TreeWAS – Variant ID: rs13431384

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.992	0.008
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.992	0.008
Chapter II Neoplasms	0.989	0.011
C15-C26 Malignant neoplasms of digestive organs	0.985	0.015
D37-D48 Neoplasms of uncertain or unknown behaviour	0.984	0.016
C79 Secondary malignant neoplasm of other sites	0.984	0.016
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.980	0.020
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.971	0.029
D37.5 Rectum	0.967	0.033
I60-I69 Cerebrovascular diseases	0.966	0.034
I63 Cerebral infarction	0.965	0.035
C16 Malignant neoplasm of stomach	0.965	0.035
I69 Sequelae of cerebrovascular disease	0.964	0.036
I63.9 Cerebral infarction, unspecified	0.960	0.040
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.956	0.044
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.955	0.045
T36-T50 Poisoning by drugs, medicaments and biological substances	0.952	0.048
S10-S19 Injuries to the neck	0.952	0.048
I67 Other cerebrovascular diseases	0.950	0.050
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.941	0.059
C78.7 Secondary malignant neoplasm of liver	0.941	0.059
T79-T79 Certain early complications of trauma	0.935	0.065
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.933	0.067
C77.2 Intra-abdominal lymph nodes	0.929	0.071
C20 Malignant neoplasm of rectum	0.927	0.073
C15 Malignant neoplasm of oesophagus	0.919	0.081
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.918	0.082
I67.9 Cerebrovascular disease, unspecified	0.918	0.082
S50-S59 Injuries to the elbow and forearm	0.910	0.090
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.908	0.092
S90-S99 Injuries to the ankle and foot	0.905	0.095
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.905	0.095
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.904	0.096
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.903	0.097
I67.8 Other specified cerebrovascular diseases	0.903	0.097
D37.7 Other digestive organs	0.898	0.102
S70-S79 Injuries to the hip and thigh	0.898	0.102
T79 Certain early complications of trauma, not elsewhere classified	0.895	0.105
C51-C58 Malignant neoplasms of female genital organs	0.895	0.105
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.891	0.109
I69.3 Sequelae of cerebral infarction	0.889	0.111
S32 Fracture of lumbar spine and pelvis	0.888	0.112
C78.0 Secondary malignant neoplasm of lung	0.887	0.113
I69.1 Sequelae of intracerebral haemorrhage	0.882	0.118
T20-T25 Burns and corrosions of external body surface, specified by site	0.877	0.123
T93 Sequelae of injuries of lower limb	0.876	0.124
C16.0 Cardia	0.874	0.126
S80-S89 Injuries to the knee and lower leg	0.864	0.136
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.855	0.145
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.855	0.145
S20-S29 Injuries to the thorax	0.852	0.148
I65.2 Occlusion and stenosis of carotid artery	0.851	0.149
D00-D09 In situ neoplasms	0.851	0.149
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.850	0.150
S30 Superficial injury of abdomen, lower back and pelvis	0.841	0.159
C79.6 Secondary malignant neoplasm of ovary	0.838	0.162
C16.9 Stomach, unspecified	0.837	0.163
T09 Other injuries of spine and trunk, level unspecified	0.836	0.164
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.834	0.166
C15.9 Oesophagus, unspecified	0.833	0.167
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.833	0.167
C53 Malignant neoplasm of cervix uteri	0.832	0.167
D37.4 Colon	0.829	0.171
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.825	0.175
T79.3 Post-traumatic wound infection, not elsewhere classified	0.820	0.180
T93.8 Sequelae of other specified injuries of lower limb	0.816	0.184
C16.1 Fundus of stomach	0.815	0.185
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.813	0.187
S90 Superficial injury of ankle and foot	0.812	0.188
C79.7 Secondary malignant neoplasm of adrenal gland	0.804	0.196
