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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12863935
log Bayes Factor = 20.8798
Chromosome 13   position 23,971,938  (GRCh37) Explore rs12863935 on Ensembl!
Variant rs12863935 is part of Cluster X0047

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Z51 Other medical care
0.998 0.002 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.995 0.005 0.000
M20-M25 Other joint disorders
0.994 0.006 0.000
Z51.0 Radiotherapy session
0.992 0.008 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.991 0.009 0.000
Z92 Personal history of medical treatment
0.990 0.010 0.000
R50-R69 General symptoms and signs
0.990 0.010 0.000
E70-E90 Metabolic disorders
0.986 0.014 0.000
R59 Enlarged lymph nodes
0.984 0.016 0.000
E65-E68 Obesity and other hyperalimentation
0.984 0.016 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.982 0.018 0.000
C78.7 Secondary malignant neoplasm of liver
0.980 0.020 0.000
C15-C26 Malignant neoplasms of digestive organs
0.977 0.023 0.000
E66 Obesity
0.974 0.026 0.000
S00-S09 Injuries to the head
0.974 0.026 0.000
R59.0 Localised enlarged lymph nodes
0.968 0.032 0.000
Chapter I Certain infectious and parasitic diseases
0.968 0.032 0.000
Chapter VI Diseases of the nervous system
0.968 0.032 0.000
M25 Other joint disorders, not elsewhere classified
0.967 0.033 0.000
E66.9 Obesity, unspecified
0.967 0.033 0.000
D00-D09 In situ neoplasms
0.959 0.041 0.000
E83 Disorders of mineral metabolism
0.945 0.055 0.000
M23 Internal derangement of knee
0.944 0.056 0.000
M25.5 Pain in joint
0.943 0.057 0.000
Chapter VIII Diseases of the ear and mastoid process
0.941 0.059 0.000
Z96 Presence of other functional implants
0.936 0.064 0.000
G40-G47 Episodic and paroxysmal disorders
0.934 0.066 0.000
Z93 Artificial opening status
0.934 0.066 0.000
Z85 Personal history of malignant neoplasm
0.932 0.068 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.931 0.069 0.000
Chapter V Mental and behavioural disorders
0.930 0.070 0.000
S80-S89 Injuries to the knee and lower leg
0.930 0.070 0.000
Chapter XIV Diseases of the genitourinary system
0.929 0.071 0.000
Z51.5 Palliative care
0.928 0.072 0.000
M15-M19 Arthrosis
0.925 0.075 0.000
B95-B98 Bacterial, viral and other infectious agents
0.925 0.075 0.000
R51 Headache
0.923 0.077 0.000
N30-N39 Other diseases of urinary system
0.920 0.080 0.000
G43 Migraine
0.917 0.083 0.000
Z89 Acquired absence of limb
0.917 0.083 0.000
N39 Other disorders of urinary system
0.916 0.084 0.000
R59.1 Generalised enlarged lymph nodes
0.916 0.084 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.916 0.084 0.000
S01 Open wound of head
0.913 0.087 0.000
N39.0 Urinary tract infection, site not specified
0.912 0.088 0.000
R56 Convulsions, not elsewhere classified
0.911 0.089 0.000
E10-E14 Diabetes mellitus
0.909 0.091 0.000
C78.2 Secondary malignant neoplasm of pleura
0.903 0.097 0.000
E83.5 Disorders of calcium metabolism
0.902 0.098 0.000
C79 Secondary malignant neoplasm of other sites
0.902 0.098 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.901 0.099 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.900 0.100 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.900 0.100 0.000
C80 Malignant neoplasm without specification of site
0.896 0.104 0.000
G43.9 Migraine, unspecified
0.895 0.105 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.893 0.107 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.893 0.107 0.000
D03 Melanoma in situ
0.892 0.108 0.000
M25.56 Pain in joint (Lower leg)
0.890 0.110 0.000
Z83 Family history of other specific disorders
0.888 0.112 0.000
M17 Gonarthrosis [arthrosis of knee]
0.886 0.114 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.885 0.115 0.000
N39.8 Other specified disorders of urinary system
0.885 0.115 0.000
H65-H75 Diseases of middle ear and mastoid
0.882 0.118 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.880 0.120 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.879 0.121 0.000
S02 Fracture of skull and facial bones
0.877 0.123 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.875 0.125 0.000
Z92.3 Personal history of irradiation
0.874 0.126 0.000
Z96.8 Presence of other specified functional implants
0.870 0.130 0.000
C78.0 Secondary malignant neoplasm of lung
0.869 0.131 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.869 0.131 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.868 0.132 0.000
D06 Carcinoma in situ of cervix uteri
0.865 0.135 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.865 0.135 0.000
Z42 Follow-up care involving plastic surgery
0.863 0.137 0.000
