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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13180087
log Bayes Factor = 2.35122
Chromosome 5   position 45,265,768  (GRCh37) Explore rs13180087 on Ensembl!
Variant rs13180087 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
T36-T50 Poisoning by drugs, medicaments and biological substances
0.994 0.006 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.993 0.007 0.000
# Top node
0.992 0.008 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.991 0.009 0.000
Chapter V Mental and behavioural disorders
0.988 0.012 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.984 0.016 0.000
F20 Schizophrenia
0.982 0.018 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.975 0.025 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.970 0.030 0.000
F20.9 Schizophrenia, unspecified
0.966 0.034 0.000
D80-D89 Certain disorders involving the immune mechanism
0.960 0.040 0.000
F20.0 Paranoid schizophrenia
0.955 0.045 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.954 0.046 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.953 0.047 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.948 0.052 0.000
Chapter VIII Diseases of the ear and mastoid process
0.946 0.054 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.946 0.054 0.000
E10-E14 Diabetes mellitus
0.939 0.061 0.000
E50-E64 Other nutritional deficiencies
0.936 0.064 0.000
D55-D59 Haemolytic anaemias
0.935 0.065 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.931 0.069 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.930 0.070 0.000
E16 Other disorders of pancreatic internal secretion
0.925 0.075 0.000
E16.2 Hypoglycaemia, unspecified
0.911 0.089 0.000
H80-H83 Diseases of inner ear
0.905 0.095 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.901 0.099 0.000
Chapter XX External causes of morbidity and mortality
0.891 0.109 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.888 0.112 0.000
E53 Deficiency of other B group vitamins
0.888 0.112 0.000
D86 Sarcoidosis
0.887 0.113 0.000
H81 Disorders of vestibular function
0.880 0.120 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.880 0.120 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.877 0.123 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.874 0.126 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.871 0.129 0.000
E11 Non-insulin-dependent diabetes mellitus
0.868 0.132 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.868 0.132 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.865 0.135 0.000
Q60-Q64 Congenital malformations of the urinary system
0.865 0.135 0.000
E10 Insulin-dependent diabetes mellitus
0.864 0.136 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.864 0.136 0.000
T45.5 Anticoagulants
0.859 0.141 0.000
E53.8 Deficiency of other specified B group vitamins
0.859 0.141 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.858 0.142 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.857 0.143 0.000
Chapter I Certain infectious and parasitic diseases
0.854 0.146 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.851 0.149 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.850 0.150 0.000
D58 Other hereditary haemolytic anaemias
0.848 0.152 0.000
S20-S29 Injuries to the thorax
0.847 0.153 0.000
T36 Poisoning by systemic antibiotics
0.846 0.154 0.000
T66-T78 Other and unspecified effects of external causes
0.845 0.155 0.000
X60-X84 Intentional self-harm
0.845 0.155 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.840 0.160 0.000
N18.9 Chronic renal failure, unspecified
0.839 0.161 0.000
N18 Chronic renal failure
0.836 0.164 0.000
D80 Immunodeficiency with predominantly antibody defects
0.836 0.164 0.000
S90-S99 Injuries to the ankle and foot
0.834 0.166 0.000
H81.1 Benign paroxysmal vertigo
0.829 0.171 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.827 0.173 0.000
N17-N19 Renal failure
0.827 0.173 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.825 0.175 0.000
H65-H75 Diseases of middle ear and mastoid
0.821 0.179 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.820 0.180 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.818 0.182 0.000
