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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13224671
log Bayes Factor = 5.17412
Chromosome 7   position 6,736,332  (GRCh37) Explore rs13224671 on Ensembl!
Variant rs13224671 is part of Cluster X0191

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
0.999 0.001 0.000
S00-S09 Injuries to the head
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
Chapter V Mental and behavioural disorders
0.988 0.012 0.000
M54 Dorsalgia
0.988 0.012 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.987 0.013 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.986 0.014 0.000
M50-M54 Other dorsopathies
0.986 0.014 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.986 0.014 0.000
I63 Cerebral infarction
0.986 0.014 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.985 0.015 0.000
M54.5 Low back pain
0.984 0.016 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.984 0.016 0.000
Chapter XI Diseases of the digestive system
0.981 0.019 0.000
K86 Other diseases of pancreas
0.981 0.019 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.980 0.020 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.979 0.021 0.000
S06 Intracranial injury
0.978 0.022 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.977 0.023 0.000
I65.2 Occlusion and stenosis of carotid artery
0.976 0.024 0.000
K86.1 Other chronic pancreatitis
0.974 0.026 0.000
M54.59 Low back pain (Site unspecified)
0.970 0.030 0.000
M51 Other intervertebral disk disorders
0.968 0.032 0.000
G40-G47 Episodic and paroxysmal disorders
0.967 0.033 0.000
I77 Other disorders of arteries and arterioles
0.967 0.033 0.000
I63.9 Cerebral infarction, unspecified
0.966 0.034 0.000
K82 Other diseases of gallbladder
0.954 0.046 0.000
M51.2 Other specified intervertebral disk displacement
0.954 0.046 0.000
F10.3 Withdrawal state
0.954 0.046 0.000
F10.2 Dependence syndrome
0.952 0.048 0.000
K82.8 Other specified diseases of gallbladder
0.948 0.052 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.939 0.061 0.000
I10-I15 Hypertensive diseases
0.935 0.065 0.000
K85 Acute pancreatitis
0.934 0.066 0.000
K70-K77 Diseases of liver
0.934 0.066 0.000
I77.1 Stricture of artery
0.927 0.073 0.000
S80-S89 Injuries to the knee and lower leg
0.923 0.077 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.922 0.078 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.922 0.078 0.000
M54.3 Sciatica
0.919 0.081 0.000
G43 Migraine
0.918 0.082 0.000
M54.1 Radiculopathy
0.914 0.086 0.000
I12 Hypertensive renal disease
0.909 0.091 0.000
S01 Open wound of head
0.907 0.093 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.905 0.095 0.000
R40 Somnolence, stupor and coma
0.900 0.100 0.000
G47 Sleep disorders
0.898 0.102 0.000
S05 Injury of eye and orbit
0.897 0.103 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.894 0.106 0.000
T79-T79 Certain early complications of trauma
0.894 0.106 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.893 0.107 0.000
I60 Subarachnoid haemorrhage
0.893 0.107 0.000
K70 Alcoholic liver disease
0.893 0.107 0.000
T93 Sequelae of injuries of lower limb
0.893 0.107 0.000
S82 Fracture of lower leg, including ankle
0.892 0.108 0.000
T90 Sequelae of injuries of head
0.890 0.110 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.888 0.112 0.000
I73 Other peripheral vascular diseases
0.888 0.112 0.000
I69 Sequelae of cerebrovascular disease
0.886 0.114 0.000
I12.0 Hypertensive renal disease with renal failure
0.884 0.116 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.884 0.116 0.000
G47.9 Sleep disorder, unspecified
0.879 0.121 0.000
G43.9 Migraine, unspecified
0.879 0.121 0.000
S06.5 Traumatic subdural haemorrhage
0.878 0.122 0.000
K86.3 Pseudocyst of pancreas
0.877 0.123 0.000
S82.8 Fractures of other parts of lower leg
0.877 0.123 0.000
K85.9 Acute pancreatitis, unspecified
0.874 0.126 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.873 0.127 0.000
T91 Sequelae of injuries of neck and trunk
0.872 0.128 0.000
S06.3 Focal brain injury
0.872 0.128 0.000
M54.39 Sciatica (Site unspecified)