C64-C68 Malignant neoplasms of urinary tract
0.863 0.137 0.000
A30-A49 Other bacterial diseases
0.862 0.138 0.000
F41 Other anxiety disorders
0.862 0.138 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.862 0.138 0.000
S50-S59 Injuries to the elbow and forearm
0.861 0.139 0.000
C25 Malignant neoplasm of pancreas
0.860 0.140 0.000
M23.8 Other internal derangements of knee
0.859 0.141 0.000
M17.9 Gonarthrosis, unspecified
0.858 0.142 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.857 0.143 0.000
R56.8 Other and unspecified convulsions
0.854 0.146 0.000
Z93.6 Other artificial openings of urinary tract status
0.853 0.147 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.853 0.147 0.000
C16 Malignant neoplasm of stomach
0.853 0.147 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.852 0.148 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.849 0.151 0.000
Z49 Care involving dialysis
0.847 0.153 0.000
Z45 Adjustment and management of implanted device
0.845 0.155 0.000
Z50 Care involving use of rehabilitation procedures
0.844 0.156 0.000
C20 Malignant neoplasm of rectum
0.843 0.157 0.000
M50-M54 Other dorsopathies
0.841 0.159 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.841 0.159 0.000
E74 Other disorders of carbohydrate metabolism
0.841 0.159 0.000
M25.59 Pain in joint (Site unspecified)
0.840 0.160 0.000
E10 Insulin-dependent diabetes mellitus
0.840 0.160 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.837 0.163 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.835 0.165 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.834 0.166 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.833 0.167 0.000
R53 Malaise and fatigue
0.832 0.168 0.000
L20-L30 Dermatitis and eczema
0.831 0.169 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.828 0.172 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.826 0.174 0.000
C18 Malignant neoplasm of colon
0.825 0.175 0.000
R63 Symptoms and signs concerning food and fluid intake
0.825 0.175 0.000
Z80 Family history of malignant neoplasm
0.823 0.177 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.823 0.177 0.000
F41.2 Mixed anxiety and depressive disorder
0.819 0.181 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.818 0.182 0.000
S01.1 Open wound of eyelid and periocular area
0.817 0.183 0.000
Z83.5 Family history of eye and ear disorders
0.817 0.183 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.813 0.187 0.000
M65-M68 Disorders of synovium and tendon
0.812 0.188 0.000
Z96.6 Presence of orthopaedic joint implants
0.811 0.189 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.811 0.189 0.000
Z43 Attention to artificial openings
0.811 0.189 0.000
S82 Fracture of lower leg, including ankle
0.809 0.191 0.000
G40 Epilepsy
0.809 0.191 0.000
Chapter XX External causes of morbidity and mortality
0.807 0.193 0.000
S06 Intracranial injury
0.807 0.193 0.000
Z93.1 Gastrostomy status
0.806 0.193 0.000
T92 Sequelae of injuries of upper limb
0.806 0.194 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.805 0.195 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.804 0.196 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.803 0.197 0.000
R52 Pain, not elsewhere classified
0.802 0.198 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.802 0.198 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.800 0.200 0.000
T93 Sequelae of injuries of lower limb
0.799 0.200 0.000
E66.0 Obesity due to excess calories
0.798 0.202 0.000
Z98 Other postsurgical states
0.798 0.202 0.000
C80.9 Malignant neoplasm, unspecified
0.798 0.202 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.797 0.203 0.000
D06.9 Cervix, unspecified
0.797 0.203 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.793 0.207 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.792 0.208 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.790 0.210 0.000
F41.1 Generalised anxiety disorder
0.789 0.211 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.789 0.211 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.789 0.211 0.000
Z45.2 Adjustment and management of vascular access device
0.789 0.211 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.788 0.212 0.000
M86-M90 Other osteopathies
0.788 0.212 0.000
T66-T78 Other and unspecified effects of external causes
0.788 0.212 0.000
M24 Other specific joint derangements
0.787 0.213 0.000
Chapter X Diseases of the respiratory system
0.787 0.213 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.785 0.215 0.000
E14 Unspecified diabetes mellitus
0.785 0.215 0.000
Z51.2 Other chemotherapy
0.785 0.215 0.000
