TreeWAS – Variant ID: rs137931178

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	0.595	0.405	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.591	0.409	0.000
M70-M79 Other soft tissue disorders	0.583	0.417	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.578	0.422	0.000
Chapter II Neoplasms	0.577	0.423	0.000
M75 Shoulder lesions	0.576	0.424	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.571	0.429	0.000
M75.1 Rotator cuff syndrome	0.557	0.443	0.000
D10-D36 Benign neoplasms	0.550	0.450	0.000
Chapter V Mental and behavioural disorders	0.548	0.452	0.000
Chapter XXI Factors influencing health status and contact with health services	0.546	0.454	0.000
E70-E90 Metabolic disorders	0.543	0.457	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.536	0.464	0.000
M75.4 Impingement syndrome of shoulder	0.534	0.466	0.000
Chapter VIII Diseases of the ear and mastoid process	0.527	0.473	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.523	0.477	0.000
D25 Leiomyoma of uterus	0.508	0.492	0.000
F41 Other anxiety disorders	0.499	0.501	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.496	0.504	0.000
O48 Prolonged pregnancy	0.493	0.507	0.000
E86 Volume depletion	0.493	0.507	0.000
D00-D09 In situ neoplasms	0.488	0.512	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.486	0.514	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.486	0.514	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.482	0.518	0.000
O80-O84 Delivery	0.481	0.519	0.000
D25.9 Leiomyoma of uterus, unspecified	0.479	0.521	0.000
H65-H75 Diseases of middle ear and mastoid	0.479	0.521	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.478	0.522	0.000
E78.0 Pure hypercholesterolaemia	0.476	0.524	0.000
M05-M14 Inflammatory polyarthropathies	0.473	0.527	0.000
E00-E07 Disorders of thyroid gland	0.472	0.528	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.472	0.528	0.000
C15-C26 Malignant neoplasms of digestive organs	0.470	0.530	0.000
F41.2 Mixed anxiety and depressive disorder	0.469	0.531	0.000
E20-E35 Disorders of other endocrine glands	0.468	0.532	0.000
M50-M54 Other dorsopathies	0.465	0.535	0.000
M45-M49 Spondylopathies	0.461	0.538	0.000
D17 Benign lipomatous neoplasm	0.459	0.541	0.000
M40-M43 Deforming dorsopathies	0.452	0.548	0.000
M86-M90 Other osteopathies	0.451	0.549	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.450	0.550	0.000
Chapter VII Diseases of the eye and adnexa	0.449	0.551	0.000
D18 Haemangioma and lymphangioma, any site	0.449	0.551	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.446	0.554	0.000
M15-M19 Arthrosis	0.443	0.557	0.000
E83 Disorders of mineral metabolism	0.443	0.557	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.439	0.561	0.000
O36 Maternal care for other known or suspected foetal problems	0.438	0.562	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.437	0.563	0.000
Chapter I Certain infectious and parasitic diseases	0.430	0.570	0.000
M65-M68 Disorders of synovium and tendon	0.429	0.571	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.427	0.573	0.000
Chapter XXII Codes for special purposes	0.427	0.573	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.427	0.573	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.427	0.573	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.424	0.576	0.000
M91-M94 Chondropathies	0.424	0.576	0.000
M60-M63 Disorders of muscles	0.424	0.576	0.000
M00-M03 Infectious arthropathies	0.424	0.576	0.000
O00-O08 Pregnancy with abortive outcome	0.424	0.576	0.000
O60-O75 Complications of labour and delivery	0.423	0.577	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.423	0.577	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.421	0.579	0.000
M77 Other enthesopathies	0.418	0.582	0.000
M76 Enthesopathies of lower limb, excluding foot	0.418	0.582	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.418	0.582	0.000
M71 Other bursopathies	0.418	0.582	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.418	0.582	0.000