0.869 0.131 0.000
R40.2 Coma, unspecified
0.868 0.132 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.866 0.134 0.000
S01.0 Open wound of scalp
0.866 0.134 0.000
M54.57 Low back pain (Lumbosacral region)
0.857 0.143 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.854 0.146 0.000
M54.56 Low back pain (Lumbar region)
0.849 0.151 0.000
F10.5 Psychotic disorder
0.848 0.152 0.000
Q23 Congenital malformations of aortic and mitral valves
0.845 0.155 0.000
M54.16 Radiculopathy (Lumbar region)
0.845 0.155 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.843 0.157 0.000
F10.1 Harmful use
0.841 0.159 0.000
S06.9 Intracranial injury, unspecified
0.841 0.159 0.000
K81 Cholecystitis
0.841 0.159 0.000
I73.9 Peripheral vascular disease, unspecified
0.838 0.162 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.836 0.164 0.000
G90-G99 Other disorders of the nervous system
0.836 0.164 0.000
S01.8 Open wound of other parts of head
0.833 0.167 0.000
S82.2 Fracture of shaft of tibia
0.831 0.169 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.830 0.170 0.000
K86.9 Disease of pancreas, unspecified
0.829 0.171 0.000
K70.9 Alcoholic liver disease, unspecified
0.826 0.174 0.000
K65-K67 Diseases of peritoneum
0.826 0.174 0.000
G81 Hemiplegia
0.823 0.177 0.000
S40-S49 Injuries to the shoulder and upper arm
0.822 0.178 0.000
S02 Fracture of skull and facial bones
0.822 0.178 0.000
M54.9 Dorsalgia, unspecified
0.819 0.181 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.818 0.182 0.000
Q25 Congenital malformations of great arteries
0.815 0.185 0.000
S06.2 Diffuse brain injury
0.813 0.187 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.812 0.188 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.812 0.188 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.811 0.189 0.000
F10.9 Unspecified mental and behavioural disorder
0.811 0.189 0.000
Q60-Q64 Congenital malformations of the urinary system
0.811 0.189 0.000
I67 Other cerebrovascular diseases
0.807 0.193 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.806 0.194 0.000
R45 Symptoms and signs involving emotional state
0.804 0.196 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.796 0.204 0.000
G20-G26 Extrapyramidal and movement disorders
0.789 0.211 0.000
K82.9 Disease of gallbladder, unspecified
0.788 0.212 0.000
S82.20 Fracture of shaft of tibia (closed)
0.784 0.216 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.782 0.218 0.000
I15 Secondary hypertension
0.779 0.221 0.000
Q23.1 Congenital insufficiency of aortic valve
0.778 0.222 0.000
I70 Atherosclerosis
0.776 0.224 0.000
G44 Other headache syndromes
0.774 0.226 0.000
M54.50 Low back pain (Multiple sites in spine)
0.773 0.227 0.000
K85.8 Other acute pancreatitis
0.772 0.228 0.000
G81.9 Hemiplegia, unspecified
0.772 0.228 0.000
K75 Other inflammatory liver diseases
0.770 0.230 0.000
R40.0 Somnolence
0.769 0.231 0.000
M91-M94 Chondropathies
0.769 0.231 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.767 0.233 0.000
T90.5 Sequelae of intracranial injury
0.766 0.234 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.766 0.234 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.766 0.234 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.765 0.235 0.000
Q50-Q56 Congenital malformations of genital organs
0.763 0.237 0.000
Q27 Other congenital malformations of peripheral vascular system
0.763 0.237 0.000
S42 Fracture of shoulder and upper arm
0.758 0.242 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.755 0.245 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.753 0.247 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.752 0.248 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.747 0.253 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.747 0.253 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.746 0.254 0.000
R20 Disturbances of skin sensation
0.746 0.254 0.000
S09 Other and unspecified injuries of head
0.745 0.255 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.745 0.255 0.000
M54.6 Pain in thoracic spine
0.743 0.257 0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)