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.803	0.197
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.800	0.200
S10 Superficial injury of neck	0.798	0.202
S70 Superficial injury of hip and thigh	0.796	0.204
C76 Malignant neoplasm of other and ill-defined sites	0.794	0.206
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.793	0.207
I69.0 Sequelae of subarachnoid haemorrhage	0.793	0.207
T51 Toxic effect of alcohol	0.790	0.210
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.788	0.212
C07 Malignant neoplasm of parotid gland	0.788	0.212
T94 Sequelae of injuries involving multiple and unspecified body regions	0.787	0.213
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.783	0.217
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.782	0.218
C77.8 Lymph nodes of multiple regions	0.782	0.218
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.781	0.219
D46 Myelodysplastic syndromes	0.780	0.220
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.778	0.222
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.778	0.222
T79.5 Traumatic anuria	0.777	0.223
C53.9 Cervix uteri, unspecified	0.776	0.224
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.775	0.225
S32.0 Fracture of lumbar vertebra	0.773	0.227
C16.6 Greater curvature of stomach, unspecified	0.766	0.234
S51 Open wound of forearm	0.760	0.240
T92 Sequelae of injuries of upper limb	0.759	0.241
T56 Toxic effect of metals	0.759	0.241
S36 Injury of intra-abdominal organs	0.756	0.244
C23 Malignant neoplasm of gallbladder	0.753	0.247
S13.4 Sprain and strain of cervical spine	0.752	0.248
T23 Burn and corrosion of wrist and hand	0.751	0.249
T50.9 Other and unspecified drugs, medicaments and biological substances	0.749	0.251
T79.6 Traumatic ischaemia of muscle	0.748	0.252
S56 Injury of muscle and tendon at forearm level	0.747	0.253
S31 Open wound of abdomen, lower back and pelvis	0.746	0.254
C16.2 Body of stomach	0.746	0.254
D47.3 Essential (haemorrhagic) thrombocythaemia	0.745	0.255
S20 Superficial injury of thorax	0.744	0.256
C56 Malignant neoplasm of ovary	0.742	0.258
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.741	0.258
T51.0 Ethanol	0.741	0.259
C50-C50 Malignant neoplasm of breast	0.738	0.262
T90 Sequelae of injuries of head	0.737	0.263
S12 Fracture of neck	0.735	0.265
D06 Carcinoma in situ of cervix uteri	0.732	0.268
C25 Malignant neoplasm of pancreas	0.730	0.270
S14 Injury of nerves and spinal cord at neck level	0.728	0.272
S11 Open wound of neck	0.727	0.272
C77.4 Inguinal and lower limb lymph nodes	0.727	0.273
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.727	0.273
C21 Malignant neoplasm of anus and anal canal	0.725	0.274
S72 Fracture of femur	0.725	0.275
C79.2 Secondary malignant neoplasm of skin	0.725	0.275
C00 Malignant neoplasm of lip	0.725	0.275
D37.2 Small intestine	0.723	0.277
T36 Poisoning by systemic antibiotics	0.721	0.279
I65.0 Occlusion and stenosis of vertebral artery	0.721	0.279
S21 Open wound of thorax	0.718	0.282
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.717	0.283
T93.1 Sequelae of fracture of femur	0.713	0.287
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.713	0.287
C15.3 Upper third of oesophagus	0.713	0.287
S83.2 Tear of meniscus, current	0.713	0.287
S32.5 Fracture of pubis	0.712	0.288
S90.8 Other superficial injuries of ankle and foot	0.711	0.289
T33-T35 Frostbite	0.711	0.289
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.289
S30.2 Contusion of external genital organs	0.710	0.290
C40-C41 Malignant neoplasms of bone and articular cartilage	0.709	0.291
S32.7 Multiple fractures of lumbar spine and pelvis	0.709	0.291
S37 Injury of urinary and pelvic organs	0.708	0.291
S52 Fracture of forearm	0.707	0.293
C06 Malignant neoplasm of other and unspecified parts of mouth	0.706	0.294
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.706	0.294
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.706	0.294