O85-O92 Complications predominantly related to the puerperium	0.414	0.585	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.414	0.586	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.414	0.586	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.414	0.586	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.414	0.586	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.414	0.586	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.414	0.586	0.000
O16 Unspecified maternal hypertension	0.414	0.586	0.000
M75.8 Other shoulder lesions	0.413	0.587	0.000
M75.9 Shoulder lesion, unspecified	0.413	0.587	0.000
M75.5 Bursitis of shoulder	0.413	0.587	0.000
M75.3 Calcific tendinitis of shoulder	0.413	0.587	0.000
M75.2 Bicipital tendinitis	0.413	0.587	0.000
O80 Single spontaneous delivery	0.411	0.589	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.411	0.589	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.410	0.589	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.410	0.590	0.000
M80-M85 Disorders of bone density and structure	0.410	0.590	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.410	0.590	0.000
E40-E46 Malnutrition	0.409	0.591	0.000
Chapter XIV Diseases of the genitourinary system	0.409	0.591	0.000
F43 Reaction to severe stress, and adjustment disorders	0.408	0.592	0.000
M79.6 Pain in limb	0.408	0.592	0.000
Z36 Antenatal screening	0.406	0.593	0.000
Z34 Supervision of normal pregnancy	0.405	0.595	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.405	0.595	0.000
O47 False labour	0.405	0.595	0.000
E50-E64 Other nutritional deficiencies	0.404	0.596	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.404	0.596	0.000
D05 Carcinoma in situ of breast	0.403	0.597	0.000
M48 Other spondylopathies	0.402	0.598	0.000
M50 Cervical disk disorders	0.402	0.598	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.401	0.599	0.000
C50-C50 Malignant neoplasm of breast	0.401	0.599	0.000
D35.1 Parathyroid gland	0.401	0.599	0.000
E10-E14 Diabetes mellitus	0.401	0.599	0.000
H65 Nonsuppurative otitis media	0.401	0.599	0.000
C64-C68 Malignant neoplasms of urinary tract	0.399	0.601	0.000
C60-C63 Malignant neoplasms of male genital organs	0.398	0.602	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.398	0.602	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.395	0.605	0.000
D36 Benign neoplasm of other and unspecified sites	0.394	0.606	0.000
D32 Benign neoplasm of meninges	0.394	0.606	0.000
D31 Benign neoplasm of eye and adnexa	0.394	0.606	0.000
D30 Benign neoplasm of urinary organs	0.394	0.606	0.000
D29 Benign neoplasm of male genital organs	0.394	0.606	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.394	0.606	0.000
D26 Other benign neoplasms of uterus	0.394	0.606	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.394	0.606	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.394	0.606	0.000
D19 Benign neoplasm of mesothelial tissue	0.394	0.606	0.000
D16 Benign neoplasm of bone and articular cartilage	0.394	0.606	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.394	0.606	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.394	0.606	0.000
D11 Benign neoplasm of major salivary glands	0.394	0.606	0.000
D10 Benign neoplasm of mouth and pharynx	0.394	0.606	0.000
D34 Benign neoplasm of thyroid gland	0.394	0.606	0.000
F99-F99 Unspecified mental disorder	0.393	0.607	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.393	0.607	0.000
F80-F89 Disorders of psychological development	0.393	0.607	0.000
F70-F79 Mental retardation	0.393	0.607	0.000
F60-F69 Disorders of adult personality and behaviour	0.393	0.607	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.393	0.607	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.393	0.607	0.000
D25.0 Submucous leiomyoma of uterus	0.392	0.607	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.392	0.608	0.000
H90-H95 Other disorders of ear	0.391	0.609	0.000
D27 Benign neoplasm of ovary	0.390	0.610	0.000
E88 Other metabolic disorders	0.390	0.610	0.000
E85 Amyloidosis	0.390	0.610	0.000
E84 Cystic fibrosis	0.390	0.610	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.390	0.610	0.000
E79 Disorders of purine and pyrimidine metabolism	0.390	0.610	0.000
