TreeWAS – Variant ID: rs13214703

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
G35 Multiple sclerosis	1.000	0.000	0.000
Chapter VI Diseases of the nervous system	1.000	0.000	0.000
G35-G37 Demyelinating diseases of the central nervous system	1.000	0.000	0.000
# Top node	0.997	0.003	0.000
Chapter XX External causes of morbidity and mortality	0.995	0.005	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.983	0.017	0.000
G20-G26 Extrapyramidal and movement disorders	0.982	0.018	0.000
W00-W19 Falls	0.980	0.020	0.000
Chapter V Mental and behavioural disorders	0.978	0.022	0.000
K70-K77 Diseases of liver	0.971	0.029	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.970	0.030	0.000
L03.1 Cellulitis of other parts of limb	0.968	0.032	0.000
K70 Alcoholic liver disease	0.968	0.032	0.000
L03 Cellulitis	0.966	0.034	0.000
K76 Other diseases of liver	0.960	0.040	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.955	0.045	0.000
Chapter XI Diseases of the digestive system	0.950	0.050	0.000
G30-G32 Other degenerative diseases of the nervous system	0.946	0.054	0.000
K74 Fibrosis and cirrhosis of liver	0.945	0.055	0.000
V40-V49 Car occupant injured in transport accident	0.944	0.056	0.000
K76.6 Portal hypertension	0.942	0.058	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.932	0.068	0.000
G40-G47 Episodic and paroxysmal disorders	0.925	0.075	0.000
E83 Disorders of mineral metabolism	0.925	0.075	0.000
K70.3 Alcoholic cirrhosis of liver	0.922	0.078	0.000
G25 Other extrapyramidal and movement disorders	0.919	0.081	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.918	0.082	0.000
E70-E90 Metabolic disorders	0.917	0.083	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.917	0.083	0.000
L20-L30 Dermatitis and eczema	0.917	0.083	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.911	0.089	0.000
W19 Unspecified fall	0.905	0.095	0.000
Y40 Systemic antibiotics	0.905	0.095	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.895	0.105	0.000
S60-S69 Injuries to the wrist and hand	0.894	0.106	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.891	0.109	0.000
K74.0 Hepatic fibrosis	0.889	0.111	0.000
F60-F69 Disorders of adult personality and behaviour	0.886	0.114	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.885	0.115	0.000
V49 Car occupant injured in other and unspecified transport accidents	0.884	0.116	0.000
I83 Varicose veins of lower extremities	0.884	0.116	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.883	0.117	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.883	0.117	0.000
Chapter IX Diseases of the circulatory system	0.878	0.122	0.000
G40 Epilepsy	0.876	0.124	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.876	0.124	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.876	0.124	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.874	0.126	0.000
V10-V19 Pedal cyclist injured in transport accident	0.868	0.132	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.865	0.135	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.865	0.135	0.000
K70.0 Alcoholic fatty liver	0.865	0.135	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.864	0.136	0.000
V80-V89 Other land transport accidents	0.864	0.136	0.000
F10.0 Acute intoxication	0.862	0.138	0.000
W19.4 Street and highway	0.861	0.139	0.000
F10.2 Dependence syndrome	0.860	0.140	0.000
G24 Dystonia	0.859	0.141	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.857	0.143	0.000
T66-T78 Other and unspecified effects of external causes	0.857	0.143	0.000
W18 Other fall on same level	0.852	0.148	0.000
G20 Parkinson's disease	0.850	0.150	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.847	0.153	0.000
K70.4 Alcoholic hepatic failure	0.846	0.154	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.845	0.155	0.000
K74.6 Other and unspecified cirrhosis of liver	0.839	0.161	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.837	0.163	0.000
W17 Other fall from one level to another	0.831	0.169	0.000
G30 Alzheimer's disease	0.830	0.170	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.828	0.172	0.000
Chapter XXII Codes for special purposes	0.827	0.173	0.000
Y40.0 Penicillins	0.827	0.173	0.000
G47 Sleep disorders	0.807	0.193	0.000
Q80-Q89 Other congenital malformations	0.806	0.194	0.000