0.743 0.257 0.000
S05.9 Injury of eye and orbit, part unspecified
0.743 0.257 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.741 0.259 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.740 0.260 0.000
I77.0 Arteriovenous fistula, acquired
0.740 0.260 0.000
K73 Chronic hepatitis, not elsewhere classified
0.740 0.260 0.000
S06.0 Concussion
0.740 0.260 0.000
G70-G73 Diseases of myoneural junction and muscle
0.740 0.260 0.000
I78 Diseases of capillaries
0.738 0.261 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.738 0.262 0.000
K74 Fibrosis and cirrhosis of liver
0.738 0.262 0.000
K70.3 Alcoholic cirrhosis of liver
0.735 0.265 0.000
M54.37 Sciatica (Lumbosacral region)
0.735 0.265 0.000
T93.0 Sequelae of open wound of lower limb
0.732 0.268 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.732 0.268 0.000
R44.3 Hallucinations, unspecified
0.731 0.269 0.000
F70-F79 Mental retardation
0.730 0.270 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.730 0.270 0.000
I67.1 Cerebral aneurysm, nonruptured
0.730 0.270 0.000
S90-S99 Injuries to the ankle and foot
0.729 0.271 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.728 0.272 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.728 0.272 0.000
G95 Other diseases of spinal cord
0.727 0.273 0.000
G25 Other extrapyramidal and movement disorders
0.725 0.275 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.724 0.276 0.000
M86-M90 Other osteopathies
0.724 0.276 0.000
M51.8 Other specified intervertebral disk disorders
0.723 0.277 0.000
M54.4 Lumbago with sciatica
0.723 0.277 0.000
R29.6 Tendency to fall, not elsewhere classified
0.722 0.278 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.722 0.278 0.000
I05-I09 Chronic rheumatic heart diseases
0.722 0.278 0.000
T00-T07 Injuries involving multiple body regions
0.720 0.279 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.720 0.280 0.000
S05.1 Contusion of eyeball and orbital tissues
0.720 0.280 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.720 0.280 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.718 0.282 0.000
S02.2 Fracture of nasal bones
0.717 0.283 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.283 0.000
Q28 Other congenital malformations of circulatory system
0.716 0.284 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.716 0.284 0.000
M54.12 Radiculopathy (Cervical region)
0.716 0.284 0.000
R20.2 Paraesthesia of skin
0.716 0.284 0.000
Q61 Cystic kidney disease
0.714 0.286 0.000
S08 Traumatic amputation of part of head
0.714 0.286 0.000
S07 Crushing injury of head
0.714 0.286 0.000
S04 Injury of cranial nerves
0.714 0.286 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.714 0.286 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.714 0.286 0.000
M40-M43 Deforming dorsopathies
0.713 0.287 0.000
S06.4 Epidural haemorrhage
0.712 0.287 0.000
T51 Toxic effect of alcohol
0.712 0.288 0.000
F10.4 Withdrawal state with delirium
0.712 0.288 0.000
I12.9 Hypertensive renal disease without renal failure
0.711 0.289 0.000
K81.9 Cholecystitis, unspecified
0.710 0.290 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.709 0.291 0.000
M54.8 Other dorsalgia
0.708 0.291 0.000
M54.0 Panniculitis affecting regions of neck and back
0.708 0.291 0.000
K70.0 Alcoholic fatty liver
0.708 0.292 0.000
R45.1 Restlessness and agitation
0.708 0.292 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.707 0.293 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.707 0.293 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.707 0.293 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.707 0.293 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.707 0.293 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.707 0.293 0.000
F10.8 Other mental and behavioural disorders
0.707 0.293 0.000
F10.7 Residual and late-onset psychotic disorder
0.707 0.293 0.000
F10.6 Amnesic syndrome