E77 Disorders of glycoprotein metabolism	0.390	0.610	0.000
E76 Disorders of glycosaminoglycan metabolism	0.390	0.610	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.390	0.610	0.000
E74 Other disorders of carbohydrate metabolism	0.390	0.610	0.000
E73 Lactose intolerance	0.390	0.610	0.000
E72 Other disorders of amino-acid metabolism	0.390	0.610	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.390	0.610	0.000
E70 Disorders of aromatic amino-acid metabolism	0.390	0.610	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.390	0.610	0.000
C51-C58 Malignant neoplasms of female genital organs	0.386	0.614	0.000
F40 Phobic anxiety disorders	0.385	0.614	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.386	0.614	0.000
D06 Carcinoma in situ of cervix uteri	0.385	0.615	0.000
H72 Perforation of tympanic membrane	0.385	0.615	0.000
M72 Fibroblastic disorders	0.385	0.615	0.000
Z37 Outcome of delivery	0.385	0.615	0.000
E03 Other hypothyroidism	0.384	0.616	0.000
O45 Premature separation of placenta [abruptio placentae]	0.384	0.616	0.000
O44 Placenta praevia	0.384	0.616	0.000
O43 Placental disorders	0.384	0.616	0.000
O42 Premature rupture of membranes	0.384	0.616	0.000
O41 Other disorders of amniotic fluid and membranes	0.384	0.616	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.384	0.616	0.000
O33 Maternal care for known or suspected disproportion	0.384	0.616	0.000
O31 Complications specific to multiple gestation	0.384	0.616	0.000
O30 Multiple gestation	0.384	0.616	0.000
O40 Polyhydramnios	0.384	0.616	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.383	0.617	0.000
C15 Malignant neoplasm of oesophagus	0.381	0.619	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.380	0.620	0.000
Z04 Examination and observation for other reasons	0.380	0.620	0.000
H73 Other disorders of tympanic membrane	0.379	0.621	0.000
H60-H62 Diseases of external ear	0.378	0.622	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.377	0.622	0.000
D24 Benign neoplasm of breast	0.377	0.623	0.000
D18.0 Haemangioma, any site	0.377	0.623	0.000
F48 Other neurotic disorders	0.375	0.625	0.000
F45 Somatoform disorders	0.375	0.625	0.000
F44 Dissociative [conversion] disorders	0.375	0.625	0.000
F42 Obsessive-compulsive disorder	0.375	0.625	0.000
Z02 Examination and encounter for administrative purposes	0.375	0.625	0.000
M75.0 Adhesive capsulitis of shoulder	0.374	0.626	0.000
C25 Malignant neoplasm of pancreas	0.372	0.628	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.371	0.628	0.000
N20-N23 Urolithiasis	0.371	0.629	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.371	0.629	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.371	0.629	0.000
Z03 Medical observation and evaluation for suspected diseases and conditions	0.370	0.630	0.000
D35.2 Pituitary gland	0.366	0.634	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.366	0.634	0.000
D25.2 Subserosal leiomyoma of uterus	0.365	0.635	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.365	0.635	0.000
H80-H83 Diseases of inner ear	0.364	0.636	0.000
M13 Other arthritis	0.362	0.638	0.000
A30-A49 Other bacterial diseases	0.362	0.638	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.361	0.639	0.000
Chapter X Diseases of the respiratory system	0.361	0.639	0.001
M10 Gout	0.361	0.639	0.000
H71 Cholesteatoma of middle ear	0.360	0.640	0.000
E83.5 Disorders of calcium metabolism	0.360	0.640	0.000
M48.0 Spinal stenosis	0.359	0.641	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.359	0.641	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.359	0.641	0.000
C34 Malignant neoplasm of bronchus and lung	0.359	0.641	0.000
F41.8 Other specified anxiety disorders	0.358	0.642	0.000
F41.3 Other mixed anxiety disorders	0.358	0.642	0.000
F41.1 Generalised anxiety disorder	0.358	0.642	0.000
O80.9 Single spontaneous delivery, unspecified	0.356	0.644	0.000
H43-H45 Disorders of vitreous body and globe	0.356	0.644	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.355	0.644	0.000
E78.8 Other disorders of lipoprotein metabolism	0.355	0.644	0.000
E78.6 Lipoprotein deficiency	0.355	0.644	0.000
E78.4 Other hyperlipidaemia	0.355	0.644	0.000