Z89.4 Acquired absence of foot and ankle
0.785 0.215 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.784 0.216 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.783 0.217 0.000
N00-N08 Glomerular diseases
0.782 0.218 0.000
Z54 Convalescence
0.782 0.218 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.781 0.219 0.000
T39.1 4-Aminophenol derivatives
0.780 0.220 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.780 0.220 0.000
R57 Shock, not elsewhere classified
0.780 0.220 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.779 0.221 0.000
E78.5 Hyperlipidaemia, unspecified
0.779 0.221 0.000
Z92.8 Personal history of other medical treatment
0.778 0.221 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.778 0.222 0.000
E83.4 Disorders of magnesium metabolism
0.776 0.224 0.000
S01.2 Open wound of nose
0.776 0.224 0.000
C01 Malignant neoplasm of base of tongue
0.775 0.225 0.000
G51 Facial nerve disorders
0.774 0.226 0.000
S32 Fracture of lumbar spine and pelvis
0.774 0.226 0.000
Z51.8 Other specified medical care
0.771 0.229 0.000
Z89.5 Acquired absence of leg at or below knee
0.771 0.229 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.771 0.229 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.770 0.230 0.000
R79 Other abnormal findings of blood chemistry
0.769 0.231 0.000
M25.9 Joint disorder, unspecified
0.768 0.231 0.000
C25.9 Pancreas, unspecified
0.768 0.232 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.767 0.233 0.000
E10.9 Without complications
0.767 0.233 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.766 0.233 0.000
Z80.3 Family history of malignant neoplasm of breast
0.766 0.234 0.000
T87 Complications peculiar to reattachment and amputation
0.766 0.234 0.000
Chapter VII Diseases of the eye and adnexa
0.764 0.236 0.000
R58 Haemorrhage, not elsewhere classified
0.762 0.238 0.000
C77.0 Lymph nodes of head, face and neck
0.760 0.240 0.000
R68 Other general symptoms and signs
0.759 0.241 0.000
M05-M14 Inflammatory polyarthropathies
0.758 0.242 0.000
N25-N29 Other disorders of kidney and ureter
0.758 0.242 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.757 0.243 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.757 0.243 0.000
G43.8 Other migraine
0.756 0.244 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.753 0.247 0.000
E89.0 Postprocedural hypothyroidism
0.752 0.248 0.000
H72 Perforation of tympanic membrane
0.751 0.249 0.000
T79-T79 Certain early complications of trauma
0.751 0.249 0.000
C18.9 Colon, unspecified
0.750 0.250 0.000
M00-M03 Infectious arthropathies
0.749 0.250 0.000
R21 Rash and other nonspecific skin eruption
0.749 0.251 0.000
D09 Carcinoma in situ of other and unspecified sites
0.749 0.251 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.749 0.251 0.000
S10-S19 Injuries to the neck
0.749 0.251 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.748 0.252 0.000
M25.51 Pain in joint (Shoulder region)
0.748 0.252 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.748 0.252 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.747 0.253 0.000
Z96.2 Presence of otological and audiological implants
0.747 0.253 0.000
F99-F99 Unspecified mental disorder
0.746 0.254 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.746 0.254 0.000
R63.0 Anorexia
0.745 0.255 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.744 0.256 0.000
E40-E46 Malnutrition
0.743 0.257 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.743 0.257 0.000
D03.5 Melanoma in situ of trunk
0.743 0.257 0.000
S86 Injury of muscle and tendon at lower leg level
0.742 0.258 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.742 0.258 0.000
Z93.0 Tracheostomy status
0.741 0.259 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.741 0.259 0.000
D04 Carcinoma in situ of skin
0.740 0.260 0.000
T42.1 Iminostilbenes
0.740 0.260 0.000
D50-D53 Nutritional anaemias
0.739 0.261 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.739 0.261 0.000
M25.0 Haemarthrosis
0.738 0.262 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.737 0.263 0.000
M15 Polyarthrosis
0.735 0.265 0.000
T86 Failure and rejection of transplanted organs and tissues
0.734 0.266 0.000
S01.8 Open wound of other parts of head
0.734 0.266 0.000
E14.3 With ophthalmic complications
0.734 0.266 0.000
M25.54 Pain in joint (Hand)
0.733 0.267 0.000
E88 Other metabolic disorders
0.733 0.267 0.000
H73 Other disorders of tympanic membrane
0.732 0.268 0.000
M21 Other acquired deformities of limbs
0.732 0.268 0.000
Z40 Prophylactic surgery
0.731 0.269 0.000
B25-B34 Other viral diseases
0.731 0.269 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.731 0.269 0.000