0.707 0.293 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.707 0.293 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.707 0.293 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.707 0.293 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.706 0.293 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.706 0.293 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.706 0.293 0.000
I65.1 Occlusion and stenosis of basilar artery
0.706 0.293 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.706 0.293 0.000
M54.54 Low back pain-Thoracic
0.706 0.294 0.000
M54.53 Low back pain-Cervicothoracic
0.706 0.294 0.000
M54.52 Low back pain-Cervical
0.706 0.294 0.000
M54.51 Low back pain-Occipit-atl-axl
0.706 0.294 0.000
Q00-Q07 Congenital malformations of the nervous system
0.706 0.294 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.705 0.295 0.000
G90 Disorders of autonomic nervous system
0.705 0.295 0.000
T79.8 Other early complications of trauma
0.705 0.295 0.000
T90.1 Sequelae of open wound of head
0.702 0.298 0.000
T95 Sequelae of burns, corrosions and frostbite
0.702 0.298 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.702 0.298 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.702 0.298 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.702 0.298 0.000
S06.7 Intracranial injury with prolonged coma
0.701 0.298 0.000
S06.1 Traumatic cerebral oedema
0.701 0.298 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.700 0.299 0.000
Q35-Q37 Cleft lip and cleft palate
0.700 0.299 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.700 0.299 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.700 0.300 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.700 0.300 0.000
K85.2 Alcohol-induced acute pancreatitis
0.698 0.302 0.000
S05.8 Other injuries of eye and orbit
0.697 0.303 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.697 0.303 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.697 0.303 0.000
R47-R49 Symptoms and signs involving speech and voice
0.697 0.303 0.000
M51.9 Intervertebral disk disorder, unspecified
0.694 0.306 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.694 0.306 0.000
M51.3 Other specified intervertebral disk degeneration
0.694 0.306 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.694 0.306 0.000
M51.4 Schmorl's nodes
0.694 0.306 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.693 0.306 0.000
I77.5 Necrosis of artery
0.693 0.306 0.000
I77.4 Coeliac artery compression syndrome
0.693 0.306 0.000
I77.3 Arterial fibromuscular dysplasia
0.693 0.306 0.000
I77.2 Rupture of artery
0.693 0.306 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.693 0.306 0.000
K70.4 Alcoholic hepatic failure
0.693 0.306 0.000
S86 Injury of muscle and tendon at lower leg level
0.693 0.307 0.000
K81.1 Chronic cholecystitis
0.692 0.308 0.000
K65 Peritonitis
0.692 0.308 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.691 0.308 0.000
R41.2 Retrograde amnesia
0.691 0.309 0.000
I77.6 Arteritis, unspecified
0.690 0.310 0.000
M54.55 Low back pain (Thoracolumbar region)
0.689 0.310 0.000
R46 Symptoms and signs involving appearance and behaviour
0.689 0.311 0.000
S06.8 Other intracranial injuries
0.687 0.313 0.000
K35-K38 Diseases of appendix
0.687 0.313 0.000
M60-M63 Disorders of muscles
0.686 0.314 0.000
G43.1 Migraine with aura [classical migraine]
0.685 0.315 0.000
K82.3 Fistula of gallbladder
0.684 0.316 0.000
K82.0 Obstruction of gallbladder
0.684 0.316 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.684 0.316 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.683 0.317 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.682 0.317 0.000
G96 Other disorders of central nervous system
0.682 0.317 0.000
G83 Other paralytic syndromes
0.682 0.318 0.000
R41.0 Disorientation, unspecified
0.681 0.319 0.000
M00-M03 Infectious arthropathies
0.679 0.321 0.000
T17 Foreign body in respiratory tract
0.678 0.322 0.000
I72 Other aneurysm
0.678 0.322 0.000
S40 Superficial injury of shoulder and upper arm
0.674 0.326 0.000
Q25.1 Coarctation of aorta
0.674 0.326 0.000
S42.3 Fracture of shaft of humerus
0.673 0.327 0.000
T90.4 Sequelae of injury of eye and orbit
0.673 0.327 0.000
Q26 Congenital malformations of great veins
0.673 0.327 0.000