D60-D64 Aplastic and other anaemias
0.818 0.182 0.000
T39.1 4-Aminophenol derivatives
0.816 0.184 0.000
D59 Acquired haemolytic anaemia
0.815 0.185 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.814 0.186 0.000
Chapter XXII Codes for special purposes
0.813 0.187 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.813 0.187 0.000
D73 Diseases of spleen
0.812 0.188 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.809 0.191 0.000
H81.2 Vestibular neuronitis
0.806 0.194 0.000
A30-A49 Other bacterial diseases
0.802 0.198 0.000
Chapter XIV Diseases of the genitourinary system
0.798 0.202 0.000
F25 Schizoaffective disorders
0.795 0.204 0.000
N17 Acute renal failure
0.792 0.208 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.792 0.208 0.000
S00-S09 Injuries to the head
0.790 0.210 0.000
D86.0 Sarcoidosis of lung
0.785 0.215 0.000
T43.2 Other and unspecified antidepressants
0.782 0.218 0.000
E11.4 With neurological complications
0.781 0.219 0.000
E11.6 With other specified complications
0.780 0.220 0.000
A41 Other septicaemia
0.778 0.222 0.000
T46.1 Calcium-channel blockers
0.776 0.224 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.776 0.224 0.000
N17.9 Acute renal failure, unspecified
0.775 0.225 0.000
T45.0 Antiallergic and antiemetic drugs
0.775 0.225 0.000
D86.9 Sarcoidosis, unspecified
0.771 0.229 0.000
S21 Open wound of thorax
0.770 0.230 0.000
F60-F69 Disorders of adult personality and behaviour
0.764 0.236 0.000
F80-F89 Disorders of psychological development
0.760 0.240 0.000
Q35-Q37 Cleft lip and cleft palate
0.760 0.240 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.759 0.241 0.000
N18.4 Chronic kidney disease, stage 4
0.758 0.242 0.000
E58 Dietary calcium deficiency
0.754 0.246 0.000
D58.0 Hereditary spherocytosis
0.754 0.246 0.000
Y00-Y09 Assault
0.752 0.248 0.000
D68 Other coagulation defects
0.752 0.248 0.000
F70-F79 Mental retardation
0.750 0.250 0.000
W50-W64 Exposure to animate mechanical forces
0.749 0.251 0.000
W20-W49 Exposure to inanimate mechanical forces
0.747 0.253 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.746 0.254 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.744 0.256 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.744 0.256 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.743 0.257 0.000
T36.0 Penicillins
0.740 0.260 0.000
E55 Vitamin D deficiency
0.739 0.261 0.000
E10.1 With ketoacidosis
0.739 0.261 0.000
T00-T07 Injuries involving multiple body regions
0.738 0.261 0.000
D73.5 Infarction of spleen
0.738 0.262 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.737 0.263 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.735 0.265 0.000
T40.4 Other synthetic narcotics
0.735 0.265 0.000
E10.4 With neurological complications
0.733 0.267 0.000
F12.2 Dependence syndrome
0.732 0.268 0.000
A41.9 Septicaemia, unspecified
0.732 0.268 0.000
E10.9 Without complications
0.729 0.271 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.727 0.273 0.000
S05 Injury of eye and orbit
0.727 0.273 0.000
E10.0 With coma
0.727 0.273 0.000
Q66 Congenital deformities of feet
0.724 0.276 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.722 0.278 0.000
A80-A89 Viral infections of the central nervous system
0.722 0.278 0.000
F17.2 Dependence syndrome
0.721 0.279 0.000
B50-B64 Protozoal diseases
0.719 0.281 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.717 0.283 0.000
D83 Common variable immunodeficiency
0.715 0.285 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.714 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.713 0.287 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.712 0.287 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.712 0.287 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.712 0.287 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.712 0.287 0.000
E51 Thiamine deficiency
0.712 0.288 0.000
T33-T35 Frostbite
0.712 0.288 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.288 0.000
F17.1 Harmful use
0.712 0.288 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.711 0.289 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.710 0.289 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.709 0.291 0.000