L30 Other dermatitis
0.731 0.269 0.000
Chapter XXII Codes for special purposes
0.730 0.270 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.730 0.270 0.000
M31 Other necrotising vasculopathies
0.730 0.270 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.729 0.271 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.729 0.271 0.000
M20 Acquired deformities of fingers and toes
0.728 0.272 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.727 0.273 0.000
A49 Bacterial infection of unspecified site
0.727 0.273 0.000
M16 Coxarthrosis [arthrosis of hip]
0.727 0.273 0.000
L27 Dermatitis due to substances taken internally
0.726 0.273 0.000
A41 Other septicaemia
0.726 0.274 0.000
T90 Sequelae of injuries of head
0.726 0.274 0.000
B35-B49 Mycoses
0.725 0.275 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.724 0.276 0.000
Z43.1 Attention to gastrostomy
0.724 0.276 0.000
T43.2 Other and unspecified antidepressants
0.724 0.276 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.723 0.277 0.000
Z92.0 Personal history of contraception
0.723 0.277 0.000
F30-F39 Mood [affective] disorders
0.723 0.277 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.723 0.277 0.000
M22 Disorders of patella
0.723 0.277 0.000
M23.5 Chronic instability of knee
0.722 0.278 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.722 0.278 0.000
Z88.2 Personal history of allergy to sulphonamides
0.720 0.279 0.000
Z49.1 Extracorporeal dialysis
0.719 0.280 0.000
R59.9 Enlarged lymph nodes, unspecified
0.719 0.281 0.000
C16.6 Greater curvature of stomach, unspecified
0.719 0.281 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.718 0.282 0.000
S82.1 Fracture of upper end of tibia
0.718 0.282 0.000
M91-M94 Chondropathies
0.718 0.282 0.000
M25.8 Other specified joint disorders
0.718 0.282 0.000
H60-H62 Diseases of external ear
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
Z51.9 Medical care, unspecified
0.715 0.284 0.000
Z51.6 Desensitisation to allergens
0.715 0.284 0.000
N17-N19 Renal failure
0.716 0.284 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.715 0.285 0.000
G70-G73 Diseases of myoneural junction and muscle
0.714 0.286 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.714 0.286 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.714 0.286 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.714 0.286 0.000
M23.3 Other meniscus derangements
0.713 0.287 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.287 0.000
M34 Systemic sclerosis
0.713 0.287 0.000
M33 Dermatopolymyositis
0.713 0.287 0.000
M32 Systemic lupus erythematosus
0.713 0.287 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.287 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.711 0.288 0.000
Z96.7 Presence of other bone and tendon implants
0.711 0.289 0.000
R52.1 Chronic intractable pain
0.711 0.289 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.290 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.710 0.290 0.000
Z92.9 Personal history of medical treatment, unspecified
0.710 0.290 0.000
Z92.5 Personal history of rehabilitation measures
0.710 0.290 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.710 0.290 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.709 0.290 0.000
R62 Lack of expected normal physiological development
0.709 0.290 0.000
R64 Cachexia
0.709 0.290 0.000
M54 Dorsalgia
0.709 0.291 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.709 0.291 0.000
Z41 Procedures for purposes other than remedying health state
0.709 0.291 0.000
N36 Other disorders of urethra
0.708 0.292 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.708 0.292 0.000
B15-B19 Viral hepatitis
0.707 0.293 0.000
Z89.6 Acquired absence of leg above knee
0.707 0.293 0.000
E85 Amyloidosis
0.707 0.293 0.000
E84 Cystic fibrosis
0.707 0.293 0.000
E79 Disorders of purine and pyrimidine metabolism
0.707 0.293 0.000
E77 Disorders of glycoprotein metabolism
0.707 0.293 0.000
E76 Disorders of glycosaminoglycan metabolism
0.707 0.293 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.707 0.293 0.000
E73 Lactose intolerance
0.707 0.293 0.000
E72 Other disorders of amino-acid metabolism
0.707 0.293 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.707 0.293 0.000
E70 Disorders of aromatic amino-acid metabolism
0.707 0.293 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.707 0.293 0.000
E67 Other hyperalimentation
0.706 0.294 0.000
E68 Sequelae of hyperalimentation
0.706 0.294 0.000
E65 Localised adiposity
0.706 0.294 0.000
S81 Open wound of lower leg