Q24 Other congenital malformations of heart
0.673 0.327 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.673 0.327 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.673 0.327 0.000
T92 Sequelae of injuries of upper limb
0.673 0.327 0.000
M53 Other dorsopathies, not elsewhere classified
0.672 0.327 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.672 0.328 0.000
M80-M85 Disorders of bone density and structure
0.671 0.329 0.000
F60-F69 Disorders of adult personality and behaviour
0.671 0.329 0.000
I13 Hypertensive heart and renal disease
0.671 0.329 0.000
Q25.0 Patent ductus arteriosus
0.670 0.330 0.000
K85.3 Drug-induced acute pancreatitis
0.670 0.330 0.000
K85.0 Idiopathic acute pancreatitis
0.670 0.330 0.000
K77 Liver disorders in diseases classified elsewhere
0.670 0.330 0.000
K71 Toxic liver disease
0.670 0.330 0.000
R25 Abnormal involuntary movements
0.669 0.331 0.000
S02.0 Fracture of vault of skull
0.668 0.332 0.000
K75.0 Abscess of liver
0.667 0.332 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.666 0.334 0.000
G00 Bacterial meningitis, not elsewhere classified
0.666 0.334 0.000
T23 Burn and corrosion of wrist and hand
0.666 0.334 0.000
S10-S19 Injuries to the neck
0.666 0.334 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.666 0.334 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.665 0.335 0.000
T91.3 Sequelae of injury of spinal cord
0.664 0.336 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.662 0.338 0.000
S88 Traumatic amputation of lower leg
0.661 0.338 0.000
S87 Crushing injury of lower leg
0.661 0.338 0.000
S85 Injury of blood vessels at lower leg level
0.661 0.338 0.000
S84 Injury of nerves at lower leg level
0.661 0.338 0.000
S20-S29 Injuries to the thorax
0.661 0.338 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.661 0.339 0.000
I11 Hypertensive heart disease
0.661 0.339 0.000
R43 Disturbances of smell and taste
0.661 0.339 0.000
S82.5 Fracture of medial malleolus
0.660 0.339 0.000
F30-F39 Mood [affective] disorders
0.660 0.340 0.000
I74 Arterial embolism and thrombosis
0.660 0.340 0.000
F11 Mental and behavioural disorders due to use of opioids
0.659 0.341 0.000
Q80-Q89 Other congenital malformations
0.659 0.341 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.659 0.341 0.000
M54.35 Sciatica (Thoracolumbar region)
0.659 0.341 0.000
M54.34 Sciatica-Thoracic
0.659 0.341 0.000
M54.33 Sciatica-Cervicothoracic
0.659 0.341 0.000
M54.32 Sciatica-Cervical
0.659 0.341 0.000
M54.31 Sciatica-Occipit-atl-axl
0.659 0.341 0.000
M54.30 Sciatica (Multiple sites in spine)
0.659 0.341 0.000
G43.8 Other migraine
0.658 0.342 0.000
G43.3 Complicated migraine
0.658 0.342 0.000
G43.2 Status migrainosus
0.658 0.342 0.000
G43.0 Migraine without aura [common migraine]
0.658 0.342 0.000
T93.1 Sequelae of fracture of femur
0.658 0.342 0.000
S50-S59 Injuries to the elbow and forearm
0.656 0.344 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.655 0.345 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.655 0.345 0.000
M54.14 Radiculopathy (Thoracic region)
0.655 0.345 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.655 0.345 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.655 0.345 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.655 0.345 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.655 0.345 0.000
G91 Hydrocephalus
0.652 0.348 0.000
K85.1 Biliary acute pancreatitis
0.651 0.349 0.000
I69.3 Sequelae of cerebral infarction
0.650 0.350 0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified
0.649 0.350 0.000
S42.1 Fracture of scapula
0.649 0.351 0.000
T51.0 Ethanol
0.649 0.351 0.000
G03 Meningitis due to other and unspecified causes
0.648 0.352 0.000
T91.1 Sequelae of fracture of spine
0.648 0.352 0.000
F99-F99 Unspecified mental disorder
0.648 0.352 0.000
Q61.3 Polycystic kidney, unspecified
0.648 0.352 0.000
F17.2 Dependence syndrome
0.647 0.353 0.000
R40.1 Stupor
0.645 0.355 0.000
S02.1 Fracture of base of skull
0.644 0.356 0.000
I61 Intracerebral haemorrhage
0.644 0.356 0.000
G47.8 Other sleep disorders
0.644 0.356 0.000
G47.4 Narcolepsy and cataplexy
0.644 0.356 0.000
G47.2 Disorders of the sleep-wake schedule
0.644 0.356 0.000
T90.9 Sequelae of unspecified injury of head
0.643 0.357 0.000
S05.7 Avulsion of eye
0.643 0.357 0.000
S05.6 Penetrating wound of eyeball without foreign body
0.643 0.357 0.000
S05.5 Penetrating wound of eyeball with foreign body
0.643 0.357 0.000
S05.4 Penetrating wound of orbit with or without foreign body
0.643 0.357 0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.643 0.357 0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.643 0.357 0.000
S02.20 Fracture of nasal bones (closed)
0.643 0.357 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.643 0.357 0.000
S32 Fracture of lumbar spine and pelvis
0.642 0.358 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.642 0.358 0.000
R29.4 Clicking hip
0.641 0.359 0.000
R29.3 Abnormal posture
0.641 0.359 0.000
R29.2 Abnormal reflex
0.641 0.359 0.000
R29.1 Meningismus
0.641 0.359 0.000
R29.0 Tetany
0.641 0.359 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.640 0.360 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.640 0.360 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.640 0.360 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.640 0.360 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.640 0.360 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.640 0.360 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.640 0.360 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.640 0.360 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.640 0.360 0.000
S82.9 Fracture of lower leg, part unspecified
0.640 0.360 0.000
S82.7 Multiple fractures of lower leg
0.640 0.360 0.000
G30-G32 Other degenerative diseases of the nervous system
0.639 0.361 0.000
G44.0 Cluster headache syndrome
0.639 0.361 0.000
G82 Paraplegia and tetraplegia
0.639 0.361 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.638 0.362 0.000
T90.8 Sequelae of other specified injuries of head
0.638 0.362 0.000
T90.3 Sequelae of injury of cranial nerves
0.638 0.362 0.000
T90.0 Sequelae of superficial injury of head
0.638 0.362 0.000
G44.8 Other specified headache syndromes
0.638 0.362 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.637 0.363 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.637 0.363 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.637 0.363 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.637 0.363 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.637 0.363 0.000
I73.8 Other specified peripheral vascular diseases
0.636 0.363 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.636 0.363 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.636 0.364 0.000
G95.0 Syringomyelia and syringobulbia
0.636 0.364 0.000
T16 Foreign body in ear
0.636 0.364 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.635 0.365 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.635 0.365 0.000
I60.8 Other subarachnoid haemorrhage
0.635 0.365 0.000
S01.9 Open wound of head, part unspecified
0.635 0.365 0.000
S01.1 Open wound of eyelid and periocular area
0.635 0.365 0.000
Q21 Congenital malformations of cardiac septa
0.635 0.365 0.000
T98 Sequelae of other and unspecified effects of external causes
0.634 0.366 0.000
I77.8 Other specified disorders of arteries and arterioles
0.634 0.366 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.632 0.368 0.000
S60-S69 Injuries to the wrist and hand
0.631 0.369 0.000
K66 Other disorders of peritoneum
0.630 0.370 0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)
0.630 0.370 0.000
R27 Other lack of coordination
0.630 0.370 0.000
R45.2 Unhappiness
0.629 0.371 0.000
S82.86 Maisonneuve's fracture
0.629 0.371 0.000
S82.81 Fractures of other parts of lower leg (open)
0.629 0.371 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.629 0.371 0.000
R41.3 Other amnesia
0.628 0.372 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.627 0.373 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.627 0.373 0.000
I15.1 Hypertension secondary to other renal disorders
0.627 0.373 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.627 0.373 0.000