N18.5 Chronic kidney disease, stage 5
0.707 0.293 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.707 0.293 0.000
D84 Other immunodeficiencies
0.706 0.294 0.000
F28 Other nonorganic psychotic disorders
0.705 0.294 0.000
F24 Induced delusional disorder
0.705 0.294 0.000
F21 Schizotypal disorder
0.705 0.294 0.000
F12.0 Acute intoxication
0.705 0.295 0.000
T40.2 Other opioids
0.705 0.295 0.000
F20.8 Other schizophrenia
0.704 0.296 0.000
F20.6 Simple schizophrenia
0.704 0.296 0.000
F20.5 Residual schizophrenia
0.704 0.296 0.000
F20.4 Postschizophrenic depression
0.704 0.296 0.000
F20.3 Undifferentiated schizophrenia
0.704 0.296 0.000
F20.2 Catatonic schizophrenia
0.704 0.296 0.000
F20.1 Hebephrenic schizophrenia
0.704 0.296 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.702 0.298 0.000
T43.6 Psychostimulants with abuse potential
0.701 0.299 0.000
S21.2 Open wound of back wall of thorax
0.699 0.301 0.000
E11.1 With ketoacidosis
0.699 0.301 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.696 0.304 0.000
Q12 Congenital lens malformations
0.695 0.305 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.695 0.305 0.000
H74 Other disorders of middle ear and mastoid
0.695 0.305 0.000
Q80-Q89 Other congenital malformations
0.695 0.305 0.000
D62 Acute posthaemorrhagic anaemia
0.693 0.307 0.000
F15.1 Harmful use
0.693 0.307 0.000
V01-V09 Pedestrian injured in transport accident
0.691 0.309 0.000
S20 Superficial injury of thorax
0.691 0.309 0.000
D58.9 Hereditary haemolytic anaemia, unspecified
0.689 0.310 0.000
D86.1 Sarcoidosis of lymph nodes
0.689 0.311 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.689 0.311 0.000
N10-N16 Renal tubulo-interstitial diseases
0.689 0.311 0.000
D82 Immunodeficiency associated with other major defects
0.688 0.312 0.000
D81 Combined immunodeficiencies
0.688 0.312 0.000
D73.0 Hyposplenism
0.688 0.312 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.688 0.312 0.000
S29 Other and unspecified injuries of thorax
0.688 0.312 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.688 0.312 0.000
H80 Otosclerosis
0.687 0.313 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.687 0.313 0.000
Y10-Y34 Event of undetermined intent
0.686 0.314 0.000
T71 Asphyxiation
0.686 0.314 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.686 0.314 0.000
T78 Adverse effects, not elsewhere classified
0.686 0.314 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.685 0.315 0.000
F22 Persistent delusional disorders
0.684 0.316 0.000
N18.3 Chronic kidney disease, stage 3
0.684 0.316 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.684 0.316 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.684 0.316 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.683 0.317 0.000
T83.2 Mechanical complication of graft of urinary organ
0.683 0.317 0.000
T42.4 Benzodiazepines
0.683 0.317 0.000
E10.6 With other specified complications
0.682 0.318 0.000
T43.9 Psychotropic drug, unspecified
0.679 0.320 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.679 0.320 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.679 0.320 0.000
E15 Nondiabetic hypoglycaemic coma
0.678 0.322 0.000
V98-V99 Other and unspecified transport accidents
0.678 0.322 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.677 0.323 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.677 0.323 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.675 0.324 0.000
B99-B99 Other infectious diseases
0.675 0.325 0.000
Q40 Other congenital malformations of upper alimentary tract
0.675 0.325 0.000
Q63 Other congenital malformations of kidney
0.674 0.326 0.000
F50 Eating disorders
0.674 0.326 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.674 0.326 0.000
H70 Mastoiditis and related conditions
0.673 0.327 0.000
E12 Malnutrition-related diabetes mellitus
0.673 0.327 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.673 0.327 0.000
T79-T79 Certain early complications of trauma
0.672 0.327 0.000
H90-H95 Other disorders of ear
0.671 0.329 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.671 0.329 0.000
E63 Other nutritional deficiencies
0.671 0.329 0.000