T93 Sequelae of injuries of lower limb	0.804	0.196	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.803	0.197	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.803	0.197	0.000
G90-G99 Other disorders of the nervous system	0.802	0.198	0.000
S00-S09 Injuries to the head	0.801	0.199	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.800	0.200	0.000
K40-K46 Hernia	0.799	0.201	0.000
Y40.9 Systemic antibiotic, unspecified	0.798	0.202	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.796	0.204	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.795	0.205	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.794	0.206	0.000
L30 Other dermatitis	0.792	0.208	0.000
K40 Inguinal hernia	0.792	0.208	0.000
E89.0 Postprocedural hypothyroidism	0.790	0.210	0.000
G37 Other demyelinating diseases of central nervous system	0.789	0.211	0.000
F99-F99 Unspecified mental disorder	0.788	0.212	0.000
I26 Pulmonary embolism	0.785	0.215	0.000
G47.9 Sleep disorder, unspecified	0.784	0.216	0.000
E89.2 Postprocedural hypoparathyroidism	0.783	0.216	0.000
T78 Adverse effects, not elsewhere classified	0.779	0.221	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.778	0.222	0.000
K50-K52 Noninfective enteritis and colitis	0.777	0.223	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.776	0.223	0.000
F60 Specific personality disorders	0.774	0.226	0.000
T91 Sequelae of injuries of neck and trunk	0.773	0.227	0.000
G44 Other headache syndromes	0.772	0.228	0.000
W19.2 School, other institution and public administrative area	0.771	0.229	0.000
S10-S19 Injuries to the neck	0.768	0.232	0.000
W06 Fall involving bed	0.767	0.232	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.765	0.235	0.000
V95-V97 Air and space transport accidents	0.765	0.235	0.000
X50-X57 Overexertion, travel and privation	0.764	0.236	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.763	0.237	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.763	0.237	0.000
K51 Ulcerative colitis	0.762	0.238	0.000
G31.2 Degeneration of nervous system due to alcohol	0.762	0.238	0.000
L28 Lichen simplex chronicus and prurigo	0.761	0.239	0.000
L50-L54 Urticaria and erythema	0.761	0.239	0.000
Y45.0 Opioids and related analgesics	0.761	0.239	0.000
V70-V79 Bus occupant injured in transport accident	0.760	0.240	0.000
Y44 Agents primarily affecting blood constituents	0.756	0.244	0.000
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.755	0.245	0.000
F10.5 Psychotic disorder	0.754	0.246	0.000
Q23 Congenital malformations of aortic and mitral valves	0.753	0.247	0.000
L03.2 Cellulitis of face	0.752	0.248	0.000
V48 Car occupant injured in noncollision transport accident	0.751	0.249	0.000
F70-F79 Mental retardation	0.750	0.250	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.750	0.250	0.000
W50-W64 Exposure to animate mechanical forces	0.749	0.251	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.748	0.252	0.000
X00-X09 Exposure to smoke, fire and flames	0.747	0.253	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.747	0.253	0.000
F80-F89 Disorders of psychological development	0.746	0.254	0.000
K76.7 Hepatorenal syndrome	0.746	0.254	0.000
S64 Injury of nerves at wrist and hand level	0.745	0.255	0.000
I87 Other disorders of veins	0.744	0.256	0.000
T90 Sequelae of injuries of head	0.742	0.258	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.741	0.259	0.000
Y00-Y09 Assault	0.740	0.260	0.000
K70.1 Alcoholic hepatitis	0.740	0.260	0.000
L20 Atopic dermatitis	0.740	0.260	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.739	0.261	0.000
S00 Superficial injury of head	0.739	0.261	0.000
S69 Other and unspecified injuries of wrist and hand	0.736	0.264	0.000
V19 Pedal cyclist injured in other and unspecified transport accidents	0.735	0.265	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.734	0.266	0.000
G70-G73 Diseases of myoneural junction and muscle	0.734	0.266	0.000
G95 Other diseases of spinal cord	0.734	0.266	0.000
V43 Car occupant injured in collision with car, pick-up truck or van	0.733	0.267	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.733	0.267	0.000
L21 Seborrhoeic dermatitis	0.732	0.267	0.000
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident	0.732	0.268	0.000