K37 Unspecified appendicitis
0.626 0.374 0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs
0.625 0.375 0.000
T91.4 Sequelae of injury of intrathoracic organs
0.625 0.375 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.625 0.375 0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk
0.625 0.375 0.000
S06.31 Focal brain injury (with open intracranial wound)
0.625 0.375 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.623 0.377 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.621 0.379 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.619 0.381 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.618 0.382 0.000
G95.8 Other specified diseases of spinal cord
0.618 0.382 0.000
I67.8 Other specified cerebrovascular diseases
0.618 0.382 0.000
I15.9 Seconday hypertension, unspecified
0.618 0.382 0.000
T93.2 Sequelae of other fractures of lower limb
0.618 0.382 0.000
S67 Crushing injury of wrist and hand
0.617 0.383 0.000
G62 Other polyneuropathies
0.616 0.384 0.000
K76 Other diseases of liver
0.616 0.384 0.000
M65-M68 Disorders of synovium and tendon
0.616 0.384 0.000
G06.2 Extradural and subdural abscess, unspecified
0.614 0.385 0.000
S42.30 Fracture of shaft of humerus (closed)
0.613 0.387 0.000
S82.21 Fracture of shaft of tibia (open)
0.613 0.387 0.000
G25.3 Myoclonus
0.613 0.387 0.000
G60 Hereditary and idiopathic neuropathy
0.611 0.389 0.000
R44.1 Visual hallucinations
0.610 0.389 0.000
F80-F89 Disorders of psychological development
0.610 0.390 0.000
F50 Eating disorders
0.609 0.391 0.000
G25.0 Essential tremor
0.608 0.392 0.000
K86.8 Other specified diseases of pancreas
0.608 0.392 0.000
K82.2 Perforation of gallbladder
0.608 0.392 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.608 0.392 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.608 0.392 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.607 0.392 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.606 0.394 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.606 0.394 0.000
Q23.4 Hypoplastic left heart syndrome
0.606 0.394 0.000
Q23.3 Congenital mitral insufficiency
0.606 0.394 0.000
Q23.2 Congenital mitral stenosis
0.606 0.394 0.000
Q23.0 Congenital stenosis of aortic valve
0.606 0.394 0.000
F23 Acute and transient psychotic disorders
0.605 0.395 0.000
R41.1 Anterograde amnesia
0.604 0.396 0.000
R47 Speech disturbances, not elsewhere classified
0.604 0.396 0.000
T63 Toxic effect of contact with venomous animals
0.604 0.396 0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)
0.603 0.397 0.000
K86.2 Cyst of pancreas
0.603 0.397 0.000
K81.8 Other cholecystitis
0.603 0.397 0.000
S89 Other and unspecified injuries of lower leg
0.602 0.398 0.000
I63.8 Other cerebral infarction
0.601 0.399 0.000
M54.19 Radiculopathy (Site unspecified)
0.601 0.399 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.600 0.400 0.000
R26 Abnormalities of gait and mobility
0.600 0.400 0.000
S01.2 Open wound of nose
0.600 0.400 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.599 0.401 0.000
G92 Toxic encephalopathy
0.599 0.401 0.000
Chapter VIII Diseases of the ear and mastoid process
0.597 0.403 0.000
T31 Burns classified according to extent of body surface involved
0.596 0.404 0.000
S41 Open wound of shoulder and upper arm
0.595 0.405 0.000
K74.6 Other and unspecified cirrhosis of liver
0.595 0.405 0.000
T65 Toxic effect of other and unspecified substances
0.595 0.405 0.000
T62 Toxic effect of other noxious substances eaten as food
0.595 0.405 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.595 0.405 0.000
T60 Toxic effect of pesticides
0.595 0.405 0.000
T57 Toxic effect of other inorganic substances
0.595 0.405 0.000
T56 Toxic effect of metals
0.595 0.405 0.000
T54 Toxic effect of corrosive substances
0.595 0.405 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.595 0.405 0.000
T52 Toxic effect of organic solvents
0.595 0.405 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.595 0.405 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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