E56 Other vitamin deficiencies
0.671 0.329 0.000
E50 Vitamin A deficiency
0.671 0.329 0.000
E60 Dietary zinc deficiency
0.671 0.329 0.000
E59 Dietary selenium deficiency
0.671 0.329 0.000
E54 Ascorbic acid deficiency
0.671 0.329 0.000
E52 Niacin deficiency [pellagra]
0.671 0.329 0.000
D57 Sickle-cell disorders
0.671 0.329 0.000
D56 Thalassaemia
0.671 0.329 0.000
D55 Anaemia due to enzyme disorders
0.671 0.329 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.670 0.330 0.000
S99 Other and unspecified injuries of ankle and foot
0.669 0.331 0.000
Q61 Cystic kidney disease
0.669 0.331 0.000
H73 Other disorders of tympanic membrane
0.669 0.331 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.668 0.331 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.668 0.332 0.000
T45.8 Other primarily systemic and haematological agents
0.668 0.332 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.668 0.332 0.000
T45.6 Fibrinolysis-affecting drugs
0.668 0.332 0.000
T45.4 Iron and its compounds
0.668 0.332 0.000
T45.3 Enzymes, not elsewhere classified
0.668 0.332 0.000
T45.2 Vitamins, not elsewhere classified
0.668 0.332 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.667 0.332 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.667 0.333 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.666 0.333 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.666 0.333 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.666 0.333 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.666 0.333 0.000
N00-N08 Glomerular diseases
0.666 0.334 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.666 0.334 0.000
S09 Other and unspecified injuries of head
0.664 0.336 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.664 0.336 0.000
H69 Other disorders of Eustachian tube
0.664 0.336 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.663 0.336 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.663 0.336 0.000
E16.4 Abnormal secretion of gastrin
0.663 0.336 0.000
E16.3 Increased secretion of glucagon
0.663 0.336 0.000
E16.1 Other hypoglycaemia
0.663 0.336 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.663 0.337 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.661 0.339 0.000
F12.1 Harmful use
0.661 0.339 0.000
W75-W84 Other accidental threats to breathing
0.661 0.339 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.660 0.340 0.000
E11.0 With coma
0.660 0.340 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.659 0.341 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.658 0.342 0.000
Y04 Assault by bodily force
0.658 0.342 0.000
D72 Other disorders of white blood cells
0.658 0.342 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.657 0.343 0.000
F99-F99 Unspecified mental disorder
0.657 0.343 0.000
E13 Other specified diabetes mellitus
0.657 0.343 0.000
T75 Effects of other external causes
0.657 0.343 0.000
F11 Mental and behavioural disorders due to use of opioids
0.656 0.344 0.000
D59.1 Other autoimmune haemolytic anaemias
0.656 0.344 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.654 0.346 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.654 0.346 0.000
T70 Effects of air pressure and water pressure
0.653 0.347 0.000
Q39 Congenital malformations of oesophagus
0.652 0.348 0.000
E11.5 With peripheral circulatory complications
0.651 0.349 0.000
F51 Nonorganic sleep disorders
0.651 0.349 0.000
Q00-Q07 Congenital malformations of the nervous system
0.650 0.349 0.000
Q64 Other congenital malformations of urinary system
0.650 0.350 0.000
T42.1 Iminostilbenes
0.650 0.350 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.649 0.351 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.649 0.351 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.648 0.352 0.000
Q50-Q56 Congenital malformations of genital organs
0.648 0.352 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.647 0.353 0.000
W21 Striking against or struck by sports equipment
0.647 0.353 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.646 0.354 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.646 0.354 0.000
T46.7 Peripheral vasodilators
0.646 0.354 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.646 0.354 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.646 0.354 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.646 0.354 0.000
H65 Nonsuppurative otitis media
0.646 0.354 0.000
V10-V19 Pedal cyclist injured in transport accident
0.645 0.355 0.000
X10-X19 Contact with heat and hot substances
0.644 0.355 0.000
Q17 Other congenital malformations of ear
0.644 0.356 0.000
A00-A09 Intestinal infectious diseases
0.643 0.357 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.641 0.359 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.640 0.360 0.000
T87 Complications peculiar to reattachment and amputation
0.640 0.360 0.000
T42.0 Hydantoin derivatives
0.639 0.360 0.000
A15-A19 Tuberculosis
0.639 0.360 0.000
Y35-Y36 Legal intervention and operations of war
0.639 0.361 0.000
X85-X99 Assault
0.639 0.361 0.000
X30-X39 Exposure to forces of nature
0.639 0.361 0.000
X00-X09 Exposure to smoke, fire and flames
0.639 0.361 0.000
W65-W74 Accidental drowning and submersion
0.639 0.361 0.000
V95-V97 Air and space transport accidents
0.639 0.361 0.000
V90-V94 Water transport accidents
0.639 0.361 0.000
V70-V79 Bus occupant injured in transport accident
0.639 0.361 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.639 0.361 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.639 0.361 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.639 0.361 0.000
T86 Failure and rejection of transplanted organs and tissues
0.638 0.362 0.000
T13 Other injuries of lower limb, level unspecified
0.638 0.362 0.000
E53.1 Pyridoxine deficiency
0.637 0.363 0.000
E53.0 Riboflavin deficiency
0.637 0.363 0.000
D86.3 Sarcoidosis of skin
0.636 0.364 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.636 0.364 0.000
H81.9 Disorder of vestibular function, unspecified
0.635 0.365 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.635 0.365 0.000
Q43 Other congenital malformations of intestine
0.634 0.366 0.000
X62.9 Unspecified place
0.634 0.366 0.000
Q44.6 Cystic disease of liver
0.634 0.366 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.634 0.366 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.634 0.366 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.633 0.367 0.000
A87 Viral meningitis
0.633 0.367 0.000
N18.0 End-stage renal disease
0.632 0.368 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.632 0.368 0.000
H81.8 Other disorders of vestibular function
0.631 0.369 0.000
H81.4 Vertigo of central origin
0.631 0.369 0.000
S91 Open wound of ankle and foot
0.631 0.369 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.631 0.369 0.000
T39.4 Antirheumatics, not elsewhere classified
0.631 0.369 0.000
T39.2 Pyrazolone derivatives
0.631 0.369 0.000
H81.3 Other peripheral vertigo
0.629 0.371 0.000
E40-E46 Malnutrition
0.629 0.371 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.626 0.374 0.000
D68.8 Other specified coagulation defects
0.625 0.375 0.000
D67 Hereditary factor IX deficiency
0.625 0.375 0.000
W55 Bitten or struck by other mammals
0.624 0.376 0.000
D68.6 Other Thrombophilia
0.623 0.376 0.000
Y57 Other and unspecified drugs and medicaments
0.623 0.377 0.000
E11.7 With multiple complications
0.623 0.377 0.000
F25.0 Schizoaffective disorder, manic type
0.622 0.377 0.000
F84 Pervasive developmental disorders
0.622 0.378 0.000
V40-V49 Car occupant injured in transport accident
0.622 0.378 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.622 0.378 0.000
D74 Methaemoglobinaemia
0.622 0.378 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.622 0.378 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.622 0.378 0.000
T31 Burns classified according to extent of body surface involved
0.620 0.380 0.000
E10.7 With multiple complications
0.620 0.380 0.000
F25.9 Schizoaffective disorder, unspecified
0.620 0.380 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.619 0.380 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.619 0.380 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.619 0.380 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.619 0.380 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.619 0.380 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.619 0.380 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.619 0.380 0.000
