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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1296249
log Bayes Factor = 16.014
Chromosome 13   position 112,998,648  (GRCh37) Explore rs1296249 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.998 0.002 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
B95-B98 Bacterial, viral and other infectious agents
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
M45-M49 Spondylopathies
0.993 0.007 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.989 0.011 0.000
M20-M25 Other joint disorders
0.987 0.013 0.000
S00-S09 Injuries to the head
0.987 0.013 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.983 0.017 0.000
Chapter IX Diseases of the circulatory system
0.982 0.018 0.000
F10.2 Dependence syndrome
0.979 0.021 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.976 0.024 0.000
Chapter XXI Factors influencing health status and contact with health services
0.973 0.027 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.970 0.030 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.969 0.031 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.963 0.037 0.000
Chapter X Diseases of the respiratory system
0.958 0.042 0.000
M48 Other spondylopathies
0.957 0.043 0.000
M47 Spondylosis
0.952 0.048 0.000
G40-G47 Episodic and paroxysmal disorders
0.951 0.049 0.000
F10.0 Acute intoxication
0.951 0.049 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.946 0.054 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.944 0.056 0.000
S00 Superficial injury of head
0.938 0.062 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.933 0.067 0.000
M48.0 Spinal stenosis
0.930 0.070 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.929 0.071 0.000
F10.3 Withdrawal state
0.928 0.072 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.917 0.083 0.000
Y83.4 Other reconstructive surgery
0.915 0.085 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.911 0.089 0.000
T81 Complications of procedures, not elsewhere classified
0.907 0.093 0.000
I60-I69 Cerebrovascular diseases
0.902 0.098 0.000
Chapter VII Diseases of the eye and adnexa
0.902 0.098 0.000
F41 Other anxiety disorders
0.899 0.101 0.000
S01 Open wound of head
0.898 0.102 0.000
M48.06 Spinal stenosis (Lumbar region)
0.897 0.103 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.896 0.104 0.000
Z93 Artificial opening status
0.894 0.106 0.000
Y83.8 Other surgical procedures
0.892 0.108 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.887 0.113 0.000
M25 Other joint disorders, not elsewhere classified
0.885 0.115 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.881 0.119 0.000
M35 Other systemic involvement of connective tissue
0.879 0.121 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.873 0.127 0.000
J95-J99 Other diseases of the respiratory system
0.872 0.128 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.870 0.130 0.000
G43 Migraine
0.863 0.137 0.000
M47.9 Spondylosis, unspecified
0.862 0.138 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.859 0.141 0.000
Z92 Personal history of medical treatment
0.858 0.142 0.000
Z50 Care involving use of rehabilitation procedures
0.858 0.142 0.000
Z93.1 Gastrostomy status
0.858 0.142 0.000
G90-G99 Other disorders of the nervous system
0.855 0.145 0.000
S00.9 Superficial injury of head, part unspecified
0.851 0.149 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.850 0.150 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.845 0.155 0.000
A30-A49 Other bacterial diseases
0.845 0.155 0.000
Z85 Personal history of malignant neoplasm
0.842 0.158 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.841 0.159 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.837 0.163 0.000
I77 Other disorders of arteries and arterioles
0.836 0.164 0.000
M40-M43 Deforming dorsopathies
0.835 0.165 0.000
J30-J39 Other diseases of upper respiratory tract
0.833 0.167 0.000
M47.8 Other spondylosis
0.833 0.167 0.000
Z43 Attention to artificial openings
0.830 0.170 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.829 0.171 0.000
G40 Epilepsy
0.827 0.173 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.824 0.176 0.000
M21 Other acquired deformities of limbs
0.823 0.177 0.000
M86-M90 Other osteopathies
0.823 0.177 0.000
M25.7 Osteophyte
0.823 0.177 0.000
Z80 Family history of malignant neoplasm
0.822 0.178 0.000
S90-S99 Injuries to the ankle and foot
0.821 0.179 0.000
F43 Reaction to severe stress, and adjustment disorders
0.820 0.180 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.820 0.180 0.000