0.705 0.295 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.704 0.295 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.704 0.296 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.704 0.296 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.704 0.296 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.704 0.296 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.704 0.296 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.704 0.296 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.704 0.296 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.704 0.296 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.704 0.296 0.000
T36 Poisoning by systemic antibiotics
0.704 0.296 0.000
G57 Mononeuropathies of lower limb
0.704 0.296 0.000
M51 Other intervertebral disk disorders
0.704 0.296 0.000
Z90.5 Acquired absence of kidney
0.704 0.296 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.703 0.297 0.000
S50 Superficial injury of forearm
0.703 0.297 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.702 0.298 0.000
Z93.2 Ileostomy status
0.702 0.298 0.000
Z90.0 Acquired absence of part of head and neck
0.701 0.299 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.701 0.299 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.700 0.300 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.700 0.300 0.000
C21 Malignant neoplasm of anus and anal canal
0.700 0.300 0.000
C17 Malignant neoplasm of small intestine
0.700 0.300 0.000
C23 Malignant neoplasm of gallbladder
0.700 0.300 0.000
H65 Nonsuppurative otitis media
0.700 0.300 0.000
C77.3 Axillary and upper limb lymph nodes
0.700 0.300 0.000
M23.4 Loose body in knee
0.700 0.300 0.000
H69 Other disorders of Eustachian tube
0.700 0.300 0.000
Z90.3 Acquired absence of part of stomach
0.699 0.301 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.699 0.301 0.000
H80-H83 Diseases of inner ear
0.699 0.301 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.698 0.302 0.000
E66.1 Drug-induced obesity
0.698 0.302 0.000
S08 Traumatic amputation of part of head
0.698 0.302 0.000
S07 Crushing injury of head
0.698 0.302 0.000
S05 Injury of eye and orbit
0.698 0.302 0.000
S04 Injury of cranial nerves
0.698 0.302 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.698 0.302 0.000
S02.2 Fracture of nasal bones
0.697 0.303 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.696 0.304 0.000
Z52 Donors of organs and tissues
0.695 0.305 0.000
B99-B99 Other infectious diseases
0.694 0.306 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.694 0.306 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.694 0.306 0.000
B65-B83 Helminthiases
0.694 0.306 0.000
B50-B64 Protozoal diseases
0.694 0.306 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.694 0.306 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.694 0.306 0.000
A80-A89 Viral infections of the central nervous system
0.694 0.306 0.000
A75-A79 Rickettsioses
0.694 0.306 0.000
A70-A74 Other diseases caused by chlamydiae
0.694 0.306 0.000
A65-A69 Other spirochaetal diseases
0.694 0.306 0.000
A20-A28 Certain zoonotic bacterial diseases
0.694 0.306 0.000
A15-A19 Tuberculosis
0.694 0.306 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.694 0.306 0.000
E50-E64 Other nutritional deficiencies
0.693 0.306 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.693 0.307 0.000
M25.3 Other instability of joint
0.693 0.307 0.000
M25.2 Flail joint
0.693 0.307 0.000
M25.1 Fistula of joint
0.693 0.307 0.000
S02.1 Fracture of base of skull
0.692 0.308 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.692 0.308 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.691 0.309 0.000
Z22 Carrier of infectious disease
0.691 0.309 0.000
S02.4 Fracture of malar and maxillary bones
0.690 0.310 0.000
H90-H95 Other disorders of ear
0.689 0.311 0.000
G62 Other polyneuropathies
0.689 0.311 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.688 0.312 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.688 0.312 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.688 0.312 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.688 0.312 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.688 0.312 0.000
Y86 Sequelae of other accidents
0.688 0.312 0.000
G40.9 Epilepsy, unspecified
0.687 0.313 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.687 0.313 0.000
N10-N16 Renal tubulo-interstitial diseases
0.687 0.313 0.000
C79.2 Secondary malignant neoplasm of skin
0.686 0.314 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.686 0.314 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.686 0.314 0.000
G51.0 Bell's palsy
0.686 0.314 0.000
M25.7 Osteophyte
0.686 0.314 0.000
N35 Urethral stricture
0.685 0.314 0.000