T44.0 Anticholinesterase agents
0.619 0.380 0.000
F23 Acute and transient psychotic disorders
0.619 0.380 0.000
A65-A69 Other spirochaetal diseases
0.619 0.380 0.000
S06 Intracranial injury
0.619 0.381 0.000
T14 Injury of unspecified body region
0.619 0.381 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.619 0.381 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.617 0.383 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.615 0.385 0.000
T40.8 Lysergide [LSD]
0.615 0.385 0.000
T40.7 Cannabis (derivatives)
0.615 0.385 0.000
T40.5 Cocaine
0.615 0.385 0.000
T40.3 Methadone
0.615 0.385 0.000
T40.1 Heroin
0.615 0.385 0.000
T40.0 Opium
0.615 0.385 0.000
Q45 Other congenital malformations of digestive system
0.615 0.385 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.615 0.385 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.615 0.385 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.615 0.385 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.613 0.387 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.612 0.388 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.612 0.388 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.612 0.388 0.000
A75-A79 Rickettsioses
0.612 0.388 0.000
A70-A74 Other diseases caused by chlamydiae
0.612 0.388 0.000
A20-A28 Certain zoonotic bacterial diseases
0.612 0.388 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.612 0.388 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.611 0.389 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.611 0.389 0.000
W20 Struck by thrown, projected or falling object
0.611 0.389 0.000
N03 Chronic nephritic syndrome
0.610 0.390 0.000
Q78 Other osteochondrodysplasias
0.610 0.390 0.000
D69 Purpura and other haemorrhagic conditions
0.610 0.390 0.000
Q12.0 Congenital cataract
0.610 0.390 0.000
E14 Unspecified diabetes mellitus
0.610 0.390 0.000
F12.9 Unspecified mental and behavioural disorder
0.610 0.390 0.000
F12.8 Other mental and behavioural disorders
0.610 0.390 0.000
F12.7 Residual and late-onset psychotic disorder
0.610 0.390 0.000
F12.6 Amnesic syndrome
0.610 0.390 0.000
F12.5 Psychotic disorder
0.610 0.390 0.000
F12.4 Withdrawal state with delirium
0.610 0.390 0.000
F12.3 Withdrawal state
0.610 0.390 0.000
Q35 Cleft palate
0.609 0.391 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.609 0.391 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.609 0.391 0.000
F55 Abuse of non-dependence-producing substances
0.609 0.391 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.609 0.391 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.608 0.392 0.000
D58.2 Other haemoglobinopathies
0.608 0.392 0.000
D58.1 Hereditary elliptocytosis
0.608 0.392 0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.608 0.392 0.000
E10.5 With peripheral circulatory complications
0.607 0.392 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.607 0.393 0.000
S26 Injury of heart
0.607 0.393 0.000
S25 Injury of blood vessels of thorax
0.607 0.393 0.000
S24 Injury of nerves and spinal cord at thorax level
0.607 0.393 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.607 0.393 0.000
S05.9 Injury of eye and orbit, part unspecified
0.607 0.393 0.000
T21 Burn and corrosion of trunk
0.607 0.393 0.000
T36.9 Systemic antibiotic, unspecified
0.606 0.393 0.000
T36.8 Other systemic antibiotics
0.606 0.393 0.000
T36.7 Antifungal antibiotics, systemically used
0.606 0.393 0.000
T36.6 Rifamycins
0.606 0.393 0.000
T36.5 Aminoglycosides
0.606 0.393 0.000
T36.4 Tetracyclines
0.606 0.393 0.000
T36.3 Macrolides
0.606 0.393 0.000
T36.2 Chloramphenicol group
0.606 0.393 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.606 0.393 0.000
E65-E68 Obesity and other hyperalimentation
0.606 0.394 0.000
T74 Maltreatment syndromes
0.606 0.394 0.000
T73 Effects of other deprivation
0.606 0.394 0.000
T69 Other effects of reduced temperature
0.606 0.394 0.000
T67 Effects of heat and light
0.606 0.394 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.606 0.394 0.000
X84 Intentional self-harm by unspecified means