E78.3 Hyperchylomicronaemia	0.355	0.644	0.000
E78.2 Mixed hyperlipidaemia	0.355	0.644	0.000
E78.1 Pure hyperglyceridaemia	0.355	0.644	0.000
H53-H54 Visual disturbances and blindness	0.355	0.645	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.355	0.645	0.000
Chapter VI Diseases of the nervous system	0.354	0.646	0.000
E04 Other non-toxic goitre	0.353	0.647	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.353	0.647	0.000
D23 Other benign neoplasms of skin	0.353	0.647	0.000
M43 Other deforming dorsopathies	0.352	0.648	0.000
M06 Other rheumatoid arthritis	0.352	0.648	0.000
O36.5 Maternal care for poor foetal growth	0.352	0.648	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.351	0.649	0.000
M89 Other disorders of bone	0.351	0.649	0.000
C20 Malignant neoplasm of rectum	0.351	0.649	0.000
D09 Carcinoma in situ of other and unspecified sites	0.350	0.650	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.350	0.650	0.000
D04 Carcinoma in situ of skin	0.350	0.650	0.000
D03 Melanoma in situ	0.350	0.650	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.350	0.650	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.350	0.650	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.350	0.650	0.000
Z36.8 Other antenatal screening	0.349	0.650	0.000
F30-F39 Mood [affective] disorders	0.349	0.651	0.000
Z39 Postpartum care and examination	0.349	0.651	0.000
Z38 Liveborn infants according to place of birth	0.349	0.651	0.000
Z35 Supervision of high-risk pregnancy	0.349	0.651	0.000
Z32 Pregnancy examination and test	0.349	0.651	0.000
Z31 Procreative management	0.349	0.651	0.000
Z33 Pregnant state, incidental	0.349	0.651	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.349	0.651	0.000
Z10 Routine general health check-up of defined subpopulation	0.349	0.651	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.349	0.651	0.000
M16 Coxarthrosis [arthrosis of hip]	0.347	0.653	0.000
O15 Eclampsia	0.346	0.654	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.346	0.654	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.346	0.654	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.346	0.654	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.346	0.654	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.346	0.654	0.000
D22 Melanocytic naevi	0.345	0.654	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.345	0.655	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.345	0.655	0.000
O84 Multiple delivery	0.345	0.655	0.000
O83 Other assisted single delivery	0.345	0.655	0.000
O82 Single delivery by Caesarean section	0.345	0.655	0.000
O81 Single delivery by forceps and vacuum extractor	0.345	0.655	0.000
N20 Calculus of kidney and ureter	0.344	0.655	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.344	0.656	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.343	0.657	0.000
H74 Other disorders of middle ear and mastoid	0.343	0.657	0.000
H70 Mastoiditis and related conditions	0.343	0.657	0.000
H69 Other disorders of Eustachian tube	0.343	0.657	0.000
H68 Eustachian salpingitis and obstruction	0.343	0.657	0.000
H67 Otitis media in diseases classified elsewhere	0.343	0.657	0.000
H66 Suppurative and unspecified otitis media	0.343	0.657	0.000
M79.9 Soft tissue disorder, unspecified	0.342	0.657	0.000
M79.7 Fibromyalgia	0.342	0.657	0.000
M79.5 Residual foreign body in soft tissue	0.342	0.657	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.342	0.657	0.000
M79.3 Panniculitis, unspecified	0.342	0.657	0.000
M79.2 Neuralgia and neuritis, unspecified	0.342	0.657	0.000
M79.1 Myalgia	0.342	0.657	0.000
M79.0 Rheumatism, unspecified	0.342	0.657	0.000
Z40-Z54 Persons encountering health services for specific procedures and health care	0.341	0.659	0.000
M50.3 Other cervical disk degeneration	0.341	0.659	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.340	0.660	0.000
M14 Arthropathies in other diseases classified elsewhere	0.339	0.661	0.000
M12 Other specific arthropathies	0.339	0.661	0.000
M11 Other crystal arthropathies	0.339	0.661	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.339	0.661	0.000
M08 Juvenile arthritis	0.339	0.661	0.000
M07 Psoriatic and enteropathic arthropathies	0.339	0.661	0.000
M05 Seropositive rheumatoid arthritis	0.339	0.661	0.000
D45 Polycythaemia vera	0.339	0.661	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.339	0.661	0.000
J30-J39 Other diseases of upper respiratory tract	0.339	0.661	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.339	0.661	0.000
E07 Other disorders of thyroid	0.339	0.661	0.000
E06 Thyroiditis	0.339	0.661	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.339	0.661	0.000
E00 Congenital iodine-deficiency syndrome	0.339	0.661	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.339	0.661	0.000
C43 Malignant melanoma of skin	0.339	0.661	0.000
D35.9 Endocrine gland, unspecified	0.338	0.662	0.000
D35.8 Pluriglandular involvement	0.338	0.662	0.000
D35.7 Other specified endocrine glands	0.338	0.662	0.000
D35.6 Aortic body and other paraganglia	0.338	0.662	0.000
D35.5 Carotid body	0.338	0.662	0.000
D35.4 Pineal gland	0.338	0.662	0.000
D35.3 Craniopharyngeal duct	0.338	0.662	0.000
D35.0 Adrenal gland	0.338	0.662	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.338	0.662	0.000
O36.8 Maternal care for other specified foetal problems	0.338	0.662	0.000
C18 Malignant neoplasm of colon	0.337	0.663	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.337	0.663	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.337	0.663	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.337	0.663	0.000
C21 Malignant neoplasm of anus and anal canal	0.337	0.663	0.000
C17 Malignant neoplasm of small intestine	0.337	0.663	0.000
C16 Malignant neoplasm of stomach	0.337	0.663	0.000
C23 Malignant neoplasm of gallbladder	0.337	0.663	0.000
M79.66 Pain in limb (Lower leg)	0.337	0.663	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.336	0.664	0.000
E34 Other endocrine disorders	0.336	0.664	0.000
E32 Diseases of thymus	0.336	0.664	0.000
E31 Polyglandular dysfunction	0.336	0.664	0.000
E30 Disorders of puberty, not elsewhere classified	0.336	0.664	0.000
E29 Testicular dysfunction	0.336	0.664	0.000
E28 Ovarian dysfunction	0.336	0.664	0.000
E27 Other disorders of adrenal gland	0.336	0.664	0.000
E26 Hyperaldosteronism	0.336	0.664	0.000
E25 Adrenogenital disorders	0.336	0.664	0.000
E24 Cushing's syndrome	0.336	0.664	0.000
E23 Hypofunction and other disorders of pituitary gland	0.336	0.664	0.000
E22 Hyperfunction of pituitary gland	0.336	0.664	0.000
E20 Hypoparathyroidism	0.336	0.664	0.000
F41.9 Anxiety disorder, unspecified	0.336	0.664	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.336	0.664	0.000
H40-H42 Glaucoma	0.334	0.666	0.000
E83.4 Disorders of magnesium metabolism	0.334	0.666	0.000
M53 Other dorsopathies, not elsewhere classified	0.333	0.667	0.000
D33.3 Cranial nerves	0.332	0.668	0.000
Z03.4 Observation for suspected myocardial infarction	0.332	0.668	0.000
M18 Arthrosis of first carpometacarpal joint	0.332	0.668	0.000
N17-N19 Renal failure	0.332	0.668	0.000
M79.8 Other specified soft tissue disorders	0.332	0.668	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.332	0.668	0.000
M49 Spondylopathies in diseases classified elsewhere	0.331	0.669	0.000
M46 Other inflammatory spondylopathies	0.331	0.669	0.000
M45 Ankylosing spondylitis	0.331	0.669	0.000
E21.3 Hyperparathyroidism, unspecified	0.331	0.669	0.000
D25.1 Intramural leiomyoma of uterus	0.330	0.670	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.329	0.671	0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.329	0.671	0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.329	0.671	0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.329	0.671	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.329	0.671	0.000
E14 Unspecified diabetes mellitus	0.328	0.672	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.327	0.673	0.000
N20.0 Calculus of kidney	0.327	0.673	0.000
H02 Other disorders of eyelid	0.326	0.674	0.000
Z00.0 General medical examination	0.325	0.675	0.000
F43.2 Adjustment disorders	0.325	0.675	0.000
Chapter XX External causes of morbidity and mortality	0.325	0.675	0.000
M67 Other disorders of synovium and tendon	0.325	0.675	0.000
N60-N64 Disorders of breast	0.325	0.675	0.000
M42 Spinal osteochondrosis	0.324	0.676	0.000
M41 Scoliosis	0.324	0.676	0.000
M40 Kyphosis and lordosis	0.324	0.676	0.000
M90 Osteopathies in diseases classified elsewhere	0.324	0.676	0.000
M88 Paget's disease of bone [osteitis deformans]	0.324	0.676	0.000
M87 Osteonecrosis	0.324	0.676	0.000
M86 Osteomyelitis	0.324	0.676	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.323	0.677	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.323	0.677	0.000
C32 Malignant neoplasm of larynx	0.323	0.677	0.000
C31 Malignant neoplasm of accessory sinuses	0.323	0.677	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.323	0.677	0.000
C37 Malignant neoplasm of thymus	0.323	0.677	0.000
C33 Malignant neoplasm of trachea	0.323	0.677	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.323	0.677	0.000
E65-E68 Obesity and other hyperalimentation	0.322	0.677	0.000
B95-B98 Bacterial, viral and other infectious agents	0.322	0.678	0.000
M79.60 Pain in limb (Multiple sites)	0.322	0.678	0.000
H55-H59 Other disorders of eye and adnexa	0.322	0.678	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.322	0.678	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.322	0.678	0.000
H10-H13 Disorders of conjunctiva	0.322	0.678	0.000
D18.1 Lymphangioma, any site	0.322	0.678	0.000
Z90 Acquired absence of organs, not elsewhere classified	0.322	0.678	0.000
E03.9 Hypothyroidism, unspecified	0.322	0.678	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.320	0.680	0.000
C95 Leukaemia of unspecified cell type	0.320	0.680	0.000
C94 Other leukaemias of specified cell type	0.320	0.680	0.000
C93 Monocytic leukaemia	0.320	0.680	0.000
C92 Myeloid leukaemia	0.320	0.680	0.000
C91 Lymphoid leukaemia	0.320	0.680	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.320	0.680	0.000
C88 Malignant immunoproliferative diseases	0.320	0.680	0.000
C86 Other specified types of T/NK-cell lymphoma	0.320	0.680	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.320	0.680	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.320	0.680	0.000
C81 Hodgkin's disease	0.320	0.680	0.000
O70 Perineal laceration during delivery	0.319	0.681	0.000
M48.06 Spinal stenosis (Lumbar region)	0.319	0.681	0.000
M50.1 Cervical disk disorder with radiculopathy	0.319	0.681	0.000
M79.67 Pain in limb (Ankle and foot)	0.318	0.682	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.318	0.682	0.000
M15 Polyarthrosis	0.318	0.682	0.000
Z12 Special screening examination for neoplasms	0.318	0.682	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.317	0.682	0.000
E83.8 Other disorders of mineral metabolism	0.317	0.682	0.000
E83.3 Disorders of phosphorus metabolism	0.317	0.682	0.000
E83.2 Disorders of zinc metabolism	0.317	0.682	0.000
E83.1 Disorders of iron metabolism	0.317	0.682	0.000
E83.0 Disorders of copper metabolism	0.317	0.682	0.000
O20 Haemorrhage in early pregnancy	0.315	0.684	0.000
Z30 Contraceptive management	0.316	0.684	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.315	0.685	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.315	0.685	0.000
D46 Myelodysplastic syndromes	0.315	0.685	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.315	0.685	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.315	0.685	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.315	0.685	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.315	0.685	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.315	0.685	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.315	0.685	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.315	0.685	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.315	0.685	0.000
O63 Long labour	0.315	0.685	0.000
O36.9 Maternal care for foetal problem, unspecified	0.314	0.686	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.314	0.686	0.000
O36.6 Maternal care for excessive foetal growth	0.314	0.686	0.000
O36.4 Maternal care for intra-uterine death	0.314	0.686	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.314	0.686	0.000
O36.2 Maternal care for hydrops foetalis	0.314	0.686	0.000