G25.0 Essential tremor	0.730	0.270	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.728	0.272	0.000
W10 Fall on and from stairs and steps	0.727	0.273	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.726	0.274	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.726	0.274	0.000
W18.3 Sports and athletics area	0.725	0.275	0.000
E80.1 Porphyria cutanea tarda	0.724	0.276	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.722	0.278	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.719	0.281	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.718	0.282	0.000
T66 Unspecified effects of radiation	0.718	0.282	0.000
G36 Other acute disseminated demyelination	0.717	0.283	0.000
W15 Fall from cliff	0.716	0.283	0.000
Y57 Other and unspecified drugs and medicaments	0.715	0.285	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.715	0.285	0.000
S67 Crushing injury of wrist and hand	0.715	0.285	0.000
K74.3 Primary biliary cirrhosis	0.715	0.285	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.714	0.286	0.000
Y35-Y36 Legal intervention and operations of war	0.714	0.286	0.000
Y10-Y34 Event of undetermined intent	0.714	0.286	0.000
X85-X99 Assault	0.714	0.286	0.000
X30-X39 Exposure to forces of nature	0.714	0.286	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.714	0.286	0.000
W75-W84 Other accidental threats to breathing	0.714	0.286	0.000
W65-W74 Accidental drowning and submersion	0.714	0.286	0.000
V98-V99 Other and unspecified transport accidents	0.714	0.286	0.000
V90-V94 Water transport accidents	0.714	0.286	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.714	0.286	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.714	0.286	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.714	0.286	0.000
V01-V09 Pedestrian injured in transport accident	0.714	0.286	0.000
Q27 Other congenital malformations of peripheral vascular system	0.713	0.287	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.712	0.287	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.712	0.288	0.000
F00 Dementia in Alzheimer's disease	0.711	0.289	0.000
F69 Unspecified disorder of adult personality and behaviour	0.710	0.290	0.000
S09 Other and unspecified injuries of head	0.710	0.290	0.000
G24.3 Spasmodic torticollis	0.710	0.290	0.000
L30.8 Other specified dermatitis	0.709	0.291	0.000
X10-X19 Contact with heat and hot substances	0.708	0.292	0.000
W07 Fall involving chair	0.708	0.292	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.706	0.294	0.000
L10-L14 Bullous disorders	0.705	0.295	0.000
G23 Other degenerative diseases of basal ganglia	0.704	0.296	0.000
G21 Secondary Parkinsonism	0.704	0.296	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.704	0.296	0.000
G22 Parkinsonism in diseases classified elsewhere	0.704	0.296	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.704	0.296	0.000
K41 Femoral hernia	0.703	0.297	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.703	0.297	0.000
W14 Fall from tree	0.703	0.297	0.000
W12 Fall on and from scaffolding	0.703	0.297	0.000
W09 Fall involving playground equipment	0.703	0.297	0.000
W05 Fall involving wheelchair	0.703	0.297	0.000
W04 Fall while being carried or supported by other persons	0.703	0.297	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.703	0.297	0.000
W00 Fall on same level involving ice and snow	0.703	0.297	0.000
Q89 Other congenital malformations, not elsewhere classified	0.702	0.298	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.701	0.298	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.701	0.299	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.700	0.299	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.700	0.300	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.699	0.300	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.699	0.301	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.699	0.301	0.000
F01 Vascular dementia	0.697	0.303	0.000
K77 Liver disorders in diseases classified elsewhere	0.696	0.304	0.000
K71 Toxic liver disease	0.696	0.304	0.000
L04 Acute lymphadenitis	0.695	0.305	0.000
L01 Impetigo	0.695	0.305	0.000