I61 Intracerebral haemorrhage	0.705	0.295
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.705	0.295
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.705	0.295
C22.9 Liver, unspecified	0.705	0.295
C15.4 Middle third of oesophagus	0.703	0.297
D37.3 Appendix	0.703	0.297
C15.5 Lower third of oesophagus	0.701	0.299
T98 Sequelae of other and unspecified effects of external causes	0.701	0.299
T13 Other injuries of lower limb, level unspecified	0.700	0.299
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.700	0.300
S19 Other and unspecified injuries of neck	0.700	0.300
T00-T07 Injuries involving multiple body regions	0.699	0.301
T09.3 Injury of spinal cord, level unspecified	0.699	0.301
S50 Superficial injury of forearm	0.699	0.301
C04 Malignant neoplasm of floor of mouth	0.698	0.302
T91 Sequelae of injuries of neck and trunk	0.697	0.303
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.696	0.304
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.696	0.304
C78.1 Secondary malignant neoplasm of mediastinum	0.695	0.305
S90.3 Contusion of other and unspecified parts of foot	0.695	0.305
S13.1 Dislocation of cervical vertebra	0.694	0.306
I68 Cerebrovascular disorders in diseases classified elsewhere	0.692	0.307
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.692	0.307
T09.0 Superficial injury of trunk, level unspecified	0.692	0.308
D37.9 Digestive organ, unspecified	0.692	0.308
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.692	0.308
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.692	0.308
S32.00 Fracture of lumbar vertebra (closed)	0.692	0.308
C16.8 Overlapping lesion of stomach	0.691	0.308
C16.4 Pylorus	0.691	0.308
C16.3 Pyloric antrum	0.691	0.308
S70.1 Contusion of thigh	0.691	0.309
D39.1 Ovary	0.691	0.309
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.691	0.309
T25 Burn and corrosion of ankle and foot	0.691	0.309
T46 Poisoning by agents primarily affecting the cardiovascular system	0.690	0.310
C26 Malignant neoplasm of other and ill-defined digestive organs	0.690	0.310
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.690	0.310
C22.0 Liver cell carcinoma	0.690	0.310
S10.9 Superficial injury of neck, part unspecified	0.689	0.311
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.688	0.312
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.688	0.312
S30.1 Contusion of abdominal wall	0.687	0.313
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.686	0.314
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.685	0.314
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.685	0.314
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.685	0.314
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.685	0.314
D37.0 Lip, oral cavity and pharynx	0.685	0.315
T95 Sequelae of burns, corrosions and frostbite	0.685	0.315
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.685	0.315
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.685	0.315
S86 Injury of muscle and tendon at lower leg level	0.684	0.316
T43.5 Other and unspecified antipsychotics and neuroleptics	0.683	0.317
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.683	0.317
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.683	0.317
T41 Poisoning by anaesthetics and therapeutic gases	0.683	0.317
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.683	0.317
S17 Crushing injury of neck	0.682	0.318
S15 Injury of blood vessels at neck level	0.682	0.318
S18 Traumatic amputation at neck level	0.682	0.318
S16 Injury of muscle and tendon at neck level	0.682	0.318
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.682	0.318
I67.7 Cerebral arteritis, not elsewhere classified	0.681	0.319
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.681	0.319
I67.5 Moyamoya disease	0.681	0.319
I67.4 Hypertensive encephalopathy	0.681	0.319
I67.3 Progressive vascular leukoencephalopathy	0.681	0.319