S01.5 Open wound of lip and oral cavity
0.685 0.315 0.000
S01.4 Open wound of cheek and temporomandibular area
0.684 0.316 0.000
L29 Pruritus
0.684 0.316 0.000
M17.1 Other primary gonarthrosis
0.683 0.317 0.000
E83.3 Disorders of phosphorus metabolism
0.683 0.317 0.000
Z98.1 Arthrodesis status
0.682 0.318 0.000
Z93.5 Cystostomy status
0.681 0.319 0.000
H66 Suppurative and unspecified otitis media
0.681 0.319 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.680 0.320 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.680 0.320 0.000
G43.1 Migraine with aura [classical migraine]
0.680 0.320 0.000
N03 Chronic nephritic syndrome
0.680 0.320 0.000
C09 Malignant neoplasm of tonsil
0.679 0.321 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.679 0.321 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.679 0.321 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.679 0.321 0.000
C16.0 Cardia
0.678 0.321 0.000
F80-F89 Disorders of psychological development
0.678 0.322 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.678 0.322 0.000
E83.8 Other disorders of mineral metabolism
0.678 0.322 0.000
E83.2 Disorders of zinc metabolism
0.678 0.322 0.000
E83.0 Disorders of copper metabolism
0.678 0.322 0.000
M23.9 Internal derangement of knee, unspecified
0.677 0.323 0.000
M23.1 Discoid meniscus (congenital)
0.677 0.323 0.000
M23.0 Cystic meniscus
0.677 0.323 0.000
Z90.8 Acquired absence of other organs
0.677 0.323 0.000
M25.58 Pain in joint (Other)
0.676 0.324 0.000
M25.52 Pain in joint (Upper arm)
0.676 0.324 0.000
M17.3 Other posttraumatic gonarthrosis
0.675 0.325 0.000
Z94 Transplanted organ and tissue status
0.675 0.325 0.000
Z83.3 Family history of diabetes mellitus
0.675 0.325 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.674 0.326 0.000
M45-M49 Spondylopathies
0.674 0.326 0.000
S52 Fracture of forearm
0.673 0.327 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.673 0.327 0.000
S20-S29 Injuries to the thorax
0.673 0.327 0.000
C88 Malignant immunoproliferative diseases
0.672 0.328 0.000
N32 Other disorders of bladder
0.672 0.328 0.000
J00-J06 Acute upper respiratory infections
0.672 0.328 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.671 0.329 0.000
Z96.9 Presence of functional implant, unspecified
0.671 0.329 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.671 0.329 0.000
Z96.4 Presence of endocrine implants
0.671 0.329 0.000
Z96.3 Presence of artificial larynx
0.671 0.329 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.671 0.329 0.000
Z97 Presence of other devices
0.670 0.330 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.670 0.330 0.000
G41 Status epilepticus
0.670 0.330 0.000
Z93.9 Artificial opening status, unspecified
0.670 0.330 0.000
Z93.8 Other artificial opening status
0.670 0.330 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.669 0.331 0.000
S70-S79 Injuries to the hip and thigh
0.669 0.331 0.000
M16.0 Primary coxarthrosis, bilateral
0.669 0.331 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.668 0.331 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.668 0.331 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.668 0.331 0.000
F60-F69 Disorders of adult personality and behaviour
0.668 0.331 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.668 0.332 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.668 0.332 0.000
T98 Sequelae of other and unspecified effects of external causes
0.668 0.332 0.000
T95 Sequelae of burns, corrosions and frostbite
0.668 0.332 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.668 0.332 0.000
T91 Sequelae of injuries of neck and trunk
0.668 0.332 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.668 0.332 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.668 0.332 0.000
H53-H54 Visual disturbances and blindness
0.668 0.332 0.000
R81 Glycosuria
0.668 0.332 0.000
S09 Other and unspecified injuries of head
0.668 0.332 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.668 0.332 0.000
Z45.1 Adjustment and management of infusion pump
0.667 0.332 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.667 0.333 0.000
F70-F79 Mental retardation
0.667 0.333 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.667 0.333 0.000
S89 Other and unspecified injuries of lower leg
0.666 0.333 0.000
S88 Traumatic amputation of lower leg
0.666 0.333 0.000
S87 Crushing injury of lower leg
0.666 0.333 0.000
S85 Injury of blood vessels at lower leg level
0.666 0.333 0.000
S84 Injury of nerves at lower leg level
0.666 0.333 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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