L00 Staphylococcal scalded skin syndrome	0.695	0.305	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.695	0.305	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.694	0.306	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.692	0.307	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.691	0.308	0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.690	0.310	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.689	0.310	0.000
K51.9 Ulcerative colitis, unspecified	0.689	0.311	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.688	0.312	0.000
K76.5 Hepatic veno-occlusive disease	0.688	0.312	0.000
K76.4 Peliosis hepatis	0.688	0.312	0.000
K76.3 Infarction of liver	0.688	0.312	0.000
K76.2 Central haemorrhagic necrosis of liver	0.688	0.312	0.000
K76.1 Chronic passive congestion of liver	0.688	0.312	0.000
F10.6 Amnesic syndrome	0.688	0.312	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.687	0.313	0.000
G24.8 Other dystonia	0.685	0.315	0.000
Q25 Congenital malformations of great arteries	0.685	0.315	0.000
Y59 Other and unspecified vaccines and biological substances	0.685	0.315	0.000
Y58 Bacterial vaccines	0.685	0.315	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.685	0.315	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.685	0.315	0.000
S65 Injury of blood vessels at wrist and hand level	0.682	0.318	0.000
Y45.2 Propionic acid derivatives	0.681	0.318	0.000
W11 Fall on and from ladder	0.679	0.321	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.678	0.322	0.000
W08 Fall involving other furniture	0.678	0.322	0.000
E00-E07 Disorders of thyroid gland	0.678	0.322	0.000
Q24 Other congenital malformations of heart	0.678	0.322	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.677	0.322	0.000
K74.4 Secondary biliary cirrhosis	0.677	0.323	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.677	0.323	0.000
K74.1 Hepatic sclerosis	0.677	0.323	0.000
G41 Status epilepticus	0.677	0.323	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.677	0.323	0.000
V47 Car occupant injured in collision with fixed or stationary object	0.677	0.323	0.000
V46 Car occupant injured in collision with other nonmotor vehicle	0.677	0.323	0.000
V45 Car occupant injured in collision with railway train or railway vehicle	0.677	0.323	0.000
V42 Car occupant injured in collision with two- or three-wheeled motor vehicle	0.677	0.323	0.000
V41 Car occupant injured in collision with pedal cycle	0.677	0.323	0.000
V40 Car occupant injured in collision with pedestrian or animal	0.677	0.323	0.000
W18.5 Trade and service area	0.677	0.323	0.000
K74.5 Biliary cirrhosis, unspecified	0.675	0.325	0.000
S06 Intracranial injury	0.675	0.325	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.674	0.326	0.000
K70.9 Alcoholic liver disease, unspecified	0.673	0.327	0.000
F11 Mental and behavioural disorders due to use of opioids	0.672	0.327	0.000
Y45.5 4-Aminophenol derivatives	0.672	0.328	0.000
F64 Gender identity disorders	0.671	0.329	0.000
L40-L45 Papulosquamous disorders	0.523	0.329	0.149
T91.3 Sequelae of injury of spinal cord	0.671	0.329	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.670	0.330	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.669	0.330	0.000
X60-X84 Intentional self-harm	0.669	0.331	0.000
Y49.2 Other and unspecified antidepressants	0.669	0.331	0.000
Q00-Q07 Congenital malformations of the nervous system	0.669	0.331	0.000
F60.9 Personality disorder, unspecified	0.668	0.332	0.000
G91 Hydrocephalus	0.668	0.332	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.668	0.332	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.668	0.332	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.668	0.332	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.668	0.332	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.668	0.332	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.668	0.332	0.000
G30.9 Alzheimer's disease, unspecified	0.668	0.332	0.000
Q23.1 Congenital insufficiency of aortic valve	0.667	0.333	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.666	0.334	0.000
F10.4 Withdrawal state with delirium	0.665	0.335	0.000
E89.3 Postprocedural hypopituitarism	0.665	0.335	0.000
G95.0 Syringomyelia and syringobulbia	0.665	0.335	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.663	0.337	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.663	0.337	0.000
E83.8 Other disorders of mineral metabolism	0.663	0.337	0.000
E83.2 Disorders of zinc metabolism	0.663	0.337	0.000
E83.0 Disorders of copper metabolism	0.663	0.337	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.663	0.337	0.000
G30.8 Other Alzheimer's disease	0.662	0.338	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.662	0.338	0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus	0.662	0.338	0.000
G30.0 Alzheimer's disease with early onset	0.662	0.338	0.000
I80 Phlebitis and thrombophlebitis	0.660	0.340	0.000
W01.1 Residential institution	0.660	0.340	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.659	0.341	0.000
G25.5 Other chorea	0.659	0.341	0.000
G25.4 Drug-induced chorea	0.659	0.341	0.000
G25.2 Other specified forms of tremor	0.659	0.341	0.000
G25.1 Drug-induced tremor	0.659	0.341	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.659	0.341	0.000
V20-V29 Motorcycle rider injured in transport accident	0.658	0.342	0.000
E84 Cystic fibrosis	0.657	0.342	0.000
E79 Disorders of purine and pyrimidine metabolism	0.657	0.342	0.000
E77 Disorders of glycoprotein metabolism	0.657	0.342	0.000
E76 Disorders of glycosaminoglycan metabolism	0.657	0.342	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.657	0.342	0.000
E72 Other disorders of amino-acid metabolism	0.657	0.342	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.657	0.342	0.000
E70 Disorders of aromatic amino-acid metabolism	0.657	0.342	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.657	0.342	0.000
F10.8 Other mental and behavioural disorders	0.657	0.343	0.000
F10.7 Residual and late-onset psychotic disorder	0.657	0.343	0.000
L24 Irritant contact dermatitis	0.657	0.343	0.000
L23 Allergic contact dermatitis	0.657	0.343	0.000
L26 Exfoliative dermatitis	0.657	0.343	0.000
L22 Diaper [napkin] dermatitis	0.657	0.343	0.000
W17.4 Street and highway	0.656	0.344	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.656	0.344	0.000
I88 Nonspecific lymphadenitis	0.654	0.346	0.000
G47.2 Disorders of the sleep-wake schedule	0.654	0.346	0.000
T33-T35 Frostbite	0.653	0.346	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.653	0.346	0.000
T00-T07 Injuries involving multiple body regions	0.653	0.346	0.000
L25 Unspecified contact dermatitis	0.652	0.348	0.000
Q82 Other congenital malformations of skin	0.652	0.348	0.000
Y45.8 Other analgesics and antipyretics	0.652	0.348	0.000
F10.1 Harmful use	0.652	0.348	0.000
F99 Mental disorder, not otherwise specified	0.652	0.348	0.000
G24.5 Blepharospasm	0.651	0.349	0.000
Y47.1 Benzodiazepines	0.651	0.349	0.000
W17.5 Trade and service area	0.651	0.349	0.000
W19.8 Other specified place	0.649	0.351	0.000
W19.5 Trade and service area	0.649	0.351	0.000
W19.0 Home	0.649	0.351	0.000
W19.7 Farm	0.649	0.351	0.000
W19.6 Industrial and construction area	0.649	0.351	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.649	0.351	0.000
Y40.7 Antifungal antibiotics, systemically used	0.649	0.351	0.000
Y40.6 Rifamycins	0.649	0.351	0.000
Y40.5 Aminoglycosides	0.649	0.351	0.000
Y40.4 Tetracyclines	0.649	0.351	0.000
Y40.3 Macrolides	0.649	0.351	0.000
Y40.2 Chloramphenicol group	0.649	0.351	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.647	0.353	0.000
S61 Open wound of wrist and hand	0.646	0.354	0.000
S00.5 Superficial injury of lip and oral cavity	0.645	0.355	0.000
L05 Pilonidal cyst	0.645	0.355	0.000
L29 Pruritus	0.644	0.356	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.644	0.356	0.000
G95.2 Cord compression, unspecified	0.644	0.356	0.000
L40 Psoriasis	0.018	0.357	0.625
S14 Injury of nerves and spinal cord at neck level	0.642	0.358	0.000
I27 Other pulmonary heart diseases	0.642	0.358	0.000
G44.2 Tension-type headache	0.642	0.358	0.000
S90-S99 Injuries to the ankle and foot	0.642	0.358	0.000
W17.6 Industrial and construction area	0.641	0.358	0.000
Q35-Q37 Cleft lip and cleft palate	0.641	0.358	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.641	0.358	0.000
E83.3 Disorders of phosphorus metabolism	0.641	0.359	0.000
K72 Hepatic failure, not elsewhere classified	0.641	0.359	0.000
T68 Hypothermia	0.641	0.359	0.000
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident	0.639	0.361	0.000
K51.5 Mucosal proctocolitis	0.638	0.362	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.638	0.362	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.637	0.363	0.000
V80.9 Rider or occupant injured in other and unspecified transport accidents	0.637	0.363	0.000
L03.0 Cellulitis of finger and toe	0.635	0.365	0.000
F68 Other disorders of adult personality and behaviour	0.635	0.365	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.635	0.365	0.000
F65 Disorders of sexual preference	0.635	0.365	0.000
F63 Habit and impulse disorders	0.635	0.365	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.635	0.365	0.000
F61 Mixed and other personality disorders	0.635	0.365	0.000
T93.0 Sequelae of open wound of lower limb	0.635	0.365	0.000
F09 Unspecified organic or symptomatic mental disorder	0.634	0.366	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.634	0.366	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.634	0.366	0.000
V49.8 Car occupant [any] injured in other specified transport accidents	0.634	0.366	0.000
V49.6 Unspecified car occupant injured in collision with other and unspecified motor vehicles in traffic accident	0.634	0.366	0.000
V49.5 Passenger injured in collision with other and unspecified motor vehicles in traffic accident	0.634	0.366	0.000
V49.3 Car occupant [any] injured in unspecified nontraffic accident	0.634	0.366	0.000
V49.2 Unspecified car occupant injured in collision with other and unspecified motor vehicles in nontraffic accident	0.634	0.366	0.000
V49.1 Passenger injured in collision with other and unspecified motor vehicles in nontraffic accident	0.634	0.366	0.000
V49.0 Driver injured in collision with other and unspecified motor vehicles in nontraffic accident	0.634	0.366	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.633	0.366	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.633	0.366	0.000
E89.5 Postprocedural testicular hypofunction	0.633	0.366	0.000
E89.4 Postprocedural ovarian failure	0.633	0.366	0.000
E89.1 Postprocedural hypoinsulinaemia	0.633	0.366	0.000
E04 Other non-toxic goitre	0.631	0.369	0.000
I00-I02 Acute rheumatic fever	0.630	0.370	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.629	0.371	0.000
L40.9 Psoriasis, unspecified	0.000	0.371	0.629
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.629	0.371	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.629	0.371	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.628	0.372	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.628	0.372	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.628	0.372	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.628	0.372	0.000
Q89.2 Congenital malformations of other endocrine glands	0.628	0.372	0.000
W13 Fall from, out of or through building or structure	0.627	0.373	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.626	0.374	0.000
Y45.4 Antirheumatics	0.626	0.374	0.000
S06.3 Focal brain injury	0.625	0.375	0.000
T90.4 Sequelae of injury of eye and orbit	0.624	0.376	0.000
L40.5 Arthropathic psoriasis	0.001	0.377	0.622
I85 Oesophageal varices	0.623	0.377	0.000
V17 Pedal cyclist injured in collision with fixed or stationary object	0.622	0.377	0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle	0.622	0.377	0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle	0.622	0.377	0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus	0.622	0.377	0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van	0.622	0.377	0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle	0.622	0.377	0.000
V11 Pedal cyclist injured in collision with other pedal cycle	0.622	0.377	0.000
V10 Pedal cyclist injured in collision with pedestrian or animal	0.622	0.377	0.000
G24.9 Dystonia, unspecified	0.623	0.377	0.000
Y48 Anaesthetics and therapeutic gases	0.622	0.378	0.000
W19.1 Residential institution	0.622	0.378	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.622	0.378	0.000
F05.9 Delirium, unspecified	0.621	0.379	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.621	0.379	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.621	0.379	0.000
T95 Sequelae of burns, corrosions and frostbite	0.620	0.380	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.620	0.380	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.620	0.380	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.620	0.380	0.000
K73 Chronic hepatitis, not elsewhere classified	0.620	0.380	0.000
S00.7 Multiple superficial injuries of head	0.620	0.380	0.000
V88 Nontraffic accident of specified type but victim's mode of transport unknown	0.619	0.380	0.000
V87 Traffic accident of specified type but victim's mode of transport unknown	0.619	0.380	0.000
V86 Occupant of special all-terrain or other motor vehicle designed primarily for off-road use, injured in transport accident	0.619	0.380	0.000
V85 Occupant of special construction vehicle injured in transport accident	0.619	0.380	0.000
V84 Occupant of special vehicle mainly used in agriculture injured in transport accident	0.619	0.380	0.000
V83 Occupant of special vehicle mainly used on industrial premises injured in transport accident	0.619	0.380	0.000
V82 Occupant of streetcar injured in transport accident	0.619	0.380	0.000
V81 Occupant of railway train or railway vehicle injured in transport accident	0.619	0.380	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.619	0.381	0.000
K51.4 Pseudopolyposis of colon	0.619	0.381	0.000
F60.7 Dependent personality disorder	0.618	0.382	0.000
G31.8 Other specified degenerative diseases of nervous system	0.617	0.383	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.616	0.384	0.000
T70 Effects of air pressure and water pressure	0.616	0.384	0.000
G24.4 Idiopathic orofacial dystonia	0.616	0.384	0.000
G24.2 Idiopathic nonfamilial dystonia	0.616	0.384	0.000
G24.1 Idiopathic familial dystonia	0.616	0.384	0.000
G24.0 Drug-induced dystonia	0.616	0.384	0.000
W06.0 Home	0.615	0.385	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.614	0.385	0.000
T75 Effects of other external causes	0.614	0.386	0.000
T74 Maltreatment syndromes	0.614	0.386	0.000
T73 Effects of other deprivation	0.614	0.386	0.000
T69 Other effects of reduced temperature	0.614	0.386	0.000
T67 Effects of heat and light	0.614	0.386	0.000
T71 Asphyxiation	0.614	0.386	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.613	0.387	0.000
Y44.2 Anticoagulants	0.613	0.387	0.000
L20.9 Atopic dermatitis, unspecified	0.613	0.387	0.000
V48.4 Person injured while boarding or alighting	0.613	0.387	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.612	0.388	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.612	0.388	0.000
S00.3 Superficial injury of nose	0.612	0.388	0.000
W18.9 Unspecified place	0.611	0.389	0.000
W18.8 Other specified place	0.611	0.389	0.000
W18.4 Street and highway	0.611	0.389	0.000
W18.2 School, other institution and public administrative area	0.611	0.389	0.000
W18.0 Home	0.611	0.389	0.000
W18.7 Farm	0.611	0.389	0.000
W18.6 Industrial and construction area	0.611	0.389	0.000
W18.1 Residential institution	0.611	0.389	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.611	0.389	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.610	0.390	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.610	0.390	0.000
L28.1 Prurigo nodularis	0.609	0.391	0.000
L03.8 Cellulitis of other sites	0.608	0.392	0.000
Q26 Congenital malformations of great veins	0.607	0.393	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.607	0.393	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.607	0.393	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.607	0.393	0.000
G25.3 Myoclonus	0.607	0.393	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.607	0.393	0.000
X20-X29 Contact with venomous animals and plants	0.605	0.395	0.000
T78.2 Anaphylactic shock, unspecified	0.605	0.395	0.000
F02 Dementia in other diseases classified elsewhere	0.605	0.395	0.000
L28.0 Lichen simplex chronicus	0.604	0.396	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.603	0.397	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.603	0.397	0.000
Y46.2 Hydantoin derivatives	0.602	0.398	0.000
K76.9 Liver disease, unspecified	0.602	0.398	0.000
G00 Bacterial meningitis, not elsewhere classified	0.601	0.399	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.601	0.399	0.000
Y57.8 Other drugs and medicaments	0.601	0.399	0.000
E74 Other disorders of carbohydrate metabolism	0.600	0.400	0.000
V96 Accident to nonpowered aircraft causing injury to occupant	0.599	0.400	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.599	0.401	0.000
E04.2 Non-toxic multinodular goitre	0.599	0.401	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations