified
0.666 0.334 0.000
S12 Fracture of neck
0.666 0.334 0.000
I78 Diseases of capillaries
0.666 0.334 0.000
C83.0 Small cell (diffuse)
0.665 0.334 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.665 0.335 0.000
S82.3 Fracture of lower end of tibia
0.665 0.335 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.665 0.335 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.664 0.336 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.664 0.336 0.000
S82.1 Fracture of upper end of tibia
0.664 0.336 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.664 0.336 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.664 0.336 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.663 0.337 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.663 0.337 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.663 0.337 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.663 0.337 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.663 0.337 0.000
E83.8 Other disorders of mineral metabolism
0.663 0.337 0.000
E83.2 Disorders of zinc metabolism
0.663 0.337 0.000
E83.0 Disorders of copper metabolism
0.663 0.337 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.662 0.338 0.000
D48.0 Bone and articular cartilage
0.662 0.338 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.662 0.338 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.662 0.338 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.662 0.338 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.662 0.338 0.000
E89.5 Postprocedural testicular hypofunction
0.662 0.338 0.000
E89.4 Postprocedural ovarian failure
0.662 0.338 0.000
E89.3 Postprocedural hypopituitarism
0.662 0.338 0.000
E89.1 Postprocedural hypoinsulinaemia
0.662 0.338 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.662 0.338 0.000
Y40 Systemic antibiotics
0.661 0.339 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.661 0.339 0.000
J60-J70 Lung diseases due to external agents
0.661 0.339 0.000
E55 Vitamin D deficiency
0.661 0.339 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.661 0.339 0.000
T82.3 Mechanical complication of other vascular grafts
0.661 0.339 0.000
F40 Phobic anxiety disorders
0.660 0.340 0.000
Y95 Nosocomial condition
0.660 0.340 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.660 0.340 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.660 0.340 0.000
F23 Acute and transient psychotic disorders
0.659 0.341 0.000
J96 Respiratory failure, not elsewhere classified
0.659 0.341 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.659 0.341 0.000
C90.0 Multiple myeloma
0.659 0.341 0.000
S32 Fracture of lumbar spine and pelvis
0.659 0.341 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.658 0.342 0.000
F99-F99 Unspecified mental disorder
0.658 0.342 0.000
Y43 Primarily systemic agents
0.658 0.342 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.658 0.342 0.000
I51.6 Cardiovascular disease, unspecified
0.657 0.343 0.000
I51.5 Myocardial degeneration
0.657 0.343 0.000
I51.4 Myocarditis, unspecified
0.657 0.343 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.657 0.343 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.657 0.343 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.657 0.343 0.000
I51.0 Cardiac septal defect, acquired
0.657 0.343 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.657 0.343 0.000
E23 Hypofunction and other disorders of pituitary gland
0.657 0.343 0.000
S67 Crushing injury of wrist and hand
0.656 0.344 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.655 0.344 0.000
J84 Other interstitial pulmonary diseases
0.656 0.344 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.655 0.345 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.655 0.345 0.000
J18.0 Bronchopneumonia, unspecified
0.654 0.346 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.654 0.346 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.653 0.347 0.000
E66.1 Drug-induced obesity
0.653 0.347 0.000
E66.0 Obesity due to excess calories
0.653 0.347 0.000
S81.8 Open wound of other parts of lower leg
0.653 0.347 0.000
R45.8 Other symptoms and signs involving emotional state
0.653 0.347 0.000
E24 Cushing's syndrome
0.652 0.347 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.652 0.348 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.652 0.348 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.651 0.349 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.651 0.349 0.000
A49.8 Other bacterial infections of unspecified site
0.651 0.349 0.000
T85.2 Mechanical complication of intraocular lens
0.651 0.349 0.000
C85.1 B-cell lymphoma, unspecified
0.650 0.350 0.000
S40-S49 Injuries to the shoulder and upper arm
0.649 0.350 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.649 0.351 0.000
S83.2 Tear of meniscus, current
0.649 0.351 0.000
V10-V19 Pedal cyclist injured in transport accident
0.649 0.351 0.000
D32 Benign neoplasm of meninges
0.648 0.352 0.000
C79.2 Secondary malignant neoplasm of skin
0.648 0.352 0.000
S50-S59 Injuries to the elbow and forearm
0.648 0.352 0.000
J03 Acute tonsillitis
0.648 0.352 0.000
F29 Unspecified nonorganic psychosis
0.648 0.352 0.000
X23 Contact with hornets, wasps and bees
0.647 0.353 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.647 0.353 0.000
I87 Other disorders of veins
0.647 0.353 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.647 0.353 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.647 0.353 0.000
D45 Polycythaemia vera
0.646 0.354 0.000
R41.0 Disorientation, unspecified
0.646 0.354 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.646 0.354 0.000
C50 Malignant neoplasm of breast
0.646 0.354 0.000
C78.7 Secondary malignant neoplasm of liver
0.645 0.355 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.645 0.355 0.000
C78.0 Secondary malignant neoplasm of lung
0.645 0.355 0.000
S64 Injury of nerves at wrist and hand level
0.643 0.357 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.643 0.357 0.000
C34.0 Main bronchus
0.642 0.357 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.642 0.358 0.000
S20-S29 Injuries to the thorax
0.641 0.359 0.000
F81 Specific developmental disorders of scholastic skills
0.641 0.359 0.000
R27.8 Other and unspecified lack of coordination
0.640 0.360 0.000
E22 Hyperfunction of pituitary gland
0.640 0.360 0.000
B44 Aspergillosis
0.639 0.361 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.639 0.361 0.000
R06 Abnormalities of breathing
0.638 0.362 0.000
I42.9 Cardiomyopathy, unspecified
0.638 0.362 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.637 0.362 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.637 0.363 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.637 0.363 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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