Z86 Personal history of certain other diseases
0.820 0.180 0.000
Chapter XIV Diseases of the genitourinary system
0.816 0.184 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.811 0.189 0.000
S00.0 Superficial injury of scalp
0.810 0.190 0.000
M20 Acquired deformities of fingers and toes
0.810 0.190 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.809 0.191 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.807 0.193 0.000
M23 Internal derangement of knee
0.806 0.194 0.000
F11 Mental and behavioural disorders due to use of opioids
0.805 0.195 0.000
I69 Sequelae of cerebrovascular disease
0.804 0.196 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.802 0.198 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.801 0.199 0.000
G56 Mononeuropathies of upper limb
0.800 0.200 0.000
G43.9 Migraine, unspecified
0.799 0.201 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.799 0.201 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.798 0.202 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.794 0.206 0.000
I67 Other cerebrovascular diseases
0.793 0.207 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.793 0.207 0.000
Chapter XXII Codes for special purposes
0.791 0.209 0.000
M91-M94 Chondropathies
0.790 0.210 0.000
S50-S59 Injuries to the elbow and forearm
0.790 0.210 0.000
I05-I09 Chronic rheumatic heart diseases
0.790 0.210 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.790 0.210 0.000
J20-J22 Other acute lower respiratory infections
0.788 0.212 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.788 0.212 0.000
M31 Other necrotising vasculopathies
0.788 0.212 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.786 0.214 0.000
B35-B49 Mycoses
0.785 0.215 0.000
I73 Other peripheral vascular diseases
0.785 0.215 0.000
Z89 Acquired absence of limb
0.783 0.217 0.000
Z86.4 Personal history of psychoactive substance abuse
0.782 0.218 0.000
M60-M63 Disorders of muscles
0.781 0.219 0.000
Z48 Other surgical follow-up care
0.781 0.219 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.779 0.221 0.000
M15-M19 Arthrosis
0.778 0.222 0.000
S40-S49 Injuries to the shoulder and upper arm
0.777 0.223 0.000
F41.2 Mixed anxiety and depressive disorder
0.777 0.223 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.777 0.223 0.000
G50 Disorders of trigeminal nerve
0.776 0.224 0.000
M47.82 Other spondylosis (Cervical region)
0.775 0.225 0.000
S02 Fracture of skull and facial bones
0.774 0.226 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.773 0.227 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.771 0.229 0.000
G20-G26 Extrapyramidal and movement disorders
0.771 0.229 0.000
Z97 Presence of other devices
0.771 0.229 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.770 0.230 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.770 0.230 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.769 0.231 0.000
Y84.2 Radiological procedure and radiotherapy
0.768 0.232 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.767 0.233 0.000
G93 Other disorders of brain
0.767 0.233 0.000
Z30 Contraceptive management
0.767 0.233 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.766 0.234 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.766 0.234 0.000
M65-M68 Disorders of synovium and tendon
0.766 0.234 0.000
I95 Hypotension
0.766 0.234 0.000
I78 Diseases of capillaries
0.762 0.238 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.760 0.240 0.000
M35.0 Sicca syndrome [Sjogren]
0.759 0.241 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.758 0.242 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.757 0.243 0.000
W00-W19 Falls
0.756 0.243 0.000
A41 Other septicaemia
0.755 0.245 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.755 0.245 0.000
S09 Other and unspecified injuries of head
0.754 0.246 0.000
M47.2 Other spondylosis with radiculopathy
0.753 0.247 0.000
S60-S69 Injuries to the wrist and hand
0.753 0.247 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.753 0.247 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.752 0.248 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.752 0.248 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.751 0.249 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.750 0.250 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.749 0.251 0.000
M46 Other inflammatory spondylopathies
0.749 0.251 0.000
Y83.3 Surgical operation with formation of external stoma
0.749 0.251 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.749 0.251 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.748 0.252 0.000
F40 Phobic anxiety disorders
0.748 0.252 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.747 0.253 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.747 0.253 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.746 0.254 0.000
Z33 Pregnant state, incidental
0.746 0.254 0.000
Chapter VIII Diseases of the ear and mastoid process
0.745 0.255 0.000
H55-H59 Other disorders of eye and adnexa
0.744 0.256 0.000
G47 Sleep disorders
0.742 0.258 0.000
F80-F89 Disorders of psychological development
0.742 0.258 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.739 0.261 0.000
S01.2 Open wound of nose
0.739 0.261 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.739 0.261 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.738 0.262 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.738 0.262 0.000
Z30.2 Sterilisation
0.738 0.262 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.737 0.263 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.737 0.263 0.000
Chapter XI Diseases of the digestive system
0.737 0.263 0.000
M48.09 Spinal stenosis (Site unspecified)
0.736 0.263 0.000
G81 Hemiplegia
0.736 0.264 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.736 0.264 0.000
Z94 Transplanted organ and tissue status
0.735 0.265 0.000
T66-T78 Other and unspecified effects of external causes
0.734 0.266 0.000
M70-M79 Other soft tissue disorders
0.734 0.266 0.000
I70 Atherosclerosis
0.729 0.271 0.000
N99-N99 Other disorders of the genitourinary system
0.729 0.271 0.000
S06 Intracranial injury
0.729 0.271 0.000
M05-M14 Inflammatory polyarthropathies
0.728 0.272 0.000
B15-B19 Viral hepatitis
0.727 0.273 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.727 0.273 0.000
Z81 Family history of mental and behavioural disorders
0.727 0.273 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.727 0.273 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.725 0.275 0.000
M25.74 Osteophyte (Hand)
0.725 0.275 0.000
Y83.9 Surgical procedure, unspecified
0.723 0.277 0.000
S20-S29 Injuries to the thorax
0.723 0.277 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.723 0.277 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.723 0.277 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.722 0.278 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.722 0.278 0.000
F10.1 Harmful use
0.720 0.280 0.000
S01.8 Open wound of other parts of head
0.719 0.281 0.000
H43-H45 Disorders of vitreous body and globe
0.718 0.282 0.000
S01.3 Open wound of ear
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
M35.3 Polymyalgia rheumatica
0.717 0.283 0.000
F99-F99 Unspecified mental disorder
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F60-F69 Disorders of adult personality and behaviour
0.717 0.283 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.284 0.000
T86 Failure and rejection of transplanted organs and tissues
0.716 0.284 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.284 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.715 0.285 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.715 0.285 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.715 0.285 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.715 0.285 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.715 0.285 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.715 0.285 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.715 0.285 0.000
B99-B99 Other infectious diseases
0.715 0.285 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B65-B83 Helminthiases
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A80-A89 Viral infections of the central nervous system
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.715 0.285 0.000
F10.9 Unspecified mental and behavioural disorder
0.715 0.285 0.000
F10.8 Other mental and behavioural disorders
0.715 0.285 0.000
F10.7 Residual and late-onset psychotic disorder
0.715 0.285 0.000
F10.6 Amnesic syndrome
0.715 0.285 0.000
F10.5 Psychotic disorder
0.715 0.285 0.000
F10.4 Withdrawal state with delirium
0.715 0.285 0.000
G70-G73 Diseases of myoneural junction and muscle
0.715 0.285 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.715 0.285 0.000
V10-V19 Pedal cyclist injured in transport accident
0.714 0.286 0.000
H53-H54 Visual disturbances and blindness
0.714 0.286 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.713 0.287 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.712 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.287 0.000
Y10-Y34 Event of undetermined intent
0.712 0.287 0.000
Y00-Y09 Assault
0.712 0.287 0.000
X85-X99 Assault
0.712 0.287 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.287 0.000
X50-X57 Overexertion, travel and privation
0.712 0.287 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.712 0.287 0.000
X30-X39 Exposure to forces of nature
0.712 0.287 0.000
X20-X29 Contact with venomous animals and plants
0.712 0.287 0.000
X10-X19 Contact with heat and hot substances
0.712 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.287 0.000
W75-W84 Other accidental threats to breathing
0.712 0.287 0.000
W65-W74 Accidental drowning and submersion
0.712 0.287 0.000
W50-W64 Exposure to animate mechanical forces
0.712 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.287 0.000
V95-V97 Air and space transport accidents
0.712 0.287 0.000
V90-V94 Water transport accidents
0.712 0.287 0.000
V80-V89 Other land transport accidents
0.712 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.287 0.000
V40-V49 Car occupant injured in transport accident
0.712 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.287 0.000
V20-V29 Motorcycle rider injured in transport accident
0.712 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.287 0.000
S00.8 Superficial injury of other parts of head
0.712 0.288 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.712 0.288 0.000
M49 Spondylopathies in diseases classified elsewhere
0.712 0.288 0.000
M45 Ankylosing spondylitis
0.712 0.288 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.712 0.288 0.000
I67.8 Other specified cerebrovascular diseases
0.711 0.289 0.000
I77.1 Stricture of artery
0.711 0.289 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.711 0.289 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.711 0.289 0.000
G56.0 Carpal tunnel syndrome
0.710 0.290 0.000
S01.5 Open wound of lip and oral cavity
0.710 0.290 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.710 0.290 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.709 0.291 0.000
Z93.2 Ileostomy status
0.709 0.291 0.000
I95.9 Hypotension, unspecified
0.709 0.291 0.000
J40-J47 Chronic lower respiratory diseases
0.709 0.291 0.000
K50-K52 Noninfective enteritis and colitis
0.708 0.292 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.708 0.292 0.000
G44 Other headache syndromes
0.708 0.292 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.708 0.292 0.000
M34 Systemic sclerosis
0.708 0.292 0.000
M33 Dermatopolymyositis
0.708 0.292 0.000
M32 Systemic lupus erythematosus
0.708 0.292 0.000
M30 Polyarteritis nodosa and related conditions
0.708 0.292 0.000
S08 Traumatic amputation of part of head
0.708 0.292 0.000
S07 Crushing injury of head
0.708 0.292 0.000
S05 Injury of eye and orbit
0.708 0.292 0.000
S04 Injury of cranial nerves
0.708 0.292 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.708 0.292 0.000
X60-X84 Intentional self-harm
0.707 0.292 0.000
Z92.8 Personal history of other medical treatment
0.706 0.294 0.000
M41 Scoliosis
0.705 0.295 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.705 0.295 0.000
Y83.5 Amputation of limb(s)
0.705 0.295 0.000
Y83.0 Surgical operation with transplant of whole organ
0.705 0.295 0.000
B25-B34 Other viral diseases
0.704 0.296 0.000
Z43.1 Attention to gastrostomy
0.704 0.296 0.000
I00-I02 Acute rheumatic fever
0.704 0.296 0.000
J98 Other respiratory disorders
0.704 0.296 0.000
G58 Other mononeuropathies
0.703 0.297 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.702 0.298 0.000
M80-M85 Disorders of bone density and structure
0.702 0.298 0.000
M24 Other specific joint derangements
0.702 0.298 0.000
F30-F39 Mood [affective] disorders
0.701 0.298 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.701 0.299 0.000
Z50.1 Other physical therapy
0.701 0.299 0.000
Z85.6 Personal history of leukaemia
0.700 0.300 0.000
N30-N39 Other diseases of urinary system
0.700 0.300 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.699 0.300 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.699 0.300 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.699 0.300 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.699 0.300 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.699 0.300 0.000
M48.02 Spinal stenosis (Cervical region)
0.699 0.301 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.697 0.303 0.000
W20-W49 Exposure to inanimate mechanical forces
0.695 0.305 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.695 0.305 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.695 0.305 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.695 0.305 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.695 0.305 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.695 0.305 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.695 0.305 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.695 0.305 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.695 0.305 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.695 0.305 0.000
Z43.0 Attention to tracheostomy
0.695 0.305 0.000
M23.3 Other meniscus derangements
0.694 0.306 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.694 0.306 0.000
K51 Ulcerative colitis
0.693 0.307 0.000
F41.1 Generalised anxiety disorder
0.692 0.308 0.000
M21.0 Valgus deformity, not elsewhere classified
0.691 0.309 0.000
F48 Other neurotic disorders
0.690 0.310 0.000
F45 Somatoform disorders
0.690 0.310 0.000
F44 Dissociative [conversion] disorders
0.690 0.310 0.000
F42 Obsessive-compulsive disorder
0.690 0.310 0.000
M25.8 Other specified joint disorders
0.689 0.311 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.687 0.313 0.000
M48.9 Spondylopathy, unspecified
0.686 0.314 0.000
M48.8 Other specified spondylopathies
0.686 0.314 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.686 0.314 0.000
M48.4 Fatigue fracture of vertebra
0.686 0.314 0.000
M48.3 Traumatic spondylopathy
0.686 0.314 0.000
M48.2 Kissing spine
0.686 0.314 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.686 0.314 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.686 0.314 0.000
S70-S79 Injuries to the hip and thigh
0.686 0.314 0.000
M47.1 Other spondylosis with myelopathy
0.683 0.317 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.683 0.317 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.683 0.317 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.682 0.318 0.000
G41 Status epilepticus
0.682 0.318 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.682 0.318 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.681 0.319 0.000
M16 Coxarthrosis [arthrosis of hip]
0.681 0.319 0.000
M89 Other disorders of bone
0.680 0.320 0.000
J00-J06 Acute upper respiratory infections
0.680 0.320 0.000
F43.2 Adjustment disorders
0.679 0.320 0.000
S80-S89 Injuries to the knee and lower leg
0.679 0.321 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.678 0.322 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.677 0.323 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.677 0.323 0.000
T85.2 Mechanical complication of intraocular lens
0.677 0.323 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.677 0.323 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.677 0.323 0.000
J36 Peritonsillar abscess
0.676 0.323 0.000
Z93.0 Tracheostomy status
0.676 0.324 0.000
I74 Arterial embolism and thrombosis
0.676 0.324 0.000
Y84.6 Urinary catheterisation
0.675 0.324 0.000
Z93.5 Cystostomy status
0.675 0.324 0.000
Chapter II Neoplasms
0.675 0.325 0.000
G50.0 Trigeminal neuralgia
0.675 0.325 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.675 0.325 0.000
T98 Sequelae of other and unspecified effects of external causes
0.675 0.325 0.000
Z50.2 Alcohol rehabilitation
0.674 0.326 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.673 0.327 0.000
K51.9 Ulcerative colitis, unspecified
0.673 0.327 0.000
Z39 Postpartum care and examination
0.672 0.328 0.000
S00.7 Multiple superficial injuries of head
0.672 0.328 0.000
S00.5 Superficial injury of lip and oral cavity
0.672 0.328 0.000
S00.4 Superficial injury of ear
0.672 0.328 0.000
S00.3 Superficial injury of nose
0.672 0.328 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.672 0.328 0.000
S00.1 Contusion of eyelid and periocular area
0.672 0.328 0.000
Z48.8 Other specified surgical follow-up care
0.672 0.328 0.000
F41.9 Anxiety disorder, unspecified
0.669 0.331 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.669 0.331 0.000
I72 Other aneurysm
0.669 0.331 0.000
I65.2 Occlusion and stenosis of carotid artery
0.669 0.331 0.000
G30-G32 Other degenerative diseases of the nervous system
0.667 0.333 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.667 0.333 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.667 0.333 0.000
M48.04 Spinal stenosis (Thoracic region)
0.667 0.333 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.667 0.333 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.667 0.333 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.667 0.333 0.000
F11.2 Dependence syndrome
0.667 0.333 0.000
J22 Unspecified acute lower respiratory infection
0.667 0.333 0.000
J39 Other diseases of upper respiratory tract
0.667 0.333 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.667 0.333 0.000
Z84 Family history of other conditions
0.666 0.334 0.000
Z50.0 Cardiac rehabilitation
0.666 0.334 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.666 0.334 0.000
Z43.2 Attention to ileostomy
0.665 0.335 0.000
Z92.0 Personal history of contraception
0.664 0.336 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.664 0.336 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.663 0.337 0.000
G51 Facial nerve disorders
0.663 0.337 0.000
M25.77 Osteophyte (Ankle and foot)
0.662 0.338 0.000
S92 Fracture of foot, except ankle
0.662 0.338 0.000
M25.76 Osteophyte (Lower leg)
0.661 0.339 0.000
J90-J94 Other diseases of pleura
0.660 0.340 0.000
S01.1 Open wound of eyelid and periocular area
0.659 0.341 0.000
H40-H42 Glaucoma
0.659 0.341 0.000
G81.9 Hemiplegia, unspecified
0.659 0.341 0.000
I80 Phlebitis and thrombophlebitis
0.658 0.342 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.658 0.342 0.000
G54 Nerve root and plexus disorders
0.658 0.342 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.658 0.342 0.000
G52 Disorders of other cranial nerves
0.658 0.342 0.000
N32 Other disorders of bladder
0.656 0.344 0.000
K70-K77 Diseases of liver
0.655 0.345 0.000
Z22 Carrier of infectious disease
0.654 0.346 0.000
M20.5 Other deformities of toe(s) (acquired)
0.654 0.346 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.653 0.346 0.000
N25-N29 Other disorders of kidney and ureter
0.653 0.347 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.652 0.347 0.000
F43.1 Posttraumatic stress disorder
0.652 0.348 0.000
N40-N51 Diseases of male genital organs
0.651 0.349 0.000
Z36 Antenatal screening
0.651 0.349 0.000
T81.9 Unspecified complication of procedure
0.650 0.350 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.650 0.350 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.650 0.350 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.650 0.350 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.650 0.350 0.000
G93.6 Cerebral oedema
0.650 0.350 0.000
S01.9 Open wound of head, part unspecified
0.649 0.351 0.000
N60-N64 Disorders of breast
0.649 0.351 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.648 0.352 0.000
B35 Dermatophytosis
0.648 0.352 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.647 0.353 0.000
I73.9 Peripheral vascular disease, unspecified
0.647 0.353 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.647 0.353 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.647 0.353 0.000
J98.4 Other disorders of lung
0.646 0.354 0.000
H10-H13 Disorders of conjunctiva
0.646 0.354 0.000
F41.8 Other specified anxiety disorders
0.645 0.355 0.000
F41.3 Other mixed anxiety disorders
0.645 0.355 0.000
M31.6 Other giant cell arteritis
0.645 0.355 0.000
M18 Arthrosis of first carpometacarpal joint
0.644 0.356 0.000
N00-N08 Glomerular diseases
0.644 0.356 0.000
S01.7 Multiple open wounds of head
0.644 0.356 0.000
S01.4 Open wound of cheek and temporomandibular area
0.644 0.356 0.000
M20.1 Hallux valgus (acquired)
0.643 0.357 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.643 0.357 0.000
Y40 Systemic antibiotics
0.641 0.358 0.000
Z89.6 Acquired absence of leg above knee
0.641 0.358 0.000
Z93.9 Artificial opening status, unspecified
0.641 0.359 0.000
Z93.8 Other artificial opening status
0.641 0.359 0.000
G93.4 Encephalopathy, unspecified
0.641 0.359 0.000
M94 Other disorders of cartilage
0.640 0.360 0.000
A00-A09 Intestinal infectious diseases
0.640 0.360 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.639 0.361 0.000
I78.1 Naevus, nonneoplastic
0.639 0.361 0.000
J38.7 Other diseases of larynx
0.639 0.361 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.636 0.364 0.000
M16.1 Other primary coxarthrosis
0.636 0.364 0.000
Z54 Convalescence
0.636 0.364 0.000
Z52 Donors of organs and tissues
0.636 0.364 0.000
Z49 Care involving dialysis
0.636 0.364 0.000
Z44 Fitting and adjustment of external prosthetic device
0.636 0.364 0.000
J81 Pulmonary oedema
0.635 0.365 0.000
Z97.4 Presence of external hearing-aid
0.635 0.365 0.000
S90 Superficial injury of ankle and foot
0.634 0.365 0.000
M25.9 Joint disorder, unspecified
0.634 0.366 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.634 0.366 0.000
M25.3 Other instability of joint
0.634 0.366 0.000
M25.2 Flail joint
0.634 0.366 0.000
M25.1 Fistula of joint
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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