O36.1 Maternal care for other isoimmunisation	0.314	0.686	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.314	0.686	0.000
F03 Unspecified dementia	0.314	0.686	0.000
O02 Other abnormal products of conception	0.314	0.686	0.000
H90 Conductive and sensorineural hearing loss	0.314	0.686	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.313	0.686	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.313	0.686	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.313	0.686	0.000
L20-L30 Dermatitis and eczema	0.313	0.687	0.000
Z60 Problems related to social environment	0.312	0.687	0.000
Z37.0 Single live birth	0.312	0.688	0.000
D06.9 Cervix, unspecified	0.311	0.689	0.000
L50-L54 Urticaria and erythema	0.311	0.689	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.311	0.689	0.000
N40-N51 Diseases of male genital organs	0.311	0.689	0.000
C15.5 Lower third of oesophagus	0.311	0.689	0.000
Z93 Artificial opening status	0.311	0.689	0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.311	0.689	0.000
Z92 Personal history of medical treatment	0.310	0.690	0.000
B99-B99 Other infectious diseases	0.308	0.691	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.308	0.691	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.308	0.691	0.000
B65-B83 Helminthiases	0.308	0.691	0.000
B50-B64 Protozoal diseases	0.308	0.691	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.308	0.691	0.000
B15-B19 Viral hepatitis	0.308	0.691	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.308	0.691	0.000
A80-A89 Viral infections of the central nervous system	0.308	0.691	0.000
A75-A79 Rickettsioses	0.308	0.691	0.000
A70-A74 Other diseases caused by chlamydiae	0.308	0.691	0.000
A65-A69 Other spirochaetal diseases	0.308	0.691	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.308	0.691	0.000
A20-A28 Certain zoonotic bacterial diseases	0.308	0.691	0.000
A15-A19 Tuberculosis	0.308	0.691	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.308	0.692	0.000
M54 Dorsalgia	0.308	0.692	0.000
O72 Postpartum haemorrhage	0.308	0.692	0.000
H73.8 Other specified disorders of tympanic membrane	0.307	0.692	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.307	0.692	0.000
M66 Spontaneous rupture of synovium and tendon	0.307	0.692	0.000
J34 Other disorders of nose and nasal sinuses	0.307	0.693	0.000
P90-P96 Other disorders originating in the perinatal period	0.306	0.694	0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.306	0.694	0.000
P75-P78 Digestive system disorders of fetus and newborn	0.306	0.694	0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.306	0.694	0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.306	0.694	0.000
P35-P39 Infections specific to the perinatal period	0.306	0.694	0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.306	0.694	0.000
P10-P15 Birth trauma	0.306	0.694	0.000
P05-P08 Disorders related to length of gestation and fetal growth	0.306	0.694	0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.306	0.694	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.306	0.694	0.000
Q80-Q89 Other congenital malformations	0.306	0.694	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.306	0.694	0.000
Q60-Q64 Congenital malformations of the urinary system	0.306	0.694	0.000
Q50-Q56 Congenital malformations of genital organs	0.306	0.694	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.306	0.694	0.000
Q35-Q37 Cleft lip and cleft palate	0.306	0.694	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.306	0.694	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.306	0.694	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.306	0.694	0.000
Q00-Q07 Congenital malformations of the nervous system	0.306	0.694	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.306	0.694	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.306	0.694	0.000
M51 Other intervertebral disk disorders	0.306	0.694	0.000
O80.0 Spontaneous vertex delivery	0.306	0.694	0.000
A00-A09 Intestinal infectious diseases	0.305	0.695	0.000
M17 Gonarthrosis [arthrosis of knee]	0.305	0.695	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations