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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13152134
log Bayes Factor = 12.3669
Chromosome 4   position 156,465,403  (GRCh37) Explore rs13152134 on Ensembl!
Variant rs13152134 is part of Cluster X0111

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.997 0.003 0.000
G40-G47 Episodic and paroxysmal disorders
0.997 0.003 0.000
E11 Non-insulin-dependent diabetes mellitus
0.995 0.005 0.000
J40-J47 Chronic lower respiratory diseases
0.995 0.005 0.000
G47 Sleep disorders
0.994 0.006 0.000
E11.9 Without complications
0.994 0.006 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.988 0.012 0.000
G47.3 Sleep apnoea
0.988 0.012 0.000
S60-S69 Injuries to the wrist and hand
0.988 0.012 0.000
J44 Other chronic obstructive pulmonary disease
0.978 0.022 0.000
J09-J18 Influenza and pneumonia
0.964 0.036 0.000
E70-E90 Metabolic disorders
0.962 0.038 0.000
S00-S09 Injuries to the head
0.959 0.041 0.000
J47 Bronchiectasis
0.954 0.046 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.945 0.055 0.000
Chapter I Certain infectious and parasitic diseases
0.941 0.059 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.939 0.061 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.929 0.071 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.928 0.072 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.926 0.074 0.000
J00-J06 Acute upper respiratory infections
0.926 0.074 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.922 0.078 0.000
D50-D53 Nutritional anaemias
0.921 0.079 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.913 0.087 0.000
S00 Superficial injury of head
0.912 0.088 0.000
E00-E07 Disorders of thyroid gland
0.902 0.098 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.899 0.100 0.000
D51 Vitamin B12 deficiency anaemia
0.896 0.104 0.000
G47.9 Sleep disorder, unspecified
0.891 0.109 0.000
E83 Disorders of mineral metabolism
0.890 0.110 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.888 0.112 0.000
Y95 Nosocomial condition
0.885 0.115 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.882 0.118 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.882 0.118 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.877 0.123 0.000
B25-B34 Other viral diseases
0.873 0.127 0.000
J43 Emphysema
0.870 0.130 0.000
Chapter V Mental and behavioural disorders
0.868 0.132 0.000
E16 Other disorders of pancreatic internal secretion
0.867 0.133 0.000
A30-A49 Other bacterial diseases
0.865 0.135 0.000
S00.8 Superficial injury of other parts of head
0.862 0.138 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.860 0.140 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.859 0.141 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.858 0.142 0.000
E20-E35 Disorders of other endocrine glands
0.855 0.145 0.000
Y57 Other and unspecified drugs and medicaments
0.853 0.147 0.000
S64 Injury of nerves at wrist and hand level
0.852 0.148 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.852 0.148 0.000
Y86 Sequelae of other accidents
0.852 0.148 0.000
G43 Migraine
0.852 0.148 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.851 0.149 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.844 0.156 0.000
Chapter VIII Diseases of the ear and mastoid process
0.844 0.156 0.000
J03 Acute tonsillitis
0.837 0.163 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.836 0.164 0.000
T39.0 Salicylates
0.835 0.165 0.000
J60-J70 Lung diseases due to external agents
0.833 0.167 0.000
E04 Other non-toxic goitre
0.829 0.171 0.000
S62 Fracture at wrist and hand level
0.829 0.171 0.000
E16.2 Hypoglycaemia, unspecified
0.827 0.173 0.000
B34 Viral infection of unspecified site
0.825 0.175 0.000
S61 Open wound of wrist and hand
0.824 0.176 0.000
S09 Other and unspecified injuries of head
0.824 0.176 0.000
E87.2 Acidosis
0.824 0.176 0.000
J18 Pneumonia, organism unspecified
0.822 0.178 0.000
G90-G99 Other disorders of the nervous system
0.821 0.179 0.000
E10 Insulin-dependent diabetes mellitus
0.819 0.181 0.000
E50-E64 Other nutritional deficiencies
0.817 0.182 0.000
T91 Sequelae of injuries of neck and trunk
0.817 0.183 0.000
E88 Other metabolic disorders
0.812 0.188 0.000
G30-G32 Other degenerative diseases of the nervous system
0.811 0.189 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.809 0.191 0.000
J30-J39 Other diseases of upper respiratory tract
0.804 0.196 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.800 0.200 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.798 0.202 0.000
T39.1 4-Aminophenol derivatives
0.798 0.202 0.000
A41 Other septicaemia
0.796 0.204 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.794 0.206 0.000
E11.6 With other specified complications
0.793 0.207 0.000
B34.9 Viral infection, unspecified
0.791 0.209 0.000
G20-G26 Extrapyramidal and movement disorders
0.789 0.211 0.000
E83.1 Disorders of iron metabolism
0.789 0.211 0.000
Y57.9 Drug or medicament, unspecified
0.785 0.215 0.000
S80-S89 Injuries to the knee and lower leg
0.784 0.216 0.000
S65 Injury of blood vessels at wrist and hand level
0.784 0.216 0.000
J95-J99 Other diseases of the respiratory system
0.782 0.218 0.000
S10-S19 Injuries to the neck
0.781 0.219 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.780 0.220 0.000
J11 Influenza, virus not identified
0.778 0.222 0.000
S06 Intracranial injury
0.775 0.225 0.000
E11.1 With ketoacidosis
0.775 0.225 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.773 0.227 0.000
J40 Bronchitis, not specified as acute or chronic
0.773 0.227 0.000
Chapter IX Diseases of the circulatory system
0.773 0.227 0.000
J03.9 Acute tonsillitis, unspecified
0.773 0.227 0.000
Y85 Sequelae of transport accidents
0.770 0.229 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.770 0.230 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.769 0.231 0.000
S40-S49 Injuries to the shoulder and upper arm
0.769 0.231 0.000
G41 Status epilepticus
0.768 0.232 0.000
E04.1 Non-toxic single thyroid nodule
0.767 0.233 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.767 0.233 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.765 0.235 0.000
T43.2 Other and unspecified antidepressants
0.763 0.237 0.000
Y40 Systemic antibiotics
0.763 0.237 0.000
H80-H83 Diseases of inner ear
0.762 0.238 0.000
E11.4 With neurological complications
0.762 0.238 0.000
E83.4 Disorders of magnesium metabolism
0.761 0.239 0.000
G43.9 Migraine, unspecified
0.758 0.242 0.000
Chapter VII Diseases of the eye and adnexa
0.758 0.242 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.757 0.242 0.000
T66-T78 Other and unspecified effects of external causes
0.756 0.244 0.000
E87.6 Hypokalaemia
0.755 0.245 0.000
J01 Acute sinusitis
0.755 0.245 0.000
S64.4 Injury of digital nerve of other finger
0.755 0.245 0.000
T18 Foreign body in alimentary tract
0.755 0.245 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.754 0.246 0.000
S00.0 Superficial injury of scalp
0.754 0.246 0.000
J18.9 Pneumonia, unspecified
0.754 0.246 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.754 0.246 0.000
E73 Lactose intolerance
0.754 0.246 0.000
J30 Vasomotor and allergic rhinitis
0.748 0.252 0.000
S69 Other and unspecified injuries of wrist and hand
0.748 0.252 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.745 0.255 0.000
X50-X57 Overexertion, travel and privation
0.745 0.255 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.744 0.256 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.742 0.258 0.000
W20-W49 Exposure to inanimate mechanical forces
0.741 0.259 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.740 0.260 0.000
G56 Mononeuropathies of upper limb
0.739 0.261 0.000
J43.2 Centrilobular emphysema
0.739 0.261 0.000
T90 Sequelae of injuries of head
0.738 0.262 0.000
G40 Epilepsy
0.737 0.263 0.000
Chapter XXII Codes for special purposes
0.734 0.266 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.733 0.267 0.000
Chapter XIV Diseases of the genitourinary system
0.732 0.268 0.000
E83.3 Disorders of phosphorus metabolism
0.732 0.268 0.000
J69 Pneumonitis due to solids and liquids
0.730 0.270 0.000
E87.0 Hyperosmolality and hypernatraemia
0.730 0.270 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.730 0.270 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.728 0.272 0.000
S09.9 Unspecified injury of head
0.727 0.273 0.000
H81 Disorders of vestibular function
0.726 0.274 0.000
D50 Iron deficiency anaemia
0.725 0.275 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.725 0.275 0.000
I95 Hypotension
0.725 0.275 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.722 0.277 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.722 0.278 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.722 0.278 0.000
S67 Crushing injury of wrist and hand
0.721 0.279 0.000
E40-E46 Malnutrition
0.720 0.280 0.000
J31.0 Chronic rhinitis
0.718 0.282 0.000
B65-B83 Helminthiases
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.717 0.283 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.717 0.283 0.000
N17-N19 Renal failure
0.717 0.283 0.000
E13 Other specified diabetes mellitus
0.715 0.285 0.000
E12 Malnutrition-related diabetes mellitus
0.715 0.285 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.715 0.285 0.000
S70-S79 Injuries to the hip and thigh
0.714 0.286 0.000
E11.8 With unspecified complications
0.713 0.286 0.000
E11.7 With multiple complications
0.713 0.286 0.000
E11.2 With renal complications
0.713 0.286 0.000
E11.0 With coma
0.713 0.286 0.000
J41 Simple and mucopurulent chronic bronchitis
0.713 0.287 0.000
F99-F99 Unspecified mental disorder
0.713 0.287 0.000
G47.8 Other sleep disorders
0.713 0.287 0.000
G47.4 Narcolepsy and cataplexy
0.713 0.287 0.000
G47.2 Disorders of the sleep-wake schedule
0.713 0.287 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.713 0.287 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.713 0.287 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.712 0.288 0.000
T91.3 Sequelae of injury of spinal cord
0.710 0.290 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.709 0.291 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.709 0.291 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.709 0.291 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.709 0.291 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.709 0.291 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.709 0.291 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.709 0.291 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.709 0.291 0.000
T36 Poisoning by systemic antibiotics
0.709 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
W50-W64 Exposure to animate mechanical forces
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
G70-G73 Diseases of myoneural junction and muscle
0.708 0.292 0.000
S60 Superficial injury of wrist and hand
0.708 0.292 0.000
Y52 Agents primarily affecting the cardiovascular system
0.708 0.292 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.707 0.293 0.000
I95.9 Hypotension, unspecified
0.705 0.295 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.705 0.295 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.704 0.296 0.000
D60-D64 Aplastic and other anaemias
0.704 0.296 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.703 0.296 0.000
J43.9 Emphysema, unspecified
0.703 0.297 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.702 0.297 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.702 0.298 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.702 0.298 0.000
J30.1 Allergic rhinitis due to pollen
0.702 0.298 0.000
H81.0 Meniere's disease
0.701 0.299 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.701 0.299 0.000
E29 Testicular dysfunction
0.700 0.300 0.000
E05.9 Thyrotoxicosis, unspecified
0.700 0.300 0.000
T51 Toxic effect of alcohol
0.699 0.301 0.000
B35-B49 Mycoses
0.699 0.301 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.698 0.302 0.000
N18 Chronic renal failure
0.694 0.306 0.000
D52 Folate deficiency anaemia
0.692 0.308 0.000
J17 Pneumonia in diseases classified elsewhere
0.691 0.309 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.691 0.309 0.000
J12 Viral pneumonia, not elsewhere classified
0.691 0.309 0.000
J10 Influenza due to identified influenza virus
0.691 0.309 0.000
J14 Pneumonia due to Haemophilus influenzae
0.691 0.309 0.000
J09 Influenza due to certain identified influenza virus
0.691 0.309 0.000
Y43 Primarily systemic agents
0.690 0.310 0.000
E85 Amyloidosis
0.690 0.310 0.000
E84 Cystic fibrosis
0.690 0.310 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.690 0.310 0.000
E79 Disorders of purine and pyrimidine metabolism
0.690 0.310 0.000
E77 Disorders of glycoprotein metabolism
0.690 0.310 0.000
E76 Disorders of glycosaminoglycan metabolism
0.690 0.310 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.690 0.310 0.000
E74 Other disorders of carbohydrate metabolism
0.690 0.310 0.000
E72 Other disorders of amino-acid metabolism
0.690 0.310 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.690 0.310 0.000
E70 Disorders of aromatic amino-acid metabolism
0.690 0.310 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.690 0.310 0.000
G56.2 Lesion of ulnar nerve
0.690 0.310 0.000
Y44 Agents primarily affecting blood constituents
0.689 0.311 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.688 0.312 0.000
S08 Traumatic amputation of part of head
0.687 0.312 0.000
S07 Crushing injury of head
0.687 0.312 0.000
S05 Injury of eye and orbit
0.687 0.312 0.000
S04 Injury of cranial nerves
0.687 0.312 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.687 0.312 0.000
E23 Hypofunction and other disorders of pituitary gland
0.687 0.313 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.687 0.313 0.000
E04.9 Non-toxic goitre, unspecified
0.685 0.315 0.000
S68 Traumatic amputation of wrist and hand
0.684 0.315 0.000
V20-V29 Motorcycle rider injured in transport accident
0.683 0.317 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.682 0.318 0.000
M45-M49 Spondylopathies
0.682 0.318 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.682 0.318 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.681 0.319 0.000
E86 Volume depletion
0.681 0.319 0.000
X60-X84 Intentional self-harm
0.681 0.319 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.680 0.320 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.680 0.320 0.000
S89 Other and unspecified injuries of lower leg
0.680 0.320 0.000
T18.1 Foreign body in oesophagus
0.680 0.320 0.000
S02 Fracture of skull and facial bones
0.678 0.322 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.678 0.322 0.000
D55-D59 Haemolytic anaemias
0.678 0.322 0.000
A80-A89 Viral infections of the central nervous system
0.678 0.322 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.677 0.323 0.000
S90-S99 Injuries to the ankle and foot
0.676 0.324 0.000
B99-B99 Other infectious diseases
0.674 0.325 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.674 0.325 0.000
B50-B64 Protozoal diseases
0.674 0.325 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.674 0.325 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.674 0.325 0.000
A75-A79 Rickettsioses
0.674 0.325 0.000
A70-A74 Other diseases caused by chlamydiae
0.674 0.325 0.000
A65-A69 Other spirochaetal diseases
0.674 0.325 0.000
A20-A28 Certain zoonotic bacterial diseases
0.674 0.325 0.000
A15-A19 Tuberculosis
0.674 0.325 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.674 0.326 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.673 0.327 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.673 0.327 0.000
T39.4 Antirheumatics, not elsewhere classified
0.673 0.327 0.000
T39.2 Pyrazolone derivatives
0.673 0.327 0.000
G95 Other diseases of spinal cord
0.672 0.328 0.000
A49 Bacterial infection of unspecified site
0.671 0.329 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.671 0.329 0.000
T91.1 Sequelae of fracture of spine
0.671 0.329 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.669 0.331 0.000
J46 Status asthmaticus
0.668 0.332 0.000
V10-V19 Pedal cyclist injured in transport accident
0.668 0.332 0.000
T79-T79 Certain early complications of trauma
0.668 0.332 0.000
E27 Other disorders of adrenal gland
0.667 0.333 0.000
G44 Other headache syndromes
0.666 0.334 0.000
Y59 Other and unspecified vaccines and biological substances
0.666 0.334 0.000
Y58 Bacterial vaccines
0.666 0.334 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.666 0.334 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.666 0.334 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.666 0.334 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.666 0.334 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.666 0.334 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.666 0.334 0.000
Y48 Anaesthetics and therapeutic gases
0.666 0.334 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.666 0.334 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.666 0.334 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.665 0.335 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.665 0.335 0.000
Y98 Lifestyle-related condition
0.665 0.335 0.000
Y97 Environmental-pollution-related condition
0.665 0.335 0.000
Y96 Work-related condition
0.665 0.335 0.000
Y89 Sequelae of other external causes
0.664 0.336 0.000
Y88 Sequelae of surgical and medical care as external cause
0.664 0.336 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.664 0.336 0.000
Q60-Q64 Congenital malformations of the urinary system
0.664 0.336 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.664 0.336 0.000
J04 Acute laryngitis and tracheitis
0.664 0.336 0.000
E10.9 Without complications
0.664 0.336 0.000
Y57.5 X-ray contrast media
0.664 0.336 0.000
E61 Deficiency of other nutrient elements
0.663 0.337 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.662 0.338 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.662 0.338 0.000
T93 Sequelae of injuries of lower limb
0.662 0.338 0.000
J00 Acute nasopharyngitis [common cold]
0.661 0.338 0.000
E15 Nondiabetic hypoglycaemic coma
0.661 0.339 0.000
J15.1 Pneumonia due to Pseudomonas
0.661 0.339 0.000
D53 Other nutritional anaemias
0.661 0.339 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.660 0.340 0.000
E06 Thyroiditis
0.660 0.340 0.000
T63 Toxic effect of contact with venomous animals
0.659 0.340 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.659 0.341 0.000
B15-B19 Viral hepatitis
0.659 0.341 0.000
S00.9 Superficial injury of head, part unspecified
0.658 0.342 0.000
H60-H62 Diseases of external ear
0.657 0.343 0.000
J69.0 Pneumonitis due to food and vomit
0.657 0.343 0.000
A00-A09 Intestinal infectious diseases
0.656 0.344 0.000
T98 Sequelae of other and unspecified effects of external causes
0.654 0.346 0.000
T95 Sequelae of burns, corrosions and frostbite
0.654 0.346 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.654 0.346 0.000
T92 Sequelae of injuries of upper limb
0.654 0.346 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.654 0.346 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.654 0.346 0.000
S00.7 Multiple superficial injuries of head
0.654 0.346 0.000
S00.5 Superficial injury of lip and oral cavity
0.654 0.346 0.000
S00.4 Superficial injury of ear
0.654 0.346 0.000
S00.3 Superficial injury of nose
0.654 0.346 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.654 0.346 0.000
L40-L45 Papulosquamous disorders
0.652 0.348 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.651 0.349 0.000
I26 Pulmonary embolism
0.650 0.350 0.000
Q80-Q89 Other congenital malformations
0.650 0.350 0.000
A41.9 Septicaemia, unspecified
0.647 0.353 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.647 0.353 0.000
E00 Congenital iodine-deficiency syndrome
0.647 0.353 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.647 0.353 0.000
N18.9 Chronic renal failure, unspecified
0.646 0.354 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.645 0.355 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.645 0.355 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.645 0.355 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.645 0.355 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.645 0.355 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.645 0.355 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.645 0.355 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.645 0.355 0.000
E28 Ovarian dysfunction
0.644 0.356 0.000
D50.9 Iron deficiency anaemia, unspecified
0.644 0.356 0.000
E11.5 With peripheral circulatory complications
0.643 0.357 0.000
G93 Other disorders of brain
0.642 0.358 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.642 0.358 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.642 0.358 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.642 0.358 0.000
D51.2 Transcobalamin II deficiency
0.642 0.358 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.642 0.358 0.000
S06.5 Traumatic subdural haemorrhage
0.642 0.358 0.000
H53-H54 Visual disturbances and blindness
0.642 0.358 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.639 0.361 0.000
S40 Superficial injury of shoulder and upper arm
0.639 0.361 0.000
Y85.0 Sequelae of motor-vehicle accident
0.638 0.362 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.638 0.362 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.638 0.362 0.000
E83.8 Other disorders of mineral metabolism
0.638 0.362 0.000
E83.2 Disorders of zinc metabolism
0.638 0.362 0.000
E83.0 Disorders of copper metabolism
0.638 0.362 0.000
S65.5 Injury of blood vessel(s) of other finger
0.637 0.363 0.000
S61.8 Open wound of other parts of wrist and hand
0.637 0.363 0.000
E87.4 Mixed disorder of acid-base balance
0.637 0.363 0.000
E87.3 Alkalosis
0.637 0.363 0.000
F60-F69 Disorders of adult personality and behaviour
0.636 0.363 0.000
E10.3 With ophthalmic complications
0.636 0.364 0.000
S62.6 Fracture of other finger
0.636 0.364 0.000
Y40.9 Systemic antibiotic, unspecified
0.635 0.365 0.000
G96 Other disorders of central nervous system
0.633 0.367 0.000
J01.9 Acute sinusitis, unspecified
0.633 0.367 0.000
Q00-Q07 Congenital malformations of the nervous system
0.633 0.367 0.000
T43.9 Psychotropic drug, unspecified
0.632 0.368 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.632 0.368 0.000
T43.6 Psychostimulants with abuse potential
0.632 0.368 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.632 0.368 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.632 0.368 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.632 0.368 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.630 0.370 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.628 0.372 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.627 0.373 0.000
B33 Other viral diseases, not elsewhere classified
0.626 0.374 0.000
B30 Viral conjunctivitis
0.626 0.374 0.000
B27 Infectious mononucleosis
0.626 0.374 0.000
B26 Mumps
0.626 0.374 0.000
B25 Cytomegaloviral disease
0.626 0.374 0.000
T17 Foreign body in respiratory tract
0.625 0.374 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.626 0.374 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.625 0.375 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.625 0.375 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.625 0.375 0.000
H55-H59 Other disorders of eye and adnexa
0.624 0.376 0.000
J43.8 Other emphysema
0.624 0.376 0.000
J43.1 Panlobular emphysema
0.624 0.376 0.000
J43.0 MacLeod's syndrome
0.624 0.376 0.000
E53 Deficiency of other B group vitamins
0.623 0.377 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.622 0.378 0.000
F70-F79 Mental retardation
0.622 0.378 0.000
J02 Acute pharyngitis
0.622 0.378 0.000
I78 Diseases of capillaries
0.622 0.378 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.622 0.378 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.622 0.378 0.000
E16.4 Abnormal secretion of gastrin
0.622 0.378 0.000
E16.3 Increased secretion of glucagon
0.622 0.378 0.000
E16.1 Other hypoglycaemia
0.622 0.378 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.622 0.378 0.000
E10.5 With peripheral circulatory complications
0.621 0.379 0.000
A48 Other bacterial diseases, not elsewhere classified
0.620 0.380 0.000
A44 Bartonellosis
0.620 0.380 0.000
A43 Nocardiosis
0.620 0.380 0.000
A42 Actinomycosis
0.620 0.380 0.000
A40 Streptococcal septicaemia
0.620 0.380 0.000
A39 Meningococcal infection
0.620 0.380 0.000
A37 Whooping cough
0.620 0.380 0.000
A36 Diphtheria
0.620 0.380 0.000
A32 Listeriosis
0.620 0.380 0.000
A31 Infection due to other mycobacteria
0.620 0.380 0.000
A30 Leprosy [Hansen's disease]
0.620 0.380 0.000
A46 Erysipelas
0.620 0.380 0.000
A38 Scarlet fever
0.620 0.380 0.000
A35 Other tetanus
0.620 0.380 0.000
A34 Obstetrical tetanus
0.620 0.380 0.000
A33 Tetanus neonatorum
0.620 0.380 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.619 0.381 0.000
F80-F89 Disorders of psychological development
0.619 0.381 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.618 0.382 0.000
E14 Unspecified diabetes mellitus
0.617 0.382 0.000
G54 Nerve root and plexus disorders
0.617 0.383 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.617 0.383 0.000
G52 Disorders of other cranial nerves
0.617 0.383 0.000
T19 Foreign body in genito-urinary tract
0.616 0.384 0.000
T15 Foreign body on external eye
0.616 0.384 0.000
T16 Foreign body in ear
0.616 0.384 0.000
L20-L30 Dermatitis and eczema
0.616 0.384 0.000
N18.2 Chronic kidney disease, stage 2
0.616 0.384 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.616 0.384 0.000
G25 Other extrapyramidal and movement disorders
0.615 0.385 0.000
I95.1 Orthostatic hypotension
0.615 0.385 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.613 0.387 0.000
E34 Other endocrine disorders
0.613 0.387 0.000
E32 Diseases of thymus
0.613 0.387 0.000
E31 Polyglandular dysfunction
0.613 0.387 0.000
E30 Disorders of puberty, not elsewhere classified
0.613 0.387 0.000
E26 Hyperaldosteronism
0.613 0.387 0.000
E25 Adrenogenital disorders
0.613 0.387 0.000
E24 Cushing's syndrome
0.613 0.387 0.000
E20 Hypoparathyroidism
0.613 0.387 0.000
J32 Chronic sinusitis
0.613 0.387 0.000
S20-S29 Injuries to the thorax
0.613 0.387 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.612 0.387 0.000
M47 Spondylosis
0.613 0.387 0.000
Y57.8 Other drugs and medicaments
0.612 0.388 0.000
Y57.7 Vitamins, not elsewhere classified
0.612 0.388 0.000
Y57.6 Other diagnostic agents
0.612 0.388 0.000
Y57.4 Pharmaceutical excipients
0.612 0.388 0.000
Y57.3 Alcohol deterrents
0.612 0.388 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.612 0.388 0.000
Y57.1 Lipotropic drugs
0.612 0.388 0.000
Y57.0 Appetite depressants [anorectics]
0.612 0.388 0.000
N25-N29 Other disorders of kidney and ureter
0.612 0.388 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.611 0.389 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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