T93.0 Sequelae of open wound of lower limb	0.681	0.319
S91 Open wound of ankle and foot	0.680	0.320
S32.3 Fracture of ilium	0.679	0.321
C01 Malignant neoplasm of base of tongue	0.679	0.321
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.678	0.322
C17 Malignant neoplasm of small intestine	0.676	0.324
C78.2 Secondary malignant neoplasm of pleura	0.675	0.325
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.673	0.327
S32.4 Fracture of acetabulum	0.671	0.329
T45.1 Antineoplastic and immunosuppressive drugs	0.670	0.330
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.669	0.331
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.668	0.332
S92 Fracture of foot, except ankle	0.667	0.333
T94.1 Sequelae of injuries, not specified by body region	0.667	0.333
S30.0 Contusion of lower back and pelvis	0.666	0.334
T56.8 Other metals	0.664	0.336
I63.8 Other cerebral infarction	0.663	0.336
C16.5 Lesser curvature of stomach, unspecified	0.663	0.337
S80 Superficial injury of lower leg	0.663	0.337
S59 Other and unspecified injuries of forearm	0.663	0.337
T23.2 Burn of second degree of wrist and hand	0.661	0.339
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.660	0.340
C15.8 Overlapping lesion of oesophagus	0.659	0.341
C15.2 Abdominal part of oesophagus	0.659	0.341
C15.1 Thoracic part of oesophagus	0.659	0.341
C15.0 Cervical part of oesophagus	0.659	0.341
C79.8 Secondary malignant neoplasm of other specified sites	0.657	0.343
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.657	0.343
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.656	0.343
S96 Injury of muscle and tendon at ankle and foot level	0.656	0.343
C77.9 Lymph node, unspecified	0.656	0.344
S58 Traumatic amputation of forearm	0.652	0.348
S57 Crushing injury of forearm	0.652	0.348
S55 Injury of blood vessels at forearm level	0.652	0.348
S54 Injury of nerves at forearm level	0.652	0.348
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.652	0.348
S99 Other and unspecified injuries of ankle and foot	0.652	0.348
C76.1 Thorax	0.651	0.348
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.651	0.349
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.651	0.349
I65.8 Occlusion and stenosis of other precerebral artery	0.651	0.349
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.651	0.349
I65.1 Occlusion and stenosis of basilar artery	0.651	0.349
C77.3 Axillary and upper limb lymph nodes	0.650	0.350
S98 Traumatic amputation of ankle and foot	0.649	0.351
S97 Crushing injury of ankle and foot	0.649	0.351
S95 Injury of blood vessels at ankle and foot level	0.649	0.351
S94 Injury of nerves at ankle and foot level	0.649	0.351
D37.1 Stomach	0.649	0.351
C13 Malignant neoplasm of hypopharynx	0.648	0.351
C11 Malignant neoplasm of nasopharynx	0.648	0.351
C08 Malignant neoplasm of other and unspecified major salivary glands	0.648	0.351
C05 Malignant neoplasm of palate	0.648	0.351
C03 Malignant neoplasm of gum	0.648	0.351
C12 Malignant neoplasm of pyriform sinus	0.648	0.351
T11 Other injuries of upper limb, level unspecified	0.647	0.352
T12.X1 Fracture of lower limb, level unspecified (open)	0.647	0.352
T12.X0 Fracture of lower limb, level unspecified (closed)	0.647	0.352
T12 Fracture of lower limb, level unspecified	0.647	0.352
T10.X1 Fracture of upper limb, level unspecified (open)	0.647	0.352
T10.X0 Fracture of upper limb, level unspecified (closed)	0.647	0.352
T10 Fracture of upper limb, level unspecified	0.647	0.352
T08.X1 Fracture of spine, level unspecified (open)	0.647	0.352
T08.X0 Fracture of spine, level unspecified (closed)	0.647	0.352
T08 Fracture of spine, level unspecified	0.647	0.352
C53.0 Endocervix	0.647	0.353
D06.9 Cervix, unspecified	0.646	0.354
D09 Carcinoma in situ of other and unspecified sites	0.644	0.356
I67.0 Dissection of cerebral arteries, nonruptured	0.644	0.356
S78 Traumatic amputation of hip and thigh	0.644	0.356
S77 Crushing injury of hip and thigh	0.644	0.356