0.606 0.394 0.000
X83 Intentional self-harm by other specified means
0.606 0.394 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.606 0.394 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.606 0.394 0.000
X80 Intentional self-harm by jumping from a high place
0.606 0.394 0.000
X79 Intentional self-harm by blunt object
0.606 0.394 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.606 0.394 0.000
X76 Intentional self-harm by smoke, fire and flames
0.606 0.394 0.000
X75 Intentional self-harm by explosive material
0.606 0.394 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.606 0.394 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.606 0.394 0.000
X72 Intentional self-harm by handgun discharge
0.606 0.394 0.000
X71 Intentional self-harm by drowning and submersion
0.606 0.394 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.606 0.394 0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.606 0.394 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.606 0.394 0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.606 0.394 0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.606 0.394 0.000
Q65 Congenital deformities of hip
0.605 0.395 0.000
H65.4 Other chronic nonsuppurative otitis media
0.605 0.395 0.000
Q66.8 Other congenital deformities of feet
0.604 0.396 0.000
F17.9 Unspecified mental and behavioural disorder
0.602 0.398 0.000
F17.8 Other mental and behavioural disorders
0.602 0.398 0.000
F17.7 Residual and late-onset psychotic disorder
0.602 0.398 0.000
F17.6 Amnesic syndrome
0.602 0.398 0.000
F17.5 Psychotic disorder
0.602 0.398 0.000
F17.4 Withdrawal state with delirium
0.602 0.398 0.000
F17.3 Withdrawal state
0.602 0.398 0.000
F17.0 Acute intoxication
0.602 0.398 0.000
D68.9 Coagulation defect, unspecified
0.602 0.398 0.000
B59 Pneumocystosis
0.602 0.398 0.000
S21.1 Open wound of front wall of thorax
0.601 0.398 0.000
A49 Bacterial infection of unspecified site
0.601 0.399 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.601 0.399 0.000
Q66.3 Other congenital varus deformities of feet
0.600 0.400 0.000
N18.1 Chronic kidney disease, stage 1
0.600 0.400 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.599 0.400 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.599 0.400 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.599 0.400 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.599 0.400 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.599 0.400 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.599 0.400 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.599 0.400 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.599 0.400 0.000
S90 Superficial injury of ankle and foot
0.599 0.401 0.000
T09 Other injuries of spine and trunk, level unspecified
0.599 0.401 0.000
S98 Traumatic amputation of ankle and foot
0.598 0.402 0.000
S97 Crushing injury of ankle and foot
0.598 0.402 0.000
S95 Injury of blood vessels at ankle and foot level
0.598 0.402 0.000
S94 Injury of nerves at ankle and foot level
0.598 0.402 0.000
E55.9 Vitamin D deficiency, unspecified
0.597 0.403 0.000
T66 Unspecified effects of radiation
0.596 0.404 0.000
E53.9 Vitamin B deficiency, unspecified
0.595 0.405 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.592 0.408 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.592 0.408 0.000
S70-S79 Injuries to the hip and thigh
0.592 0.408 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.591 0.408 0.000
Q75 Other congenital malformations of skull and face bones
0.591 0.408 0.000
Q74 Other congenital malformations of limb(s)
0.591 0.408 0.000
Q73 Reduction defects of unspecified limb
0.591 0.408 0.000
Q72 Reduction defects of lower limb
0.591 0.408 0.000
Q71 Reduction defects of upper limb
0.591 0.408 0.000
Q70 Syndactyly
0.591 0.408 0.000
Q69 Polydactyly
0.591 0.408 0.000
Q68 Other congenital musculoskeletal deformities
0.591 0.408 0.000
Y04.8 Other specified place
0.590 0.410 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.589 0.411 0.000
H68 Eustachian salpingitis and obstruction
0.589 0.411 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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