S76 Injury of muscle and tendon at hip and thigh level	0.644	0.356
S75 Injury of blood vessels at hip and thigh level	0.644	0.356
S74 Injury of nerves at hip and thigh level	0.644	0.356
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.643	0.357
T66-T78 Other and unspecified effects of external causes	0.642	0.358
T79.9 Unspecified early complication of trauma	0.642	0.358
T79.4 Traumatic shock	0.642	0.358
T79.2 Traumatic secondary and recurrent haemorrhage	0.642	0.358
T79.1 Fat embolism (traumatic)	0.642	0.358
T79.0 Air embolism (traumatic)	0.642	0.358
C57 Malignant neoplasm of other and unspecified female genital organs	0.642	0.358
C58 Malignant neoplasm of placenta	0.642	0.358
C52 Malignant neoplasm of vagina	0.642	0.358
T65 Toxic effect of other and unspecified substances	0.639	0.361
T62 Toxic effect of other noxious substances eaten as food	0.639	0.361
T61 Toxic effect of noxious substances eaten as seafood	0.639	0.361
T60 Toxic effect of pesticides	0.639	0.361
T57 Toxic effect of other inorganic substances	0.639	0.361
T54 Toxic effect of corrosive substances	0.639	0.361
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.639	0.361
T52 Toxic effect of organic solvents	0.639	0.361
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.639	0.361
T55 Toxic effect of soaps and detergents	0.639	0.361
C51 Malignant neoplasm of vulva	0.639	0.361
T92.8 Sequelae of other specified injuries of upper limb	0.639	0.361
D37.6 Liver, gallbladder and bile ducts	0.637	0.363
S82 Fracture of lower leg, including ankle	0.637	0.363
S32.2 Fracture of coccyx	0.636	0.363
S20.8 Superficial injuries of other and unspecified parts of thorax	0.636	0.364
S29 Other and unspecified injuries of thorax	0.636	0.364
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.635	0.364
S71 Open wound of hip and thigh	0.635	0.365
D48.0 Bone and articular cartilage	0.635	0.365
I67.2 Cerebral atherosclerosis	0.634	0.366
T43.3 Phenothiazine antipsychotics and neuroleptics	0.633	0.367
D46.9 Myelodysplastic syndrome, unspecified	0.633	0.367
T63 Toxic effect of contact with venomous animals	0.632	0.368
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.632	0.368
C71 Malignant neoplasm of brain	0.631	0.369
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.630	0.370
T21 Burn and corrosion of trunk	0.629	0.371
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.629	0.371
S70.9 Superficial injury of hip and thigh, unspecified	0.628	0.372
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.628	0.372
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.628	0.372
T93.4 Sequelae of injury of nerve of lower limb	0.628	0.372
T59 Toxic effect of other gases, fumes and vapours	0.627	0.373
D04 Carcinoma in situ of skin	0.625	0.375
C02 Malignant neoplasm of other and unspecified parts of tongue	0.623	0.377
S21.9 Open wound of thorax, part unspecified	0.623	0.377
C10 Malignant neoplasm of oropharynx	0.622	0.378
T93.9 Sequelae of unspecified injury of lower limb	0.622	0.378
S88 Traumatic amputation of lower leg	0.619	0.380
S87 Crushing injury of lower leg	0.619	0.380
S85 Injury of blood vessels at lower leg level	0.619	0.380
S84 Injury of nerves at lower leg level	0.619	0.380
S72.1 Pertrochanteric fracture	0.619	0.380
C25.9 Pancreas, unspecified	0.616	0.384
S80.0 Contusion of knee	0.616	0.384
S51.9 Open wound of forearm, part unspecified	0.616	0.384
D03 Melanoma in situ	0.615	0.385
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.613	0.387
T42.5 Mixed antiepileptics, not elsewhere classified	0.613	0.387
T42.3 Barbiturates	0.613	0.387
T42.2 Succinimides and oxazolidinediones	0.613	0.387
T42.0 Hydantoin derivatives	0.613	0.387
S36.8 Injury of other intra-abdominal organs	0.613	0.387
S13.5 Sprain and strain of thyroid region	0.613	0.387
S13.3 Multiple dislocations of neck	0.613	0.387
S13.2 Dislocation of other and unspecified parts of neck	0.613	0.387
S13.0 Traumatic rupture of cervical intervertebral disk	0.613	0.387
D47.1 Chronic myeloproliferative disease	0.612	0.387
D00.1 Oesophagus	0.612	0.388
C22.1 Intrahepatic bile duct carcinoma	0.612	0.388
S51.0 Open wound of elbow	0.612	0.388
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.611	0.389
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.611	0.389
S26 Injury of heart	0.611	0.389
S25 Injury of blood vessels of thorax	0.611	0.389
S24 Injury of nerves and spinal cord at thorax level	0.611	0.389
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.611	0.389
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.610	0.390
D01 Carcinoma in situ of other and unspecified digestive organs	0.610	0.390
S79 Other and unspecified injuries of hip and thigh	0.610	0.390
C22.7 Other specified carcinomas of liver	0.610	0.390
C22.4 Other sarcomas of liver	0.610	0.390
C22.3 Angiosarcoma of liver	0.610	0.390
C22.2 Hepatoblastoma	0.610	0.390
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.608	0.392
S52.5 Fracture of lower end of radius	0.605	0.395
T79.8 Other early complications of trauma	0.604	0.395
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.603	0.397
T45.0 Antiallergic and antiemetic drugs	0.603	0.397
T43.2 Other and unspecified antidepressants	0.603	0.397
S82.6 Fracture of lateral malleolus	0.602	0.398
T42.1 Iminostilbenes	0.600	0.400
T09.9 Unspecified injury of trunk, level unspecified	0.599	0.400
T09.8 Other specified injuries of trunk, level unspecified	0.599	0.400
T09.6 Traumatic amputation of trunk, level unspecified	0.599	0.400
T09.5 Injury of unspecified muscle and tendon of trunk	0.599	0.400
T09.4 Injury of unspecified nerve, spinal nerve root and plexus of trunk	0.599	0.400
T09.1 Open wound of trunk, level unspecified	0.599	0.400
T14 Injury of unspecified body region	0.599	0.401
T50.8 Diagnostic agents	0.598	0.402
T50.7 Analeptics and opioid receptor antagonists	0.598	0.402
T50.6 Antidotes and chelating agents, not elsewhere classified	0.598	0.402
T50.5 Appetite depressants	0.598	0.402
T50.4 Drugs affecting uric acid metabolism	0.598	0.402
T50.3 Electrolytic, caloric and water-balance agents	0.598	0.402
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.598	0.402
T50.1 Loop [high-ceiling] diuretics	0.598	0.402
T50.0 Mineralocorticoids and their antagonists	0.598	0.402
C53.8 Overlapping lesion of cervix uteri	0.597	0.403
C53.1 Exocervix	0.597	0.403
T20 Burn and corrosion of head and neck	0.596	0.403
T90.9 Sequelae of unspecified injury of head	0.596	0.404
C00.9 Lip, unspecified	0.596	0.404
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.595	0.405
T90.5 Sequelae of intracranial injury	0.592	0.408
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.591	0.409
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.591	0.409
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.591	0.409
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.591	0.409
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.590	0.410
D48.1 Connective and other soft tissue	0.589	0.411
D02 Carcinoma in situ of middle ear and respiratory system	0.588	0.412
S70.0 Contusion of hip	0.587	0.413
S32.50 Fracture of pubis (closed)	0.587	0.413
C25.3 Pancreatic duct	0.587	0.413
D39.9 Female genital organ, unspecified	0.583	0.417
D39.7 Other female genital organs	0.583	0.417
D39.2 Placenta	0.583	0.417
D39.0 Uterus	0.583	0.417
S90.7 Multiple superficial injuries of ankle and foot	0.582	0.418
S90.2 Contusion of toe(s) with damage to nail	0.582	0.418
S90.1 Contusion of toe(s) without damage to nail	0.582	0.418
S90.0 Contusion of ankle	0.582	0.418
T45.5 Anticoagulants	0.582	0.418
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.580	0.420
T92.2 Sequelae of fracture at wrist and hand level	0.580	0.420
T79.7 Traumatic subcutaneous emphysema	0.580	0.420
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.578	0.422
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.577	0.423
S31.0 Open wound of lower back and pelvis	0.577	0.423
S82.60 Fracture of lateral malleolus (closed)	0.577	0.423
T58 Toxic effect of carbon monoxide	0.576	0.424
S92.0 Fracture of calcaneus	0.576	0.424
D48.5 Skin	0.576	0.424
C55 Malignant neoplasm of uterus, part unspecified	0.575	0.425
T45.9 Primarily systemic and haematological agent, unspecified	0.573	0.426
T45.8 Other primarily systemic and haematological agents	0.573	0.426
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.573	0.426
T45.6 Fibrinolysis-affecting drugs	0.573	0.426
T45.4 Iron and its compounds	0.573	0.426
T45.3 Enzymes, not elsewhere classified	0.573	0.426
T45.2 Vitamins, not elsewhere classified	0.573	0.426
S10.8 Superficial injury of other parts of neck	0.572	0.427
S10.7 Multiple superficial injuries of neck	0.572	0.427
S10.1 Other and unspecified superficial injuries of throat	0.572	0.427
S10.0 Contusion of throat	0.572	0.427
T92.9 Sequelae of unspecified injury of upper limb	0.572	0.428
T90.4 Sequelae of injury of eye and orbit	0.571	0.429
S20.2 Contusion of thorax	0.571	0.429
S70.8 Other superficial injuries of hip and thigh	0.571	0.429
S70.7 Multiple superficial injuries of hip and thigh	0.571	0.429
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.570	0.430
C76.8 Overlapping lesion of other and ill-defined sites	0.569	0.431
C76.7 Other ill-defined sites	0.569	0.431
C76.5 Lower limb	0.569	0.431
C76.4 Upper limb	0.569	0.431
C76.3 Pelvis	0.569	0.431
C76.2 Abdomen	0.569	0.431
C76.0 Head, face and neck	0.569	0.431
S50.8 Other superficial injuries of forearm	0.569	0.431
D47.4 Osteomyelofibrosis	0.568	0.432
S14.1 Other and unspecified injuries of cervical spinal cord	0.568	0.432
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.567	0.433
D00.0 Lip, oral cavity and pharynx	0.567	0.433
D48.6 Breast	0.567	0.433
C78.4 Secondary malignant neoplasm of small intestine	0.567	0.433
S11.9 Open wound of neck, part unspecified	0.567	0.433
S12.7 Multiple fractures of cervical spine	0.567	0.433
T51.8 Other alcohols	0.566	0.433
T51.3 Fusel oil	0.566	0.433
T51.2 2-Propanol	0.566	0.433
T51.1 Methanol	0.566	0.433
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.565	0.435
D48.4 Peritoneum	0.565	0.435
D48.3 Retroperitoneum	0.565	0.435
D48.2 Peripheral nerves and autonomic nervous system	0.565	0.435
C77.5 Intrapelvic lymph nodes	0.564	0.435
T94.0 Sequelae of injuries involving multiple body regions	0.564	0.435
C06.9 Mouth, unspecified	0.564	0.436
C14.0 Pharynx, unspecified	0.562	0.438
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.561	0.438
T43.9 Psychotropic drug, unspecified	0.560	0.440
T43.8 Other psychotropic drugs, not elsewhere classified	0.560	0.440
T43.6 Psychostimulants with abuse potential	0.560	0.440
T43.4 Butyrophenone and thioxanthene neuroleptics	0.560	0.440
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.560	0.440
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.559	0.440
T92.0 Sequelae of open wound of upper limb	0.559	0.441
D46.7 Other myelodysplastic syndromes	0.559	0.441
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.559	0.441
D46.5 Refractory anaemia with multi-lineage dysplasia	0.559	0.441
D46.4 Refractory anaemia, unspecified	0.559	0.441
D46.3 Refractory anaemia with excess of blasts with transformation	0.559	0.441
D46.2 Refractory anaemia with excess of blasts	0.559	0.441
D46.1 Refractory anaemia with sideroblasts	0.559	0.441
D46.0 Refractory anaemia without sideroblasts, so stated	0.559	0.441
S20.3 Other superficial injuries of front wall of thorax	0.559	0.441
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.558	0.442
S83.7 Injury to multiple structures of knee	0.558	0.442
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.558	0.442
S83.3 Tear of articular cartilage of knee, current	0.558	0.442
S83.1 Dislocation of knee	0.558	0.442
S83.0 Dislocation of patella	0.558	0.442

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations